|
Name |
Accession |
Description |
Interval |
E-value |
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1-602 |
6.46e-156 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 460.04 E-value: 6.46e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 1 MSRMTSFWGLLRAYWVSDRWKEAWALTAAIFLITAFISKTTVWVAEASGHLMNSIVNVNtapvqspLAAVVTNAGVLIIL 80
Cdd:COG4178 1 RSLLRQFWRLARPYWRSEEKWKAWGLLALLLLLTLASVGLNVLLNFWNRDFYDALQARD-------AAAFWQQLGVFALL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 81 ILAkDVLLVGFRHLLSTTLHRKWRKWLNDSFSDALLDrNHTHFHLQQGNGAHlpDNVDQRVQESIKGMTGGAIGLVMGIV 160
Cdd:COG4178 74 AAI-SILLAVYQTYLRQRLQIRWREWLTERLLDRWLS-NRAYYRLQLSGGEI--DNPDQRIAEDIRLFTETTLSLSLGLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 161 GVVLSAFFVGQKLLEISTEVhGLEFLGS----YGGAVLALaviLLYVPLGTLIAIKIGKRLERLNLGMQKAEGSYRGEWT 236
Cdd:COG4178 150 SSVVTLISFIGILWSLSGSL-TFTLGGYsitiPGYMVWAA---LIYAIIGTLLTHLIGRPLIRLNFEQQRREADFRFALV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 237 TLLRRSFQISASEGENVQRTVNNRLYREVDGTWDKLNRFDAAYLAFSQAYGFLSLrIVAYIPGFLPYMSGAVNFRNYVTG 316
Cdd:COG4178 226 RVRENAESIALYRGEAAERRRLRRRFDAVIANWRRLIRRQRNLTFFTTGYGQLAV-IFPILVAAPRYFAGEITLGGLMQA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 317 AELVAAMINDCSWFIQVMPAIANLRANAGRVIGLAQSIESVQEPAEfyARSGVnrfaftHQHPRFGLSVRNLTLMqgPAS 396
Cdd:COG4178 305 ASAFGQVQGALSWFVDNYQSLAEWRATVDRLAGFEEALEAADALPE--AASRI------ETSEDGALALEDLTLR--TPD 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 397 ETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPSVSLKQLVALPRDEGD 476
Cdd:COG4178 375 GRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPAGARVLFLPQRPYLPLGTLREALLYPATAEA 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 477 FNDLAVAAVLHEAGLGEFIERMKDADagnsPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKT 556
Cdd:COG4178 455 FSDAELREALEAVGLGHLAERLDEEA----DWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLRE 530
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 974659840 557 RCPDAIVVSIMHEEKLPTLesgesiFSHVLDI-ANGYVSLIPAHFAA 602
Cdd:COG4178 531 ELPGTTVISVGHRSTLAAF------HDRVLELtGDGSWQLLPAEAPA 571
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
383-590 |
9.97e-54 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 180.81 E-value: 9.97e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQgPASeTPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPSV 462
Cdd:cd03223 1 IELENLSLAT-PDG-RVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGEDLLFLPQRPYLPLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQLVALprdegdfndlavaavlheaglgefiermkdadagnsPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:cd03223 79 TLREQLIY------------------------------------PWDDVLSGGEQQRLAFARLLLHKPKFVFLDEATSAL 122
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 974659840 543 DPASKLRFHTALKTRCpdAIVVSIMHEEKLptlesgESIFSHVLDIAN 590
Cdd:cd03223 123 DEESEDRLYQLLKELG--ITVISVGHRPSL------WKFHDRVLDLDG 162
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
74-576 |
1.04e-27 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 118.40 E-value: 1.04e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 74 AGVLIILILakDVLLVGFRHLLSTTLHRKwrkwLNDSFSDALLDRNhTHFHLQQGNGAHLPDNVdQRVQ--ESI-KGMTG 150
Cdd:COG2274 200 IGLLLALLF--EGLLRLLRSYLLLRLGQR----IDLRLSSRFFRHL-LRLPLSFFESRSVGDLA-SRFRdvESIrEFLTG 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 151 GAIGLVMGIVGVVLSAFFvgqklleistevhglefLGSYGG--AVLALAVILLYVplgtLIAIKIGKRLERLNLGMQKAE 228
Cdd:COG2274 272 SLLTALLDLLFVLIFLIV-----------------LFFYSPplALVVLLLIPLYV----LLGLLFQPRLRRLSREESEAS 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 229 GSYRGEWTTLLR--RSFQISASEGENVQRtvnnrlyrevdgtWDKLNrfdAAYLAFSQAYGFLSLrIVAYIPGFLPYMSG 306
Cdd:COG2274 331 AKRQSLLVETLRgiETIKALGAESRFRRR-------------WENLL---AKYLNARFKLRRLSN-LLSTLSGLLQQLAT 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 307 AVNFrnyVTGA-----------ELVAAMIndcsWFIQVMPAIANLRANAGRVIGLAQSIESVQE----PAEFYArsgvNR 371
Cdd:COG2274 394 VALL---WLGAylvidgqltlgQLIAFNI----LSGRFLAPVAQLIGLLQRFQDAKIALERLDDildlPPEREE----GR 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 372 FAFTHQHPRFGLSVRNLTLmQGPASETPFLRsgVINM--RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQ--- 446
