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Conserved domains on  [gi|949724212|ref|WP_057067350|]
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MULTISPECIES: glutathione ABC transporter ATP-binding protein GsiA [Citrobacter]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11484638)

ABC transporter ATP-binding protein similar to GsiA, the ATPase catalytic subunit of the ABC transporter complex GsiABCD, which is responsible for coupling the energy of ATP hydrolysis to the import of glutathione

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1-623 0e+00

glutathione transporter ATP-binding protein; Provisional


:

Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 1217.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   1 MPHSDELDASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLL 80
Cdd:PRK10261   1 MPHSDELDARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  81 RRRNRQVIELGEQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKA 160
Cdd:PRK10261  81 RRRSRQVIELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQT 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVL 240
Cdd:PRK10261 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 241 VMYQGEAVETGSVEQIFHAPQHPYTKALLAAVPQLGAMNGHELPRRFPLISLHDPSHVEPQTEQDTVVEGEPILRVRNLV 320
Cdd:PRK10261 241 VMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQDTVVDGEPILQVRNLV 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 321 TRFPLRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLR 400
Cdd:PRK10261 321 TRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALR 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 401 RDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL 480
Cdd:PRK10261 401 RDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 481 NPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYT 560
Cdd:PRK10261 481 NPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYT 560
                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 561 RKLMAAVPVADPSHHRPQRVLLSDDIPSNIRKRGEEISPVSLQLVGPGHYVARPLPENALSRL 623
Cdd:PRK10261 561 RKLMAAVPVADPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR 623
 
Name Accession Description Interval E-value
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1-623 0e+00

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 1217.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   1 MPHSDELDASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLL 80
Cdd:PRK10261   1 MPHSDELDARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  81 RRRNRQVIELGEQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKA 160
Cdd:PRK10261  81 RRRSRQVIELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQT 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVL 240
Cdd:PRK10261 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 241 VMYQGEAVETGSVEQIFHAPQHPYTKALLAAVPQLGAMNGHELPRRFPLISLHDPSHVEPQTEQDTVVEGEPILRVRNLV 320
Cdd:PRK10261 241 VMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQDTVVDGEPILQVRNLV 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 321 TRFPLRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLR 400
Cdd:PRK10261 321 TRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALR 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 401 RDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL 480
Cdd:PRK10261 401 RDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 481 NPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYT 560
Cdd:PRK10261 481 NPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYT 560
                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 561 RKLMAAVPVADPSHHRPQRVLLSDDIPSNIRKRGEEISPVSLQLVGPGHYVARPLPENALSRL 623
Cdd:PRK10261 561 RKLMAAVPVADPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR 623
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
12-571 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 823.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVScDEMLLRRRnrqviELG 91
Cdd:COG4172    6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPS-GSILFDGQ-----DLL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSG 171
Cdd:COG4172   80 GLSERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSG 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:COG4172  160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQG 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 252 SVEQIFHAPQHPYTKALLAAVPQLgamnghelprrfplislhDPSHVEPqteqdtvvEGEPILRVRNLVTRFPLRSGILN 331
Cdd:COG4172  240 PTAELFAAPQHPYTRKLLAAEPRG------------------DPRPVPP--------DAPPLLEARDLKVWFPIKRGLFR 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 332 RVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQrGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDPY 411
Cdd:COG4172  294 RTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPSE-GEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPF 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 412 ASLDPRQTVGYSILEPLRVHGL-LQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:COG4172  373 GSLSPRMTVGQIIAEGLRVHGPgLSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEP 452
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 491 VSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVPVA 570
Cdd:COG4172  453 TSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLL 532

                 .
gi 949724212 571 D 571
Cdd:COG4172  533 E 533
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
313-546 2.12e-111

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 333.32  E-value: 2.12e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLA 392
Cdd:cd03257    1 LLEVKNLSVSFPTGGG-------SVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWL-LERVGLLPEHAWRYPHEFSGGQRQR 471
Cdd:cd03257   74 RRLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLlLVGVGLPEEVLNRYPHELSGGQRQR 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03257  154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
31-271 1.24e-76

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 243.43  E-value: 1.24e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLlrrRNRQVIELGeqsasqmrhVRGADIAMIF 110
Cdd:TIGR02770   1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILL---DGRPLLPLS---------IRGRHIATIM 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  111 QEPMTSLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:TIGR02770  69 QNPRTAFNPLFTMGNHAIETLRSL-GKLSKQARALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFL 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLA 270
Cdd:TIGR02770 148 IADEPTTDLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLS 227

                  .
gi 949724212  271 A 271
Cdd:TIGR02770 228 A 228
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
340-489 6.38e-39

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 140.09  E-value: 6.38e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaASKLQPLRRDIQFIFQDPyaSLDPRQT 419
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLT---DDERKSLRKEIGYVFQDP--QLFPRLT 75
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212  420 VGYSILEPLRVHGLLQGDAGSkRVAWLLERVGL---LPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADE 489
Cdd:pfam00005  76 VRENLRLGLLLKGLSKREKDA-RAEEALEKLGLgdlADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDE 147
GguA NF040905
sugar ABC transporter ATP-binding protein;
29-543 6.01e-22

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 99.48  E-value: 6.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHL---IEQAG---GEVSCDEMLLRRRNrqvIELGEQsasqmrhvR 102
Cdd:NF040905  14 VKALDDVNLSVREGEIHALCGENGAGKS----TLMKVlsgVYPHGsyeGEILFDGEVCRFKD---IRDSEA--------L 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 103 GadIAMIFQE----PMTSlnpvftvgeqIAESIRL-HQGASH-----EEAMVEAKRMLDQVRIPEAKAILSRyphQLSGG 172
Cdd:NF040905  79 G--IVIIHQElaliPYLS----------IAENIFLgNERAKRgvidwNETNRRARELLAKVGLDESPDTLVT---DIGVG 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVL-QQDMSmgVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:NF040905 144 KQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELkAQGIT--SIIISHKLNEIRRVADSITVLRDGRTIETL 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 252 SVEQifhapqhpytkallAAVPQ---LGAMNGHELPRRFPlisLHDPShvepqteqdtvvEGEPILRVRNLVTRFPLRSG 328
Cdd:NF040905 222 DCRA--------------DEVTEdriIRGMVGRDLEDRYP---ERTPK------------IGEVVFEVKNWTVYHPLHPE 272
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 329 ilnrvtREVhaVENVSFDLWPGETLSLVGESGCGK-----STTGRALLRLVesqRGEIIFNGQRIDTLAASKlqPLRRDI 403
Cdd:NF040905 273 ------RKV--VDDVSLNVRRGEIVGIAGLMGAGRtelamSVFGRSYGRNI---SGTVFKDGKEVDVSTVSD--AIDAGL 339
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 404 QfifqdpYASLDpRQTVGYSILEPLRVHGLLqgdAGSKRVAwlleRVGLLPEH-----AWRYPHEF-------------- 464
Cdd:NF040905 340 A------YVTED-RKGYGLNLIDDIKRNITL---ANLGKVS----RRGVIDENeeikvAEEYRKKMniktpsvfqkvgnl 405
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 465 SGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGRIT 483
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
168-547 4.01e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 88.64  E-value: 4.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDM-SMGVIFITHDMgvvaDIADR---VLVMY 243
Cdd:NF033858 136 KLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVLVATAYM----EEAERfdwLVAMD 211
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 244 QGEAVETGSveqifhapqhpyTKALLAavpQLGAMNgheLPRRFplISL--------HDPSHVEPQTEQDtvvEGEPILR 315
Cdd:NF033858 212 AGRVLATGT------------PAELLA---RTGADT---LEAAF--IALlpeekrrgHQPVVIPPRPADD---DDEPAIE 268
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 316 VRNLVTRFplrsGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTlaask 395
Cdd:NF033858 269 ARGLTMRF----G-------DFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA----- 332
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 396 lqplrRDIqfifqdpyaslDPRQTVGY-----------SILEPLRVHGLL---QGDAGSKRVAWLLERVGLLpEHAWRYP 461
Cdd:NF033858 333 -----GDI-----------ATRRRVGYmsqafslygelTVRQNLELHARLfhlPAAEIAARVAEMLERFDLA-DVADALP 395
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 HEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAyLFIS-HDMAVVERIShRVAVMYLG 540
Cdd:NF033858 396 DSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVT-IFIStHFMNEAERCD-RISLMHAG 473

                 ....*..
gi 949724212 541 QIVEIGT 547
Cdd:NF033858 474 RVLASDT 480
GguA NF040905
sugar ABC transporter ATP-binding protein;
313-544 2.70e-14

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 75.60  E-value: 2.70e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPlrsGilnrvtreVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLVE------SQRGEIIFNGQ 386
Cdd:NF040905   1 ILEMRGITKTFP---G--------VKALDDVNLSVREGEIHALCGENGAGKST----LMKVLSgvyphgSYEGEILFDGE 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 --RIDTLAASKlqplRRDIQFIFQDpyASLDPRQTVGYSIL---EPLRvHGLLQGDAGSKRVAWLLERVGlLPEHawryP 461
Cdd:NF040905  66 vcRFKDIRDSE----ALGIVIIHQE--LALIPYLSIAENIFlgnERAK-RGVIDWNETNRRARELLAKVG-LDES----P 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 HEFSG----GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVM 537
Cdd:NF040905 134 DTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVL 212

                 ....*..
gi 949724212 538 YLGQIVE 544
Cdd:NF040905 213 RDGRTIE 219
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
31-242 6.16e-14

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 70.73  E-value: 6.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemLLRrrnrqvielgeQSASQMRHVRGADIAMIF 110
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKS----TLLKVL--AG--------VLR-----------PTSGTVRRAGGARVAYVP 61
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEpmTSLNPVF--TVGEQIAESIRLHQGAS-----HEEAMVEakRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMAL 183
Cdd:NF040873  62 QR--SEVPDSLplTVRDLVAMGRWARRGLWrrltrDDRAAVD--DALERVGL---ADLAGRQLGELSGGQRQRALLAQGL 134
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADiADRVLVM 242
Cdd:NF040873 135 AQEADLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRR-ADPCVLL 191
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
339-534 5.77e-12

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 64.95  E-value: 5.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIifngqRIDTLAASKLQPLRRDIqfifqDPYASLDPRQ 418
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----RRAGGARVAYVPQRSEV-----PDSLPLTVRD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSI 498
Cdd:NF040873  77 LVAMGRWARRGLWRRLTRDD-RAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAES 154
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 949724212 499 RGQIINLMLDLQRElGIAYLFISHDMAVVERISHRV 534
Cdd:NF040873 155 RERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
138-256 2.64e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 59.36  E-value: 2.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 138 SHEEAMVEAKRMLDQVRIPEAKAilsRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQD 217
Cdd:NF000106 117 SRKDARARADELLERFSLTEAAG---RAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD 193
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 949724212 218 MSMgVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:NF000106 194 GAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-246 7.06e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.99  E-value: 7.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    41 RGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrrrnrqvielgeqsasqmrhvrgadiamifqepmtslnpv 120
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV----------------------------------------------- 33
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   121 ftvgeqiaesirlhqgasheeAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALD 200
Cdd:smart00382  34 ---------------------IYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLD 92
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212   201 VTIQAQILQLI-----KVLQQDMSMGVIFITHDM-----GVVADIADRVLVMYQGE 246
Cdd:smart00382  93 AEQEALLLLLEelrllLLLKSEKNLTVILTTNDEkdlgpALLRRRFDRRIVLLLIL 148
GguA NF040905
sugar ABC transporter ATP-binding protein;
12-248 7.47e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.10  E-value: 7.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLM-----HLIeqaGGEVSCDEMLLRRRN-R 85
Cdd:NF040905 257 VFEVKNWTVYHPLHPERK-VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFgrsygRNI---SGTVFKDGKEVDVSTvS 332
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  86 QVIELGEQSASQMRHVRGadiamifqepmtsLNpvftVGEQIAESIRL--HQGAS-------HEEAMVeAKRMLDQVRIP 156
Cdd:NF040905 333 DAIDAGLAYVTEDRKGYG-------------LN----LIDDIKRNITLanLGKVSrrgvideNEEIKV-AEEYRKKMNIK 394
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 157 ----EAKAIlsryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVV 232
Cdd:NF040905 395 tpsvFQKVG------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINEL-AAEGKGVIVISSELPEL 467
                        250
                 ....*....|....*.
gi 949724212 233 ADIADRVLVMYQGEAV 248
Cdd:NF040905 468 LGMCDRIYVMNEGRIT 483
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
336-546 3.15e-06

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 49.73  E-value: 3.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTtGRALLRLVESQRGEiifNGQRIDTLAASKlQPLRRDIqfifqDPYASLD 415
Cdd:NF000106  25 EVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGR---RPWRF*TWCANR-RALRRTI-----G*HRPVR 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILEPLRVHG----LLQGDAGSkRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:NF000106  95 *GRRESFSGRENLYMIGr*ldLSRKDARA-RADELLERFSL-TEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 492 SALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:NF000106 173 TGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADG 226
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
31-256 1.53e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 45.12  E-value: 1.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGE-------VSCDEMLLRRRN---------------RQVI 88
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEawlfgqpVDAGDIATRRRVgymsqafslygeltvRQNL 360
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELgeqsasqmrHVRgadiamIFQEPmtslnpvftvGEQIAESIrlhqgasheEAMVEaKRMLDQVripeakaiLSRYPHQ 168
Cdd:NF033858 361 EL---------HAR------LFHLP----------AAEIAARV---------AEMLE-RFDLADV--------ADALPDS 397
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQ-LIKVLQQDmsmGV-IFI-THDMGvVADIADRVLVMYQG 245
Cdd:NF033858 398 LPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRlLIELSRED---GVtIFIsTHFMN-EAERCDRISLMHAG 473
                        250
                 ....*....|.
gi 949724212 246 EAVETGSVEQI 256
Cdd:NF033858 474 RVLASDTPAAL 484
 
Name Accession Description Interval E-value
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1-623 0e+00

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 1217.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   1 MPHSDELDASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLL 80
Cdd:PRK10261   1 MPHSDELDARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  81 RRRNRQVIELGEQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKA 160
Cdd:PRK10261  81 RRRSRQVIELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQT 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVL 240
Cdd:PRK10261 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 241 VMYQGEAVETGSVEQIFHAPQHPYTKALLAAVPQLGAMNGHELPRRFPLISLHDPSHVEPQTEQDTVVEGEPILRVRNLV 320
Cdd:PRK10261 241 VMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQDTVVDGEPILQVRNLV 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 321 TRFPLRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLR 400
Cdd:PRK10261 321 TRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALR 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 401 RDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL 480
Cdd:PRK10261 401 RDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 481 NPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYT 560
Cdd:PRK10261 481 NPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYT 560
                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 561 RKLMAAVPVADPSHHRPQRVLLSDDIPSNIRKRGEEISPVSLQLVGPGHYVARPLPENALSRL 623
Cdd:PRK10261 561 RKLMAAVPVADPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR 623
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
12-571 0e+00

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 823.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVScDEMLLRRRnrqviELG 91
Cdd:COG4172    6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPS-GSILFDGQ-----DLL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSG 171
Cdd:COG4172   80 GLSERELRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSG 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:COG4172  160 GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQG 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 252 SVEQIFHAPQHPYTKALLAAVPQLgamnghelprrfplislhDPSHVEPqteqdtvvEGEPILRVRNLVTRFPLRSGILN 331
Cdd:COG4172  240 PTAELFAAPQHPYTRKLLAAEPRG------------------DPRPVPP--------DAPPLLEARDLKVWFPIKRGLFR 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 332 RVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQrGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDPY 411
Cdd:COG4172  294 RTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIPSE-GEIRFDGQDLDGLSRRALRPLRRRMQVVFQDPF 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 412 ASLDPRQTVGYSILEPLRVHGL-LQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:COG4172  373 GSLSPRMTVGQIIAEGLRVHGPgLSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEP 452
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 491 VSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVPVA 570
Cdd:COG4172  453 TSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLL 532

                 .
gi 949724212 571 D 571
Cdd:COG4172  533 E 533
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
10-573 0e+00

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 706.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFEQeqQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGgevscdemllrRRNRQVIE 89
Cdd:COG1123    2 TPLLEVRDLSVRYPG--GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGG-----------RISGEVLL 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGEQSASQMRHVRGADIAMIFQEPMTSLNPVfTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPeakAILSRYPHQL 169
Cdd:COG1123   69 DGRDLLELSEALRGRRIGMVFQDPMTQLNPV-TVGDQIAEALEN-LGLSRAEARARVLELLEAVGLE---RRLDRYPHQL 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVE 249
Cdd:COG1123  144 SGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVE 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 250 TGSVEQIFHAPQhpytkaLLAAVPQLGAMNGHELPRRfplislhdpshvepqteqdtvVEGEPILRVRNLVTRFPLRSGi 329
Cdd:COG1123  224 DGPPEEILAAPQ------ALAAVPRLGAARGRAAPAA---------------------AAAEPLLEVRNLSKRYPVRGK- 275
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 330 lnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQD 409
Cdd:COG1123  276 -----GGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRELRRRVQMVFQD 350
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 410 PYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADE 489
Cdd:COG1123  351 PYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRYPHELSGGQRQRVAIARALALEPKLLILDE 430
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 490 SVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVPV 569
Cdd:COG1123  431 PTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHPYTRALLAAVPS 510

                 ....
gi 949724212 570 ADPS 573
Cdd:COG1123  511 LDPA 514
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
9-565 0e+00

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 550.85  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNrqvi 88
Cdd:PRK15134   2 TQPLLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVVYPSGDIRFHGES---- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 eLGEQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQ 168
Cdd:PRK15134  78 -LLHASEQTLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQ 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAV 248
Cdd:PRK15134 157 LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCV 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 249 ETGSVEQIFHAPQHPYTKALLAAVPQlgamnGHELPrrfplislhdpshvepqTEQDTvvegEPILRVRNLVTRFPLRSG 328
Cdd:PRK15134 237 EQNRAATLFSAPTHPYTQKLLNSEPS-----GDPVP-----------------LPEPA----SPLLDVEQLQVAFPIRKG 290
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 329 ILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQrGEIIFNGQRIDTLAASKLQPLRRDIQFIFQ 408
Cdd:PRK15134 291 ILKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQ-GEIWFDGQPLHNLNRRQLLPVRHRIQVVFQ 369
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 409 DPYASLDPRQTVGYSILEPLRVH-GLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIA 487
Cdd:PRK15134 370 DPNSSLNPRLNVLQIIEEGLRVHqPTLSAAQREQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIIL 449
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 488 DESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMA 565
Cdd:PRK15134 450 DEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLA 527
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
309-619 1.54e-170

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 488.09  E-value: 1.54e-170
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 309 EGEPILRVRNLVTRFPLRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRI 388
Cdd:COG4608    3 MAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 389 DTLAASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQ 468
Cdd:COG4608   83 TGLSGRELRPLRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFSGGQ 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 469 RQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTR 548
Cdd:COG4608  163 RQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPR 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 549 RAVFENPQHPYTRKLMAAVPVADPSHHRpQRVLLSDDIPSNI-----------------RKRGEEisPVsLQLVGPGHYV 611
Cdd:COG4608  243 DELYARPLHPYTQALLSAVPVPDPERRR-ERIVLEGDVPSPLnppsgcrfhtrcpyaqdRCATEE--PP-LREVGPGHQV 318

                 ....*...
gi 949724212 612 ARPLPENA 619
Cdd:COG4608  319 ACHLAEEG 326
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
12-277 3.62e-144

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 420.61  E-value: 3.62e-144
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIE---QAGGEVscdemLLRRRNrqvi 88
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEI-----LFDGED---- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 eLGEQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQ 168
Cdd:COG0444   72 -LLKLSEKELRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHE 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAV 248
Cdd:COG0444  151 LSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIV 230
                        250       260
                 ....*....|....*....|....*....
gi 949724212 249 ETGSVEQIFHAPQHPYTKALLAAVPQLGA 277
Cdd:COG0444  231 EEGPVEELFENPRHPYTRALLSSIPRLDP 259
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
313-612 5.75e-141

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 412.52  E-value: 5.75e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQR---GEIIFNGQRID 389
Cdd:COG0444    1 LLEVRNLKVYFPTRRG-------VVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGitsGEILFDGEDLL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 390 TLAASKLQPLR-RDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLP--EHAWRYPHEFSG 466
Cdd:COG0444   74 KLSEKELRKIRgREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDpeRRLDRYPHELSG 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 467 GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:COG0444  154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEG 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 547 TRRAVFENPQHPYTRKLMAAVPVADPSHHRpqRVLLSDDIPSNI---------------RKRGEEISPVsLQLVGPGHYV 611
Cdd:COG0444  234 PVEELFENPRHPYTRALLSSIPRLDPDGRR--LIPIPGEPPSLLnppsgcrfhprcpyaMDRCREEEPP-LREVGPGHRV 310

                 .
gi 949724212 612 A 612
Cdd:COG0444  311 A 311
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
310-588 1.64e-113

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 342.71  E-value: 1.64e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 310 GEPILRVRNLVTRFPLRSGILnRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQriD 389
Cdd:PRK11308   2 QQPLLQAIDLKKHYPVKRGLF-KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQ--D 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 390 TLAASK--LQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGG 467
Cdd:PRK11308  79 LLKADPeaQKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSGG 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 468 QRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:PRK11308 159 QRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGT 238
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 949724212 548 RRAVFENPQHPYTRKLMAAVPVADPSHHRPqRVLLSDDIPS 588
Cdd:PRK11308 239 KEQIFNNPRHPYTQALLSATPRLNPDDRRE-RIKLTGELPS 278
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
306-590 2.93e-112

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 339.37  E-value: 2.93e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 306 TVVEGEPILRVRNLVTRFPLRSG--ILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIF 383
Cdd:PRK15079   1 VTEGKKVLLEVADLKVHFDIKDGkqWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAW 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 384 NGQRIDTLAASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRV-HGLLQGDAGSKRVAWLLERVGLLPEHAWRYPH 462
Cdd:PRK15079  81 LGKDLLGMKDDEWRAVRSDIQMIFQDPLASLNPRMTIGEIIAEPLRTyHPKLSRQEVKDRVKAMMLKVGLLPNLINRYPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 463 EFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:PRK15079 161 EFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHA 240
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 949724212 543 VEIGTRRAVFENPQHPYTRKLMAAVPVADPSHHRPQRV-LLSDDIPSNI 590
Cdd:PRK15079 241 VELGTYDEVYHNPLHPYTKALMSAVPIPDPDLERNKTIqLLEGELPSPI 289
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
313-546 2.12e-111

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 333.32  E-value: 2.12e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLA 392
Cdd:cd03257    1 LLEVKNLSVSFPTGGG-------SVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWL-LERVGLLPEHAWRYPHEFSGGQRQR 471
Cdd:cd03257   74 RRLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLlLVGVGLPEEVLNRYPHELSGGQRQR 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03257  154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
9-284 5.13e-111

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 336.31  E-value: 5.13e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAG---GEVscdemllRRRNR 85
Cdd:PRK09473   9 ADALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGrigGSA-------TFNGR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  86 QVIELGEQsasQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRY 165
Cdd:PRK09473  82 EILNLPEK---ELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMY 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 166 PHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQG 245
Cdd:PRK09473 159 PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAG 238
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 949724212 246 EAVETGSVEQIFHAPQHPYTKALLAAVPQLGAmNGHELP 284
Cdd:PRK09473 239 RTMEYGNARDVFYQPSHPYSIGLLNAVPRLDA-EGESLL 276
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
12-251 2.26e-106

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 320.22  E-value: 2.26e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrNRQVIELG 91
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFD-------GKDLLKLS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQsasqMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMvEAKRMLDQVRIPEAKAILSRYPHQLSG 171
Cdd:cd03257   74 RR----LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEAR-KEAVLLLLVGVGLPEEVLNRYPHELSG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03257  149 GQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
314-568 8.56e-103

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 312.12  E-value: 8.56e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPLRSgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdTLAA 393
Cdd:COG1124    2 LEVRNLSVSYGQGG-------RRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPV-TRRR 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKlqPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAgskRVAWLLERVGLLPEHAWRYPHEFSGGQRQRIC 473
Cdd:COG1124   74 RK--AFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIHGLPDREE---RIAELLEQVGLPPSFLDRYPHQLSGGQRQRVA 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 474 IARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:COG1124  149 IARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLA 228
                        250
                 ....*....|....*
gi 949724212 554 NPQHPYTRKLMAAVP 568
Cdd:COG1124  229 GPKHPYTRELLAASL 243
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
311-583 2.33e-99

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 313.16  E-value: 2.33e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFplRSGilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ----RGEIIFNGQ 386
Cdd:COG4172    4 MPLLSVEDLSVAF--GQG-----GGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPaahpSGSILFDGQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDTLAASKLQPLR-RDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLlPEHAWR---YPH 462
Cdd:COG4172   77 DLLGLSERELRRIRgNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGI-PDPERRldaYPH 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 463 EFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:COG4172  156 QLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEI 235
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 949724212 543 VEIGTRRAVFENPQHPYTRKLMAAVPVADPSHHRP-QRVLLS 583
Cdd:COG4172  236 VEQGPTAELFAAPQHPYTRKLLAAEPRGDPRPVPPdAPPLLE 277
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
12-277 2.86e-97

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 300.51  E-value: 2.86e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGgEVSCDEMLLRRRNRQVIelg 91
Cdd:PRK11022   3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPG-RVMAEKLEFNGQDLQRI--- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 eqSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSG 171
Cdd:PRK11022  79 --SEKERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSG 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:PRK11022 157 GMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETG 236
                        250       260
                 ....*....|....*....|....*.
gi 949724212 252 SVEQIFHAPQHPYTKALLAAVPQLGA 277
Cdd:PRK11022 237 KAHDIFRAPRHPYTQALLRALPEFAQ 262
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
311-566 3.27e-94

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 290.59  E-value: 3.27e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSGILNRvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDT 390
Cdd:COG4167    2 SALLEVRNLSKTFKYRTGLFRR--QQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEY 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 laaSKLQPLRRDIQFIFQDPYASLDPRQTVGySILE-PLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQR 469
Cdd:COG4167   80 ---GDYKYRCKHIRMIFQDPNTSLNPRLNIG-QILEePLRLNTDLTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQK 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:COG4167  156 QRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTA 235
                        250
                 ....*....|....*..
gi 949724212 550 AVFENPQHPYTRKLMAA 566
Cdd:COG4167  236 EVFANPQHEVTKRLIES 252
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
22-273 8.22e-89

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 278.92  E-value: 8.22e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  22 FEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQSASQMRHV 101
Cdd:COG4608   24 FGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDG----------QDITGLSGRELRPL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 102 RgADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAilSRYPHQLSGGMRQRVMIAM 181
Cdd:COG4608   94 R-RRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHA--DRYPHEFSGGQRQRIGIAR 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQ 261
Cdd:COG4608  171 ALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDELYARPL 250
                        250
                 ....*....|..
gi 949724212 262 HPYTKALLAAVP 273
Cdd:COG4608  251 HPYTQALLSAVP 262
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
13-277 1.11e-82

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 260.12  E-value: 1.11e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRqvielge 92
Cdd:COG1124    2 LEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRR------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 qsasqmRHVRGaDIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEamvEAKRMLDQVRIPEAkaILSRYPHQLSGG 172
Cdd:COG1124   75 ------KAFRR-RVQMVFQDPYASLHPRHTVDRILAEPLRIHGLPDREE---RIAELLEQVGLPPS--FLDRYPHQLSGG 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGS 252
Cdd:COG1124  143 QRQRVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELT 222
                        250       260
                 ....*....|....*....|....*
gi 949724212 253 VEQIFHAPQHPYTKALLAAVPQLGA 277
Cdd:COG1124  223 VADLLAGPKHPYTRELLAASLAFER 247
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
12-273 3.12e-81

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 259.25  E-value: 3.12e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFE---------QEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdeMLLRR 82
Cdd:PRK15079   8 LLEVADLKVHFDikdgkqwfwQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEV----AWLGK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  83 rnrqviELGEQSASQMRHVRgADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQ-GASHEEAMVEAKRMLDQVRI-PEaka 160
Cdd:PRK15079  84 ------DLLGMKDDEWRAVR-SDIQMIFQDPLASLNPRMTIGEIIAEPLRTYHpKLSRQEVKDRVKAMMLKVGLlPN--- 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVL 240
Cdd:PRK15079 154 LINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVL 233
                        250       260       270
                 ....*....|....*....|....*....|...
gi 949724212 241 VMYQGEAVETGSVEQIFHAPQHPYTKALLAAVP 273
Cdd:PRK15079 234 VMYLGHAVELGTYDEVYHNPLHPYTKALMSAVP 266
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
31-271 1.24e-76

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 243.43  E-value: 1.24e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLlrrRNRQVIELGeqsasqmrhVRGADIAMIF 110
Cdd:TIGR02770   1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILL---DGRPLLPLS---------IRGRHIATIM 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  111 QEPMTSLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:TIGR02770  69 QNPRTAFNPLFTMGNHAIETLRSL-GKLSKQARALILEALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFL 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLA 270
Cdd:TIGR02770 148 IADEPTTDLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLS 227

                  .
gi 949724212  271 A 271
Cdd:TIGR02770 228 A 228
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
13-293 1.43e-74

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 241.73  E-value: 1.43e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGgEVSCDEMLLRRrnrqvIELGE 92
Cdd:COG4170    4 LDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNW-HVTADRFRWNG-----IDLLK 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASH-----EEAMVEAKRMLDQVRIPEAKAILSRYPH 167
Cdd:COG4170   78 LSPRERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfKWRKKRAIELLHRVGIKDHKDIMNSYPH 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEA 247
Cdd:COG4170  158 ELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQT 237
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 949724212 248 VETGSVEQIFHAPQHPYTKALLAAVPQLgamnGHELPRRFPLISLH 293
Cdd:COG4170  238 VESGPTEQILKSPHHPYTKALLRSMPDF----RQPLPHKSRLNTLP 279
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
311-580 2.44e-73

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 244.43  E-value: 2.44e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ---RGEIIFNGQr 387
Cdd:COG1123    2 TPLLEVRDLSVRYP---------GGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGR- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 388 iDTLAASkLQPLRRDIQFIFQDPYASLDPrQTVGYSILEPLRVHGLLQGDAGsKRVAWLLERVGLlPEHAWRYPHEFSGG 467
Cdd:COG1123   72 -DLLELS-EALRGRRIGMVFQDPMTQLNP-VTVGDQIAEALENLGLSRAEAR-ARVLELLEAVGL-ERRLDRYPHQLSGG 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 468 QRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:COG1123  147 QRQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGP 226
                        250       260       270
                 ....*....|....*....|....*....|...
gi 949724212 548 RRAVFENPQhpytrkLMAAVPVADPSHHRPQRV 580
Cdd:COG1123  227 PEEILAAPQ------ALAAVPRLGAARGRAAPA 253
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
26-286 2.81e-70

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 230.24  E-value: 2.81e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  26 QQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTAlSLMHLIEQ-AGGEvscdemlLRRRNRQVIELGEQSASQMRHvrga 104
Cdd:PRK11308  25 ERLVKALDGVSFTLERGKTLAVVGESGCGKSTLA-RLLTMIETpTGGE-------LYYQGQDLLKADPEAQKLLRQ---- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 105 DIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRI-PEAkaiLSRYPHQLSGGMRQRVMIAMAL 183
Cdd:PRK11308  93 KIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLrPEH---YDRYPHMFSGGQRQRIAIARAL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHP 263
Cdd:PRK11308 170 MLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPRHP 249
                        250       260
                 ....*....|....*....|...
gi 949724212 264 YTKALLAAVPQLgamngHELPRR 286
Cdd:PRK11308 250 YTQALLSATPRL-----NPDDRR 267
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
313-576 2.63e-69

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 225.84  E-value: 2.63e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  313 ILRVRNLVTRFplRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLA 392
Cdd:TIGR02769   2 LLEVRDVTHTY--RTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  393 ASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRI 472
Cdd:TIGR02769  80 RKQRRAFRRDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQRI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  473 CIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEiGTRRAVF 552
Cdd:TIGR02769 160 NIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVE-ECDVAQL 238
                         250       260
                  ....*....|....*....|....
gi 949724212  553 ENPQHPYTRKLMAAVPVADPSHHR 576
Cdd:TIGR02769 239 LSFKHPAGRNLQSAVLPEHPVRRS 262
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
311-571 8.16e-67

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 221.52  E-value: 8.16e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSGIlnrvtreVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ---RGEIIFNGQR 387
Cdd:PRK09473  10 DALLDVKDLRVTFSTPDGD-------VTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGRE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 388 IDTLAASKLQPLR-RDIQFIFQDPYASLDPRQTVGYSILEPLRVH-GLLQGDAGSKRVAwLLERVGLlPEHAWR---YPH 462
Cdd:PRK09473  83 ILNLPEKELNKLRaEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHkGMSKAEAFEESVR-MLDAVKM-PEARKRmkmYPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 463 EFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:PRK09473 161 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRT 240
                        250       260
                 ....*....|....*....|....*....
gi 949724212 543 VEIGTRRAVFENPQHPYTRKLMAAVPVAD 571
Cdd:PRK09473 241 MEYGNARDVFYQPSHPYSIGLLNAVPRLD 269
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
311-566 1.28e-66

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 218.89  E-value: 1.28e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSGILNRvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRidt 390
Cdd:PRK15112   2 ETLLEVRNLSKTFRYRTGWFRR--QTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHP--- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LAASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQ 470
Cdd:PRK15112  77 LHFGDYSYRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQ 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRA 550
Cdd:PRK15112 157 RLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTAD 236
                        250
                 ....*....|....*.
gi 949724212 551 VFENPQHPYTRKLMAA 566
Cdd:PRK15112 237 VLASPLHELTKRLIAG 252
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
312-572 3.33e-65

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 214.94  E-value: 3.33e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPLRSGILNRVTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTL 391
Cdd:PRK10419   2 TLLNVSGLSHHYAHGGLSGKHQHQTV--LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRvHGLLQGDAG-SKRVAWLLERVGLLPEHAWRYPHEFSGGQRQ 470
Cdd:PRK10419  80 NRAQRKAFRRDIQMVFQDSISAVNPRKTVREIIREPLR-HLLSLDKAErLARASEMLRAVDLDDSVLDKRPPQLSGGQLQ 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEigtRRA 550
Cdd:PRK10419 159 RVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVE---TQP 235
                        250       260
                 ....*....|....*....|....
gi 949724212 551 VFENP--QHPYTRKLMAAVPVADP 572
Cdd:PRK10419 236 VGDKLtfSSPAGRVLQNAVLPAFP 259
PhnK COG4107
ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ...
12-272 5.48e-65

ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];


Pssm-ID: 443283 [Multi-domain]  Cd Length: 262  Bit Score: 214.29  E-value: 5.48e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEqaggEVSCDEMLLRRRNRQVIELG 91
Cdd:COG4107    8 LLSVRGLSKRYGPGCGTVVACRDVSFDLYPGEVLGIVGESGSGKS-TLLKCLYFDL----APTSGSVYYRDRDGGPRDLF 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIrLHQGASHEEAM-VEAKRMLDQVRIPeakaiLSR---YPH 167
Cdd:COG4107   83 ALSEAERRRLRRTDWGMVYQNPRDGLRMDVSAGGNIAERL-MAAGERHYGDIrARALEWLERVEIP-----LERiddLPR 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEA 247
Cdd:COG4107  157 TFSGGMQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRTMVMKNGRV 236
                        250       260
                 ....*....|....*....|....*
gi 949724212 248 VETGSVEQIFHAPQHPYTKALLAAV 272
Cdd:COG4107  237 VESGLTDQVLEDPQHPYTQLLVSSV 261
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
313-580 1.34e-63

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 213.02  E-value: 1.34e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQRI 388
Cdd:COG1135    1 MIELENLSKTFPTKGG-------PVTALDDVSLTIEKGEIFGIIGYSGAGKST----LIRCInlleRPTSGSVLVDGVDL 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 389 DTLAASKLQPLRRDIQFIFQDpyASLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQ 468
Cdd:COG1135   70 TALSERELRAARRKIGMIFQH--FNLLSSRTVAENVALPLEIAGVPKAEI-RKRVAELLELVGL-SDKADAYPSQLSGGQ 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 469 RQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTR 548
Cdd:COG1135  146 KQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPV 225
                        250       260       270
                 ....*....|....*....|....*....|..
gi 949724212 549 RAVFENPQHPYTRKLMAAVPVADPSHHRPQRV 580
Cdd:COG1135  226 LDVFANPQSELTRRFLPTVLNDELPEELLARL 257
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
32-271 9.87e-62

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 205.32  E-value: 9.87e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEqAGgevscdemlLRRRNRQVIELGEQSASQmrHVRGADIAMIFQ 111
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILP-AG---------VRQTAGRVLLDGKPVAPC--ALRGRKIATIMQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAkrmLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:PRK10418  87 NPRSAFNPLHTMHTHARETCLALGKPADDATLTAA---LEAVGLENAARVLKLYPFEMSGGMLQRMMIALALLCEAPFII 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLAA 271
Cdd:PRK10418 164 ADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
10-286 1.61e-61

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 205.07  E-value: 1.61e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFE-----QEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRN 84
Cdd:COG4167    2 SALLEVRNLSKTFKyrtglFRRQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYGD 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  85 RQVielgeqsasQMRHVRgadiaMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRI-PEAKAIls 163
Cdd:COG4167   82 YKY---------RCKHIR-----MIFQDPNTSLNPRLNIGQILEEPLRLNTDLTAEEREERIFATLRLVGLlPEHANF-- 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 164 rYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMY 243
Cdd:COG4167  146 -YPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMH 224
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 949724212 244 QGEAVETGSVEQIFHAPQHPYTKALLAAvpQLGAMNGHELPRR 286
Cdd:COG4167  225 QGEVVEYGKTAEVFANPQHEVTKRLIES--HFGEALTADAWRR 265
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
8-270 2.50e-60

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 209.95  E-value: 2.50e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   8 DASDVLAVSNLNIAFEQEQ---QRV----SAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIeQAGGEVSCDEMLL 80
Cdd:PRK15134 271 PASPLLDVEQLQVAFPIRKgilKRTvdhnVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLI-NSQGEIWFDGQPL 349
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  81 RRRNRQvielgeqsasQMRHVRgADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQ---GASHEEAMVeaKRMLDQVRI-P 156
Cdd:PRK15134 350 HNLNRR----------QLLPVR-HRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHQptlSAAQREQQV--IAVMEEVGLdP 416
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 157 EAKailSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIA 236
Cdd:PRK15134 417 ETR---HRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALC 493
                        250       260       270
                 ....*....|....*....|....*....|....
gi 949724212 237 DRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLA 270
Cdd:PRK15134 494 HQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLA 527
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
312-572 1.66e-58

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 204.94  E-value: 1.66e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFplRSGilnRVTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRL-----VESQRGEIIFNGQ 386
Cdd:PRK15134   4 PLLAIENLSVAF--RQQ---QTVRTV--VNDVSLQIEAGETLALVGESGSGKSVTALSILRLlpsppVVYPSGDIRFHGE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDTLAASKLQPLRRD-IQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLlpEHAWR----YP 461
Cdd:PRK15134  77 SLLHASEQTLRGVRGNkIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGI--RQAAKrltdYP 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 HEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQ 541
Cdd:PRK15134 155 HQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGR 234
                        250       260       270
                 ....*....|....*....|....*....|.
gi 949724212 542 IVEIGTRRAVFENPQHPYTRKLMAAVPVADP 572
Cdd:PRK15134 235 CVEQNRAATLFSAPTHPYTQKLLNSEPSGDP 265
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
339-568 3.76e-58

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 198.43  E-value: 3.76e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE----SQRGEIIFNGQRIDTLAASKLQPL-RRDIQFIFQDPYAS 413
Cdd:PRK11022  22 AVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRISEKERRNLvGAEVAMIFQDPMTS 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDPRQTVGYSILEPLRVHgllQGdaGSK-----RVAWLLERVGLlPEHAWR---YPHEFSGGQRQRICIARALALNPKVI 485
Cdd:PRK11022 102 LNPCYTVGFQIMEAIKVH---QG--GNKktrrqRAIDLLNQVGI-PDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLL 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 486 IADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMA 565
Cdd:PRK11022 176 IADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPYTQALLR 255

                 ...
gi 949724212 566 AVP 568
Cdd:PRK11022 256 ALP 258
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
310-561 1.61e-57

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 193.66  E-value: 1.61e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 310 GEPILRVRNLVTRFplrsGilnrvTREVHavENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRID 389
Cdd:COG1127    2 SEPMIEVRNLTKSF----G-----DRVVL--DGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDIT 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 390 TLAASKLQPLRRDIQFIFQDP--YASLdprqTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGlLPEHAWRYPHEFSGG 467
Cdd:COG1127   71 GLSEKELYELRRRIGMLFQGGalFDSL----TVFENVAFPLREHTDLSEAEIRELVLEKLELVG-LPGAADKMPSELSGG 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 468 QRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:COG1127  146 MRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGT 225
                        250
                 ....*....|....
gi 949724212 548 RRAVFENPqHPYTR 561
Cdd:COG1127  226 PEELLASD-DPWVR 238
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
312-559 1.96e-57

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 197.24  E-value: 1.96e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTL 391
Cdd:COG3842    4 PALELENVSKRYG-----------DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGL 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AASKlqplrRDIQFIFQDpYAsLDP----RQTVGYsilePLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGG 467
Cdd:COG3842   73 PPEK-----RNVGMVFQD-YA-LFPhltvAENVAF----GLRMRGVPKAEI-RARVAELLELVGL-EGLADRYPHQLSGG 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 468 QRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHD----MAvverISHRVAVMYLGQIV 543
Cdd:COG3842  140 QQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDqeeaLA----LADRIAVMNDGRIE 215
                        250
                 ....*....|....*.
gi 949724212 544 EIGTRRAVFENPQHPY 559
Cdd:COG3842  216 QVGTPEEIYERPATRF 231
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
335-556 8.25e-57

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 191.64  E-value: 8.25e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 335 REVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLVE----SQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDp 410
Cdd:cd03258   16 GKVTALKDVSLSVPKGEIFGIIGRSGAGKST----LIRCINglerPTSGSVLVDGTDLTLLSGKELRKARRRIGMIFQH- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 411 YASLDPRqTVGYSILEPLRVHGLLQGDAGsKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:cd03258   91 FNLLSSR-TVFENVALPLEIAGVPKAEIE-ERVLELLELVGL-EDKADAYPAQLSGGQKQRVGIARALANNPKVLLCDEA 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 491 VSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:cd03258  168 TSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
334-567 2.06e-55

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 191.55  E-value: 2.06e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 334 TREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQdpYAS 413
Cdd:PRK11153  15 GRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKARRQIGMIFQ--HFN 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSA 493
Cdd:PRK11153  93 LLSSRTVFDNVALPLELAGTPKAEI-KARVTELLELVGL-SDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSA 170
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 494 LDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAV 567
Cdd:PRK11153 171 LDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTREFIQST 244
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
314-561 4.08e-53

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 181.55  E-value: 4.08e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrsGilnrvTREVHavENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03261    1 IELRGLTKSF----G-----GRTVL--KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSE 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDP--YASLDPRQTVGYsilePLRVHGLLQGDAGSKRVAWLLERVGLLPEHAwRYPHEFSGGQRQR 471
Cdd:cd03261   70 AELYRLRRRMGMLFQSGalFDSLTVFENVAF----PLREHTRLSEEEIREIVLEKLEAVGLRGAED-LYPAELSGGMKKR 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:cd03261  145 VALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
                        250
                 ....*....|
gi 949724212 552 FeNPQHPYTR 561
Cdd:cd03261  225 R-ASDDPLVR 233
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
12-325 8.41e-53

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 184.24  E-value: 8.41e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHlIEQAGGEVSCDEMllrRRNRqvIELG 91
Cdd:PRK15093   3 LLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICG-VTKDNWRVTADRM---RFDD--IDLL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIR--LHQGASHEEAMVEAKR---MLDQVRIPEAKAILSRYP 166
Cdd:PRK15093  77 RLSPRERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPgwTYKGRWWQRFGWRKRRaieLLHRVGIKDHKDAMRSFP 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:PRK15093 157 YELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQ 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 247 AVETGSVEQIFHAPQHPYTKALLAAVPQLGAMNGHE-----LPRRFPLISlHDP--SHVEPQT--EQDTVVEGEPILRVR 317
Cdd:PRK15093 237 TVETAPSKELVTTPHHPYTQALIRAIPDFGSAMPHKsrlntLPGAIPLLE-HLPigCRLGPRCpyAQRECIETPRLTGAK 315
                        330
                 ....*....|
gi 949724212 318 N--LVTRFPL 325
Cdd:PRK15093 316 NhlYACHFPL 325
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
29-545 1.21e-52

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 188.30  E-value: 1.21e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvTalsLMHLI---EQA-GGEVSCDEMLLRRRN-RQVIELGeqsasqmrhvrg 103
Cdd:COG1129   17 VKALDGVSLELRPGEVHALLGENGAGKS-T---LMKILsgvYQPdSGEILLDGEPVRFRSpRDAQAAG------------ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 104 adIAMIFQEPmtSLNPVFTVgeqiAESIRLHQ-----GASHEEAMV-EAKRMLDQVRIPE-AKAILSRyphqLSGGMRQR 176
Cdd:COG1129   81 --IAIIHQEL--NLVPNLSV----AENIFLGReprrgGLIDWRAMRrRARELLARLGLDIdPDTPVGD----LSVAQQQL 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:COG1129  149 VEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 257 fhapqhpyTKALLAAvpqlgAMNGHELPRRFPlislhdPSHVEPqteqdtvveGEPILRVRNLVTRfplrsgilnrvtre 336
Cdd:COG1129  228 --------TEDELVR-----LMVGRELEDLFP------KRAAAP---------GEVVLEVEGLSVG-------------- 265
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 337 vHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTlaASKLQPLRRDIQF---------IF 407
Cdd:COG1129  266 -GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRI--RSPRDAIRAGIAYvpedrkgegLV 342
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 408 QDpyasLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIA 487
Cdd:COG1129  343 LD----LSIRENITLASLDRLSRGGLLDRRRERALAEEYIKRLRIKTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLIL 418
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 488 DESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEI 545
Cdd:COG1129  419 DEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDRILVMREGRIVGE 475
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
314-542 1.46e-52

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 179.61  E-value: 1.46e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPLRSgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQRID 389
Cdd:cd03255    1 IELKNLSKTYGGGG-------EKVQALKGVSLSIEKGEFVAIVGPSGSGKST----LLNILggldRPTSGEVRVDGTDIS 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 390 TLAASKLQPLRRD-IQFIFQDPYasLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQ 468
Cdd:cd03255   70 KLSEKELAAFRRRhIGFVFQSFN--LLPDLTALENVELPLLLAGVPKKER-RERAEELLERVGL-GDRLNHYPSELSGGQ 145
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 469 RQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQI 542
Cdd:cd03255  146 QQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
311-544 2.49e-52

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 179.47  E-value: 2.49e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQ 386
Cdd:COG1136    2 SPLLELRNLTKSYGTGEG-------EVTALRGVSLSIEAGEFVAIVGPSGSGKST----LLNILggldRPTSGEVLIDGQ 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDTLAASKLQPLRRD-IQFIFQDPYasLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFS 465
Cdd:COG1136   71 DISSLSERELARLRRRhIGFVFQFFN--LLPELTALENVALPLLLAGVSRKER-RERARELLERVGL-GDRLDHRPSQLS 146
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 466 GGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQIVE 544
Cdd:COG1136  147 GGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAAR-ADRVIRLRDGRIVS 224
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
13-546 2.57e-52

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 188.09  E-value: 2.57e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   13 LAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSVtalsLMHLI------EQAGGEV-----SCDEMLLR 81
Cdd:TIGR03269   1 IEVKNLTKKFDG----KEVLKNISFTIEEGEVLGILGRSGAGKSV----LMHVLrgmdqyEPTSGRIiyhvaLCEKCGYV 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   82 RR---------------NRQVIELGEQSASQMRHVRgADIAMIFQEPMtSLNPVFTVGEQIAESirLHQ-GASHEEAMVE 145
Cdd:TIGR03269  73 ERpskvgepcpvcggtlEPEEVDFWNLSDKLRRRIR-KRIAIMLQRTF-ALYGDDTVLDNVLEA--LEEiGYEGKEAVGR 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  146 AKRMLDQVRIPEAKAILSRyphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFI 225
Cdd:TIGR03269 149 AVDLIEMVQLSHRITHIAR---DLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  226 THDMGVVADIADRVLVMYQGEAVETGSVEQIfhapqhpyTKALLAAVPQLgamnghelprrfplislhdpshvepqtEQD 305
Cdd:TIGR03269 226 SHWPEVIEDLSDKAIWLENGEIKEEGTPDEV--------VAVFMEGVSEV---------------------------EKE 270
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  306 TVVE-GEPILRVRNLVTRF-PLRSGIlnrvtreVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIF 383
Cdd:TIGR03269 271 CEVEvGEPIIKVRNVSKRYiSVDRGV-------VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV 343
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  384 ngqRI--DTLAASKLQPLRRD-----IQFIFQDpyASLDPRQTVGYSILEPLRVHglLQGDAGSKRVAWLLERVGLLPEH 456
Cdd:TIGR03269 344 ---RVgdEWVDMTKPGPDGRGrakryIGILHQE--YDLYPHRTVLDNLTEAIGLE--LPDELARMKAVITLKMVGFDEEK 416
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  457 AW----RYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISH 532
Cdd:TIGR03269 417 AEeildKYPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCD 496
                         570
                  ....*....|....
gi 949724212  533 RVAVMYLGQIVEIG 546
Cdd:TIGR03269 497 RAALMRDGKIVKIG 510
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
29-551 7.40e-52

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 186.00  E-value: 7.40e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI---EQA-GGEVSCDEMLLRRRN-RQVIELGeqsasqmrhvrg 103
Cdd:COG3845   18 VVANDDVSLTVRPGEIHALLGENGAGKS----TLMKILyglYQPdSGEILIDGKPVRIRSpRDAIALG------------ 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 104 adIAMIFQEPMtsLNPVFTVgeqiAESIRLhqGASHEEAMVEAKRMLDQvripEAKAILSRYP---------HQLSGGMR 174
Cdd:COG3845   82 --IGMVHQHFM--LVPNLTV----AENIVL--GLEPTKGGRLDRKAARA----RIRELSERYGldvdpdakvEDLSVGEQ 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 175 QRVMIAMALSCRPAVLIADEPTTALdvTIQaQILQLIKVLQQ--DMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGS 252
Cdd:COG3845  148 QRVEILKALYRGARILILDEPTAVL--TPQ-EADELFEILRRlaAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVD 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 253 VEQIfhapqhpyTKALLAAvpqlgAMNGHElprrfplislhdpshVEPQTEQDTVVEGEPILRVRNLVTRFPlrsgilnr 332
Cdd:COG3845  225 TAET--------SEEELAE-----LMVGRE---------------VLLRVEKAPAEPGEVVLEVENLSVRDD-------- 268
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 333 vtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqpLRRDIQFIFQDpya 412
Cdd:COG3845  269 --RGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRER--RRLGVAYIPED--- 341
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 sldpRQTVG----YSILE----------PLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARAL 478
Cdd:COG3845  342 ----RLGRGlvpdMSVAEnlilgryrrpPFSRGGFLDRKAIRAFAEELIEEFDVRTPGPDTPARSLSGGNQQKVILAREL 417
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 479 ALNPKVIIADESVSALDVS----IRGQIINLmldlqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:COG3845  418 SRDPKLLIAAQPTRGLDVGaiefIHQRLLEL-----RDAGAAVLLISEDLDEILALSDRIAVMYEGRIVGEVPAAEA 489
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
15-274 7.47e-52

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 181.81  E-value: 7.47e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDEmllrrrnrqvIELGEQ 93
Cdd:COG1135    4 LENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKS-TLIRCINLLERPtSGSVLVDG----------VDLTAL 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 SASQMRHVRgADIAMIFQEP--MTSLnpvfTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIpEAKAilSRYPHQLSG 171
Cdd:COG1135   73 SERELRAAR-RKIGMIFQHFnlLSSR----TVAENVALPLEI-AGVPKAEIRKRVAELLELVGL-SDKA--DAYPSQLSG 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:COG1135  144 GQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQG 223
                        250       260
                 ....*....|....*....|...
gi 949724212 252 SVEQIFHAPQHPYTKALLAAVPQ 274
Cdd:COG1135  224 PVLDVFANPQSELTRRFLPTVLN 246
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
313-567 1.01e-51

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 177.88  E-value: 1.01e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFplrsGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdTLA 392
Cdd:COG1126    1 MIEIENLHKSF----G-------DLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDS 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLQPLRRDIQFIFQDpyASLDPRQTVgysiLE-----PLRVHGLLQGDAgSKRVAWLLERVGLLpEHAWRYPHEFSGG 467
Cdd:COG1126   69 KKDINKLRRKVGMVFQQ--FNLFPHLTV----LEnvtlaPIKVKKMSKAEA-EERAMELLERVGLA-DKADAYPAQLSGG 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 468 QRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:COG1126  141 QQQRVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGP 219
                        250       260
                 ....*....|....*....|
gi 949724212 548 RRAVFENPQHPYTRKLMAAV 567
Cdd:COG1126  220 PEEFFENPQHERTRAFLSKV 239
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
330-546 1.45e-51

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 176.94  E-value: 1.45e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 330 LNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaaSKLQPLRRDIQFIFQD 409
Cdd:cd03259    6 LSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV-----TGVPPERRNIGMVFQD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 410 PyaSLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADE 489
Cdd:cd03259   81 Y--ALFPHLTVAENIAFGLKLRGVPKAEI-RARVRELLELVGL-EGLLNRYPHELSGGQQQRVALARALAREPSLLLLDE 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 490 SVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03259  157 PLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
12-272 2.01e-50

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 174.41  E-value: 2.01e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEVSCDEMLLRRRNRQViel 90
Cdd:COG1126    1 MIEIENLHKSFGDLE----VLKGISLDVEKGEVVVIIGPSGSGKS-TLLrCINLLEEPDSGTITVDGEDLTDSKKDI--- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 geqsasqmRHVRgADIAMIFQepmtSLN--PVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEaKAilSRYPHQ 168
Cdd:COG1126   73 --------NKLR-RKVGMVFQ----QFNlfPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLAD-KA--DAYPAQ 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVL-QQDMSMgvIFITHDMGVVADIADRVLVMYQGEA 247
Cdd:COG1126  137 LSGGQQQRVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLaKEGMTM--VVVTHEMGFAREVADRVVFMDGGRI 214
                        250       260
                 ....*....|....*....|....*
gi 949724212 248 VETGSVEQIFHAPQHPYTKALLAAV 272
Cdd:COG1126  215 VEEGPPEEFFENPQHERTRAFLSKV 239
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
339-572 6.80e-50

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 174.37  E-value: 6.80e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRR-DIQFIFQDpyASLDPR 417
Cdd:cd03294   39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRkKISMVFQS--FALLPH 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILEPLRVHGllQGDAGSKRVAW-LLERVGLlpeHAW--RYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:cd03294  117 RTVLENVAFGLEVQG--VPRAEREERAAeALELVGL---EGWehKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSAL 191
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 495 DVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVPVADP 572
Cdd:cd03294  192 DPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRGVDRAKV 269
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
314-537 2.49e-49

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 171.12  E-value: 2.49e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaa 393
Cdd:cd03293    1 LEVRNVSKTYGGGGG-------AVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPV----- 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 sklQPLRRDIQFIFQDPyaSLDPRQTVGYSILEPLRVHGLLQGDAGsKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRIC 473
Cdd:cd03293   69 ---TGPGPDRGYVFQQD--ALLPWLTVLDNVALGLELQGVPKAEAR-ERAEELLELVGLS-GFENAYPHQLSGGMRQRVA 141
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 474 IARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDM--AVveRISHRVAVM 537
Cdd:cd03293  142 LARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIdeAV--FLADRVVVL 205
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
339-561 8.28e-49

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 170.56  E-value: 8.28e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqplRRDIQFIFQDpyASLDPRQ 418
Cdd:cd03295   16 AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVEL---RRKIGYVIQQ--IGLFPHM 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLPEH-AWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:cd03295   91 TVEENIALVPKLLKWPKEKI-RERADELLALVGLDPAEfADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPI 169
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 498 IRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTR 561
Cdd:cd03295  170 TRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVA 233
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
13-246 1.14e-48

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 169.21  E-value: 1.14e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDEmllrrrnrqvIELG 91
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKS-TLLNILGGLDRPtSGEVRVDG----------TDIS 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADIAMIFQEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSG 171
Cdd:cd03255   70 KLSEKELAAFRRRHIGFVFQSF--NLLPDLTALENVELPLLL-AGVPKKERRERAEELLERVGLGD---RLNHYPSELSG 143
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMgVVADIADRVLVMYQGE 246
Cdd:cd03255  144 GQQQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDP-ELAEYADRIIELRDGK 217
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
311-545 4.41e-48

