|
Name |
Accession |
Description |
Interval |
E-value |
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
181-526 |
2.07e-56 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 194.41 E-value: 2.07e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 181 SETLAVHRShELASMQRINEYIVERLHSGVIYVDANQTIKLINGAARQFfncLQTRDLATIDQLSPSLAKKYQDY--LKK 258
Cdd:COG5000 75 TDQLKEQRE-ELEERRRYLETILENLPAGVIVLDADGRITLANPAAERL---LGIPLEELIGKPLEELLPELDLAelLRE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 259 IMDNFRPAKTIINDP---YLRVHFFPTQVGTKVavlILLDDMSAVsQQAQqlKLASLGRFSASIAHELRNPLGAISHAVQ 335
Cdd:COG5000 151 ALERGWQEEIELTRDgrrTLLVRASPLRDDGYV---IVFDDITEL-LRAE--RLAAWGELARRIAHEIKNPLTPIQLSAE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 336 LMGE--NDTLTEDDLRLKEL---IINNCHRMNRVIKNVMQLSRREQSQQQVIDLASFLNQFK---QDFCSHSACSIQIEL 407
Cdd:COG5000 225 RLRRklADKLEEDREDLERAldtIIRQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLalyEPALKEKDIRLELDL 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 408 PEvPLLPFHFDKSQLEQILVILCDNAIQHGKDktgQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTG 487
Cdd:COG5000 305 DP-DLPEVLADRDQLEQVLINLLKNAIEAIEE---GGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPKG 380
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 966513817 488 YGMGLYIARDLCEINQASLNVMNRE-KGCCFTITLNQASE 526
Cdd:COG5000 381 TGLGLAIVKKIVEEHGGTIELESRPgGGTTFTIRLPLAEE 420
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
191-521 |
3.61e-55 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 189.29 E-value: 3.61e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 191 ELASMQRINEYIVERLHSGVIYVDANQTIKLINGAARQFFNC----LQTRDLATIDQLSPSLAKKYQDYLKKiMDNFRPA 266
Cdd:COG3852 1 ALRESEELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLsaeeLLGRPLAELFPEDSPLRELLERALAE-GQPVTER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 267 KTIINDP-----YLRVHFFP-TQVGTKVAVLILLDDMSAVSQQAQQL----KLASLGRFSASIAHELRNPLGAISHAVQL 336
Cdd:COG3852 80 EVTLRRKdgeerPVDVSVSPlRDAEGEGGVLLVLRDITERKRLERELrraeKLAAVGELAAGLAHEIRNPLTGIRGAAQL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 337 MGENdtLTEDDLR-LKELIINNCHRMNRVIKNVMQLSRREQSQQQVIDLASFLNQFKQDFCSHSACSIQIEL---PEVPl 412
Cdd:COG3852 160 LERE--LPDDELReYTQLIIEEADRLNNLVDRLLSFSRPRPPEREPVNLHEVLERVLELLRAEAPKNIRIVRdydPSLP- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 413 lPFHFDKSQLEQILVILCDNAIQHGKDKtGqvEITIKARQTEQNT----------QLMVCDTGPGVKESVMDAIFDPFFS 482
Cdd:COG3852 237 -EVLGDPDQLIQVLLNLVRNAAEAMPEG-G--TITIRTRVERQVTlgglrprlyvRIEVIDNGPGIPEEILDRIFEPFFT 312
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 966513817 483 TVRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:COG3852 313 TKEKGTGLGLAIVQKIVEQHGGTIEVESEPgKGTTFRIYL 352
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
302-521 |
2.08e-47 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 164.69 E-value: 2.08e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 302 QQAQQLKlaslGRFSASIAHELRNPLGAISHAVQLMGENDTLTEDDLR-LKELIINNCHRMNRVIKNVMQLSRREQSQQQ 380
Cdd:COG2205 10 EELERLK----SEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERReLLEIIRESAERLLRLIEDLLDLSRLESGKLS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 381 V----IDLASFLNQFKQDF---CSHSACSIQIELPEvPLLPFHFDKSQLEQILVILCDNAIQHGKDKTgqvEITIKARQT 453
Cdd:COG2205 86 LelepVDLAELLEEAVEELrplAEEKGIRLELDLPP-ELPLVYADPELLEQVLANLLDNAIKYSPPGG---TITISARRE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966513817 454 EQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRT----GYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:COG2205 162 GDGVRISVSDNGPGIPEEELERIFERFYRGDNSrgegGTGLGLAIVKRIVEAHGGTIWVESEPgGGTTFTVTL 234
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
301-521 |
1.78e-46 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 166.13 E-value: 1.78e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 301 SQQAQQLKLASLGRFSASIAHELRNPLGAISHAVQLMGE--NDTLTEDDLRLK-ELIINNCHRMNRVIKNVMQLSRREQS 377
Cdd:COG4191 131 EQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRRrlEDEPDPEELREAlERILEGAERAAEIVRSLRAFSRRDEE 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 378 QQQVIDLASFL--------NQFKqdfcsHSACSIQIELPEvPLLPFHFDKSQLEQILVILCDNAIQ---HGKDKTgqveI 446
Cdd:COG4191 211 EREPVDLNELIdealellrPRLK-----ARGIEVELDLPP-DLPPVLGDPGQLEQVLLNLLINAIDameEGEGGR----I 280
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966513817 447 TIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST--VRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:COG4191 281 TISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFTTkpVGKGTGLGLSISYGIVEKHGGRIEVESEPgGGTTFTITL 358
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
288-521 |
1.82e-44 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 159.69 E-value: 1.82e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 288 VAVLILLDDMSAVSQQAQQLKlaslGRFSASIAHELRNPLGAISHAVQLMgeNDTLTEDDLRLKELIINNCHRMNRVIKN 367
Cdd:COG0642 90 LLLLLLLLALLLLLEEANEAK----SRFLANVSHELRTPLTAIRGYLELL--LEELDEEQREYLETILRSADRLLRLIND 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 368 VMQLSRREQS----QQQVIDLASFLNQFKQDF---CSHSACSIQIELPEvPLLPFHFDKSQLEQILVILCDNAIQHGKDK 440
Cdd:COG0642 164 LLDLSRLEAGklelEPEPVDLAELLEEVVELFrplAEEKGIELELDLPD-DLPTVRGDPDRLRQVLLNLLSNAIKYTPEG 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 441 TgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF----STVRTGYGMGLYIARDLCEINQASLNVMNRE-KGC 515
Cdd:COG0642 243 G---TVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFrtdpSRRGGGTGLGLAIVKRIVELHGGTIEVESEPgKGT 319
|
....*.
gi 966513817 516 CFTITL 521
Cdd:COG0642 320 TFTVTL 325
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
164-521 |
4.88e-38 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 143.92 E-value: 4.88e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 164 IFATAITAWYLANRVRASETLAVHRSHELASMQRINEYIVERLHSGVIYVDANQTIKLINGAARQFFNCLQTRDLATIDQ 243
Cdd:COG5002 23 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 244 LSPSLAKKYQDYLKKIMDNFRPAKTIINDPYLRVHFFPTQVGTKVAVLILLDdmsaVSQQAQQLKLASlgRFSASIAHEL 323
Cdd:COG5002 103 ILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERD----ITELERLEQMRR--EFVANVSHEL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 324 RNPLGAISHAVQLMGENDTLTEDDL-RLKELIINNCHRMNRVIKNVMQLSR----REQSQQQVIDLASFLNQFKQDFCSH 398
Cdd:COG5002 177 RTPLTSIRGYLELLLDGAADDPEERrEYLEIILEEAERLSRLVNDLLDLSRlesgELKLEKEPVDLAELLEEVVEELRPL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 399 SA---CSIQIELPEvPLLPFHFDKSQLEQILVILCDNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDA 475
Cdd:COG5002 257 AEekgIELELDLPE-DPLLVLGDPDRLEQVLTNLLDNAIKYTPEGG---TITVSLREEDDQVRISVRDTGIGIPEEDLPR 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 966513817 476 IFDPFF----STVRT--GYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:COG5002 333 IFERFYrvdkSRSREtgGTGLGLAIVKHIVEAHGGRIWVESEPgKGTTFTITL 385
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
192-521 |
3.36e-32 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 130.47 E-value: 3.36e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 192 LASMQRINEYIVERLHSGVIYVDANQTIKLINGAARQFFNcLQTRDLatidqlspsLAKKY-------QDYLKKIMDNFR 264
Cdd:PRK11360 257 LRETRSLNELILESIADGVIAIDRQGKITTMNPAAEVITG-LQRHEL---------VGKPYselfppnTPFASPLLDTLE 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 265 PAKTIInDPYLRVHFFPTQV-------------GTKVAVLILLDDMSAVS----QQAQQLKLASLGRFSASIAHELRNPL 327
Cdd:PRK11360 327 HGTEHV-DLEISFPGRDRTIelsvstsllhnthGEMIGALVIFSDLTERKrlqrRVARQERLAALGELVAGVAHEIRNPL 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 328 GAISHAVQLMGENDTLTEDDLRLKeLIINNCHRMNRVIKNVMQLSRREQSQQQVIDLASFLN---QFKQDFCSHSACSIQ 404
Cdd:PRK11360 406 TAIRGYVQIWRQQTSDPPSQEYLS-VVLREVDRLNKVIDQLLEFSRPRESQWQPVSLNALVEevlQLFQTAGVQARVDFE 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 405 IEL-PEVPLLPfhFDKSQLEQILVILCDNAIQhGKDKTGQVEITIKaRQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST 483
Cdd:PRK11360 485 TELdNELPPIW--ADPELLKQVLLNILINAVQ-AISARGKIRIRTW-QYSDGQVAVSIEDNGCGIDPELLKKIFDPFFTT 560
|
330 340 350
....*....|....*....|....*....|....*....