Cdd:COG2274 463 SKLSLPRLKGDIELENVSF-RYPGDSPPVLD--NISLtiKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGidl 539
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 447 ---GASSL-----YVPQEAKFPSVSLKQLVALPRDegDFNDLAVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvL 512
Cdd:COG2274 540 rqiDPASLrrqigVVLQDVFLFSGTIRENITLGDP--DATDEEIIEAARLAGLHDFIEALPMgydtvvGEGGSN-----L 612
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 513 SGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLE 576
Cdd:COG2274 613 SGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAH--RLSTIR 674
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
1-568 |
1.76e-24 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 107.94 E-value: 1.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 1 MSRmtSFWGLLRAYWvsDRWKEAWALTAAIFLITAFISKTTVWVAEASGHLMNSIVNvntapvQSPLAAVVTNAGVLIIL 80
Cdd:COG1132 1 MSK--SPRKLLRRLL--RYLRPYRGLLILALLLLLLSALLELLLPLLLGRIIDALLA------GGDLSALLLLLLLLLGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 81 ILAKDVLLVGFRHLLSTTLHRKWRKWLNDSFsDALLdRNHTHFHLQQGNG---AHLPDNVDQRVQESIKGMTGGAIGLVM 157
Cdd:COG1132 71 ALLRALLSYLQRYLLARLAQRVVADLRRDLF-EHLL-RLPLSFFDRRRTGdllSRLTNDVDAVEQFLAHGLPQLVRSVVT 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 158 GIVGVVLsaffvgqkLLEIStevhgleflgsyggAVLALAVILLyVPLGTLIAIKIGKRLERLNLGMQKAEGSYrgewTT 237
Cdd:COG1132 149 LIGALVV--------LFVID--------------WRLALIVLLV-LPLLLLVLRLFGRRLRKLFRRVQEALAEL----NG 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 238 LLRRSF------QISASEGENVQR--TVNNRLYRevdgTWDKLNRFDAAYLAFSQAYGFLSLRIVAYIpGFLPYMSGAVN 309
Cdd:COG1132 202 RLQESLsgirvvKAFGREERELERfrEANEELRR----ANLRAARLSALFFPLMELLGNLGLALVLLV-GGLLVLSGSLT 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 310 FRNYVTGAELVAAMINDCSWFIQVMPAIANLRANAGRVIGLAQSIESVQEPAEfyarsgvnrfAFTHQHPRFGLSVRNLT 389
Cdd:COG1132 277 VGDLVAFILYLLRLFGPLRQLANVLNQLQRALASAERIFELLDEPPEIPDPPG----------AVPLPPVRGEIEFENVS 346
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 390 LmqGPASETPFLRSgvINM--RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNII--------YPQgaSSL-----YVP 454
Cdd:COG1132 347 F--SYPGDRPVLKD--ISLtiPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILidgvdirdLTL--ESLrrqigVVP 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 455 QEAKFPSVSLKQLVALPRDegDFNDLAVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVMLARILLH 528
Cdd:COG1132 421 QDTFLFSGTIRENIRYGRP--DATDEEVEEAAKAAQAHEFIEALPDgydtvvGERGVN-----LSGGQRQRIAIARALLK 493
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 974659840 529 KPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMH 568
Cdd:COG1132 494 DPPILILDEATSALDTETEALIQEALERLMKGRTTIVIAH 533
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
383-568 |
1.91e-23 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 98.73 E-value: 1.91e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLmqgPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---PQGASS--------L 451
Cdd:COG4619 1 LELEGLSF---RVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLdgkPLSAMPppewrrqvA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 YVPQEAKFPSVSLKQLVALPRD--EGDFNDLAVAAVLHEAGLGEFIermKDADAGNspwdmvLSGGQKQKVMLARILLHK 529
Cdd:COG4619 78 YVPQEPALWGGTVRDNLPFPFQlrERKFDRERALELLERLGLPPDI---LDKPVER------LSGGERQRLALIRALLLQ 148
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 974659840 530 PSIIFLDEATGALDPASKLRFHTALKTRC--PDAIVVSIMH 568
Cdd:COG4619 149 PDVLLLDEPTSALDPENTRRVEELLREYLaeEGRAVLWVSH 189
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
418-587 |
5.75e-21 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 90.13 E-value: 5.75e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIiypqgasslyvpqeaKFPSVSLKQLvalprdegDFNDL--AVAAVLHEAGLgeFi 495
Cdd:cd03228 35 GPSGSGKSTLLKLLLRLYDPTSGEI---------------LIDGVDLRDL--------DLESLrkNIAYVPQDPFL--F- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 496 ermkdadaGNSPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTL 575
Cdd:cd03228 89 --------SGTIRENILSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEALRALAKGKTVIVIAH--RLSTI 158
|
170
....*....|..
