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Conserved domains on  [gi|942071073|ref|WP_055285378|]
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MULTISPECIES: AAA family ATPase [Collinsella]

Protein Classification

AAA family ATPase( domain architecture ID 11437845)

AAA family ATPase similar to (d)CMP kinase, which catalyzes the phosphorylation of cytidine monophosphate (CMP) or dCMP to produce cytidine diphosphate (CDP) or dCDP, using ATP as the preferred phosphoryl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
12-205 4.52e-54

Cytidylate kinase [Nucleotide transport and metabolism];


:

Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 170.78  E-value: 4.52e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  12 VITIARDFGAEGHEIGRMLADELGIPLYDNELLVRASLRAGESLDKMAAYDERLAVENMAFLPDrydarsySDKLFQKMS 91
Cdd:COG1102    2 VITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKAPSLLYRDTAE-------EDEIDRALD 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  92 QVILDLGETESCIIEGRLSDYLLRNNPNHIAVLVTAPFEDRVEIVRKKRGLNKKKGAKLVKQQQKAREAFYKRYSAGKWK 171
Cdd:COG1102   75 KVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYYKYYYGIDWG 154

                        170       180       190
                 ....*....|....*....|....*....|....
gi 942071073 172 MTSGKDIVVNRAKLGREGCKDVIAAAYRYKVAQL 205
Cdd:COG1102  155 DPSNYDLVINTSRLGIEEAVDLILAAIEAREKKE 188
 
Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
12-205 4.52e-54

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 170.78  E-value: 4.52e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  12 VITIARDFGAEGHEIGRMLADELGIPLYDNELLVRASLRAGESLDKMAAYDERLAVENMAFLPDrydarsySDKLFQKMS 91
Cdd:COG1102    2 VITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKAPSLLYRDTAE-------EDEIDRALD 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  92 QVILDLGETESCIIEGRLSDYLLRNNPNHIAVLVTAPFEDRVEIVRKKRGLNKKKGAKLVKQQQKAREAFYKRYSAGKWK 171
Cdd:COG1102   75 KVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYYKYYYGIDWG 154

                        170       180       190
                 ....*....|....*....|....*....|....
gi 942071073 172 MTSGKDIVVNRAKLGREGCKDVIAAAYRYKVAQL 205
Cdd:COG1102  155 DPSNYDLVINTSRLGIEEAVDLILAAIEAREKKE 188
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
 12-184 9.01e-46

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 149.32  E-value: 9.01e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073   12 VITIARDFGAEGHEIGRMLADELGIPLYDNELLVRASLRAGESLDKMAAYDERLA----VENMAFLPDRYDArSYSDKLF 87
Cdd:pfam13189   1 VITISRQYGSGGTTIAKKLAEKLGYPFYDREILDEIAKELGISEEEFELFDEKSRlssfLYSLAGGRVRGDA-LSDDRLF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073   88 QKMSQVILDLGETESCIIEGRLSDYLLRNNPNHIAVLVTAPFEDRVEIVRKKRGLNKKKGAKLVKQQQKAREAFYKRYSA 167
Cdd:pfam13189  80 DAQSKVIRELAAEDNCVIVGRGADYILKDIPNVLRVFLTAPLEDRVKRVMEREGLSEEEARELIKETDKRRAKYYKYYTG 159

                         170
                  ....*....|....*..
gi 942071073  168 GKWKMTSGKDIVVNRAK 184
Cdd:pfam13189 160 KDWGDAENYDLVINTSK 176
PRK04182 PRK04182
cytidylate kinase; Provisional
 26-197 3.47e-04

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 39.79  E-value: 3.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  26 IGRMLADELGIPLYDnellvraslrAGESLDKMAAydER---------LAVENMAFlpDRY-DARsysdklfqkmsqvIL 95
Cdd:PRK04182  16 VARLLAEKLGLKHVS----------AGEIFRELAK--ERgmsleefnkYAEEDPEI--DKEiDRR-------------QL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  96 DLGETE-SCIIEGRLSDYLLRNNPnHIAVLVTAPFEDRVEIVRKKRGLNKKKgaklVKQQQKAREAF-YKRYsagkWKM- 172
Cdd:PRK04182  69 EIAEKEdNVVLEGRLAGWMAKDYA-DLKIWLKAPLEVRAERIAEREGISVEE----ALEETIEREESeAKRY----KEYy 139