gi 966513817 484 VRTGYGMGLYIARDLCEINQASLNVMNR-EKGCCFTITL 521
Cdd:PRK11360 561 KAKGTGLGLALSQRIINAHGGDIEVESEpGVGTTFTLYL 599
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
208-521 |
7.92e-32 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 125.67 E-value: 7.92e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 208 SGVIYVDANQTIKLINGAARQFFNCLQTRDLATIDQLSPSLAKKYQDYLKKIMDNFRPAKTIINDPYLRVHFFPTQVGTK 287
Cdd:COG5807 38 EFVFFIDSKGEILECNDFAEDLYGLSQNEYIGKTFVEEKCILKDEQLYNKEAFDRIEISYLTKNGEFDEIIYPIYYKDGV 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 288 VAVLILLD-DMSAVSQQAQQL----KLASLGRFSASIAHELRNPLGAISHAVQLMgENDTLTEDDLRLKELIINNCHRMN 362
Cdd:COG5807 118 ILGLITVYrDITKRKEAEDKLlrseKLSVAGELAAGIAHEIRNPLTSIKGFLQLL-QESREDSEREEYFNIIISEIDRIN 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 363 RVIKNVMQLSRREQSQQQVIDLASFLNQFKqDFCSHSACS--IQIELPEVPLLPFHF-DKSQLEQILVILCDNAIQHGKD 439
Cdd:COG5807 197 TIITELLVLSKPKKFNFKKLNLNDVLEDVI-ALLSTEAILknISIKYDLADDEPVINgDKNQLKQVFINLIKNAIEAMET 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 440 KTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIARDLCEINQASLNVM-NREKGCCFT 518
Cdd:COG5807 276 GG---NITIKTYVEGDFVVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLSICKKIIEEHNGTIEVEsKPGKGTTFT 352
|
...
gi 966513817 519 ITL 521
Cdd:COG5807 353 IYL 355
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
286-526 |
6.63e-28 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 116.81 E-value: 6.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 286 TKVAVLILLDDMSAVSQQAQQLKLA--SLGRFSASIAHELRNPLGAISHAVQLMGE--NDTLTEDDLRLKELIINNCHRM 361
Cdd:COG4251 254 LLELRLELEELEEELEERTAELERSneELEQFAYVASHDLREPLRKISGFSQLLEEdyGDKLDEEGREYLERIRDAAERM 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 362 NRVIKNVMQLSR--REQSQQQVIDLASFLNQFKQDF-CSHSACSIQIELPEVPLLpfHFDKSQLEQILVILCDNAIQHGK 438
Cdd:COG4251 334 QALIDDLLAYSRvgRQELEFEPVDLNELLEEVLEDLePRIEERGAEIEVGPLPTV--RGDPTLLRQVFQNLISNAIKYSR 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 439 DKTgQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF----STVRTGYGMGLYIARDLCEINQASLNVMNRE-K 513
Cdd:COG4251 412 PGE-PPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQrlhsRDEYEGTGIGLAIVKKIVERHGGRIWVESEPgE 490
|
250
....*....|...
gi 966513817 514 GCCFTITLNQASE 526
Cdd:COG4251 491 GATFYFTLPKAPA 503
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
293-526 |
5.03e-27 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 113.73 E-value: 5.03e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 293 LLDDMsavsqqAQQLKLASLGRFSASIAHELRNPLGAISHAVQLMGENDTLTEDDLRLKELIINNCHRMNRVIKNVMQLS 372
Cdd:PRK10364 224 LQDEM------KRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELV 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 373 RREQSQQQVIDLASFLNQFKQdFCSHSACSIQIEL-----PEVPLLPFhfDKSQLEQILVILCDNAIQH-GKDKTgqveI 446
Cdd:PRK10364 298 KPTHLALQAVDLNDLINHSLQ-LVSQDANSREIQLrftanDTLPEIQA--DPDRLTQVLLNLYLNAIQAiGQHGV----I 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 447 TIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITLNQAS 525
Cdd:PRK10364 371 SVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEgKGATFTLWLPVNI 450
|
.
gi 966513817 526 E 526
Cdd:PRK10364 451 T 451
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
125-526 |
4.46e-26 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 109.94 E-value: 4.46e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 125 IFFASIASCMLLGFSILQYIHSDSDNLSTFFYSGVHGAGIFATAITAWYLANRVRASETLAVHRSHELASMQRINEYIVE 204
Cdd:COG3290 12 LILLILILILLLLLLIILLLILLLVLLLLLFLLFVIILLLLLLILLLILLLLLLLLLAALLLKLLEEIARLVEEREAVLE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 205 RLHSGVIYVDANQTIKLINGAARQFFNclqtrdlatIDQLSPSLAKKYQDYLKkimDNFRPAKTIINDPYLRVHFFPTQV 284
Cdd:COG3290 92 SIREGVIAVDRDGRITLINDAARRLLG---------LDAIGRPIDEVLAEVLE---TGERDEEILLNGRVLVVNRVPIRD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 285 GTKVA-VLILLDDMSAVSQQAQQLKLA-SLGRFSASIAHELRNPLGAISHAVQlMGENDtlteddlRLKELIinnchrmN 362
Cdd:COG3290 160 DGRVVgAVATFRDRTELERLEEELEGVkELAEALRAQRHDFRNHLHTISGLLQ-LGEYD-------EALEYI-------D 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 363 RVIKNVMQLSRREQSQQQVIDLASFLNQfKQDFCSHSACSIQIElPEVPLLPFHFDKSQLEQILVILCDNAIQH-GKDKT 441
Cdd:COG3290 225 EISEELQELIDSLLSRIGNPVLAALLLG-KAARARERGIDLTID-IDSDLPDLPLSDTDLVTILGNLLDNAIEAvEKLPE 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 442 GQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST-VRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTI 519
Cdd:COG3290 303 EERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTkLGEGRGLGLALVKQIVEKYGGTIEVESEEgEGTVFTV 382
|
....*..
gi 966513817 520 TLNQASE 526
Cdd:COG3290 383 RLPKEGE 389
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
191-521 |
4.66e-26 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 111.22 E-value: 4.66e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 191 ELASMQRINEYIVERLHSGVIYVDANQTIKLINGAARQFFNCLQTRDLATIDQ--LSPSLAKKYQDYLKKIMDNFRPAKT 268
Cdd:COG5809 135 ALRESEEKFRLIFNHSPDGIIVTDLDGRIIYANPAACKLLGISIEELIGKSILelIHSDDQENVAAFISQLLKDGGIAQG 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 269 IINDP-------YLRVHFFP-TQVGTKVAVLILLDDMSAVSQQAQQL----KLASLGRFSASIAHELRNPLGAISHAVQL 336
Cdd:COG5809 215 EVRFWtkdgrwrLLEASGAPiKKNGEVDGIVIIFRDITERKKLEELLrkseKLSVVGELAAGIAHEIRNPLTSLKGFIQL 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 337 MgeNDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSRREQSQQQVIDLASFLNQFKQDFCSHSAC-SIQIEL-PEVPLLP 414
Cdd:COG5809 295 L--KDTIDEEQKTYLDIMLSELDRIESIISEFLVLAKPQAIKYEPKDLNTLIEEVIPLLQPQALLkNVQIELeLEDDIPD 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 415 FHFDKSQLEQILVILCDNAIqhgKDKTGQVEITIKARQTEQN-TQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLY 493
Cdd:COG5809 373 ILGDENQLKQVFINLLKNAI---EAMPEGGNITIETKAEDDDkVVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLM 449
|
330 340
....*....|....*....|....*....