gi 974659840 576 ESGESIFshVLD 587
Cdd:cd03228 159 RDADRII--VLD 168
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
152-591 |
5.95e-20 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 93.68 E-value: 5.95e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 152 AIGLVMGIVGVVLSAFFVGQklleistevhgleflgsyGGAVLALAVILLYVpLGTLIAIKIGKRLERlnlGMQKAEGSY 231
Cdd:COG4987 137 LVALLVILAAVAFLAFFSPA------------------LALVLALGLLLAGL-LLPLLAARLGRRAGR---RLAAARAAL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 232 RGEWTTLLR--RSFQISASEGENVQRtvnnrlYREVDGTWDKLNRFDAAYLAFSQAY-GFLSLRIVAYIPGFLPYMSGAv 308
Cdd:COG4987 195 RARLTDLLQgaAELAAYGALDRALAR------LDAAEARLAAAQRRLARLSALAQALlQLAAGLAVVAVLWLAAPLVAA- 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 309 nfrNYVTGAELV----AAMindcSWFIQVMP---AIANL---RANAGRVIGLAQSIESVQEPAEFYARSGvnrfafthqh 378
Cdd:COG4987 268 ---GALSGPLLAllvlAAL----ALFEALAPlpaAAQHLgrvRAAARRLNELLDAPPAVTEPAEPAPAPG---------- 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 379 pRFGLSVRNLTLMQgPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL- 451
Cdd:COG4987 331 -GPSLELEDVSFRY-PGAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSItlggvdLRDLDEDDLr 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 ----YVPQEAKFPSVSLKQLVALPRDEGDfnDLAVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVM 521
Cdd:COG4987 409 rriaVVPQRPHLFDTTLRENLRLARPDAT--DEELWAALERVGLGDWLAALPDgldtwlGEGGRR-----LSGGERRRLA 481
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 522 LARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHEeklptlESGESIFSHVLDIANG 591
Cdd:COG4987 482 LARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHR------LAGLERMDRILVLEDG 545
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
409-568 |
2.37e-19 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 91.74 E-value: 2.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL----------YVPQEAKFPSVSLKQLVALPRDEGDf 477
Cdd:COG4988 361 PPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSIlINGVDLSDLdpaswrrqiaWVPQNPYLFAGTIRENLRLGRPDAS- 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 nDLAVAAVLHEAGLGEFIERMKDadaGnspWDMV-------LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRF 550
Cdd:COG4988 440 -DEELEAALEAAGLDEFVAALPD---G---LDTPlgeggrgLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEI 512
|
170
....*....|....*...
gi 974659840 551 HTALKTRCPDAIVVSIMH 568
Cdd:COG4988 513 LQALRRLAKGRTVILITH 530
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
394-568 |
4.74e-19 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 86.10 E-value: 4.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 394 PASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSL-----------YVPQEAKFPSV 462
Cdd:cd03245 13 PNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQldpadlrrnigYVPQDVTLFYG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQLVALPRDEGDfnDLAVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLD 536
Cdd:cd03245 93 TLRDNITLGAPLAD--DERILRAAELAGVTDFVNKHPNgldlqiGERGRG-----LSGGQRQAVALARALLNDPPILLLD 165
|
170 180 190
....*....|....*....|....*....|..
gi 974659840 537 EATGALDPASKLRFHTALKTRCPDAIVVSIMH 568
Cdd:cd03245 166 EPTSAMDMNSEERLKERLRQLLGDKTLIIITH 197
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
384-591 |
5.93e-18 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 81.14 E-value: 5.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 384 SVRNLTLMQGpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPSVS 463
Cdd:cd00267 1 EIENLSFRYG---GRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 464 LKQLvalprdegdfndlavaavlheaglgefiermkdadagnspwdmvlSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:cd00267 78 VPQL---------------------------------------------SGGQRQRVALARALLLNPDLLLLDEPTSGLD 112
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 974659840 544 PASKLRFHTALKTRCPD-AIVVSIMHEeklptLESGESIFSHVLDIANG 591
Cdd:cd00267 113 PASRERLLELLRELAEEgRTVIIVTHD-----PELAELAADRVIVLKDG 156
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
418-572 |
5.97e-18 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 83.75 E-value: 5.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQEAK------------FPSVSLKQLV----ALPRDEGDFNDLA 481
Cdd:COG4555 34 GPNGAGKTTLLRMLAGLLKPDSGSILI-DGEDVRKEPREARrqigvlpderglYDRLTVRENIryfaELYGLFDEELKKR 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 482 VAAVLHEAGLGEFIERMkdadAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKT----- 556
Cdd:COG4555 113 IEELIELLGLEEFLDRR----VGE------LSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRAlkkeg 182
|
170
....*....|....*....