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 169.11  E-value: 4.41e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQ 386
Cdd:COG1116    5 APALELRGVSKRFPTGGG-------GVTALDDVSLTVAAGEFVALVGPSGCGKST----LLRLIagleKPTSGEVLVDGK 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDtlaasklqPLRRDIQFIFQDPyaSLDPRQTVGYSILEPLRVHGLLQGDAGsKRVAWLLERVGLLpEHAWRYPHEFSG 466
Cdd:COG1116   74 PVT--------GPGPDRGVVFQEP--ALLPWLTVLDNVALGLELRGVPKAERR-ERARELLELVGLA-GFEDAYPHQLSG 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 467 GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDM--AVveRISHRVAVM--YLGQI 542
Cdd:COG1116  142 GMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVdeAV--FLADRVVVLsaRPGRI 219

                 ...
gi 949724212 543 VEI 545
Cdd:COG1116  220 VEE 222
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
338-556 5.86e-48

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 167.80  E-value: 5.86e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaaSKLQPLRRDIQFIFQDpYAsLDPR 417
Cdd:cd03300   14 VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI-----TNLPPHKRPVNTVFQN-YA-LFPH 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILEPLRVHGLLQGDAGsKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:cd03300   87 LTVFENIAFGLRLKKLPKAEIK-ERVAEALDLVQLE-GYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLK 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 498 IRGQI-INLMlDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:cd03300  165 LRKDMqLELK-RLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPA 223
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
15-261 7.70e-48

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 167.37  E-value: 7.70e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDEMllrrrnrqviELGEQ 93
Cdd:cd03258    4 LKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKS-TLIRCINGLERpTSGSVLVDGT----------DLTLL 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 SASQMRHVRgADIAMIFQE--PMTSLnpvfTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIpEAKAilSRYPHQLSG 171
Cdd:cd03258   73 SGKELRKAR-RRIGMIFQHfnLLSSR----TVFENVALPLEIA-GVPKAEIEERVLELLELVGL-EDKA--DAYPAQLSG 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03258  144 GQKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEG 223
                        250
                 ....*....|
gi 949724212 252 SVEQIFHAPQ 261
Cdd:cd03258  224 TVEEVFANPQ 233
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
10-249 1.40e-47

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 166.37  E-value: 1.40e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDEmllrrrnrqvI 88
Cdd:COG1136    2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKS-TLLNILGGLDRPtSGEVLIDG----------Q 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELGEQSASQMRHVRGADIAMIFQEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQ 168
Cdd:COG1136   71 DISSLSERELARLRRRHIGFVFQFF--NLLPELTALENVALPLLL-AGVSRKERRERARELLERVGLGD---RLDHRPSQ 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMgVVADIADRVLVMYQGEAV 248
Cdd:COG1136  145 LSGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRIV 223

                 .
gi 949724212 249 E 249
Cdd:COG1136  224 S 224
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
312-543 2.26e-47

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 166.77  E-value: 2.26e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPlrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTL 391
Cdd:COG3638    1 PMLELRNLSKRYP----------GGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTAL 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AASKLQPLRRDIQFIFQDPYasLDPRQTV---------GYsileplrvHGLLQGDAGS------KRVAWLLERVGLLpEH 456
Cdd:COG3638   71 RGRALRRLRRRIGMIFQQFN--LVPRLSVltnvlagrlGR--------TSTWRSLLGLfppedrERALEALERVGLA-DK 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 457 AWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAV 536
Cdd:COG3638  140 AYQRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIG 219

                 ....*..
gi 949724212 537 MYLGQIV 543
Cdd:COG3638  220 LRDGRVV 226
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
31-274 3.47e-47

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 166.64  E-value: 3.47e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLM--HLIEQAGgevscdEMLLRRRNRQVIELGEQSASQMRHVRGADIAM 108
Cdd:PRK11701  21 GCRDVSFDLYPGEVLGIVGESGSGKT-TLLNALsaRLAPDAG------EVHYRMRDGQLRDLYALSEAERRRLLRTEWGF 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPMTSLNPVFTVGEQIAEsiRLH-QGASH-EEAMVEAKRMLDQVRIPEAKaiLSRYPHQLSGGMRQRVMIAMALSCR 186
Cdd:PRK11701  94 VHQHPRDGLRMQVSAGGNIGE--RLMaVGARHyGDIRATAGDWLERVEIDAAR--IDDLPTTFSGGMQQRLQIARNLVTH 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 187 PAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTK 266
Cdd:PRK11701 170 PRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQVLDDPQHPYTQ 249

                 ....*...
gi 949724212 267 ALLAAVPQ 274
Cdd:PRK11701 250 LLVSSVLQ 257
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
330-551 4.81e-47

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 165.05  E-value: 4.81e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 330 LNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQR-----GEIIFNGQRIDTLAASKLQpLRRDIQ 404
Cdd:cd03260    6 LNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPgapdeGEVLLDGKDIYDLDVDVLE-LRRRVG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 405 FIFQDPYasldP-RQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWR-YPHEFSGGQRQRICIARALALNP 482
Cdd:cd03260   85 MVFQKPN----PfPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRlHALGLSGGQQQRLCLARALANEP 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 483 KVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:cd03260  161 EVLLLDEPTSALDPISTAKIEELIAELKKEYTI--VIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
314-556 9.99e-47

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 164.43  E-value: 9.99e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridTLAA 393
Cdd:COG1122    1 IELENLSFSYP----------GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGK---DITK 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDPyaslDpRQTVGYSILE----PLRVHGLLQGDAgSKRVAWLLERVGLLpEHAWRYPHEFSGGQR 469
Cdd:COG1122   68 KNLRELRRKVGLVFQNP----D-DQLFAPTVEEdvafGPENLGLPREEI-RERVEEALELVGLE-HLADRPPHELSGGQK 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:COG1122  141 QRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPR 219

                 ....*..
gi 949724212 550 AVFENPQ 556
Cdd:COG1122  220 EVFSDYE 226
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
312-568 7.58e-46

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 165.08  E-value: 7.58e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPLRSGIlnrvtreVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRL------VESQRgeIIFNG 385
Cdd:COG4170    2 PLLDIRNLTIEIDTPQGR-------VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGItkdnwhVTADR--FRWNG 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 386 qrIDTLAAS---KLQPLRRDIQFIFQDPYASLDPRQTVGYSILE-----PLRVHGLLQGDAGSKRVAWLLERVGLL-PEH 456
Cdd:COG4170   73 --IDLLKLSpreRRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEaipswTFKGKWWQRFKWRKKRAIELLHRVGIKdHKD 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 457 AWR-YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVA 535
Cdd:COG4170  151 IMNsYPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTIT 230
                        250       260       270
                 ....*....|....*....|....*....|...
gi 949724212 536 VMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVP 568
Cdd:COG4170  231 VLYCGQTVESGPTEQILKSPHHPYTKALLRSMP 263
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
311-567 1.41e-45

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 162.02  E-value: 1.41e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRsgilnrvtrevHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIF---NGQR 387
Cdd:PRK11701   4 QPLLSVRGLTKLYGPR-----------KGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYrmrDGQL 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 388 IDTLAASKLQP---LRRDIQFIFQDPYASLDPRQTVGYSILEPL-----RVHGLLQGDAGSkrvaWLlERVGLLPEHAWR 459
Cdd:PRK11701  73 RDLYALSEAERrrlLRTEWGFVHQHPRDGLRMQVSAGGNIGERLmavgaRHYGDIRATAGD----WL-ERVEIDAARIDD 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 460 YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYL 539
Cdd:PRK11701 148 LPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQ 227
                        250       260
                 ....*....|....*....|....*...
gi 949724212 540 GQIVEIGTRRAVFENPQHPYTRKLMAAV 567
Cdd:PRK11701 228 GRVVESGLTDQVLDDPQHPYTQLLVSSV 255
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
314-560 1.54e-45

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 164.93  E-value: 1.54e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLR----LVESQRGEIIFNGQRID 389
Cdd:COG1118    3 IEVRNISKRFG-----------SFTLLDDVSLEIASGELVALLGPSGSGKTT----LLRiiagLETPDSGRIVLNGRDLF 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 390 TlaasKLQPLRRDIQFIFQDpYAsLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQR 469
Cdd:COG1118   68 T----NLPPRERRVGFVFQH-YA-LFPHMTVAENIAFGLRVRPPSKAEI-RARVEELLELVQL-EGLADRYPSQLSGGQR 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:COG1118  140 QRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPD 219
                        250
                 ....*....|.
gi 949724212 550 AVFENPQHPYT 560
Cdd:COG1118  220 EVYDRPATPFV 230
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
337-548 1.55e-45

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 160.99  E-value: 1.55e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 337 VHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDpyASLDP 416
Cdd:COG2884   15 REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYLRRRIGVVFQD--FRLLP 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYSILEPLRVHGLLQGDAGsKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:COG2884   93 DRTVYENVALPLRVTGKSRKEIR-RRVREVLDLVGLS-DKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDP 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 949724212 497 SIRGQIINLMLDLQReLGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTR 548
Cdd:COG2884  171 ETSWEIMELLEEINR-RGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEAR 221
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
12-271 2.24e-45

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 161.88  E-value: 2.24e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQE-----QQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLrrrnrq 86
Cdd:PRK15112   4 LLEVRNLSKTFRYRtgwfrRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPL------ 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  87 viELGEQSASQMRhvrgadIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAilSRYP 166
Cdd:PRK15112  78 --HFGDYSYRSQR------IRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPDHA--SYYP 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:PRK15112 148 HMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGE 227
                        250       260
                 ....*....|....*....|....*
gi 949724212 247 AVETGSVEQIFHAPQHPYTKALLAA 271
Cdd:PRK15112 228 VVERGSTADVLASPLHELTKRLIAG 252
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
314-541 2.64e-45

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 158.50  E-value: 2.64e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03229    1 LELKNVSKRYG-----------QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLED 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 sKLQPLRRDIQFIFQDPyaSLDPRQTVGYSILEPLrvhgllqgdagskrvawllervgllpehawryphefSGGQRQRIC 473
Cdd:cd03229   70 -ELPPLRRRIGMVFQDF--ALFPHLTVLENIALGL------------------------------------SGGQQQRVA 110
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 474 IARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQ 541
Cdd:cd03229  111 LARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
16-316 3.81e-45

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 163.43  E-value: 3.81e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  16 SNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDEmllrrrnrqvIELGEQS 94
Cdd:PRK11153   5 KNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKS-TLIRCINLLERpTSGRVLVDG----------QDLTALS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  95 ASQMRHVRgADIAMIFQEpmtslnpvF------TVGEQIAESIRLhQGASHEEamVEAK--RMLDQVRIpEAKAilSRYP 166
Cdd:PRK11153  74 EKELRKAR-RQIGMIFQH--------FnllssrTVFDNVALPLEL-AGTPKAE--IKARvtELLELVGL-SDKA--DRYP 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:PRK11153 139 AQLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGR 218
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 247 AVETGSVEQIFHAPQHPYTKALLAAVpqlgamnghelprrfplISLHDPSHVEPQTEQDTVVEGEPILRV 316
Cdd:PRK11153 219 LVEQGTVSEVFSHPKHPLTREFIQST-----------------LHLDLPEDYLARLQAEPTTGSGPLLRL 271
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
13-261 7.13e-45

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 159.42  E-value: 7.13e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRqvielge 92
Cdd:COG1122    1 IELENLSFSYPGGTP---ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNL------- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 qsasqmRHVRgADIAMIFQEPMTSL-NPvfTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSG 171
Cdd:COG1122   71 ------RELR-RKVGLVFQNPDDQLfAP--TVEEDVAFGPE-NLGLPREEIRERVEEALELVGLEH---LADRPPHELSG 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:COG1122  138 GQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIVADG 216
                        250
                 ....*....|
gi 949724212 252 SVEQIFHAPQ 261
Cdd:COG1122  217 TPREVFSDYE 226
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
314-551 1.52e-44

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 158.69  E-value: 1.52e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:COG1131    1 IEVRGLTKRY-----------GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPA 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SklqpLRRDIQFIFQDPyaSLDPRQTVGysilEPLRVHGLLQGDAGS---KRVAWLLERVGLlPEHAWRYPHEFSGGQRQ 470
Cdd:COG1131   70 E----VRRRIGYVPQEP--ALYPDLTVR----ENLRFFARLYGLPRKearERIDELLELFGL-TDAADRKVGTLSGGMKQ 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRA 550
Cdd:COG1131  139 RLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDE 217

                 .
gi 949724212 551 V 551
Cdd:COG1131  218 L 218
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
27-272 2.92e-44

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 159.08  E-value: 2.92e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  27 QRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRqvielgeqsaSQMRHVRGaDI 106
Cdd:PRK10419  23 QHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNR----------AQRKAFRR-DI 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 107 AMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQRVMIAMALSCR 186
Cdd:PRK10419  92 QMVFQDSISAVNPRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDDS--VLDKRPPQLSGGQLQRVCLARALAVE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 187 PAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHApQHPYTK 266
Cdd:PRK10419 170 PKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGDKLTF-SSPAGR 248

                 ....*.
gi 949724212 267 ALLAAV 272
Cdd:PRK10419 249 VLQNAV 254
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
314-543 3.94e-43

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 155.03  E-value: 3.94e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03256    1 IEVENLSKTYP----------NGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKG 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDPyaSLDPRQTVGYSILEP-LRVHGLLQGDAGS-----KRVAW-LLERVGLLpEHAWRYPHEFSG 466
Cdd:cd03256   71 KALRQLRRQIGMIFQQF--NLIERLSVLENVLSGrLGRRSTWRSLFGLfpkeeKQRALaALERVGLL-DKAYQRADQLSG 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 467 GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:cd03256  148 GQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIV 224
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
306-561 6.74e-43

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 154.81  E-value: 6.74e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 306 TVVEGEPILRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLR---LVESQR--GE 380
Cdd:COG1117    4 PASTLEPKIEVRNLNVYY-----------GDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRmndLIPGARveGE 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 381 IIFNGQRIdtlAASKLQP--LRRDIQFIFQ--DPYASldprqtvgySILE----PLRVHGLLQGDAGSKRVAWLLERVGL 452
Cdd:COG1117   73 ILLDGEDI---YDPDVDVveLRRRVGMVFQkpNPFPK---------SIYDnvayGLRLHGIKSKSELDEIVEESLRKAAL 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 453 LPE-----HawRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVV 527
Cdd:COG1117  141 WDEvkdrlK--KSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTI--VIVTHNMQQA 216
                        250       260       270
                 ....*....|....*....|....*....|....
gi 949724212 528 ERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTR 561
Cdd:COG1117  217 ARVSDYTAFFYLGELVEFGPTEQIFTNPKDKRTE 250
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
13-242 3.30e-42

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 151.86  E-value: 3.30e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDEMLLRRRNRqvielg 91
Cdd:cd03293    1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKS-TLLRIIAgLERPTSGEVLVDGEPVTGPGP------ 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 eqsasqmrhvrgaDIAMIFQEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAkaiLSRYPHQLSG 171
Cdd:cd03293   74 -------------DRGYVFQQD--ALLPWLTVLDNVALGLEL-QGVPKAEARERAEELLELVGLSGF---ENAYPHQLSG 134
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVM 242
Cdd:cd03293  135 GMRQRVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
12-272 3.39e-42

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 152.68  E-value: 3.39e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALSLM--HLIEQAGgevscdEMLLRRRNRQVIE 89
Cdd:TIGR02323   3 LLQVSGLSKSYGGGK----GCRDVSFDLYPGEVLGIVGESGSGKS-TLLGCLagRLAPDHG------TATYIMRSGAELE 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   90 LGEQSASQMRHVRGADIAMIFQEPMTSLNPVFTVGEQIAESIrLHQGASHEEAM-VEAKRMLDQVRIPEAKaiLSRYPHQ 168
Cdd:TIGR02323  72 LYQLSEAERRRLMRTEWGFVHQNPRDGLRMRVSAGANIGERL-MAIGARHYGNIrATAQDWLEEVEIDPTR--IDDLPRA 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAV 248
Cdd:TIGR02323 149 FSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVV 228
                         250       260
                  ....*....|....*....|....
gi 949724212  249 ETGSVEQIFHAPQHPYTKALLAAV 272
Cdd:TIGR02323 229 ESGLTDQVLDDPQHPYTQLLVSSI 252
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
12-269 5.02e-42

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 151.67  E-value: 5.02e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQeqQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELG 91
Cdd:COG1127    5 MIEVRNLTKSFGD--RVV--LDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDG----------QDIT 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRgADIAMIFQEP--MTSLnpvfTVGEQIAESIRLHQGASHEEA--MVEAKrmLDQVRIPEAKailSRYPH 167
Cdd:COG1127   71 GLSEKELYELR-RRIGMLFQGGalFDSL----TVFENVAFPLREHTDLSEAEIreLVLEK--LELVGLPGAA---DKMPS 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEA 247
Cdd:COG1127  141 ELSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKI 220
                        250       260
                 ....*....|....*....|..
gi 949724212 248 VETGSVEQIFHAPqHPYTKALL 269
Cdd:COG1127  221 IAEGTPEELLASD-DPWVRQFL 241
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
338-542 1.46e-41

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 149.60  E-value: 1.46e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdTLAASKLQPLRRDIQFIFQDpyASLDPR 417
Cdd:cd03262   14 HVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL-TDDKKNINELRQKVGMVFQQ--FNLFPH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILE-PLRVHGLLQGDAGsKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:cd03262   91 LTVLENITLaPIKVKGMSKAEAE-ERALELLEKVGLA-DKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDP 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 949724212 497 SIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:cd03262  169 ELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDGRI 213
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
19-246 1.56e-41

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 149.54  E-value: 1.56e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRrrnrqvielgeqsASQM 98
Cdd:cd03225    4 NLSFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLT-------------KLSL 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHVRGaDIAMIFQEPMTSL-NPvfTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRV 177
Cdd:cd03225   71 KELRR-KVGLVFQNPDDQFfGP--TVEEEVAFGLE-NLGLPEEEIEERVEEALELVGL---EGLRDRSPFTLSGGQKQRV 143
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 178 MIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMsMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03225  144 AIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEG-KTIIIVTHDLDLLLELADRVIVLEDGK 211
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
31-257 1.64e-41

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 151.45  E-value: 1.64e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDEMLLRRRNRQvielgeqsasQMRHVRgADIAMI 109
Cdd:TIGR04521  20 ALDDVSLTIEDGEFVAIIGHTGSGKS-TLIQHLNgLLKPTSGTVTIDGRDITAKKKK----------KLKDLR-KKVGLV 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  110 FQEPMTSLnpvF--TVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:TIGR04521  88 FQFPEHQL---FeeTVYKDIAFGPK-NLGLSEEEAEERVKEALELVGLDEE--YLERSPFELSGGQMRRVAIAGVLAMEP 161
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  188 AVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:TIGR04521 162 EVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVF 231
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
28-256 3.47e-41

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 149.44  E-value: 3.47e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  28 RVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCdemllrrrnrqvieLGEQSASQMRHVRgADIA 107
Cdd:COG1131   12 DKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRV--------------LGEDVARDPAEVR-RRIG 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEPmtSLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:COG1131   77 YVPQEP--ALYPDLTVRENLRFFARLY-GLPRKEARERIDELLELFGLTDAA---DRKVGTLSGGMKQRLGLALALLHDP 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 188 AVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:COG1131  151 ELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
330-557 3.67e-41

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 152.92  E-value: 3.67e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 330 LNRVTR---EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAasklqPLRRDIQFI 406
Cdd:COG3839    6 LENVSKsygGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLP-----PKDRNIAMV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 407 FQDpYAsLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLPeHAWRYPHEFSGGQRQRICIARALALNPKVII 486
Cdd:COG3839   81 FQS-YA-LYPHMTVYENIAFPLKLRKVPKAEI-DRRVREAAELLGLED-LLDRKPKQLSGGQRQRVALGRALVREPKVFL 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 487 ADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHD----MAvverISHRVAVMYLGQIVEIGTRRAVFENPQH 557
Cdd:COG3839  157 LDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveaMT----LADRIAVMNDGRIQQVGTPEELYDRPAN 227
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
314-559 1.05e-40

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 148.26  E-value: 1.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRidtlaA 393
Cdd:cd03296    3 IEVRNVSKRFG-----------DFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGED-----A 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDpYAsLDPRQTVGYSILEPLRVHGLLQG---DAGSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQ 470
Cdd:cd03296   67 TDVPVQERNVGFVFQH-YA-LFRHMTVFDNVAFGLRVKPRSERppeAEIRAKVHELLKLVQL-DWLADRYPAQLSGGQRQ 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRA 550
Cdd:cd03296  144 RVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDE 223

                 ....*....
gi 949724212 551 VFENPQHPY 559
Cdd:cd03296  224 VYDHPASPF 232
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
315-541 1.17e-40

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 147.23  E-value: 1.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 315 RVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaAS 394
Cdd:cd03225    1 ELKNLSFSYP---------DGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLT---KL 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 395 KLQPLRRDIQFIFQDPyaslDpRQTVGYSILE----PLRVHGLLQGDAgSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQ 470
Cdd:cd03225   69 SLKELRRKVGLVFQNP----D-DQFFGPTVEEevafGLENLGLPEEEI-EERVEEALELVGLE-GLRDRSPFTLSGGQKQ 141
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQ 541
Cdd:cd03225  142 RVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
15-266 1.59e-40

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 147.65  E-value: 1.59e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQeqQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQS 94
Cdd:cd03261    3 LRGLTKSFGG--RTV--LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDG----------EDISGLS 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  95 ASQMRHVRgADIAMIFQEP--MTSLnpvfTVGEQIAESIRLHQGASHEE--AMVEAKrmLDQVRIPEAKailSRYPHQLS 170
Cdd:cd03261   69 EAELYRLR-RRMGMLFQSGalFDSL----TVFENVAFPLREHTRLSEEEirEIVLEK--LEAVGLRGAE---DLYPAELS 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 171 GGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVET 250
Cdd:cd03261  139 GGMKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAE 218
                        250
                 ....*....|....*.
gi 949724212 251 GSVEQIFHApQHPYTK 266
Cdd:cd03261  219 GTPEELRAS-DDPLVR 233
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
29-542 3.50e-40

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 153.44  E-value: 3.50e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   29 VSAVRNLSFRLKRGETLAIVGESGSGKS--VTALSLMHLIEQAGGEVSCDEMLLRrrnrqvielgeqsASQMRHVRGADI 106
Cdd:TIGR02633  14 VKALDGIDLEVRPGECVGLCGENGAGKStlMKILSGVYPHGTWDGEIYWSGSPLK-------------ASNIRDTERAGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  107 AMIFQEPMtsLNPVFTVGEQI--AESIRLHQGASHEEAMV-EAKRMLDQVRIPEAKaiLSRYPHQLSGGMRQRVMIAMAL 183
Cdd:TIGR02633  81 VIIHQELT--LVPELSVAENIflGNEITLPGGRMAYNAMYlRAKNLLRELQLDADN--VTRPVGDYGGGQQQLVEIAKAL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIfhapqhp 263
Cdd:TIGR02633 157 NKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTM------- 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  264 ytkallaAVPQLGA-MNGHELPRRFPlislHDPSHVepqteqdtvveGEPILRVRNLVTRFPlrsgilnrVTREVHAVEN 342
Cdd:TIGR02633 229 -------SEDDIITmMVGREITSLYP----HEPHEI-----------GDVILEARNLTCWDV--------INPHRKRVDD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  343 VSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ-RGEIIFNGQRIDTlaASKLQPLRRDIQFIFQD-PYASLDPRQTV 420
Cdd:TIGR02633 279 VSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDI--RNPAQAIRAGIAMVPEDrKRHGIVPILGV 356
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  421 GYSI----LEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:TIGR02633 357 GKNItlsvLKSFCFKMRIDAAAELQIIGSAIQRLKVKTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDV 436
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 949724212  497 SIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:TIGR02633 437 GAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
314-546 3.79e-40

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 145.86  E-value: 3.79e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaa 393
Cdd:cd03301    1 VELENVTKRFG-----------NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV----- 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDpYAsLDPRQTVGYSILEPLRVHGLLQG--DAGSKRVAWLLERVGLLPehawRYPHEFSGGQRQR 471
Cdd:cd03301   65 TDLPPKDRDIAMVFQN-YA-LYPHMTVYDNIAFGLKLRKVPKDeiDERVREVAELLQIEHLLD----RKPKQLSGGQRQR 138
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03301  139 VALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
9-242 5.60e-40

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 146.77  E-value: 5.60e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDemllrrrNRQV 87
Cdd:COG1116    4 AAPALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKS-TLLRLIAgLEKPTSGEVLVD-------GKPV 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  88 IELGeqsasqmrhvrgADIAMIFQEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAkaiLSRYPH 167
Cdd:COG1116   76 TGPG------------PDRGVVFQEP--ALLPWLTVLDNVALGLEL-RGVPKAERRERARELLELVGLAGF---EDAYPH 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDV----TIQAQILQlikvLQQDMSMGVIFITHDmgvVAD---IADRVL 240
Cdd:COG1116  138 QLSGGMRQRVAIARALANDPEVLLMDEPFGALDAltreRLQDELLR----LWQETGKTVLFVTHD---VDEavfLADRVV 210

                 ..
gi 949724212 241 VM 242
Cdd:COG1116  211 VL 212
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
314-542 9.06e-40

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 144.57  E-value: 9.06e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPLRSgILNrvtrevhaveNVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:COG4619    1 LELEGLSFRVGGKP-ILS----------PVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPP 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLqplRRDIQFIFQDPYAsldPRQTVGYSILEPLRVHGLlqgDAGSKRVAWLLERVGLlPEHAWRYP-HEFSGGQRQRI 472
Cdd:COG4619   70 PEW---RRQVAYVPQEPAL---WGGTVRDNLPFPFQLRER---KFDRERALELLERLGL-PPDILDKPvERLSGGERQRL 139
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 473 CIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:COG4619  140 ALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
311-567 1.25e-39

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 145.74  E-value: 1.25e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  311 EPILRVRNLVTRFPLRSGilnrvtrevhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIF---NGQR 387
Cdd:TIGR02323   1 KPLLQVSGLSKSYGGGKG-----------CRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYimrSGAE 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  388 IDTLA---ASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHGLLQ-GDAGSKRVAWLlERVGLLPEHAWRYPHE 463
Cdd:TIGR02323  70 LELYQlseAERRRLMRTEWGFVHQNPRDGLRMRVSAGANIGERLMAIGARHyGNIRATAQDWL-EEVEIDPTRIDDLPRA 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  464 FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:TIGR02323 149 FSGGMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVV 228
                         250       260
                  ....*....|....*....|....
gi 949724212  544 EIGTRRAVFENPQHPYTRKLMAAV 567
Cdd:TIGR02323 229 ESGLTDQVLDDPQHPYTQLLVSSI 252
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
31-251 3.73e-39

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 143.04  E-value: 3.73e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRgaDIAMIF 110
Cdd:cd03259   15 ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILID--------------GRDVTGVPPERR--NIGMVF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:cd03259   79 QDY--ALFPHLTVAENIAFGLKL-RGVPKAEIRARVRELLELVGLEG---LLNRYPHELSGGQQQRVALARALAREPSLL 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03259  153 LLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
340-489 6.38e-39

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 140.09  E-value: 6.38e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaASKLQPLRRDIQFIFQDPyaSLDPRQT 419
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLT---DDERKSLRKEIGYVFQDP--QLFPRLT 75
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212  420 VGYSILEPLRVHGLLQGDAGSkRVAWLLERVGL---LPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADE 489
Cdd:pfam00005  76 VRENLRLGLLLKGLSKREKDA-RAEEALEKLGLgdlADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDE 147
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
314-547 6.94e-39

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 143.46  E-value: 6.94e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGqrIDtlAA 393
Cdd:COG4555    2 IEVENLSKKY-----------GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDG--ED--VR 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDPYasLDPRQTVgysiLEPLRVHGLLQGDAGS---KRVAWLLERVGLlPEHAWRYPHEFSGGQRQ 470
Cdd:COG4555   67 KEPREARRQIGVLPDERG--LYDRLTV----RENIRYFAELYGLFDEelkKRIEELIELLGL-EEFLDRRVGELSTGMKK 139
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:COG4555  140 KVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGS 215
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
340-566 1.70e-38

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 142.53  E-value: 1.70e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRL----VESQRGEIIFNGQRIdtlAASKLQPlrRDIQFIFQDPYASLD 415
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGIlpagVRQTAGRVLLDGKPV---APCALRG--RKIATIMQNPRSAFN 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILEPLRVHGLLQGDAgskRVAWLLERVGLlpEHAWR----YPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:PRK10418  94 PLHTMHTHARETCLALGKPADDA---TLTAALEAVGL--ENAARvlklYPFEMSGGMLQRMMIALALLCEAPFIIADEPT 168
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 492 SALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAA 566
Cdd:PRK10418 169 TDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA 243
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
29-273 2.66e-38

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 142.40  E-value: 2.66e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDemllrrrNRQVIELgeqSASQMRHVRGADIA 107
Cdd:cd03294   37 TVGVNDVSLDVREGEIFVIMGLSGSGKS-TLLRCINrLIEPTSGKVLID-------GQDIAAM---SRKELRELRRKKIS 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:cd03294  106 MVFQS--FALLPHRTVLENVAFGLEV-QGVPRAEREERAAEALELVGL---EGWEHKYPDELSGGMQQRVGLARALAVDP 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 188 AVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKA 267
Cdd:cd03294  180 DILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVRE 259

                 ....*.
gi 949724212 268 LLAAVP 273
Cdd:cd03294  260 FFRGVD 265
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
29-542 1.31e-37

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 146.23  E-value: 1.31e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQA------GGEVscdemllrrrnrqVIELGEQSASQMRHVR 102
Cdd:PRK13549  18 VKALDNVSLKVRAGEIVSLCGENGAGKS----TLMKVLSGVyphgtyEGEI-------------IFEGEELQASNIRDTE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 103 GADIAMIFQEPMtsLNPVFTVGEQI--AESIrLHQGASHEEAMV-EAKRMLDQVRI---PEAKAilsrypHQLSGGMRQR 176
Cdd:PRK13549  81 RAGIAIIHQELA--LVKELSVLENIflGNEI-TPGGIMDYDAMYlRAQKLLAQLKLdinPATPV------GNLGLGQQQL 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQqdmSMGV--IFITHDMGVVADIADRVLVMYQGEAVETGSVE 254
Cdd:PRK13549 152 VEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLK---AHGIacIYISHKLNEVKAISDTICVIRDGRHIGTRPAA 228
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 255 QIfhapqhpytkallaAVPQLGA-MNGHELPRRFPlislHDPSHVepqteqdtvveGEPILRVRNLVTRFPlrsgilnrV 333
Cdd:PRK13549 229 GM--------------TEDDIITmMVGRELTALYP----REPHTI-----------GEVILEVRNLTAWDP--------V 271
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 334 TREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ-RGEIIFNGQRIDTlaASKLQPLRRDIQFIFQDPYA 412
Cdd:PRK13549 272 NPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRwEGEIFIDGKPVKI--RNPQQAIAQGIAMVPEDRKR 349
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 -SLDPRQTVGYSI----LEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIA 487
Cdd:PRK13549 350 dGIVPVMGVGKNItlaaLDRFTGGSRIDDAAELKTILESIQRLKVKTASPELAIARLSGGNQQKAVLAKCLLLNPKILIL 429
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 488 DESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:PRK13549 430 DEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKL 483
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
8-276 2.47e-37

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 140.15  E-value: 2.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   8 DASDVLAVSNLNiaFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrnrqv 87
Cdd:PRK13635   1 MKEEIIRVEHIS--FRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGM--------- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  88 iELGEQSASQMRhvrgADIAMIFQEPmtslNPVF---TVGEQIAESIRlHQGASHEEaMVE-AKRMLDQVRIPEakaILS 163
Cdd:PRK13635  70 -VLSEETVWDVR----RQVGMVFQNP----DNQFvgaTVQDDVAFGLE-NIGVPREE-MVErVDQALRQVGMED---FLN 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 164 RYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADiADRVLVMY 243
Cdd:PRK13635 136 REPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMN 214
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 949724212 244 QGEAVETGSVEQIFHAPQH--------PYTKALLAAVPQLG 276
Cdd:PRK13635 215 KGEILEEGTPEEIFKSGHMlqeigldvPFSVKLKELLKRNG 255
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
13-256 6.39e-37

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 137.31  E-value: 6.39e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ------AGGEVSCDEMLLRRRNRQ 86
Cdd:cd03260    1 IELRDLNVYYGDKH----ALKDISLDIPKGEITALIGPSGCGKS-TLLRLLNRLNDlipgapDEGEVLLDGKDIYDLDVD 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  87 VIELGEQsasqmrhvrgadIAMIFQEPmtslNPV-FTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIP-EAKAILSr 164
Cdd:cd03260   76 VLELRRR------------VGMVFQKP----NPFpGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWdEVKDRLH- 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 165 yPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIADRVLVMYQ 244
Cdd:cd03260  139 -ALGLSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYT--IVIVTHNMQQAARVADRTAFLLN 215
                        250
                 ....*....|..
gi 949724212 245 GEAVETGSVEQI 256
Cdd:cd03260  216 GRLVEFGPTEQI 227
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
308-555 8.28e-37

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 141.24  E-value: 8.28e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 308 VEGEPILRVRNLVTRFPlrsgilnrvTREVhaVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIF 383
Cdd:PRK09452   9 SSLSPLVELRGISKSFD---------GKEV--ISNLDLTINNGEFLTLLGPSGCGKTT----VLRLIagfeTPDSGRIML 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 384 NGQRIDTLAASKlqplrRDIQFIFQDpYAsLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHE 463
Cdd:PRK09452  74 DGQDITHVPAEN-----RHVNTVFQS-YA-LFPHMTVFENVAFGLRMQKTPAAEI-TPRVMEALRMVQL-EEFAQRKPHQ 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 464 FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:PRK09452 145 LSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIE 224
                        250
                 ....*....|..
gi 949724212 544 EIGTRRAVFENP 555
Cdd:PRK09452 225 QDGTPREIYEEP 236
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
312-571 9.20e-37

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 141.13  E-value: 9.20e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFplrSGIlnrvtrevHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtl 391
Cdd:PRK11607  18 PLLEIRNLTKSF---DGQ--------HAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL--- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 aaSKLQPLRRDIQFIFQDpYAsLDPRQTVGYSILEPLRVHGLLQGDAGSkRVAWLLERVGLLpEHAWRYPHEFSGGQRQR 471
Cdd:PRK11607  84 --SHVPPYQRPINMMFQS-YA-LFPHMTVEQNIAFGLKQDKLPKAEIAS-RVNEMLGLVHMQ-EFAKRKPHQLSGGQRQR 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:PRK11607 158 VALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
                        250       260
                 ....*....|....*....|
gi 949724212 552 FENPQHPYTRKLMAAVPVAD 571
Cdd:PRK11607 238 YEHPTTRYSAEFIGSVNVFE 257
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
339-556 1.80e-36

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 136.68  E-value: 1.80e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRID---TLAASKLQPLRRDIQFIFQDpYaSLD 415
Cdd:PRK11124  17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDfskTPSDKAIRELRRNVGMVFQQ-Y-NLW 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILE-PLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK11124  95 PHLTVQQNLIEaPCRVLGLSKDQA-LARAEKLLERLRL-KPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAAL 172
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 495 DVSIRGQIINLMLDLQrELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAvFENPQ 556
Cdd:PRK11124 173 DPEITAQIVSIIRELA-ETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC-FTQPQ 232
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
31-271 3.18e-36

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 135.89  E-value: 3.18e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQSASQMRHvrgaDIAMIF 110
Cdd:cd03295   16 AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDG----------EDIREQDPVELRR----KIGYVI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKaILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:cd03295   82 QQ--IGLFPHMTVEENIALVPKL-LKWPKEKIRERADELLALVGLDPAE-FADRYPHELSGGQQQRVGVARALAADPPLL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLA 270
Cdd:cd03295  158 LMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFVG 237

                 .
gi 949724212 271 A 271
Cdd:cd03295  238 A 238
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
12-272 4.82e-36

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 135.56  E-value: 4.82e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFeqeqQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEVSCDEMLLRRRNRQviEL 90
Cdd:COG1120    1 MLEAENLSVGY----GGRPVLDDVSLSLPPGEVTALLGPNGSGKS-TLLrALAGLLKPSSGEVLLDGRDLASLSRR--EL 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 GEQsasqmrhvrgadIAMIFQEPMTSLNpvFTVgeqiAESIRL----HQGA-----SHEEAMVEakRMLDQVRIpEAKAi 161
Cdd:COG1120   74 ARR------------IAYVPQEPPAPFG--LTV----RELVALgrypHLGLfgrpsAEDREAVE--EALERTGL-EHLA- 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 162 lSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLV 241
Cdd:COG1120  132 -DRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVL 210
                        250       260       270
                 ....*....|....*....|....*....|.
gi 949724212 242 MYQGEAVETGSVEQIFhapqhpyTKALLAAV 272
Cdd:COG1120  211 LKDGRIVAQGPPEEVL-------TPELLEEV 234
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
15-246 6.13e-36

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 134.19  E-value: 6.13e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrQVIELGEQS 94
Cdd:cd03262    3 IKNLHKSFGDFH----VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDG--------LKLTDDKKN 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  95 ASQMRhvrgADIAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEaKAilSRYPHQLSGGMR 174
Cdd:cd03262   71 INELR----QKVGMVFQQ--FNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLAD-KA--DAYPAQLSGGQQ 141
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 175 QRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQD-MSMgvIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03262  142 QRVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEgMTM--VVVTHEMGFAREVADRVIFMDDGR 212
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
19-257 9.13e-36

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 135.25  E-value: 9.13e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRrrnrqvielgeqSASQM 98
Cdd:TIGR04520   5 NVSFSYPESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTL------------DEENL 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   99 RHVRGAdIAMIFQepmtslNP--VF---TVGEQIA---ESirlhQGASHEEaMVEakrmldqvRIPEA------KAILSR 164
Cdd:TIGR04520  73 WEIRKK-VGMVFQ------NPdnQFvgaTVEDDVAfglEN----LGVPREE-MRK--------RVDEAlklvgmEDFRDR 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  165 YPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADiADRVLVMYQ 244
Cdd:TIGR04520 133 EPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNK 211
                         250
                  ....*....|...
gi 949724212  245 GEAVETGSVEQIF 257
Cdd:TIGR04520 212 GKIVAEGTPREIF 224
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
355-569 9.76e-36

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 136.85  E-value: 9.76e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  355 LVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaaSKLQPLRRDIQFIFQDpYAsLDPRQTVGYSILEPLRVHGLL 434
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV-----TNVPPHLRHINMVFQS-YA-LFPHMTVEENVAFGLKMRKVP 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  435 QGDAGSkRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELG 514
Cdd:TIGR01187  74 RAEIKP-RVLEALRLVQL-EEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLG 151
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212  515 IAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVPV 569
Cdd:TIGR01187 152 ITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINV 206
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
29-551 1.12e-35

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 140.96  E-value: 1.12e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGGEVSCDEMLLRRRNRQVIELGEQSASQMrhvrgaDIAM 108
Cdd:PRK15439  24 VEVLKGIDFTLHAGEVHALLGGNGAGKS----TLMKII---AGIVPPDSGTLEIGGNPCARLTPAKAHQL------GIYL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPMtsLNPVFTVGEQIAesIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILsryphqLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK15439  91 VPQEPL--LFPNLSVKENIL--FGLPKRQASMQKMKQLLAALGCQLDLDSSAGS------LEVADRQIVEILRGLMRDSR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHApqhpytkAL 268
Cdd:PRK15439 161 ILILDEPTASLTPAETERLFSRIRELLA-QGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTD-------DI 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 269 LAAV-PQLGAMNGHELPRrfplISLHDPSHvEPQTEQDTvvegePILRVRNLvtrfplrSGilnrvtrevHAVENVSFDL 347
Cdd:PRK15439 233 IQAItPAAREKSLSASQK----LWLELPGN-RRQQAAGA-----PVLTVEDL-------TG---------EGFRNISLEV 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 348 WPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaaSKLQPLRRDIQFIFQDpyasldpRQTVGYSILEP 427
Cdd:PRK15439 287 RAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINAL--STAQRLARGLVYLPED-------RQSSGLYLDAP 357
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 428 LR--VHGLLQGDAG----SKRVAWLLER----VGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PRK15439 358 LAwnVCALTHNRRGfwikPARENAVLERyrraLNIKFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVS 437
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....
gi 949724212 498 IRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:PRK15439 438 ARNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAAI 490
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
29-264 1.30e-35

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 137.15  E-value: 1.30e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI----EQAGGEvscdemllrrrnrqvIELGEQSASQMR-HVRg 103
Cdd:COG3842   18 VTALDDVSLSIEPGEFVALLGPSGCGKT----TLLRMIagfeTPDSGR---------------ILLDGRDVTGLPpEKR- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 104 aDIAMIFQEPmtSLNPVFTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPE-AKailsRYPHQLSGGMRQRVMIAMA 182
Cdd:COG3842   78 -NVGMVFQDY--ALFPHLTVAENVAFGLR-MRGVPKAEIRARVAELLELVGLEGlAD----RYPHQLSGGQQQRVALARA 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 183 LSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQH 262
Cdd:COG3842  150 LAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPAT 229

                 ..
gi 949724212 263 PY 264
Cdd:COG3842  230 RF 231
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
312-588 1.52e-35

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 136.47  E-value: 1.52e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRlVESQRGEIIFNGQRIDTL 391
Cdd:PRK15093   2 PLLDIRNLTIEFKTSDG-------WVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICG-VTKDNWRVTADRMRFDDI 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AASKLQPLRR------DIQFIFQDPYASLDPRQTVGYSILEPlrVHGLLQGDAGSKRVAW-------LLERVGLL-PEHA 457
Cdd:PRK15093  74 DLLRLSPRERrklvghNVSMIFQEPQSCLDPSERVGRQLMQN--IPGWTYKGRWWQRFGWrkrraieLLHRVGIKdHKDA 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 458 WR-YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAV 536
Cdd:PRK15093 152 MRsFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINV 231
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 949724212 537 MYLGQIVEIGTRRAVFENPQHPYTRKLMAAVP-VADPSHHRPQRVLLSDDIPS 588
Cdd:PRK15093 232 LYCGQTVETAPSKELVTTPHHPYTQALIRAIPdFGSAMPHKSRLNTLPGAIPL 284
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
32-197 1.59e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 130.85  E-value: 1.59e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRGADIAMIFQ 111
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLD--------------GQDLTDDERKSLRKEIGYVFQ 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  112 EPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPE-AKAILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:pfam00005  67 DP--QLFPRLTVRENLRLGLLL-KGLSKREKDARAEEALEKLGLGDlADRPVGERPGTLSGGQRQRVAIARALLTKPKLL 143

                  ....*..
gi 949724212  191 IADEPTT 197
Cdd:pfam00005 144 LLDEPTA 150
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
311-566 2.02e-35

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 134.76  E-value: 2.02e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridT 390
Cdd:PRK13635   3 EEIIRVEHISFRYP---------DAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGM---V 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LAASKLQPLRRDIQFIFQDPyasldPRQTVGYSILEP----LRVHGLLQgDAGSKRVAWLLERVGLLpEHAWRYPHEFSG 466
Cdd:PRK13635  71 LSEETVWDVRRQVGMVFQNP-----DNQFVGATVQDDvafgLENIGVPR-EEMVERVDQALRQVGME-DFLNREPHRLSG 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 467 GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIG 546
Cdd:PRK13635 144 GQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEG 222
                        250       260
                 ....*....|....*....|....*...
gi 949724212 547 TRRAVFENPQH--------PYTRKLMAA 566
Cdd:PRK13635 223 TPEEIFKSGHMlqeigldvPFSVKLKEL 250
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
314-556 2.73e-35

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 132.95  E-value: 2.73e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03219    1 LEVRGLTKRF-----------GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPP 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLqpLRRDIQFIFQDPyaSLDPRQTVgysiLEPLRVHGLLQGDAGS-------------KRVAWLLERVGLlPEHAWRY 460
Cdd:cd03219   70 HEI--ARLGIGRTFQIP--RLFPELTV----LENVMVAAQARTGSGLllararreerearERAEELLERVGL-ADLADRP 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 461 PHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLG 540
Cdd:cd03219  141 AGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEHDMDVVMSLADRVTVLDQG 219
                        250
                 ....*....|....*.
gi 949724212 541 QIVEIGTRRAVFENPQ 556
Cdd:cd03219  220 RVIAEGTPDEVRNNPR 235
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
15-261 3.20e-35

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 133.22  E-value: 3.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCdemllrrRNRQVIELGEQ 93
Cdd:PRK11124   5 LNGINCFYGAHQ----ALFDITLDCPQGETLVLLGPSGAGKS-SLLRVLNLLEMPrSGTLNI-------AGNHFDFSKTP 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 SASQMRHVRgADIAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIpEAKAilSRYPHQLSGGM 173
Cdd:PRK11124  73 SDKAIRELR-RNVGMVFQQ--YNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRL-KPYA--DRFPLHLSGGQ 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 174 RQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIfITHDMGVVADIADRVLVMYQGEAVETGSV 253
Cdd:PRK11124 147 QQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVI-VTHEVEVARKTASRVVYMENGHIVEQGDA 225

                 ....*...
gi 949724212 254 EQiFHAPQ 261
Cdd:PRK11124 226 SC-FTQPQ 232
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
339-556 3.82e-35

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 132.83  E-value: 3.82e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRID---TLAASKLQPLRRDIQFIFQDpYaSLD 415
Cdd:COG4161   17 ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDfsqKPSEKAIRLLRQKVGMVFQQ-Y-NLW 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILE-PLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:COG4161   95 PHLTVMENLIEaPCKVLGLSKEQA-REKAMKLLARLRL-TDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAAL 172
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 495 DVSIRGQIINLMLDLQrELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTrRAVFENPQ 556
Cdd:COG4161  173 DPEITAQVVEIIRELS-QTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD-ASHFTQPQ 232
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
314-547 4.06e-35

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 132.24  E-value: 4.06e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03263    1 LQIRNLTKTYK---------KGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRK 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SklqpLRRDIQFIFQDpyASLDPRQTVgysiLEPLRVHGLLQG---DAGSKRVAWLLERVGLLPeHAWRYPHEFSGGQRQ 470
Cdd:cd03263   72 A----ARQSLGYCPQF--DALFDELTV----REHLRFYARLKGlpkSEIKEEVELLLRVLGLTD-KANKRARTLSGGMKR 140
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:cd03263  141 KLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRKGRSI--ILTTHSMDEAEALCDRIAIMSDGKLRCIGS 215
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
342-546 4.72e-35

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 131.65  E-value: 4.72e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLwPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRI-DTLAASKLQPLRRDIQFIFQDpyASLDPRQTV 420
Cdd:cd03297   16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfDSRKKINLPPQQRKIGLVFQQ--YALFPHLNV 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 421 GYSILEPLRVHGLLQGdagSKRVAWLLERVGLlpEH-AWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR 499
Cdd:cd03297   93 RENLAFGLKRKRNRED---RISVDELLDLLGL--DHlLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALR 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 949724212 500 GQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03297  168 LQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
330-541 7.44e-35

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 129.29  E-value: 7.44e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 330 LNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQPLRRDIQFIFQd 409
Cdd:cd00267    5 LSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDI---AKLPLEELRRRIGYVPQ- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 410 pyasldprqtvgysileplrvhgllqgdagskrvawllervgllpehawrypheFSGGQRQRICIARALALNPKVIIADE 489
Cdd:cd00267   81 ------------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDE 106
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 949724212 490 SVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQ 541
Cdd:cd00267  107 PTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
336-562 9.59e-35

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 131.96  E-value: 9.59e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE-----SQRGEIIFNGQRIDTLAASKLqplRRDIQFIFQDP 410
Cdd:PRK14247  15 QVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElypeaRVSGEVYLDGQDIFKMDVIEL---RRRVQMVFQIP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 411 yaslDPRQTVgySILEPLRVHGLLQGDAGSK-----RVAWLLERVGLLPEHAWRY---PHEFSGGQRQRICIARALALNP 482
Cdd:PRK14247  92 ----NPIPNL--SIFENVALGLKLNRLVKSKkelqeRVRWALEKAQLWDEVKDRLdapAGKLSGGQQQRLCIARALAFQP 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 483 KVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRK 562
Cdd:PRK14247 166 EVLLADEPTANLDPENTAKIESLFLELKKDMTI--VLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELTEK 243
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
340-556 1.24e-34

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 131.30  E-value: 1.24e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasklQPLRRDIQFIFQDpYAsLDPRQT 419
Cdd:cd03299   15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNL-----PPEKRDISYVPQN-YA-LFPHMT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYSILEPLRvHGLLQGDAGSKRVAWLLERVGLlpEHAW-RYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSI 498
Cdd:cd03299   88 VYKNIAYGLK-KRKVDKKEIERKVLEIAEMLGI--DHLLnRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRT 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 499 RGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:cd03299  165 KEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPK 222
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
13-246 2.19e-34

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 128.46  E-value: 2.19e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIELGE 92
Cdd:cd03229    1 LELKNVSKRYGQKT----VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 qsasqmrhvrgaDIAMIFQEPmtSLNPVFTVGEQIAESirlhqgasheeamveakrmldqvripeakailsryphqLSGG 172
Cdd:cd03229   77 ------------RIGMVFQDF--ALFPHLTVLENIALG--------------------------------------LSGG 104
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03229  105 QQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
338-562 2.28e-34

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 131.12  E-value: 2.28e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ-----RGEIIFNGQRIDTLAASKLQpLRRDIQFIFQdpYA 412
Cdd:PRK14267  18 HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIYSPDVDPIE-VRREVGMVFQ--YP 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 SLDPRQTVGYSILEPLRVHGLLQG-DAGSKRVAWLLERVGLLPEHAWR---YPHEFSGGQRQRICIARALALNPKVIIAD 488
Cdd:PRK14267  95 NPFPHLTIYDNVAIGVKLNGLVKSkKELDERVEWALKKAALWDEVKDRlndYPSNLSGGQRQRLVIARALAMKPKILLMD 174
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 489 ESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRK 562
Cdd:PRK14267 175 EPTANIDPVGTAKIEELLFELKKEYTI--VLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEK 246
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
314-542 5.03e-34

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 127.51  E-value: 5.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03230    1 IEVRNLSKRY-----------GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPE 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SklqpLRRDIQFIFQDP--YASLDPRQTVgysileplrvhgllqgdagskrvawllervgllpehawryphEFSGGQRQR 471
Cdd:cd03230   70 E----VKRRIGYLPEEPslYENLTVRENL------------------------------------------KLSGGMKQR 103
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:cd03230  104 LALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
313-567 1.23e-33

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 129.01  E-value: 1.23e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPlrsgilnrvTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLA 392
Cdd:COG1120    1 MLEAENLSVGYG---------GRPV--LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLS 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLqplRRDIQFIFQDPYASldprqtvgysilEPLRV-----------HGLLQ--GDAGSKRVAWLLERVGLLpEHAWR 459
Cdd:COG1120   70 RREL---ARRIAYVPQEPPAP------------FGLTVrelvalgryphLGLFGrpSAEDREAVEEALERTGLE-HLADR 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 460 YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYL 539
Cdd:COG1120  134 PVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKD 213
                        250       260
                 ....*....|....*....|....*...
gi 949724212 540 GQIVEIGTRRAVFenpqhpyTRKLMAAV 567
Cdd:COG1120  214 GRIVAQGPPEEVL-------TPELLEEV 234
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
35-269 1.70e-33

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 128.71  E-value: 1.70e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  35 LSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDEMLLRrrnrQVIELGEQSaSQMRHVRgADIAMIFQEp 113
Cdd:PRK11264  22 IDLEVKPGEVVAIIGPSGSGKT-TLLRCINLLEQpEAGTIRVGDITID----TARSLSQQK-GLIRQLR-QHVGFVFQN- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 114 mTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVLIAD 193
Cdd:PRK11264  94 -FNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKE---TSYPRRLSGGQQQRVAIARALAMRPEVILFD 169
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 194 EPTTALDVTIQAQILQLIKVLQQDMSMGVIfITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALL 269
Cdd:PRK11264 170 EPTSALDPELVGEVLNTIRQLAQEKRTMVI-VTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRTRQFL 244
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
12-256 1.89e-33

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 128.05  E-value: 1.89e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemLLRRRNRQVIELG 91
Cdd:COG4555    1 MIEVENLSKKYGKVP----ALKDVSFTAKDGEITGLLGPNGAGKT----TLLRML--AG--------LLKPDSGSILIDG 62
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRgADIAMIFQEPMtsLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSG 171
Cdd:COG4555   63 EDVRKEPREAR-RQIGVLPDERG--LYDRLTVRENIRYFAELY-GLFDEELKKRIEELIELLGLEE---FLDRRVGELST 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:COG4555  136 GMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKT-VLFSSHIMQEVEALCDRVVILHKGKVVAQG 214

                 ....*
gi 949724212 252 SVEQI 256
Cdd:COG4555  215 SLDEL 219
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
4-267 1.90e-33

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 128.62  E-value: 1.90e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   4 SDELDASDVLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SL--MH-LIEQA--GGEV---- 73
Cdd:COG1117    3 APASTLEPKIEVRNLNVYYGDKQ----ALKDINLDIPENKVTALIGPSGCGKS-TLLrCLnrMNdLIPGArvEGEIlldg 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  74 ------SCDEMLLRRRnrqvielgeqsasqmrhvrgadIAMIFQEPmtslNPvF--TVGEQIAESIRLHQGASHEE--AM 143
Cdd:COG1117   78 ediydpDVDVVELRRR----------------------VGMVFQKP----NP-FpkSIYDNVAYGLRLHGIKSKSEldEI 130
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 144 VEakRMLDQVRI-PEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgV 222
Cdd:COG1117  131 VE--ESLRKAALwDEVKDRLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYT--I 206
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 949724212 223 IFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKA 267
Cdd:COG1117  207 VIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTNPKDKRTED 251
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
314-541 2.04e-33

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 125.57  E-value: 2.04e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaa 393
Cdd:cd03228    1 IEFKNVSFSYP---------GRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDL-- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 sKLQPLRRDIQFIFQDPYasLDPRqTVGYSILeplrvhgllqgdagskrvawllervgllpehawryphefSGGQRQRIC 473
Cdd:cd03228   70 -DLESLRKNIAYVPQDPF--LFSG-TIRENIL---------------------------------------SGGQRQRIA 106
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 474 IARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERiSHRVAVMYLGQ 541
Cdd:cd03228  107 IARALLRDPPILILDEATSALDPETEALILEALRALAKGKTV--IVIAHRLSTIRD-ADRIIVLDDGR 171
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
12-250 2.69e-33

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 127.55  E-value: 2.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVscdeMLLRRrnrqviEL 90
Cdd:COG4181    8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKS-TLLGLLAGLDRPtSGTV----RLAGQ------DL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 GEQSASQMRHVRGADIAMIFQEPMtsLNPVFTVGEQIAESIRLhqgASHEEAMVEAKRMLDQV----RipeakaiLSRYP 166
Cdd:COG4181   77 FALDEDARARLRARHVGFVFQSFQ--LLPTLTALENVMLPLEL---AGRRDARARARALLERVglghR-------LDHYP 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGvVADIADRVLVMYQGE 246
Cdd:COG4181  145 AQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPA-LAARCDRVLRLRAGR 223

                 ....
gi 949724212 247 AVET 250
Cdd:COG4181  224 LVED 227
cbiO PRK13650
energy-coupling factor transporter ATPase;
10-287 4.42e-33

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 128.31  E-value: 4.42e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFEQEQQRVSaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRrrnrqvie 89
Cdd:PRK13650   2 SNIIEVKNLTFKYKEDQEKYT-LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLT-------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 lgEQSASQMRHvrgaDIAMIFQEPMTSLNPVfTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQL 169
Cdd:PRK13650  73 --EENVWDIRH----KIGMVFQNPDNQFVGA-TVEDDVAFGLE-NKGIPHEEMKERVNEALELVGMQDFK---EREPARL 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVAdIADRVLVMYQGEAVE 249
Cdd:PRK13650 142 SGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVES 220
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 949724212 250 TGSVEQIFHAPQH--------PYTKALLAAVPQlgamNGHELPRRF 287
Cdd:PRK13650 221 TSTPRELFSRGNDllqlgldiPFTTSLVQSLRQ----NGYDLPEGY 262
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
13-265 7.90e-33

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 129.50  E-value: 7.90e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGE 92
Cdd:COG1118    3 IEVRNISKRFGSFT----LLDDVSLEIASGELVALLGPSGSGKT----TLLRII--AG---------LETPDSGRIVLNG 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVRGADIAMIFQEPMtsLNPVFTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPE-AKailsRYPHQLSG 171
Cdd:COG1118   64 RDLFTNLPPRERRVGFVFQHYA--LFPHMTVAENIAFGLR-VRPPSKAEIRARVEELLELVQLEGlAD----RYPSQLSG 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:COG1118  137 GQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVG 216
                        250
                 ....*....|....
gi 949724212 252 SVEQIFHAPQHPYT 265
Cdd:COG1118  217 TPDEVYDRPATPFV 230
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
19-246 8.21e-33