gi 966513817 494 IARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:COG5809 450 VSYKIIEEHGGKITVESEVgKGTTFSITL 478
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
200-521 |
1.31e-25 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 109.82 E-value: 1.31e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 200 EYIVERLHSGVIYVDANQTIKLINGAARQFFNcLQTRDLA---TIDQLSPSLAKKYQDYLKKIMDNFRP---AKTIINDP 273
Cdd:COG5805 160 QTLIENSPDLICVIDTDGRILFINESIERLFG-APREELIgknLLELLHPCDKEEFKERIESITEVWQEfiiEREIITKD 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 274 ----YLRVHFFP--TQVGTKVAVLILLDDMSAVSQQAQQL----KLASLGRFSASIAHELRNPLGAISHAVQLMGENDTL 343
Cdd:COG5805 239 grirYFEAVIVPliDTDGSVKGILVILRDITEKKEAEELMarseKLSIAGQLAAGIAHEIRNPLTSIKGFLQLLQPGIED 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 344 TED--DLRLKELIinnchRMNRVIKNVMQLS------RREQSQQQVI-DLASFLN-QFKQDfcshsacSIQIELPEVPLL 413
Cdd:COG5805 319 KEEyfDIMLSELD-----RIESIISEFLALAkpqavnKEKENINELIqDVVTLLEtEAILH-------NIQIRLELLDED 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 414 PF-HFDKSQLEQILVILCDNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGL 492
Cdd:COG5805 387 PFiYCDENQIKQVFINLIKNAIEAMPNGG---TITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKEKGTGLGL 463
|
330 340 350
....*....|....*....|....*....|
gi 966513817 493 YIARDLCEINQASLNVM-NREKGCCFTITL 521
Cdd:COG5805 464 MVSYKIIENHNGTIDIDsKVGKGTTFTITL 493
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
300-526 |
1.43e-25 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 109.45 E-value: 1.43e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 300 VSQQAQQLKLASLGRFSASIAHELRNPLGAISHAVQLMGENDTLTEDDLRLkELIINNCHRMNRVIKNVMQLSRREQSQQ 379
Cdd:COG5808 229 VIQEINTQKLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYPELEDQKYF-DIIQEEIQRINQIVSEFLVLGKPTAKKL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 380 QVIDLASFLNQFkQDFCSHSA----CSIQIELPEVPLLPFhFDKSQLEQILVILCDNAIQHGKDKtGQVEITIKARQTEq 455
Cdd:COG5808 308 ELDDLNELIEEI-LSIIDSEAnlknIRVEKQSLDEPLHIK-CDKDRIKQVLLNLIKNAIEAMKEG-GKLTISIENDDEK- 383
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966513817 456 nTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITLNQASE 526
Cdd:COG5808 384 -AVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEgKGTTFTIRLPLKKE 454
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
418-521 |
6.40e-22 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 90.79 E-value: 6.40e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQILVILCDNAIQHGKDktgQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST-----VRTGYGMGL 492
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPE---GGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTdkrsrKIGGTGLGL 78
|
90 100 110
....*....|....*....|....*....|
gi 966513817 493 YIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:smart00387 79 SIVKKLVELHGGEISVESEPgGGTTFTITL 108
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
291-521 |
4.25e-20 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 91.94 E-value: 4.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 291 LILLDDMSAVSQQ-----AQQLKlaSLGRFSASIAHELRNPLGAISHAVQLM--GENDTLTEDDLRLKELIINNCHR--- 360
Cdd:PRK09303 127 LLQLSDELFVLRQenetlLEQLK--FKDRVLAMLAHDLRTPLTAASLALETLelGQIDEDTELKPALIEQLQDQARRqle 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 361 -MNRVIKNVMQLSRREQSQ----QQVIDLASFLNQFKQDFCSH-SACSIQIE------LPEVpllpfHFDKSQLEQILVI 428
Cdd:PRK09303 205 eIERLITDLLEVGRTRWEAlrfnPQKLDLGSLCQEVILELEKRwLAKSLEIQtdipsdLPSV-----YADQERIRQVLLN 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 429 LCDNAIQHGKDKtGQVEITIKARqTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVR----TGYGMGLYIARDLCEINQA 504
Cdd:PRK09303 280 LLDNAIKYTPEG-GTITLSMLHR-TTQKVQVSICDTGPGIPEEEQERIFEDRVRLPRdegtEGYGIGLSVCRRIVRVHYG 357
|
250
....*....|....*...
gi 966513817 505 SLNVMNR-EKGCCFTITL 521
Cdd:PRK09303 358 QIWVDSEpGQGSCFHFTL 375
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
302-497 |
1.99e-18 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 88.97 E-value: 1.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 302 QQAQQLKlaSLGRFSASIAHELRNPLGAI-SHAVqlMGEN----DTLTEDDLRLkelIINNCHRMNRVIKNVMQLSRREQ 376
Cdd:PRK13837 442 EHARRLE--AVGTLASGIAHNFNNILGAIlGYAE--MALNklarHSRAARYIDE---IISAGARARLIIDQILAFGRKGE 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 377 SQQQVIDLASFLNQfkqdfcshSACSIQIELPEVPLLPFHFDKS---------QLEQILVILCDNAIQhGKDKTGQVEIT 447
Cdd:PRK13837 515 RNTKPFDLSELVTE--------IAPLLRVSLPPGVELDFDQDQEpavvegnpaELQQVLMNLCSNAAQ-AMDGAGRVDIS 585
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966513817 448 IKARQ-------------TEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIARD 497
Cdd:PRK13837 586 LSRAKlrapkvlshgvlpPGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHG 648
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
418-521 |
2.23e-18 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 80.49 E-value: 2.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQILVILCDNAIQHgKDKTGQVEITIKArqtEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRT---GYGMGLYI 494
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKH-AAKAGEITVTLSE---GGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRgggGTGLGLSI 77
|
90 100
....*....|....*....|....*...
gi 966513817 495 ARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:pfam02518 78 VRKLVELLGGTITVESEPgGGTTVTLTL 105
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-521 |
3.04e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 80.13 E-value: 3.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQ---HGKDKTGQVEITIkARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIARDL 498
Cdd:cd16920 1 IQQVLINLVRNGIEamsEGGCERRELTIRT-SPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSI 79
|
90 100
....*....|....*....|....