gi 974659840 557 RCpdaIVVS--IMHE-EKL 572
Cdd:COG4555 183 KT---VLFSshIMQEvEAL 198
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
383-569 |
7.36e-18 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 83.55 E-value: 7.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGA--SSL--------- 451
Cdd:COG1120 2 LEAENLSVGYG---GRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLL-DGRdlASLsrrelarri 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 -YVPQEAKFP-SVSLKQLVALPR----------DEGDfnDLAVAAVLHEAGLGEFIERmkdadagnsPWDMvLSGGQKQK 519
Cdd:COG1120 78 aYVPQEPPAPfGLTVRELVALGRyphlglfgrpSAED--REAVEEALERTGLEHLADR---------PVDE-LSGGERQR 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 974659840 520 VMLARILLHKPSIIFLDEATGALDPASKLRFHTALK--TRCPDAIVVSIMHE 569
Cdd:COG1120 146 VLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRrlARERGRTVVMVLHD 197
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
407-539 |
1.81e-17 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 79.61 E-value: 1.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 407 NMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL-----YVPQEAK-FPSVSLKQLVALPRDE 474
Cdd:pfam00005 7 TLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTIlldgqdLTDDERKSLrkeigYVFQDPQlFPRLTVRENLRLGLLL 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 475 GDFNDLAVAAVLHEAglgefIERMKDADAGNSPWDMV---LSGGQKQKVMLARILLHKPSIIFLDEAT 539
Cdd:pfam00005 87 KGLSKREKDARAEEA-----LEKLGLGDLADRPVGERpgtLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
418-586 |
2.07e-17 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 81.43 E-value: 2.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNII---YPQGASSL---YVPQ----EAKFPsVSLKQLVALPRDE--GDFNDL----- 480
Cdd:cd03235 32 GPNGAGKSTLLKAILGLLKPTSGSIRvfgKPLEKERKrigYVPQrrsiDRDFP-ISVRDVVLMGLYGhkGLFRRLskadk 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 481 -AVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCP 559
Cdd:cd03235 111 aKVDEALERVGLSELADRQIGE----------LSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRR 180
|
170 180
....*....|....*....|....*...
gi 974659840 560 DAI-VVSIMHEeklptLESGESIFSHVL 586
Cdd:cd03235 181 EGMtILVVTHD-----LGLVLEYFDRVL 203
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
418-555 |
4.50e-17 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 80.90 E-value: 4.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY----PQGASSL--YVPQEAK----FPsVSLKQLVALPRD--EGDFNDL----- 480
Cdd:COG1121 39 GPNGAGKSTLLKAILGLLPPTSGTVRLfgkpPRRARRRigYVPQRAEvdwdFP-ITVRDVVLMGRYgrRGLFRRPsradr 117
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 481 -AVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALK 555
Cdd:COG1121 118 eAVDEALERVGLEDLADRPIGE----------LSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLR 183
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
409-555 |
1.18e-16 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 79.30 E-value: 1.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY------PQGASSL-----YVPQEAK----FPSV------SLKQL 467
Cdd:COG1122 25 EKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVdgkditKKNLRELrrkvgLVFQNPDdqlfAPTVeedvafGPENL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 468 vALPRDEGDfndLAVAAVLHEAGLGEFIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:COG1122 105 -GLPREEIR---ERVEEALELVGLEHLADR--------PPHE--LSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGR 170
|
....*...
gi 974659840 548 LRFHTALK 555
Cdd:COG1122 171 RELLELLK 178
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
409-569 |
1.68e-16 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 77.86 E-value: 1.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpqGASSLyvpqeAKFPSVSLKQLVALprdegdfndlaVAAVLHE 488
Cdd:cd03214 23 EAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILL--DGKDL-----ASLSPKELARKIAY-----------VPQALEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 489 AGLGEFIERmkdadagnsPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALK--TRCPDAIVVSI 566
Cdd:cd03214 85 LGLAHLADR---------PFNE-LSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLELLRrlARERGKTVVMV 154
|
...
gi 974659840 567 MHE 569
Cdd:cd03214 155 LHD 157
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
418-572 |
3.27e-16 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 78.18 E-value: 3.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL----YVPQEAKF-PSVSLKQLVA-------LPRDEgdfND 479
Cdd:COG1131 33 GPNGAGKTTTIRMLLGLLRPTSGEVrvlgedVARDPAEVRrrigYVPQEPALyPDLTVRENLRffarlygLPRKE---AR 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 480 LAVAAVLHEAGLGEFIERMkdadAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCP 559
Cdd:COG1131 110 ERIDELLELFGLTDAADRK----VGT------LSGGMKQRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAA 179
|
170
....*....|....*...
gi 974659840 560 D--AIVVS--IMHE-EKL 572
Cdd:COG1131 180 EgkTVLLSthYLEEaERL 197
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
418-591 |
5.93e-16 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 75.90 E-value: 5.93e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQEAKfpsvslKQLVALPRDEGDFNDLavaavlheaglgefier 497
Cdd:cd03230 33 GPNGAGKTTLIKIILGLLKPDSGEIKV-LGKDIKKEPEEVK------RRIGYLPEEPSLYENL----------------- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 498 mkdadagnSPWDMV-LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPD--AIVVS--IMHEekl 572
Cdd:cd03230 89 --------TVRENLkLSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKEgkTILLSshILEE--- 157
|
170
....*....|....*....