                        170       180       190
                 ....*....|....*....|....*....|.
gi 942071073 173 ------TSGKDIVVNRAKLGREGCKDVIAAA 197
Cdd:PRK04182 140 gididdLSIYDLVINTSRWDPEGVFDIILTA 170
 
Name Accession Description Interval E-value
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
12-205 4.52e-54

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 170.78  E-value: 4.52e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  12 VITIARDFGAEGHEIGRMLADELGIPLYDNELLVRASLRAGESLDKMAAYDERLAVENMAFLPDrydarsySDKLFQKMS 91
Cdd:COG1102    2 VITISREPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSEEEFEKLDEKAPSLLYRDTAE-------EDEIDRALD 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  92 QVILDLGETESCIIEGRLSDYLLRNNPNHIAVLVTAPFEDRVEIVRKKRGLNKKKGAKLVKQQQKAREAFYKRYSAGKWK 171
Cdd:COG1102   75 KVIRELARKGNCVIVGRLADWILRDRPNVLKVFLTAPLEVRVKRIAEREGISEEEAEKEIKKRDKSRAKYYKYYYGIDWG 154

                        170       180       190
                 ....*....|....*....|....*....|....
gi 942071073 172 MTSGKDIVVNRAKLGREGCKDVIAAAYRYKVAQL 205
Cdd:COG1102  155 DPSNYDLVINTSRLGIEEAVDLILAAIEAREKKE 188
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
 12-184 9.01e-46

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 149.32  E-value: 9.01e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073   12 VITIARDFGAEGHEIGRMLADELGIPLYDNELLVRASLRAGESLDKMAAYDERLA----VENMAFLPDRYDArSYSDKLF 87
Cdd:pfam13189   1 VITISRQYGSGGTTIAKKLAEKLGYPFYDREILDEIAKELGISEEEFELFDEKSRlssfLYSLAGGRVRGDA-LSDDRLF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073   88 QKMSQVILDLGETESCIIEGRLSDYLLRNNPNHIAVLVTAPFEDRVEIVRKKRGLNKKKGAKLVKQQQKAREAFYKRYSA 167
Cdd:pfam13189  80 DAQSKVIRELAAEDNCVIVGRGADYILKDIPNVLRVFLTAPLEDRVKRVMEREGLSEEEARELIKETDKRRAKYYKYYTG 159

                         170
                  ....*....|....*..
gi 942071073  168 GKWKMTSGKDIVVNRAK 184
Cdd:pfam13189 160 KDWGDAENYDLVINTSK 176
PRK04182 PRK04182
cytidylate kinase; Provisional
 26-197 3.47e-04

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 39.79  E-value: 3.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  26 IGRMLADELGIPLYDnellvraslrAGESLDKMAAydER---------LAVENMAFlpDRY-DARsysdklfqkmsqvIL 95
Cdd:PRK04182  16 VARLLAEKLGLKHVS----------AGEIFRELAK--ERgmsleefnkYAEEDPEI--DKEiDRR-------------QL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 942071073  96 DLGETE-SCIIEGRLSDYLLRNNPnHIAVLVTAPFEDRVEIVRKKRGLNKKKgaklVKQQQKAREAF-YKRYsagkWKM- 172
Cdd:PRK04182  69 EIAEKEdNVVLEGRLAGWMAKDYA-DLKIWLKAPLEVRAERIAEREGISVEE----ALEETIEREESeAKRY----KEYy 139

                        170       180       190
                 ....*....|....*....|....*....|.
gi 942071073 173 ------TSGKDIVVNRAKLGREGCKDVIAAA 197
Cdd:PRK04182 140 gididdLSIYDLVINTSRWDPEGVFDIILTA 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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