gi 966513817 499 CEINQASLNVM-NREKGCCFTITL 521
Cdd:cd16920 80 IEAHGGRLSVEsPAGGGATFQFTL 103
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
305-522 |
4.27e-17 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 84.35 E-value: 4.27e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 305 QQLKLASLGRFSASIAHELRNPLGAISHAV-----QLMGENDTLTEDDLrlkELIINNCHRMNRVIKNVMQLSRREQSQQ 379
Cdd:COG4192 426 QAAKMAVVGQTMTSLAHELNQPLNAMSMYLfsakkALEQENYAQLPTSL---DKIEGLIERMDKIIKSLRQFSRKSDTPL 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 380 QVIDLASFLNQFKQDFCS-HSACSIQIELPEVPLLPfhFDKSQLEQILVILCDNAIQHgkdKTGQVEITIKARQTEQNTQ 458
Cdd:COG4192 503 QPVDLRQVIEQAWELVESrAKPQQITLHIPDDLMVQ--GDQVLLEQVLVNLLVNALDA---VATQPQISVDLLSNAENLR 577
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966513817 459 LMVCDTGPGVkeSVMDAIFDPFFSTVRTGYGMGLYIARDLCEINQASLNVM-NREKGCCFTITLN 522
Cdd:COG4192 578 VAISDNGNGW--PLVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLAsTLERGAMVILEFN 640
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
318-525 |
1.07e-16 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 82.58 E-value: 1.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 318 SIAHELRNPLGAISHAVQLMGEnDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSRREQSQQ----QVIDLASFLNQFKQ 393
Cdd:PRK11100 262 TLTHELKSPLAAIRGAAELLQE-DPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQRQElevlEPVALAALLEELVE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 394 DFCSH-SACSIQIELpEVPLLPFHFDKSQLEQILVILCDNAI----QHGkdktgqvEITIKARQTEQNTQLMVCDTGPGV 468
Cdd:PRK11100 341 AREAQaAAKGITLRL-RPDDARVLGDPFLLRQALGNLLDNAIdfspEGG-------TITLSAEVDGEQVALSVEDQGPGI 412
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966513817 469 KESVMDAIFDPFFSTVRT-----GYGMGLYIARDLCEINQASLNVMNR-EKGCCFTITLNQAS 525
Cdd:PRK11100 413 PDYALPRIFERFYSLPRPangrkSTGLGLAFVREVARLHGGEVTLRNRpEGGVLATLTLPRHF 475
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
299-521 |
2.70e-16 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 82.39 E-value: 2.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 299 AVSQQAQQLKLAS----LgRFS--ASIAHELRNPLGAishavqLMGENDTLTED-------------DLRLKEL----II 355
Cdd:PRK10490 646 TLTASEEQARLASereqL-RNAllAALSHDLRTPLTV------LFGQAEILTLDlasegspharqasEIRQQVLnttrLV 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 356 NNCHRMNRVIKNVMQLSRREQSQQQVIdlASFLNQFKQDFCSHSacsIQIELPEvPLLPFHFDKSQLEQILVILCDNAIQ 435
Cdd:PRK10490 719 NNLLDMARIQSGGFNLRKEWLTLEEVV--GSALQMLEPGLSGHP---INLSLPE-PLTLIHVDGPLFERVLINLLENAVK 792
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 436 HGKDktgQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF-----STVrTGYGMGLYIARDLCEINQASLNVMN 510
Cdd:PRK10490 793 YAGA---QAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFArgnkeSAI-PGVGLGLAICRAIVEVHGGTIWAEN 868
|
250
....*....|..
gi 966513817 511 REK-GCCFTITL 521
Cdd:PRK10490 869 RPEgGACFRVTL 880
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
308-521 |
1.93e-15 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 78.37 E-value: 1.93e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 308 KLASLGRFSASIAHELRNPLGAISHAVQLMGENDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSRREQSQQQVIDLASF 387
Cdd:COG5806 197 KLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKPQPEKLEKIDVSEE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 388 LNQFK---QDFCSHSACSIQIELPevPLLPFHFDKSQLEQILVILCDNAIQHGKDKtGqvEITIKARQTEQNTQLMVCDT 464
Cdd:COG5806 277 LEHVIdvlSPYANMNNVEIQTELE--PGLYIEGDRQKLQQCLINIIKNGIEAMPNG-G--TLTIDVSIDKNKVIISIKDT 351
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 966513817 465 GPGVKESVMDAIFDPFFSTVRTGYGMGLYIARDLCEINQASLNVMNR-EKGCCFTITL 521
Cdd:COG5806 352 GVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEvGKGTTFTITL 409
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
302-505 |
1.65e-14 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 74.73 E-value: 1.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 302 QQAQQLKLASLGRfsaSIAHELRNPLGAISHAVQLMGE---NDTLTEddlrLKELIINNCHRMNRVIKNVMQLSRREQSQ 378
Cdd:PRK11073 123 QHAQQVAARDLVR---GLAHEIKNPLGGLRGAAQLLSKalpDPALTE----YTKVIIEQADRLRNLVDRLLGPQRPGTHV 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 379 QQVIDlaSFLNQFKQDFCSHSACSIQIELPEVPLLP-FHFDKSQLEQILVILCDNAIQHGKDKTGqvEITIKARQTEQNT 457
Cdd:PRK11073 196 TESIH--KVAERVVQLVSLELPDNVRLIRDYDPSLPeLAHDPDQIEQVLLNIVRNALQALGPEGG--TITLRTRTAFQLT 271
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 966513817 458 ----------QLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIARDLceINQAS 505
Cdd:PRK11073 272 lhgeryrlaaRIDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNL--IDQHS 327
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
309-373 |
1.32e-13 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 65.70 E-value: 1.32e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966513817 309 LASLGRFSASIAHELRNPLGAISHAVQLMGENDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSR 373
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-521 |
1.10e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 64.02 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIqhgkDKTGQVE---ITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST--VRTGYGMGLYIAR 496
Cdd:cd16976 1 IQQVLMNLLQNAL----DAMGKVEnprIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTkpVGKGTGLGLSISY 76
|
90 100
....*....|....*....|....*.
gi 966513817 497 DLCEINQASLNVMNREK-GCCFTITL 521
Cdd:cd16976 77 GIVEEHGGRLSVANEEGaGARFTFDL 102
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
422-521 |
2.99e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 63.28 E-value: 2.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIqhgkdK---TGQVEITIKARQTEQNT-QLMVC--DTGPGVKESVMDAIFDPFF----STVR--TGYG 489
Cdd:cd16922 1 LRQILLNLLGNAI-----KfteEGEVTLRVSLEEEEEDGvQLRFSveDTGIGIPEEQQARLFEPFSqadsSTTRkyGGTG 75
|
90 100 110
....*....|....*....|....*....|...
gi 966513817 490 MGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:cd16922 76 LGLAISKKLVELMGGDISVESEPgQGSTFTFTL 108
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
317-521 |
4.81e-12 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 68.90 E-value: 4.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 317 ASIAHELRNPLGAISHAVQLMgENDTLTEDDLRLKE----------LIINNCHRMNRVIKNVMQLSRREQSQQQVIDLAS 386
Cdd:PRK15347 403 TTISHEIRTPLNGVLGALELL-QNTPLTAEQMDLADtarqctlsllAIINNLLDFSRIESGQMTLSLEETALLPLLDQAM 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 387 FLNQFKqdfcshsACSIQIEL-----PEVPLLpFHFDKSQLEQILVILCDNAIQHGKDktGQVEITIKARQteQNTQLMV 461
Cdd:PRK15347 482 LTIQGP-------AQSKSLTLrtfvgAHVPLY-LHLDSLRLRQILVNLLGNAVKFTET--GGIRLRVKRHE--QQLCFTV 549
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966513817 462 CDTGPGVKESVMDAIFDPFF--STVRTGYGMGLYIARDLCEINQASLNvMNRE--KGCCFTITL 521
Cdd:PRK15347 550 EDTGCGIDIQQQQQIFTPFYqaDTHSQGTGLGLTIASSLAKMMGGELT-LFSTpgVGSCFSLVL 612
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
311-376 |
7.34e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 60.66 E-value: 7.34e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966513817 311 SLGRFSASIAHELRNPLGAISHAVQLMgENDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSRREQ 376
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELL-LDTELSEEQREYLETILREAERLLRLINDLLDLSRIEA 65
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-522 |
1.29e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 61.53 E-value: 1.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVilcdNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFS-----TVRTGYGMGLYIAR 496
Cdd:cd16948 10 IGQIVS----NALKYSKQGG---KIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTgengrNFQESTGMGLYLVK 82
|
90 100
....*....|....*....|....*..
gi 966513817 497 DLCEINQASLNVMNRE-KGCCFTITLN 522
Cdd:cd16948 83 KLCDKLGHKIDVESEVgEGTTFTITFP 109
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
420-521 |
1.90e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 60.90 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 420 SQLEQILVILCDNAIQHgkdKTGQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST--VRTGYGMGLYIARD 497
Cdd:cd16943 2 SQLNQVLLNLLVNAAQA---MEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTkpVGEGTGLGLSLSYR 78
|
90 100
....*....|....*....|....*
gi 966513817 498 LCEINQASLNVMNRE-KGCCFTITL 521
Cdd:cd16943 79 IIQKHGGTIRVASVPgGGTRFTIIL 103
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
311-376 |
2.09e-11 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 59.53 E-value: 2.09e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966513817 311 SLGRFSASIAHELRNPLGAISHAVQLMgENDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSRREQ 376
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELL-RDEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
163-496 |
3.60e-11 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 65.32 E-value: 3.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 163 GIFATAITAWYLANRVR---------ASETLAVHRShelASMQRINEyiverlhsGVIYVDANQTIKLINGAARQFFNCL 233
Cdd:PRK11086 189 GALVGLIGTVILVRVLKrilfglepyEISTLFEQRQ---AMLQSIKE--------GVIAVDDRGEVTLINDEAKRLFNYK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 234 QTRDLATIDQLSPSLAKKyqDYLKKIMDNFRPAK---TIINDPYLRVHFFPTQVGTKVAVLI-LLDDMSAVSQQAQQL-- 307
Cdd:PRK11086 258 KGLEDDPLGTDVESWMPV--SRLKEVLRTGTPRRdeeININGRLLLTNTVPVRVNGEIIGAIaTFRDKTEVRQLAQRLdg 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 308 -KL-ASLGRfsaSIAHELRNPLGAISHAVQlMGENDtlteddlRLKELIINNCHRMNRVIKNVMqlsRREQSQqqVIdlA 385
Cdd:PRK11086 336 mVNyADALR---AQSHEFMNKLHVILGLLH-LKSYD-------QLEDYILKTANNYQEEIGSLL---GKIKSP--VI--A 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 386 SFLnQFKQDFCSHSACSIQIElpEVPLLPFHFDKSQ-LEQILVI--LCDNAIQH-GKDKTGQVEITIKarqtEQNTQLM- 460
Cdd:PRK11086 398 GFL-LGKISRARELGITLIIS--EDSQLPDSGDEDQvHELITILgnLIENALEAvGGEEGGEISVSLH----YRNGWLHc 470
|
330 340 350
....*....|....*....|....*....|....*..