gi 974659840 573 ptlesGESIFSHVLDIANG 591
Cdd:cd03230 158 -----AERLCDRVAILNNG 171
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
383-547 |
7.28e-16 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 77.16 E-value: 7.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTL-MQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY--------------PQG 447
Cdd:cd03257 2 LEVKNLSVsFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFdgkdllklsrrlrkIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 448 ASSLYVPQEakfPSVSL-------KQL-----VALPRDEGDFNDLAVAAVLHEAGLGEFIERMKDADagnspwdmvLSGG 515
Cdd:cd03257 82 KEIQMVFQD---PMSSLnprmtigEQIaeplrIHGKLSKKEARKEAVLLLLVGVGLPEEVLNRYPHE---------LSGG 149
|
170 180 190
....*....|....*....|....*....|..
gi 974659840 516 QKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:cd03257 150 QRQRVAIARALALNPKLLIADEPTSALDVSVQ 181
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
384-556 |
7.29e-16 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 76.74 E-value: 7.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 384 SVRNLTLMQgPASETPFLRSgvINM--RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---PQGASSL------- 451
Cdd:cd03225 1 ELKNLSFSY-PDGARPALDD--ISLtiKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVdgkDLTKLSLkelrrkv 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 -YVPQ--EAKF--PSV------SLKQLvALPRDEGDfndLAVAAVLHEAGLGEFIERmkdadagnSPWDmvLSGGQKQKV 520
Cdd:cd03225 78 gLVFQnpDDQFfgPTVeeevafGLENL-GLPEEEIE---ERVEEALELVGLEGLRDR--------SPFT--LSGGQKQRV 143
|
170 180 190
....*....|....*....|....*....|....*.
gi 974659840 521 MLARILLHKPSIIFLDEATGALDPASKLRFHTALKT 556
Cdd:cd03225 144 AIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKK 179
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
21-544 |
1.00e-15 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 80.56 E-value: 1.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 21 KEAWALTAAIFLItafISKT--TVWVAEASGHLMNSIVNVNTAPVQSPL--------AAVVTNAgvLIILILAKdvLLVG 90
Cdd:TIGR00954 93 KETGLLILIAFLL---VSRTylSVYVATLDGQIESSIVRRSPRNFAWILfkwfliapPASFINS--AIKYLLKE--LKLR 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 91 FRHLLSTTLHRKWRKwlndsfsdalldrNHTHFHLqqGNGAHLPDNVDQRVQESIKGMTGGAIGLVMGIVGVVLSAFFVG 170
Cdd:TIGR00954 166 FRVRLTRYLYSKYLS-------------GFTFYKV--SNLDSRIQNPDQLLTQDVEKFCDSVVELYSNLTKPILDVILYS 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 171 QKLLEIstevhglefLGSYGGAVlalavILLYVPLGTLIAIKIGKRLERLNLGMQKAEGSYRGEWTTLLRRSFQISASEG 250
Cdd:TIGR00954 231 FKLLTA---------LGSVGPAG-----LFAYLFATGVVLTKLRPPIGKLTVEEQALEGEYRYVHSRLIMNSEEIAFYQG 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 251 ENVQRTvnnrlyrEVDGTWDKLNRFDAAYLAFSQAYGFLSLRIVAYIPGFLPYMSGAVNF-----------------RNY 313
Cdd:TIGR00954 297 NKVEKE-------TVMSSFYRLVEHLNLIIKFRFSYGFLDNIVAKYTWSAVGLVAVSIPIfdkthpaflemseeelmQEF 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 314 VTGAELVAAMINDCSWFIQVMPAIANLRANAGRVIGLAQSIESVQ-----EPAEFYARSGVNRFAFTHQHPRFGLSVRNL 388
Cdd:TIGR00954 370 YNNGRLLLKAADALGRLMLAGRDMTRLAGFTARVDTLLQVLDDVKsgnfkRPRVEEIESGREGGRNSNLVPGRGIVEYQD 449
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 389 TLMQ-------GPASETpFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPS 461
Cdd:TIGR00954 450 NGIKfeniplvTPNGDV-LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQRPYMTL 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 VSLKQLVALPRD-----EGDFNDLAVAAVLHEAGLGEFIERMKDADAGNSpWDMVLSGGQKQKVMLARILLHKPSIIFLD 536
Cdd:TIGR00954 529 GTLRDQIIYPDSsedmkRRGLSDKDLEQILDNVQLTHILEREGGWSAVQD-WMDVLSGGEKQRIAMARLFYHKPQFAILD 607
|
....*...