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 125.31  E-value: 8.21e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemLLRRRNRQvielgEQSASQM 98
Cdd:COG4619    5 GLSFRVGGKPI--LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEI-----YLDGKPLS-----AMPPPEW 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHvrgaDIAMIFQEPmtslnPVF--TVGEQIAESIRLHQGASHEEamvEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQR 176
Cdd:COG4619   73 RR----QVAYVPQEP-----ALWggTVRDNLPFPFQLRERKFDRE---RALELLERLGLPPD--ILDKPVERLSGGERQR 138
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:COG4619  139 LALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGR 208
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
15-261 8.63e-33

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 126.28  E-value: 8.63e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQAggevscdemllrrRNRQVIELGEQ- 93
Cdd:COG4161    5 LKNINCFYGSHQ----ALFDINLECPSGETLVLLGPSGAGKS-SLLRVLNLLETP-------------DSGQLNIAGHQf 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 ------SASQMRHVRGaDIAMIFQEpmTSLNPVFTVGEQIAES-IRLhQGASHEEAMVEAKRMLDQVRIPEaKAilSRYP 166
Cdd:COG4161   67 dfsqkpSEKAIRLLRQ-KVGMVFQQ--YNLWPHLTVMENLIEApCKV-LGLSKEQAREKAMKLLARLRLTD-KA--DRFP 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdmsMGV--IFITHDMGVVADIADRVLVMYQ 244
Cdd:COG4161  140 LHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQ---TGItqVIVTHEVEFARKVASQVVYMEK 216
                        250
                 ....*....|....*..
gi 949724212 245 GEAVETGSVEqIFHAPQ 261
Cdd:COG4161  217 GRIIEQGDAS-HFTQPQ 232
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
31-261 1.47e-32

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 125.43  E-value: 1.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMhlieqAGGE-VSCDEMLLRrrNRQVIELGEqsasqmrHVRGadIAMI 109
Cdd:cd03300   15 ALDGVSLDIKEGEFFTLLGPSGCGKT-TLLRLI-----AGFEtPTSGEILLD--GKDITNLPP-------HKRP--VNTV 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSCRPAV 189
Cdd:cd03300   78 FQN--YALFPHLTVFENIAFGLRL-KKLPKAEIKERVAEALDLVQL---EGYANRKPSQLSGGQQQRVAIARALVNEPKV 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 190 LIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQ 261
Cdd:cd03300  152 LLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPA 223
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
311-560 2.03e-32

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 125.66  E-value: 2.03e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSgilnrvtrevhAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE-----SQRGEIIFNG 385
Cdd:PRK14239   3 EPILQVSDLSVYYNKKK-----------ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDlnpevTITGSIVYNG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 386 QRIDTLAASKLQpLRRDIQFIFQDPyaslDPrqtVGYSILEPLrVHGL-LQGDAGSKRVAWLLERvGLLPEHAWR----Y 460
Cdd:PRK14239  72 HNIYSPRTDTVD-LRKEIGMVFQQP----NP---FPMSIYENV-VYGLrLKGIKDKQVLDEAVEK-SLKGASIWDevkdR 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 461 PHE----FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAV 536
Cdd:PRK14239 142 LHDsalgLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTM--LLVTRSMQQASRISDRTGF 219
                        250       260
                 ....*....|....*....|....
gi 949724212 537 MYLGQIVEIGTRRAVFENPQHPYT 560
Cdd:PRK14239 220 FLDGDLIEYNDTKQMFMNPKHKET 243
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
342-567 8.60e-32

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 123.28  E-value: 8.60e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQpLRRDIQFIFQDPYasLDPRQTVg 421
Cdd:PRK09493  19 NIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERL-IRQEAGMVFQQFY--LFPHLTA- 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 422 ysiLE-----PLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:PRK09493  95 ---LEnvmfgPLRVRGASKEEA-EKQARELLAKVGL-AERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALDP 169
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 497 SIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAV 567
Cdd:PRK09493 170 ELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFLQHV 239
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
339-570 1.22e-31

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 127.07  E-value: 1.22e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRD-IQFIFQDpyASLDPR 417
Cdd:PRK10070  43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKkIAMVFQS--FALMPH 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILEPLRVHGLLQGDAGSKRVAwLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PRK10070 121 MTVLDNTAFGMELAGINAEERREKALD-ALRQVGL-ENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 498 IRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVPVA 570
Cdd:PRK10070 199 IRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDIS 271
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
340-543 1.35e-31

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 121.60  E-value: 1.35e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaasKLQPLRRDIQFIFQDPYasldpRQT 419
Cdd:cd03226   16 LDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI------KAKERRKSIGYVMQDVD-----YQL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYSILEPLRVhGLLQGDAGSKRVAWLLERVGLLPEHAwRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR 499
Cdd:cd03226   85 FTDSVREELLL-GLKELDAGNEQAETVLKDLDLYALKE-RHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNM 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 949724212 500 GQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:cd03226  163 ERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
316-564 1.45e-31

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 122.94  E-value: 1.45e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 316 VRNLVTRFPLRSgILNRVTREVHavenvsfdlwPGETLSLVGESGCGKSTTGRA--LLRLVESQR---GEIIFNGQRIDT 390
Cdd:PRK11264   6 VKNLVKKFHGQT-VLHGIDLEVK----------PGEVVAIIGPSGSGKTTLLRCinLLEQPEAGTirvGDITIDTARSLS 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LAASKLQPLRRDIQFIFQDpyASLDPRQTVGYSILE-PLRVHGLLQGDAgSKRVAWLLERVGLLPEHAwRYPHEFSGGQR 469
Cdd:PRK11264  75 QQKGLIRQLRQHVGFVFQN--FNLFPHRTVLENIIEgPVIVKGEPKEEA-TARARELLAKVGLAGKET-SYPRRLSGGQQ 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:PRK11264 151 QRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAK 229
                        250
                 ....*....|....*
gi 949724212 550 AVFENPQHPYTRKLM 564
Cdd:PRK11264 230 ALFADPQQPRTRQFL 244
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
12-245 1.56e-31

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 122.05  E-value: 1.56e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMhlieqaGGEVSCDEMLLRRRNRQVIELG 91
Cdd:TIGR02982   1 VISIRNLNHYYGHGSLRKQVLFDINLEINPGEIVILTGPSGSGKT-TLLTLI------GGLRSVQEGSLKVLGQELHGAS 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   92 EQSASQMRHvrgaDIAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAkaiLSRYPHQLSG 171
Cdd:TIGR02982  74 KKQLVQLRR----RIGYIFQA--HNLLGFLTARQNVQMALELQPNLSYQEARERARAMLEAVGLGDH---LNYYPHNLSG 144
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212  172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVaDIADRVLVMYQG 245
Cdd:TIGR02982 145 GQKQRVAIARALVHHPKLVLADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHDNRIL-DVADRILQMEDG 217
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
15-264 1.94e-31

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 122.45  E-value: 1.94e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGEQS 94
Cdd:cd03296    5 VRNVSKRFGDFV----ALDDVSLDIPSGELVALLGPSGSGKT----TLLRLI--AG---------LERPDSGTILFGGED 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  95 ASQMrHVRGADIAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMR 174
Cdd:cd03296   66 ATDV-PVQERNVGFVFQH--YALFRHMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQR 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 175 QRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVE 254
Cdd:cd03296  143 QRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPD 222
                        250
                 ....*....|
gi 949724212 255 QIFHAPQHPY 264
Cdd:cd03296  223 EVYDHPASPF 232
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
31-246 2.90e-31

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 119.81  E-value: 2.90e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRGaDIAMIF 110
Cdd:cd03230   15 ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVL--------------GKDIKKEPEEVKR-RIGYLP 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPmtSLNPVFTVGEQIaesirlhqgasheeamveakrmldqvripeakailsryphQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:cd03230   80 EEP--SLYENLTVRENL----------------------------------------KLSGGMKQRLALAQALLHDPELL 117
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03230  118 ILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGR 172
cbiO PRK13637
energy-coupling factor transporter ATPase;
336-554 3.82e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 122.85  E-value: 3.82e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdTLAASKLQPLRRDIQFIFQDPYASLD 415
Cdd:PRK13637  19 EKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDI-TDKKVKLSDIRKKVGLVFQYPEYQLF 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 pRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLPE-HAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK13637  98 -EETIEKDIAFGPINLGLSEEEI-ENRVKRAMNIVGLDYEdYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGL 175
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 495 DVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFEN 554
Cdd:PRK13637 176 DPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
311-559 4.83e-31

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 121.35  E-value: 4.83e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridt 390
Cdd:COG1121    4 MPAIELENLTVSY-----------GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK---- 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 laasKLQPLRRDIQFIFQdpYASLDP------RQTVGYSILEPLRVHGLLqGDAGSKRVAWLLERVGLLpEHAWRYPHEF 464
Cdd:COG1121   69 ----PPRRARRRIGYVPQ--RAEVDWdfpitvRDVVLMGRYGRRGLFRRP-SRADREAVDEALERVGLE-DLADRPIGEL 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 465 SGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMyLGQIVE 544
Cdd:COG1121  141 SGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRVLLL-NRGLVA 218
                        250
                 ....*....|....*..
gi 949724212 545 IGTRRAVF--ENPQHPY 559
Cdd:COG1121  219 HGPPEEVLtpENLSRAY 235
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
311-550 6.03e-31

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 120.62  E-value: 6.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQ 386
Cdd:COG4181    6 APIIELRGLTKTVGTGAG-------ELTILKGISLEVEAGESVAIVGASGSGKST----LLGLLagldRPTSGTVRLAGQ 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDTLAASKLQPLRRD-IQFIFQdpyaS--LDPRQTVgysiLE----PLrvhgLLQGDAGS-KRVAWLLERVGL--LPEH 456
Cdd:COG4181   75 DLFALDEDARARLRARhVGFVFQ----SfqLLPTLTA----LEnvmlPL----ELAGRRDArARARALLERVGLghRLDH 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 457 awrYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAV 536
Cdd:COG4181  143 ---YPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLR 218
                        250
                 ....*....|....
gi 949724212 537 MYLGQIVEIGTRRA 550
Cdd:COG4181  219 LRAGRLVEDTAATA 232
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
287-547 1.06e-30

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 126.80  E-value: 1.06e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 287 FPLISLHDPSHvePQTEQDTVVEGEPILRVRNLVTRFPLRSGILNrvtrevhaveNVSFDLWPGETLSLVGESGCGKSTT 366
Cdd:COG4988  312 FALLDAPEPAA--PAGTAPLPAAGPPSIELEDVSFSYPGGRPALD----------GLSLTIPPGERVALVGPSGAGKSTL 379
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 367 GRALLRLVESQRGEIIFNGQRIDTLAaskLQPLRRDIQFIFQDPYasldprqTVGYSILEPLRvhgLLQGDAGSKRVAWL 446
Cdd:COG4988  380 LNLLLGFLPPYSGSILINGVDLSDLD---PASWRRQIAWVPQNPY-------LFAGTIRENLR---LGRPDASDEELEAA 446
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 447 LERVGL------LP--------EHAWRypheFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRE 512
Cdd:COG4988  447 LEAAGLdefvaaLPdgldtplgEGGRG----LSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKG 522
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 949724212 513 LGIayLFISHDMAVVERISHRVaVMYLGQIVEIGT 547
Cdd:COG4988  523 RTV--ILITHRLALLAQADRIL-VLDDGRIVEQGT 554
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
12-245 1.42e-30

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 119.38  E-value: 1.42e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGG--EVSCDEMLLRRRNrqvie 89
Cdd:TIGR02211   1 LLKCENLGKRYQEGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKS----TLLHLL---GGldNPTSGEVLFNGQS----- 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   90 LGEQSASQMRHVRGADIAMIFQepMTSLNPVFTVGEQIAESIrLHQGASHEEAMVEAKRMLDQVripEAKAILSRYPHQL 169
Cdd:TIGR02211  69 LSKLSSNERAKLRNKKLGFIYQ--FHHLLPDFTALENVAMPL-LIGKKSVKEAKERAYEMLEKV---GLEHRINHRPSEL 142
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212  170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGvVADIADRVLVMYQG 245
Cdd:TIGR02211 143 SGGERQRVAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLE-LAKKLDRVLEMKDG 217
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
314-543 1.53e-30

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 117.14  E-value: 1.53e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTlaA 393
Cdd:cd03216    1 LELRGITKRFG-----------GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSF--A 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQdpyasldprqtvgysileplrvhgllqgdagskrvawllervgllpehawrypheFSGGQRQRIC 473
Cdd:cd03216   68 SPRDARRAGIAMVYQ-------------------------------------------------------LSVGERQMVE 92
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 474 IARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:cd03216   93 IARALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
19-257 1.76e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 120.48  E-value: 1.76e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNrqvielgeqsasqM 98
Cdd:PRK13632  12 NVSFSYPNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKEN-------------L 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHVRGaDIAMIFQEPmtslNPVF---TVGEQIAESIrlhqgashEEAMVEAKRMLD-------QVRIpeaKAILSRYPHQ 168
Cdd:PRK13632  79 KEIRK-KIGIIFQNP----DNQFigaTVEDDIAFGL--------ENKKVPPKKMKDiiddlakKVGM---EDYLDKEPQN 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVAdIADRVLVMYQGEAV 248
Cdd:PRK13632 143 LSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLI 221

                 ....*....
gi 949724212 249 ETGSVEQIF 257
Cdd:PRK13632 222 AQGKPKEIL 230
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
337-542 2.06e-30

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 118.66  E-value: 2.06e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 337 VHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDpyASLDP 416
Cdd:cd03292   14 TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRRKIGVVFQD--FRLLP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlpEHAWR-YPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:cd03292   92 DRNVYENVAFALEVTGVPPREI-RKRVPAALELVGL--SHKHRaLPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLD 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 949724212 496 VSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:cd03292  169 PDTTWEIMNLLKKINKA-GTTVVVATHAKELVDTTRHRVIALERGKL 214
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
32-261 2.25e-30

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 119.36  E-value: 2.25e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVtalslmhLIEQAGGEVSCDEMLLRRRNRQVIELgeqsASQMRhvrgaDIAMIFQ 111
Cdd:cd03299   15 LKNVSLEVERGDYFVILGPTGSGKSV-------LLETIAGFIKPDSGKILLNGKDITNL----PPEKR-----DISYVPQ 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EpmTSLNPVFTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:cd03299   79 N--YALFPHMTVYKNIAYGLK-KRKVDKKEIERKVLEIAEMLGIDH---LLNRKPETLSGGEQQRVAIARALVVNPKILL 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQ 261
Cdd:cd03299  153 LDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPK 222
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
311-537 2.82e-30

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 118.69  E-value: 2.82e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRsgilNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFN--GQRI 388
Cdd:COG4778    2 TTLLEVENLSKTFTLH----LQGGKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRhdGGWV 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 389 DTLAASKLQPL---RRDI----QFifqdpyasLD--PRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWR 459
Cdd:COG4778   78 DLAQASPREILalrRRTIgyvsQF--------LRviPRVSALDVVAEPLLERGVDREEA-RARARELLARLNL-PERLWD 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 460 -YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVM 537
Cdd:COG4778  148 lPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDV 225
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
298-559 3.11e-30

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 126.49  E-value: 3.11e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 298 VEPQTEQDTVVEGEPI--LRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE 375
Cdd:COG2274  456 PEREEGRSKLSLPRLKgdIELENVSFRYP---------GDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYE 526
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 376 SQRGEIIFNGQRIDTLAaskLQPLRRDIQFIFQDPYasLDPRqtvgySILEPLRVHgllQGDAGSKRVAWLLERVGLlpe 455
Cdd:COG2274  527 PTSGRILIDGIDLRQID---PASLRRQIGVVLQDVF--LFSG-----TIRENITLG---DPDATDEEIIEAARLAGL--- 590
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 456 hawrypHEF-------------------SGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIA 516
Cdd:COG2274  591 ------HDFiealpmgydtvvgeggsnlSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK--GRT 662
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 949724212 517 YLFISHDMAVVeRISHRVAVMYLGQIVEIGTRRAVFENPQHPY 559
Cdd:COG2274  663 VIIIAHRLSTI-RLADRIIVLDKGRIVEDGTHEELLARKGLYA 704
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
28-275 3.20e-30

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 118.75  E-value: 3.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   28 RVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGEQSASQMrHVRGADIA 107
Cdd:TIGR00968  12 SFQALDDVNLEVPTGSLVALLGPSGSGKS----TLLRII--AG---------LEQPDSGRIRLNGQDATRV-HARDRKIG 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  108 MIFQEpmTSLNPVFTVGEQIAESIRLHQgasHEEAMVEAK--RMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:TIGR00968  76 FVFQH--YALFKHLTVRDNIAFGLEIRK---HPKAKIKARveELLELVQL---EGLGDRYPNQLSGGQRQRVALARALAV 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  186 RPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYT 265
Cdd:TIGR00968 148 EPQVLLLDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFV 227
                         250
                  ....*....|
gi 949724212  266 KALLAAVPQL 275
Cdd:TIGR00968 228 MSFLGEVNVL 237
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
316-547 3.45e-30

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 118.24  E-value: 3.45e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 316 VRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASk 395
Cdd:cd03265    3 VENLVKKY-----------GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPRE- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 396 lqpLRRDIQFIFQDPyaSLDPRQTvGYsilEPLRVHGLLQGDAGSK---RVAWLLERVGLLpEHAWRYPHEFSGGQRQRI 472
Cdd:cd03265   71 ---VRRRIGIVFQDL--SVDDELT-GW---ENLYIHARLYGVPGAErreRIDELLDFVGLL-EAADRLVKTYSGGMRRRL 140
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 473 CIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:cd03265  141 EIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGT 215
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
29-251 3.90e-30

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 117.74  E-value: 3.90e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnRQVIELGEQSAsqmrhvrgaDIAM 108
Cdd:cd03301   13 VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGG-------RDVTDLPPKDR---------DIAM 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEpmTSLNPVFTVGEQIAESIRLHqGASHEEAmveAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:cd03301   77 VFQN--YALYPHMTVYDNIAFGLKLR-KVPKDEI---DERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPK 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03301  151 VFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
31-249 4.15e-30

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 118.23  E-value: 4.15e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDEMLLRR-RNRQVielgeqsaSQMRhvRgaDIAM 108
Cdd:COG2884   17 ALSDVSLEIEKGEFVFLTGPSGAGKS-TLLKLLYGEERPtSGQVLVNGQDLSRlKRREI--------PYLR--R--RIGV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEpmtslnpvF------TVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIpEAKAilSRYPHQLSGGMRQRVMIAMA 182
Cdd:COG2884   84 VFQD--------FrllpdrTVYENVALPLRVT-GKSRKEIRRRVREVLDLVGL-SDKA--KALPHELSGGEQQRVAIARA 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 183 LSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdmsMG--VIFITHDMGVVADIADRVLVMYQGEAVE 249
Cdd:COG2884  152 LVNRPELLLADEPTGNLDPETSWEIMELLEEINR---RGttVLIATHDLELVDRMPKRVLELEDGRLVR 217
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
340-546 4.22e-30

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 116.77  E-value: 4.22e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqplrrdiqfifqdpyasldpRQT 419
Cdd:cd03214   15 LDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKEL--------------------ARK 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYsileplrvhgLLQgdagskrvawLLERVGLLPEhAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR 499
Cdd:cd03214   75 IAY----------VPQ----------ALELLGLAHL-ADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQ 133
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 949724212 500 GQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03214  134 IELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
12-256 7.02e-30

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 118.24  E-value: 7.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQrvsAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEVSCDEmllrrrnrqvIEL 90
Cdd:COG3638    2 MLELRNLSKRYPGGTP---ALDDVSLEIERGEFVALIGPSGAGKS-TLLrCLNGLVEPTSGEILVDG----------QDV 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 GEQSASQMRHVRgADIAMIFQEP-----MTSLNPVFTvGeqiaesiRLHQ--------GASHEEAMVEAKRMLDQVRIPE 157
Cdd:COG3638   68 TALRGRALRRLR-RRIGMIFQQFnlvprLSVLTNVLA-G-------RLGRtstwrsllGLFPPEDRERALEALERVGLAD 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 158 aKAiLSRyPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIAD 237
Cdd:COG3638  139 -KA-YQR-ADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYAD 215
                        250
                 ....*....|....*....
gi 949724212 238 RVLVMYQGEAVETGSVEQI 256
Cdd:COG3638  216 RIIGLRDGRVVFDGPPAEL 234
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
289-565 1.04e-29

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 123.72  E-value: 1.04e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 289 LISLHDPSHVEPQTEQDTVVEGEPILRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGR 368
Cdd:COG4987  309 LNELLDAPPAVTEPAEPAPAPGGPSLELEDVSFRYP---------GAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLA 379
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 369 ALLRLVESQRGEIIFNGQRIDTLAASKlqpLRRDIQFIFQDPY--ASldprqtvgySILEPLRvhgLLQGDAGSKRVAWL 446
Cdd:COG4987  380 LLLRFLDPQSGSITLGGVDLRDLDEDD---LRRRIAVVPQRPHlfDT---------TLRENLR---LARPDATDEELWAA 444
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 447 LERVGL------LPE--HAWRYPH--EFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIa 516
Cdd:COG4987  445 LERVGLgdwlaaLPDglDTWLGEGgrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTV- 523
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 949724212 517 yLFISHDMAVVERIsHRVAVMYLGQIVEIGTRRAVFEnpQHPYTRKLMA 565
Cdd:COG4987  524 -LLITHRLAGLERM-DRILVLEDGRIVEQGTHEELLA--QNGRYRQLYQ 568
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
8-257 1.50e-29

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 117.11  E-value: 1.50e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   8 DASDVLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEVSCDEMLLRRRNRQ 86
Cdd:COG1121    2 MMMPAIELENLTVSYGGRP----VLEDVSLTIPPGEFVAIVGPNGAGKS-TLLkAILGLLPPTSGTVRLFGKPPRRARRR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  87 vielgeqsasqmrhvrgadIAMIFQepMTSLNPVF--TVGEQIAESIRLHQG------ASHEEAMVEAkrmLDQVripEA 158
Cdd:COG1121   77 -------------------IGYVPQ--RAEVDWDFpiTVRDVVLMGRYGRRGlfrrpsRADREAVDEA---LERV---GL 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 159 KAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADR 238
Cdd:COG1121  130 EDLADRPIGELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDR 208
                        250
                 ....*....|....*....
gi 949724212 239 VLVMyQGEAVETGSVEQIF 257
Cdd:COG1121  209 VLLL-NRGLVAHGPPEEVL 226
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
338-543 1.60e-29

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 116.51  E-value: 1.60e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDPYASLDpr 417
Cdd:PRK10908  16 QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMD-- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILEPLRVHGlLQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PRK10908  94 RTVYDNVAIPLIIAG-ASGDDIRRRVSAALDKVGLL-DKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDA 171
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 949724212 498 IRGQIINLMLDLQReLGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:PRK10908 172 LSEGILRLFEEFNR-VGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
339-556 1.62e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 117.93  E-value: 1.62e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaASKLQPLRRDIQFIFQDPyasldPRQ 418
Cdd:PRK13648  24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAIT---DDNFEKLRKHIGIVFQNP-----DNQ 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVG----YSILEPLRVHgLLQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK13648  96 FVGsivkYDVAFGLENH-AVPYDEMHRRVSEALKQVDML-ERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSML 173
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 495 DVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHrVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK13648 174 DPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADH-VIVMNKGTVYKEGTPTEIFDHAE 234
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
14-251 1.63e-29

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 114.84  E-value: 1.63e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  14 AVSNLNIAFeqeQQRVsAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEvscdemllrrrnrqvIELGE 92
Cdd:cd03214    1 EVENLSVGY---GGRT-VLDDLSLSIEAGEIVGILGPNGAGKS-TLLkTLAGLLKPSSGE---------------ILLDG 60
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVRGA-DIAMIFQepmtslnpvftvgeqiaesirlhqgasheeamveakrMLDQVRIpeaKAILSRYPHQLSG 171
Cdd:cd03214   61 KDLASLSPKELArKIAYVPQ-------------------------------------ALELLGL---AHLADRPFNELSG 100
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03214  101 GERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
13-261 3.22e-29

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 116.00  E-value: 3.22e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI----EQAGGEVS-CDEMLLRRRNRQV 87
Cdd:cd03219    1 LEVRGLTKRFGG----LVALDDVSFSVRPGEIHGLIGPNGAGKT----TLFNLIsgflRPTSGSVLfDGEDITGLPPHEI 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  88 IELGeqsasqmrhvrgadIAMIFQEP-----MTSLNPVfTVGEQIA--ESIRLHQGASHEEAMVE-AKRMLDQVRIPEak 159
Cdd:cd03219   73 ARLG--------------IGRTFQIPrlfpeLTVLENV-MVAAQARtgSGLLLARARREEREARErAEELLERVGLAD-- 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 160 aILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRV 239
Cdd:cd03219  136 -LADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRER-GITVLLVEHDMDVVMSLADRV 213
                        250       260
                 ....*....|....*....|..
gi 949724212 240 LVMYQGEAVETGSVEQIFHAPQ 261
Cdd:cd03219  214 TVLDQGRVIAEGTPDEVRNNPR 235
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
336-565 3.66e-29

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 116.61  E-value: 3.66e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAAS----------KLQPLRRDIQF 405
Cdd:PRK10619  17 EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKdgqlkvadknQLRLLRTRLTM 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 406 IFQdpYASLDPRQTVGYSILE-PLRVHGLLQGDAGSKRVAWLlERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKV 484
Cdd:PRK10619  97 VFQ--HFNLWSHMTVLENVMEaPIQVLGLSKQEARERAVKYL-AKVGIDERAQGKYPVHLSGGQQQRVSIARALAMEPEV 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 485 IIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLM 564
Cdd:PRK10619 174 LLFDEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFL 252

                 .
gi 949724212 565 A 565
Cdd:PRK10619 253 K 253
cbiO PRK13650
energy-coupling factor transporter ATPase;
336-552 6.56e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 116.37  E-value: 6.56e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRidtLAASKLQPLRRDIQFIFQDPyasld 415
Cdd:PRK13650  19 EKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDL---LTEENVWDIRHKIGMVFQNP----- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSIlEPLRVHGL----LQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:PRK13650  91 DNQFVGATV-EDDVAFGLenkgIPHEEMKERVNEALELVGMQ-DFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEAT 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 492 SALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVErISHRVAVMYLGQIVEIGTRRAVF 552
Cdd:PRK13650 169 SMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRELF 228
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
9-261 6.88e-29

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 115.52  E-value: 6.88e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFeqeqQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI----EQAGGEVSCD-EMLLRRR 83
Cdd:COG0411    1 SDPLLEVRGLTKRF----GGLVAVDDVSLEVERGEIVGLIGPNGAGKT----TLFNLItgfyRPTSGRILFDgRDITGLP 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  84 NRQVIELGeqsasqmrhvrgadIAMIFQepMTSLNPVFTVGEQIAESIRLHQGAS--------------HEEAMVEAKRM 149
Cdd:COG0411   73 PHRIARLG--------------IARTFQ--NPRLFPELTVLENVLVAAHARLGRGllaallrlprarreEREARERAEEL 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 150 LDQVRIpEAKAilSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDM 229
Cdd:COG0411  137 LERVGL-ADRA--DEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDM 213
                        250       260       270
                 ....*....|....*....|....*....|..
gi 949724212 230 GVVADIADRVLVMYQGEAVETGSVEQIFHAPQ 261
Cdd:COG0411  214 DLVMGLADRIVVLDFGRVIAEGTPAEVRADPR 245
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
343-575 7.05e-29

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 118.29  E-value: 7.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  343 VSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridTLAASK----LQPLRRDIQFIFQDpyASLDPRq 418
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGR---TLFDSRkgifLPPEKRRIGYVFQE--ARLFPH- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  419 tvgYSILEPLRvHGLLQGDAGSKRVAW--LLERVGLlpEHAW-RYPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:TIGR02142  90 ---LSVRGNLR-YGMKRARPSERRISFerVIELLGI--GHLLgRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALD 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  496 VSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRK------LMAAVPV 569
Cdd:TIGR02142 164 DPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPWLARedqgslIEGVVAE 243

                  ....*.
gi 949724212  570 ADPSHH 575
Cdd:TIGR02142 244 HDQHYG 249
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
31-288 7.18e-29

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 118.98  E-value: 7.18e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQSASQMRHVRGADIAMIF 110
Cdd:PRK10070  43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDG----------VDIAKISDAELREVRRKKIAMVF 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEpmTSLNPVFTVGEQIAESIRLHQGASHEEAmveaKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:PRK10070 113 QS--FALMPHMTVLDNTAFGMELAGINAEERR----EKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDIL 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLA 270
Cdd:PRK10070 187 LMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFR 266
                        250
                 ....*....|....*...
gi 949724212 271 AVPQLGAMNGHELPRRFP 288
Cdd:PRK10070 267 GVDISQVFSAKDIARRTP 284
cbiO PRK13637
energy-coupling factor transporter ATPase;
31-257 7.22e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 116.30  E-value: 7.22e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQSASqMRHVRgADIAMIF 110
Cdd:PRK13637  22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDG----------VDITDKKVK-LSDIR-KKVGLVF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMTSLnpvF--TVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEAKaILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK13637  90 QYPEYQL---FeeTIEKDIAFGPI-NLGLSEEEIENRVKRAMNIVGLDYED-YKDKSPFELSGGQKRRVAIAGVVAMEPK 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13637 165 ILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
7-257 7.70e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 117.26  E-value: 7.70e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   7 LDASDVLAVSNLNIAFEQEQ-QRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRR-- 83
Cdd:PRK13631  16 LSDDIILRVKNLYCVFDEKQeNELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKkn 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  84 -NRQVIELGEQSASQMRHVRGAdIAMIFQEPMTSLnpvF--TVGEQIA-ESIRLhqGASHEEAMVEAKRMLDQVRIPEAk 159
Cdd:PRK13631  96 nHELITNPYSKKIKNFKELRRR-VSMVFQFPEYQL---FkdTIEKDIMfGPVAL--GVKKSEAKKLAKFYLNKMGLDDS- 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 160 aILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRV 239
Cdd:PRK13631 169 -YLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEV 246
                        250
                 ....*....|....*...
gi 949724212 240 LVMYQGEAVETGSVEQIF 257
Cdd:PRK13631 247 IVMDKGKILKTGTPYEIF 264
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
34-261 8.56e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 116.27  E-value: 8.56e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRlkRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrQVIElGEQSASQMRHVRgADIAMIFQEP 113
Cdd:PRK13634  27 NVSIP--SGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGE--------RVIT-AGKKNKKLKPLR-KKVGIVFQFP 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 114 MTSLnpvF--TVGEQIAESiRLHQGASHEEAMVEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:PRK13634  95 EHQL---FeeTVEKDICFG-PMNFGVSEEDAKQKAREMIELVGLPEE--LLARSPFELSGGQMRRVAIAGVLAMEPEVLV 168
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQ 261
Cdd:PRK13634 169 LDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
31-256 1.09e-28

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 114.00  E-value: 1.09e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGE-------VSCDEMLLRRRnrqvielgeqsasqmrhvrg 103
Cdd:cd03265   15 AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRatvaghdVVREPREVRRR-------------------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 104 adIAMIFQEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMAL 183
Cdd:cd03265   75 --IGIVFQDL--SVDDELTGWENLYIHARL-YGVPGAERRERIDELLDFVGLLEAA---DRLVKTYSGGMRRRLEIARSL 146
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:cd03265  147 VHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
29-550 1.17e-28

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 120.27  E-value: 1.17e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrNRQVIELGEQSASQMrhvrgaDIAM 108
Cdd:PRK09700  18 VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITIN-------NINYNKLDHKLAAQL------GIGI 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQE-----PMTSLNPVFtVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMAL 183
Cdd:PRK09700  85 IYQElsvidELTVLENLY-IGRHLTKKVCGVNIIDWREMRVRAAMMLLRVGL---KVDLDEKVANLSISHKQMLEIAKTL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 184 SCRPAVLIADEPTTALdvtIQAQILQLIKVLQQDMSMG--VIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIfhapq 261
Cdd:PRK09700 161 MLDAKVIIMDEPTSSL---TNKEVDYLFLIMNQLRKEGtaIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDV----- 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 262 hpYTKALLAAvpqlgaMNGHELPRRFPlislhdpshvePQTEQDTVVEGEPILRVRNLVTRfplrsgilnrvtrEVHAVE 341
Cdd:PRK09700 233 --SNDDIVRL------MVGRELQNRFN-----------AMKENVSNLAHETVFEVRNVTSR-------------DRKKVR 280
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlAASKLQPLRRDIQFIFQDP-----YASLDP 416
Cdd:PRK09700 281 DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIS--PRSPLDAVKKGMAYITESRrdngfFPNFSI 358
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVgySILEPLRVHGL-----LQGDAGSKRVAWLLERVGLLPEHAW-RYPHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:PRK09700 359 AQNM--AISRSLKDGGYkgamgLFHEVDEQRTAENQRELLALKCHSVnQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 491 VSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRA 550
Cdd:PRK09700 437 TRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRD 495
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
312-534 1.38e-28

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 114.14  E-value: 1.38e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFplRSGilnRVTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTL 391
Cdd:PRK11629   4 ILLQCDNLCKRY--QEG---SVQTDV--LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AASKLQPLR-RDIQFIFQdpYASLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQ 470
Cdd:PRK11629  77 SSAAKAELRnQKLGFIYQ--FHHLLPDFTALENVAMPLLIGKKKPAEI-NSRALEMLAAVGL-EHRANHRPSELSGGERQ 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRV 534
Cdd:PRK11629 153 RVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQL 216
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
17-245 1.44e-28

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 113.54  E-value: 1.44e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  17 NLNIAFEQEQQRVSAvrNLSFRLKrGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDEMLLRRRNRQVIelgeqSA 95
Cdd:cd03297    1 MLCVDIEKRLPDFTL--KIDFDLN-EEVTGIFGASGAGKS-TLLRCIAGLEKPdGGTIVLNGTVLFDSRKKIN-----LP 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  96 SQMRHvrgadIAMIFQEpmTSLNPVFTVGEQIAESIRLHqgaSHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSGGMRQ 175
Cdd:cd03297   72 PQQRK-----IGLVFQQ--YALFPHLNVRENLAFGLKRK---RNREDRISVDELLDLLGLDH---LLNRYPAQLSGGEKQ 138
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 176 RVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQG 245
Cdd:cd03297  139 RVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDG 208
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
313-546 1.53e-28

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 113.62  E-value: 1.53e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLrsgilnrVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGqrIDTLA 392
Cdd:cd03266    1 MITADALTKRFRD-------VKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG--FDVVK 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASklQPLRRDIQFIFQDP--YASLDPRQTVGYSIleplRVHGLlQGDAGSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQ 470
Cdd:cd03266   72 EP--AEARRRLGFVSDSTglYDRLTARENLEYFA----GLYGL-KGDELTARLEELADRLGM-EELLDRRVGGFSTGMRQ 143
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRgQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03266  144 KVAIARALVHDPPVLLLDEPTTGLDVMAT-RALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
311-544 1.72e-28

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 119.35  E-value: 1.72e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsGilnrvtreVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDt 390
Cdd:COG1129    2 EPLLEMRGISKSFG---G--------VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVR- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 lAASKLQPLRRDIQFIFQDPyaSLDPRQTVGYSIL---EPLRvHGLLQGDAGSKRVAWLLERVGlLPEHAWRYPHEFSGG 467
Cdd:COG1129   70 -FRSPRDAQAAGIAIIHQEL--NLVPNLSVAENIFlgrEPRR-GGLIDWRAMRRRARELLARLG-LDIDPDTPVGDLSVA 144
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 468 QRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVE 544
Cdd:COG1129  145 QQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVG 220
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
15-242 1.84e-28

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 113.01  E-value: 1.84e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  15 VSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEvscdemllrrrnrqvIELGEQ 93
Cdd:cd03235    2 VEDLTVSYGGHP----VLEDVSFEVKPGEFLAIVGPNGAGKS-TLLkAILGLLKPTSGS---------------IRVFGK 61
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 SASQMRHvrgaDIAMIFQEpmTSLNPVF--TVGEQIA----ESIRLHQGASHEEaMVEAKRMLDQVRIpeaKAILSRYPH 167
Cdd:cd03235   62 PLEKERK----RIGYVPQR--RSIDRDFpiSVRDVVLmglyGHKGLFRRLSKAD-KAKVDEALERVGL---SELADRQIG 131
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVM 242
Cdd:cd03235  132 ELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
29-262 1.94e-28

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 116.71  E-value: 1.94e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAG------GEVSCDemllrrrNRQVIELgeqsasqmrHVR 102
Cdd:COG3839   16 VEALKDIDLDIEDGEFLVLLGPSGCGKS----TLLRMI--AGledptsGEILIG-------GRDVTDL---------PPK 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 103 GADIAMIFQEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSGGMRQRVMIAMA 182
Cdd:COG3839   74 DRNIAMVFQSY--ALYPHMTVYENIAFPLKL-RKVPKAEIDRRVREAAELLGLED---LLDRKPKQLSGGQRQRVALGRA 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 183 LSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHD----MGvvadIADRVLVMYQGEAVETGSVEQIFH 258
Cdd:COG3839  148 LVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveaMT----LADRIAVMNDGRIQQVGTPEELYD 223

                 ....
gi 949724212 259 APQH 262
Cdd:COG3839  224 RPAN 227
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
344-564 2.21e-28

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 113.31  E-value: 2.21e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 344 SFDLW--PGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQRIDTLAasklqPLRRDIQFIFQDP--YASLD 415
Cdd:COG3840   17 RFDLTiaAGERVAILGPSGAGKST----LLNLIagflPPDSGRILWNGQDLTALP-----PAERPVSMLFQENnlFPHLT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILEPLRVhgllqGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:COG3840   88 VAQNIGLGLRPGLKL-----TAEQRAQVEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALD 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 496 VSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLM 564
Cdd:COG3840  162 PALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYL 230
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
342-555 3.74e-28

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 115.97  E-value: 3.74e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRI-DTLAASKLQPLRRDIQFIFQDpyASLDPRQTV 420
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqDSARGIFLPPHRRRIGYVFQE--ARLFPHLSV 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 421 gysiLEPLRvHGLLQGDAGSKRVAW--LLERVGLLPeHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSI 498
Cdd:COG4148   95 ----RGNLL-YGRKRAPRAERRISFdeVVELLGIGH-LLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLAR 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 499 RGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENP 555
Cdd:COG4148  169 KAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
339-556 4.56e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 113.55  E-value: 4.56e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridTLAASKLQPLRRDIQFIFQDPyasldPRQ 418
Cdd:PRK13632  24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGI---TISKENLKEIRKKIGIIFQNP-----DNQ 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSI-------LEPLRVhgllQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:PRK13632  96 FIGATVeddiafgLENKKV----PPKKMKDIIDDLAKKVGME-DYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDEST 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 492 SALDVSIRGQIINLMLDLQRELGIAYLFISHDMAvvERI-SHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK13632 171 SMLDPKGKREIKKIMVDLRKTRKKTLISITHDMD--EAIlADKVIVFSEGKLIAQGKPKEILNNKE 234
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
4-255 4.67e-28

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 118.71  E-value: 4.67e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   4 SDELDASDVLAVSNLNIAFEQEQQrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrr 83
Cdd:COG4988  328 PLPAAGPPSIELEDVSFSYPGGRP---ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILING------ 398
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  84 nrqvIELGEQSASQMRhvrgADIAMIFQEPmtslnpvFTVGEQIAESIRLHQGASHEEAMVEAkrmLDQVRIPEakaILS 163
Cdd:COG4988  399 ----VDLSDLDPASWR----RQIAWVPQNP-------YLFAGTIRENLRLGRPDASDEELEAA---LEAAGLDE---FVA 457
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 164 RYPH-----------QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVV 232
Cdd:COG4988  458 ALPDgldtplgeggrGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRT--VILITHRLALL 535
                        250       260
                 ....*....|....*....|...
gi 949724212 233 ADiADRVLVMYQGEAVETGSVEQ 255
Cdd:COG4988  536 AQ-ADRILVLDDGRIVEQGTHEE 557
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
318-555 4.93e-28

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 115.57  E-value: 4.93e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 318 NLVTRFPLRSGILNrvtrevhaveNVSFDLWPGETLSLVGESGCGKSTtgraLLRLV---ESQR-GEIIFNGQRIdtlaa 393
Cdd:PRK10851   6 ANIKKSFGRTQVLN----------DISLDIPSGQMVALLGPSGSGKTT----LLRIIaglEHQTsGHIRFHGTDV----- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQPLRRDIQFIFQDpYAsLDPRQTVGYSILEPLRV---HGLLQGDAGSKRVAWLLERVGLlpEH-AWRYPHEFSGGQR 469
Cdd:PRK10851  67 SRLHARDRKVGFVFQH-YA-LFRHMTVFDNIAFGLTVlprRERPNAAAIKAKVTQLLEMVQL--AHlADRYPAQLSGGQK 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:PRK10851 143 QRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPD 222

                 ....*.
gi 949724212 550 AVFENP 555
Cdd:PRK10851 223 QVWREP 228
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
338-537 5.15e-28

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 111.86  E-value: 5.15e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridtlaasKLQPLRRDIQFIFQ----DPYAS 413
Cdd:cd03235   13 PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK--------PLEKERKRIGYVPQrrsiDRDFP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDPRQTVGYSILEPLRVHGLLqGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSA 493
Cdd:cd03235   85 ISVRDVVLMGLYGHKGLFRRL-SKADKAKVDEALERVGLS-ELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAG 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 949724212 494 LDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVM 537
Cdd:cd03235  163 VDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDRVLLL 205
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
13-264 1.00e-27

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 114.75  E-value: 1.00e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   13 LAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGE 92
Cdd:TIGR03265   5 LSIDNIRKRFGA----FTALKDISLSVKKGEFVCLLGPSGCGKT----TLLRII--AG---------LERQTAGTIYQGG 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   93 QSAS----QMRhvrgaDIAMIFQEpmTSLNPVFTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQ 168
Cdd:TIGR03265  66 RDITrlppQKR-----DYGIVFQS--YALFPNLTVADNIAYGLK-NRGMGRAEVAERVAELLDLVGLPGSE---RKYPGQ 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAV 248
Cdd:TIGR03265 135 LSGGQQQRVALARALATSPGLLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIE 214
                         250
                  ....*....|....*.
gi 949724212  249 ETGSVEQIFHAPQHPY 264
Cdd:TIGR03265 215 QVGTPQEIYRHPATPF 230
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
340-525 1.04e-27

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 111.03  E-value: 1.04e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRAL---LRLVESQRGEIIFNGQRIDTlaaskLQPLRRDIQFIFQDPYasLDP 416
Cdd:COG4136   17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIagtLSPAFSASGEVLLNGRRLTA-----LPAEQRRIGILFQDDL--LFP 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYSILEPLRVHglLQGDAGSKRVAWLLERVGlLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:COG4136   90 HLSVGENLAFALPPT--IGRAQRRARVEQALEEAG-LAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDA 166
                        170       180
                 ....*....|....*....|....*....
gi 949724212 497 SIRGQIINLMLDLQRELGIAYLFISHDMA 525
Cdd:COG4136  167 ALRAQFREFVFEQIRQRGIPALLVTHDEE 195
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
12-242 1.20e-27

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 111.37  E-value: 1.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAF---EQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI-----EQAGgevscdEMLLRRR 83
Cdd:COG4778    4 LLEVENLSKTFtlhLQGGKRLPVLDGVSFSVAAGECVALTGPSGAGKS----TLLKCIygnylPDSG------SILVRHD 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  84 NrQVIELGEQSASQMRHVRGADIAMIFQepmtSLNPVFTVG--EQIAESIrLHQGASHEEAMVEAKRMLDQVRIPEAKAI 161
Cdd:COG4778   74 G-GWVDLAQASPREILALRRRTIGYVSQ----FLRVIPRVSalDVVAEPL-LERGVDREEARARARELLARLNLPERLWD 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 162 LsrYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLV 241
Cdd:COG4778  148 L--PPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVD 224

                 .
gi 949724212 242 M 242
Cdd:COG4778  225 V 225
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
34-272 1.43e-27

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 111.34  E-value: 1.43e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDEMLLRRRNRQVielgeqsasqmRHVRgADIAMIFQE 112
Cdd:PRK09493  19 NIDLNIDQGEVVVIIGPSGSGKS-TLLRCINKLEEiTSGDLIVDGLKVNDPKVDE-----------RLIR-QEAGMVFQQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 113 pmTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVLIA 192
Cdd:PRK09493  86 --FYLFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAERA---HHYPSELSGGQQQRVAIARALAVKPKLMLF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 193 DEPTTALDVTIQAQILQLIKVLQQD-MSMgvIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLAA 271
Cdd:PRK09493 161 DEPTSALDPELRHEVLKVMQDLAEEgMTM--VIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFLQH 238

                 .
gi 949724212 272 V 272
Cdd:PRK09493 239 V 239
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
314-551 1.55e-27

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 110.60  E-value: 1.55e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03224    1 LEVENLNAGY-----------GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPP 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLqpLRRDIQFIFQDPyaSLDPRQTVgysiLEPLRVHGLLQGDAGSK-RVAWLLERVGLLPEHAWRYPHEFSGGQRQRI 472
Cdd:cd03224   70 HER--ARAGIGYVPEGR--RIFPELTV----EENLLLGAYARRRAKRKaRLERVYELFPRLKERRKQLAGTLSGGEQQML 141
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 473 CIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:cd03224  142 AIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIREL-RDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
313-556 1.72e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 112.09  E-value: 1.72e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSGILNrvtrevhaveNVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLA 392
Cdd:PRK13639   1 ILETRDLKYSYPDGTEALK----------GINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDK 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLQpLRRDIQFIFQDPYASL-DPR--QTVGYSilePLRVHglLQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQR 469
Cdd:PRK13639  71 KSLLE-VRKTVGIVFQNPDDQLfAPTveEDVAFG---PLNLG--LSKEEVEKRVKEALKAVGME-GFENKPPHHLSGGQK 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:PRK13639 144 KRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPK 222

                 ....*..
gi 949724212 550 AVFENPQ 556
Cdd:PRK13639 223 EVFSDIE 229
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
23-275 3.52e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 111.33  E-value: 3.52e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  23 EQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrnrqvielgeqSASQMRHVr 102
Cdd:PRK13633  17 NEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGL---------------DTSDEENL- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 103 gADI----AMIFQEPMTSLnpVFT-VGEQIA---ESIrlhqGASHEEAMVEAKRMLDQVRIPEAKailsRY-PHQLSGGM 173
Cdd:PRK13633  81 -WDIrnkaGMVFQNPDNQI--VATiVEEDVAfgpENL----GIPPEEIRERVDESLKKVGMYEYR----RHaPHLLSGGQ 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 174 RQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADiADRVLVMYQGEAVETGSV 253
Cdd:PRK13633 150 KQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTP 228
                        250       260
                 ....*....|....*....|..
gi 949724212 254 EQIFhaPQHPYTKALLAAVPQL 275
Cdd:PRK13633 229 KEIF--KEVEMMKKIGLDVPQV 248
cbiO PRK13642
energy-coupling factor transporter ATPase;
12-287 3.56e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 111.34  E-value: 3.56e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQrVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielG 91
Cdd:PRK13642   4 ILEVENLVFKYEKESD-VNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKID--------------G 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQ-SASQMRHVRgADIAMIFQEPMTSLnpvftVGEQIAESIRL---HQGASHEEAMVEAKRMLDQVRIPEAKailSRYPH 167
Cdd:PRK13642  69 ELlTAENVWNLR-RKIGMVFQNPDNQF-----VGATVEDDVAFgmeNQGIPREEMIKRVDEALLAVNMLDFK---TREPA 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADiADRVLVMYQGEA 247
Cdd:PRK13642 140 RLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEI 218
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 949724212 248 VETGSVEQIFHAPQH--------PYTKALLAAVpqlgAMNGHELPRRF 287
Cdd:PRK13642 219 IKEAAPSELFATSEDmveigldvPFSSNLMKDL----RKNGFDLPEKY 262
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
340-562 4.19e-27

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 110.52  E-value: 4.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE------SQRGEIIFNGQRIDTLAASKLqplRRDIQFIFQDPYAS 413
Cdd:PRK14246  26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIFQIDAIKL---RKEVGMVFQQPNPF 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 ldPRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRY---PHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:PRK14246 103 --PHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLMDEP 180
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 491 VSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRK 562
Cdd:PRK14246 181 TSMIDIVNSQAIEKLITELKNEIAI--VIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEK 250
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
31-253 5.30e-27

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 109.13  E-value: 5.30e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRGaDIAMIF 110
Cdd:cd03263   17 AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYIN--------------GYSIRTDRKAARQ-SLGYCP 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMtsLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:cd03263   82 QFDA--LFDELTVREHLRFYARLK-GLPKSEIKEEVELLLRVLGLTDKA---NKRARTLSGGMKRKLSLAIALIGGPSVL 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIADRVLVMYQGEAVETGSV 253
Cdd:cd03263  156 LLDEPTSGLDPASRRAIWDLILEVRKGRS--IILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
19-269 5.36e-27

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 109.46  E-value: 5.36e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAvrnlSFRLKRGETLAIVGESGSGKSvtalSLMHLI----EQAGGEVSCDemllrrrnrqvielGEQS 94
Cdd:COG3840    6 DLTYRYGDFPLRF----DLTIAAGERVAILGPSGAGKS----TLLNLIagflPPDSGRILWN--------------GQDL 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  95 ASQMRHVRGadIAMIFQEpmTSLNPVFTVGEQIAESIR--LHQGASHEEAMVEAkrmLDQVRIpeaKAILSRYPHQLSGG 172
Cdd:COG3840   64 TALPPAERP--VSMLFQE--NNLFPHLTVAQNIGLGLRpgLKLTAEQRAQVEQA---LERVGL---AGLLDRLPGQLSGG 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGS 252
Cdd:COG3840  134 QRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGP 213
                        250
                 ....*....|....*..
gi 949724212 253 VEQIFHAPQHPYTKALL 269
Cdd:COG3840  214 TAALLDGEPPPALAAYL 230
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
340-555 5.54e-27

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 112.51  E-value: 5.54e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQplRRDIQFIFQDpYAsLDPRQT 419
Cdd:PRK11432  22 IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV---THRSIQ--QRDICMVFQS-YA-LFPHMS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR 499
Cdd:PRK11432  95 LGENVGYGLKMLGVPKEER-KQRVKEALELVDL-AGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLR 172
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 500 GQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENP 555
Cdd:PRK11432 173 RSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQP 228
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
29-566 6.33e-27

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 114.72  E-value: 6.33e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEqagGEVSCDEMLLRRRNRQVIELGEQSASQmrhvrgADIAM 108
Cdd:PRK10762  17 VKALSGAALNVYPGRVMALVGENGAGKS----TMMKVLT---GIYTRDAGSILYLGKEVTFNGPKSSQE------AGIGI 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEpmtsLN--PVFTvgeqIAESIRLHQGASHEEAMVEAKRMLDqvripEAKAILSRY-----PHQLSG----GMRQRV 177
Cdd:PRK10762  84 IHQE----LNliPQLT----IAENIFLGREFVNRFGRIDWKKMYA-----EADKLLARLnlrfsSDKLVGelsiGEQQMV 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 178 MIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIf 257
Cdd:PRK10762 151 EIAKVLSFESKVIIMDEPTDALTDTETESLFRVIREL-KSQGRGIVYISHRLKEIFEICDDVTVFRDGQFIAEREVADL- 228
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 258 hapqhpyTKALLaavpqLGAMNGHELPRRFPLISlhdpshvepqteqdtVVEGEPILRVRNLvtrfplrSGilnrvtrev 337
Cdd:PRK10762 229 -------TEDSL-----IEMMVGRKLEDQYPRLD---------------KAPGEVRLKVDNL-------SG--------- 265
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTlaASKLQPLRRDIQFIFQDpyasldpR 417
Cdd:PRK10762 266 PGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVT--RSPQDGLANGIVYISED-------R 336
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 Q----TVGYSILEPL---------RVHGLLQGDAGSKRVAWLLE-----------RVGLLpehawryphefSGGQRQRIC 473
Cdd:PRK10762 337 KrdglVLGMSVKENMsltalryfsRAGGSLKHADEQQAVSDFIRlfniktpsmeqAIGLL-----------SGGNQQKVA 405
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 474 IARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIV-EIGTRRAVF 552
Cdd:PRK10762 406 IARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRISgEFTREQATQ 484
                        570
                 ....*....|....
gi 949724212 553 EnpqhpytrKLMAA 566
Cdd:PRK10762 485 E--------KLMAA 490
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
19-256 8.29e-27

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 115.70  E-value: 8.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGEQSASQM 98
Cdd:COG2274  478 NVSFRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKS----TLLKLL--LG---------LYEPTSGRILIDGIDLRQI 542
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 --RHVRgADIAMIFQEPMtslnpVF--TvgeqIAESIRLHQGASHEEAMVEAKRMLdqvripEAKAILSRYPH------- 167
Cdd:COG2274  543 dpASLR-RQIGVVLQDVF-----LFsgT----IRENITLGDPDATDEEIIEAARLA------GLHDFIEALPMgydtvvg 606
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 ----QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMY 243
Cdd:COG2274  607 eggsNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRT--VIIIAHRLSTIRL-ADRIIVLD 683
                        250
                 ....*....|...
gi 949724212 244 QGEAVETGSVEQI 256
Cdd:COG2274  684 KGRIVEDGTHEEL 696
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
334-547 1.07e-26

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 108.78  E-value: 1.07e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 334 TR-EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAaskLQPLRRDIQFIFQDP-- 410
Cdd:cd03249   12 SRpDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLN---LRWLRSQIGLVSQEPvl 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 411 -YASLdpRQTVGYSILEPLRVHgllqgDAGSKRVAWLLERVGLLPEhawRY-----PH--EFSGGQRQRICIARALALNP 482
Cdd:cd03249   89 fDGTI--AENIRYGKPDATDEE-----VEEAAKKANIHDFIMSLPD---GYdtlvgERgsQLSGGQKQRIAIARALLRNP 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 483 KVIIADESVSALDvSIRGQIINLMLDLQRElGIAYLFISHDMAVVeRISHRVAVMYLGQIVEIGT 547
Cdd:cd03249  159 KILLLDEATSALD-AESEKLVQEALDRAMK-GRTTIVIAHRLSTI-RNADLIAVLQNGQVVEQGT 220
cbiO PRK13646
energy-coupling factor transporter ATPase;
31-257 1.20e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 109.87  E-value: 1.20e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQvielgeqsaSQMRHVRgADIAMIF 110
Cdd:PRK13646  22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKD---------KYIRPVR-KRIGMVF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMTSLnpvF--TVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPeaKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK13646  92 QFPESQL---FedTVEREIIFGPK-NFKMNLDEVKNYAHRLLMDLGFS--RDVMSQSPFQMSGGQMRKIAIVSILAMNPD 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13646 166 IIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
13-242 1.30e-26

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 109.18  E-value: 1.30e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDemllrrrnrqvielG 91
Cdd:COG4525    4 LTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKT-TLLNLIAgFLAPSSGEITLD--------------G 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQmrhvrGADIAMIFQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSG 171
Cdd:COG4525   69 VPVTGP-----GADRGVVFQK--DALLPWLNVLDNVAFGLRL-RGVPKAERRARAEELLALVGLADFA---RRRIWQLSG 137
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVM 242
Cdd:COG4525  138 GMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVM 208
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
9-270 1.46e-26

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 108.90  E-value: 1.46e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIE---QAGGEVSCDEMLLRRRNR 85
Cdd:PRK10619   2 SENKLNVIDLHKRYGEHE----VLKGVSLQANAGDVISIIGSSGSGKS-TFLRCINFLEkpsEGSIVVNGQTINLVRDKD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  86 QVIELGEQSASQMRHVRgadIAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAIlsRY 165
Cdd:PRK10619  77 GQLKVADKNQLRLLRTR---LTMVFQH--FNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQG--KY 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 166 PHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIfITHDMGVVADIADRVLVMYQG 245
Cdd:PRK10619 150 PVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVV-VTHEMGFARHVSSHVIFLHQG 228
                        250       260
                 ....*....|....*....|....*
gi 949724212 246 EAVETGSVEQIFHAPQHPYTKALLA 270
Cdd:PRK10619 229 KIEEEGAPEQLFGNPQSPRLQQFLK 253
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
30-257 1.51e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 109.40  E-value: 1.51e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  30 SAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIElgeqsasqmrhVRgADIAMI 109
Cdd:PRK13639  16 EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSLLE-----------VR-KTVGIV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEPMTSL-NPvfTVGEQIAESiRLHQGASHEEamVEaKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK13639  84 FQNPDDQLfAP--TVEEDVAFG-PLNLGLSKEE--VE-KRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPE 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13639 158 IIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVF 225
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
12-256 1.97e-26