gi 966513817 461 -VCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYIAR 496
Cdd:PRK11086 471 eVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVK 507
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-521 |
6.10e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 60.34 E-value: 6.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 383 DLASFLNQFKQDfcshSACSIQIELPevPLLPFHFDKSQLEQILVILCDNAIQHGkdkTGQVEITikARQTEQNTQLMVC 462
Cdd:cd16954 5 SLCSALNKVYQR----KGVSISLDIS--PELRFPGERNDLMELLGNLLDNACKWC---LEFVEVT--ARQTDGGLHLIVD 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966513817 463 DTGPGVKESVMDAIFD--PFFSTVRTGYGMGLYIARDLCEINQASLNVMN-REKGCCFTITL 521
Cdd:cd16954 74 DDGPGVPESQRSKIFQrgQRLDEQRPGQGLGLAIAKEIVEQYGGELSLSDsPLGGARFEVVF 135
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
317-514 |
2.42e-10 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 62.62 E-value: 2.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 317 ASIAHELRNPLGAISHAVQLMGEndtltEDDLrLKELIINNCHRMNRVIKNVMQLSRREQSQQ-QVIDLASFLNQFKQDF 395
Cdd:PRK09467 234 AGVSHDLRTPLTRIRLATEMMSE-----EDGY-LAESINKDIEECNAIIEQFIDYLRTGQEMPmEMADLNALLGEVIAAE 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 396 cSHSACSIQIELPEVPlLPFHFDKSQLEQILVILCDNAIQHGKDktgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDA 475
Cdd:PRK09467 308 -SGYEREIETALQPGP-IEVPMNPIAIKRALANLVVNAARYGNG-----WIKVSSGTEGKRAWFQVEDDGPGIPPEQLKH 380
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 966513817 476 IFDPFF--STVRT--GYGMGLYIARDLCEINQASLNVMNREKG 514
Cdd:PRK09467 381 LFQPFTrgDSARGssGTGLGLAIVKRIVDQHNGKVELGNSEEG 423
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-521 |
4.91e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 56.81 E-value: 4.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQHGKDKTGQveITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFS------TVRTGYGMGLYIA 495
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTGR--ITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTerpaneAFGQHSGLGLSIS 78
|
90 100 110
....*....|....*....|....*....|.
gi 966513817 496 RDLCEINQASLNVMNRE-----KGCCFTITL 521
Cdd:cd16953 79 RQIIEAHGGISVAENHNqpgqvIGARFTVQL 109
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
314-514 |
8.11e-10 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 60.82 E-value: 8.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 314 RFSASIAHELRNPLGAIShaVQlmGENDTLTEDDLRLKELIINNCH----RMNRVIKNVMQLSRREQSQQ----QVIDLA 385
Cdd:PRK10337 239 RFTSDAAHELRSPLAALK--VQ--TEVAQLSDDDPQARKKALLQLHagidRATRLVDQLLTLSRLDSLDNlqdvAEIPLE 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 386 SFLNQFKQDFCSH---SACSIQIELPEVPLLpfHFDKSQLEQILVI-LCDNAIQHgKDKTGQVEITIKARqteqntQLMV 461
Cdd:PRK10337 315 DLLQSAVMDIYHTaqqAGIDVRLTLNAHPVI--RTGQPLLLSLLVRnLLDNAIRY-SPQGSVVDVTLNAR------NFTV 385
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 966513817 462 CDTGPGVKESVMDAIFDPFF---STVRTGYGMGLYIARDLCEINQASLNVMNREKG 514
Cdd:PRK10337 386 RDNGPGVTPEALARIGERFYrppGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEG 441
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
315-515 |
1.02e-09 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 60.37 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 315 FSASIAHELRNPLGAISHAVQLMGENDTLTEDDLrlkeliINNCHRMNRVIKNVMQLSRREQS----QQQVIDLASFLNQ 390
Cdd:PRK10755 140 FTADVAHELRTPLAGIRLHLELLEKQHHIDVAPL------IARLDQMMHTVEQLLQLARAGQSfssgHYQTVKLLEDVIL 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 391 FKQDFCS--HSACSIQIELPEVPL-LPFHFDKSQLEQILVILCDNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPG 467
Cdd:PRK10755 214 PSQDELSemLEQRQQTLLLPESAAdITVQGDATLLRLLLRNLVENAHRYSPEGS---TITIKLSQEDGGAVLAVEDEGPG 290
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 966513817 468 VKESVMDAIFDPF--FSTVRTGYGMGLYIARDLCEINQASLNVMNREKGC 515
Cdd:PRK10755 291 IDESKCGELSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQERS 340
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
315-521 |
2.53e-09 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 59.25 E-value: 2.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 315 FSASIAHELRNPLGAISHAVQLMGENDtlTEDDLRLKEL--IINNCHRMNRVIKNVMQLSRREQSQQ----QVIDLASFL 388
Cdd:PRK11006 207 FFANVSHELRTPLTVLQGYLEMMQDQP--LEGALREKALhtMREQTQRMEGLVKQLLTLSKIEAAPTidlnEKVDVPMML 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 389 NQFKQDFCSHSACSIQIELPEVPLLPFHFDKSQLEQILVILCDNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGV 468
Cdd:PRK11006 285 RVLEREAQTLSQGKHTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGT---HITVRWQRVPQGAEFSVEDNGPGI 361
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 469 KESVMDAIFDPFF------STVRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:PRK11006 362 APEHIPRLTERFYrvdkarSRQTGGSGLGLAIVKHALSHHDSRLEIESEVgKGTRFSFVL 421
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-521 |
8.12e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 53.10 E-value: 8.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQHGKDKtgqveITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF--STVRT----GYGMGLYIA 495
Cdd:cd16949 1 LARALENVLRNALRYSPSK-----ILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYrvDSARDresgGTGLGLAIA 75
|
90 100
....*....|....*....|....*..
gi 966513817 496 RDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:cd16949 76 ERAIEQHGGKIKASNRKpGGLRVRIWL 102
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
416-514 |
1.46e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 52.79 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 416 HFDKSQLEQILVILCDNAIQHGKdKTGQVEITIKARQTeqnTQLMVCDTGPGVKESVMDAIFDPFF---STVRTGYGMGL 492
Cdd:cd16940 8 QGDALLLFLLLRNLVDNAVRYSP-QGSRVEIKLSADDG---AVIRVEDNGPGIDEEELEALFERFYrsdGQNYGGSGLGL 83
|
90 100
....*....|....*....|..
gi 966513817 493 YIARDLCEINQASLNVMNREKG 514
Cdd:cd16940 84 SIVKRIVELHGGQIFLGNAQGG 105
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-498 |
1.47e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 52.79 E-value: 1.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQHGKDKTGqvEITIKARQTEQNT----------QLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMG 491
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGG--EIILRTRTQRQVTlghprhrlalRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLG 78
|
....*..
gi 966513817 492 LYIARDL 498
Cdd:cd16918 79 LAIAQNI 85
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
425-521 |
2.07e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 56.56 E-value: 2.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 425 ILVILCDNAIQHG-KDKTGQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPfFSTVRTGYGMGLYIARD---LCE 500
Cdd:COG2972 340 ILQPLVENAIEHGiEPKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEE-LSSKGEGRGIGLRNVRErlkLYY 418
|
90 100
....*....|....*....|.