gi 974659840 537 EATGALDP 544
Cdd:TIGR00954 608 ECTSAVSV 615
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
383-575 |
1.25e-15 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 76.38 E-value: 1.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASEtPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---------PQGASSLY- 452
Cdd:cd03244 3 IEFKNVSLRYRPNLP-PVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIdgvdiskigLHDLRSRIs 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 453 -VPQEAKFPSVSLKQLVAlPRDEgdFNDLAVAAVLHEAGLGEFIERMKDADagnspwDMV-------LSGGQKQKVMLAR 524
Cdd:cd03244 82 iIPQDPVLFSGTIRSNLD-PFGE--YSDEELWQALERVGLKEFVESLPGGL------DTVveeggenLSVGQRQLLCLAR 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 974659840 525 ILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTL 575
Cdd:cd03244 153 ALLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAH--RLDTI 201
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
198-587 |
2.27e-15 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 79.38 E-value: 2.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 198 VILLYVPLGTLIAIKIGKRLERLNLGMQKAEG--SYRGEWTTLLRRSFQISASEGENVQR--TVNNRLYREVDgtwdKLN 273
Cdd:TIGR02203 159 IVVVMLPVLSILMRRVSKRLRRISKEIQNSMGqvTTVAEETLQGYRVVKLFGGQAYETRRfdAVSNRNRRLAM----KMT 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 274 RFDAAYLAFSQAYGFLSLRIVAYIPGFLPYMsgavnfrNYVTGAELVAAMindcSWFIQVMPAI---ANLRANAGRVIGL 350
Cdd:TIGR02203 235 SAGSISSPITQLIASLALAVVLFIALFQAQA-------GSLTAGDFTAFI----TAMIALIRPLkslTNVNAPMQRGLAA 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 351 AQSI-ESVQEPAEfyarsgVNRFAFTHQHPRFGLSVRNLTLmQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIK 429
Cdd:TIGR02203 304 AESLfTLLDSPPE------KDTGTRAIERARGDVEFRNVTF-RYPGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVN 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 430 ALNGLWPYGTGNIIYPQGASSLYVPQE--AKFPSVSlkQLVALPRDE----------GDFNDLAVAAVLHEAGLGEFIER 497
Cdd:TIGR02203 377 LIPRFYEPDSGQILLDGHDLADYTLASlrRQVALVS--QDVVLFNDTianniaygrtEQADRAEIERALAAAYAQDFVDK 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 498 MKDA-------DAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHee 570
Cdd:TIGR02203 455 LPLGldtpigeNGVL------LSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQGRTTLVIAH-- 526
|
410
....*....|....*..
gi 974659840 571 KLPTLESGESIFshVLD 587
Cdd:TIGR02203 527 RLSTIEKADRIV--VMD 541
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
386-587 |
3.21e-15 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 75.20 E-value: 3.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 386 RNLTLMQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLY-----------VP 454
Cdd:cd03248 15 QNVTFAYPTRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYehkylhskvslVG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 455 QEAKFPSVSLKQLVALPRDEGDFNDLAVAAVlhEAGLGEFIERMK---DADAGNSpwDMVLSGGQKQKVMLARILLHKPS 531
Cdd:cd03248 95 QEPVLFARSLQDNIAYGLQSCSFECVKEAAQ--KAHAHSFISELAsgyDTEVGEK--GSQLSGGQKQRVAIARALIRNPQ 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 532 IIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLESGESIFshVLD 587
Cdd:cd03248 171 VLILDEATSALDAESEQQVQQALYDWPERRTVLVIAH--RLSTVERADQIL--VLD 222
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
418-554 |
3.54e-15 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 74.82 E-value: 3.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY------PQGASSLYVPQE-AKFPSVSLKQLVALP----------RDEgdfndl 480
Cdd:cd03293 37 GPSGCGKSTLLRIIAGLERPTSGEVLVdgepvtGPGPDRGYVFQQdALLPWLTVLDNVALGlelqgvpkaeARE------ 110
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 481 AVAAVLHEAGLGEFIERMkdadagnsPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTAL 554
Cdd:cd03293 111 RAEELLELVGLSGFENAY--------PHQ--LSGGMRQRVALARALAVDPDVLLLDEPFSALDALTREQLQEEL 174
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
383-593 |
3.59e-15 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 73.79 E-value: 3.59e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQgPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIiypqgasslyvpqeaKFPSV 462