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 108.15  E-value: 1.97e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   12 VLAVSNLNIAFEQEQQrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrnrqviELG 91
Cdd:TIGR02315   1 MLEVENLSKVYPNGKQ---ALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGT----------DIT 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   92 EQSASQMRHVRgADIAMIFQE-----PMTSLNPVFT--VGEQiaESIRLHQGASHEEAMVEAKRMLDQVRIpeAKAILSR 164
Cdd:TIGR02315  68 KLRGKKLRKLR-RRIGMIFQHynlieRLTVLENVLHgrLGYK--PTWRSLLGRFSEEDKERALSALERVGL--ADKAYQR 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  165 yPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQ 244
Cdd:TIGR02315 143 -ADQLSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKA 221
                         250
                  ....*....|..
gi 949724212  245 GEAVETGSVEQI 256
Cdd:TIGR02315 222 GEIVFDGAPSEL 233
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
334-554 2.12e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 109.02  E-value: 2.12e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 334 TREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGqrIDTLAASKLQPLRRDIQFIFQDPyas 413
Cdd:PRK13633  20 STEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG--LDTSDEENLWDIRNKAGMVFQNP--- 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 ldPRQTVGySILEPLRVHGL----LQGDAGSKRVAWLLERVGLlpehaWRY----PHEFSGGQRQRICIARALALNPKVI 485
Cdd:PRK13633  95 --DNQIVA-TIVEEDVAFGPenlgIPPEEIRERVDESLKKVGM-----YEYrrhaPHLLSGGQKQRVAIAGILAMRPECI 166
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 486 IADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDM-AVVEriSHRVAVMYLGQIVEIGTRRAVFEN 554
Cdd:PRK13633 167 IFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMeEAVE--ADRIIVMDSGKVVMEGTPKEIFKE 234
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
335-546 2.49e-26

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 106.98  E-value: 2.49e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 335 REVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDiqfifqdpyASL 414
Cdd:cd03269   11 GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNRIGYLPEE---------RGL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGlLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:cd03269   82 YPKMKVIDQLVYLAQLKGLKKEEA-RRRIDEWLERLE-LSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 949724212 495 DVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03269  160 DPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
31-264 3.01e-26

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 110.96  E-value: 3.01e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKS--VTALSLmhLIEQAGGEVSCDEmllrrrnrqvIELGEQSASQMRHVRGADIAM 108
Cdd:COG4175   42 GVNDASFDVEEGEIFVIMGLSGSGKStlVRCLNR--LIEPTAGEVLIDG----------EDITKLSKKELRELRRKKMSM 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEpmtslnpvF------TVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRipeakaiLS----RYPHQLSGGMRQRVM 178
Cdd:COG4175  110 VFQH--------FallphrTVLENVAFGLEI-QGVPKAERRERAREALELVG-------LAgwedSYPDELSGGMQQRVG 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 179 IAMALSCRPAVLIADEPTTALDVTIQAQiLQ--LIKvLQQDMSMGVIFITHDMgvvaD----IADRVLVMYQGEAVETGS 252
Cdd:COG4175  174 LARALATDPDILLMDEAFSALDPLIRRE-MQdeLLE-LQAKLKKTIVFITHDL----DealrLGDRIAIMKDGRIVQIGT 247
                        250
                 ....*....|..
gi 949724212 253 VEQIFHAPQHPY 264
Cdd:COG4175  248 PEEILTNPANDY 259
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
2-270 3.41e-26

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 113.32  E-value: 3.41e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   2 PHSDELDASDVLAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllr 81
Cdd:COG4987  323 AEPAPAPGGPSLELEDVSFRYPGAGRPV--LDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGG---- 396
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  82 rrnrqvIELGEQSASQMRHVrgadIAMIFQEPmtslnPVF--TvgeqIAESIRLHQGASHEEAMVEAkrmLDQVRIPEak 159
Cdd:COG4987  397 ------VDLRDLDEDDLRRR----IAVVPQRP-----HLFdtT----LRENLRLARPDATDEELWAA---LERVGLGD-- 452
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 160 aILSRYPH-----------QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHD 228
Cdd:COG4987  453 -WLAALPDgldtwlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRT--VLLITHR 529
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 949724212 229 MgVVADIADRVLVMYQGEAVETGSVEQIfhAPQHPYTKALLA 270
Cdd:COG4987  530 L-AGLERMDRILVLEDGRIVEQGTHEEL--LAQNGRYRQLYQ 568
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
31-260 3.48e-26

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 109.02  E-value: 3.48e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLM-HLIEQAGGEV--------SCDEMLLRRRNRQVIelgeQSASqmrhv 101
Cdd:COG1125   17 AVDDLSLTIPAGEFTVLVGPSGCGKT-TTLRMInRLIEPTSGRIlidgedirDLDPVELRRRIGYVI----QQIG----- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 102 rgadiamifqepmtsLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPeAKAILSRYPHQLSGGMRQRVMIAM 181
Cdd:COG1125   87 ---------------LFPHMTVAENIATVPRL-LGWDKERIRARVDELLELVGLD-PEEYRDRYPHELSGGQQQRVGVAR 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMgvvaD----IADRVLVMYQGEAVETGSVEQIF 257
Cdd:COG1125  150 ALAADPPILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDI----DealkLGDRIAVMREGRIVQYDTPEEIL 225

                 ...
gi 949724212 258 HAP 260
Cdd:COG1125  226 ANP 228
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
13-256 3.75e-26

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 107.27  E-value: 3.75e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGE 92
Cdd:cd03256    1 IEVENLSKTYPNGKK---ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDG----------TDINK 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVRgADIAMIFQEPmtSLNPVFTVGEQIAeSIRLHQ--------GASHEEAMVEAKRMLDQVRIPEaKAilSR 164
Cdd:cd03256   68 LKGKALRQLR-RQIGMIFQQF--NLIERLSVLENVL-SGRLGRrstwrslfGLFPKEEKQRALAALERVGLLD-KA--YQ 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 165 YPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQ 244
Cdd:cd03256  141 RADQLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKD 220
                        250
                 ....*....|..
gi 949724212 245 GEAVETGSVEQI 256
Cdd:cd03256  221 GRIVFDGPPAEL 232
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
29-256 5.79e-26

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 112.20  E-value: 5.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVScdemllrrrnrqvIELGEQSASQMRhvRGAD--- 105
Cdd:TIGR03269 297 VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVN-------------VRVGDEWVDMTK--PGPDgrg 361
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  106 -----IAMIFQEpmTSLNPVFTVGEQIAESIRLHqgASHEEAMVEAKRMLDQVRIPEAKA--ILSRYPHQLSGGMRQRVM 178
Cdd:TIGR03269 362 rakryIGILHQE--YDLYPHRTVLDNLTEAIGLE--LPDELARMKAVITLKMVGFDEEKAeeILDKYPDELSEGERHRVA 437
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212  179 IAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:TIGR03269 438 LAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
cbiO PRK13642
energy-coupling factor transporter ATPase;
313-564 6.83e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 107.49  E-value: 6.83e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRidtLA 392
Cdd:PRK13642   4 ILEVENLVFKYEKES--------DVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGEL---LT 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLQPLRRDIQFIFQDPyasldPRQTVGYSILEPLRVHGLLQG---DAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQR 469
Cdd:PRK13642  73 AENVWNLRRKIGMVFQNP-----DNQFVGATVEDDVAFGMENQGiprEEMIKRVDEALLAVNML-DFKTREPARLSGGQK 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGTRR 549
Cdd:PRK13642 147 QRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPS 225
                        250       260
                 ....*....|....*....|...
gi 949724212 550 AVFENPQH--------PYTRKLM 564
Cdd:PRK13642 226 ELFATSEDmveigldvPFSSNLM 248
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
337-555 7.17e-26

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 109.16  E-value: 7.17e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 337 VHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV---ES-QRGEIIFNGQRIDTLaasklQPLRRDIQFIFQDpYA 412
Cdd:PRK11650  17 TQVIKGIDLDVADGEFIVLVGPSGCGKST----LLRMVaglERiTSGEIWIGGRVVNEL-----EPADRDIAMVFQN-YA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 sLDPRQTV----GYSilepLRVHGLLQGDAgSKRV---AWLLERVGLLPehawRYPHEFSGGQRQRICIARALALNPKVI 485
Cdd:PRK11650  87 -LYPHMSVrenmAYG----LKIRGMPKAEI-EERVaeaARILELEPLLD----RKPRELSGGQRQRVAMGRAIVREPAVF 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 486 IADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMavVE--RISHRVAVMYLGQIVEIGTRRAVFENP 555
Cdd:PRK11650 157 LFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQ--VEamTLADRVVVMNGGVAEQIGTPVEVYEKP 226
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
312-523 7.19e-26

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 107.26  E-value: 7.19e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPLRSGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTL 391
Cdd:COG4525    2 SMLTVRHVSVRYPGGGQ-------PQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGP 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AAsklqplrrDIQFIFQDpyASLDPRQTVGYSILEPLRVHGLlqGDAGSKRVA-WLLERVGLlPEHAWRYPHEFSGGQRQ 470
Cdd:COG4525   75 GA--------DRGVVFQK--DALLPWLNVLDNVAFGLRLRGV--PKAERRARAeELLALVGL-ADFARRRIWQLSGGMRQ 141
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 949724212 471 RICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHD 523
Cdd:COG4525  142 RVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS 194
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
31-256 7.43e-26

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 108.25  E-value: 7.43e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGevscdemllrrrnrQVIELGEQSASQMRHVRgADIAMIF 110
Cdd:TIGR01188   8 AVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSG--------------TARVAGYDVVREPRKVR-RSIGIVP 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  111 QEPmtSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:TIGR01188  73 QYA--SVDEDLTGRENLEMMGRL-YGLPKDEAEERAEELLELFELGEAA---DRPVGTYSGGMRRRLDIAASLIHQPDVL 146
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212  191 IADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:TIGR01188 147 FLDEPTTGLDPRTRRAIWDYIRALKEE-GVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEEL 211
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
5-252 8.54e-26

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 111.98  E-value: 8.54e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   5 DELDASDVLAVSNL----NIAFEQEQQRvSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLI-EQAGGEVSCDEML 79
Cdd:PRK13657 321 DPPGAIDLGRVKGAvefdDVSFSYDNSR-QGVEDVSFEAKPGQTVAIVGPTGAGKS-TLINLLQRVfDPQSGRILIDGTD 398
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  80 LRRRNRQvielgeqsasQMRHvrgaDIAMIFQEPMTsLNpvftvgEQIAESIRL-HQGASHEEAMVEAKRmldqvriPEA 158
Cdd:PRK13657 399 IRTVTRA----------SLRR----NIAVVFQDAGL-FN------RSIEDNIRVgRPDATDEEMRAAAER-------AQA 450
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 159 KAILSRYPH-----------QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVifITH 227
Cdd:PRK13657 451 HDFIERKPDgydtvvgergrQLSGGERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFI--IAH 528
                        250       260
                 ....*....|....*....|....*
gi 949724212 228 DMGVVADiADRVLVMYQGEAVETGS 252
Cdd:PRK13657 529 RLSTVRN-ADRILVFDNGRVVESGS 552
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
31-246 1.01e-25

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 103.48  E-value: 1.01e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrrrnrqvielgeqsasqmrHVRGADIAmif 110
Cdd:cd00267   14 ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEI--------------------------LIDGKDIA--- 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 qepmtslnpvftvgeqiaesirlhqgasheeamveakrmldQVRIPEAKAILSrYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:cd00267   65 -----------------------------------------KLPLEELRRRIG-YVPQLSGGQRQRVALARALLLNPDLL 102
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd00267  103 LLDEPTSGLDPASRERLLELLRELAEEGRT-VIIVTHDPELAELAADRVIVLKDGK 157
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
311-556 1.10e-25

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 105.83  E-value: 1.10e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDT 390
Cdd:COG0410    1 MPMLEVENLHAGYG-----------GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITG 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LAASKLqpLRRDIQF------IFqdpyasldPRQTVgysiLEPLRVHGLLQGDAgsKRVAWLLERV-GLLP---EHAWRY 460
Cdd:COG0410   70 LPPHRI--ARLGIGYvpegrrIF--------PSLTV----EENLLLGAYARRDR--AEVRADLERVyELFPrlkERRRQR 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 461 PHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLG 540
Cdd:COG0410  134 AGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVLERG 212
                        250
                 ....*....|....*.
gi 949724212 541 QIVEIGTRRAVFENPQ 556
Cdd:COG0410  213 RIVLEGTAAELLADPE 228
PhnT TIGR03258
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...
32-277 1.23e-25

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.


Pssm-ID: 132302 [Multi-domain]  Cd Length: 362  Bit Score: 108.93  E-value: 1.23e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVScdemllrrrnrqvIELGEQSASQMR-HVRGadIAMIF 110
Cdd:TIGR03258  21 LDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAAGLTGR-------------IAIADRDLTHAPpHKRG--LALLF 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  111 QEpmTSLNPVFTVGEQIAESIRlhqgASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:TIGR03258  86 QN--YALFPHLKVEDNVAFGLR----AQKMPKADIAERVADALKLVGLGDAAAHLPAQLSGGMQQRIAIARAIAIEPDVL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  191 IADEPTTALDVTIQAQILQLIKVLQQDM-SMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALL 269
Cdd:TIGR03258 160 LLDEPLSALDANIRANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFL 239

                  ....*...
gi 949724212  270 AAVPQLGA 277
Cdd:TIGR03258 240 GAANILPA 247
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
36-260 1.46e-25

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 108.26  E-value: 1.46e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  36 SFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAG------GEVSCDEMLL----RRRNRQVielgeqsasqmrHVRGad 105
Cdd:COG4148   19 DFTLPGRGVTALFGPSGSGKT----TLLRAI--AGlerpdsGRIRLGGEVLqdsaRGIFLPP------------HRRR-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 IAMIFQEPmtSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDqvrIpeaKAILSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:COG4148   79 IGYVFQEA--RLFPHLSVRGNLLYGRKRAPRAERRISFDEVVELLG---I---GHLLDRRPATLSGGERQRVAIGRALLS 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 186 RPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:COG4148  151 SPRLLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
31-256 2.18e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 106.73  E-value: 2.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVI-----ElgeqsasqmrhvRGad 105
Cdd:COG4152   16 AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRRRIgylpeE------------RG-- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 iamifqepmtsLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPE--AKAIlsrypHQLSGGMRQRVMIAMAL 183
Cdd:COG4152   82 -----------LYPKMKVGEQLVYLARLK-GLSKAEAKRRADEWLERLGLGDraNKKV-----EELSKGNQQKVQLIAAL 144
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 184 SCRPAVLIADEPTTALDVtIQAQILQliKVLQQDMSMG--VIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:COG4152  145 LHDPELLILDEPFSGLDP-VNVELLK--DVIRELAAKGttVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI 216
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
47-279 2.30e-25

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 107.19  E-value: 2.30e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   47 IVGESGSGKSVTALSLMHLIEQAGGEvscdemllrrrnrqvIELGEQSASQM-RHVRGadIAMIFQEpmTSLNPVFTVGE 125
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGS---------------IMLDGEDVTNVpPHLRH--INMVFQS--YALFPHMTVEE 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  126 QIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQA 205
Cdd:TIGR01187  62 NVAFGLKM-RKVPRAEIKPRVLEALRLVQLEEFA---DRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRD 137
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212  206 QILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYTKALLAAVPQLGAMN 279
Cdd:TIGR01187 138 QMQLELKTIQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATV 211
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
312-566 2.82e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 105.50  E-value: 2.82e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPlrsgilnrvTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ-----RGEIIFNGQ 386
Cdd:PRK14258   6 PAIKVNNLSFYYD---------TQKI--LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELEsevrvEGRVEFFNQ 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDTLAASkLQPLRRDIQFIFQDPYasldprqtvgysiLEPLRVHGLLQgdAGSKRVAWL--LERVGLLpEHA------W 458
Cdd:PRK14258  75 NIYERRVN-LNRLRRQVSMVHPKPN-------------LFPMSVYDNVA--YGVKIVGWRpkLEIDDIV-ESAlkdadlW 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 459 --------RYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLM--LDLQRELGIayLFISHDMAVVE 528
Cdd:PRK14258 138 deikhkihKSALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIqsLRLRSELTM--VIVSHNLHQVS 215
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 949724212 529 RISHRVAVMY-----LGQIVEIGTRRAVFENPQHPYTRKLMAA 566
Cdd:PRK14258 216 RLSDFTAFFKgnenrIGQLVEFGLTKKIFNSPHDSRTREYVLS 258
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
11-266 2.90e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 104.99  E-value: 2.90e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  11 DVLAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIE-----QAGGEV--------SCDE 77
Cdd:PRK14247   2 NKIEIRDLKVSFGQ----VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIElypeaRVSGEVyldgqdifKMDV 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  78 MLLRRRnrqvielgeqsasqmrhvrgadIAMIFQEPmtslNPV--FTVGEQIAESIRLHQGA-SHEEAMVEAKRMLDQVR 154
Cdd:PRK14247  78 IELRRR----------------------VQMVFQIP----NPIpnLSIFENVALGLKLNRLVkSKKELQERVRWALEKAQ 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 155 I-PEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVA 233
Cdd:PRK14247 132 LwDEVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMT--IVLVTHFPQQAA 209
                        250       260       270
                 ....*....|....*....|....*....|...
gi 949724212 234 DIADRVLVMYQGEAVETGSVEQIFHAPQHPYTK 266
Cdd:PRK14247 210 RISDYVAFLYKGQIVEWGPTREVFTNPRHELTE 242
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
31-246 3.16e-25

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 102.46  E-value: 3.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRqvielgeqsasqmRHVRGAdIAMIF 110
Cdd:cd03228   17 VLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDL-------------ESLRKN-IAYVP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMtslnpVF--TVGEQIaesirlhqgasheeamveakrmldqvripeakailsryphqLSGGMRQRVMIAMALSCRPA 188
Cdd:cd03228   83 QDPF-----LFsgTIRENI-----------------------------------------LSGGQRQRIAIARALLRDPP 116
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGE 246
Cdd:cd03228  117 ILILDEATSALDPETEALILEALRALAKGKT--VIVIAHRLSTIRD-ADRIIVLDDGR 171
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
28-289 3.53e-25

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 107.09  E-value: 3.53e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  28 RVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGEQSASQMrHVRGADIA 107
Cdd:PRK10851  14 RTQVLNDISLDIPSGQMVALLGPSGSGKT----TLLRII--AG---------LEHQTSGHIRFHGTDVSRL-HARDRKVG 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEpmTSLNPVFTVGEQIAESIRL---HQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSGGMRQRVMIAMALS 184
Cdd:PRK10851  78 FVFQH--YALFRHMTVFDNIAFGLTVlprRERPNAAAIKAKVTQLLEMVQLAH---LADRYPAQLSGGQKQRVALARALA 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 185 CRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPY 264
Cdd:PRK10851 153 VEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRF 232
                        250       260
                 ....*....|....*....|....*....
gi 949724212 265 TKALLAAVPQL-GAMNGHEL---PRRFPL 289
Cdd:PRK10851 233 VLEFMGEVNRLqGTIRGGQFhvgAHRWPL 261
cbiO PRK13641
energy-coupling factor transporter ATPase;
336-556 3.54e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 105.68  E-value: 3.54e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASK-LQPLRRDIQFIFQDPYASL 414
Cdd:PRK13641  19 EKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKnLKKLRKKVSLVFQFPEAQL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DpRQTVGYSILEPLRVHGLLQGDAGSKRVAWLlERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK13641  99 F-ENTVLKDVEFGPKNFGFSEDEAKEKALKWL-KKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGL 176
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 495 DVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK13641 177 DPEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE 237
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
339-547 3.70e-25

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 103.73  E-value: 3.70e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAaskLQPLRRDIQFIFQDPY------- 411
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIG---LHDLRSRISIIPQDPVlfsgtir 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 412 ASLDPRQTVG----YSILEplRVHgllqgdagskrvawLLERVGLLPEHAwRYPHE-----FSGGQRQRICIARALALNP 482
Cdd:cd03244   96 SNLDPFGEYSdeelWQALE--RVG--------------LKEFVESLPGGL-DTVVEeggenLSVGQRQLLCLARALLRKS 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 483 KVIIADESVSALDVSIRGQIINLmldLQREL-GIAYLFISHdmavveRI-----SHRVAVMYLGQIVEIGT 547
Cdd:cd03244  159 KILVLDEATASVDPETDALIQKT---IREAFkDCTVLTIAH------RLdtiidSDRILVLDKGRVVEFDS 220
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
339-547 4.19e-25

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 109.87  E-value: 4.19e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPY---ASLd 415
Cdd:COG1132  355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDL---TLESLRRQIGVVPQDTFlfsGTI- 430
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 pRQTVGYSileplrvhgllQGDAGSKRVAWLLERVGLlpehawrypHEF-------------------SGGQRQRICIAR 476
Cdd:COG1132  431 -RENIRYG-----------RPDATDEEVEEAAKAAQA---------HEFiealpdgydtvvgergvnlSGGQRQRIAIAR 489
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 477 ALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHdmavveRIS-----HRVAVMYLGQIVEIGT 547
Cdd:COG1132  490 ALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAH------RLStirnaDRILVLDDGRIVEQGT 557
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
310-597 5.05e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 106.09  E-value: 5.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 310 GEPILRVRNLVTRFPlrsgilNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEI----IFNG 385
Cdd:PRK13631  18 DDIILRVKNLYCVFD------EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 386 QRIDTLAAS---------KLQPLRRDIQFIFQDPYASLDpRQTVGYSIL-EPLRVhGLLQGDAgSKRVAWLLERVGLLPE 455
Cdd:PRK13631  92 DKKNNHELItnpyskkikNFKELRRRVSMVFQFPEYQLF-KDTIEKDIMfGPVAL-GVKKSEA-KKLAKFYLNKMGLDDS 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 456 HAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVA 535
Cdd:PRK13631 169 YLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVI 247
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 536 VMYLGQIVEIGTRRAVFENpQHPYTRKLMAAVPVA----DPSHHRPQRVLLSDDIPSNIRKRGEEI 597
Cdd:PRK13631 248 VMDKGKILKTGTPYEIFTD-QHIINSTSIQVPRVIqvinDLIKKDPKYKKLYQKQPRTIEQLADAI 312
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
310-542 6.97e-25

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 101.74  E-value: 6.97e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 310 GEPILRVRNLVTRfplrsgilnrvtrevHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRID 389
Cdd:cd03215    1 GEPVLEVRGLSVK---------------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVT 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 390 tlAASKLQPLRRDIQFIFQDpyasldpRQTVG----YSILEPLRVHGLLqgdagskrvawllervgllpehawryphefS 465
Cdd:cd03215   66 --RRSPRDAIRAGIAYVPED-------RKREGlvldLSVAENIALSSLL------------------------------S 106
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 466 GGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:cd03215  107 GGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
9-272 1.10e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 104.02  E-value: 1.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEqqrvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRN---- 84
Cdd:PRK14271  18 AAPAMAAVNLTLGFAGK----TVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSifny 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  85 RQVIELGEQsasqmrhvrgadIAMIFQEPmtslNPV-FTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEA-KAIL 162
Cdd:PRK14271  94 RDVLEFRRR------------VGMLFQRP----NPFpMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAvKDRL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 163 SRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIADRVLVM 242
Cdd:PRK14271 158 SDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRLT--VIIVTHNLAQAARISDRAALF 235
                        250       260       270
                 ....*....|....*....|....*....|
gi 949724212 243 YQGEAVETGSVEQIFHAPQHPYTKALLAAV 272
Cdd:PRK14271 236 FDGRLVEEGPTEQLFSSPKHAETARYVAGL 265
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
299-549 1.14e-24

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 108.65  E-value: 1.14e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  299 EPQTEQDTVVEGEPILRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQR 378
Cdd:TIGR02203 316 EKDTGTRAIERARGDVEFRNVTFRYP---------GRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDS 386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  379 GEIIFNGqriDTLAASKLQPLRRDIQFIFQDPYASLDP-RQTVGYSILEplrvhgllqgDAGSKRV------AWLLERVG 451
Cdd:TIGR02203 387 GQILLDG---HDLADYTLASLRRQVALVSQDVVLFNDTiANNIAYGRTE----------QADRAEIeralaaAYAQDFVD 453
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  452 LLP--------EHAWRypheFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHD 523
Cdd:TIGR02203 454 KLPlgldtpigENGVL----LSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQ--GRTTLVIAHR 527
                         250       260
                  ....*....|....*....|....*.
gi 949724212  524 MAVVERiSHRVAVMYLGQIVEIGTRR 549
Cdd:TIGR02203 528 LSTIEK-ADRIVVMDDGRIVERGTHN 552
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
9-266 1.17e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 103.59  E-value: 1.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEqqrvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRrNRQVI 88
Cdd:PRK14246   7 AEDVFNISRLYLYINDK----AILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYF-GKDIF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELgeqSASQMRHvrgaDIAMIFQEPmtSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRI-PEAKAILSRYPH 167
Cdd:PRK14246  82 QI---DAIKLRK----EVGMVFQQP--NPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLwKEVYDRLNSPAS 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIADRVLVMYQGEA 247
Cdd:PRK14246 153 QLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIA--IVIVSHNPQQVARVADYVAFLYNGEL 230
                        250
                 ....*....|....*....
gi 949724212 248 VETGSVEQIFHAPQHPYTK 266
Cdd:PRK14246 231 VEWGSSNEIFTSPKNELTE 249
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
19-248 1.26e-24

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 101.95  E-value: 1.26e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQM 98
Cdd:cd03226    4 NISFSYKKGT-EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLN--------------GKPIKAKE 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHVRgadIAMIFQEPMTSLnpvF--TVGEQIAESIRLhqgASHEEAMVEAkrMLDQVRIPEAKailSRYPHQLSGGMRQR 176
Cdd:cd03226   69 RRKS---IGYVMQDVDYQL---FtdSVREELLLGLKE---LDAGNEQAET--VLKDLDLYALK---ERHPLSLSGGQKQR 134
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAV 248
Cdd:cd03226  135 LAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIREL-AAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
31-252 1.71e-24

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 107.94  E-value: 1.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSL-MHLIEQAGGEVSCDEMLLRRRNRQviELGEQsasqmrhvrgadIAMI 109
Cdd:COG1132  355 VLKDISLTIPPGETVALVGPSGSGKS-TLVNLlLRFYDPTSGRILIDGVDIRDLTLE--SLRRQ------------IGVV 419
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEPMtslnpVF--TvgeqIAESIRL-HQGASHEEaMVEAKRMLdqvripEAKAILSRYPHQ-----------LSGGMRQ 175
Cdd:COG1132  420 PQDTF-----LFsgT----IRENIRYgRPDATDEE-VEEAAKAA------QAHEFIEALPDGydtvvgergvnLSGGQRQ 483
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 176 RVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVETGS 252
Cdd:COG1132  484 RIAIARALLKDPPILILDEATSALDTETEALIQEALERLMKGRT--TIVIAHRLSTIRN-ADRILVLDDGRIVEQGT 557
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
13-251 1.94e-24

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 101.68  E-value: 1.94e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIE-LG 91
Cdd:cd03266    2 ITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARRrLG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASqmrhvrgadiamifqepmTSLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSG 171
Cdd:cd03266   82 FVSDS------------------TGLYDRLTARENLEYFAGLY-GLKGDELTARLEELADRLGM---EELLDRRVGGFST 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03266  140 GMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQL-RALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
19-257 1.99e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 103.29  E-value: 1.99e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTAlSLMHLIEQAggevSCDEMLLrrrNRQVIelgeqSASQM 98
Cdd:PRK13648  12 NVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIA-KLMIGIEKV----KSGEIFY---NNQAI-----TDDNF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHVRgADIAMIFQEPMTSLnpvftVGEQIAESIRL---HQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQ 175
Cdd:PRK13648  79 EKLR-KHIGIVFQNPDNQF-----VGSIVKYDVAFgleNHAVPYDEMHRRVSEALKQVDMLERA---DYEPNALSGGQKQ 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 176 RVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADiADRVLVMYQGEAVETGSVEQ 255
Cdd:PRK13648 150 RVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTE 228

                 ..
gi 949724212 256 IF 257
Cdd:PRK13648 229 IF 230
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
313-552 2.03e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 103.39  E-value: 2.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPlrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtLA 392
Cdd:PRK13636   5 ILKVEELNYNYS----------DGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 ASKLQPLRRDIQFIFQDPyasldPRQTVGYSILEPLRVHGL---LQGDAGSKRVAWLLERVGLlpEHAWRYP-HEFSGGQ 468
Cdd:PRK13636  74 RKGLMKLRESVGMVFQDP-----DNQLFSASVYQDVSFGAVnlkLPEDEVRKRVDNALKRTGI--EHLKDKPtHCLSFGQ 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 469 RQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTR 548
Cdd:PRK13636 147 KKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNP 226

                 ....
gi 949724212 549 RAVF 552
Cdd:PRK13636 227 KEVF 230
cbiO PRK13640
energy-coupling factor transporter ATPase;
14-261 2.08e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 103.34  E-value: 2.08e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  14 AVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTAlslmHLIEqagGEVSCDEMLLRRRNRQVIELGEQ 93
Cdd:PRK13640   5 IVEFKHVSFTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTIS----KLIN---GLLLPDDNPNSKITVDGITLTAK 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 SASQMRHVRGadiaMIFQEPMTSLNPVfTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEakaILSRYPHQLSGGM 173
Cdd:PRK13640  78 TVWDIREKVG----IVFQNPDNQFVGA-TVGDDVAFGLE-NRAVPRPEMIKIVRDVLADVGMLD---YIDSEPANLSGGQ 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 174 RQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGvVADIADRVLVMYQGEAVETGSV 253
Cdd:PRK13640 149 KQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDID-EANMADQVLVLDDGKLLAQGSP 227

                 ....*...
gi 949724212 254 EQIFHAPQ 261
Cdd:PRK13640 228 VEIFSKVE 235
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
335-553 2.47e-24

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 101.92  E-value: 2.47e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 335 REVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPYasL 414
Cdd:cd03254   14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDI---SRKSLRSMIGVVLQDTF--L 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DPRqtvgySILEPLRVHGLlqgDAGSKRVAWLLERVGL------LPEHAWRYPHE----FSGGQRQRICIARALALNPKV 484
Cdd:cd03254   89 FSG-----TIMENIRLGRP---NATDEEVIEAAKEAGAhdfimkLPNGYDTVLGEnggnLSQGERQLLAIARAMLRDPKI 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 485 IIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:cd03254  161 LILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEGTHDELLA 226
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
341-523 3.35e-24

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 100.63  E-value: 3.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTtgraLLR----LVESQRGEIIFNGQRIDTLAASklqpLRRDIQFIFqdPYASLDP 416
Cdd:COG4133   19 SGLSFTLAAGEALALTGPNGSGKTT----LLRilagLLPPSAGEVLWNGEPIRDARED----YRRRLAYLG--HADGLKP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVgysiLEPLRVHGLLQGDAGSKRVAW-LLERVGLLPeHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:COG4133   89 ELTV----RENLRFWAALYGLRADREAIDeALEAVGLAG-LADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALD 163
                        170       180
                 ....*....|....*....|....*...
gi 949724212 496 VSIRGQIINLMLDLQRELGIAyLFISHD 523
Cdd:COG4133  164 AAGVALLAELIAAHLARGGAV-LLTTHQ 190
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
342-547 4.08e-24

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 101.15  E-value: 4.08e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPYASLDprqTVG 421
Cdd:cd03253   19 DVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREV---TLDSLRRAIGVVPQDTVLFND---TIG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 422 YSIL---------------EPLRVHGLLQG--DAGSKRVAwllERvGLlpehawryphEFSGGQRQRICIARALALNPKV 484
Cdd:cd03253   93 YNIRygrpdatdeevieaaKAAQIHDKIMRfpDGYDTIVG---ER-GL----------KLSGGEKQRVAIARAILKNPPI 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 485 IIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGT 547
Cdd:cd03253  159 LLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGT 218
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
9-228 4.88e-24

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 101.01  E-value: 4.88e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRqvi 88
Cdd:PRK10584   3 AENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDE--- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 elgEQSASqmrhVRGADIAMIFQEPMtsLNPVFTVGEQIaESIRLHQGASHEEAMVEAKRMLDQVRIPEAkaiLSRYPHQ 168
Cdd:PRK10584  80 ---EARAK----LRAKHVGFVFQSFM--LIPTLNALENV-ELPALLRGESSRQSRNGAKALLEQLGLGKR---LDHLPAQ 146
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHD 228
Cdd:PRK10584 147 LSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHD 206
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
313-551 5.13e-24

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 102.49  E-value: 5.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtla 392
Cdd:COG4152    1 MLELKGLTKRF-----------GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD--- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 393 asklqplrrdiqfifqdpyasLDPRQTVGY-----------SILEPL----RVHGLLQGDAgSKRVAWLLERVGlLPEHA 457
Cdd:COG4152   67 ---------------------PEDRRRIGYlpeerglypkmKVGEQLvylaRLKGLSKAEA-KRRADEWLERLG-LGDRA 123
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 458 WRYPHEFSGGQRQRICIARALALNPKVIIADESVSALD-VSirgqiINLMLDLQREL---GIAYLFISHDMAVVERISHR 533
Cdd:COG4152  124 NKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDpVN-----VELLKDVIRELaakGTTVIFSSHQMELVEELCDR 198
                        250
                 ....*....|....*...
gi 949724212 534 VAVMYLGQIVEIGTRRAV 551
Cdd:COG4152  199 IVIINKGRKVLSGSVDEI 216
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
33-544 5.82e-24

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 105.92  E-value: 5.82e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI----EQAGGEVSCDemllrrrnrqvielgeqsasqmrhvRGADIAM 108
Cdd:COG0488   15 DDVSLSINPGDRIGLVGRNGAGKS----TLLKILagelEPDSGEVSIP-------------------------KGLRIGY 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPmtSLNPVFTVGEQIAESIR------------LHQGASHEEAMVE-------------------AKRMLDQVRIPE 157
Cdd:COG0488   66 LPQEP--PLDDDLTVLDTVLDGDAelraleaeleelEAKLAEPDEDLERlaelqeefealggweaearAEEILSGLGFPE 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 158 AkaILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDV-TIQ--AQILqlikvlqQDMSMGVIFITHD------ 228
Cdd:COG0488  144 E--DLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLeSIEwlEEFL-------KNYPGTVLVVSHDryfldr 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 229 -MGVVADIADRVLVMYQG------------EAVETGSVEQI-------------FHAPQHPYTKAlLAAVPQLGAMNGHE 282
Cdd:COG0488  215 vATRILELDRGKLTLYPGnysayleqraerLEQEAAAYAKQqkkiakeeefirrFRAKARKAKQA-QSRIKALEKLEREE 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 283 LPRR--FPLISLHDPSHVepqteqdtvveGEPILRVRNLVTRFPlrsgilnrvTREVhaVENVSFDLWPGETLSLVGESG 360
Cdd:COG0488  294 PPRRdkTVEIRFPPPERL-----------GKKVLELEGLSKSYG---------DKTL--LDDLSLRIDRGDRIGLIGPNG 351
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 361 CGKSTTGRALLRLVESQRGEIIFnGQRIdtlaasklqplrrDIQFIFQDpYASLDPRQTVgysiLEPLRvhgLLQGDAGS 440
Cdd:COG0488  352 AGKSTLLKLLAGELEPDSGTVKL-GETV-------------KIGYFDQH-QEELDPDKTV----LDELR---DGAPGGTE 409
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 441 KRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQrelGiAYLFI 520
Cdd:COG0488  410 QEVRGYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETLEALEEALDDFP---G-TVLLV 485
                        570       580
                 ....*....|....*....|....
gi 949724212 521 SHDMAVVERISHRVAVMYLGQIVE 544
Cdd:COG0488  486 SHDRYFLDRVATRILEFEDGGVRE 509
cbiO PRK13641
energy-coupling factor transporter ATPase;
34-257 6.97e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 102.21  E-value: 6.97e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLrrrnrqVIELGEQSASQMRHvrgaDIAMIFQEP 113
Cdd:PRK13641  25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHI------TPETGNKNLKKLRK----KVSLVFQFP 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 114 MTSLnpvF--TVGEQIaESIRLHQGASHEEAMVEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:PRK13641  95 EAQL---FenTVLKDV-EFGPKNFGFSEDEAKEKALKWLKKVGLSED--LISKSPFELSGGQMRRVAIAGVMAYEPEILC 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13641 169 LDEPAAGLDPEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIF 233
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
339-547 7.68e-24

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 100.64  E-value: 7.68e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqplrrdiqfifqdpyasldpRQ 418
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWL--------------------RR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSILEPLRVHGLLQGDAGSKRVAWLLERVgllpEHAWRYP--HEF-------------------SGGQRQRICIARA 477
Cdd:cd03252   77 QVGVVLQENVLFNRSIRDNIALADPGMSMERV----IEAAKLAgaHDFiselpegydtivgeqgaglSGGQRQRIAIARA 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 478 LALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGT 547
Cdd:cd03252  153 LIHNPRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGS 219
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
33-240 9.52e-24

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 99.23  E-value: 9.52e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   33 RNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDEMLlrrrnrqVIELGEQSASQMRHvrgADIAMIFQ 111
Cdd:TIGR03608  15 DDLNLTIEKGKMYAIIGESGSGKS-TLLNIIGLLEKfDSGQVYLNGQE-------TPPLNSKKASKFRR---EKLGYLFQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  112 epmtslNPVFTVGEQIAESIRL---HQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:TIGR03608  84 ------NFALIENETVEENLDLglkYKKLSKKEKREKKKEALEKVGL---NLKLKQKIYELSGGEQQRVALARAILKPPP 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 949724212  189 VLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMgVVADIADRVL 240
Cdd:TIGR03608 155 LILADEPTGSLDPKNRDEVLDLLLEL-NDEGKTIIIVTHDP-EVAKQADRVI 204
cbiO PRK13645
energy-coupling factor transporter ATPase;
31-257 1.03e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 101.62  E-value: 1.03e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH--LIEQAGGEVSCDemllrrrnrQVIELGEQSASQMRHVRgADIAM 108
Cdd:PRK13645  26 ALNNTSLTFKKNKVTCVIGTTGSGKS-TMIQLTNglIISETGQTIVGD---------YAIPANLKKIKEVKRLR-KEIGL 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPMTSLnpvftVGEQIAESIR---LHQGASHEEAMVEAKRMLDQVRIPEAKAilSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:PRK13645  95 VFQFPEYQL-----FQETIEKDIAfgpVNLGENKQEAYKKVPELLKLVQLPEDYV--KRSPFELSGGQKRRVALAGIIAM 167
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 186 RPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13645 168 DGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
33-228 1.33e-23

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 99.09  E-value: 1.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSvTAL-SLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRgADIAMIFQ 111
Cdd:COG4133   19 SGLSFTLAAGEALALTGPNGSGKT-TLLrILAGLLPPSAGEVLWN--------------GEPIRDAREDYR-RRLAYLGH 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EPMtsLNPVFTVGEQIAESIRLHQGASHEEAMVEAkrmLDQVRIPEAkaiLSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:COG4133   83 ADG--LKPELTVRENLRFWAALYGLRADREAIDEA---LEAVGLAGL---ADLPVRQLSAGQKRRVALARLLLSPAPLWL 154
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHD 228
Cdd:COG4133  155 LDEPFTALDAAGVALLAELIAAHLARGGA-VLLTTHQ 190
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
340-557 1.45e-23

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 99.46  E-value: 1.45e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqplrrdiqFIFQDpyASLDPRQT 419
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRM--------VVFQN--YSLLPWLT 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  420 VGYSIlePLRVHGLLQGDAGSKRVAWLLERVGL--LPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:TIGR01184  71 VRENI--ALAVDRVLPDLSKSERRAIVEEHIALvgLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDAL 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212  498 IRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVM------YLGQIVEIG-----TRRAVFENPQH 557
Cdd:TIGR01184 149 TRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLtngpaaNIGQILEVPfprprDRLEVVEDPSY 219
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
339-561 2.22e-23

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 99.86  E-value: 2.22e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLR---LVESQR--GEIIFNGQridTLAASKLQP--LRRDIQFIFQDPY 411
Cdd:PRK14243  25 AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRlndLIPGFRveGKVTFHGK---NLYAPDVDPveVRRRIGMVFQKPN 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 412 ASldPRqtvgySILEPL----RVHGLlQGDAG-----SKRVAWLLERV-------GLlpehawryphEFSGGQRQRICIA 475
Cdd:PRK14243 102 PF--PK-----SIYDNIaygaRINGY-KGDMDelverSLRQAALWDEVkdklkqsGL----------SLSGGQQQRLCIA 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 476 RALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVM---------YLGQIVEIG 546
Cdd:PRK14243 164 RAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTI--IIVTHNMQQAARVSDMTAFFnveltegggRYGYLVEFD 241
                        250
                 ....*....|....*
gi 949724212 547 TRRAVFENPQHPYTR 561
Cdd:PRK14243 242 RTEKIFNSPQQQATR 256
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
29-246 2.92e-23

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 98.09  E-value: 2.92e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   29 VSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQAG-GEVSCD-EMLLRRRNRQVielgeqsASQMRHvrgadI 106
Cdd:TIGR02673  15 VAALHDVSLHIRKGEFLFLTGPSGAGKT-TLLKLLYGALTPSrGQVRIAgEDVNRLRGRQL-------PLLRRR-----I 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  107 AMIFQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPE-AKAilsrYPHQLSGGMRQRVMIAMALSC 185
Cdd:TIGR02673  82 GVVFQD--FRLLPDRTVYENVALPLEV-RGKKEREIQRRVGAALRQVGLEHkADA----FPEQLSGGEQQRVAIARAIVN 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212  186 RPAVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:TIGR02673 155 SPPLLLADEPTGNLDPDLSERILDLLKRLNK-RGTTVIVATHDLSLVDRVAHRVIILDDGR 214
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
32-262 2.94e-23

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 98.69  E-value: 2.94e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   32 VRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ--AGGevscdemlLRRRNRQVIElgeqsasqmrhvRGADIAMI 109
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKS-TLLNLISGLAQptSGG--------VILEGKQITE------------PGPDRMVV 59
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  110 FQEpmTSLNPVFTVGEQIA---ESIRLHQGASHEEAMVEakRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCR 186
Cdd:TIGR01184  60 FQN--YSLLPWLTVRENIAlavDRVLPDLSKSERRAIVE--EHIALVGLTEAA---DKRPGQLSGGMKQRVAIARALSIR 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  187 PAVLIADEPTTALDV----TIQAQILQLIkvlqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI-FHAPQ 261
Cdd:TIGR01184 133 PKVLLLDEPFGALDAltrgNLQEELMQIW----EEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPR 208

                  .
gi 949724212  262 H 262
Cdd:TIGR01184 209 D 209
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
350-546 2.98e-23

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 98.33  E-value: 2.98e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 350 GETLSLVGESGCGKSTtgraLLRLVE----SQRGEIIFNGQRIDTLaasklQPLRRDIQFIFQDP--YASLDPRQTVGYS 423
Cdd:cd03298   24 GEITAIVGPSGSGKST----LLNLIAgfetPQSGRVLINGVDVTAA-----PPADRPVSMLFQENnlFAHLTVEQNVGLG 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 424 ILEPLRVHGLLQgdagsKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQII 503
Cdd:cd03298   95 LSPGLKLTAEDR-----QAIEVALARVGL-AGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEML 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 949724212 504 NLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03298  169 DLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
342-556 5.73e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 99.32  E-value: 5.73e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDlwPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFnGQRidTLAASK----LQPLRRDIQFIFQDPYASLDpR 417
Cdd:PRK13634  27 NVSIP--SGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GER--VITAGKknkkLKPLRKKVGIVFQFPEHQLF-E 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSI-LEPLRVhGLLQGDAgSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:PRK13634 101 ETVEKDIcFGPMNF-GVSEEDA-KQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDP 178
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 497 SIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK13634 179 KGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPD 238
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
34-260 6.02e-23

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 100.56  E-value: 6.02e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDemllrrrnrqvielGE---QSASQMRhvrgaDIAMI 109
Cdd:PRK11432  24 NLNLTIKQGTMVTLLGPSGCGKT-TVLRLVAGLEKpTEGQIFID--------------GEdvtHRSIQQR-----DICMV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAmveakrmldQVRIPEAKAIL------SRYPHQLSGGMRQRVMIAMAL 183
Cdd:PRK11432  84 FQS--YALFPHMSLGENVGYGLKM-LGVPKEER---------KQRVKEALELVdlagfeDRYVDQISGGQQQRVALARAL 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK11432 152 ILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQP 228
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
311-555 7.08e-23

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 98.14  E-value: 7.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFplrSGILnrvtrevhAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDT 390
Cdd:PRK11300   3 QPLLSVSGLMMRF---GGLL--------AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LAASKLQplRRDIQFIFQDpyASLDPRQTVgysiLEPLRV-----------HGLLQGDA-------GSKRVAWLLERVGL 452
Cdd:PRK11300  72 LPGHQIA--RMGVVRTFQH--VRLFREMTV----IENLLVaqhqqlktglfSGLLKTPAfrraeseALDRAATWLERVGL 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 453 LpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISH 532
Cdd:PRK11300 144 L-EHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISD 222
                        250       260
                 ....*....|....*....|...
gi 949724212 533 RVAVMYLGQIVEIGTRRAVFENP 555
Cdd:PRK11300 223 RIYVVNQGTPLANGTPEEIRNNP 245
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
12-265 9.43e-23

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 97.92  E-value: 9.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQAG---------GEVSCDEMLLRR 82
Cdd:PRK14239   5 ILQVSDLSVYYNKKK----ALNSVSLDFYPNEITALIGPSGSGKS----TLLRSINRMNdlnpevtitGSIVYNGHNIYS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  83 RNRQVIELGEQsasqmrhvrgadIAMIFQEPmtslNPV-FTVGEQIAESIRLhQGASHEEAMVEA-KRMLDQVRI-PEAK 159
Cdd:PRK14239  77 PRTDTVDLRKE------------IGMVFQQP----NPFpMSIYENVVYGLRL-KGIKDKQVLDEAvEKSLKGASIwDEVK 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 160 AILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgvIFITHDMGVVADIADRV 239
Cdd:PRK14239 140 DRLHDSALGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTM--LLVTRSMQQASRISDRT 217
                        250       260
                 ....*....|....*....|....*.
gi 949724212 240 LVMYQGEAVETGSVEQIFHAPQHPYT 265
Cdd:PRK14239 218 GFFLDGDLIEYNDTKQMFMNPKHKET 243
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
339-547 9.88e-23

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 97.30  E-value: 9.88e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPYASLDP-R 417
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDY---TLASLRRQIGLVSQDVFLFNDTvA 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILeplrvhgllqgDAGSKRVawllervgllpEHAWR--YPHEF-------------------SGGQRQRICIAR 476
Cdd:cd03251   94 ENIAYGRP-----------GATREEV-----------EEAARaaNAHEFimelpegydtvigergvklSGGQRQRIAIAR 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 477 ALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGT 547
Cdd:cd03251  152 ALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTIEN-ADRIVVLEDGKIVERGT 219
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
19-257 1.06e-22

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 96.91  E-value: 1.06e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRqvIELGEQsasqm 98
Cdd:cd03254    7 NVNFSYDEKK-PVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISR--KSLRSM----- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 rhvrgadIAMIFQEPmtslnpvFTVGEQIAESIRL-HQGASHEEAMVEAK--RMLDQV-RIPEA-KAILSRYPHQLSGGM 173
Cdd:cd03254   79 -------IGVVLQDT-------FLFSGTIMENIRLgRPNATDEEVIEAAKeaGAHDFImKLPNGyDTVLGENGGNLSQGE 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 174 RQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVETGSV 253
Cdd:cd03254  145 RQLLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRT--SIIIAHRLSTIKN-ADKILVLDDGKIIEEGTH 221

                 ....
gi 949724212 254 EQIF 257
Cdd:cd03254  222 DELL 225
cbiO PRK13645
energy-coupling factor transporter ATPase;
336-554 1.27e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 98.54  E-value: 1.27e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRI--DTLAASKLQPLRRDIQFIFQDPYAS 413
Cdd:PRK13645  23 EFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpaNLKKIKEVKRLRKEIGLVFQFPEYQ 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDpRQTVGYSI-LEPlrVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVS 492
Cdd:PRK13645 103 LF-QETIEKDIaFGP--VNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTG 179
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 493 ALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFEN 554
Cdd:PRK13645 180 GLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN 241
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
31-260 2.23e-22

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 99.25  E-value: 2.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDemllrrrNRQVIELgeqSASQmRHVRgadiaMI 109
Cdd:PRK09452  29 VISNLDLTINNGEFLTLLGPSGCGKT-TVLRLIAGFETPdSGRIMLD-------GQDITHV---PAEN-RHVN-----TV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAmveAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAV 189
Cdd:PRK09452  92 FQS--YALFPHMTVFENVAFGLRM-QKTPAAEI---TPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKV 165
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 190 LIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK09452 166 LLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEP 236
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
12-246 2.35e-22

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 94.81  E-value: 2.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAfeqeqqrvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCD-EMLLRRRNRQVIEL 90
Cdd:cd03215    4 VLEVRGLSVK--------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDgKPVTRRSPRDAIRA 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 GEQSASQMRHVRGadiamifqepmtsLNPVFTVGEQIAesirlhqgasheeamveakrmldqvripeakailsrYPHQLS 170
Cdd:cd03215   76 GIAYVPEDRKREG-------------LVLDLSVAENIA------------------------------------LSSLLS 106
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 171 GGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03215  107 GGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGR 181
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
29-246 3.06e-22

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 95.17  E-value: 3.06e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDEMLLRRRNRQVIELGEQSasqmrhvrgadIA 107
Cdd:cd03292   14 TAALDGINISISAGEFVFLVGPSGAGKS-TLLKLIYKEELpTSGTIRVNGQDVSDLRGRAIPYLRRK-----------IG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:cd03292   82 VVFQD--FRLLPDRNVYENVAFALEV-TGVPPREIRKRVPAALELVGLSHKH---RALPAELSGGEQQRVAIARAIVNSP 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 188 AVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03292  156 TILIADEPTGNLDPDTTWEIMNLLKKINK-AGTTVVVATHAKELVDTTRHRVIALERGK 213
cbiO PRK13646
energy-coupling factor transporter ATPase;
336-568 3.45e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 97.16  E-value: 3.45e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASK-LQPLRRDIQFIFQDPYASL 414
Cdd:PRK13646  19 EHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKyIRPVRKRIGMVFQFPESQL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DpRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLErVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK13646  99 F-EDTVEREIIFGPKNFKMNLDEVKNYAHRLLMD-LGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGL 176
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 495 DVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFEnpQHPYTRKLMAAVP 568
Cdd:PRK13646 177 DPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFK--DKKKLADWHIGLP 248
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
13-256 3.64e-22

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 95.19  E-value: 3.64e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCD-EMLLRRRNRQVIELG 91
Cdd:cd03224    1 LEVENLNAGYGKSQ----ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDgRDITGLPPHERARAG 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 eqsasqmrhvrgadIAMIFQEPMtsLNPVFTVgeqiAESIRLhqgASHEEAMVEAKRMLDQV--RIPEAKAILSRYPHQL 169
Cdd:cd03224   77 --------------IGYVPEGRR--IFPELTV----EENLLL---GAYARRRAKRKARLERVyeLFPRLKERRKQLAGTL 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVE 249
Cdd:cd03224  134 SGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIREL-RDEGVTILLVEQNARFALEIADRAYVLERGRVVL 212

                 ....*..
gi 949724212 250 TGSVEQI 256
Cdd:cd03224  213 EGTAAEL 219
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
18-266 3.99e-22

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 96.06  E-value: 3.99e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  18 LNIAFEQEQQRV-----SAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIE-----QAGGEVSCDEMLLRRRNRQV 87
Cdd:PRK14267   1 MKFAIETVNLRVyygsnHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElneeaRVEGEVRLFGRNIYSPDVDP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  88 IELGEQsasqmrhvrgadIAMIFQEPmtslNPV--FTVGEQIAESIRLHQgasheeaMVEAKRMLDQV---------RIP 156
Cdd:PRK14267  81 IEVRRE------------VGMVFQYP----NPFphLTIYDNVAIGVKLNG-------LVKSKKELDERvewalkkaaLWD 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 157 EAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIA 236
Cdd:PRK14267 138 EVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYT--IVLVTHSPAQAARVS 215
                        250       260       270
                 ....*....|....*....|....*....|
gi 949724212 237 DRVLVMYQGEAVETGSVEQIFHAPQHPYTK 266
Cdd:PRK14267 216 DYVAFLYLGKLIEVGPTRKVFENPEHELTE 245
cbiO PRK13640
energy-coupling factor transporter ATPase;
336-556 4.58e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 96.41  E-value: 4.58e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGR---ALLRLVESQRGEIIFNGQridTLAASKLQPLRRDIQFIFQDPya 412
Cdd:PRK13640  19 KKPALNDISFSIPRGSWTALIGHNGSGKSTISKlinGLLLPDDNPNSKITVDGI---TLTAKTVWDIREKVGIVFQNP-- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 sldPRQTVGYSILEPLrVHGL----LQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIAD 488
Cdd:PRK13640  94 ---DNQFVGATVGDDV-AFGLenraVPRPEMIKIVRDVLADVGML-DYIDSEPANLSGGQKQRVAIAGILAVEPKIIILD 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 489 ESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVErISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK13640 169 ESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKLLAQGSPVEIFSKVE 235
GguA NF040905
sugar ABC transporter ATP-binding protein;
29-543 6.01e-22

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 99.48  E-value: 6.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHL---IEQAG---GEVSCDEMLLRRRNrqvIELGEQsasqmrhvR 102
Cdd:NF040905  14 VKALDDVNLSVREGEIHALCGENGAGKS----TLMKVlsgVYPHGsyeGEILFDGEVCRFKD---IRDSEA--------L 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 103 GadIAMIFQE----PMTSlnpvftvgeqIAESIRL-HQGASH-----EEAMVEAKRMLDQVRIPEAKAILSRyphQLSGG 172
Cdd:NF040905  79 G--IVIIHQElaliPYLS----------IAENIFLgNERAKRgvidwNETNRRARELLAKVGLDESPDTLVT---DIGVG 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVL-QQDMSmgVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:NF040905 144 KQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELkAQGIT--SIIISHKLNEIRRVADSITVLRDGRTIETL 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 252 SVEQifhapqhpytkallAAVPQ---LGAMNGHELPRRFPlisLHDPShvepqteqdtvvEGEPILRVRNLVTRFPLRSG 328
Cdd:NF040905 222 DCRA--------------DEVTEdriIRGMVGRDLEDRYP---ERTPK------------IGEVVFEVKNWTVYHPLHPE 272
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 329 ilnrvtREVhaVENVSFDLWPGETLSLVGESGCGK-----STTGRALLRLVesqRGEIIFNGQRIDTLAASKlqPLRRDI 403
Cdd:NF040905 273 ------RKV--VDDVSLNVRRGEIVGIAGLMGAGRtelamSVFGRSYGRNI---SGTVFKDGKEVDVSTVSD--AIDAGL 339
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 404 QfifqdpYASLDpRQTVGYSILEPLRVHGLLqgdAGSKRVAwlleRVGLLPEH-----AWRYPHEF-------------- 464
Cdd:NF040905 340 A------YVTED-RKGYGLNLIDDIKRNITL---ANLGKVS----RRGVIDENeeikvAEEYRKKMniktpsvfqkvgnl 405
                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 465 SGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGRIT 483
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
312-536 7.90e-22

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 99.28  E-value: 7.90e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  312 PILRVRNLVTRFPLRSgilnrvtrevHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridTL 391
Cdd:TIGR02857 320 SSLEFSGVSVAYPGRR----------PALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGV---PL 386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  392 AASKLQPLRRDIQFIFQDPYasldprqTVGYSILEPLRvhgLLQGDAGSKRVAWLLERVGL------LPEH----AWRYP 461
Cdd:TIGR02857 387 ADADADSWRDQIAWVPQHPF-------LFAGTIAENIR---LARPDASDAEIREALERAGLdefvaaLPQGldtpIGEGG 456
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212  462 HEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMAVVERISHRVAV 536
Cdd:TIGR02857 457 AGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALADRIVVL 529
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
12-245 8.55e-22

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 94.50  E-value: 8.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGG--EVSCDEMLLRRRNrqvie 89
Cdd:PRK11629   5 LLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKS----TLLHLL---GGldTPTSGDVIFNGQP----- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGEQSASQMRHVRGADIAMIFQepMTSLNPVFTVGEQIAESIrLHQGASHEEAMVEAKRMLDQVRIpEAKAilSRYPHQL 169
Cdd:PRK11629  73 MSKLSSAAKAELRNQKLGFIYQ--FHHLLPDFTALENVAMPL-LIGKKKPAEINSRALEMLAAVGL-EHRA--NHRPSEL 146
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGvVADIADRVLVMYQG 245
Cdd:PRK11629 147 SGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQ-LAKRMSRQLEMRDG 221
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
32-272 8.95e-22