gi 966513817 501 INQASLNVmNREKGCCFTITL 521
Cdd:COG2972 419 GEEYGLEI-ESEPGEGTTVTI 438
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
314-521 |
2.49e-08 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 57.05 E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 314 RFSASIAHELRNPLGAISHAVQLMGENDTLTEDDLRLKELIINNCHRMNRVIKNVMQLSRRE----QSQQQVIDLASFLN 389
Cdd:PRK09959 714 QFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIEsgnyQLQPQWVDIPTLVQ 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 390 QFKQDFCSHSAcSIQIELPEVPLLPFHF----DKSQLEQILVILCDNAIQHGKDktGQVEITIKARQTEQN---TQLMVC 462
Cdd:PRK09959 794 NTCHSFGAIAA-SKSIALSCSSTFPDHYlvkiDPQAFKQVLSNLLSNALKFTTE--GAVKITTSLGHIDDNhavIKMTIM 870
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966513817 463 DTGPGVKESVMDAIFDPFFSTV----RTGYGMGLYIARDLCEINQASLNVMNREK-GCCFTITL 521
Cdd:PRK09959 871 DSGSGLSQEEQQQLFKRYSQTSagrqQTGSGLGLMICKELIKNMQGDLSLESHPGiGTTFTITI 934
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
403-521 |
6.80e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 51.36 E-value: 6.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 403 IQIELPEVPLLPfHFDKSQLEQILVILCDNAIQHGKDktGQVeITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFS 482
Cdd:cd16947 3 VEINIPDRPIYA-NANTEALQRILKNLISNAIKYGSD--GKF-LGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYT 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 966513817 483 ------TVRTGYGMGLYIARDLCEINQASLNVMNR--EKgCCFTITL 521
Cdd:cd16947 79 ledsrnSAKQGNGLGLTITKRLAESMGGSIYVNSKpyEK-TVFTVTL 124
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
254-521 |
7.70e-08 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 55.30 E-value: 7.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 254 DYLKKIMDNFRPAKTIINdpYLRVHFfPTQVGTKVAVLILL----DDMSAVSQQAQQLKLAslgrFSASIAHELRNPLGA 329
Cdd:PRK11466 389 DTIGRLMDAFRSNVHALN--RHREQL-AAQVKARTAELQELviehRQARAEAEKASQAKSA----FLAAMSHEIRTPLYG 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 330 ISHAVQLMGENDTLTE--DDLRLkelIINNCHRMNRVIKNVMQLSRREQSQQQVI---------DLASFLNQFKQDFCSH 398
Cdd:PRK11466 462 ILGTAQLLADNPALNAqrDDLRA---ITDSGESLLTILNDILDYSAIEAGGKNVSvsdepfeprPLLESTLQLMSGRVKG 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 399 SACSIQIELPEVPLLPFHFDKSQLEQILVILCDNAIQHgkdkTGQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFD 478
Cdd:PRK11466 539 RPIRLATDIADDLPTALMGDPRRIRQVITNLLSNALRF----TDEGSIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQ 614
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 966513817 479 PF--FSTVRTGYGMGLYIARDLCEINQASLNVMNR-EKGCCFTITL 521
Cdd:PRK11466 615 PFvqVSGKRGGTGLGLTISSRLAQAMGGELSATSTpEVGSCFCLRL 660
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-514 |
8.14e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 50.14 E-value: 8.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQHGKdktGQVEItikARQTEQN-TQLMVCDTGPGVKESVMDAIFDPFF--STVRT--GYGMGLYIAR 496
Cdd:cd16950 1 LKRVLSNLVDNALRYGG---GWVEV---SSDGEGNrTRIQVLDNGPGIAPEEVDELFQPFYrgDNARGtsGTGLGLAIVQ 74
|
90
....*....|....*...
gi 966513817 497 DLCEINQASLNVMNREKG 514
Cdd:cd16950 75 RISDAHGGSLTLANRAGG 92
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
429-521 |
1.02e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 49.98 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 429 LCDNAIQHGKDKTGQV-EITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST-VRTGYGMGLYIARDLCEINQASL 506
Cdd:cd16915 8 LIDNALDALAATGAPNkQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTkGQGERGIGLALVRQSVERLGGSI 87
|
90
....*....|....*.
gi 966513817 507 NVMNREK-GCCFTITL 521
Cdd:cd16915 88 TVESEPGgGTTFSIRI 103
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
418-521 |
1.19e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 50.23 E-value: 1.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQILVILCDNA---IQHGKDKTGQVEITIKARQtEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRTGYGMGLYI 494
Cdd:cd16944 1 DTTQISQVLTNILKNAaeaIEGRPSDVGEVRIRVEADQ-DGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAI 79
|
90 100
....*....|....*....|....*...
gi 966513817 495 ARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:cd16944 80 VKKIMEEHGGRISLSNREaGGACIRIIL 107
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
277-498 |
5.50e-07 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 52.21 E-value: 5.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 277 VHFFPTQVGtkvAVLILLDDMSAVSQQAQQLKLASLGR--------------FSASIaHELRNPLGAISHAVQLMGENDT 342
Cdd:TIGR02938 231 SFFCAAEQP---YLLLTIADISNLREEQERARLSALQAlmaeeerleairetLSAAI-HRLQGPMNLISAAISVLQRRGD 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 343 LTEDDLRLKELIinncHRMNRVIKNVMQLSRREQSQQQVIDLASFLNQFKQDFCSHS-----ACSIQIELPEVPLLPFHF 417
Cdd:TIGR02938 307 DAGNPASAAMLQ----QALSAGREHMEALRQVIPQSPQEIVVPVNLNQILRDVITLStprllAAGIVVDWQPAATLPAIL 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 -DKSQLEQILVILCDNAIQH-GKDKTGQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFST---VRTGYGMGL 492
Cdd:TIGR02938 383 gRELQLRSLFKALVDNAIEAmNIKGWKRRELSITTALNGDLIVVSILDSGPGIPQDLRYKVFEPFFTTkggSRKHIGMGL 462
|
....*.
gi 966513817 493 YIARDL 498
Cdd:TIGR02938 463 SVAQEI 468
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-521 |
7.02e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 47.84 E-value: 7.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVR-----TGYGMGLYIAR 496
Cdd:cd16945 5 LRQAINNLLDNAIDFSPEGG---LIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRphsgqKSTGLGLAFVQ 81
|
90 100
....*....|....*....|....*
gi 966513817 497 DLCEINQASLNVMNREKGCCFTITL 521
Cdd:cd16945 82 EVAQLHGGRITLRNRPDGVLAFLTL 106
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
418-504 |
7.51e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 47.84 E-value: 7.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQILVILCDNAIQHgKDKTGQVEItiKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF--STVRT----GYGMG 491
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRY-TDTGGKLRI--RAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYrvESSRNrasgGSGLG 77
|
90
....*....|...
gi 966513817 492 LYIArdlCEINQA 504
Cdd:cd16946 78 LAIC---HNIALA 87
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
418-514 |
1.58e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 46.69 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQILVILCDNAIQHGKDKtGQVEITIKARQteQNTQLMVCDTGPGVKESVMDAIFDPFFS--TVRTG---YGMGL 492
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEG-GTVSISIYDEE--EYLYFEIWDNGHGFSEQDLKKALELFYRddTSRRSgghYGMGL 77
|
90 100
....*....|....*....|..