Cdd:cd03246 1 LEVENVSFRY-PGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRV---------------RLDGA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQLvalprDEGDFNDLaVAAVLHEaglgefIERMKDADAGNspwdmVLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:cd03246 65 DISQW-----DPNELGDH-VGYLPQD------DELFSGSIAEN-----ILSGGQRQRLGLARALYGNPRILVLDEPNSHL 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 974659840 543 DPASKLRFHTALK-TRCPDAIVVSIMHeeKLPTLESGESIfshvLDIANGYV 593
Cdd:cd03246 128 DVEGERALNQAIAaLKAAGATRIVIAH--RPETLASADRI----LVLEDGRV 173
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
379-572 |
4.92e-15 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 78.10 E-value: 4.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 379 PRFGLSVRNLTLMQGpaSETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL- 451
Cdd:TIGR02857 318 PASSLEFSGVSVAYP--GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIavngvpLADADADSWr 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 ----YVPQEAKFPSVSLKQLVALPRDEGDfnDLAVAAVLHEAGLGEFIE---RMKDADAGNSPwdMVLSGGQKQKVMLAR 524
Cdd:TIGR02857 396 dqiaWVPQHPFLFAGTIAENIRLARPDAS--DAEIREALERAGLDEFVAalpQGLDTPIGEGG--AGLSGGQAQRLALAR 471
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 974659840 525 ILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHEEKL 572
Cdd:TIGR02857 472 AFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTHRLAL 519
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
383-568 |
6.87e-15 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 77.64 E-value: 6.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLmQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYG---TGNIIYpQGASSL-------- 451
Cdd:COG1123 5 LEVRDLSV-RYPGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLL-DGRDLLelsealrg 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 ----YVPQE---AKFPSVSLKQLV------ALPRDEGDfndLAVAAVLHEAGLGEFIERmkdadagnSPWDmvLSGGQKQ 518
Cdd:COG1123 83 rrigMVFQDpmtQLNPVTVGDQIAealenlGLSRAEAR---ARVLELLEAVGLERRLDR--------YPHQ--LSGGQRQ 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 974659840 519 KVMLARILLHKPSIIFLDEATGALDPASKLRFHTALK--TRCPDAIVVSIMH 568
Cdd:COG1123 150 RVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRelQRERGTTVLLITH 201
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
379-568 |
8.59e-15 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 77.39 E-value: 8.59e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 379 PRFGLSVRNLTLMQgPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQ-----G 447
Cdd:TIGR01842 313 PEGHLSVENVTIVP-PGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVrldgadLKQWdretfG 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 448 ASSLYVPQEAKFPSVSLKQLVALPRDEGDFNDLAVAAVLheAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVM 521
Cdd:TIGR01842 392 KHIGYLPQDVELFPGTVAENIARFGENADPEKIIEAAKL--AGVHELILRLPDgydtviGPGGAT-----LSGGQRQRIA 464
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 974659840 522 LARILLHKPSIIFLDEATGALDPASKLRFHTALKT-RCPDAIVVSIMH 568
Cdd:TIGR01842 465 LARALYGDPKLVVLDEPNSNLDEEGEQALANAIKAlKARGITVVVITH 512
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
410-558 |
1.65e-14 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 72.51 E-value: 1.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 410 AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASS----------LYV-PQEAKFPSVSLKQLVAL--PRDEGD 476
Cdd:COG4133 27 AGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRdaredyrrrlAYLgHADGLKPELTVRENLRFwaALYGLR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 477 FNDLAVAAVLHEAGLGEFIermkDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKT 556
Cdd:COG4133 107 ADREAIDEALEAVGLAGLA----DLPVRQ------LSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAA 176
|
..
gi 974659840 557 RC 558
Cdd:COG4133 177 HL 178
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
406-555 |
3.19e-14 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 72.26 E-value: 3.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYP-QGASSL----------YVPQEAKFPSVSLKQLVALPRDE 474
Cdd:cd03254 24 FSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDgIDIRDIsrkslrsmigVVLQDTFLFSGTIMENIRLGRPN 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 475 GDfnDLAVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKL 548
Cdd:cd03254 104 AT--DEEVIEAAKEAGAHDFIMKLPNgydtvlGENGGN-----LSQGERQLLAIARAMLRDPKILILDEATSNIDTETEK 176
|
....*..