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 95.18  E-value: 8.95e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSvtalSLMHL----IEQAGGEVSCDEMllrrrnrqviELGEQSASQMRHVRgadiA 107
Cdd:COG4559   17 LDDVSLTLRPGELTAIIGPNGAGKS----TLLKLltgeLTPSSGEVRLNGR----------PLAAWSPWELARRR----A 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEpmTSLNPVFTVgeqiAESIRL-----HQGASHEEAMVEakRMLDQVripEAKAILSRYPHQLSGGMRQRVMIAMA 182
Cdd:COG4559   79 VLPQH--SSLAFPFTV----EEVVALgraphGSSAAQDRQIVR--EALALV---GLAHLAGRSYQTLSGGEQQRVQLARV 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 183 L-------SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMsMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQ 255
Cdd:COG4559  148 LaqlwepvDGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRG-GGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEE 226
                        250
                 ....*....|....*..
gi 949724212 256 IFhapqhpyTKALLAAV 272
Cdd:COG4559  227 VL-------TDELLERV 236
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
339-547 1.02e-21

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 99.27  E-value: 1.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDpyASLDPRq 418
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTV---TRASLRRNIAVVFQD--AGLFNR- 423
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 tvgySILEPLRVHgllQGDAGSKRVAWLLERVGLLpEHAWRYPHEF-----------SGGQRQRICIARALALNPKVIIA 487
Cdd:PRK13657 424 ----SIEDNIRVG---RPDATDEEMRAAAERAQAH-DFIERKPDGYdtvvgergrqlSGGERQRLAIARALLKDPPILIL 495
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 488 DESVSALDVSIRGQiINLMLDLQRElGIAYLFISHDMAVVeRISHRVAVMYLGQIVEIGT 547
Cdd:PRK13657 496 DEATSALDVETEAK-VKAALDELMK-GRTTFIIAHRLSTV-RNADRILVFDNGRVVESGS 552
cbiO PRK13643
energy-coupling factor transporter ATPase;
31-328 1.11e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 95.57  E-value: 1.11e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQvielgeqsaSQMRHVRgADIAMIF 110
Cdd:PRK13643  21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQ---------KEIKPVR-KKVGVVF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMTSLNPVfTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIpeAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:PRK13643  91 QFPESQLFEE-TVLKDVAFGPQ-NFGIPKEKAEKIAAEKLEMVGL--ADEFWEKSPFELSGGQMRRVAIAGILAMEPEVL 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHapqhpytkalla 270
Cdd:PRK13643 167 VLDEPTAGLDPKARIEMMQLFESIHQ-SGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ------------ 233
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 271 avpQLGAMNGHELprrfpliSLHDPSHVEPQTEQDTVVEGE--PILRVR--NLVTRFPLRSG 328
Cdd:PRK13643 234 ---EVDFLKAHEL-------GVPKATHFADQLQKTGAVTFEklPITRAElvTLLTSLSVNSG 285
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
9-313 1.40e-21

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 96.83  E-value: 1.40e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   9 ASDVLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ-AGGEVSCDemllrrrnrqv 87
Cdd:PRK11607  16 LTPLLEIRNLTKSFDGQH----AVDDVSLTIYKGEIFALLGASGCGKS-TLLRMLAGFEQpTAGQIMLD----------- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  88 ielGEQSASQMRHVRgaDIAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASHE-EAMVEakRMLDQVRIPE-AKailsRY 165
Cdd:PRK11607  80 ---GVDLSHVPPYQR--PINMMFQS--YALFPHMTVEQNIAFGLKQDKLPKAEiASRVN--EMLGLVHMQEfAK----RK 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 166 PHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQI-LQLIKVLQQdmsMGV--IFITHDMGVVADIADRVLVM 242
Cdd:PRK11607 147 PHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMqLEVVDILER---VGVtcVMVTHDQEEAMTMAGRIAIM 223
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 243 YQGEAVETGSVEQIFHAPQHPYTKALLAAVpqlGAMNGHELPRRFPLISLHDPSHVEP-QTEQD-TVVEGEPI 313
Cdd:PRK11607 224 NRGKFVQIGEPEEIYEHPTTRYSAEFIGSV---NVFEGVLKERQEDGLVIDSPGLVHPlKVDADaSVVDNVPV 293
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
340-523 1.63e-21

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 93.63  E-value: 1.63e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPYASLDprqT 419
Cdd:PRK10247  23 LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTL---KPEIYRQQVSYCAQTPTLFGD---T 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYSILEPLRVHGlLQGDagSKRVAWLLERVGlLPEHAWRYP-HEFSGGQRQRICIARALALNPKVIIADESVSALDVSI 498
Cdd:PRK10247  97 VYDNLIFPWQIRN-QQPD--PAIFLDDLERFA-LPDTILTKNiAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESN 172
                        170       180
                 ....*....|....*....|....*
gi 949724212 499 RGQIINLMLDLQRELGIAYLFISHD 523
Cdd:PRK10247 173 KHNVNEIIHRYVREQNIAVLWVTHD 197
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
341-557 1.86e-21

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 94.45  E-value: 1.86e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTtgraLLRLVESQ----RGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDpyASLDP 416
Cdd:PRK11831  24 DNISLTVPRGKITAIMGPSGIGKTT----LLRLIGGQiapdHGEILFDGENIPAMSRSRLYTVRKRMSMLFQS--GALFT 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLLPEhAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:PRK11831  98 DMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGA-AKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDP 176
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 497 SIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQH 557
Cdd:PRK11831 177 ITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDP 237
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
311-550 1.87e-21

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 98.08  E-value: 1.87e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLVE------SQRGEIIFN 384
Cdd:PRK13549   3 EYLLEMKNITKTFG-----------GVKALDNVSLKVRAGEIVSLCGENGAGKST----LMKVLSgvyphgTYEGEIIFE 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 385 GQridTLAASKLQPL-RRDIQFIFQDpyASLDPRQTVGYSIL---EPLRvHGLLQGDAGSKRVAWLLERVGLLPEHAWRY 460
Cdd:PRK13549  68 GE---ELQASNIRDTeRAGIAIIHQE--LALVKELSVLENIFlgnEITP-GGIMDYDAMYLRAQKLLAQLKLDINPATPV 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 461 pHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLG 540
Cdd:PRK13549 142 -GNLGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDG 219
                        250
                 ....*....|
gi 949724212 541 QivEIGTRRA 550
Cdd:PRK13549 220 R--HIGTRPA 227
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
28-251 1.87e-21

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 92.73  E-value: 1.87e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  28 RVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrNRQVIELGEQSASQMRHVRGadia 107
Cdd:cd03269   12 RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFD-------GKPLDIAARNRIGYLPEERG---- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 mifqepmtsLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:cd03269   81 ---------LYPKMKVIDQLVYLAQLK-GLKKEEARRRIDEWLERLELSEYA---NKRVEELSKGNQQKVQFIAAVIHDP 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 188 AVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03269  148 ELLILDEPFSGLDPVNVELLKDVIREL-ARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
31-257 2.01e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 94.91  E-value: 2.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrRRNRQVIELGEQSASQMRHvrgaDIAMIF 110
Cdd:PRK13636  21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRI--------LFDGKPIDYSRKGLMKLRE----SVGMVF 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMTSLNPVfTVGEQIAESIrLHQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:PRK13636  89 QDPDNQLFSA-SVYQDVSFGA-VNLKLPEDEVRKRVDNALKRTGIEHLK---DKPTHCLSFGQKKRVAIAGVLVMEPKVL 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13636 164 VLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
35-279 2.15e-21

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 95.95  E-value: 2.15e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   35 LSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDEMLLRRRNRQVIELGEQSAsqmrhvrgadIAMIFQEp 113
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKT-TLIRLIAgLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRR----------IGYVFQE- 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  114 mTSLNPVFTVGEQIAESIRLHQGASHEEAMVEAKRMLDqvripeAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIAD 193
Cdd:TIGR02142  84 -ARLFPHLSVRGNLRYGMKRARPSERRISFERVIELLG------IGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMD 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  194 EPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQHPYtkallAAVP 273
Cdd:TIGR02142 157 EPLAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW-----LARE 231

                  ....*.
gi 949724212  274 QLGAMN 279
Cdd:TIGR02142 232 DQGSLI 237
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
29-250 2.32e-21

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 91.34  E-value: 2.32e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAG------GEVSCDEMLLRRRN-RQVIELGeqsasqmrhv 101
Cdd:cd03216   13 VKALDGVSLSVRRGEVHALLGENGAGKS----TLMKIL--SGlykpdsGEILVDGKEVSFASpRDARRAG---------- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 102 rgadIAMIfqepmtslnpvftvgeqiaesirlhqgasheeamveakrmldqvripeakailsrypHQLSGGMRQRVMIAM 181
Cdd:cd03216   77 ----IAMV---------------------------------------------------------YQLSVGERQMVEIAR 95
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVET 250
Cdd:cd03216   96 ALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
340-567 2.76e-21

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 94.39  E-value: 2.76e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRL---VESQR--GEIIFNGQRIdtLAASKLQPLRRDIQFIFQDPyasl 414
Cdd:PRK14271  37 LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMndkVSGYRysGDVLLGGRSI--FNYRDVLEFRRRVGMLFQRP---- 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DP-RQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGL---LPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:PRK14271 111 NPfPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLwdaVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEP 190
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 491 VSALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAV 567
Cdd:PRK14271 191 TSALDPTTTEKIEEFIRSLADRLTV--IIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYVAGL 265
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
29-260 3.44e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 94.10  E-value: 3.44e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemLLRrrnrqvielGEQ-SASQMRHVRGAdIA 107
Cdd:PRK13652  17 KEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSV-----LIR---------GEPiTKENIREVRKF-VG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEPMtslNPVF--TVGEQIA-ESIRLhqgASHEEAMveAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALS 184
Cdd:PRK13652  82 LVFQNPD---DQIFspTVEQDIAfGPINL---GLDEETV--AHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIA 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 185 CRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK13652 154 MEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
339-524 3.48e-21

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 93.23  E-value: 3.48e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKlqplrrdiQFIFQDpyASLDPRQ 418
Cdd:PRK11248  16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER--------GVVFQN--EGLLPWR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSILEPLRvhglLQGDAGSKRVAW---LLERVGLLPEHAwRYPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:PRK11248  86 NVQDNVAFGLQ----LAGVEKMQRLEIahqMLKKVGLEGAEK-RYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD 160
                        170       180
                 ....*....|....*....|....*....
gi 949724212 496 VSIRGQIINLMLDLQRELGIAYLFISHDM 524
Cdd:PRK11248 161 AFTREQMQTLLLKLWQETGKQVLLITHDI 189
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
31-256 3.78e-21

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 92.93  E-value: 3.78e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQaggevscdeMLLRRRNRQVIELGEQSASQMRHVRgADIAMIF 110
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKS----TLTKLIQR---------FYVPENGRVLVDGHDLALADPAWLR-RQVGVVL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEpmtslNPVFTvgEQIAESIRLHQGASHEEAMVEAKRMLDQ----VRIPEA-KAILSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:cd03252   83 QE-----NVLFN--RSIRDNIALADPGMSMERVIEAAKLAGAhdfiSELPEGyDTIVGEQGAGLSGGQRQRIAIARALIH 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 186 RPAVLIADEPTTALDVTIQAQILQLIkvlqQDMSMG--VIFITHDMGVVADiADRVLVMYQGEAVETGSVEQI 256
Cdd:cd03252  156 NPRILIFDEATSALDYESEHAIMRNM----HDICAGrtVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDEL 223
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
340-542 4.23e-21

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 90.74  E-value: 4.23e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqplrrdiqfifqdpyasldpRQT 419
Cdd:cd03246   18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNEL--------------------GDH 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYsileplrvhgLLQGD---AGSkrvawLLERVgllpehawrypheFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:cd03246   78 VGY----------LPQDDelfSGS-----IAENI-------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDV 129
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 949724212 497 SIRGQIINLMLDLqRELGIAYLFISHDMAVVERIShRVAVMYLGQI 542
Cdd:cd03246  130 EGERALNQAIAAL-KAAGATRIVIAHRPETLASAD-RILVLEDGRV 173
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
306-523 4.58e-21

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 97.05  E-value: 4.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  306 TVVEGEPILRVRNLVTRFPLRSGILNrvtrevhaveNVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNG 385
Cdd:TIGR02868 327 AVGLGKPTLELRDLSAGYPGAPPVLD----------GVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDG 396
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  386 QRIDTLAASKlqpLRRDIQFIFQDPYasldprqTVGYSILEPLRvhgLLQGDAGSKRVAWLLERVGLLpEHAWRYPH--- 462
Cdd:TIGR02868 397 VPVSSLDQDE---VRRRVSVCAQDAH-------LFDTTVRENLR---LARPDATDEELWAALERVGLA-DWLRALPDgld 462
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212  463 --------EFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIayLFISHD 523
Cdd:TIGR02868 463 tvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGRTV--VLITHH 529
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
33-256 7.81e-21

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 97.10  E-value: 7.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   33 RNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIElgeqsasqmRHVrgadiAMIFQE 112
Cdd:TIGR00958 498 KGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLH---------RQV-----ALVGQE 563
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  113 PMtslnpVF--TVGEQIAESIRlhqgaSHEEAMVEAKRMLdqvriPEAKAILSRYPH-----------QLSGGMRQRVMI 179
Cdd:TIGR00958 564 PV-----LFsgSVRENIAYGLT-----DTPDEEIMAAAKA-----ANAHDFIMEFPNgydtevgekgsQLSGGQKQRIAI 628
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  180 AMALSCRPAVLIADEPTTALDVTIQAqilqlikVLQQDMS---MGVIFITHDMGVVADiADRVLVMYQGEAVETGSVEQI 256
Cdd:TIGR00958 629 ARALVRKPRVLILDEATSALDAECEQ-------LLQESRSrasRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQL 700
cbiO PRK13649
energy-coupling factor transporter ATPase;
31-257 7.91e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 92.89  E-value: 7.91e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDEMLLRRRNRQvielgeqsaSQMRHVRgADIAMI 109
Cdd:PRK13649  22 ALFDVNLTIEDGSYTAFIGHTGSGKS-TIMQLLNgLHVPTQGSVRVDDTLITSTSKN---------KDIKQIR-KKVGLV 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEPMTSLnpvF--TVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:PRK13649  91 FQFPESQL---FeeTVLKDVAFGPQ-NFGVSQEEAEALAREKLALVGISES--LFEKNPFELSGGQMRRVAIAGILAMEP 164
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 188 AVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:PRK13649 165 KILVLDEPTAGLDPKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
29-545 8.28e-21

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 95.95  E-value: 8.28e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrrrnrqvIELGEQ-SASQMRHVRGADIA 107
Cdd:PRK10982  11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSI--------------LFQGKEiDFKSSKEALENGIS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIFQEpmtsLNPVF--TVGEQIAESIRLHQG--ASHEEAMVEAKRMLDQVRI---PEAKAIlsryphQLSGGMRQRVMIA 180
Cdd:PRK10982  77 MVHQE----LNLVLqrSVMDNMWLGRYPTKGmfVDQDKMYRDTKAIFDELDIdidPRAKVA------TLSVSQMQMIEIA 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 181 MALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQqDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVE-----Q 255
Cdd:PRK10982 147 KAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLK-ERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAgltmdK 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 256 IfhapqhpytkallaavpqLGAMNGHELPRRFPlislhdpshvepqteQDTVVEGEPILRVRNLVTrfplrsgiLNRVTr 335
Cdd:PRK10982 226 I------------------IAMMVGRSLTQRFP---------------DKENKPGEVILEVRNLTS--------LRQPS- 263
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 evhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAAskLQPLRRDIQFIFQDP----- 410
Cdd:PRK10982 264 ----IRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNA--NEAINHGFALVTEERrstgi 337
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 411 YASLDprqtVGY-SILEPLRVH----GLLQGDAGSKRVAWLLERVGL-LPEHAWRYpHEFSGGQRQRICIARALALNPKV 484
Cdd:PRK10982 338 YAYLD----IGFnSLISNIRNYknkvGLLDNSRMKSDTQWVIDSMRVkTPGHRTQI-GSLSGGNQQKVIIGRWLLTQPEI 412
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 485 IIADESVSALDVSIRGQIINLMLDL-QRELGIayLFISHDMAVVERISHRVAVMYLGQIVEI 545
Cdd:PRK10982 413 LMLDEPTRGIDVGAKFEIYQLIAELaKKDKGI--IIISSEMPELLGITDRILVMSNGLVAGI 472
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
19-255 1.06e-20

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 91.52  E-value: 1.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRrrnrqvielgEQSASQM 98
Cdd:cd03251    5 NVTFRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVR----------DYTLASL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RhvrgADIAMIFQEpmtslnpVFTVGEQIAESIRL-HQGASHEEAMVEAkrmldqvRIPEAKAILSRYPH---------- 167
Cdd:cd03251   75 R----RQIGLVSQD-------VFLFNDTVAENIAYgRPGATREEVEEAA-------RAANAHEFIMELPEgydtvigerg 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 -QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGE 246
Cdd:cd03251  137 vKLSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMKNRT--TFVIAHRLSTIEN-ADRIVVLEDGK 213

                 ....*....
gi 949724212 247 AVETGSVEQ 255
Cdd:cd03251  214 IVERGTHEE 222
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
340-567 1.14e-20

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 92.00  E-value: 1.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQplrRDIQFIFQDPyasLDP--- 416
Cdd:PRK11231  18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLA---RRLALLPQHH---LTPegi 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 --RQTVGYSILEPLRVHGLLqGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK11231  92 tvRELVAYGRSPWLSLWGRL-SAEDNARVNQAMEQTRIN-HLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYL 169
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 495 DVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTrravfenPQHPYTRKLMAAV 567
Cdd:PRK11231 170 DINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGT-------PEEVMTPGLLRTV 234
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
12-293 1.82e-20

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 91.37  E-value: 1.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEqagGEVSCDemllrrrnRQVIELG 91
Cdd:PRK13548   2 MLEARNLSVRLGGRT----LLDDVSLTLRPGEVVAILGPNGAGKS----TLLRALS---GELSPD--------SGEVRLN 62
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADI-AMIFQEpmTSLNPVFTVgEQIAESIRLHQGASHEEAMVEAKRMLDQVripEAKAILSRYPHQLS 170
Cdd:PRK13548  63 GRPLADWSPAELARRrAVLPQH--SSLSFPFTV-EEVVAMGRAPHGLSRAEDDALVAAALAQV---DLAHLAGRDYPQLS 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 171 GGMRQRVMIAMAL------SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQ 244
Cdd:PRK13548 137 GGEQQRVQLARVLaqlwepDGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQ 216
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 949724212 245 GEAVETGSVEQIFhapqhpyTKALLAAVPQLGAMNGHELPRRFPLISLH 293
Cdd:PRK13548 217 GRLVADGTPAEVL-------TPETLRRVYGADVLVQPHPETGAPLVLPR 258
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
41-251 1.96e-20

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 89.86  E-value: 1.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  41 RGETLAIVGESGSGKSvtalSLMHLIeqAGGEVSCDEMLLrrrnrqvieLGEQSasqMRHVRGAD--IAMIFQEpmTSLN 118
Cdd:cd03298   23 QGEITAIVGPSGSGKS----TLLNLI--AGFETPQSGRVL---------INGVD---VTAAPPADrpVSMLFQE--NNLF 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 119 PVFTVGEQI--AESIRLHQGASHEEAMveaKRMLDQVRIPEakaILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPT 196
Cdd:cd03298   83 AHLTVEQNVglGLSPGLKLTAEDRQAI---EVALARVGLAG---LEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPF 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 197 TALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03298  157 AALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
29-252 2.28e-20

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 90.68  E-value: 2.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNrqvielgeqsasqMRHVRgADIAM 108
Cdd:cd03249   16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLN-------------LRWLR-SQIGL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPM---TSlnpvftvgeqIAESIRLHQGASHEEAMVEAKRMldqvriPEAKAILSRYPH-----------QLSGGMR 174
Cdd:cd03249   82 VSQEPVlfdGT----------IAENIRYGKPDATDEEVEEAAKK------ANIHDFIMSLPDgydtlvgergsQLSGGQK 145
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 175 QRVMIAMALSCRPAVLIADEPTTALDvTIQAQILQliKVLQQDM-SMGVIFITHDMGVVADiADRVLVMYQGEAVETGS 252
Cdd:cd03249  146 QRIAIARALLRNPKILLLDEATSALD-AESEKLVQ--EALDRAMkGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGT 220
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
336-543 2.46e-20

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 89.96  E-value: 2.46e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKlqpLRRDIQFIFQDP---YA 412
Cdd:cd03245   16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPAD---LRRNIGYVPQDVtlfYG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 SLDPRQTVGYS------ILEPLRVHGLLQgdagskrvawllervgLLPEHawryPHEF-----------SGGQRQRICIA 475
Cdd:cd03245   93 TLRDNITLGAPladderILRAAELAGVTD----------------FVNKH----PNGLdlqigergrglSGGQRQAVALA 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 476 RALALNPKVIIADESVSALDVSIRGQIINlmlDLQREL-GIAYLFISHDMAVVERIShRVAVMYLGQIV 543
Cdd:cd03245  153 RALLNDPPILLLDEPTSAMDMNSEERLKE---RLRQLLgDKTLIIITHRPSLLDLVD-RIIVMDSGRIV 217
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
36-246 3.12e-20

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 89.54  E-value: 3.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   36 SFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDEMLLRRrnrqvielgeqSASQMRHVrgadiAMIFQEpm 114
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKS-TLLNLIAgFIEPASGSIKVNDQSHTG-----------LAPYQRPV-----SMLFQE-- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  115 TSLNPVFTVGEQIAESIR--LHQGASHEEAMVEAKRmldQVRIPEakaILSRYPHQLSGGMRQRVMIAMALSCRPAVLIA 192
Cdd:TIGR01277  79 NNLFAHLTVRQNIGLGLHpgLKLNAEQQEKVVDAAQ---QVGIAD---YLDRLPEQLSGGQRQRVALARCLVRPNPILLL 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 949724212  193 DEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:TIGR01277 153 DEPFSALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGK 206
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
338-546 3.44e-20

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 89.17  E-value: 3.44e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGeTLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaASKLQPLRRDIQFIFQDPyaSLDPR 417
Cdd:cd03264   14 RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDV----LKQPQKLRRRIGYLPQEF--GVYPN 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVgysiLEPLRVHGLLQGDAGS---KRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:cd03264   87 FTV----REFLDYIAWLKGIPSKevkARVDEVLELVNLG-DRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGL 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 949724212 495 DVSIRGQIINLMldlqRELGIAYLFI--SHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03264  162 DPEERIRFRNLL----SELGEDRIVIlsTHIVEDVESLCNQVAVLNKGKLVFEG 211
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
339-549 4.02e-20

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 94.81  E-value: 4.02e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqplRRDIQFIFQDPYasldprq 418
Cdd:TIGR01193 489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTL---RQFINYLPQEPY------- 558
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  419 TVGYSILEPLrvhgLLQGDAG-SKRVAWLLERVGLLPEHAWRYPHEF-----------SGGQRQRICIARALALNPKVII 486
Cdd:TIGR01193 559 IFSGSILENL----LLGAKENvSQDEIWAACEIAEIKDDIENMPLGYqtelseegssiSGGQKQRIALARALLTDSKVLI 634
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212  487 ADESVSALDVSIRGQIINLMLDLQRELGIaylFISHDMAVVERiSHRVAVMYLGQIVEIGTRR 549
Cdd:TIGR01193 635 LDESTSNLDTITEKKIVNNLLNLQDKTII---FVAHRLSVAKQ-SDKIIVLDHGKIIEQGSHD 693
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
19-255 4.53e-20

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 89.60  E-value: 4.53e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrRRNRQVielgeqsasQM 98
Cdd:cd03253    5 NVTFAYDPGR-PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDG----QDIREV---------TL 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHVRGAdIAMIFQEpmtslNPVFTvgEQIAESIRLHQGASHEEAMVEAKRMLDQ----VRIPEA-KAILSRYPHQLSGGM 173
Cdd:cd03253   71 DSLRRA-IGVVPQD-----TVLFN--DTIGYNIRYGRPDATDEEVIEAAKAAQIhdkiMRFPDGyDTIVGERGLKLSGGE 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 174 RQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVETGSV 253
Cdd:cd03253  143 KQRVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKGRT--TIVIAHRLSTIVN-ADKIIVLKDGRIVERGTH 219

                 ..
gi 949724212 254 EQ 255
Cdd:cd03253  220 EE 221
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
2-242 4.90e-20

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 93.89  E-value: 4.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    2 PHSDELDA----SDVLAVSNLNIAFEQeqqRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALS-LMHLIEQAGGEVSCD 76
Cdd:TIGR02857 307 PLAGKAPVtaapASSLEFSGVSVAYPG---RRPALRPVSFTVPPGERVALVGPSGAGKS-TLLNlLLGFVDPTEGSIAVN 382
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   77 emllrrrnrqvielGEQSASQMRHVRGADIAMIFQEPmtslnpvFTVGEQIAESIRLHQGASHEEAMVEAKRM-----LD 151
Cdd:TIGR02857 383 --------------GVPLADADADSWRDQIAWVPQHP-------FLFAGTIAENIRLARPDASDAEIREALERagldeFV 441
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  152 QVRIPEAKAILSRYPHQLSGGMRQRVMIAMALsCRPA-VLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMG 230
Cdd:TIGR02857 442 AALPQGLDTPIGEGGAGLSGGQAQRLALARAF-LRDApLLLLDEPTAHLDAETEAEVLEALRALAQGRT--VLLVTHRLA 518
                         250
                  ....*....|..
gi 949724212  231 VVADiADRVLVM 242
Cdd:TIGR02857 519 LAAL-ADRIVVL 529
cbiO PRK13644
energy-coupling factor transporter ATPase;
339-555 5.42e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 90.43  E-value: 5.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGqrIDTLAASKLQPLRRDIQFIFQDPYAsldprQ 418
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG--IDTGDFSKLQGIRKLVGIVFQNPET-----Q 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSILEPLRV---HGLLQGDAGSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:PRK13644  90 FVGRTVEEDLAFgpeNLCLPPIEIRKRVDRALAEIGL-EKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLD 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 496 VSIRGQIINLMLDLQRElGIAYLFISHDMAVVErISHRVAVMYLGQIVEIGTRRAVFENP 555
Cdd:PRK13644 169 PDSGIAVLERIKKLHEK-GKTIVYITHNLEELH-DADRIIVMDRGKIVLEGEPENVLSDV 226
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
22-246 6.48e-20

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 89.31  E-value: 6.48e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  22 FEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSC-DEMLLRRRNRQVielgeqsaSQMRH 100
Cdd:cd03267   27 FKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVaGLVPWKRRKKFL--------RRIGV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 101 VRGADIAMIFQEPmtslnpvftvgeqIAESIRLHQgASHEEAMVEAKRMLDQ-VRIPEAKAILSRYPHQLSGGMRQRVMI 179
Cdd:cd03267   99 VFGQKTQLWWDLP-------------VIDSFYLLA-AIYDLPPARFKKRLDElSELLDLEELLDTPVRQLSLGQRMRAEI 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 180 AMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:cd03267  165 AAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGR 231
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
314-547 6.85e-20

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 88.24  E-value: 6.85e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrSGILNRVTRevhaveNVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaa 393
Cdd:cd03369    7 IEVENLSVRY---APDLPPVLK------NVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTI-- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 sKLQPLRRDIQFIFQDPY-------ASLDPRQTvgYS---ILEPLRVHGllqgdAGSKrvawllervgllpehawryphe 463
Cdd:cd03369   76 -PLEDLRSSLTIIPQDPTlfsgtirSNLDPFDE--YSdeeIYGALRVSE-----GGLN---------------------- 125
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 464 FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMldlqREL--GIAYLFISHDMAVVERIShRVAVMYLGQ 541
Cdd:cd03369  126 LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTI----REEftNSTILTIAHRLRTIIDYD-KILVMDAGE 200

                 ....*.
gi 949724212 542 IVEIGT 547
Cdd:cd03369  201 VKEYDH 206
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
29-543 7.15e-20

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 93.05  E-value: 7.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDEMLLRRRN-RQVIELGeqsasqmrhvrgadI 106
Cdd:PRK11288  17 VKALDDISFDCRAGQVHALMGENGAGKS-TLLKILSGNYQPdAGSILIDGQEMRFAStTAALAAG--------------V 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 107 AMIFQEpmTSLNPVFTVgeqiAESIRLHQ-----GASHEEAMV-EAKRMLDQVRI---PEAKaiLSRyphqLSGGMRQRV 177
Cdd:PRK11288  82 AIIYQE--LHLVPEMTV----AENLYLGQlphkgGIVNRRLLNyEAREQLEHLGVdidPDTP--LKY----LSIGQRQMV 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 178 MIAMALScRPAVLIA-DEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVADIADRVLVMYQGEAVET-GSVEQ 255
Cdd:PRK11288 150 EIAKALA-RNARVIAfDEPTSSLSAREIEQLFRVIRELRAEGRV-ILYVSHRMEEIFALCDAITVFKDGRYVATfDDMAQ 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 256 IFHApqhpytkallaavpQL-GAMNGHElprrfplisLHDPSHVEPQTeqdtvvEGEPILRVRNLVTRfPLRsgilnrvt 334
Cdd:PRK11288 228 VDRD--------------QLvQAMVGRE---------IGDIYGYRPRP------LGEVRLRLDGLKGP-GLR-------- 269
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 335 revhavENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlAASKLQPLRRDIQFIFQDPYA-S 413
Cdd:PRK11288 270 ------EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPID--IRSPRDAIRAGIMLCPEDRKAeG 341
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDPRQTVGYSILEPLRVH----GLLQGDAGSKRVAwlLERVGLL------PEHAWRYpheFSGGQRQRICIARALALNPK 483
Cdd:PRK11288 342 IIPVHSVADNINISARRHhlraGCLINNRWEAENA--DRFIRSLniktpsREQLIMN---LSGGNQQKAILGRWLSEDMK 416
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 484 VIIADESVSALDVSIRGQIINLMLDLQrELGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:PRK11288 417 VILLDEPTRGIDVGAKHEIYNVIYELA-AQGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
12-259 8.20e-20

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 92.77  E-value: 8.20e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNiafeqeqqRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRN-RQVIEL 90
Cdd:COG1129  256 VLEVEGLS--------VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSpRDAIRA 327
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 GeqsasqmrhvrgadIAMIfqeP----MTSLNPVFTVGEQIAESI--RLHQGA--SHEEAMVEAKRMLDQVRI----PEA 158
Cdd:COG1129  328 G--------------IAYV---PedrkGEGLVLDLSIRENITLASldRLSRGGllDRRRERALAEEYIKRLRIktpsPEQ 390
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 159 KAIlsryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADR 238
Cdd:COG1129  391 PVG------NLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDR 463
                        250       260
                 ....*....|....*....|....*.
gi 949724212 239 VLVMYQGEAV-----ETGSVEQIFHA 259
Cdd:COG1129  464 ILVMREGRIVgeldrEEATEEAIMAA 489
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
31-251 8.24e-20

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 88.02  E-value: 8.24e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGeTLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGEQSASQMRHVRGADIAMIF 110
Cdd:cd03264   15 ALDGVSLTLGPG-MYGLLGPNGAGKT----TLMRIL--AT---------LTPPSSGTIRIDGQDVLKQPQKLRRRIGYLP 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMTSlnPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:cd03264   79 QEFGVY--PNFTVREFLDYIAWLK-GIPSKEVKARVDEVLELVNLGDRA---KKKIGSLSGGMRRRVGIAQALVGDPSIL 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03264  153 IVDEPTAGLDPEERIRFRNLLSELGEDRI--VILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
336-547 8.37e-20

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 93.85  E-value: 8.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLA----ASKLQPLRRDIqFIFQ--- 408
Cdd:TIGR03796 491 EPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPrevlANSVAMVDQDI-FLFEgtv 569
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  409 -DPYASLDPrqtvgySILEPlrvhGLLQgdagSKRVAWLLERVGLLPEhawRYPHE-------FSGGQRQRICIARALAL 480
Cdd:TIGR03796 570 rDNLTLWDP------TIPDA----DLVR----ACKDAAIHDVITSRPG---GYDAElaegganLSGGQRQRLEIARALVR 632
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212  481 NPKVIIADESVSALDVSIRGQII-NLmldlqRELGIAYLFISHDMAVVeRISHRVAVMYLGQIVEIGT 547
Cdd:TIGR03796 633 NPSILILDEATSALDPETEKIIDdNL-----RRRGCTCIIVAHRLSTI-RDCDEIIVLERGKVVQRGT 694
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
338-548 1.11e-19

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 88.35  E-value: 1.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASklQPLRRDIQF------IFqdpy 411
Cdd:TIGR03410  14 HILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPH--ERARAGIAYvpqgreIF---- 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  412 asldPRQTVgysiLEPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:TIGR03410  88 ----PRLTV----EENLLTGLAALPRRSRKIPDEIYELFPVLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPT 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212  492 SALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTR 548
Cdd:TIGR03410 160 EGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAG 216
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
27-259 1.16e-19

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 88.60  E-value: 1.16e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  27 QRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLM-HLIEQAGGEVscdemllrrrnrqvielgeqsasqmrHVRGAD 105
Cdd:COG1134   37 EEFWALKDVSFEVERGESVGIIGRNGAGKS-TLLKLIaGILEPTSGRV--------------------------EVNGRV 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 IAMIfqEPMTSLNPVFTVGEQIAESIRLHqGASHEEAmveaKRMLDQVripEAKAILSRYPHQ----LSGGMRQRVMIAM 181
Cdd:COG1134   90 SALL--ELGAGFHPELTGRENIYLNGRLL-GLSRKEI----DEKFDEI---VEFAELGDFIDQpvktYSSGMRARLAFAV 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHA 259
Cdd:COG1134  160 ATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVIAA 236
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
336-556 1.20e-19

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 91.24  E-value: 1.20e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKlqplrRDIQFIFQDpYAsLD 415
Cdd:PRK11000  15 DVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE-----RGVGMVFQS-YA-LY 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILEPLRVHGLLQGDAgSKRV---AWLLERVGLLPehawRYPHEFSGGQRQRICIARALALNPKVIIADESVS 492
Cdd:PRK11000  88 PHLSVAENMSFGLKLAGAKKEEI-NQRVnqvAEVLQLAHLLD----RKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLS 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 493 ALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK11000 163 NLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPA 226
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
31-245 1.34e-19

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 88.01  E-value: 1.34e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQ--AGGEVSCDEMLLRRRNRQVIELGEQsasqmrhvrgadIAM 108
Cdd:PRK10908  17 ALQGVTFHMRPGEMAFLTGHSGAGKS-TLLKLICGIERpsAGKIWFSGHDITRLKNREVPFLRRQ------------IGM 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPMTSLNPvfTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEaKAilSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK10908  84 IFQDHHLLMDR--TVYDNVAIPLII-AGASGDDIRRRVSAALDKVGLLD-KA--KNFPIQLSGGEQQRVGIARAVVNKPA 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQG 245
Cdd:PRK10908 158 VLLADEPTGNLDDALSEGILRLFEEFNR-VGVTVLMATHDIGLISRRSYRMLTLSDG 213
MsbA_rel TIGR02204
ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ...
336-552 1.87e-19

ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ATP transporter that exports lipid A and to eukaryotic P-glycoproteins.


Pssm-ID: 131259 [Multi-domain]  Cd Length: 576  Bit Score: 92.07  E-value: 1.87e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQPLRRDIQFIFQDPYA-SL 414
Cdd:TIGR02204 352 DQPALDGLNLTVRPGETVALVGPSGAGKSTLFQLLLRFYDPQSGRILLDGVDL---RQLDPAELRARMALVPQDPVLfAA 428
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  415 DPRQTVGYSileplRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHE----FSGGQRQRICIARALALNPKVIIADES 490
Cdd:TIGR02204 429 SVMENIRYG-----RPDATDEEVEAAARAAHAHEFISALPEGYDTYLGErgvtLSGGQRQRIAIARAILKDAPILLLDEA 503
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212  491 VSALDvSIRGQIINLMLDLQRElGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGTRRAVF 552
Cdd:TIGR02204 504 TSALD-AESEQLVQQALETLMK-GRTTLIIAHRLATVLK-ADRIVVMDQGRIVAQGTHAELI 562
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
344-543 2.29e-19

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 87.33  E-value: 2.29e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 344 SFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQriDTLAASklqPLRRDIQFIFQDP--YASLDPR 417
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKST----LLNLIagflTPASGSLTLNGQ--DHTTTP---PSRRPVSMLFQENnlFSHLTVA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSiLEPlrvhGLLQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PRK10771  90 QNIGLG-LNP----GLKLNAAQREKLHAIARQMGIE-DLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPA 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 949724212 498 IRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:PRK10771 164 LRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIA 209
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
311-542 2.82e-19

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 87.14  E-value: 2.82e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPLRSgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdt 390
Cdd:cd03248    9 KGIVKFQNVTFAYPTRP--------DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPI-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 lAASKLQPLRRDIQFIFQDPyasldprQTVGYSILEPLrVHGLLQGDAGS-KRVAWLLERVGLLPEHAWRYPHE------ 463
Cdd:cd03248   79 -SQYEHKYLHSKVSLVGQEP-------VLFARSLQDNI-AYGLQSCSFECvKEAAQKAHAHSFISELASGYDTEvgekgs 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 464 -FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELgiAYLFISHDMAVVERiSHRVAVMYLGQI 542
Cdd:cd03248  150 qLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERR--TVLVIAHRLSTVER-ADQILVLDGGRI 226
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
336-546 3.30e-19

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 85.44  E-value: 3.30e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASklqpLRRDIQFIFQDPYasld 415
Cdd:cd03247   14 EQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKA----LSSLISVLNQRPY---- 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 prqtvgysileplrvhgLLQGDagskrvawLLERVGLlpehawryphEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:cd03247   86 -----------------LFDTT--------LRNNLGR----------RFSGGERQRLALARILLQDAPIVLLDEPTVGLD 130
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 949724212 496 VSIRGQIINLMLDLQRELGIayLFISHDMAVVERIShRVAVMYLGQIVEIG 546
Cdd:cd03247  131 PITERQLLSLIFEVLKDKTL--IWITHHLTGIEHMD-KILFLENGKIIMQG 178
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
13-242 3.77e-19

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 86.38  E-value: 3.77e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAfeqeQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLM--HLIE--QAGGEVSCDEmllRRRNRQVI 88
Cdd:COG4136    2 LSLENLTIT----LGGRPLLAPLSLTVAPGEILTLMGPSGSGKS-TLLAAIagTLSPafSASGEVLLNG---RRLTALPA 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELgeqsasqmRHvrgadIAMIFQEPMtsLNPVFTVGEQIAESIRLHQGASHEEAMVEAkrMLDQVRIPeakAILSRYPHQ 168
Cdd:COG4136   74 EQ--------RR-----IGILFQDDL--LFPHLSVGENLAFALPPTIGRAQRRARVEQ--ALEEAGLA---GFADRDPAT 133
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDmgvVADI--ADRVLVM 242
Cdd:COG4136  134 LSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHD---EEDApaAGRVLDL 206
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
22-256 5.55e-19

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 88.22  E-value: 5.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  22 FEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEVSCDEMLLRRRnrqvielgeqsasQMRH 100
Cdd:COG4586   28 FRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKS-TTIKMLTgILVPTSGEVRVLGYVPFKR-------------RKEF 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 101 VRgaDIAMIF-QEpmTSLN---PVftvgeqiAESIRLHQ------GASHEEAMVEAKRMLD-------QVRipeakails 163
Cdd:COG4586   94 AR--RIGVVFgQR--SQLWwdlPA-------IDSFRLLKaiyripDAEYKKRLDELVELLDlgelldtPVR--------- 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 164 ryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMY 243
Cdd:COG4586  154 ----QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVID 229
                        250
                 ....*....|...
gi 949724212 244 QGEAVETGSVEQI 256
Cdd:COG4586  230 HGRIIYDGSLEEL 242
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
330-546 8.29e-19

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 85.30  E-value: 8.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  330 LNRVTREVHAvENVSFDLW--PGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAasklqPLRRDIQFIF 407
Cdd:TIGR01277   3 LDKVRYEYEH-LPMEFDLNvaDGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLA-----PYQRPVSMLF 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  408 QDP--YASLDPRQTVGYSILEPLRVHGLLQgdagsKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVI 485
Cdd:TIGR01277  77 QENnlFAHLTVRQNIGLGLHPGLKLNAEQQ-----EKVVDAAQQVGI-ADYLDRLPEQLSGGQRQRVALARCLVRPNPIL 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212  486 IADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:TIGR01277 151 LLDEPFSALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
2-245 1.01e-18

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 89.68  E-value: 1.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   2 PHSDELDASDVLAVSNLNiafeqeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQA----GGEVSCDE 77
Cdd:PRK10762 247 PRLDKAPGEVRLKVDNLS---------GPGVNDVSFTLRKGEILGVSGLMGAGRT----ELMKVLYGAlprtSGYVTLDG 313
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  78 MLLRRRNRQ-VIELGEQSASQMRHVRGADIAMIFQEPM--TSLNPVFTVGEQIAesirlHQgasHEEAMVEAKRMLDQVR 154
Cdd:PRK10762 314 HEVVTRSPQdGLANGIVYISEDRKRDGLVLGMSVKENMslTALRYFSRAGGSLK-----HA---DEQQAVSDFIRLFNIK 385
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 155 IPEAKAILSryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVAD 234
Cdd:PRK10762 386 TPSMEQAIG----LLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLG 460
                        250
                 ....*....|.
gi 949724212 235 IADRVLVMYQG 245
Cdd:PRK10762 461 MSDRILVMHEG 471
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
13-257 1.47e-18

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 89.42  E-value: 1.47e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQviELGe 92
Cdd:COG4618  331 LSVENLTVVPPGSKRPI--LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDRE--ELG- 405
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 qsasqmRHVrG---ADIAMifqepmtslnpvF--TVGEQIAesiRLhqGASHEEAMVEAKRMldqVRIPEAkaILsRYP- 166
Cdd:COG4618  406 ------RHI-GylpQDVEL------------FdgTIAENIA---RF--GDADPEKVVAAAKL---AGVHEM--IL-RLPd 455
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 ----------HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmsmG--VIFITHDMGVVAd 234
Cdd:COG4618  456 gydtrigeggARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKAR---GatVVVITHRPSLLA- 531
                        250       260
                 ....*....|....*....|...
gi 949724212 235 IADRVLVMYQGEAVETGSVEQIF 257
Cdd:COG4618  532 AVDKLLVLRDGRVQAFGPRDEVL 554
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
349-534 1.54e-18

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 84.83  E-value: 1.54e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 349 PGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLR-RDIQFIFQDpyASLDPRQTVgysiLEP 427
Cdd:PRK10584  35 RGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRaKHVGFVFQS--FMLIPTLNA----LEN 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 428 LRVHGLLQGDAGSK---RVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIIN 504
Cdd:PRK10584 109 VELPALLRGESSRQsrnGAKALLEQLGL-GKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIAD 187
                        170       180       190
                 ....*....|....*....|....*....|
gi 949724212 505 LMLDLQRELGIAYLFISHDMAVVERISHRV 534
Cdd:PRK10584 188 LLFSLNREHGTTLILVTHDLQLAARCDRRL 217
type_I_sec_HlyB TIGR01846
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...
340-547 1.66e-18

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273831 [Multi-domain]  Cd Length: 694  Bit Score: 89.42  E-value: 1.66e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridTLAASKLQPLRRDIQFIFQDPYasLDPRqt 419
Cdd:TIGR01846 473 LSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGV---DLAIADPAWLRRQMGVVLQENV--LFSR-- 545
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  420 vgySILEPLRvhgLLQGDAGSKRVAWLLERVGLLpEHAWRYPHEF-----------SGGQRQRICIARALALNPKVIIAD 488
Cdd:TIGR01846 546 ---SIRDNIA---LCNPGAPFEHVIHAAKLAGAH-DFISELPQGYntevgekganlSGGQRQRIAIARALVGNPRILIFD 618
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212  489 ESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMAVVeRISHRVAVMYLGQIVEIGT 547
Cdd:TIGR01846 619 EATSALDYESEALIMRNMREICR--GRTVIIIAHRLSTV-RACDRIIVLEKGQIAESGR 674
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
309-550 1.72e-18

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 88.93  E-value: 1.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 309 EGEPILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRI 388
Cdd:COG3845    1 MMPPALELRGITKRFG-----------GVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPV 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 389 DtlAASKLQPLRRDIQFIFQDPyaSLDPRQTV------GysiLEPLRvHGLLQGDAGSKRVAWLLERVGL-LPEHAwrYP 461
Cdd:COG3845   70 R--IRSPRDAIALGIGMVHQHF--MLVPNLTVaenivlG---LEPTK-GGRLDRKAARARIRELSERYGLdVDPDA--KV 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 HEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQ 541
Cdd:COG3845  140 EDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADRVTVLRRGK 218

                 ....*....
gi 949724212 542 IVeiGTRRA 550
Cdd:COG3845  219 VV--GTVDT 225
cbiO PRK13644
energy-coupling factor transporter ATPase;
31-260 1.95e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 85.81  E-value: 1.95e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemLLRRrnrqvIELGEqsASQMRHVRGAdIAMIF 110
Cdd:PRK13644  17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKV-----LVSG-----IDTGD--FSKLQGIRKL-VGIVF 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMTSLnpvftVGEQIAESIrlhqgASHEEAM----VEAKRMLDQVrIPEAKAILSRY--PHQLSGGMRQRVMIAMALS 184
Cdd:PRK13644  84 QNPETQF-----VGRTVEEDL-----AFGPENLclppIEIRKRVDRA-LAEIGLEKYRHrsPKTLSGGQGQCVALAGILT 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 185 CRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADiADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK13644 153 MEPECLIFDEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVLSDV 226
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
334-555 2.18e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 85.62  E-value: 2.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 334 TREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQPLRRDIQFIFQDP--- 410
Cdd:PRK13652  14 SGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPI---TKENIREVRKFVGLVFQNPddq 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 411 YASLDPRQTVGYSilePLRVHglLQGDAGSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADES 490
Cdd:PRK13652  91 IFSPTVEQDIAFG---PINLG--LDEETVAHRVSSALHMLGL-EELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEP 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 491 VSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENP 555
Cdd:PRK13652 165 TAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
314-555 2.81e-18

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 84.13  E-value: 2.81e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:cd03218    1 LRAENLSKRYG---------KRKV--VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPM 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQplRRDIQFIFQDpyASLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlpEH-AWRYPHEFSGGQRQRI 472
Cdd:cd03218   70 HKRA--RLGIGYLPQE--ASIFRKLTVEENILAVLEIRGLSKKER-EEKLEELLEEFHI--THlRKSKASSLSGGERRRV 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 473 CIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVF 552
Cdd:cd03218  143 EIARALATNPKFLLLDEPFAGVDPIAVQDIQKIIKIL-KDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221

                 ...
gi 949724212 553 ENP 555
Cdd:cd03218  222 ANE 224
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
31-229 2.84e-18

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 84.75  E-value: 2.84e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIE-----QAGgevscdemllrrrnrqVIELGEQSASQmrhvRGAD 105
Cdd:PRK11248  16 ALEDINLTLESGELLVVLGPSGCGKT----TLLNLIAgfvpyQHG----------------SITLDGKPVEG----PGAE 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 IAMIFQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKAilsRYPHQLSGGMRQRVMIAMALSC 185
Cdd:PRK11248  72 RGVVFQN--EGLLPWRNVQDNVAFGLQL-AGVEKMQRLEIAHQMLKKVGLEGAEK---RYIWQLSGGQRQRVGIARALAA 145
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 949724212 186 RPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDM 229
Cdd:PRK11248 146 NPQLLLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDI 189
NHLM_micro_ABC2 TIGR03797
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...
341-547 3.46e-18

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274789 [Multi-domain]  Cd Length: 686  Bit Score: 88.47  E-value: 3.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  341 ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPyasldprQTV 420
Cdd:TIGR03797 470 DDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAGL---DVQAVRRQLGVVLQNG-------RLM 539
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  421 GYSILEPLRVHGLLQGDAgskrvAWLLERVGLLPEHAWRYP---H--------EFSGGQRQRICIARALALNPKVIIADE 489
Cdd:TIGR03797 540 SGSIFENIAGGAPLTLDE-----AWEAARMAGLAEDIRAMPmgmHtvisegggTLSGGQRQRLLIARALVRKPRILLFDE 614
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212  490 SVSALDVsiRGQIInLMLDLQReLGIAYLFISHDMAVVeRISHRVAVMYLGQIVEIGT 547
Cdd:TIGR03797 615 ATSALDN--RTQAI-VSESLER-LKVTRIVIAHRLSTI-RNADRIYVLDAGRVVQQGT 667
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
168-547 4.01e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 88.64  E-value: 4.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDM-SMGVIFITHDMgvvaDIADR---VLVMY 243
Cdd:NF033858 136 KLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVLVATAYM----EEAERfdwLVAMD 211
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 244 QGEAVETGSveqifhapqhpyTKALLAavpQLGAMNgheLPRRFplISL--------HDPSHVEPQTEQDtvvEGEPILR 315
Cdd:NF033858 212 AGRVLATGT------------PAELLA---RTGADT---LEAAF--IALlpeekrrgHQPVVIPPRPADD---DDEPAIE 268
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 316 VRNLVTRFplrsGilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTlaask 395
Cdd:NF033858 269 ARGLTMRF----G-------DFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDA----- 332
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 396 lqplrRDIqfifqdpyaslDPRQTVGY-----------SILEPLRVHGLL---QGDAGSKRVAWLLERVGLLpEHAWRYP 461
Cdd:NF033858 333 -----GDI-----------ATRRRVGYmsqafslygelTVRQNLELHARLfhlPAAEIAARVAEMLERFDLA-DVADALP 395
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 HEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAyLFIS-HDMAVVERIShRVAVMYLG 540
Cdd:NF033858 396 DSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVT-IFIStHFMNEAERCD-RISLMHAG 473

                 ....*..
gi 949724212 541 QIVEIGT 547
Cdd:NF033858 474 RVLASDT 480
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
32-257 4.33e-18

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 83.98  E-value: 4.33e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSvTALSL------------MHLIEQAGGEVSCDEmlLRRRnrqvieLGeqsasqmr 99
Cdd:COG1119   19 LDDISWTVKPGEHWAILGPNGAGKS-TLLSLitgdlpptygndVRLFGERRGGEDVWE--LRKR------IG-------- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 100 HVrGADIAMIFQEPMTSLNPV---FTvgeqiaESIRLHQGASHEEAMvEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQR 176
Cdd:COG1119   82 LV-SPALQLRFPRDETVLDVVlsgFF------DSIGLYREPTDEQRE-RARELLELLGL---AHLADRPFGTLSQGEQRR 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDmgvVADIAD---RVLVMYQGEAVETGSV 253
Cdd:COG1119  151 VLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHH---VEEIPPgitHVLLLKDGRVVAAGPK 227

                 ....
gi 949724212 254 EQIF 257
Cdd:COG1119  228 EEVL 231
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
31-252 5.18e-18

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 83.31  E-value: 5.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIelgeqsasqmrhvRGAdIAMIF 110
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL-------------RSR-ISIIP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMT-------SLNP--VFTvGEQIAESIRLHQGASHeeamVEAKRMLDQVRIPEAKAilsryphQLSGGMRQRVMIAM 181
Cdd:cd03244   85 QDPVLfsgtirsNLDPfgEYS-DEELWQALERVGLKEF----VESLPGGLDTVVEEGGE-------NLSVGQRQLLCLAR 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVETGS 252
Cdd:cd03244  153 ALLRKSKILVLDEATASVDPETDALIQKTIREAFKDCT--VLTIAHRLDTIID-SDRILVLDKGRVVEFDS 220
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
13-247 5.40e-18

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 81.88  E-value: 5.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQviELGE 92
Cdd:cd03246    1 LEVENVSFRYPGAEPPV--LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPN--ELGD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVrgadiaMIFqepmtslnpvftvGEQIAESIrlhqgasheeamveakrmldqvripeakailsryphqLSGG 172
Cdd:cd03246   77 HVGYLPQDD------ELF-------------SGSIAENI-------------------------------------LSGG 100
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVAdIADRVLVMYQGEA 247
Cdd:cd03246  101 QRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAGAT-RIVIAHRPETLA-SADRILVLEDGRV 173
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
350-542 6.19e-18

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 83.96  E-value: 6.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 350 GETLSLVGESGCGKSTTGRALLRLVESQRGEIifngqridtLAASK-LQPLRRDIQFIFQDpyASLDPRQTVGYSIlepl 428
Cdd:PRK11247  38 GQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL---------LAGTApLAEAREDTRLMFQD--ARLLPWKKVIDNV---- 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 429 rvhGLlqGDAGSKRVAWL--LERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLM 506
Cdd:PRK11247 103 ---GL--GLKGQWRDAALqaLAAVGL-ADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLI 176
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 949724212 507 LDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:PRK11247 177 ESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
12-257 8.71e-18

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 83.90  E-value: 8.71e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIELG 91
Cdd:PRK13638   1 MLATSDLWFRYQDEP----VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLALR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQsasqmrhvrgadIAMIFQEPMTSLnpVFT-VGEQIAESIRlHQGASHEEAmveAKRMLDQVRIPEAKailsRYPHQ-- 168
Cdd:PRK13638  77 QQ------------VATVFQDPEQQI--FYTdIDSDIAFSLR-NLGVPEAEI---TRRVDEALTLVDAQ----HFRHQpi 134
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 --LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIK-VLQQDMSmgVIFITHDMGVVADIADRVLVMYQG 245
Cdd:PRK13638 135 qcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRrIVAQGNH--VIISSHDIDLIYEISDAVYVLRQG 212
                        250
                 ....*....|..
gi 949724212 246 EAVETGSVEQIF 257
Cdd:PRK13638 213 QILTHGAPGEVF 224
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
36-256 8.93e-18

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 82.71  E-value: 8.93e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  36 SFRLKRGETLAIVGESGSGKSvTALSLMH-LIEQAGGEvscdeMLLRRRNRQvielgEQSASQmRHVrgadiAMIFQEpm 114
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKS-TLLNLIAgFLTPASGS-----LTLNGQDHT-----TTPPSR-RPV-----SMLFQE-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 115 TSLNPVFTVGEQIAesIRLHQG----ASHEEAMveaKRMLDQVRIPEakaILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
Cdd:PRK10771  80 NNLFSHLTVAQNIG--LGLNPGlklnAAQREKL---HAIARQMGIED---LLARLPGQLSGGQRQRVALARCLVREQPIL 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 191 IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:PRK10771 152 LLDEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDEL 217
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
12-246 9.00e-18

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 86.52  E-value: 9.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNiAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIE-QAGGEVSCDEMLLRRRN-RQVIE 89
Cdd:PRK13549 259 ILEVRNLT-AWDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRNpQQAIA 337
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGeqsasqmrhvrgadIAMIFQE-PMTSLNPVFTVGEQIAESI--------RLHQGASHEEAMVEAKRMldQVRIPEAKA 160
Cdd:PRK13549 338 QG--------------IAMVPEDrKRDGIVPVMGVGKNITLAAldrftggsRIDDAAELKTILESIQRL--KVKTASPEL 401
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRyphqLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVL 240
Cdd:PRK13549 402 AIAR----LSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQ-QGVAIIVISSELPEVLGLSDRVL 476

                 ....*.
gi 949724212 241 VMYQGE 246
Cdd:PRK13549 477 VMHEGK 482
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
16-522 9.36e-18

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 86.61  E-value: 9.36e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  16 SNLNIAfeQEQQRVSAVRNL---SFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemlLRRRNRQVIELGE 92
Cdd:PRK10938   2 SSLQIS--QGTFRLSDTKTLqlpSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQ---FSHITRLSFEQLQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVRGADiamifqepMTSLNPVFTvGEQIAESIRLHqgaSHEEAMVEakRMLDQVRIpeaKAILSRYPHQLSGG 172
Cdd:PRK10938  77 KLVSDEWQRNNTD--------MLSPGEDDT-GRTTAEIIQDE---VKDPARCE--QLAQQFGI---TALLDRRFKYLSTG 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAVETGS 252
Cdd:PRK10938 140 ETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLADCTLAETGE 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 253 VEQIFhapqhpyTKALLAAVPQLGAMNGHELPRRFplislhDPSHvepqteQDTVVEGEPILRVRNLVTRFPLRSgILNR 332
Cdd:PRK10938 219 REEIL-------QQALVAQLAHSEQLEGVQLPEPD------EPSA------RHALPANEPRIVLNNGVVSYNDRP-ILHN 278
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 333 VTREVHavenvsfdlwPGETLSLVGESGCGKSTtgraLLRLVES---------------QR--GEIIFN-GQRIDTLAAS 394
Cdd:PRK10938 279 LSWQVN----------PGEHWQIVGPNGAGKST----LLSLITGdhpqgysndltlfgrRRgsGETIWDiKKHIGYVSSS 344
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 395 klqplrrdiqfIFQDPYASLDPRQTV--GY--SIleplrvhGLLQG--DAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQ 468
Cdd:PRK10938 345 -----------LHLDYRVSTSVRNVIlsGFfdSI-------GIYQAvsDRQQKLAQQWLDILGIDKRTADAPFHSLSWGQ 406
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 469 RQRICIARALALNPKVIIADESVSALDVSIRgQIINLMLD-LQRELGIAYLFISH 522
Cdd:PRK10938 407 QRLALIVRALVKHPTLLILDEPLQGLDPLNR-QLVRRFVDvLISEGETQLLFVSH 460
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
340-522 1.24e-17