gi 966513817 493 YIARDLCEINQASLNVMNREKG 514
Cdd:cd16975 78 YIAKNLVEKHGGSLIIENSQKG 99
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
297-494 |
1.74e-06 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 50.32 E-value: 1.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 297 MSAVSQ--QAQQlklaslgRFSASIAHELRNPLGAISHAVQLM----GENDTLTEddlrlkelIINNCHRMNRVIKNVMQ 370
Cdd:PRK09470 233 VTALERmmTSQQ-------RLLSDISHELRTPLTRLQLATALLrrrqGESKELER--------IETEAQRLDSMINDLLV 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 371 LSRREQSQQQ-------------VIDLASF-LNQFKQDFcshsacsiqiELPEVP----------LLpfhfdKSQLEQIL 426
Cdd:PRK09470 298 LSRNQQKNHLeretfkanslwseVLEDAKFeAEQMGKSL----------TVSAPPgpwpingnpnAL-----ASALENIV 362
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966513817 427 vilcDNAIQHGKDktgQVEITIKArqteQNTQLMVC--DTGPGVKESVMDAIFDPFF--STVRT----GYGMGLYI 494
Cdd:PRK09470 363 ----RNALRYSHT---KIEVAFSV----DKDGLTITvdDDGPGVPEEEREQIFRPFYrvDEARDresgGTGLGLAI 427
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
303-492 |
7.81e-06 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 48.51 E-value: 7.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 303 QAQqlKLASLGRFSASIAHELRNPLGAIS-HA--VQLMGENDTLTEDDL-RLKELIINNCHRMNRVIKNVMQLSRREQSQ 378
Cdd:PRK13557 156 QAQ--KMEALGQLTGGIAHDFNNLLQVMSgYLdvIQAALSHPDADRGRMaRSVENIRAAAERAATLTQQLLAFARKQRLE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 379 QQVIDLASFLNQFKqDFCSHS---ACSIQIELPEvPLLPFHFDKSQLEQILVILCDN---AIQHGKDKTGQVE-ITIKAR 451
Cdd:PRK13557 234 GRVLNLNGLVSGMG-ELAERTlgdAVTIETDLAP-DLWNCRIDPTQAEVALLNVLINardAMPEGGRVTIRTRnVEIEDE 311
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 966513817 452 QTEQNTQLM--------VCDTGPGVKESVMDAIFDPFFSTVRTGYGMGL 492
Cdd:PRK13557 312 DLAMYHGLPpgryvsiaVTDTGSGMPPEILARVMDPFFTTKEEGKGTGL 360
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
444-500 |
8.17e-06 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 48.48 E-value: 8.17e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 966513817 444 VEITikARQTEQNTQLMVCDTGPGVKESVMDAIFD--PFFSTVRTGYGMGLYIARDLCE 500
Cdd:PRK10815 398 VEIS--ARQTDEHLHIVVEDDGPGIPESKRELIFDrgQRADTLRPGQGLGLSVAREITE 454
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
313-522 |
1.37e-05 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 48.01 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 313 GRFSASIAHELRNPLGAI---SHAvqLMgenDT-LTEDDLR-LKEL---------IINNCHRMNRVIKNVMQLSrreqsq 378
Cdd:PRK11091 284 TTFISTISHELRTPLNGIvglSRI--LL---DTeLTAEQRKyLKTIhvsaitlgnIFNDIIDMDKMERRKLQLD------ 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 379 QQVIDLASFLNqfkqDFCSHSACSIQ---IELPEVPLLPF-HF---DKSQLEQILVILCDNAIQHGKDktGQVEITIKAr 451
Cdd:PRK11091 353 NQPIDFTDFLA----DLENLSGLQAEqkgLRFDLEPLLPLpHKvitDGTRLRQILWNLISNAVKFTQQ--GGVTVRVRY- 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 452 qtEQNTQLM--VCDTGPGVKESVMDAIFDPFF-------STVRTGYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:PRK11091 426 --EEGDMLTfeVEDSGIGIPEDELDKIFAMYYqvkdshgGKPATGTGIGLAVSKRLAQAMGGDITVTSEEgKGSCFTLTI 503
|
.
gi 966513817 522 N 522
Cdd:PRK11091 504 H 504
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
276-496 |
1.40e-05 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 47.68 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 276 RVHFFPTQVGTKVAVlillddmsAVSQQAQQLK--LASLGRFSASIAHELRNPLgaishaVQL-----MGENdtLTEDDl 348
Cdd:PRK10604 182 RIHFDEGSSLERLGV--------AFNQMADNINalIASKKQLIDGIAHELRTPL------VRLryrleMSDN--LSAAE- 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 349 rlKELIINNCHRMNRVIKNVMQLSRREQSQQ----QVIDLASFLNQFKQDFCS-HSACSIQIELPEVPLlPFHFDKSQLE 423
Cdd:PRK10604 245 --SQALNRDIGQLEALIEELLTYARLDRPQNelhlSEPDLPAWLSTHLADIQAvTPEKTVRLDTPHQGD-YGALDMRLME 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 424 QILVILCDNAIQHGkdkTGQVEITIkARQTEQNTqLMVCDTGPGVKESVMDAIFDPFfstVRT---------GYGMGLYI 494
Cdd:PRK10604 322 RVLDNLLNNALRYA---HSRVRVSL-LLDGNQAC-LIVEDDGPGIPPEERERVFEPF---VRLdpsrdratgGCGLGLAI 393
|
..
gi 966513817 495 AR 496
Cdd:PRK10604 394 VH 395
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
412-499 |
3.21e-05 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 43.75 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 412 LLPFHFDKSQLEQILVI---LCDNAIQHGKDKTGQVEITIKARQTEQNTQLMVCDTGPGvkesvmdaiFDPF-----FST 483
Cdd:COG2172 22 LRELGLDEDDADDLVLAvseAVTNAVRHAYGGDPDGPVEVELELDPDGLEIEVRDEGPG---------FDPEdlpdpYST 92
|
90
....*....|....*.
gi 966513817 484 VRTGyGMGLYIARDLC 499
Cdd:COG2172 93 LAEG-GRGLFLIRRLM 107
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
62-521 |
3.51e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 46.44 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 62 LLFLYLQYLHRPGFKTQVIISGTMDIIAQALLISLLGNTRSWLGILLNATIAALSILVPGRLAIFFASIASCMLLGFSIL 141
Cdd:COG3920 1 LLLALLLLLLLALAALLLLAALLLLAAALLLALLALLLLALLLLALLLASALLALLALSAAALAAALAVALAAAVGAAAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 142 QYIHSDSDNLSTFFYSGVHGAGIFATAITAWYLANRVRASETLAVHRSHELASMQRINEYIVERLHSGVIYVDANQTIKL 221
Cdd:COG3920 81 LLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 222 INGAARQFFNCLQTRDLATIDQLSPSLAKKYQDYLKKIMDNFRPAKTIINDPYLRVHFFPTQVGTKVAVLILLDDMSAVS 301
Cdd:COG3920 161 LLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 302 QQAQQLKLASLGRFSASIAHELRNPLGAISHAVQLMGEND----------TLTEDDLRLKELiinnCHRmnrvIKNVMQL 371
Cdd:COG3920 241 LERRRRARGLGRLLLLLLLLLLLLRALLLLAAGIRLVITErkraeeeleaSLEEKELLLREL----HHR----VKNNLQV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 372 --------SRR----------EQSQQQV------------------IDLASFLNQFKQDFC-SHSACSIQIELpEVPllP 414
Cdd:COG3920 313 vssllrlqARRaddpearealEESQNRIqalalvhellyqsedwegVDLRDYLRELLEPLRdSYGGRGIRIEL-DGP--D 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 415 FHFDKSQLEQI-LVI--LCDNAIQHGKDKTGQVEITIKARQTEQNTQLMVCDTGPGVKESVmdaifdpffsTVRTGYGMG 491
Cdd:COG3920 390 VELPADAAVPLgLILneLVTNALKHAFLSGEGGRIRVSWRREDGRLRLTVSDNGVGLPEDV----------DPPARKGLG 459
|
490 500 510
....*....|....*....|....*....|
gi 966513817 492 LYIARDLCEINQASLNvMNREKGCCFTITL 521
Cdd:COG3920 460 LRLIRALVRQLGGTLE-LDRPEGTRVRITF 488
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
422-492 |
4.15e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 43.14 E-value: 4.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAiqhgKD---KTGQVEITIKARQTEQNTQLMVC-------------DTGPGVKESVMDAIFDPFFSTVR 485
Cdd:cd16919 1 LELAILNLAVNA----RDampEGGRLTIETSNQRVDADYALNYRdlipgnyvclevsDTGSGMPAEVLRRAFEPFFTTKE 76
|
....*..