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 80.66  E-value: 1.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFngqridtlaasklqPLRRDIQFIFQDPYASLdprqt 419
Cdd:cd03223   17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM--------------PEGEDLLFLPQRPYLPL----- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 vgysileplrvhgllqgdagskrvawllervGLLPEhAWRYP--HEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:cd03223   78 -------------------------------GTLRE-QLIYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEE 125
                        170       180
                 ....*....|....*....|....*
gi 949724212 498 IRGQiinlMLDLQRELGIAYLFISH 522
Cdd:cd03223  126 SEDR----LYQLLKELGITVISVGH 146
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
336-555 1.88e-17

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 86.31  E-value: 1.88e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPyasLD 415
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQY---DHHYLHRQVALVGQEP---VL 566
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  416 PRQTVGYSILEPLRVHGLLQGDAGSKRvAWLLERVGLLP--------EHAwrypHEFSGGQRQRICIARALALNPKVIIA 487
Cdd:TIGR00958 567 FSGSVRENIAYGLTDTPDEEIMAAAKA-ANAHDFIMEFPngydtevgEKG----SQLSGGQKQRIAIARALVRKPRVLIL 641
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212  488 DESVSALDVsirgQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQIVEIGTRRAVFENP 555
Cdd:TIGR00958 642 DEATSALDA----ECEQLLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQ 704
cbiO PRK13643
energy-coupling factor transporter ATPase;
339-553 2.02e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 83.24  E-value: 2.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASK-LQPLRRDIQFIFQDPYASLDpR 417
Cdd:PRK13643  21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKeIKPVRKKVGVVFQFPESQLF-E 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PRK13643 100 ETVLKDVAFGPQNFGIPKEKA-EKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPK 178
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 498 IRGQIINLMLDLQrELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:PRK13643 179 ARIEMMQLFESIH-QSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQ 233
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
19-266 2.03e-17

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 82.39  E-value: 2.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQAGGEVscdemllrrRNRQVIELGEQSASQM 98
Cdd:PRK14258  12 NLSFYYDTQKI--LEGVSMEIYQSKVTAIIGPSGCGKS-TFLKCLNRMNELESEV---------RVEGRVEFFNQNIYER 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 R----HVRgADIAMIFQEPmtSLNPVfTVGEQIAESIRL---HQGASHE---EAMVEAKRMLDQVRIPEAKAILsryphQ 168
Cdd:PRK14258  80 RvnlnRLR-RQVSMVHPKP--NLFPM-SVYDNVAYGVKIvgwRPKLEIDdivESALKDADLWDEIKHKIHKSAL-----D 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEA- 247
Cdd:PRK14258 151 LSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENr 230
                        250       260
                 ....*....|....*....|...
gi 949724212 248 ----VETGSVEQIFHAPQHPYTK 266
Cdd:PRK14258 231 igqlVEFGLTKKIFNSPHDSRTR 253
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
340-552 2.69e-17

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 82.36  E-value: 2.69e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtLAASKLQPLRRDIQFIFQDP-----YASL 414
Cdd:PRK13638  17 LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLD-YSKRGLLALRQQVATVFQDPeqqifYTDI 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DprQTVGYSilepLRVHGLLQGDAgSKRVAWLLERVgllpeHAWRYPHE----FSGGQRQRICIARALALNPKVIIADES 490
Cdd:PRK13638  96 D--SDIAFS----LRNLGVPEAEI-TRRVDEALTLV-----DAQHFRHQpiqcLSHGQKKRVAIAGALVLQARYLLLDEP 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 491 VSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVF 552
Cdd:PRK13638 164 TAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVF 224
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
13-252 3.16e-17

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 80.53  E-value: 3.16e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrNRQVIELGE 92
Cdd:cd03369    7 IEVENLSVRYAPDLPPV--LKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGI-----DISTIPLED 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASqmrhvrgadIAMIFQEPM-------TSLNPV--FTvGEQIAESIRLHQGASHeeamveakrmldqvripeakails 163
Cdd:cd03369   80 LRSS---------LTIIPQDPTlfsgtirSNLDPFdeYS-DEEIYGALRVSEGGLN------------------------ 125
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 164 ryphqLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgvIFITHDMGVVADIaDRVLVMY 243
Cdd:cd03369  126 -----LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREEFTNSTI--LTIAHRLRTIIDY-DKILVMD 197

                 ....*....
gi 949724212 244 QGEAVETGS 252
Cdd:cd03369  198 AGEVKEYDH 206
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
311-543 3.61e-17

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 84.84  E-value: 3.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDT 390
Cdd:PRK09700   3 TPYISMAGIGKSFG-----------PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNK 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LA---ASKLqplrrDIQFIFQDpYASLDPrqtvgYSILEPLRVHGLLQGDAGS----------KRVAWLLERVGLLpeha 457
Cdd:PRK09700  72 LDhklAAQL-----GIGIIYQE-LSVIDE-----LTVLENLYIGRHLTKKVCGvniidwremrVRAAMMLLRVGLK---- 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 458 wRYPHEFSG----GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHR 533
Cdd:PRK09700 137 -VDLDEKVAnlsiSHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDR 214
                        250
                 ....*....|
gi 949724212 534 VAVMYLGQIV 543
Cdd:PRK09700 215 YTVMKDGSSV 224
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
29-260 3.95e-17

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 83.35  E-value: 3.95e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAG------GEVSCDEmllRRRNRqvIELGEQsasqmrhvr 102
Cdd:PRK11650  17 TQVIKGIDLDVADGEFIVLVGPSGCGKS----TLLRMV--AGleritsGEIWIGG---RVVNE--LEPADR--------- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 103 gaDIAMIFQEpmTSLNPVFTVGEQIAESIRLhQGASHEEAmveAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMA 182
Cdd:PRK11650  77 --DIAMVFQN--YALYPHMSVRENMAYGLKI-RGMPKAEI---EERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRA 148
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 183 LSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK11650 149 IVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKP 226
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
19-256 4.20e-17

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 84.77  E-value: 4.20e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQSASQM 98
Cdd:TIGR02203 335 NVTFRYPGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDG----------HDLADYTLASL 404
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   99 RhvrgADIAMIFQEpmtslnpVFTVGEQIAESIRLHQGASHEEAMVEakrmlDQVRIPEAKAILSRYP---HQ------- 168
Cdd:TIGR02203 405 R----RQVALVSQD-------VVLFNDTIANNIAYGRTEQADRAEIE-----RALAAAYAQDFVDKLPlglDTpigengv 468
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  169 -LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEA 247
Cdd:TIGR02203 469 lLSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQGRT--TLVIAHRLSTIEK-ADRIVVMDDGRI 545

                  ....*....
gi 949724212  248 VETGSVEQI 256
Cdd:TIGR02203 546 VERGTHNEL 554
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
35-272 4.31e-17

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 81.04  E-value: 4.31e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  35 LSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQAGGEVscdemLLRRRNrqvieLGEQSASQMRHVRgadiAMIFQEPM 114
Cdd:COG4138   15 ISAQVNAGELIHLIGPNGAGKS-TLLARMAGLLPGQGEI-----LLNGRP-----LSDWSAAELARHR----AYLSQQQS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 115 TSLN-PVFtvgeqiaESIRLHQGASHEEAMVEA--KRMLDQVRIpEAKaiLSRYPHQLSGGMRQRVMIAMAL-----SCR 186
Cdd:COG4138   80 PPFAmPVF-------QYLALHQPAGASSEAVEQllAQLAEALGL-EDK--LSRPLTQLSGGEWQRVRLAAVLlqvwpTIN 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 187 P--AVLIADEPTTALDVTIQAQILQLIKVL-QQDMSmgVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFhapqhp 263
Cdd:COG4138  150 PegQLLLLDEPMNSLDVAQQAALDRLLRELcQQGIT--VVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVM------ 221

                 ....*....
gi 949724212 264 yTKALLAAV 272
Cdd:COG4138  222 -TPENLSEV 229
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
334-553 4.49e-17

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 84.69  E-value: 4.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 334 TREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPYAS 413
Cdd:PRK11176 353 GKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDY---TLASLRNQVALVSQNVHLF 429
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDprqTVGYSIleplrvhgllqgdAGSKRVAWLLERVgllpEHAWRYPH--EF-------------------SGGQRQRI 472
Cdd:PRK11176 430 ND---TIANNI-------------AYARTEQYSREQI----EEAARMAYamDFinkmdngldtvigengvllSGGQRQRI 489
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 473 CIARALALNPKVIIADESVSALDV-SIRgqIINLMLD-LQRELGIayLFISHDMAVVERiSHRVAVMYLGQIVEIGTRRA 550
Cdd:PRK11176 490 AIARALLRDSPILILDEATSALDTeSER--AIQAALDeLQKNRTS--LVIAHRLSTIEK-ADEILVVEDGEIVERGTHAE 564

                 ...
gi 949724212 551 VFE 553
Cdd:PRK11176 565 LLA 567
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
12-256 4.72e-17

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 84.71  E-value: 4.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   12 VLAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNR------ 85
Cdd:TIGR01842 316 HLSVENVTIVPPGGKKPT--LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRetfgkh 393
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   86 -----QVIELGEQSASQmrhvrgaDIAMiFQEPMTSlnpvftvgEQIAESIRLHQgaSHEeaMVEAKRMLDQVRIPEAKA 160
Cdd:TIGR01842 394 igylpQDVELFPGTVAE-------NIAR-FGENADP--------EKIIEAAKLAG--VHE--LILRLPDGYDTVIGPGGA 453
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  161 ilsryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVAdIADRVL 240
Cdd:TIGR01842 454 -------TLSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKA-RGITVVVITHRPSLLG-CVDKIL 524
                         250
                  ....*....|....*.
gi 949724212  241 VMYQGEAVETGSVEQI 256
Cdd:TIGR01842 525 VLQDGRIARFGERDEV 540
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
27-251 4.75e-17

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 80.65  E-value: 4.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  27 QRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAG------GEVScdemllrrrnrqvielgeqsasqmrh 100
Cdd:cd03220   33 GEFWALKDVSFEVPRGERIGLIGRNGAGKS----TLLRLL--AGiyppdsGTVT-------------------------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 101 VRGADIAMIfqEPMTSLNPVFTVGEQIAESIRLHqGASHEEAmveaKRMLDQVripEAKAILSRYPHQ----LSGGMRQR 176
Cdd:cd03220   81 VRGRVSSLL--GLGGGFNPELTGRENIYLNGRLL-GLSRKEI----DEKIDEI---IEFSELGDFIDLpvktYSSGMKAR 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03220  151 LAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKT-VILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
19-251 5.34e-17

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 80.33  E-value: 5.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIelgeqsasqM 98
Cdd:cd03245    7 NVSFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADL---------R 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RHvrgadIAMIFQEPMtslnpVF--TVGEQIAesirLHQGASHEEAMVEAkrmldqVRIPEAKAILSRYPH--------- 167
Cdd:cd03245   78 RN-----IGYVPQDVT-----LFygTLRDNIT----LGAPLADDERILRA------AELAGVTDFVNKHPNgldlqiger 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 168 --QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgvIFITHDMGVVaDIADRVLVMYQG 245
Cdd:cd03245  138 grGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTL--IIITHRPSLL-DLVDRIIVMDSG 214

                 ....*.
gi 949724212 246 EAVETG 251
Cdd:cd03245  215 RIVADG 220
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
31-251 5.85e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 82.06  E-value: 5.85e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSC---DEMLLRRRNRQVIELGEQ--SASQMRHVRGAD 105
Cdd:PRK13651  22 ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkDEKNKKKTKEKEKVLEKLviQKTRFKKIKKIK 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 -----IAMIFQEPMTSLnpvF--TVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIPEAkaILSRYPHQLSGGMRQRVM 178
Cdd:PRK13651 102 eirrrVGVVFQFAEYQL---FeqTIEKDIIFGPV-SMGVSKEEAKKRAAKYIELVGLDES--YLQRSPFELSGGQKRRVA 175
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 179 IAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:PRK13651 176 LAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNK-QGKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDG 247
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
13-260 6.41e-17

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 83.35  E-value: 6.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrNRQVIELGE 92
Cdd:PRK09536   4 IDVSDLSVEFGD----TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVA-------GDDVEALSA 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMrhvrgadIAMIFQEpmTSLNPVFTVgEQIAE------SIRLHQGASHEEAMVEakRMLDQVripEAKAILSRYP 166
Cdd:PRK09536  73 RAASRR-------VASVPQD--TSLSFEFDV-RQVVEmgrtphRSRFDTWTETDRAAVE--RAMERT---GVAQFADRPV 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFItHDMGVVADIADRVLVMYQGE 246
Cdd:PRK09536 138 TSLSGGERQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAI-HDLDLAARYCDELVLLADGR 216
                        250
                 ....*....|....
gi 949724212 247 AVETGSVEQIFHAP 260
Cdd:PRK09536 217 VRAAGPPADVLTAD 230
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
13-278 6.61e-17

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 80.83  E-value: 6.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQeqQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrnrqviELGE 92
Cdd:PRK11231   3 LRTENLTVGYGT--KRI--LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDK----------PISM 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQM-RHvrgadIAMIFQEPMTSLNpvFTVGEQIA--ESIRL-HQG--ASHEEAMVEakRMLDQVRIPEakaILSRYP 166
Cdd:PRK11231  69 LSSRQLaRR-----LALLPQHHLTPEG--ITVRELVAygRSPWLsLWGrlSAEDNARVN--QAMEQTRINH---LADRRL 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:PRK11231 137 TDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGH 215
                        250       260       270
                 ....*....|....*....|....*....|..
gi 949724212 247 AVETGSVEQIFhapqhpyTKALLAAVPQLGAM 278
Cdd:PRK11231 216 VMAQGTPEEVM-------TPGLLRTVFDVEAE 240
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
314-553 7.12e-17

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 84.08  E-value: 7.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  314 LRVRNLVTRFplrsgilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRaLLRLVESQR---GEIIFN------ 384
Cdd:TIGR03269   1 IEVKNLTKKF-----------DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMH-VLRGMDQYEptsGRIIYHvalcek 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  385 ----------------------GQRIDTLAASK--LQPLRRDIQFIFQDPYAsLDPRQTVGYSILEPLRVHGLlQGDAGS 440
Cdd:TIGR03269  69 cgyverpskvgepcpvcggtlePEEVDFWNLSDklRRRIRKRIAIMLQRTFA-LYGDDTVLDNVLEALEEIGY-EGKEAV 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  441 KRVAWLLERVGLlpEHawRYPH---EFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAY 517
Cdd:TIGR03269 147 GRAVDLIEMVQL--SH--RITHiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISM 222
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 949724212  518 LFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:TIGR03269 223 VLTSHWPEVIEDLSDKAIWLENGEIKEEGTPDEVVA 258
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
336-543 7.39e-17

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 84.39  E-value: 7.39e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRD-IQFIFQDPY--A 412
Cdd:PRK10535  20 QVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQLRREhFGFIFQRYHllS 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 413 SLDPRQTVgysilEPLRVHGLLQGDAGSKRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVS 492
Cdd:PRK10535 100 HLTAAQNV-----EVPAVYAGLERKQRLLRAQELLQRLGL-EDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTG 173
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 949724212 493 ALDvSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQIV 543
Cdd:PRK10535 174 ALD-SHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIV 222
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
31-251 7.56e-17

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 79.57  E-value: 7.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielgeQSASQMRHVRGADIAMIF 110
Cdd:cd03268   15 VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFD----------------GKSYQKNIEALRRIGALI 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPmtSLNPVFTVGEQIAESIRLHqGASHEEAMveakRMLDQVRipeakaiLSRYPH----QLSGGMRQRVMIAMALSCR 186
Cdd:cd03268   79 EAP--GFYPNLTARENLRLLARLL-GIRKKRID----EVLDVVG-------LKDSAKkkvkGFSLGMKQRLGIALALLGN 144
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 187 PAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:cd03268  145 PDLLILDEPTNGLDPDGIKELRELILSL-RDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
31-254 7.57e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 80.94  E-value: 7.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTalsLMHLieqaggevscDEMLLRRRNRQVIELGEQSASQMRHVRGAdIAMIF 110
Cdd:PRK13647  20 ALKGLSLSIPEGSKTALLGPNGAGKSTL---LLHL----------NGIYLPQRGRVKVMGREVNAENEKWVRSK-VGLVF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEPMtslNPVF--TVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK13647  86 QDPD---DQVFssTVWDDVAFGPV-NMGLDKDEVERRVEEALKAVRM---WDFRDKPPYHLSYGQKKRVAIAGVLAMDPD 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 189 VLIADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVADIADRVLVMYQGEAVETGSVE 254
Cdd:PRK13647 159 VIVLDEPMAYLDPRGQETLMEILDRLHNQGKT-VIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS 223
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
32-246 1.03e-16

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 79.44  E-value: 1.03e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLrrrnrqvielgeqSASQMRHVRgADIAMIFQ 111
Cdd:cd03248   30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPI-------------SQYEHKYLH-SKVSLVGQ 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EPMTSLNpvfTVGEQIAESIrlhQGASHEEAMVEAKRMldqvripEAKAILSRYPH-----------QLSGGMRQRVMIA 180
Cdd:cd03248   96 EPVLFAR---SLQDNIAYGL---QSCSFECVKEAAQKA-------HAHSFISELASgydtevgekgsQLSGGQKQRVAIA 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 181 MALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVaDIADRVLVMYQGE 246
Cdd:cd03248  163 RALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRT--VLVIAHRLSTV-ERADQILVLDGGR 225
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
37-256 1.10e-16

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 79.51  E-value: 1.10e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   37 FRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIELGEqsasqmRHVRGADIamifqePMTS 116
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGASPGKGWRHIGYVPQ------RHEFAWDF------PISV 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  117 LNPVFTVGEQIAESIRLHQGASHEeAMVEAkrmLDQVRIPEakaiLSRYP-HQLSGGMRQRVMIAMALSCRPAVLIADEP 195
Cdd:TIGR03771  69 AHTVMSGRTGHIGWLRRPCVADFA-AVRDA---LRRVGLTE----LADRPvGELSGGQRQRVLVARALATRPSVLLLDEP 140
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212  196 TTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVlVMYQGEAVETGSVEQI 256
Cdd:TIGR03771 141 FTGLDMPTQELLTELFIELAGA-GTAILMTTHDLAQAMATCDRV-VLLNGRVIADGTPQQL 199
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
337-550 1.11e-16

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 83.34  E-value: 1.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  337 VHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE--SQRGEIIFNGQRIDtlAASKLQPLRRDIQFIFQDpyASL 414
Cdd:TIGR02633  14 VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgTWDGEIYWSGSPLK--ASNIRDTERAGIVIIHQE--LTL 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  415 DPRQTVGYSIL---EPLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:TIGR02633  90 VPELSVAENIFlgnEITLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEPS 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212  492 SALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQivEIGTRRA 550
Cdd:TIGR02633 170 SSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQ--HVATKDM 225
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
33-261 1.18e-16

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 82.00  E-value: 1.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGGE-VSCDEMLLrrrnrqvielGEQsasQMRHVRGAD--IAMI 109
Cdd:PRK11000  20 KDINLDIHEGEFVVFVGPSGCGKS----TLLRMI--AGLEdITSGDLFI----------GEK---RMNDVPPAErgVGMV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQEpmTSLNPVFTVGEQIAESIRLhqgASHEEAmvEAKRMLDQV-RIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:PRK11000  81 FQS--YALYPHLSVAENMSFGLKL---AGAKKE--EINQRVNQVaEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPS 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 189 VLIADEPTTALD----VTIQAQILQLIKVLQQDMsmgvIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPQ 261
Cdd:PRK11000 154 VFLLDEPLSNLDaalrVQMRIEISRLHKRLGRTM----IYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPA 226
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
313-543 1.76e-16

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 79.74  E-value: 1.76e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFplrsgilNRVT-REVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQR 387
Cdd:COG1101    1 MLELKNLSKTF-------NPGTvNEKRALDGLNLTIEEGDFVTVIGSNGAGKST----LLNAIagslPPDSGSILIDGKD 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 388 IDTLAASKlqplR-RDIQFIFQDPYASLDPRQTvgysILEPL-------RVHGLLQGDAGSKR------VAWL---LE-- 448
Cdd:COG1101   70 VTKLPEYK----RaKYIGRVFQDPMMGTAPSMT----IEENLalayrrgKRRGLRRGLTKKRRelfrelLATLglgLEnr 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 449 ---RVGLLpehawryphefSGGQRQriciarALAL------NPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLF 519
Cdd:COG1101  142 ldtKVGLL-----------SGGQRQ------ALSLlmatltKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLM 204
                        250       260
                 ....*....|....*....|....*.
gi 949724212 520 ISHDM--AVveRISHRVAVMYLGQIV 543
Cdd:COG1101  205 VTHNMeqAL--DYGNRLIMMHEGRII 228
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
33-246 2.31e-16

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 79.34  E-value: 2.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEvscdemLLRrrnrqvielGEQSASQMRHvrgaDIAMIFQ 111
Cdd:PRK11247  29 NQLDLHIPAGQFVAVVGRSGCGKS-TLLRLLAGLETPsAGE------LLA---------GTAPLAEARE----DTRLMFQ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EpmTSLNPVFTVGEQIAESIRLHQGASHEEAMvEAKRMLDqvRIPEakailsrYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:PRK11247  89 D--ARLLPWKKVIDNVGLGLKGQWRDAALQAL-AAVGLAD--RANE-------WPAALSGGQKQRVALARALIHRPGLLL 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGE 246
Cdd:PRK11247 157 LDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
340-552 2.96e-16

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 79.05  E-value: 2.96e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRrdiqfifqdpyASLdPRQT 419
Cdd:PRK13548  18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRR-----------AVL-PQHS 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 vgySILEPLRVH-----GLLQGDAGSKRVAWL----LERVGLLpEHAWRYPHEFSGGQRQRICIARALA------LNPKV 484
Cdd:PRK13548  86 ---SLSFPFTVEevvamGRAPHGLSRAEDDALvaaaLAQVDLA-HLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRW 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 485 IIADESVSALDvsIRGQIINLML--DLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVF 552
Cdd:PRK13548 162 LLLDEPTSALD--LAHQHHVLRLarQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVL 229
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
33-271 4.43e-16

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 81.79  E-value: 4.43e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRrrnrqviELGEQSasqmrhVRGAdIAMIFQE 112
Cdd:COG5265  375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIR-------DVTQAS------LRAA-IGIVPQD 440
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 113 pmTSLnpvF--TVGEQIAESiRLhqGASHEEaMVEAKRM--LDQ--VRIPEA----------KailsryphqLSGGMRQR 176
Cdd:COG5265  441 --TVL---FndTIAYNIAYG-RP--DASEEE-VEAAARAaqIHDfiESLPDGydtrvgerglK---------LSGGEKQR 502
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVETGSveqi 256
Cdd:COG5265  503 VAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVARGRT--TLVIAHRLSTIVD-ADEILVLEAGRIVERGT---- 575
                        250
                 ....*....|....*
gi 949724212 257 fHApqhpytkALLAA 271
Cdd:COG5265  576 -HA-------ELLAQ 582
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
2-246 5.02e-16

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 81.02  E-value: 5.02e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    2 PHSDELDASDVLAVSNLNiAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIE-QAGGEVSCDEMLL 80
Cdd:TIGR02633 247 PHEPHEIGDVILEARNLT-CWDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPgKFEGNVFINGKPV 325
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   81 RRRN-RQVIELGeqsasqmrhvrgadIAMIFQE-PMTSLNPVFTVGEQIA-ESIRLHQGASHEEAMVEAKRMLDQVRIPE 157
Cdd:TIGR02633 326 DIRNpAQAIRAG--------------IAMVPEDrKRHGIVPILGVGKNITlSVLKSFCFKMRIDAAAELQIIGSAIQRLK 391
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  158 AKAILSRYP-HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIA 236
Cdd:TIGR02633 392 VKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLS 470
                         250
                  ....*....|
gi 949724212  237 DRVLVMYQGE 246
Cdd:TIGR02633 471 DRVLVIGEGK 480
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
10-261 5.48e-16

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 77.71  E-value: 5.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCD-EMLLRRRNRQVI 88
Cdd:COG0410    1 MPMLEVENLHAGYGG----IHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDgEDITGLPPHRIA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELGeqsasqMRHV---RGadiamIFQEpMTslnpvftvgeqIAESIRLhqGASHEEAMVEAKRMLDQV--RIPEAKAILS 163
Cdd:COG0410   77 RLG------IGYVpegRR-----IFPS-LT-----------VEENLLL--GAYARRDRAEVRADLERVyeLFPRLKERRR 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 164 RYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMY 243
Cdd:COG0410  132 QRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRL-NREGVTILLVEQNARFALEIADRAYVLE 210
                        250
                 ....*....|....*...
gi 949724212 244 QGEAVETGSVEQIFHAPQ 261
Cdd:COG0410  211 RGRIVLEGTAAELLADPE 228
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
12-267 6.18e-16

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 78.29  E-value: 6.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSvTALS----LMHLIE--QAGGEV----------SC 75
Cdd:PRK14243  10 VLRTENLNVYYGSFL----AVKNVWLDIPKNQITAFIGPSGCGKS-TILRcfnrLNDLIPgfRVEGKVtfhgknlyapDV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  76 DEMLLRRRnrqvielgeqsasqmrhvrgadIAMIFQEPmtslNPvF--TVGEQIAESIRLHQGASHEEAMVEakRMLDQV 153
Cdd:PRK14243  85 DPVEVRRR----------------------IGMVFQKP----NP-FpkSIYDNIAYGARINGYKGDMDELVE--RSLRQA 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 154 RI-PEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVV 232
Cdd:PRK14243 136 ALwDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYT--IIIVTHNMQQA 213
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 949724212 233 ADIADRVLVM---------YQGEAVETGSVEQIFHAPQHPYTKA 267
Cdd:PRK14243 214 ARVSDMTAFFnveltegggRYGYLVEFDRTEKIFNSPQQQATRD 257
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
13-260 6.57e-16

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 77.72  E-value: 6.57e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQeqqrVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrQVIE-LG 91
Cdd:PRK11300   6 LSVSGLMMRFGG----LLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRG--------QHIEgLP 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRGADIAMIFQEpMTSLNPVFtvgeqIAESIRLHQG------------ASHEEAMVEAKRMLDQVRIpeaK 159
Cdd:PRK11300  74 GHQIARMGVVRTFQHVRLFRE-MTVIENLL-----VAQHQQLKTGlfsgllktpafrRAESEALDRAATWLERVGL---L 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 160 AILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRV 239
Cdd:PRK11300 145 EHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRI 224
                        250       260
                 ....*....|....*....|.
gi 949724212 240 LVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK11300 225 YVVNQGTPLANGTPEEIRNNP 245
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
19-252 6.67e-16

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 81.22  E-value: 6.67e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLrrRNRQVIELGEQSA--S 96
Cdd:PRK11176 346 NVTFTYPGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDL--RDYTLASLRNQVAlvS 423
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  97 QMRHVRGADIAMifqepmtslNPVFTVGEQIA-ESIRLHQGASHeeAMVEAKRM---LDQVrIPEAKAIlsryphqLSGG 172
Cdd:PRK11176 424 QNVHLFNDTIAN---------NIAYARTEQYSrEQIEEAARMAY--AMDFINKMdngLDTV-IGENGVL-------LSGG 484
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVETGS 252
Cdd:PRK11176 485 QRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRT--SLVIAHRLSTIEK-ADEILVVEDGEIVERGT 561
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
311-556 8.32e-16

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 77.38  E-value: 8.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvTREVhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDT 390
Cdd:COG1137    1 MMTLEAENLVKSYG---------KRTV--VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITH 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 LaasklqPL----RRDIQFIFQDPyaSLDPRQTVGYSILEPLRVHGLlQGDAGSKRVAWLLERVGLlpEH-AWRYPHEFS 465
Cdd:COG1137   70 L------PMhkraRLGIGYLPQEA--SIFRKLTVEDNILAVLELRKL-SKKEREERLEELLEEFGI--THlRKSKAYSLS 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 466 GGQRQRICIARALALNPKVIIADESVSALD---VS-IRGQIINLmldlqRELGIAYLFISHDmaVVE--RISHRVAVMYL 539
Cdd:COG1137  139 GGERRRVEIARALATNPKFILLDEPFAGVDpiaVAdIQKIIRHL-----KERGIGVLITDHN--VREtlGICDRAYIISE 211
                        250
                 ....*....|....*..
gi 949724212 540 GQIVEIGTRRAVFENPQ 556
Cdd:COG1137  212 GKVLAEGTPEEILNNPL 228
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
314-553 9.68e-16

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 80.56  E-value: 9.68e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAA 393
Cdd:COG4618  331 LSVENLTVVPP---------GSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDR 401
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 SKLQP----LRRDIQFI----------FQDPyaslDPRQtvgysILEPLR---VHGLLQ----------GDAGSkrvawl 446
Cdd:COG4618  402 EELGRhigyLPQDVELFdgtiaeniarFGDA----DPEK-----VVAAAKlagVHEMILrlpdgydtriGEGGA------ 466
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 447 lervGLlpehawryphefSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAV 526
Cdd:COG4618  467 ----RL------------SGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRAL-KARGATVVVITHRPSL 529
                        250       260
                 ....*....|....*....|....*..
gi 949724212 527 VeRISHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:COG4618  530 L-AAVDKLLVLRDGRVQAFGPRDEVLA 555
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
32-257 1.14e-15

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 76.81  E-value: 1.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEvscdemllrrrnrqvIELGEQSASQMRHVRGADIAMIF- 110
Cdd:cd03218   16 VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGK---------------ILLDGQDITKLPMHKRARLGIGYl 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 -QEPmtSLNPVFTVGEQIAESIRLHqGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSCRPAV 189
Cdd:cd03218   81 pQEA--SIFRKLTVEENILAVLEIR-GLSKKEREEKLEELLEEFHI---THLRKSKASSLSGGERRRVEIARALATNPKF 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 190 LIADEPTTALDVTIQAQILQLIKVLqQDMSMGvIFIT-HDMGVVADIADRVLVMYQGEAVETGSVEQIF 257
Cdd:cd03218  155 LLLDEPFAGVDPIAVQDIQKIIKIL-KDRGIG-VLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
8-255 1.50e-15

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 80.09  E-value: 1.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    8 DASDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEqAGGEVSCDEMLlrrrNRQV 87
Cdd:TIGR00955  17 DGSWKQLVSRLRGCFCRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSP-KGVKGSGSVLL----NGMP 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   88 IElgeqsASQMRHVRgadiAMIFQEPMtsLNPVFTVGEQIAES--IRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRY 165
Cdd:TIGR00955  92 ID-----AKEMRAIS----AYVQQDDL--FIPTLTVREHLMFQahLRMPRRVTKKEKRERVDEVLQALGLRKCANTRIGV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  166 PHQ---LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVM 242
Cdd:TIGR00955 161 PGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILM 240
                         250
                  ....*....|...
gi 949724212  243 YQGEAVETGSVEQ 255
Cdd:TIGR00955 241 AEGRVAYLGSPDQ 253
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
342-547 1.59e-15

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 79.86  E-value: 1.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasKLQPLRRDIQFIFQDPYASLDprqTVG 421
Cdd:COG5265  376 GVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDV---TQASLRAAIGIVPQDTVLFND---TIA 449
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 422 YSIleplrvhglLQGDAGSK--------RVAWLLERVGLLPEhawRYPHE-------FSGGQRQRICIARALALNPKVII 486
Cdd:COG5265  450 YNI---------AYGRPDASeeeveaaaRAAQIHDFIESLPD---GYDTRvgerglkLSGGEKQRVAIARTLLKNPPILI 517
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 487 ADESVSALDVSIRGQIinlmldlQRELGIA-----YLFISHdmavveRIS-----HRVAVMYLGQIVEIGT 547
Cdd:COG5265  518 FDEATSALDSRTERAI-------QAALREVargrtTLVIAH------RLStivdaDEILVLEAGRIVERGT 575
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
13-248 1.91e-15

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 79.77  E-value: 1.91e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEvscdemlLRRRNRQVIELGE 92
Cdd:PRK10535   5 LELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGT-------YRVAGQDVATLDA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHvrgADIAMIFQEpmTSLNPVFTvGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAkaiLSRYPHQLSGG 172
Cdd:PRK10535  78 DALAQLRR---EHFGFIFQR--YHLLSHLT-AAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDR---VEYQPSQLSGG 148
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADiADRVLVMYQGEAV 248
Cdd:PRK10535 149 QQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQL-RDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIV 222
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
13-248 2.14e-15

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 76.66  E-value: 2.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQR-VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGGEVSCDEmllrrrnrQVIELG 91
Cdd:COG1101    2 LELKNLSKTFNPGTVNeKRALDGLNLTIEEGDFVTVIGSNGAGKS----TLLNAI---AGSLPPDS--------GSILID 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMR-HVRGADIAMIFQEPMTSLNPVFTVGEQIA------ESIRLHQGASHEE-----AMVEA------KRMLDQV 153
Cdd:COG1101   67 GKDVTKLPeYKRAKYIGRVFQDPMMGTAPSMTIEENLAlayrrgKRRGLRRGLTKKRrelfrELLATlglgleNRLDTKV 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 154 RipeakailsryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVA 233
Cdd:COG1101  147 G-------------LLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQAL 213
                        250
                 ....*....|....*
gi 949724212 234 DIADRVLVMYQGEAV 248
Cdd:COG1101  214 DYGNRLIMMHEGRII 228
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
340-553 2.32e-15

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 77.15  E-value: 2.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKlqplRRDIQFIFQdpYASLDPrqt 419
Cdd:PRK13537  23 VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHA----RQRVGVVPQ--FDNLDP--- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 vGYSILEPLRVHGL---LQGDAGSKRVAWLLErVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:PRK13537  94 -DFTVRENLLVFGRyfgLSAAAARALVPPLLE-FAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDP 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 497 SIRgqiiNLMLDLQREL---GIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:PRK13537 172 QAR----HLMWERLRSLlarGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIE 227
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
357-559 6.38e-15

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 76.45  E-value: 6.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 357 GESGCGKSTTGRALLRLVESQRGEIIFNGQR-IDTLAASKLQPLRRDIQFIFQDpyASLDPRqtvgYsileplRVHGLLQ 435
Cdd:PRK11144  31 GRSGAGKTSLINAISGLTRPQKGRIVLNGRVlFDAEKGICLPPEKRRIGYVFQD--ARLFPH----Y------KVRGNLR 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 436 GDAGSKRVAWLLERVGLLP-EHAW-RYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQREL 513
Cdd:PRK11144  99 YGMAKSMVAQFDKIVALLGiEPLLdRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREI 178
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 949724212 514 GIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ-HPY 559
Cdd:PRK11144 179 NIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSAmRPW 225
cbiO PRK13649
energy-coupling factor transporter ATPase;
336-553 6.54e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 75.55  E-value: 6.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASK-LQPLRRDIQFIFQDPYASL 414
Cdd:PRK13649  19 EGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKdIKQIRKKVGLVFQFPESQL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DpRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK13649  99 F-EETVLKDVAFGPQNFGVSQEEA-EALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGL 176
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 495 DVSIRGQIINLMLDLQrELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFE 553
Cdd:PRK13649 177 DPKGRKELMTLFKKLH-QSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQ 234
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
328-543 7.50e-15

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 74.29  E-value: 7.50e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 328 GILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGqridtLAASKLQP-LRRDIQFI 406
Cdd:cd03267   25 SLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG-----LVPWKRRKkFLRRIGVV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 407 F---QDPYASLDPRQtvGYSILEplRVHGLLQGDAGsKRVAWLLERVGLlpEHAWRYP-HEFSGGQRQRICIARALALNP 482
Cdd:cd03267  100 FgqkTQLWWDLPVID--SFYLLA--AIYDLPPARFK-KRLDELSELLDL--EELLDTPvRQLSLGQRMRAEIAAALLHEP 172
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 483 KVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
Cdd:cd03267  173 EILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
314-601 8.18e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 75.51  E-value: 8.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFPLRSGIlnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEI--IFNGQRIDTL 391
Cdd:PRK13651   3 IKVKNIVKIFNKKLPT------ELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDEKNKKK 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AAS-------------------KLQPLRRDIQFIFQdpYASLDP-RQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVG 451
Cdd:PRK13651  77 TKEkekvleklviqktrfkkikKIKEIRRRVGVVFQ--FAEYQLfEQTIEKDIIFGPVSMGVSKEEA-KKRAAKYIELVG 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 452 LLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERIS 531
Cdd:PRK13651 154 LDESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLEWT 232
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 532 HRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMaavpvadpshhrPQRVLlsdDIPSNIRKRGEEISPVS 601
Cdd:PRK13651 233 KRTIFFKDGKIIKDGDTYDILSDNKFLIENNME------------PPKLL---NFVNKLEKKGIDVPKVT 287
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
340-522 9.96e-15

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 77.15  E-value: 9.96e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFngqridtlaasklqPLRRDIQFIFQDPY---ASLdp 416
Cdd:COG4178  379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR--------------PAGARVLFLPQRPYlplGTL-- 442
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYsilePLRVHgllqgDAGSKRVAWLLERVGL--LPEH-----AWryPHEFSGGQRQRICIARALALNPKVIIADE 489
Cdd:COG4178  443 REALLY----PATAE-----AFSDAELREALEAVGLghLAERldeeaDW--DQVLSLGEQQRLAFARLLLHKPDWLFLDE 511
                        170       180       190
                 ....*....|....*....|....*....|....
gi 949724212 490 SVSALDVSIRGQIINLmldLQREL-GIAYLFISH 522
Cdd:COG4178  512 ATSALDEENEAALYQL---LREELpGTTVISVGH 542
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
340-551 1.01e-14

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 77.39  E-value: 1.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQP----LRRDIQFI--------- 406
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKhigyLPQDVELFpgtvaenia 413
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  407 -FQDpyaSLDPRQTVGYSILEplRVHGLLQ----------GDAGSkrvawllervGLlpehawryphefSGGQRQRICIA 475
Cdd:TIGR01842 414 rFGE---NADPEKIIEAAKLA--GVHELILrlpdgydtviGPGGA----------TL------------SGGQRQRIALA 466
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212  476 RALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERIShRVAVMYLGQIVEIGTRRAV 551
Cdd:TIGR01842 467 RALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKAR-GITVVVITHRPSLLGCVD-KILVLQDGRIARFGERDEV 540
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
13-251 1.03e-14

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 72.35  E-value: 1.03e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQA----GGEVSCDEMLlrrrnrqVI 88
Cdd:cd03247    1 LSINNVSFSYPEQEQQV--LKNLSLELKQGEKIALLGRSGSGKS----TLLQLLTGDlkpqQGEITLDGVP-------VS 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELGEQSASQmrhvrgadIAMIFQEPMtslnpVFtvgeqiAESIRLHQGAsheeamveakrmldqvripeakailsryphQ 168
Cdd:cd03247   68 DLEKALSSL--------ISVLNQRPY-----LF------DTTLRNNLGR------------------------------R 98
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAV 248
Cdd:cd03247   99 FSGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEVLKDKT--LIWITHHLTGIEH-MDKILFLENGKII 175

                 ...
gi 949724212 249 ETG 251
Cdd:cd03247  176 MQG 178
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
32-256 1.15e-14

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 73.96  E-value: 1.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSvTALSLM-HLIEQAGGEVSCDEMLLRRrnrqvielgeqsasqmrhVRGADIAMIF 110
Cdd:COG4604   17 LDDVSLTIPKGGITALIGPNGAGKS-TLLSMIsRLLPPDSGEVLVDGLDVAT------------------TPSRELAKRL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 ----QEPmtSLNPVFTVGEqiaesirL--------HQGASHEEamveakrmlDQVRIPEAKAILS------RYPHQLSGG 172
Cdd:COG4604   78 ailrQEN--HINSRLTVRE-------LvafgrfpySKGRLTAE---------DREIIDEAIAYLDledladRYLDELSGG 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 173 MRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGS 252
Cdd:COG4604  140 QRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGT 219

                 ....
gi 949724212 253 VEQI 256
Cdd:COG4604  220 PEEI 223
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
313-547 1.50e-14

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 73.58  E-value: 1.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRSGILNRV-----------TREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEI 381
Cdd:COG1134    4 MIEVENVSKSYRLYHEPSRSLkelllrrrrtrREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 382 IFNGqridtlaasklqplrrdiqfifqdpyasldprqtvgysileplrvhgllqgdagskRVAWLLE-RVGLLPEH---- 456
Cdd:COG1134   84 EVNG--------------------------------------------------------RVSALLElGAGFHPELtgre 107
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 457 ----------------AWRYPH--EFSG--------------GQRQRICIARALALNPKVIIADESVSALDVSIRGQIIN 504
Cdd:COG1134  108 niylngrllglsrkeiDEKFDEivEFAElgdfidqpvktyssGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLA 187
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 949724212 505 LMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:COG1134  188 RIRELRES-GRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGD 229
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
313-543 1.65e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 74.74  E-value: 1.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPLRS----------GILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEII 382
Cdd:COG4586    1 IIEVENLSKTYRVYEkepglkgalkGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 383 FNG-----QRIDtlaasklqpLRRDIQFIF-QdpyasldpRQTVGY--SILEPLRVHGLLQG---DAGSKRVAWLLERVG 451
Cdd:COG4586   81 VLGyvpfkRRKE---------FARRIGVVFgQ--------RSQLWWdlPAIDSFRLLKAIYRipdAEYKKRLDELVELLD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 452 LlpEHAWRYP-HEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERI 530
Cdd:COG4586  144 L--GELLDTPvRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEAL 221
                        250
                 ....*....|...
gi 949724212 531 SHRVAVMYLGQIV 543
Cdd:COG4586  222 CDRVIVIDHGRII 234
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
342-546 1.72e-14

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 73.07  E-value: 1.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ---RGEIIFNGQridtlaASKLQPLRRDIQFIFQDPY--ASLDP 416
Cdd:cd03234   25 DVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQ------PRKPDQFQKCVAYVRQDDIllPGLTV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYSIlePLRVHGLLQGDAGSKRVA-WLLERVGLLPEHAWRYPHeFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:cd03234   99 RETLTYTA--ILRLPRKSSDAIRKKRVEdVLLRDLALTRIGGNLVKG-ISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 949724212 496 VSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03234  176 SFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
340-556 2.44e-14

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 73.00  E-value: 2.44e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasklqPL----RRDIQFIFQDpyASLD 415
Cdd:PRK10895  19 VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLL------PLharaRRGIGYLPQE--ASIF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILEPLRVHGLLQGDAGSKRVAWLLERVGLlpEHAW-RYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK10895  91 RRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHI--EHLRdSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGV 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 495 DvSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK10895 169 D-PISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEH 229
GguA NF040905
sugar ABC transporter ATP-binding protein;
313-544 2.70e-14

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 75.60  E-value: 2.70e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 313 ILRVRNLVTRFPlrsGilnrvtreVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLVE------SQRGEIIFNGQ 386
Cdd:NF040905   1 ILEMRGITKTFP---G--------VKALDDVNLSVREGEIHALCGENGAGKST----LMKVLSgvyphgSYEGEILFDGE 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 --RIDTLAASKlqplRRDIQFIFQDpyASLDPRQTVGYSIL---EPLRvHGLLQGDAGSKRVAWLLERVGlLPEHawryP 461
Cdd:NF040905  66 vcRFKDIRDSE----ALGIVIIHQE--LALIPYLSIAENIFlgnERAK-RGVIDWNETNRRARELLAKVG-LDES----P 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 HEFSG----GQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVM 537
Cdd:NF040905 134 DTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVL 212

                 ....*..
gi 949724212 538 YLGQIVE 544
Cdd:NF040905 213 RDGRTIE 219
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
159-264 3.53e-14

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 74.14  E-value: 3.53e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 159 KAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADR 238
Cdd:PRK11144 119 EPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADR 198
                         90       100
                 ....*....|....*....|....*..
gi 949724212 239 VLVMYQGEAVETGSVEQIFHAPQ-HPY 264
Cdd:PRK11144 199 VVVLEQGKVKAFGPLEEVWASSAmRPW 225
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
29-251 3.60e-14

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 72.30  E-value: 3.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAG---GEVSCDEMLLRRrnrqvielgEQSASQMRHVRGAD 105
Cdd:cd03234   20 ARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPRKP---------DQFQKCVAYVRQDD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 IamifqepmtsLNPVFTVGEQIAESIRLhqgASHEEAMVEAKRMLDQVRIPEAKAILS---RYPHQLSGGMRQRVMIAMA 182
Cdd:cd03234   91 I----------LLPGLTVRETLTYTAIL---RLPRKSSDAIRKKRVEDVLLRDLALTRiggNLVKGISGGERRRVSIAVQ 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 183 LSCRPAVLIADEPTTALDVTIQaqiLQLIKVLQQDMSMGVIFIT--HDMGV-VADIADRVLVMYQGEAVETG 251
Cdd:cd03234  158 LLWDPKVLILDEPTSGLDSFTA---LNLVSTLSQLARRNRIVILtiHQPRSdLFRLFDRILLLSSGEIVYSG 226
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
35-256 5.62e-14

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 71.89  E-value: 5.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  35 LSFRLKRGETLAIVGESGSGKSvTALSLMHLIEQAGGEVSCDEMLLRrrnrqvielgEQSASQMRHVRGAdiaMIFQEPM 114
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKS-TLLARMAGLLPGSGSIQFAGQPLE----------AWSAAELARHRAY---LSQQQTP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 115 TSLNPVFtvgeqiaESIRLHQGASHEEAMVEA--KRMLDQVRIPEAkaiLSRYPHQLSGGMRQRVMIAMA-LSCRPAV-- 189
Cdd:PRK03695  81 PFAMPVF-------QYLTLHQPDKTRTEAVASalNEVAEALGLDDK---LGRSVNQLSGGEWQRVRLAAVvLQVWPDInp 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 190 ----LIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:PRK03695 151 agqlLLLDEPMNSLDVAQQAALDRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEV 220
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
31-242 6.16e-14

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 70.73  E-value: 6.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemLLRrrnrqvielgeQSASQMRHVRGADIAMIF 110
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKS----TLLKVL--AG--------VLR-----------PTSGTVRRAGGARVAYVP 61
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 111 QEpmTSLNPVF--TVGEQIAESIRLHQGAS-----HEEAMVEakRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMAL 183
Cdd:NF040873  62 QR--SEVPDSLplTVRDLVAMGRWARRGLWrrltrDDRAAVD--DALERVGL---ADLAGRQLGELSGGQRQRALLAQGL 134
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADiADRVLVM 242
Cdd:NF040873 135 AQEADLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRR-ADPCVLL 191
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
323-505 8.65e-14

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 74.36  E-value: 8.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 323 FPLRSGILNRVTREVH-------AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLaasK 395
Cdd:PRK10789 307 VPEGRGELDVNIRQFTypqtdhpALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKL---Q 383
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 396 LQPLRRDIQFIFQDPYASLDprqTVGYSIleplrvhGLLQGDAGSK------RVAWLLERVGLLPEHawrYPHE------ 463
Cdd:PRK10789 384 LDSWRSRLAVVSQTPFLFSD---TVANNI-------ALGRPDATQQeiehvaRLASVHDDILRLPQG---YDTEvgergv 450
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 949724212 464 -FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQII-NL 505
Cdd:PRK10789 451 mLSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILhNL 494
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
19-261 8.87e-14

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 71.46  E-value: 8.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDE-----MLLRRRNRQVIELGEQ 93
Cdd:PRK10895   8 NLAKAYKGRRV--VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDedislLPLHARARRGIGYLPQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  94 SASQMRHVrgadiamifqepmtslnpvfTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRyphQLSGGM 173
Cdd:PRK10895  86 EASIFRRL--------------------SVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQ---SLSGGE 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 174 RQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSV 253
Cdd:PRK10895 143 RRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTP 221

                 ....*...
gi 949724212 254 EQIFHAPQ 261
Cdd:PRK10895 222 TEILQDEH 229
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
340-546 1.10e-13

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 70.25  E-value: 1.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRL--VESQRGEIIFNGQriDTLAASKLQPLRRDIQFIFQdpyasldpr 417
Cdd:cd03217   16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGE--DITDLPPEERARLGIFLAFQ--------- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 qtvgysilEPLRVHGLlqgdagskRVAWLLervgllpehawRYPHE-FSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:cd03217   85 --------YPPEIPGV--------KNADFL-----------RYVNEgFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDI 137
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 949724212 497 -SIR--GQIINLMldlqRELGIAYLFISHDMAVVERI-SHRVAVMYLGQIVEIG 546
Cdd:cd03217  138 dALRlvAEVINKL----REEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSG 187
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
6-255 1.19e-13

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 73.69  E-value: 1.19e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   6 ELDASDVLAVSNLNIAFEQEQQRVsavRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAG------GEVSCDEml 79
Cdd:COG4178  356 ETSEDGALALEDLTLRTPDGRPLL---EDLSLSLKPGERLLITGPSGSGKS----TLLRAI--AGlwpygsGRIARPA-- 424
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  80 lrrrnrqvielgeqsasqmrhvrGADIAMIFQEPMTslnPVFTVGEQIAesiRLHQGASHEEAmvEAKRMLDQVRIPEAK 159
Cdd:COG4178  425 -----------------------GARVLFLPQRPYL---PLGTLREALL---YPATAEAFSDA--ELREALEAVGLGHLA 473
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 160 AILS---RYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKvlQQDMSMGVIFITHDmGVVADIA 236
Cdd:COG4178  474 ERLDeeaDWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLR--EELPGTTVISVGHR-STLAAFH 550
                        250
                 ....*....|....*....
gi 949724212 237 DRVLVMYQGEAVETGSVEQ 255
Cdd:COG4178  551 DRVLELTGDGSWQLLPAEA 569
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
35-260 1.37e-13

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 71.36  E-value: 1.37e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  35 LSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRN-----RQVIELGEQ--SASQMrhvrgadia 107
Cdd:PRK10575  30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSskafaRKVAYLPQQlpAAEGM--------- 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 mifqepmtslnpvfTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRP 187
Cdd:PRK10575 101 --------------TVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDS 166
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 188 AVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK10575 167 RCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGE 239
PLN03232 PLN03232
ABC transporter C family member; Provisional
343-568 1.54e-13

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 74.24  E-value: 1.54e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  343 VSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQPLRRDIQFIFQDPYASldpRQTVGY 422
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDV---AKFGLTDLRRVLSIIPQSPVLF---SGTVRF 1328
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  423 SIlEPLRVHGllqgDAGskrvAW-LLERVGL----------LPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:PLN03232 1329 NI-DPFSEHN----DAD----LWeALERAHIkdvidrnpfgLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEAT 1399
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212  492 SALDVSIRGQIINLMLDLQRELGIayLFISHDMAVVERIShRVAVMYLGQIVEIGTRRAVFENPQHPYTRKLMAAVP 568
Cdd:PLN03232 1400 ASVDVRTDSLIQRTIREEFKSCTM--LVIAHRLNTIIDCD-KILVLSSGQVLEYDSPQELLSRDTSAFFRMVHSTGP 1473
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
30-259 1.62e-13

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 71.07  E-value: 1.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  30 SAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQVIelgeqsasqmrhvrgadIAMI 109
Cdd:PRK15056  21 TALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNL-----------------VAYV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 110 FQ-EPMTSLNPVFTvgEQIAESIR------LHQGASHEEAMVEAKrmLDQVRIPEAKailSRYPHQLSGGMRQRVMIAMA 182
Cdd:PRK15056  84 PQsEEVDWSFPVLV--EDVVMMGRyghmgwLRRAKKRDRQIVTAA--LARVDMVEFR---HRQIGELSGGQKKRVFLARA 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 183 LSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVlVMYQGEAVETGSVEQIFHA 259
Cdd:PRK15056 157 IAQQGQVILLDEPFTGVDVKTEARIISLLREL-RDEGKTMLVSTHNLGSVTEFCDYT-VMVKGTVLASGPTETTFTA 231
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
311-544 1.83e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 73.02  E-value: 1.83e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRI-- 388
Cdd:PRK11288   2 SPYLSFDGIGKTFP-----------GVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMrf 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 389 -DTLAAsklqpLRRDIQFIFQDpyASLDPRQTVGYSILE---PLRvHGLLQGDAGSKRVAWLLERVGLL--PEHAWRYph 462
Cdd:PRK11288  71 aSTTAA-----LAAGVAIIYQE--LHLVPEMTVAENLYLgqlPHK-GGIVNRRLLNYEAREQLEHLGVDidPDTPLKY-- 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 463 eFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQI 542
Cdd:PRK11288 141 -LSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRY 218

                 ..
gi 949724212 543 VE 544
Cdd:PRK11288 219 VA 220
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
342-527 2.06e-13

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 70.53  E-value: 2.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridtlaasklqpLRrdIQFIFQDPYasLDPRQtvg 421
Cdd:PRK09544  22 DVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGK------------LR--IGYVPQKLY--LDTTL--- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 422 ysilePLRVHGLLQGDAGSKRVAWL--LERVGllPEHAWRYP-HEFSGGQRQRICIARALALNPKVIIADESVSALDVSI 498
Cdd:PRK09544  83 -----PLTVNRFLRLRPGTKKEDILpaLKRVQ--AGHLIDAPmQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNG 155
                        170       180
                 ....*....|....*....|....*....
gi 949724212 499 RGQIINLMLDLQRELGIAYLFISHDMAVV 527
Cdd:PRK09544 156 QVALYDLIDQLRRELDCAVLMVSHDLHLV 184
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
34-528 2.08e-13

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 73.06  E-value: 2.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGGEVSCDEMLLRRRNRQVIELGEQSASqmRHVRGAdiamifqep 113
Cdd:PRK11147  21 NAELHIEDNERVCLVGRNGAGKS----TLMKIL---NGEVLLDDGRIIYEQDLIVARLQQDPP--RNVEGT--------- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 114 mtslnpVFT-----VGEQiAESIRLHQGASHEEAMVEAKRMLDQV-----------------RIPEAKAILSRYPHQ--- 168
Cdd:PRK11147  83 ------VYDfvaegIEEQ-AEYLKRYHDISHLVETDPSEKNLNELaklqeqldhhnlwqlenRINEVLAQLGLDPDAals 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 -LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKvlqqDMSMGVIFITHDMGVVADIADR-------VL 240
Cdd:PRK11147 156 sLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLK----TFQGSIIFISHDRSFIRNMATRivdldrgKL 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 241 VMYQGEavetgsveqifhapqhpYTKALLAAVPQL--GAMNGHELPRRFplislhdpshvePQTE---------QDTVVE 309
Cdd:PRK11147 232 VSYPGN-----------------YDQYLLEKEEALrvEELQNAEFDRKL------------AQEEvwirqgikaRRTRNE 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 310 GepilRVRNLVTRFPLRSGILNRV----------TRE---VHAVENVSFDLwPGETL--------------SLVGESGCG 362
Cdd:PRK11147 283 G----RVRALKALRRERSERREVMgtakmqveeaSRSgkiVFEMENVNYQI-DGKQLvkdfsaqvqrgdkiALIGPNGCG 357
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 363 KSTTGRALLRLVESQRGEIifngqRIDTlaasKLqplrrDIQFIfqDPY-ASLDPRQTVGYSILEplrvhgllqgdaGSK 441
Cdd:PRK11147 358 KTTLLKLMLGQLQADSGRI-----HCGT----KL-----EVAYF--DQHrAELDPEKTVMDNLAE------------GKQ 409
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 442 RVAwllerVGLLPEHAWRYPHEF--------------SGGQRQRICIARaLALNP-KVIIADESVSALDVSirgqiinlM 506
Cdd:PRK11147 410 EVM-----VNGRPRHVLGYLQDFlfhpkramtpvkalSGGERNRLLLAR-LFLKPsNLLILDEPTNDLDVE--------T 475
                        570       580
                 ....*....|....*....|....*.
gi 949724212 507 LDLQRELGIAY----LFISHDMAVVE 528
Cdd:PRK11147 476 LELLEELLDSYqgtvLLVSHDRQFVD 501
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
12-246 2.16e-13

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 69.12  E-value: 2.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVSA--VRNLSFRLKRGETLAIVGESGSGKSvtalSLMH-LIEQAGGEVSCDEMLLRRRNRQVI 88
Cdd:cd03213    3 TLSFRNLTVTVKSSPSKSGKqlLKNVSGKAKPGELTAIMGPSGAGKS----TLLNaLAGRRTGLGVSGEVLINGRPLDKR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELGEQSASQMRHvrgaDIAMifqepmtslnPVFTVgeqiaesirlhqgashEEAMVEAKRMldqvripeakailsrypHQ 168
Cdd:cd03213   79 SFRKIIGYVPQD----DILH----------PTLTV----------------RETLMFAAKL-----------------RG 111
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDM-GVVADIADRVLVMYQGE 246
Cdd:cd03213  112 LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLAD-TGRTIICSIHQPsSEIFELFDKLLLLSQGR 189
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
303-547 2.61e-13

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 72.94  E-value: 2.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 303 EQDTVVEGEPILRVRNLVTRFPlrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEII 382
Cdd:PRK11160 328 TTSTAAADQVSLTLNNVSFTYP---------DQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEIL 398
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 383 FNGQRIDTLAASKlqpLRRDIQFIFQDPY---ASL------------DPRQTVgysILEPLRVHGLLQGDAGSKrvAWLL 447
Cdd:PRK11160 399 LNGQPIADYSEAA---LRQAISVVSQRVHlfsATLrdnlllaapnasDEALIE---VLQQVGLEKLLEDDKGLN--AWLG 470
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 448 E--RvgllpehawryphEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHDMA 525
Cdd:PRK11160 471 EggR-------------QLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITHRLT 535
                        250       260
                 ....*....|....*....|..
gi 949724212 526 VVERIShRVAVMYLGQIVEIGT 547
Cdd:PRK11160 536 GLEQFD-RICVMDNGQIIEQGT 556
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
330-528 3.45e-13

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 69.22  E-value: 3.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 330 LNRVTRevHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridtlaasklqplrrDIQFifqd 409
Cdd:COG2401   38 LRVVER--YVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVDVP---------------DNQF---- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 410 pyasldPRQTvgySILEPLrvhgLLQGDAgsKRVAWLLERVGLLPEHAW-RYPHEFSGGQRQRICIARALALNPKVIIAD 488
Cdd:COG2401   97 ------GREA---SLIDAI----GRKGDF--KDAVELLNAVGLSDAVLWlRRFKELSTGQKFRFRLALLLAERPKLLVID 161
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 949724212 489 ESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVE 528
Cdd:COG2401  162 EFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVID 201
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
33-259 3.97e-13

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 70.02  E-value: 3.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRGADIAMIFQE 112
Cdd:PRK10253  24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLD--------------GEHIQHYASKEVARRIGLLAQN 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 113 PMTSLNpvFTVGEQIAESIRLHQG------ASHEEAMVEAKRMLDQVRIPEAKAilsrypHQLSGGMRQRVMIAMALSCR 186
Cdd:PRK10253  90 ATTPGD--ITVQELVARGRYPHQPlftrwrKEDEEAVTKAMQATGITHLADQSV------DTLSGGQRQRAWIAMVLAQE 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 187 PAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHA 259
Cdd:PRK10253 162 TAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTA 234
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
6-251 4.44e-13

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 70.63  E-value: 4.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   6 ELDASDVLAVSNLNIAF---EQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCdemllrr 82
Cdd:PRK13536  28 EAKASIPGSMSTVAIDLagvSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITV------- 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  83 rnrqvieLGEQSASQMRHVRgADIAMIFQepMTSLNPVFTVGEQIAESIRLHQGASHE-EAMVEAkrMLDQVRIpEAKAi 161
Cdd:PRK13536 101 -------LGVPVPARARLAR-ARIGVVPQ--FDNLDLEFTVRENLLVFGRYFGMSTREiEAVIPS--LLEFARL-ESKA- 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 162 lSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdMSMGVIFITHDMGVVADIADRVLV 241
Cdd:PRK13536 167 -DARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLA-RGKTILLTTHFMEEAERLCDRLCV 244
                        250
                 ....*....|
gi 949724212 242 MYQGEAVETG 251
Cdd:PRK13536 245 LEAGRKIAEG 254
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
314-495 5.18e-13

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 67.96  E-value: 5.18e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLvtRFPLRSGILNRVTREVHaveNVSFDLWPGETLSLVGESGCGKSTTGRAL--LRLVESQRGEIIFNGQRIDtl 391
Cdd:cd03213    4 LSFRNL--TVTVKSSPSKSGKQLLK---NVSGKAKPGELTAIMGPSGAGKSTLLNALagRRTGLGVSGEVLINGRPLD-- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 aaskLQPLRRDIQFIFQDPYasLDPRQTVgysiLEPLRVHGLLQGdagskrvawllervgllpehawrypheFSGGQRQR 471
Cdd:cd03213   77 ----KRSFRKIIGYVPQDDI--LHPTLTV----RETLMFAAKLRG---------------------------LSGGERKR 119
                        170       180
                 ....*....|....*....|....
gi 949724212 472 ICIARALALNPKVIIADESVSALD 495
Cdd:cd03213  120 VSIALELVSNPSLLFLDEPTSGLD 143
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
34-260 6.03e-13

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 71.80  E-value: 6.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdeMLLRRRNRQV--IELGEQSASQMRHvrgaDIAMIFQ 111
Cdd:PRK11174 368 PLNFTLPAGQRIALVGPSGAGKT----SLLNAL--LG-------FLPYQGSLKIngIELRELDPESWRK----HLSWVGQ 430
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EPMTslnpvftVGEQIAESIRLHQGASHEEAMVEAkrmLDQVRIPEakaILSRYPH-----------QLSGGMRQRVMIA 180
Cdd:PRK11174 431 NPQL-------PHGTLRDNVLLGNPDASDEQLQQA---LENAWVSE---FLPLLPQgldtpigdqaaGLSVGQAQRLALA 497
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 181 MALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIaDRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PRK11174 498 RALLQPCQLLLLDEPTASLDAHSEQLVMQALNAASRRQT--TLMVTHQLEDLAQW-DQIWVMQDGQIVQQGDYAELSQAG 574
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
335-546 8.25e-13

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 67.94  E-value: 8.25e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 335 REVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV----ESQRGEIIFNGQRIDTLAASklqplrrdiqfifqdp 410
Cdd:cd03220   33 GEFWALKDVSFEVPRGERIGLIGRNGAGKST----LLRLLagiyPPDSGTVTVRGRVSSLLGLG---------------- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 411 yASLDPRQTVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLlpEHAWRYP-HEFSGGQRQRICIARALALNPKVIIADE 489
Cdd:cd03220   93 -GGFNPELTGRENIYLNGRLLGLSRKEI-DEKIDEIIEFSEL--GDFIDLPvKTYSSGMKARLAFAIATALEPDILLIDE 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 490 SVSALDVSIRGQIINLMLDLQRELGIAyLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:cd03220  169 VLAVGDAAFQEKCQRRLRELLKQGKTV-ILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
312-617 1.02e-12

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 70.26  E-value: 1.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTL 391
Cdd:PRK09536   2 PMIDVSDLSVEFG-----------DTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEAL 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 392 AASKLQplrRDIQFIFQDPYASL--DPRQTVGYSiLEPLRVHGLLQGDAGSKRVAWLLERVGLlPEHAWRYPHEFSGGQR 469
Cdd:PRK09536  71 SARAAS---RRVASVPQDTSLSFefDVRQVVEMG-RTPHRSRFDTWTETDRAAVERAMERTGV-AQFADRPVTSLSGGER 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 470 QRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:PRK09536 146 QRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPA 224
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 550 AVFENPQHPYTRKLMAAVpVADPSHHRPQRVLLSDDIPS--------NIRKRGEEISPVSLQLVGPGHYV-ARPLPE 617
Cdd:PRK09536 225 DVLTADTLRAAFDARTAV-GTDPATGAPTVTPLPDPDRTeaaadtrvHVVGGGQPAARAVSRLVAAGASVsVGPVPE 300
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
19-255 1.14e-12

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 70.62  E-value: 1.14e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  19 NIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQAGgEVSCDEMLLRRRNrqvieLGEQSASQM 98
Cdd:PRK11160 343 NVSFTYPDQPQPVLKGLSLQIKAGEKVALLGRTGCGKS----TLLQLLTRAW-DPQQGEILLNGQP-----IADYSEAAL 412
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  99 RhvrgADIAMIFQEpmtslnpVFTVGEQIAESIRLHQGASHEEAMVEakrMLDQV---RIPEAKAILS-------RyphQ 168
Cdd:PRK11160 413 R----QAISVVSQR-------VHLFSATLRDNLLLAAPNASDEALIE---VLQQVgleKLLEDDKGLNawlgeggR---Q 475
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALsCRPA-VLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIaDRVLVMYQGEA 247
Cdd:PRK11160 476 LSGGEQRRLGIARAL-LHDApLLLLDEPTEGLDAETERQILELLAEHAQNKT--VLMITHRLTGLEQF-DRICVMDNGQI 551

                 ....*...
gi 949724212 248 VETGSVEQ 255
Cdd:PRK11160 552 IEQGTHQE 559
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
329-552 1.47e-12

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 68.37  E-value: 1.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 329 ILNRVT---REVH-AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridtlaasklqPLRRDIQ 404
Cdd:PRK15056   8 VVNDVTvtwRNGHtALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQ-----------PTRQALQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 405 fifQDPYASLDPRQTVGYSIlePLRVH-----------GLLQGDAGSKR--VAWLLERVGLLpEHAWRYPHEFSGGQRQR 471
Cdd:PRK15056  77 ---KNLVAYVPQSEEVDWSF--PVLVEdvvmmgryghmGWLRRAKKRDRqiVTAALARVDMV-EFRHRQIGELSGGQKKR 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 472 ICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHrVAVMYLGQIVEIGTRRAV 551
Cdd:PRK15056 151 VFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPTETT 228

                 .
gi 949724212 552 F 552
Cdd:PRK15056 229 F 229
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
20-252 1.80e-12

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 68.68  E-value: 1.80e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  20 IAFEQEQQRVSA---VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVS-CDEMLLRRrnrqvielgeqsa 95
Cdd:PRK13537   8 IDFRNVEKRYGDklvVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISlCGEPVPSR------------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  96 sqMRHVRgADIAMIFQepMTSLNPVFTVGEQIAESIRlHQGASHEEAMVEAKRMLDQVRIpEAKAilSRYPHQLSGGMRQ 175
Cdd:PRK13537  75 --ARHAR-QRVGVVPQ--FDNLDPDFTVRENLLVFGR-YFGLSAAAARALVPPLLEFAKL-ENKA--DAKVGELSGGMKR 145
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 176 RVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqqdMSMG--VIFITHDMGVVADIADRVLVMYQGEAVETGS 252
Cdd:PRK13537 146 RLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSL---LARGktILLTTHFMEEAERLCDRLCVIEEGRKIAEGA 221
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
335-495 2.82e-12

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 70.06  E-value: 2.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  335 REVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRidTLAASKLQPLRRDIQFIFQDP---- 410
Cdd:PTZ00265  396 KDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSH--NLKDINLKWWRSKIGVVSQDPllfs 473
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  411 -------------------------------YASLDPRQTVGYS-------ILEPLRVHGLLQGDAG------------S 440
Cdd:PTZ00265  474 nsiknnikyslyslkdlealsnyynedgndsQENKNKRNSCRAKcagdlndMSNTTDSNELIEMRKNyqtikdsevvdvS 553
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212  441 KRVAwLLERVGLLPEhawRY-------PHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:PTZ00265  554 KKVL-IHDFVSALPD---KYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLD 611
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
10-244 3.19e-12

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 67.06  E-value: 3.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTAlslmhlieqaggevscdemllrrrnRQVIE 89
Cdd:PRK09544   2 TSLVSLENVSVSFGQRR----VLSDVSLELKPGKILTLLGPNGAGKSTLV-------------------------RVVLG 52
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGEQSASQMRHVRGADIAMIFQEpmTSLNPvfTVGEQIAESIRLHQGASHEEAMVEAKRMldqvripEAKAILSRYPHQL 169
Cdd:PRK09544  53 LVAPDEGVIKRNGKLRIGYVPQK--LYLDT--TLPLTVNRFLRLRPGTKKEDILPALKRV-------QAGHLIDAPMQKL 121
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQ 244
Cdd:PRK09544 122 SGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNH 196
PTZ00243 PTZ00243
ABC transporter; Provisional
343-556 3.49e-12

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 69.81  E-value: 3.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  343 VSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQPLRRDIQFIFQDPY-------ASLD 415
Cdd:PTZ00243 1329 VSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREI---GAYGLRELRRQFSMIPQDPVlfdgtvrQNVD 1405
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  416 PrqtvgysILEplrvhgllqgdAGSKRVAWLLERVGLLPehawRYPHE--------------FSGGQRQRICIARA-LAL 480
Cdd:PTZ00243 1406 P-------FLE-----------ASSAEVWAALELVGLRE----RVASEsegidsrvleggsnYSVGQRQLMCMARAlLKK 1463
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  481 NPKVIIADESVSALDVSIRGQIINLMldlqRELGIAYLFIShdmavverISHR---VA------VMYLGQIVEIGTRRAV 551
Cdd:PTZ00243 1464 GSGFILMDEATANIDPALDRQIQATV----MSAFSAYTVIT--------IAHRlhtVAqydkiiVMDHGAVAEMGSPREL 1531

                  ....*
gi 949724212  552 FENPQ 556
Cdd:PTZ00243 1532 VMNRQ 1536
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
145-536 4.55e-12

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 69.07  E-value: 4.55e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 145 EAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALScRPA-VLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVI 223
Cdd:PRK13409 189 ERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALL-RDAdFYFFDEPTSYLDIRQRLNVARLIRELAEGKY--VL 265
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 224 FITHDMGVVADIADRVLVMYqGEAvetgSVEQIFhapQHPYtkallaavpqlGAMNG------HELP------RRFPLI- 290
Cdd:PRK13409 266 VVEHDLAVLDYLADNVHIAY-GEP----GAYGVV---SKPK-----------GVRVGineylkGYLPeenmriRPEPIEf 326
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 291 SLHDPshvEPQTEQDTVVEGEPIlrVRNLVTrFPLrsgilnrvtrEVHAVEnvsfdLWPGETLSLVGESGCGKSTTGRAL 370
Cdd:PRK13409 327 EERPP---RDESERETLVEYPDL--TKKLGD-FSL----------EVEGGE-----IYEGEVIGIVGPNGIGKTTFAKLL 385
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 371 LRLVESQRGEIIFNgQRIdtlaASKLQPLRRDIQFIFQDPYASLDPRQTVGY---SILEPLRVHGLLQgdagsKRVAwll 447
Cdd:PRK13409 386 AGVLKPDEGEVDPE-LKI----SYKPQYIKPDYDGTVEDLLRSITDDLGSSYyksEIIKPLQLERLLD-----KNVK--- 452
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 448 ervgllpehawryphEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVV 527
Cdd:PRK13409 453 ---------------DLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDIYMI 517

                 ....*....
gi 949724212 528 ERISHRVAV 536
Cdd:PRK13409 518 DYISDRLMV 526
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
339-534 5.77e-12

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 64.95  E-value: 5.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIifngqRIDTLAASKLQPLRRDIqfifqDPYASLDPRQ 418
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV-----RRAGGARVAYVPQRSEV-----PDSLPLTVRD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 TVGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSI 498
Cdd:NF040873  77 LVAMGRWARRGLWRRLTRDD-RAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAES 154
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 949724212 499 RGQIINLMLDLQRElGIAYLFISHDMAVVERISHRV 534
Cdd:NF040873 155 RERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
31-228 6.20e-12

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 68.16  E-value: 6.20e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQMRHVRGADIAMIF 110
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLD--------------GVPVSSLDQDEVRRRVSVCA 415
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  111 QEPMtslnpVFtvGEQIAESIRLHQG-ASHEEAMveakRMLDQVRIPEakaILSRYPH-----------QLSGGMRQRVM 178
Cdd:TIGR02868 416 QDAH-----LF--DTTVRENLRLARPdATDEELW----AALERVGLAD---WLRALPDgldtvlgeggaRLSGGERQRLA 481
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 949724212  179 IAMALSCRPAVLIADEPTTALDVTIQAQILQLIkvLQQDMSMGVIFITHD 228
Cdd:TIGR02868 482 LARALLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVLITHH 529
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
32-227 6.73e-12

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 64.10  E-value: 6.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvielgeqsasqmrhvrGADIAMIFQ 111
Cdd:cd03223   17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPE-------------------------GEDLLFLPQ 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EPMTslnPVFTVGEQIAesirlhqgasheeamveakrmldqvripeakailsrYP--HQLSGGMRQRVMIAMALSCRPAV 189
Cdd:cd03223   72 RPYL---PLGTLREQLI------------------------------------YPwdDVLSGGEQQRLAFARLLLHKPKF 112
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 949724212 190 LIADEPTTALDVTIQAQILQLIKvlqqDMSMGVIFITH 227
Cdd:cd03223  113 VFLDEATSALDEESEDRLYQLLK----ELGITVISVGH 146
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
350-547 7.28e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 68.82  E-value: 7.28e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   350 GETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlAASKLQPLRRDIQFIFQDPY-------ASLDPRQTvgY 422
Cdd:TIGR00957 1312 GEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNI---AKIGLHDLRFKITIIPQDPVlfsgslrMNLDPFSQ--Y 1386
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   423 SileplrvhgllqgdagSKRVAWLLER------VGLLPEhawRYPHE-------FSGGQRQRICIARALALNPKVIIADE 489
Cdd:TIGR00957 1387 S----------------DEEVWWALELahlktfVSALPD---KLDHEcaeggenLSVGQRQLVCLARALLRKTKILVLDE 1447
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212   490 SVSALDVSIrGQIINLMLDLQRElGIAYLFISHDMAVVERIShRVAVMYLGQIVEIGT 547
Cdd:TIGR00957 1448 ATAAVDLET-DNLIQSTIRTQFE-DCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGA 1502
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
338-549 8.19e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 65.91  E-value: 8.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaASKLQPLRRDIQFIFQDPyasldPR 417
Cdd:PRK13647  19 KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVN---AENEKWVRSKVGLVFQDP-----DD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILE-----PLRVHglLQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVS 492
Cdd:PRK13647  91 QVFSSTVWDdvafgPVNMG--LDKDEVERRVEEALKAVRMW-DFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMA 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 493 ALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRR 549
Cdd:PRK13647 168 YLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKS 223
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
21-260 8.37e-12

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 67.82  E-value: 8.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  21 AFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLMhlieQAGGEVSCDEMLLRRRNRQVIELGEQSASqmrh 100
Cdd:PRK10789 320 QFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKS-TLLSLI----QRHFDVSEGDIRFHDIPLTKLQLDSWRSR---- 390
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 101 vrgadIAMIFQEPmtslnpvFTVGEQIAESIRLHQGASHEEAMVEAKRML----DQVRIPEAkailsrYPHQ-------L 169
Cdd:PRK10789 391 -----LAVVSQTP-------FLFSDTVANNIALGRPDATQQEIEHVARLAsvhdDILRLPQG------YDTEvgergvmL 452
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADiADRVLVMYQGEAVE 249
Cdd:PRK10789 453 SGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGEGRT--VIISAHRLSALTE-ASEILVMQHGHIAQ 529
                        250
                 ....*....|.
gi 949724212 250 TGSVEQIFHAP 260
Cdd:PRK10789 530 RGNHDQLAQQS 540
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
311-548 9.50e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 67.72  E-value: 9.50e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFPlrsgilnrvtrEVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDt 390
Cdd:PRK10762   2 QALLQLKGIDKAFP-----------GVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVT- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 391 laasklqplrrdiqfiFQDPYASldprQTVGYSIL--------------------EPLRVHGLLQGDAGSKRVAWLLERV 450
Cdd:PRK10762  70 ----------------FNGPKSS----QEAGIGIIhqelnlipqltiaeniflgrEFVNRFGRIDWKKMYAEADKLLARL 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 451 GLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRE-LGIAYlfISHDMAVVER 529
Cdd:PRK10762 130 NL-RFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQgRGIVY--ISHRLKEIFE 206
                        250
                 ....*....|....*....
gi 949724212 530 ISHRVAVMYLGQIveIGTR 548
Cdd:PRK10762 207 ICDDVTVFRDGQF--IAER 223
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
341-551 1.17e-11

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 65.39  E-value: 1.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQplrRDIQFIFQDpyASLDPRQTV 420
Cdd:PRK10253  24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA---RRIGLLAQN--ATTPGDITV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 421 ------GYSILEPLRVHGLLQGDAGskrVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK10253  99 qelvarGRYPHQPLFTRWRKEDEEA---VTKAMQATGI-THLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWL 174
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 495 DVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:PRK10253 175 DISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEI 231
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
11-249 1.32e-11

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 67.40  E-value: 1.32e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  11 DVLAVSNLNIAFEQEQQrvsaVRNLSFRLKRGETLAIVGESGSGKSvTALS-LMHLIEQAGGEVscdemllrrrnrqviE 89
Cdd:COG0488  314 KVLELEGLSKSYGDKTL----LDDLSLRIDRGDRIGLIGPNGAGKS-TLLKlLAGELEPDSGTV---------------K 373
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGEqsasqmrhvrGADIAMIFQEpMTSLNPVFTVGEQIAesiRLHQGASHEEAMVEAKRML---DQVRipeaKAIlsryp 166
Cdd:COG0488  374 LGE----------TVKIGYFDQH-QEELDPDKTVLDELR---DGAPGGTEQEVRGYLGRFLfsgDDAF----KPV----- 430
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDV-TIQAqilqLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQG 245
Cdd:COG0488  431 GVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIeTLEA----LEEAL-DDFPGTVLLVSHDRYFLDRVATRILEFEDG 505

                 ....
gi 949724212 246 EAVE 249
Cdd:COG0488  506 GVRE 509
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
339-547 1.36e-11

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 65.19  E-value: 1.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLwPGETL--------------SLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridTLAASKLQPLRRDIQ 404
Cdd:PRK10575  13 ALRNVSFRV-PGRTLlhplsltfpagkvtGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQ---PLESWSSKAFARKVA 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 405 FIFQD-PYASldprqtvGYSILEPLRV-----HGLLQ--GDAGSKRVAWLLERVGLLPeHAWRYPHEFSGGQRQRICIAR 476
Cdd:PRK10575  89 YLPQQlPAAE-------GMTVRELVAIgrypwHGALGrfGAADREKVEEAISLVGLKP-LAHRLVDSLSGGERQRAWIAM 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 477 ALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGT 547
Cdd:PRK10575 161 LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
165-242 1.64e-11

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 62.47  E-value: 1.64e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 165 YPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQdmsmGVIFITHDMGVVADIADRVLVM 242
Cdd:cd03221   67 YFEQLSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEYPG----TVILVSHDRYFLDQVATKIIEL 140
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
12-255 2.45e-11

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 66.29  E-value: 2.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNiafeqeQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRN-RQVIEL 90
Cdd:PRK10982 250 ILEVRNLT------SLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNaNEAINH 323
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  91 GEQSASQMRHVRGadiamIFQEPMTSLNPVFTVGEQIAESIRLhqgASHEEAMVEAKRMLDQVRI--PEAKAILSryphQ 168
Cdd:PRK10982 324 GFALVTEERRSTG-----IYAYLDIGFNSLISNIRNYKNKVGL---LDNSRMKSDTQWVIDSMRVktPGHRTQIG----S 391
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEA- 247
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRILVMSNGLVa 470
                        250
                 ....*....|
gi 949724212 248 --VETGSVEQ 255
Cdd:PRK10982 471 giVDTKTTTQ 480
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
340-551 2.79e-11

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 63.95  E-value: 2.79e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTtgraLL----RLVESQRGEIIFNGQRIDTLA----ASKLQPLRRDIQFIfqdpy 411
Cdd:COG4604   17 LDDVSLTIPKGGITALIGPNGAGKST----LLsmisRLLPPDSGEVLVDGLDVATTPsrelAKRLAILRQENHIN----- 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 412 ASLDPRQTVG-----YSileplrvHGLLqGDAGSKRVAWLLERVGLLP-EHawRYPHEFSGGQRQRICIARALALNPKVI 485
Cdd:COG4604   88 SRLTVRELVAfgrfpYS-------KGRL-TAEDREIIDEAIAYLDLEDlAD--RYLDELSGGQRQRAFIAMVLAQDTDYV 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 486 IADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAV 551
Cdd:COG4604  158 LLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEI 223
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
325-554 3.53e-11

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 63.88  E-value: 3.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 325 LRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRG-----EIIFNGQRIDTLAASKLQPL 399
Cdd:PRK09984   5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSagshiELLGRTVQREGRLARDIRKS 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 400 RRDIQFIFQDpyASLDPRQTVGYSIL------EPL-RVHGLLQGDAGSKRVAWLLERVGLLpEHAWRYPHEFSGGQRQRI 472
Cdd:PRK09984  85 RANTGYIFQQ--FNLVNRLSVLENVLigalgsTPFwRTCFSWFTREQKQRALQALTRVGMV-HFAHQRVSTLSGGQQQRV 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 473 CIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAvF 552
Cdd:PRK09984 162 AIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ-F 240

                 ..
gi 949724212 553 EN 554
Cdd:PRK09984 241 DN 242
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
34-288 4.00e-11

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 64.02  E-value: 4.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGGEVSCD--EMLLRRRNrqvieLGEQSASQMRHVRgADIAMIFQ 111
Cdd:PRK11831  25 NISLTVPRGKITAIMGPSGIGKT----TLLRLI---GGQIAPDhgEILFDGEN-----IPAMSRSRLYTVR-KRMSMLFQ 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EP--MTSLNPVFTVGEQIAESIRLHQGASHEEAMVEakrmLDQVRIPEAKAILsryPHQLSGGMRQRVMIAMALSCRPAV 189
Cdd:PRK11831  92 SGalFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMK----LEAVGLRGAAKLM---PSELSGGMARRAALARAIALEPDL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 190 LIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIfHAPQHPYTKALL 269
Cdd:PRK11831 165 IMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL-QANPDPRVRQFL 243
                        250
                 ....*....|....*....
gi 949724212 270 AavpqlGAMNGhELPRRFP 288
Cdd:PRK11831 244 D-----GIADG-PVPFRYP 256
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
32-256 4.68e-11

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 63.12  E-value: 4.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDE-------MLLRRRnrqvieLGeqsasqmrhvrga 104
Cdd:COG1137   19 VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGedithlpMHKRAR------LG------------- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 105 dIAMIFQEPmtSlnpVF---TVGEQIAeSIRLHQGASHEEAMVEAKRMLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAM 181
Cdd:COG1137   80 -IGYLPQEA--S---IFrklTVEDNIL-AVLELRKLSKKEREERLEELLEEFGI---THLRKSKAYSLSGGERRRVEIAR 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 182 ALSCRPAVLIADEPTTALD---VT-IQAQILQLikvlqQDMSMGVIfIT-HDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:COG1137  150 ALATNPKFILLDEPFAGVDpiaVAdIQKIIRHL-----KERGIGVL-ITdHNVRETLGICDRAYIISEGKVLAEGTPEEI 223
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
31-259 5.39e-11

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 65.51  E-value: 5.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGET--------------LAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrNRQVIELGEQSAS 96
Cdd:PRK10790 342 DIDNVSFAYRDDNLvlqninlsvpsrgfVALVGHTGSGKSTLASLLMGYYPLTEGEIRLD-------GRPLSSLSHSVLR 414
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  97 QmrhvrgaDIAMIFQEPMTSLNPVF---TVGEQIAESirlhqgasHEEAMVEAKRMLDQVR-IPEAkaILSRYPHQ---L 169
Cdd:PRK10790 415 Q-------GVAMVQQDPVVLADTFLanvTLGRDISEE--------QVWQALETVQLAELARsLPDG--LYTPLGEQgnnL 477
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMgvIFITHDMGVVADiADRVLVMYQGEAVE 249
Cdd:PRK10790 478 SVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTL--VVIAHRLSTIVE-ADTILVLHRGQAVE 554
                        250
                 ....*....|
gi 949724212 250 TGSVEQIFHA 259
Cdd:PRK10790 555 QGTHQQLLAA 564
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
10-258 5.54e-11

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 62.28  E-value: 5.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  10 SDVLAVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSvtaLSLMHLIEQAGGEVSCdemllrrrNRQVIE 89
Cdd:cd03233    1 ASTLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCS---TLLKALANRTEGNVSV--------EGDIHY 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGEQSASQMRHVRGaDIAMIFQEpmTSLNPVFTVGEQIAESIRLhQGasheeamveakrmldqvripeakailSRYPHQL 169
Cdd:cd03233   70 NGIPYKEFAEKYPG-EIIYVSEE--DVHFPTLTVRETLDFALRC-KG--------------------------NEFVRGI 119
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVA-DIADRVLVMYQGeav 248
Cdd:cd03233  120 SGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDEIyDLFDKVLVLYEG--- 196
                        250
                 ....*....|
gi 949724212 249 etgsvEQIFH 258
Cdd:cd03233  197 -----RQIYY 201
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
314-554 5.88e-11

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 63.39  E-value: 5.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 314 LRVRNLVTRFplrSGILNRVTREVHAVENvsfdlwPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAa 393
Cdd:cd03288   20 IKIHDLCVRY---ENNLKPVLKHVKAYIK------PGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLP- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 394 skLQPLRRDIQFIFQDPYA-------SLDPRQTVGYSIL-EPLRVHGLlqgdagsKRVAWLLErvGLLPEHAWRYPHEFS 465
Cdd:cd03288   90 --LHTLRSRLSIILQDPILfsgsirfNLDPECKCTDDRLwEALEIAQL-------KNMVKSLP--GGLDAVVTEGGENFS 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 466 GGQRQRICIARALALNPKVIIADESVSALDVSIRgqiiNLmldLQRELGIAYLfishDMAVVErISHRVAVMYLGQIVEI 545
Cdd:cd03288  159 VGQRQLFCLARAFVRKSSILIMDEATASIDMATE----NI---LQKVVMTAFA----DRTVVT-IAHRVSTILDADLVLV 226

                 ....*....
gi 949724212 546 GTRRAVFEN 554
Cdd:cd03288  227 LSRGILVEC 235
PLN03130 PLN03130
ABC transporter C family member; Provisional
343-547 7.18e-11

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 65.53  E-value: 7.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  343 VSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAaskLQPLRRDIQFIFQDPYASldpRQTVGY 422
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFG---LMDLRKVLGIIPQAPVLF---SGTVRF 1331
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  423 SiLEPLRVHgllqGDAGskrvAW-LLERVGL----------LPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:PLN03130 1332 N-LDPFNEH----NDAD----LWeSLERAHLkdvirrnslgLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEAT 1402
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212  492 SALDVSIRGQIinlmldlQRElgIAYLFISHDMAVverISHR---------VAVMYLGQIVEIGT 547
Cdd:PLN03130 1403 AAVDVRTDALI-------QKT--IREEFKSCTMLI---IAHRlntiidcdrILVLDAGRVVEFDT 1455
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
339-528 7.26e-11

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 61.99  E-value: 7.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASklqpLRRDIQFIFQDPyaSLDPRQ 418
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDE----PHENILYLGHLP--GLKPEL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  419 TVgysiLEPLRVHGLLQGDAgsKRVAW-LLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:TIGR01189  89 SA----LENLHFWAAIHGGA--QRTIEdALAAVGLT-GFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKA 161
                         170       180       190
                  ....*....|....*....|....*....|..
gi 949724212  498 IRGQIINLMLD-LQRElGIAYLFISHDMAVVE 528
Cdd:TIGR01189 162 GVALLAGLLRAhLARG-GIVLLTTHQDLGLVE 192
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
3-242 9.15e-11

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 61.90  E-value: 9.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   3 HSDELDASD-VLAV-SNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTalsLMHLIEQAGGEVSCDEMLL 80
Cdd:COG2401   17 YSSVLDLSErVAIVlEAFGVELRVVERYV--LRDLNLEIEPGEIVLIVGASGSGKSTL---LRLLAGALKGTPVAGCVDV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  81 rrrnrQVIELGEQSAsqmrhvrgadiamifqepmtslnpvftvgeqIAESIrlhqgaSHEEAMVEAKRMLDQVRIPEAKA 160
Cdd:COG2401   92 -----PDNQFGREAS-------------------------------LIDAI------GRKGDFKDAVELLNAVGLSDAVL 129
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRYPHqLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTiQAQILQL-IKVLQQDMSMGVIFITHDMGVVADIADRV 239
Cdd:COG2401  130 WLRRFKE-LSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQ-TAKRVARnLQKLARRAGITLVVATHHYDVIDDLQPDL 207

                 ...
gi 949724212 240 LVM 242
Cdd:COG2401  208 LIF 210
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
340-522 1.61e-10

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 64.00  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  340 VENVSFDLWPGETLSLVGESGCGKSTTGRALlrlvesqrGEI--IFNGQRIdtlaasklQPLRRDIQFIFQDPYASL--- 414
Cdd:TIGR00954 468 IESLSFEVPSGNNLLICGPNGCGKSSLFRIL--------GELwpVYGGRLT--------KPAKGKLFYVPQRPYMTLgtl 531
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  415 ----------DPRQTVGYS------ILEPLRVHGLLQGDAGSKRVA-WLlervgllpehawrypHEFSGGQRQRICIARA 477
Cdd:TIGR00954 532 rdqiiypdssEDMKRRGLSdkdleqILDNVQLTHILEREGGWSAVQdWM---------------DVLSGGEKQRIAMARL 596
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 949724212  478 LALNPKVIIADESVSALDVSIRGQIINLMldlqRELGIAYLFISH 522
Cdd:TIGR00954 597 FYHKPQFAILDECTSAVSVDVEGYMYRLC----REFGITLFSVSH 637
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
340-544 1.84e-10

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 62.93  E-value: 1.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaASKLQPLRRDIQFIFQdpYASLDPRQT 419
Cdd:PRK13536  57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPV----PARARLARARIGVVPQ--FDNLDLEFT 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 VGYSILEPLRVHGLLQGDAgSKRVAWLLERVGLLPEHAWRYPhEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR 499
Cdd:PRK13536 131 VRENLLVFGRYFGMSTREI-EAVIPSLLEFARLESKADARVS-DLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHAR 208
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 949724212 500 gqiiNLMLDLQREL---GIAYLFISHDMAVVERISHRVAVMYLG-QIVE 544
Cdd:PRK13536 209 ----HLIWERLRSLlarGKTILLTTHFMEEAERLCDRLCVLEAGrKIAE 253
hmuV PRK13547
heme ABC transporter ATP-binding protein;
332-557 1.99e-10

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 61.77  E-value: 1.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 332 RVTREVHAV-ENVSFDLWPGETLSLVGESGCGKSTTGRALL-RLVESQ-------RGEIIFNGQRIDTLAASKLQPLRRD 402
Cdd:PRK13547   8 HVARRHRAIlRDLSLRIEPGRVTALLGRNGAGKSTLLKALAgDLTGGGaprgarvTGDVTLNGEPLAAIDAPRLARLRAV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 403 IQFIFQDPYAsLDPRQTVGYSILEPLRVHGLLQGDAGSkrVAW-LLERVGLLPEHAwRYPHEFSGGQRQRICIARALA-- 479
Cdd:PRK13547  88 LPQAAQPAFA-FSAREIVLLGRYPHARRAGALTHRDGE--IAWqALALAGATALVG-RDVTTLSGGELARVQFARVLAql 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 480 -------LNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVF 552
Cdd:PRK13547 164 wpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVL 243

                 ....*
gi 949724212 553 EnPQH 557
Cdd:PRK13547 244 T-PAH 247
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
315-568 3.21e-10

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 63.14  E-value: 3.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  315 RVRNLVTRFPLRSGILNrvtrevhaveNVSFDLWPGETLSLVGESGCGKSTTGRALlrlveSQR--------GEIIFNGQ 386
Cdd:TIGR00955  26 RLRGCFCRERPRKHLLK----------NVSGVAKPGELLAVMGSSGAGKTTLMNAL-----AFRspkgvkgsGSVLLNGM 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  387 RIDtlaaskLQPLRRDIQFIFQDP--YASLDPRQTVGYSILepLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHE- 463
Cdd:TIGR00955  91 PID------AKEMRAISAYVQQDDlfIPTLTVREHLMFQAH--LRMPRRVTKKEKRERVDEVLQALGLRKCANTRIGVPg 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  464 ----FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAVMYL 539
Cdd:TIGR00955 163 rvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAE 242
                         250       260       270
                  ....*....|....*....|....*....|.
gi 949724212  540 GQIVEIGTrravfenPQH--PYTRKLMAAVP 568
Cdd:TIGR00955 243 GRVAYLGS-------PDQavPFFSDLGHPCP 266
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
299-547 3.85e-10

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 63.49  E-value: 3.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   299 EPQTEQDTVVEGE-----------PILRVRNLVTRFPLRSGilnrvtrevHAVENVSFDLWPGETLSLVGESGCGKSTTG 367
Cdd:TIGR01257 1912 EPIFDEDDDVAEErqriisggnktDILRLNELTKVYSGTSS---------PAVDRLCVGVRPGECFGLLGVNGAGKTTTF 1982
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   368 RALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIQFIFQDPYasLDPRqtvgysilEPLRVHGLLQGDAGS--KRVA- 444
Cdd:TIGR01257 1983 KMLTGDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL--LTGR--------EHLYLYARLRGVPAEeiEKVAn 2052
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   445 WLLERVGlLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDM 524
Cdd:TIGR01257 2053 WSIQSLG-LSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSM 2130
                          250       260
                   ....*....|....*....|...
gi 949724212   525 AVVERISHRVAVMYLGQIVEIGT 547
Cdd:TIGR01257 2131 EECEALCTRLAIMVKGAFQCLGT 2153
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
12-255 4.36e-10

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 60.80  E-value: 4.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLRRRNRQvielg 91
Cdd:PRK09984   4 IIRVEKLAKTFNQHQ----ALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLGRTVQRE----- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 EQSASQMRHVRgADIAMIFQEpmTSLNPVFTVGEQIaesirLHQGASHEEAMVEAKRMLDQVRIPEAKAILSR-----YP 166
Cdd:PRK09984  75 GRLARDIRKSR-ANTGYIFQQ--FNLVNRLSVLENV-----LIGALGSTPFWRTCFSWFTREQKQRALQALTRvgmvhFA 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 167 HQ----LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVM 242
Cdd:PRK09984 147 HQrvstLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVAL 226
                        250
                 ....*....|...
gi 949724212 243 YQGEAVETGSVEQ 255
Cdd:PRK09984 227 RQGHVFYDGSSQQ 239
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
340-513 7.67e-10

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 59.27  E-value: 7.67e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRR-DIQFIFQDPY---ASLD 415
Cdd:cd03290   17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRySVAYAAQKPWllnATVE 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGySILEPLRVHGLLqgDAGSkrvawLLERVGLLPEHAWRYPHE----FSGGQRQRICIARALALNPKVIIADESV 491
Cdd:cd03290   97 ENITFG-SPFNKQRYKAVT--DACS-----LQPDIDLLPFGDQTEIGErginLSGGQRQRICVARALYQNTNIVFLDDPF 168
                        170       180
                 ....*....|....*....|....*..
gi 949724212 492 SALDVSIRGQ-----IINLMLDLQREL 513
Cdd:cd03290  169 SALDIHLSDHlmqegILKFLQDDKRTL 195
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
32-254 8.16e-10

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 58.69  E-value: 8.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHL--IEQAGGEvscdemllrrrnrqvIELGEQSASQM----RHVRGad 105
Cdd:cd03217   16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGE---------------ILFKGEDITDLppeeRARLG-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 106 IAMIFQEPmtslnpvftvgeqiaesirlhqgasheeamveakrmldqVRIPEAK-AILSRYPHQ-LSGGMRQRVMIAMAL 183
Cdd:cd03217   79 IFLAFQYP---------------------------------------PEIPGVKnADFLRYVNEgFSGGEKKRNEILQLL 119
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADI-ADRVLVMYQGEAVETGSVE 254
Cdd:cd03217  120 LLEPDLAILDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKE 190
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
29-245 8.19e-10

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 59.27  E-value: 8.19e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  29 VSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMLLrrrnrqvielGEQSASQMRHVRGADIAM 108
Cdd:cd03290   14 LATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNE----------SEPSFEATRSRNRYSVAY 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 109 IFQEPMTsLNPvfTVGEQIAESIRLHQgaSHEEAMVEAKRML---------DQVRIPEaKAIlsryphQLSGGMRQRVMI 179
Cdd:cd03290   84 AAQKPWL-LNA--TVEENITFGSPFNK--QRYKAVTDACSLQpdidllpfgDQTEIGE-RGI------NLSGGQRQRICV 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 180 AMALSCRPAVLIADEPTTALDVTIQAQILQ--LIKVLQQDMSMgVIFITHDMGVVADiADRVLVMYQG 245
Cdd:cd03290  152 ARALYQNTNIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRT-LVLVTHKLQYLPH-ADWIIAMKDG 217
oligo_HPY TIGR01727
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...
246-276 9.63e-10

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 213647 [Multi-domain]  Cd Length: 87  Bit Score: 55.45  E-value: 9.63e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 949724212  246 EAVETGSVEQIFHAPQHPYTKALLAAVPQLG 276
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIK 31
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
12-234 1.07e-09

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 58.66  E-value: 1.07e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLniAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLI----EQAGGEVS-CDEMLLRRR--- 83
Cdd:PRK13538   1 MLEARNL--ACERDERIL--FSGLSFTLNAGELVQIEGPNGAGKT----SLLRILaglaRPDAGEVLwQGEPIRRQRdey 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  84 NRQVIELGEQSAsqmrhvrgadiamifqepmtsLNPVFTVGEQIAESIRLHQGAShEEAMVEAkrmLDQVRipeakaiLS 163
Cdd:PRK13538  73 HQDLLYLGHQPG---------------------IKTELTALENLRFYQRLHGPGD-DEALWEA---LAQVG-------LA 120
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 164 RY---P-HQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLikvLQQDMSMG--VIFITH-DMGVVAD 234
Cdd:PRK13538 121 GFedvPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLEAL---LAQHAEQGgmVILTTHqDLPVASD 195
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
311-552 1.18e-09

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 59.33  E-value: 1.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNlVTrfplrsgilnrVTR-EVHAVENVSFDLWPGETLSLVGESGCGKSTtgraLLRLV-----ESQRGEIIFN 384
Cdd:COG1119    1 DPLLELRN-VT-----------VRRgGKTILDDISWTVKPGEHWAILGPNGAGKST----LLSLItgdlpPTYGNDVRLF 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 385 GQRidtLAASKLQPLRRDIQFIFQDPYASLDPRQTV-------GYSILeplrvhGLLQ--GDAGSKRVAWLLERVGLLpE 455
Cdd:COG1119   65 GER---RGGEDVWELRKRIGLVSPALQLRFPRDETVldvvlsgFFDSI------GLYRepTDEQRERARELLELLGLA-H 134
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 456 HAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMA-VVERISHrV 534
Cdd:COG1119  135 LADRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEeIPPGITH-V 213
                        250
                 ....*....|....*...
gi 949724212 535 AVMYLGQIVEIGTRRAVF 552
Cdd:COG1119  214 LLLKDGRVVAAGPKEEVL 231
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
342-547 1.25e-09

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 61.01  E-value: 1.25e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVeSQRGEIIFNGQRIDTLAaskLQPLRRDIQFIFQDPyaSLdPRQTVG 421
Cdd:PRK11174 368 PLNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRELD---PESWRKHLSWVGQNP--QL-PHGTLR 440
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 422 YSILeplrvhgLLQGDAGSKRV------AWLLERVGLLP--------EHAWRypheFSGGQRQRICIARALALNPKVIIA 487
Cdd:PRK11174 441 DNVL-------LGNPDASDEQLqqalenAWVSEFLPLLPqgldtpigDQAAG----LSVGQAQRLALARALLQPCQLLLL 509
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 488 DESVSALDVSIRGQIINLMLDLQRelGIAYLFISH---DMAVVERIshrvAVMYLGQIVEIGT 547
Cdd:PRK11174 510 DEPTASLDAHSEQLVMQALNAASR--RQTTLMVTHqleDLAQWDQI----WVMQDGQIVQQGD 566
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
159-536 1.46e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 60.95  E-value: 1.46e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 159 KAILSRYPHQLSGGMRQRVMIAMALScRPA-VLIADEPTTALDVTIQAQILQLIKVLQQDMSMgVIFITHDMGVVADIAD 237
Cdd:COG1245  203 ENILDRDISELSGGELQRVAIAAALL-RDAdFYFFDEPSSYLDIYQRLNVARLIRELAEEGKY-VLVVEHDLAILDYLAD 280
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 238 RVLVMYqGEAVETGSVEQIfhapqhpytKALLAAVPQLgaMNGHeLP------RRFPLI-SLHDPShvepqteqdTVVEG 310
Cdd:COG1245  281 YVHILY-GEPGVYGVVSKP---------KSVRVGINQY--LDGY-LPeenvriRDEPIEfEVHAPR---------REKEE 338
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 311 EPILRVRNLVTRFP-----LRSGILNRvtrevhavenvsfdlwpGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNg 385
Cdd:COG1245  339 ETLVEYPDLTKSYGgfsleVEGGEIRE-----------------GEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED- 400
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 386 QRIdtlaASKLQPLRRDI-----QFIFQdpyASLDPRQTVGY--SILEPLRVHGLLQgdagsKRVAwllervgllpehaw 458
Cdd:COG1245  401 LKI----SYKPQYISPDYdgtveEFLRS---ANTDDFGSSYYktEIIKPLGLEKLLD-----KNVK-------------- 454
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 459 ryphEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERISHRVAV 536
Cdd:COG1245  455 ----DLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMV 528
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
32-252 1.56e-09

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 61.11  E-value: 1.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrnrQVIELGeqsasqmRHVRGADIAMIFQ 111
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGL-------NIAKIG-------LHDLRFKITIIPQ 1367
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   112 EPM-------TSLNPVFTVG-EQIAESIRLhqgaSHEEAMVEAkrMLDQVRIPEAKAilsryPHQLSGGMRQRVMIAMAL 183
Cdd:TIGR00957 1368 DPVlfsgslrMNLDPFSQYSdEEVWWALEL----AHLKTFVSA--LPDKLDHECAEG-----GENLSVGQRQLVCLARAL 1436
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212   184 SCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmgVIFITHDMGVVADIAdRVLVMYQGEAVETGS 252
Cdd:TIGR00957 1437 LRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCT--VLTIAHRLNTIMDYT-RVIVLDKGEVAEFGA 1502
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
31-211 1.65e-09

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 57.75  E-value: 1.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   31 AVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqAGgevscdemlLRRRNRQVIELGEQSASQMRHVRGADIAMIF 110
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKT----TLLRIL--AG---------LLRPDSGEVRWNGTPLAEQRDEPHENILYLG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  111 QEPmtSLNPVFTVGEQIAESIRLHQGASHE-EAMVEAKRMLDQVRIPeakailsryPHQLSGGMRQRVMIAMALSCRPAV 189
Cdd:TIGR01189  80 HLP--GLKPELSALENLHFWAAIHGGAQRTiEDALAAVGLTGFEDLP---------AAQLSAGQQRRLALARLWLSRRPL 148
                         170       180
                  ....*....|....*....|..
gi 949724212  190 LIADEPTTALDVTIQAQILQLI 211
Cdd:TIGR01189 149 WILDEPTTALDKAGVALLAGLL 170
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
13-246 2.16e-09

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 57.48  E-value: 2.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVSAV-RNLSFRLKRGETLAIVGESGSGKSVTALSLMhlieqagGEvscdemlLRRRNRQVielg 91
Cdd:cd03250    1 ISVEDASFTWDSGEQETSFTlKDINLEVPKGELVAIVGPVGSGKSSLLSALL-------GE-------LEKLSGSV---- 62
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  92 eqsasqmrHVRGAdIAMIFQEPmtslnpvFTVGEQIAESIRLHQGASHE--EAMVEA-------KRM--LDQVRIPEaKA 160
Cdd:cd03250   63 --------SVPGS-IAYVSQEP-------WIQNGTIRENILFGKPFDEEryEKVIKAcalepdlEILpdGDLTEIGE-KG 125
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 IlsryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQliKVLQQDMSMG--VIFITHDMGVVADiADR 238
Cdd:cd03250  126 I------NLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIFE--NCILGLLLNNktRILVTHQLQLLPH-ADQ 196

                 ....*...
gi 949724212 239 VLVMYQGE 246
Cdd:cd03250  197 IVVLDNGR 204
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
138-256 2.64e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 59.36  E-value: 2.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 138 SHEEAMVEAKRMLDQVRIPEAKAilsRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQD 217
Cdd:NF000106 117 SRKDARARADELLERFSLTEAAG---RAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD 193
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 949724212 218 MSMgVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQI 256
Cdd:NF000106 194 GAT-VLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
oligo_HPY pfam08352
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...
543-572 2.64e-09

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.


Pssm-ID: 400588 [Multi-domain]  Cd Length: 65  Bit Score: 53.56  E-value: 2.64e-09
                          10        20        30
                  ....*....|....*....|....*....|
gi 949724212  543 VEIGTRRAVFENPQHPYTRKLMAAVPVADP 572
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDP 30
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
292-547 3.42e-09

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 60.41  E-value: 3.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   292 LHDPSHvePQTEQDTVVEGE-----PILRVRNLVTRF-PLRSGILNRVtrevhaveNVSFdlWPGETLSLVGESGCGKST 365
Cdd:TIGR01257  904 MEDPEH--PEGINDSFFERElpglvPGVCVKNLVKIFePSGRPAVDRL--------NITF--YENQITAFLGHNGAGKTT 971
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   366 TGRALLRLVESQRGEIIFNGQRIDTlaasKLQPLRRDIQFIFQdpYASLDPRQTVGYSILEPLRVHGLLQGDAGSKRVAw 445
Cdd:TIGR01257  972 TLSILTGLLPPTSGTVLVGGKDIET----NLDAVRQSLGMCPQ--HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEA- 1044
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   446 LLERVGLlpeHAWR--YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelGIAYLFISHD 523
Cdd:TIGR01257 1045 MLEDTGL---HHKRneEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRS--GRTIIMSTHH 1119
                          250       260
                   ....*....|....*....|....
gi 949724212   524 MAVVERISHRVAVMYLGQIVEIGT 547
Cdd:TIGR01257 1120 MDEADLLGDRIAIISQGRLYCSGT 1143
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
343-556 3.55e-09

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 57.64  E-value: 3.55e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 343 VSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQrGEIIFNGQRIDTLAASKLQplRRDIQFIFQDPYASLDPRqtvgY 422
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPGS-GSIQFAGQPLEAWSAAELA--RHRAYLSQQQTPPFAMPV----F 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 423 SILEpLRVHGLLQGDAGSKRVAWLLERVGLLPEHAwRYPHEFSGGQRQRICIARAL-----ALNP--KVIIADESVSALD 495
Cdd:PRK03695  88 QYLT-LHQPDKTRTEAVASALNEVAEALGLDDKLG-RSVNQLSGGEWQRVRLAAVVlqvwpDINPagQLLLLDEPMNSLD 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 496 VSIRG---QIINLMLdlqrELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFENPQ 556
Cdd:PRK03695 166 VAQQAaldRLLSELC----QQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPEN 225
hmuV PRK13547
heme ABC transporter ATP-binding protein;
32-262 4.15e-09

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 57.91  E-value: 4.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSVtalslmhLIEQAGGEVSCDEMLLRRRNRQVIELGEQSASQMRHVRGADIAMIFQ 111
Cdd:PRK13547  17 LRDLSLRIEPGRVTALLGRNGAGKST-------LLKALAGDLTGGGAPRGARVTGDVTLNGEPLAAIDAPRLARLRAVLP 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 EPMTSLNPvFTVGEQIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALS------- 184
Cdd:PRK13547  90 QAAQPAFA-FSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAqlwpphd 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 185 --CRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFhAPQH 262
Cdd:PRK13547 169 aaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVL-TPAH 247
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
34-228 5.24e-09

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 57.03  E-value: 5.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  34 NLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrNRQVIELGEQSASQmrhvrgaDIAMIFQEP 113
Cdd:PRK10247  25 NISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFE-------GEDISTLKPEIYRQ-------QVSYCAQTP 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 114 MtslnpVF--TVGEQIAESIRLHQGASHEEAMVeakRMLDQVRIPEAkaILSRYPHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:PRK10247  91 T-----LFgdTVYDNLIFPWQIRNQQPDPAIFL---DDLERFALPDT--ILTKNIAELSGGEKQRISLIRNLQFMPKVLL 160
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHD 228
Cdd:PRK10247 161 LDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197
PLN03232 PLN03232
ABC transporter C family member; Provisional
35-283 5.61e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 59.60  E-value: 5.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   35 LSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEMllrrrnrQVIELGeqsASQMRHVrgadIAMIFQEPM 114
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDC-------DVAKFG---LTDLRRV----LSIIPQSPV 1320
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  115 TSLNPVFTVGEQIAEsirlHQGASHEEAMVEAkrmldqvripEAKAILSRYPHQL-----------SGGMRQRVMIAMAL 183
Cdd:PLN03232 1321 LFSGTVRFNIDPFSE----HNDADLWEALERA----------HIKDVIDRNPFGLdaevseggenfSVGQRQLLSLARAL 1386
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  184 SCRPAVLIADEPTTALDVTIQAQILQLIKvlQQDMSMGVIFITHDMGVVADiADRVLVMYQGEAVETGSVEQIFHAPqhp 263
Cdd:PLN03232 1387 LRRSKILVLDEATASVDVRTDSLIQRTIR--EEFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRD--- 1460
                         250       260
                  ....*....|....*....|
gi 949724212  264 yTKALLAAVPQLGAMNGHEL 283
Cdd:PLN03232 1461 -TSAFFRMVHSTGPANAQYL 1479
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
13-254 6.36e-09

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 57.00  E-value: 6.36e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMhlieqagG----EVSCDEMLLRRRNrqVI 88
Cdd:COG0396    1 LEIKNLHVSVEGKE----ILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLM-------GhpkyEVTSGSILLDGED--IL 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELG-EQSAsqmrhvrGADIAMIFQepmtslNPV----FTVGE--QIAESIRLHQGASHEEAMVEAKRMLDQVRIPEAkaI 161
Cdd:COG0396   68 ELSpDERA-------RAGIFLAFQ------YPVeipgVSVSNflRTALNARRGEELSAREFLKLLKEKMKELGLDED--F 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 162 LSRYPHQ-LSGGMRQRVMIAMALSCRPAVLIADEPTTALDV-TIQAQILQLIKVLQQDmsMGVIFITH-----DMGVvad 234
Cdd:COG0396  133 LDRYVNEgFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIdALRIVAEGVNKLRSPD--RGILIITHyqrilDYIK--- 207
                        250       260
                 ....*....|....*....|
gi 949724212 235 iADRVLVMYQGEAVETGSVE 254
Cdd:COG0396  208 -PDFVHVLVDGRIVKSGGKE 226
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
342-543 6.60e-09

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 56.12  E-value: 6.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTTGRALLRLVE---SQRGEIIFNGQRIDTLAasklQPLRRDIQFIFQDP--YASLDP 416
Cdd:cd03233   25 DFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEgnvSVEGDIHYNGIPYKEFA----EKYPGEIIYVSEEDvhFPTLTV 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVGYSIleplrvhgLLQGDAGSKRVawllervgllpehawryphefSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:cd03233  101 RETLDFAL--------RCKGNEFVRGI---------------------SGGERKRVSIAEALVSRASVLCWDNSTRGLDS 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 949724212 497 SIRGQIINLMLDLQRELGIAyLFISHDMAVVErISH---RVAVMYLGQIV 543
Cdd:cd03233  152 STALEILKCIRTMADVLKTT-TFVSLYQASDE-IYDlfdKVLVLYEGRQI 199
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
39-261 7.16e-09

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 57.03  E-value: 7.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  39 LKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrrrnrqvielgeqsasqmrhvrGADIAMIFQEPMTsLN 118
Cdd:cd03237   22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDI-----------------------------EIELDTVSYKPQY-IK 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 119 PVF--TVGEQIAESIRLHQGASHEEAMVEAKRMLDQvripeakaILSRYPHQLSGGMRQRVMIAMALScRPA-VLIADEP 195
Cdd:cd03237   72 ADYegTVRDLLSSITKDFYTHPYFKTEIAKPLQIEQ--------ILDREVPELSGGELQRVAIAACLS-KDAdIYLLDEP 142
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 196 TTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVmYQGEAvetgSVEQIFHAPQ 261
Cdd:cd03237  143 SAYLDVEQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV-FEGEP----SVNGVANPPQ 203
oligo_HPY TIGR01727
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...
541-590 1.01e-08

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 213647 [Multi-domain]  Cd Length: 87  Bit Score: 52.75  E-value: 1.01e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 949724212  541 QIVEIGTRRAVFENPQHPYTRKLMAAVPVADpshhRPQRVLLSddIPSNI 590
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIK----KRDRKLIS--IPGEV 44
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
29-266 1.17e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 58.50  E-value: 1.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   29 VSAVRNLSFRLKRGETLAIVGESGSGKSvTALSLM---------HLI---EQAGGEVSCDEMLLRRRNRQVIELGEQSAS 96
Cdd:PTZ00265 1181 VPIYKDLTFSCDSKKTTAIVGETGSGKS-TVMSLLmrfydlkndHHIvfkNEHTNDMTNEQDYQGDEEQNVGMKNVNEFS 1259
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   97 QMRHVRGADIAMIFQEP--------------MTSLNPVFTVGEQ--------IAESIRLhqgaSHEEAMVE-AKRMLDQV 153
Cdd:PTZ00265 1260 LTKEGGSGEDSTVFKNSgkilldgvdicdynLKDLRNLFSIVSQepmlfnmsIYENIKF----GKEDATREdVKRACKFA 1335
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  154 RIPEAKAILSR--------YPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFI 225
Cdd:PTZ00265 1336 AIDEFIESLPNkydtnvgpYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITI 1415
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 949724212  226 TH--------DMGVVADIADRVLVMYQGEavetGSVEQIFHAPQHPYTK 266
Cdd:PTZ00265 1416 AHriasikrsDKIVVFNNPDRTGSFVQAH----GTHEELLSVQDGVYKK 1460
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
33-211 1.31e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 55.27  E-value: 1.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrQVIELGEqSASQMRHVRGADiAMifqe 112
Cdd:PRK13539  19 SGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDG--------GDIDDPD-VAEACHYLGHRN-AM---- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 113 pmtslNPVFTVGEQIAESIRLHQGasHEEAMVEAkrmLDQVRIPEAKAILSRYphqLSGGMRQRVMIA-MALSCRPaVLI 191
Cdd:PRK13539  85 -----KPALTVAENLEFWAAFLGG--EELDIAAA---LEAVGLAPLAHLPFGY---LSAGQKRRVALArLLVSNRP-IWI 150
                        170       180
                 ....*....|....*....|
gi 949724212 192 ADEPTTALDVTIQAQILQLI 211
Cdd:PRK13539 151 LDEPTAALDAAAVALFAELI 170
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
35-239 1.46e-08