gi 966513817 486 TGYGMGL 492
Cdd:cd16919 77 VGKGTGL 83
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
315-500 |
5.13e-05 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 45.78 E-value: 5.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 315 FSASIAHELRNPLG-------AISHAVQ---------LMGENDTLTE--DDLrlkeliinncHrmnrviknvmQLSRREQ 376
Cdd:PRK10549 243 FMADISHELRTPLAvlrgeleAIQDGVRkftpesvasLQAEVGTLTKlvDDL----------H----------QLSLSDE 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 377 S----QQQVIDLASFLNQ----FKQDFCSHSaCSIQIELPEVplLPFHFDKSQLEQILVILCDNAIQHgKDKTGQVEITi 448
Cdd:PRK10549 303 GalayRKTPVDLVPLLEVaggaFRERFASRG-LTLQLSLPDS--ATVFGDPDRLMQLFNNLLENSLRY-TDSGGSLHIS- 377
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 966513817 449 kARQTEQNTQLMVCDTGPGVKESVMDAIFDPFFSTVRT------GYGMGLYIARDLCE 500
Cdd:PRK10549 378 -AEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSrnrasgGSGLGLAICLNIVE 434
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
315-524 |
6.06e-05 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 45.53 E-value: 6.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 315 FSASIAHELRNPL-GAISHAVQLMGENDTLTEddlrLKELIINNCH---RMNRVIKNVMQLSRREQSQ----QQVIDLAS 386
Cdd:PRK09835 265 FSADIAHEIRTPItNLITQTEIALSQSRSQKE----LEDVLYSNLEeltRMAKMVSDMLFLAQADNNQlipeKKMLDLAD 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 387 -FLNQFkqDFCSHSACSIQIELpevpllpfHF---------DKSQLEQILVILCDNAIQHGKDktGQVeITIKARQTEQN 456
Cdd:PRK09835 341 eVGKVF--DFFEAWAEERGVEL--------RFvgdpcqvagDPLMLRRAISNLLSNALRYTPA--GEA-ITVRCQEVDHQ 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 966513817 457 TQLMVCDTGPGVKESVMDAIFDPFF----STVRT--GYGMGLYIARDLCEINQASLNVMNREKGCCFTITLNQA 524
Cdd:PRK09835 408 VQLVVENPGTPIAPEHLPRLFDRFYrvdpSRQRKgeGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLPRL 481
|
|
| HATPase_Phy-like |
cd16932 |
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana ... |
418-521 |
8.06e-05 |
|
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana Phytochrome A, B, C, D and E; This family includes the histidine kinase-like ATPase (HATPase) domains of plant red/far-red photoreceptors, the phytochromes, and includes the Arabidopsis thaliana phytochrome family phyA-phyE. Following red light absorption, biologically inactive forms of phytochromes convert to active forms, which rapidly convert back to inactive forms upon far-red light irradiation. Phytochromes can be considered as having an N-terminal photosensory region to which a bilin chromophore is bound, and a C-terminal output region, which includes the HATPase domain represented here, and is involved in dimerization and presumably contributes to relaying the light signal to downstream signaling events.
Pssm-ID: 340409 [Multi-domain] Cd Length: 113 Bit Score: 42.26 E-value: 8.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQILVILCDNAIQHGKDKTGQVEITIKARQTE-------QNTQLMVCDTGPGVKESVMDAIFDPffSTVRTGYGM 490
Cdd:cd16932 3 DQIRLQQVLADFLLNAVRFTPSPGGWVEIKVSPTKKQigdgvhvIHLEFRITHPGQGLPEELVQEMFEE--NQWTTQEGL 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 966513817 491 GLYIARDLceinqasLNVMN------REKG-CCFTITL 521
Cdd:cd16932 81 GLSISRKL-------VKLMNgdvrylREAGrSYFLITL 111
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
422-521 |
1.20e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 41.26 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 422 LEQILVILCDNAIQHGkDKTGQVEITIKARQTeqntQLMVCDTGPGVKESVMDAIFDPFF----STVRT--GYGMGLYIA 495
Cdd:cd16939 1 MARALDNLLRNALRYA-HRTVRIALLVSGGRL----TLIVEDDGPGIPAAARERVFEPFVrldpSRDRAtgGFGLGLAIV 75
|
90 100
....*....|....*....|....*..
gi 966513817 496 RDLCEINQASLNVMNREK-GCCFTITL 521
Cdd:cd16939 76 HRVALWHGGHVECDDSELgGACFRLTW 102
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
429-493 |
3.07e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 40.12 E-value: 3.07e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966513817 429 LCDNAIQHGKDK-TGQVEITIKARQTEQNTQLMVCDTGPGVKESVMDAIfdpfFSTVRTGYGMGLY 493
Cdd:cd16924 9 LVENAIQHGLSPlTDKGVVTISALKEDNHVMIEVEDNGRGIDPKVLNIL----GKKPKEGNGIGLY 70
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
429-518 |
3.72e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 40.26 E-value: 3.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 429 LCDNAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF------STVRTGYGMGLYIARDLCEIN 502
Cdd:cd16952 8 LVSNAVKYTPPSD---TITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTGLGLAIVKHVMSRH 84
|
90
....*....|....*..
gi 966513817 503 QASLNVMNRE-KGCCFT 518
Cdd:cd16952 85 DARLLIASELgKGSRFT 101
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
432-521 |
4.95e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 39.68 E-value: 4.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 432 NAIQHGKDKTgqvEITIKARQTEQNTQLMVCDTGPGVKESVMDAIFDPFF----STVRTGYGMGLYIARDLCEINQASLN 507
Cdd:cd16923 11 NAIKYSPENT---RIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIAKAIIELHGGSAS 87
|
90
....*....|....
gi 966513817 508 VMNREKGCCFTITL 521
Cdd:cd16923 88 AEYDDNHDLFKVRL 101
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
429-521 |
9.85e-04 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 38.40 E-value: 9.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 429 LCDNAIQHGKDKTGQVEITIKARQTEQNTQLMVCDTGPGvkesvmdaiFDPFFS-----TVRTGyGMGLYIARDLCEinq 503
Cdd:cd16936 8 AVTNAVRHAYRHDGPGPVRLELDLDPDRLRVEVTDSGPG---------FDPLRPadpdaGLREG-GRGLALIRALMD--- 74
|
90
....*....|....*...
gi 966513817 504 aSLNVMNREKGCCFTITL 521
Cdd:cd16936 75 -EVGYRRTPGGKTVWLEL 91
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
418-521 |
4.92e-03 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 38.33 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 418 DKSQLEQI---LVILCDNAIQH-----------GKDKTGQveITIKARQTEQNTQLMVCDTGPGV--------------- 468
Cdd:cd16916 32 DKSVLEKLadpLTHLLRNAVDHgieapeerlaaGKPPEGT--ITLRAEHQGNQVVIEVSDDGRGIdrekirekaiergli 109
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 966513817 469 ---------KESVMDAIFDPFFSTVRT-----GYGMGLYIARDLCEINQASLNVMNRE-KGCCFTITL 521
Cdd:cd16916 110 tadeaatlsDDEVLNLIFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTIEVESEPgQGTTFTIRL 177
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
171-494 |
9.68e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 38.66 E-value: 9.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 171 AWYLANRVRasETLAVHRSHELASMQRINEYIVERLHSGVIYVDANQTIKLINGAARQFFNCLQT------RDLATI--- 241
Cdd:PRK15053 198 SWFFAAHIR--RQMMGMEPKQIARVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPgrqwlgKPIAEVvrp 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 242 -DQLSPSLAKKYQDylkkIMDNFRPAKTIINDPYLRVhffptqvGTKVAVLIL----LDDMSAVSQQAQQLK--LASLgr 314
Cdd:PRK15053 276 aDFFTEQIDEKRQD----VVANFNGLSVIANREAIRS-------GDDLLGAIIsfrsKDEISTLNAQLTQIKqyVESL-- 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 315 fsASIAHELRNPLGAISHAVQlMGENDtlteddlrlkeliinnchrmnRVIKNVMQLSrreQSQQQVIDlaSFLNQFKQD 394
Cdd:PRK15053 343 --RTLRHEHLNWMSTLNGLLQ-MKEYD---------------------RVLEMVQGES---QAQQQLID--SLREAFADR 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966513817 395 FCS-------HSACSIQIELPEVP-----LLPFHFDKSQLEQILVILCDNAIQHG-KDKTGQVEITIKARQTEQNTQLMV 461
Cdd:PRK15053 394 QVAgllfgkvQRARELGLKMVIVPgsqlsQLPPGLDSTEFAAIVGNLLDNAFEASlRSDEGNKIVELFLSDEGDDVVIEV 473
|
330 340 350
....*....|....*....|....*....|....*..
gi 966513817 462 CDTGPGVKESVMDAIFDPFFSTvRTG----YGMGLYI 494
Cdd:PRK15053 474 ADQGCGVPESLRDKIFEQGVST-RADepgeHGIGLYL 509
|
|
| |