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 55.19  E-value: 1.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  35 LSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVScdemllrrrnrqvieLGEQSASQMRHVRGADIAMIFQEPm 114
Cdd:cd03231   19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVL---------------LNGGPLDFQRDSIARGLLYLGHAP- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 115 tSLNPVFTVGEQIAESIRLHQGASHEEAmveakrmLDQVRIpeaKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADE 194
Cdd:cd03231   83 -GIKTTLSVLENLRFWHADHSDEQVEEA-------LARVGL---NGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDE 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 949724212 195 PTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRV 239
Cdd:cd03231  152 PTTALDKAGVARFAEAMAGHCARGGMVVLTTHQDLGLSEAGAREL 196
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
341-532 1.47e-08

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 53.99  E-value: 1.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTtgraLLRLVesqrgeiifngqridtlaASKLQPLRRDIQfifqdpyasLDPRQTV 420
Cdd:cd03221   17 KDISLTINPGDRIGLVGRNGAGKST----LLKLI------------------AGELEPDEGIVT---------WGSTVKI 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 421 GYsileplrvhgllqgdagskrvawllervgllpehawrYPHeFSGGQRQRICIARALALNPKVIIADESVSALDVSIRG 500
Cdd:cd03221   66 GY-------------------------------------FEQ-LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIE 107
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 949724212 501 QIINLMLDLQRelgiAYLFISHDM----AVVERISH 532
Cdd:cd03221  108 ALEEALKEYPG----TVILVSHDRyfldQVATKIIE 139
ycf16 CHL00131
sulfate ABC transporter protein; Validated
312-547 1.49e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 55.80  E-value: 1.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 312 PILRVRNLVTRfplrsgilnrvTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRAL-----LRLVEsqrGEIIFNGQ 386
Cdd:CHL00131   6 PILEIKNLHAS-----------VNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIaghpaYKILE---GDILFKGE 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 387 RIDTLAASklQPLRRDIQFIFQDPY------------ASLDPRQT-VGYSILEPLRVHGLLQgdagSKrvawlLERVGLL 453
Cdd:CHL00131  72 SILDLEPE--ERAHLGIFLAFQYPIeipgvsnadflrLAYNSKRKfQGLPELDPLEFLEIIN----EK-----LKLVGMD 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 454 PEHAWRYPHE-FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQI---INLMLDLQRelgiAYLFISHDMAVVER 529
Cdd:CHL00131 141 PSFLSRNVNEgFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIaegINKLMTSEN----SIILITHYQRLLDY 216
                        250
                 ....*....|....*....
gi 949724212 530 IS-HRVAVMYLGQIVEIGT 547
Cdd:CHL00131 217 IKpDYVHVMQNGKIIKTGD 235
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
13-252 1.50e-08

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 58.10  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    13 LAVSNLNIAFEQEQQrvSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGevscdemllrrrnrQVIELGE 92
Cdd:TIGR01257  929 VCVKNLVKIFEPSGR--PAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSG--------------TVLVGGK 992
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    93 QSASQMRHVRGAdIAMIFQEpmtslNPVF---TVGEQIAESIRLhQGASHEEAMVEAKRMLDQVRIPEAKailSRYPHQL 169
Cdd:TIGR01257  993 DIETNLDAVRQS-LGMCPQH-----NILFhhlTVAEHILFYAQL-KGRSWEEAQLEMEAMLEDTGLHHKR---NEEAQDL 1062
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIkvLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVE 249
Cdd:TIGR01257 1063 SGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYC 1140

                   ...
gi 949724212   250 TGS 252
Cdd:TIGR01257 1141 SGT 1143
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
304-553 2.01e-08

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 57.42  E-value: 2.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 304 QDTVVEGEpilRVRNLVTR---------FPLRSGilnRVtrevhAVENVSFDLWPGET--------------LSLVGESG 360
Cdd:PRK10790 309 QQAVVAGE---RVFELMDGprqqygnddRPLQSG---RI-----DIDNVSFAYRDDNLvlqninlsvpsrgfVALVGHTG 377
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 361 CGKSTTGRALLRLVESQRGEIIFNGQRIDTLAAsklQPLRRDIQFIFQDPY---ASLDPRQTVGYSILEplrvhgllqgd 437
Cdd:PRK10790 378 SGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSH---SVLRQGVAMVQQDPVvlaDTFLANVTLGRDISE----------- 443
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 438 agsKRVAWLLERVGL------LPEHAWRYPHE----FSGGQRQRICIARALALNPKVIIADESVSALDvSIRGQIINLML 507
Cdd:PRK10790 444 ---EQVWQALETVQLaelarsLPDGLYTPLGEqgnnLSVGQKQLLALARVLVQTPQILILDEATANID-SGTEQAIQQAL 519
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 508 DLQRElgiaylfisHDMAVVerISHRVA---------VMYLGQIVEIGTRRAVFE 553
Cdd:PRK10790 520 AAVRE---------HTTLVV--IAHRLStiveadtilVLHRGQAVEQGTHQQLLA 563
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
336-554 2.31e-08

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 55.27  E-value: 2.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLqpLRRDIQFIFQDpyASLD 415
Cdd:PRK11614  17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKI--MREAVAIVPEG--RRVF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGysilEPLRVHGLL-QGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK11614  93 SRMTVE----ENLAMGGFFaERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGL 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 495 DVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFEN 554
Cdd:PRK11614 169 APIIIQQIFDTIEQL-REQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLAN 227
PTZ00243 PTZ00243
ABC transporter; Provisional
32-261 2.84e-08

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 57.10  E-value: 2.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   32 VRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllRRRNRQVIELGeqsasqMRHVRgADIAMIFQ 111
Cdd:PTZ00243 1326 LRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEI-------RVNGREIGAYG------LRELR-RQFSMIPQ 1391
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  112 EPMtslnpVF--TVGEQIAESIRlhqgASHEE--AMVEAKRMLDQVrIPEAKAILSRYPH---QLSGGMRQRVMIAMALS 184
Cdd:PTZ00243 1392 DPV-----LFdgTVRQNVDPFLE----ASSAEvwAALELVGLRERV-ASESEGIDSRVLEggsNYSVGQRQLMCMARALL 1461
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  185 CRPAVLI-ADEPTT----ALDVTIQAQILQLIKvlqqdmSMGVIFITHDMGVVADIaDRVLVMYQGEAVETGSVEQIFHA 259
Cdd:PTZ00243 1462 KKGSGFIlMDEATAnidpALDRQIQATVMSAFS------AYTVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPRELVMN 1534

                  ..
gi 949724212  260 PQ 261
Cdd:PTZ00243 1535 RQ 1536
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
341-528 2.90e-08

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 54.42  E-value: 2.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRrdiqfifqdpYASLDPRQTV 420
Cdd:cd03231   17 SGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLL----------YLGHAPGIKT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 421 GYSILEPLRVHGLLQGDAGskrVAWLLERVGLLP-EHawRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR 499
Cdd:cd03231   87 TLSVLENLRFWHADHSDEQ---VEEALARVGLNGfED--RPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGV 161
                        170       180
                 ....*....|....*....|....*....
gi 949724212 500 GQIINLMLDLQRELGIAYLFISHDMAVVE 528
Cdd:cd03231  162 ARFAEAMAGHCARGGMVVLTTHQDLGLSE 190
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
341-506 3.08e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 54.11  E-value: 3.08e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaasklqplrrDIQFIFQDPYAS----LDP 416
Cdd:PRK13539  19 SGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDID------------DPDVAEACHYLGhrnaMKP 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVgysiLEPLRVHGLLQGDAGSkRVAWLLERVGLLP-EHawRYPHEFSGGQRQRICIARALALNPKVIIADESVSALD 495
Cdd:PRK13539  87 ALTV----AENLEFWAAFLGGEEL-DIAAALEAVGLAPlAH--LPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALD 159
                        170
                 ....*....|.
gi 949724212 496 VSIRGQIINLM 506
Cdd:PRK13539 160 AAAVALFAELI 170
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
341-541 3.53e-08

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 54.04  E-value: 3.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTtgraLLR----LVESQRGEIIFNGQRIDTLAASklqpLRRDIQFIFQdpYASLDP 416
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGKTS----LLRilagLARPDAGEVLWQGEPIRRQRDE----YHQDLLYLGH--QPGIKT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 417 RQTVgysiLEPLRVHGLLQGDAGSKRVAWLLERVGLLP-EHAwryP-HEFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:PRK13538  88 ELTA----LENLRFYQRLHGPGDDEALWEALAQVGLAGfEDV---PvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAI 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 949724212 495 DVSIRGQIINLMLDLQRELGIAYLFISHDMavvERISHRVAVMYLGQ 541
Cdd:PRK13538 161 DKQGVARLEALLAQHAEQGGMVILTTHQDL---PVASDKVRKLRLGQ 204
PLN03211 PLN03211
ABC transporter G-25; Provisional
349-497 4.25e-08

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 56.43  E-value: 4.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 349 PGETLSLVGESGCGKSTTGRALLRLVESQ--RGEIIFNGQRIDtlaasklQPLRRDIQFIFQDP--YASLDPRQTVGYSI 424
Cdd:PLN03211  93 PGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPT-------KQILKRTGFVTQDDilYPHLTVRETLVFCS 165
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 425 LepLRVHGLLQGDAGSKRVAWLLERVGLLPEHAWRYPHEF----SGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PLN03211 166 L--LRLPKSLTKQEKILVAESVISELGLTKCENTIIGNSFirgiSGGERKRVSIAHEMLINPSLLILDEPTSGLDAT 240
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
11-260 4.48e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 56.58  E-value: 4.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   11 DVLAVSNLNIAFEQEQQR-VSAVRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEQ--------------------- 68
Cdd:PTZ00265  379 DIKKIQFKNVRFHYDTRKdVEIYKDLNFTLTEGKTYAFVGESGCGKS----TILKLIERlydptegdiiindshnlkdin 454
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   69 ------AGGEVSCDEMLLRRRNRQVI---------------ELGE-----QSASQMRHVRGADIAMIFQEPMTSlnpvfT 122
Cdd:PTZ00265  455 lkwwrsKIGVVSQDPLLFSNSIKNNIkyslyslkdlealsnYYNEdgndsQENKNKRNSCRAKCAGDLNDMSNT-----T 529
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  123 VGEQIAESIRLHQGASHEEAMVEAKRML--DQVR-IPEA-KAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTA 198
Cdd:PTZ00265  530 DSNELIEMRKNYQTIKDSEVVDVSKKVLihDFVSaLPDKyETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSS 609
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212  199 LDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVAdIADRVLVMYQGEAVETGSVEQIFHAP 260
Cdd:PTZ00265  610 LDNKSEYLVQKTINNLKGNENRITIIIAHRLSTIR-YANTIFVLSNRERGSTVDVDIIGEDP 670
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
34-531 4.75e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 56.10  E-value: 4.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   34 NLSFRlkRGETLAIVGESGSGKSvTALSLMHLIEQA-GGEVSCDE-----MLLRR----RNRQVIELGEQSASQMRHV-- 101
Cdd:TIGR03719  25 SLSFF--PGAKIGVLGLNGAGKS-TLLRIMAGVDKDfNGEARPQPgikvgYLPQEpqldPTKTVRENVEEGVAEIKDAld 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  102 RGADIAMIFQEPMTSLNPVFTVGEQIAESIRlHQGASHEEAMVEakRMLDQVRIPEAKAILSRyphqLSGGMRQRVMIAM 181
Cdd:TIGR03719 102 RFNEISAKYAEPDADFDKLAAEQAELQEIID-AADAWDLDSQLE--IAMDALRCPPWDADVTK----LSGGERRRVALCR 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  182 ALSCRPAVLIADEPTTALDVTIQAQILQLIkvlqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVE-----TGSVEQ- 255
Cdd:TIGR03719 175 LLLSKPDMLLLDEPTNHLDAESVAWLERHL----QEYPGTVVAVTHDRYFLDNVAGWILELDRGRGIPwegnySSWLEQk 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  256 ------------------------IFHAP--QHPYTKALLAAVPQlgaMNGHELPRRFPLISLHDPshVEPQTeqdtvve 309
Cdd:TIGR03719 251 qkrleqeekeesarqktlkrelewVRQSPkgRQAKSKARLARYEE---LLSQEFQKRNETAEIYIP--PGPRL------- 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  310 GEPILRVRNLVTRFPLRsgILnrvtrevhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNgqriD 389
Cdd:TIGR03719 319 GDKVIEAENLTKAFGDK--LL---------IDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG----E 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  390 TLAASKLQPLRrdiqfifqdpyASLDPRQTVGYSILEplrvhGLLQGDAGSKRV---AWL----------LERVGLLpeh 456
Cdd:TIGR03719 384 TVKLAYVDQSR-----------DALDPNKTVWEEISG-----GLDIIKLGKREIpsrAYVgrfnfkgsdqQKKVGQL--- 444
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212  457 awryphefSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQrelGIAyLFISHDMAVVERIS 531
Cdd:TIGR03719 445 --------SGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVETLRALEEALLNFA---GCA-VVISHDRWFLDRIA 507
oligo_HPY pfam08352
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...
248-277 6.18e-08

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.


Pssm-ID: 400588 [Multi-domain]  Cd Length: 65  Bit Score: 49.71  E-value: 6.18e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 949724212  248 VETGSVEQIFHAPQHPYTKALLAAVPQLGA 277
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDP 30
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
170-523 6.26e-08

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 55.56  E-value: 6.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTiqaQILQLIKVLqQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVE 249
Cdd:PRK10636 151 SGGWRMRLNLAQALICRSDLLLLDEPTNHLDLD---AVIWLEKWL-KSYQGTLILISHDRDFLDPIVDKIIHIEQQSLFE 226
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 250 -TGSV----------------------EQIFHApQHPYTKALLAAVPQLGAMNGHELPRRFPLISlhdPSHV-------- 298
Cdd:PRK10636 227 yTGNYssfevqratrlaqqqamyesqqERVAHL-QSYIDRFRAKATKAKQAQSRIKMLERMELIA---PAHVdnpfhfsf 302
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 299 -EPQTEQDtvvegePILRVRNlvtrfpLRSGILNRVTrevhaVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQ 377
Cdd:PRK10636 303 rAPESLPN------PLLKMEK------VSAGYGDRII-----LDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPV 365
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 378 RGEI-IFNGQRIDTLAASKLQPLRRD---IQFIfqdpyASLDPRQTVgysilEPLR--VHGL-LQGDagskRVAWLLERv 450
Cdd:PRK10636 366 SGEIgLAKGIKLGYFAQHQLEFLRADespLQHL-----ARLAPQELE-----QKLRdyLGGFgFQGD----KVTEETRR- 430
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 451 gllpehawrypheFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelgiAYLFISHD 523
Cdd:PRK10636 431 -------------FSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEG----ALVVVSHD 486
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
41-246 7.06e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 51.99  E-value: 7.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    41 RGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrrrnrqvielgeqsasqmrhvrgadiamifqepmtslnpv 120
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV----------------------------------------------- 33
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   121 ftvgeqiaesirlhqgasheeAMVEAKRMLDQVRIPEAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALD 200
Cdd:smart00382  34 ---------------------IYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLD 92
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212   201 VTIQAQILQLI-----KVLQQDMSMGVIFITHDM-----GVVADIADRVLVMYQGE 246
Cdd:smart00382  93 AEQEALLLLLEelrllLLLKSEKNLTVILTTNDEkdlgpALLRRRFDRRIVLLLIL 148
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
460-536 7.35e-08

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 55.81  E-value: 7.35e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212  460 YPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAV 536
Cdd:PTZ00265 1355 YGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIKR-SDKIVV 1430
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
316-507 1.11e-07

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 53.70  E-value: 1.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 316 VRNLVTRFplrsgilnrvTREVHAV-ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQrGEIIFNGQRIDTLAas 394
Cdd:cd03289    5 VKDLTAKY----------TEGGNAVlENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDGVSWNSVP-- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 395 kLQPLRRDIQ------FIFQDPY-ASLDPRQTvgYSILEPLRVhgllQGDAGSKRVA--------WLLERVGLLPEHawr 459
Cdd:cd03289   72 -LQKWRKAFGvipqkvFIFSGTFrKNLDPYGK--WSDEEIWKV----AEEVGLKSVIeqfpgqldFVLVDGGCVLSH--- 141
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 949724212 460 yphefsgGQRQRICIARALALNPKVIIADESVSALDvSIRGQIINLML 507
Cdd:cd03289  142 -------GHKQLMCLARSVLSKAKILLLDEPSAHLD-PITYQVIRKTL 181
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
298-553 1.29e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 54.95  E-value: 1.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   298 VEPQT-EQDTVVEGEPilrvrNLVTrfpLRSGILNRVTREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVES 376
Cdd:TIGR00957  619 LEPDSiERRTIKPGEG-----NSIT---VHNATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDK 690
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   377 QRGEIIFNGQRIDTLAASKLQ--PLRRDIQFIFQdpyasldprqtvgysiLEPLRVHGLLQGDAgskrvawLLERVGLLP 454
Cdd:TIGR00957  691 VEGHVHMKGSVAYVPQQAWIQndSLRENILFGKA----------------LNEKYYQQVLEACA-------LLPDLEILP 747
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   455 EHAWRYPHE----FSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQREL-GIAYLFISHDMAVVER 529
Cdd:TIGR00957  748 SGDRTEIGEkgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVIGPEGVLkNKTRILVTHGISYLPQ 827
                          250       260
                   ....*....|....*....|....
gi 949724212   530 ISHrVAVMYLGQIVEIGTRRAVFE 553
Cdd:TIGR00957  828 VDV-IIVMSGGKISEMGSYQELLQ 850
PLN03211 PLN03211
ABC transporter G-25; Provisional
42-251 1.47e-07

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 54.50  E-value: 1.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  42 GETLAIVGESGSGKSVTALSLMHLIEQAG--GEVSCDEmllRRRNRQVIElgeqsasqmrhvrgaDIAMIFQEPMtsLNP 119
Cdd:PLN03211  94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANN---RKPTKQILK---------------RTGFVTQDDI--LYP 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 120 VFTVGEQI--AESIRLHQGASHEEAMVEAKRMLDQVRIP--EAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEP 195
Cdd:PLN03211 154 HLTVRETLvfCSLLRLPKSLTKQEKILVAESVISELGLTkcENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEP 233
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 196 TTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYQGEAVETG 251
Cdd:PLN03211 234 TSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFG 289
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
340-522 1.77e-07

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 51.87  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQplrrdiQFIFQDPYASLDPRQT 419
Cdd:PRK13540  17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQK------QLCFVGHRSGINPYLT 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 420 vgysilepLRVHGL--LQGDAGSKRVAWLLERVGLlpEHAWRYP-HEFSGGQRQRICIARALALNPKVIIADESVSALDv 496
Cdd:PRK13540  91 --------LRENCLydIHFSPGAVGITELCRLFSL--EHLIDYPcGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD- 159
                        170       180
                 ....*....|....*....|....*.
gi 949724212 497 SIRGQIINLMLDLQRELGIAYLFISH 522
Cdd:PRK13540 160 ELSLLTIITKIQEHRAKGGAVLLTSH 185
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
339-550 3.20e-07

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 53.44  E-value: 3.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 339 AVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDtlaASKLQPLRRDIQFIFQDpyasldprq 418
Cdd:PRK10522 338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVT---AEQPEDYRKLFSAVFTD--------- 405
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 419 tvgysileplrVH--GLLQGDAG----SKRVAWLLERVGL---LPEHAWRYPH-EFSGGQRQRICIARALALNPKVIIAD 488
Cdd:PRK10522 406 -----------FHlfDQLLGPEGkpanPALVEKWLERLKMahkLELEDGRISNlKLSKGQKKRLALLLALAEERDILLLD 474
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 489 ESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDMAVVERiSHRVAVMYLGQIVEI-GTRRA 550
Cdd:PRK10522 475 EWAADQDPHFRREFYQVLLPLLQEMGKTIFAISHDDHYFIH-ADRLLEMRNGQLSELtGEERD 536
GguA NF040905
sugar ABC transporter ATP-binding protein;
12-248 7.47e-07

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.10  E-value: 7.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQQRVsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLM-----HLIeqaGGEVSCDEMLLRRRN-R 85
Cdd:NF040905 257 VFEVKNWTVYHPLHPERK-VVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFgrsygRNI---SGTVFKDGKEVDVSTvS 332
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  86 QVIELGEQSASQMRHVRGadiamifqepmtsLNpvftVGEQIAESIRL--HQGAS-------HEEAMVeAKRMLDQVRIP 156
Cdd:NF040905 333 DAIDAGLAYVTEDRKGYG-------------LN----LIDDIKRNITLanLGKVSrrgvideNEEIKV-AEEYRKKMNIK 394
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 157 ----EAKAIlsryphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHDMGVV 232
Cdd:NF040905 395 tpsvFQKVG------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINEL-AAEGKGVIVISSELPEL 467
                        250
                 ....*....|....*.
gi 949724212 233 ADIADRVLVMYQGEAV 248
Cdd:NF040905 468 LGMCDRIYVMNEGRIT 483
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
141-243 9.08e-07

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 49.28  E-value: 9.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 141 EAMVEAKRMLDQVRIPEAKAILSRYP--HQLSGGMRQRVMIAMAL---SCRPAVLIA-DEPTTALDVTIQAQILQLIKVL 214
Cdd:cd03227   48 AQSATRRRSGVKAGCIVAAVSAELIFtrLQLSGGEKELSALALILalaSLKPRPLYIlDEIDRGLDPRDGQALAEAILEH 127
                         90       100
                 ....*....|....*....|....*....
gi 949724212 215 QQDMSMgVIFITHDMGvVADIADRVLVMY 243
Cdd:cd03227  128 LVKGAQ-VIVITHLPE-LAELADKLIHIK 154
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
341-543 9.72e-07

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 51.87  E-value: 9.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQridtLAASKLQplrrdiqfifQDPyasldPRQTV 420
Cdd:PRK11147  20 DNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQD----LIVARLQ----------QDP-----PRNVE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 421 G------------------------------YS---------ILEPLRVHGLLQGDAgskRVAWLLERVGLLPEHAWRyp 461
Cdd:PRK11147  81 GtvydfvaegieeqaeylkryhdishlvetdPSeknlnelakLQEQLDHHNLWQLEN---RINEVLAQLGLDPDAALS-- 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 462 hEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRelgiAYLFISHDMAVVERISHRVAVMYLGQ 541
Cdd:PRK11147 156 -SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQG----SIIFISHDRSFIRNMATRIVDLDRGK 230

                 ..
gi 949724212 542 IV 543
Cdd:PRK11147 231 LV 232
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
340-503 1.04e-06

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 52.22  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   340 VENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVeSQRGEIIFNGQRIDTLAaskLQPLRRDIQ------FIFQDPY-A 412
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLL-STEGEIQIDGVSWNSVT---LQTWRKAFGvipqkvFIFSGTFrK 1310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   413 SLDPRQTvgYSILEPLRVhgllQGDAGSKRVA--------WLLERVGLLpehawrypheFSGGQRQRICIARALALNPKV 484
Cdd:TIGR01271 1311 NLDPYEQ--WSDEEIWKV----AEEVGLKSVIeqfpdkldFVLVDGGYV----------LSNGHKQLMCLARSILSKAKI 1374
                          170
                   ....*....|....*....
gi 949724212   485 IIADESVSALDvSIRGQII 503
Cdd:TIGR01271 1375 LLLDEPSAHLD-PVTLQII 1392
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
32-256 1.13e-06

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 50.63  E-value: 1.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  32 VRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEqagGEVSCDEMLLRRRNRqvIELGEQSASQMrhvrgadiamifq 111
Cdd:cd03291   53 LKNINLKIEKGEMLAITGSTGSGKT----SLLMLIL---GELEPSEGKIKHSGR--ISFSSQFSWIM------------- 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 112 ePMTslnpvftvgeqIAESIRLhqGASHEE----AMVEAKRM-LDQVRIPEA-KAILSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:cd03291  111 -PGT-----------IKENIIF--GVSYDEyrykSVVKACQLeEDITKFPEKdNTVLGEGGITLSGGQRARISLARAVYK 176
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 186 RPAVLIADEPTTALDVTIQAQILQ--LIKVLQQDMSmgvIFITHDMGVVAdIADRVLVMYQGEAVETGSVEQI 256
Cdd:cd03291  177 DADLYLLDSPFGYLDVFTEKEIFEscVCKLMANKTR---ILVTSKMEHLK-KADKILILHEGSSYFYGTFSEL 245
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
157-243 1.17e-06

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 50.44  E-value: 1.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 157 EAKAILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIA 236
Cdd:cd03236  128 ELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLIRELAED-DNYVLVVEHDLAVLDYLS 206

                 ....*..
gi 949724212 237 DRVLVMY 243
Cdd:cd03236  207 DYIHCLY 213
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
161-246 1.26e-06

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 51.35  E-value: 1.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 161 ILSRYPHQLSGGMRQRVMIAMALScRPAVL-IADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRV 239
Cdd:PRK13409 446 LLDKNVKDLSGGELQRVAIAACLS-RDADLyLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDIYMIDYISDRL 524

                 ....*..
gi 949724212 240 LVmYQGE 246
Cdd:PRK13409 525 MV-FEGE 530
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
13-240 1.34e-06

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 51.43  E-value: 1.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrNRQVIELGE 92
Cdd:PRK15064 320 LEVENLTKGFDNGP----LFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSE------NANIGYYAQ 389
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQmrhvrgadiamiFQEPMTslnpVFtvgeqiaESIRLHQGASHEEAMVEAK--RML---DQVRIPeAKAilsryph 167
Cdd:PRK15064 390 DHAYD------------FENDLT----LF-------DWMSQWRQEGDDEQAVRGTlgRLLfsqDDIKKS-VKV------- 438
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 168 qLSGGMRQRVMIAMALSCRPAVLIADEPTTALDV-TIQAQILQLikvlqqDMSMG-VIFITHDMGVVADIADRVL 240
Cdd:PRK15064 439 -LSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMeSIESLNMAL------EKYEGtLIFVSHDREFVSSLATRII 506
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
342-495 2.00e-06

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 48.78  E-value: 2.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 342 NVSFDLWPGETLSLVGESGCGKSTtgraLLRlVESQR-------GEIIFNGQRIDtlaasklQPLRRDIQFIFQDPyaSL 414
Cdd:cd03232   25 NISGYVKPGTLTALMGESGAGKTT----LLD-VLAGRktagvitGEILINGRPLD-------KNFQRSTGYVEQQD--VH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DPRQTVgysiLEPLRVHGLLQGdagskrvawllervgllpehawrypheFSGGQRQRICIARALALNPKVIIADESVSAL 494
Cdd:cd03232   91 SPNLTV----REALRFSALLRG---------------------------LSVEQRKRLTIGVELAAKPSILFLDEPTSGL 139

                 .
gi 949724212 495 D 495
Cdd:cd03232  140 D 140
PLN03130 PLN03130
ABC transporter C family member; Provisional
35-256 2.61e-06

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 50.89  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   35 LSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDEmllrrrnrqvIELGEQSASQMRHVRGadiaMIFQepm 114
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDG----------CDISKFGLMDLRKVLG----IIPQ--- 1320
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  115 tslNPVFTVGeqiaeSIRL-------HQGASHEEAMvEAKRMLDQVRIPEA--KAILSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:PLN03130 1321 ---APVLFSG-----TVRFnldpfneHNDADLWESL-ERAHLKDVIRRNSLglDAEVSEAGENFSVGQRQLLSLARALLR 1391
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212  186 RPAVLIADEPTTALDVTIQAQILQLIKvlQQDMSMGVIFITHDMGVVADiADRVLVMYQGEAVETGSVEQI 256
Cdd:PLN03130 1392 RSKILVLDEATAAVDVRTDALIQKTIR--EEFKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENL 1459
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
341-504 2.69e-06

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 48.62  E-value: 2.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 341 ENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGqridTLAASKLQP------LRRDIqfIFQDPYasl 414
Cdd:cd03250   22 KDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG----SIAYVSQEPwiqngtIRENI--LFGKPF--- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DP---RQTVGYSILEP-LRVhgLLQGDA---GSKRVAwllervgllpehawrypheFSGGQRQRICIARALALNPKVIIA 487
Cdd:cd03250   93 DEeryEKVIKACALEPdLEI--LPDGDLteiGEKGIN-------------------LSGGQKQRISLARAVYSDADIYLL 151
                        170
                 ....*....|....*..
gi 949724212 488 DESVSALDVSIRGQIIN 504
Cdd:cd03250  152 DDPLSAVDAHVGRHIFE 168
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
336-546 3.15e-06

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 49.73  E-value: 3.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLWPGETLSLVGESGCGKSTtGRALLRLVESQRGEiifNGQRIDTLAASKlQPLRRDIqfifqDPYASLD 415
Cdd:NF000106  25 EVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGR---RPWRF*TWCANR-RALRRTI-----G*HRPVR 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 416 PRQTVGYSILEPLRVHG----LLQGDAGSkRVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESV 491
Cdd:NF000106  95 *GRRESFSGRENLYMIGr*ldLSRKDARA-RADELLERFSL-TEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPT 172
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 492 SALDVSIRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Cdd:NF000106 173 TGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADG 226
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
344-587 3.73e-06

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 49.63  E-value: 3.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 344 SFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQPLRRDIqfiFQDPYASL------DPR 417
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKLVSDE---WQRNNTDMlspgedDTG 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGYSILEPLRVHGLLQGDAGSKRVAWLLERvgllpehawRYPHeFSGGQRQRICIARALALNPKVIIADESVSALDVS 497
Cdd:PRK10938 100 RTTAEIIQDEVKDPARCEQLAQQFGITALLDR---------RFKY-LSTGETRKTLLCQALMSEPDLLILDEPFDGLDVA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 498 IRGQIINLMLDLQRElGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFEN---PQHPYTRKLM-AAVPVADps 573
Cdd:PRK10938 170 SRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQQalvAQLAHSEQLEgVQLPEPD-- 246
                        250
                 ....*....|....
gi 949724212 574 hHRPQRVLLSDDIP 587
Cdd:PRK10938 247 -EPSARHALPANEP 259
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
13-265 3.74e-06

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 48.75  E-value: 3.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  13 LAVSNLNIAFEQEQQRVsaVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVSCDemllrrrnrqvielGE 92
Cdd:cd03288   20 IKIHDLCVRYENNLKPV--LKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVID--------------GI 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  93 QSASQMRHVRGADIAMIFQEPMTslnpvftvgeqIAESIRLHQGAsheEAMVEAKRMLDQVRIPEAKAILSRYPHQL--- 169
Cdd:cd03288   84 DISKLPLHTLRSRLSIILQDPIL-----------FSGSIRFNLDP---ECKCTDDRLWEALEIAQLKNMVKSLPGGLdav 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 170 --------SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQaQILQLIkVLQQDMSMGVIFITHDMGVVADiADRVLV 241
Cdd:cd03288  150 vteggenfSVGQRQLFCLARAFVRKSSILIMDEATASIDMATE-NILQKV-VMTAFADRTVVTIAHRVSTILD-ADLVLV 226
                        250       260
                 ....*....|....*....|....
gi 949724212 242 MYQGEAVETGSVEQIFHAPQHPYT 265
Cdd:cd03288  227 LSRGILVECDTPENLLAQEDGVFA 250
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
169-251 3.97e-06

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 47.70  E-value: 3.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIA--MALSCRPAVLIADEPTTALDvtiQAQILQLIKVLQQ--DMSMGVIFITHDMGVVaDIADRVLVM-- 242
Cdd:cd03238   88 LSGGELQRVKLAseLFSEPPGTLFILDEPSTGLH---QQDINQLLEVIKGliDLGNTVILIEHNLDVL-SSADWIIDFgp 163
                         90
                 ....*....|...
gi 949724212 243 ----YQGEAVETG 251
Cdd:cd03238  164 gsgkSGGKVVFSG 176
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
32-256 4.69e-06

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 49.91  E-value: 4.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    32 VRNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIEqagGEVSCDEMLLRRRNRqvIELGEQSASQMrhvrgadiamifq 111
Cdd:TIGR01271  442 LKNISFKLEKGQLLAVAGSTGSGKS----SLLMMIM---GELEPSEGKIKHSGR--ISFSPQTSWIM------------- 499
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   112 ePMTslnpvftvgeqIAESIRLhqGASHEE----AMVEAKRM-LDQVRIPEA-KAILSRYPHQLSGGMRQRVMIAMALSC 185
Cdd:TIGR01271  500 -PGT-----------IKDNIIF--GLSYDEyrytSVIKACQLeEDIALFPEKdKTVLGEGGITLSGGQRARISLARAVYK 565
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212   186 RPAVLIADEPTTALDVTIQAQILQ--LIKVLqqdMSMGVIFITHDMGVVADiADRVLVMYQGEAVETGSVEQI 256
Cdd:TIGR01271  566 DADLYLLDSPFTHLDVVTEKEIFEscLCKLM---SNKTRILVTSKLEHLKK-ADKILLLHEGVCYFYGTFSEL 634
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
349-538 5.25e-06

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 48.13  E-value: 5.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 349 PGETLSLVGESGCGKSTTGRALlrlvesqRGEIIFNGQR----------IDTLAASKLQP-----LRRDIQFIFQDPYAS 413
Cdd:cd03236   25 EGQVLGLVGPNGIGKSTALKIL-------AGKLKPNLGKfddppdwdeiLDEFRGSELQNyftklLEGDVKVIVKPQYVD 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 414 LDPRQTVGySILEPL-RVHGLLQGDAGSKRvawlLERVGLLPEHAwrypHEFSGGQRQRICIARALALNPKVIIADESVS 492
Cdd:cd03236   98 LIPKAVKG-KVGELLkKKDERGKLDELVDQ----LELRHVLDRNI----DQLSGGELQRVAIAAALARDADFYFFDEPSS 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 949724212 493 ALDVsirGQIINlMLDLQREL---GIAYLFISHDMAVVERISHRVAVMY 538
Cdd:cd03236  169 YLDI---KQRLN-AARLIRELaedDNYVLVVEHDLAVLDYLSDYIHCLY 213
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
23-262 5.65e-06

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 49.72  E-value: 5.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    23 EQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKS----VTALSLMHLIEQAGGEVSCDemllrrrnrqvielGEQSASQM 98
Cdd:TIGR00956   68 FRDTKTFDILKPMDGLIKPGELTVVLGRPGSGCStllkTIASNTDGFHIGVEGVITYD--------------GITPEEIK 133
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    99 RHVRGaDIAMIFQepmTSLN-PVFTVGEQIAESIRLH------QGASHEEamvEAKRMLDQV------RIPEAKAILSRY 165
Cdd:TIGR00956  134 KHYRG-DVVYNAE---TDVHfPHLTVGETLDFAARCKtpqnrpDGVSREE---YAKHIADVYmatyglSHTRNTKVGNDF 206
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   166 PHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDvtiQAQILQLIKVLQQDMSmgvifITHDMGVVA---------DIA 236
Cdd:TIGR00956  207 VRGVSGGERKRVSIAEASLGGAKIQCWDNATRGLD---SATALEFIRALKTSAN-----ILDTTPLVAiyqcsqdayELF 278
                          250       260
                   ....*....|....*....|....*.
gi 949724212   237 DRVLVMYQGeavetgsvEQIFHAPQH 262
Cdd:TIGR00956  279 DKVIVLYEG--------YQIYFGPAD 296
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
12-251 5.80e-06

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 48.25  E-value: 5.80e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  12 VLAVSNLNIAFEQEQqrvsAVRNLSFRLKRGETLAIVGESGSGKSVTALSLM--HLIEQAGGEVscdemllRRRNRQVIE 89
Cdd:PRK09580   1 MLSIKDLHVSVEDKA----ILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTV-------EFKGKDLLE 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  90 LGEQSASqmrhvrGADIAMIFQEPM------------TSLNPVFTVGEQiaesirlhqgasheeamvEAKRMLDQVRIPE 157
Cdd:PRK09580  70 LSPEDRA------GEGIFMAFQYPVeipgvsnqfflqTALNAVRSYRGQ------------------EPLDRFDFQDLME 125
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 158 AKAILSRYPHQL---------SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLqQDMSMGVIFITHD 228
Cdd:PRK09580 126 EKIALLKMPEDLltrsvnvgfSGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSL-RDGKRSFIIVTHY 204
                        250       260
                 ....*....|....*....|....
gi 949724212 229 MGVVADIA-DRVLVMYQGEAVETG 251
Cdd:PRK09580 205 QRILDYIKpDYVHVLYQGRIVKSG 228
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
28-253 5.83e-06

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 47.64  E-value: 5.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  28 RVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHlieqAGGEVSCDEML---LRRRnrqvieLGEQSASQMRHVRGA 104
Cdd:cd03270    7 REHNLKNVDVDIPRNKLVVITGVSGSGKSSLAFDTIY----AEGQRRYVESLsayARQF------LGQMDKPDVDSIEGL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 105 DIAMIFQEPMTSLNPVFTVGE--QIAESIRLHQGashEEAMVEAKRMLDQVRIPEAKaiLSRYPHQLSGGMRQRVMIAMA 182
Cdd:cd03270   77 SPAIAIDQKTTSRNPRSTVGTvtEIYDYLRLLFA---RVGIRERLGFLVDVGLGYLT--LSRSAPTLSGGEAQRIRLATQ 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 949724212 183 LSCR-PAVL-IADEPTTALDvtiQAQILQLIKVLQ--QDMSMGVIFITHDMGVVAdIADRVLVMYQGEAVETGSV 253
Cdd:cd03270  152 IGSGlTGVLyVLDEPSIGLH---PRDNDRLIETLKrlRDLGNTVLVVEHDEDTIR-AADHVIDIGPGAGVHGGEI 222
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
169-256 8.10e-06

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 49.24  E-value: 8.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  169 LSGGMRQRVMIAMALSCR---PAVLIADEPTTALDVtiqAQILQLIKVLQQDMSMG--VIFITHDMGVVAdIADRVLVM- 242
Cdd:TIGR00630 830 LSGGEAQRIKLAKELSKRstgRTLYILDEPTTGLHF---DDIKKLLEVLQRLVDKGntVVVIEHNLDVIK-TADYIIDLg 905
                          90
                  ....*....|....*....
gi 949724212  243 -----YQGEAVETGSVEQI 256
Cdd:TIGR00630 906 peggdGGGTVVASGTPEEV 924
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
73-240 9.47e-06

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 49.06  E-value: 9.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   73 VSCDEMLLRRRNRQVIELgeqsasqmrHVRGADIAMIFQepMTSLNpvftvgeqiAESIRLHQGASHEEamVEAKRMLDQ 152
Cdd:PRK00635  741 IPCPSCLGKRFLPQVLEV---------RYKGKNIADILE--MTAYE---------AEKFFLDEPSIHEK--IHALCSLGL 798
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  153 VRIPeakaiLSRYPHQLSGGMRQRVMIAMAL---SCRPAVLIADEPTTALDVtiqAQILQLIKVLQQDMSMG--VIFITH 227
Cdd:PRK00635  799 DYLP-----LGRPLSSLSGGEIQRLKLAYELlapSKKPTLYVLDEPTTGLHT---HDIKALIYVLQSLTHQGhtVVIIEH 870
                         170
                  ....*....|...
gi 949724212  228 DMGVVaDIADRVL 240
Cdd:PRK00635  871 NMHVV-KVADYVL 882
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
169-261 1.34e-05

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 46.03  E-value: 1.34e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSMGVIFITHDMGVVADIADRVLVMYqGEAv 248
Cdd:cd03222   72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFE-GEP- 149
                         90
                 ....*....|...
gi 949724212 249 etgSVEQIFHAPQ 261
Cdd:cd03222  150 ---GVYGIASQPK 159
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
350-536 1.40e-05

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 47.02  E-value: 1.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 350 GETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIdtlaASKLQPLRRDIQFIFQDPYASLDPRQ-TVGY---SIL 425
Cdd:cd03237   25 SEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTV----SYKPQYIKADYEGTVRDLLSSITKDFyTHPYfktEIA 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 426 EPLRVHGLLQgdagskrvawllervgllpehawRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIR---GQI 502
Cdd:cd03237  101 KPLQIEQILD-----------------------REVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRlmaSKV 157
                        170       180       190
                 ....*....|....*....|....*....|....
gi 949724212 503 INLMLDLQRElgiAYLFISHDMAVVERISHRVAV 536
Cdd:cd03237  158 IRRFAENNEK---TAFVVEHDIIMIDYLADRLIV 188
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
14-257 2.06e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 48.02  E-value: 2.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    14 AVSNLNIAFEQEQQRVSAVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGEVscdemllrrrnrqvielgeq 93
Cdd:TIGR00957  636 SITVHNATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHV-------------------- 695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    94 sasqmrHVRGAdIAMIFQEPMT---SLNPVFTVGEQIAEsiRLHQGASHEEAMVEAKRML---DQVRIPEaKAIlsryph 167
Cdd:TIGR00957  696 ------HMKGS-VAYVPQQAWIqndSLRENILFGKALNE--KYYQQVLEACALLPDLEILpsgDRTEIGE-KGV------ 759
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQliKVLQqdmSMGV------IFITHDMGVVADIaDRVLV 241
Cdd:TIGR00957  760 NLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFE--HVIG---PEGVlknktrILVTHGISYLPQV-DVIIV 833
                          250
                   ....*....|....*.
gi 949724212   242 MYQGEAVETGSVEQIF 257
Cdd:TIGR00957  834 MSGGKISEMGSYQELL 849
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
446-538 3.83e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 46.73  E-value: 3.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 446 LLERVGLlpEHAW-RYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVsirGQIINlMLDLQREL--GIAYLFISH 522
Cdd:PRK13409 196 VVERLGL--ENILdRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDI---RQRLN-VARLIRELaeGKYVLVVEH 269
                         90
                 ....*....|....*.
gi 949724212 523 DMAVVERISHRVAVMY 538
Cdd:PRK13409 270 DLAVLDYLADNVHIAY 285
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
169-240 5.28e-05

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 45.30  E-value: 5.28e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 169 LSGGMRQRVMIAMALSCR---PAVLIADEPTTALDVtiqAQILQLIKVLQQDMSMG--VIFITHDMGVVAdIADRVL 240
Cdd:cd03271  170 LSGGEAQRIKLAKELSKRstgKTLYILDEPTTGLHF---HDVKKLLEVLQRLVDKGntVVVIEHNLDVIK-CADWII 242
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
28-252 6.41e-05

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 44.87  E-value: 6.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  28 RVSAVRNLSFRLKRGETLAIVGESGSGKSVtalslmhLIEQAGGEVSCDEMLLRRRNRQVIELgeQSASQMRHvrgaDIA 107
Cdd:PRK11614  17 KIQALHEVSLHINQGEIVTLIGANGAGKTT-------LLGTLCGDPRATSGRIVFDGKDITDW--QTAKIMRE----AVA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 108 MIfqepmtslnpvftvgeqiAESIRLHQGASHEEAMVE----AKRMLDQVRIPEAKAILSRYPHQ-------LSGGMRQR 176
Cdd:PRK11614  84 IV------------------PEGRRVFSRMTVEENLAMggffAERDQFQERIKWVYELFPRLHERriqragtMSGGEQQM 145
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 949724212 177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQDmSMGVIFITHDMGVVADIADRVLVMYQGEAV--ETGS 252
Cdd:PRK11614 146 LAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVleDTGD 222
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
349-536 8.00e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 43.13  E-value: 8.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   349 PGETLSLVGESGCGKSTTGRALLRLVESQRGEIIfngqridtlaasklqplrrdiqfifqdpYASLDPRQTVGYSILEPL 428
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVI----------------------------YIDGEDILEEVLDQLLLI 52
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   429 RVHgllqgdagskrvawllervgllpehawRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQII----- 503
Cdd:smart00382  53 IVG---------------------------GKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleel 105
                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 949724212   504 NLMLDLQRELGIAYLFISH------DMAVVERISHRVAV 536
Cdd:smart00382 106 RLLLLLKSEKNLTVILTTNdekdlgPALLRRRFDRRIVL 144
PLN03073 PLN03073
ABC transporter F family; Provisional
33-268 8.11e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 45.62  E-value: 8.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  33 RNLSFRLKRGETLAIVGESGSGKSvtalSLMHLIeqaGGEVSCDEMLLRRRNRQVIELGEQsasqmRHVRGADIAmifQE 112
Cdd:PLN03073 526 KNLNFGIDLDSRIAMVGPNGIGKS----TILKLI---SGELQPSSGTVFRSAKVRMAVFSQ-----HHVDGLDLS---SN 590
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 113 PMTSLNPVFT-VGEQiaeSIRLHQGASHEEAMVEAKRMldqvripeakailsrypHQLSGGMRQRVMIAMALSCRPAVLI 191
Cdd:PLN03073 591 PLLYMMRCFPgVPEQ---KLRAHLGSFGVTGNLALQPM-----------------YTLSGGQKSRVAFAKITFKKPHILL 650
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 949724212 192 ADEPTTALDVTIQAQILQLIKVLQQdmsmGVIFITHDMGVVADIADRVLVMYQGEAVEtgsveqiFHAPQHPYTKAL 268
Cdd:PLN03073 651 LDEPSNHLDLDAVEALIQGLVLFQG----GVLMVSHDEHLISGSVDELWVVSEGKVTP-------FHGTFHDYKKTL 716
AAA_22 pfam13401
AAA domain;
353-435 9.31e-05

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 42.71  E-value: 9.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  353 LSLVGESGCGKSTTGRALLRLVESQRGEIIFngqrIDTLAASKLQPLRRDIQFIFQDPYASLDPRQTVGYSILEPLRVHG 432
Cdd:pfam13401   8 LVLTGESGTGKTTLLRRLLEQLPEVRDSVVF----VDLPSGTSPKDLLRALLRALGLPLSGRLSKEELLAALQQLLLALA 83

                  ...
gi 949724212  433 LLQ 435
Cdd:pfam13401  84 VAV 86
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
314-389 1.10e-04

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 45.17  E-value: 1.10e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 314 LRVRNLVTRFPLRSGilnrvtREVHAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRID 389
Cdd:COG4615  328 LELRGVTYRYPGEDG------DEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVT 397
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
157-228 1.12e-04

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 43.75  E-value: 1.12e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 949724212 157 EAKAILSRYPHQLSGGMRQ------RVMIAMALSCRPAVLIADEPTTALDV-TIQAQILQLIKVLQQDMSMGVIFITHD 228
Cdd:cd03240  104 ESNWPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEeNIEESLAEIIEERKSQKNFQLIVITHD 182
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
31-256 1.53e-04

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 45.12  E-value: 1.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  31 AVRNLSFRLKRGETLAIVGESGSGKSVTALSLMHLIEQAGGE-------VSCDEMLLRRRN---------------RQVI 88
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEawlfgqpVDAGDIATRRRVgymsqafslygeltvRQNL 360
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  89 ELgeqsasqmrHVRgadiamIFQEPmtslnpvftvGEQIAESIrlhqgasheEAMVEaKRMLDQVripeakaiLSRYPHQ 168
Cdd:NF033858 361 EL---------HAR------LFHLP----------AAEIAARV---------AEMLE-RFDLADV--------ADALPDS 397
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQ-LIKVLQQDmsmGV-IFI-THDMGvVADIADRVLVMYQG 245
Cdd:NF033858 398 LPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRlLIELSRED---GVtIFIsTHFMN-EAERCDRISLMHAG 473
                        250
                 ....*....|.
gi 949724212 246 EAVETGSVEQI 256
Cdd:NF033858 474 RVLASDTPAAL 484
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
338-554 1.61e-04

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 44.50  E-value: 1.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 338 HAVENVSFDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIIFNGQRIDTLAASKLQplrrdiqfifqdpyasldpR 417
Cdd:PRK13545  38 YALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAALIAISSGLN-------------------G 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 418 QTVGysiLEPLRVHGLLQGdAGSKRVAWLLERVGLLPEHAwRYPHE----FSGGQRQRICIARALALNPKVIIADESVSA 493
Cdd:PRK13545  99 QLTG---IENIELKGLMMG-LTKEKIKEIIPEIIEFADIG-KFIYQpvktYSSGMKSRLGFAISVHINPDILVIDEALSV 173
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 949724212 494 LDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGTRRAVFEN 554
Cdd:PRK13545 174 GDQTFTKKCLDKMNEF-KEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDH 233
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
446-538 2.34e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 44.00  E-value: 2.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 446 LLERVGLlpEHAW-RYPHEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRElGIAYLFISHDM 524
Cdd:COG1245  196 LAEKLGL--ENILdRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHDL 272
                         90
                 ....*....|....
gi 949724212 525 AVVERISHRVAVMY 538
Cdd:COG1245  273 AILDYLADYVHILY 286
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
40-214 3.33e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 43.94  E-value: 3.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212    40 KRGETLAIVGESGSGKSvtalSLMHLIEQ--AGGEVSCDEMLLRRRNRQvielgeqSASQMR--HVRGADIAMifqepmt 115
Cdd:TIGR00956  787 KPGTLTALMGASGAGKT----TLLNVLAErvTTGVITGGDRLVNGRPLD-------SSFQRSigYVQQQDLHL------- 848
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212   116 slnPVFTVGEQIAESIRLHQGA--SHEEAMveakRMLDQV-RIPE----AKAILSRYPHQLSGGMRQRVMIAMALSCRPA 188
Cdd:TIGR00956  849 ---PTSTVRESLRFSAYLRQPKsvSKSEKM----EYVEEViKLLEmesyADAVVGVPGEGLNVEQRKRLTIGVELVAKPK 921
                          170       180
                   ....*....|....*....|....*..
gi 949724212   189 VLI-ADEPTTALDVTIQAQILQLIKVL 214
Cdd:TIGR00956  922 LLLfLDEPTSGLDSQTAWSICKLMRKL 948
PLN03073 PLN03073
ABC transporter F family; Provisional
433-496 3.51e-04

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 43.70  E-value: 3.51e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 949724212 433 LLQGDAGSKRVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADESVSALDV 496
Cdd:PLN03073 314 LIDAYTAEARAASILAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377
uvrA PRK00349
excinuclease ABC subunit UvrA;
169-234 5.25e-04

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 43.14  E-value: 5.25e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212 169 LSGGMRQRVMIAMALSCRP---AVLIADEPTTALDVtiqAQILQLIKVLQQDMSMG--VIFITHDMGVV--AD 234
Cdd:PRK00349 831 LSGGEAQRVKLAKELSKRStgkTLYILDEPTTGLHF---EDIRKLLEVLHRLVDKGntVVVIEHNLDVIktAD 900
PLN03130 PLN03130
ABC transporter C family member; Provisional
465-514 5.31e-04

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 43.19  E-value: 5.31e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 949724212  465 SGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMldLQRELG 514
Cdd:PLN03130  742 SGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFDKC--IKDELR 789
PLN03232 PLN03232
ABC transporter C family member; Provisional
465-504 6.11e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 43.04  E-value: 6.11e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 949724212  465 SGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIIN 504
Cdd:PLN03232  742 SGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFD 781
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
345-495 9.08e-04

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 40.99  E-value: 9.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 345 FDLWPGETLSLVGESGCGKSTTGRALLRLVESQRGEIifngqRIDTLAASKLQPLRrdiqFIfqdPYASLDPRQTVGYSI 424
Cdd:PRK13543  32 FHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQI-----QIDGKTATRGDRSR----FM---AYLGHLPGLKADLST 99
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 949724212 425 LEPLRVHGLLQGDAGSKRVAWLLERVGlLPEHAWRYPHEFSGGQRQRICIARaLALNPKVI-IADESVSALD 495
Cdd:PRK13543 100 LENLHFLCGLHGRRAKQMPGSALAIVG-LAGYEDTLVRQLSAGQKKRLALAR-LWLSPAPLwLLDEPYANLD 169
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
336-529 1.30e-03

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 40.00  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 336 EVHAVENVSFDLwPGETLSLV-GESGCGKSTtgrallrlvesqrgeIIFngqriDTLAASKLQPLRRDIQFIFQDPYASL 414
Cdd:cd03238    7 NVHNLQNLDVSI-PLNVLVVVtGVSGSGKST---------------LVN-----EGLYASGKARLISFLPKFSRNKLIFI 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 415 DPRQT---VGYSILEPLRVHGLLqgdagskrvawllervgllpehawryphefSGGQRQRICIARALALNPK--VIIADE 489
Cdd:cd03238   66 DQLQFlidVGLGYLTLGQKLSTL------------------------------SGGELQRVKLASELFSEPPgtLFILDE 115
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 949724212 490 SVSALDVSIRGQIINLMLDLqRELGIAYLFISHDMAVVER 529
Cdd:cd03238  116 PSTGLHQQDINQLLEVIKGL-IDLGNTVILIEHNLDVLSS 154
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
464-546 1.38e-03

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 40.93  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 464 FSGGQRQRICIARALALNPKVIIADESVSALDV---SIRGQIINLMLDLQRelgiAYLFISHDMAVVERIS-HRVAVMYL 539
Cdd:PRK09580 146 FSGGEKKRNDILQMAVLEPELCILDESDSGLDIdalKIVADGVNSLRDGKR----SFIIVTHYQRILDYIKpDYVHVLYQ 221

                 ....*..
gi 949724212 540 GQIVEIG 546
Cdd:PRK09580 222 GRIVKSG 228
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
445-538 1.81e-03

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 39.86  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 445 WLLERVGLLPEHAwryphEFSGGQRQRICIARALALNPKVIIADESVSALDVSIRGQIINLMLDLQRELGIAYLFISHDM 524
Cdd:cd03222   58 WDGITPVYKPQYI-----DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDL 132
                         90
                 ....*....|....
gi 949724212 525 AVVERISHRVAVMY 538
Cdd:cd03222  133 AVLDYLSDRIHVFE 146
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
169-234 2.63e-03

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 40.78  E-value: 2.63e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 949724212 169 LSGGMRQRVMIAMALSCR---PAVLIADEPTTAL---DvtiqaqILQLIKVLQQDMSMG--VIFITHDMGVV--AD 234
Cdd:COG0178  827 LSGGEAQRVKLASELSKRstgKTLYILDEPTTGLhfhD------IRKLLEVLHRLVDKGntVVVIEHNLDVIktAD 896
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
166-233 2.84e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 40.07  E-value: 2.84e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 949724212  166 PHQLSGGMRQrvMIAMALSC-----RPAVLIADEPTTALDVTIQAQILQLIKVLQQDMSmGVIFITHDMGVVA 233
Cdd:pfam13304 234 AFELSDGTKR--LLALLAALlsalpKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGA-QLILTTHSPLLLD 303
PLN03140 PLN03140
ABC transporter G family member; Provisional
118-212 3.60e-03

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 40.60  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  118 NPVFTVGEQIAES--IRLHQGASHEEAMVEAKRMLDQVRIPEAKAILSRYP--HQLSGGMRQRVMIAMALSCRPAVLIAD 193
Cdd:PLN03140  965 SPQVTVRESLIYSafLRLPKEVSKEEKMMFVDEVMELVELDNLKDAIVGLPgvTGLSTEQRKRLTIAVELVANPSIIFMD 1044
                          90
                  ....*....|....*....
gi 949724212  194 EPTTALDVTIQAQILQLIK 212
Cdd:PLN03140 1045 EPTSGLDARAAAIVMRTVR 1063
PLN03130 PLN03130
ABC transporter C family member; Provisional
169-258 4.81e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 40.11  E-value: 4.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQliKVLQQDMSMGV-IFITHDMGVVADIaDRVLVMYQGEA 247
Cdd:PLN03130  741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFD--KCIKDELRGKTrVLVTNQLHFLSQV-DRIILVHEGMI 817
                          90
                  ....*....|.
gi 949724212  248 VETGSVEQIFH 258
Cdd:PLN03130  818 KEEGTYEELSN 828
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
85-228 4.86e-03

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 39.72  E-value: 4.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212  85 RQVIELGeqsasqMRHVRGA-----DIAMIFQEPMTSLNpvftvgEQIAESIRL-----HQGASHEEAMVEakRMLDQVR 154
Cdd:PRK11819  88 RENVEEG------VAEVKAAldrfnEIYAAYAEPDADFD------ALAAEQGELqeiidAADAWDLDSQLE--IAMDALR 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 949724212 155 IPEAKAILSryphQLSGGMRQRVmiamALsCR-----PAVLIADEPTTALDvtiqAQ-ILQLIKVLqQDMSMGVIFITHD 228
Cdd:PRK11819 154 CPPWDAKVT----KLSGGERRRV----AL-CRlllekPDMLLLDEPTNHLD----AEsVAWLEQFL-HDYPGTVVAVTHD 219
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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