gi 974659840 549 RFHTALK 555
Cdd:cd03254 177 LIQEALE 183
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
154-568 |
3.40e-14 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 75.47 E-value: 3.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 154 GLVMGIVGVVLSAFFVGqklleistevhGLEFLGSYGGAVLA--LAVILLYVPLGTLIAIKIGKRLErlnlgmQKAEGSY 231
Cdd:TIGR02868 130 VIVPAGVALVVGAAAVA-----------AIAVLSVPAALILAagLLLAGFVAPLVSLRAARAAEQAL------ARLRGEL 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 232 RGEWTTLLRRSFQISASEGENVQRtvnnRLYREVDGTWDKLNRFDAAYLAFSQAYGFLS------LRIVAYIPGflpYMS 305
Cdd:TIGR02868 193 AAQLTDALDGAAELVASGALPAAL----AQVEEADRELTRAERRAAAATALGAALTLLAaglavlGALWAGGPA---VAD 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 306 GAVnfrnyvTGAELVAAMINDCSWFiQVMPAIANLRANAGRVIGLAQSIESVQEPAEFYARSGVNRfAFTHQHPRFGLSV 385
Cdd:TIGR02868 266 GRL------APVTLAVLVLLPLAAF-EAFAALPAAAQQLTRVRAAAERIVEVLDAAGPVAEGSAPA-AGAVGLGKPTLEL 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 386 RNLTLMQGPASetPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNII--------YPQGASS---LYVP 454
Cdd:TIGR02868 338 RDLSAGYPGAP--PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTldgvpvssLDQDEVRrrvSVCA 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 455 QEAKFPSVSLKQLVALPRdeGDFNDLAVAAVLHEAGLGEFIERMKD-ADAGNSPWDMVLSGGQKQKVMLARILLHKPSII 533
Cdd:TIGR02868 416 QDAHLFDTTVRENLRLAR--PDATDEELWAALERVGLADWLRALPDgLDTVLGEGGARLSGGERQRLALARALLADAPIL 493
|
410 420 430
....*....|....*....|....*....|....*
gi 974659840 534 FLDEATGALDPASKLRFHTALKTRCPDAIVVSIMH 568
Cdd:TIGR02868 494 LLDEPTEHLDAETADELLEDLLAALSGRTVVLITH 528
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
406-564 |
1.06e-13 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 70.30 E-value: 1.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIY-MRGESGSGKTSFIKALNGLWPYGTGNI--------IYPQGASSL--YVPQEAKF-PSVS----LKQLVA 469
Cdd:cd03264 19 VSLTLGPGMYgLLGPNGAGKTTLMRILATLTPPSSGTIridgqdvlKQPQKLRRRigYLPQEFGVyPNFTvrefLDYIAW 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 LPRDEGDFNDLAVAAVLHEAGLGEFI-ERMKDadagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKL 548
Cdd:cd03264 99 LKGIPSKEVKARVDEVLELVNLGDRAkKKIGS-----------LSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERI 167
|
170
....*....|....*.
gi 974659840 549 RFHTALKTRCPDAIVV 564
Cdd:cd03264 168 RFRNLLSELGEDRIVI 183
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
418-544 |
1.37e-13 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 73.40 E-value: 1.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY------PQGASSL--------YVPQ---EAKFPSVSLKQLVALP---RDEGDF 477
Cdd:COG1123 298 GESGSGKSTLARLLLGLLRPTSGSILFdgkdltKLSRRSLrelrrrvqMVFQdpySSLNPRMTVGDIIAEPlrlHGLLSR 377
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 NDLA--VAAVLHEAGLG-EFIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG1123 378 AERRerVAELLERVGLPpDLADR--------YPHE--LSGGQRQRVAIARALALEPKLLILDEPTSALDV 437
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
394-587 |
1.45e-13 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 70.34 E-value: 1.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 394 PASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL-----YVPQEAKFPSV 462
Cdd:cd03251 11 PGDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRIlidghdVRDYTLASLrrqigLVSQDVFLFND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQLVALPRDEGDfnDLAVAAVLHEAGLGEFIERMKDA------DAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLD 536
Cdd:cd03251 91 TVAENIAYGRPGAT--REEVEEAARAANAHEFIMELPEGydtvigERGVK-----LSGGQRQRIAIARALLKDPPILILD 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 974659840 537 EATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLESGESIFshVLD 587
Cdd:cd03251 164 EATSALDTESERLVQAALERLMKNRTTFVIAH--RLSTIENADRIV--VLE 210
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
383-555 |
1.55e-13 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 70.21 E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASETPFLRSGV-INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSLYVPQEAKF- 459
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVsLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVrVDGTDISKLSEKELAAFr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 460 --------------PSVSLKQLVALP----RDEGDFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVM 521
Cdd:cd03255 81 rrhigfvfqsfnllPDLTALENVELPlllaGVPKKERRERAEELLERVGLGDRLNHYPSE----------LSGGQQQRVA 150
|
170 180 190
....*....|....*....|....*....|....
gi 974659840 522 LARILLHKPSIIFLDEATGALDPASKLRFHTALK 555
Cdd:cd03255 151 IARALANDPKIILADEPTGNLDSETGKEVMELLR 184
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
408-581 |
2.62e-13 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 69.82 E-value: 2.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 408 MRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNII---YPQGASSL--------YVPQEAKFPSVSLKQLVALPRDEGD 476
Cdd:cd03252 25 IKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLvdgHDLALADPawlrrqvgVVLQENVLFNRSIRDNIALADPGMS 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 477 FNDLAVAAVLheAGLGEFIERMKDAdagnspWDMV-------LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLR 549
Cdd:cd03252 105 MERVIEAAKL--AGAHDFISELPEG------YDTIvgeqgagLSGGQRQRIAIARALIHNPRILIFDEATSALDYESEHA 176
|
170 180 190
....*....|....*....|....*....|..
gi 974659840 550 FHTALKTRCPDAIVVSIMHeeKLPTLESGESI 581
Cdd:cd03252 177 IMRNMHDICAGRTVIIIAH--RLSTVKNADRI 206
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
381-544 |
3.56e-13 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 69.22 E-value: 3.56e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 381 FGLSVRNLtlmqgpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALnglwpygTGNIIYPQGASSLYVPQEAKFP 460
Cdd:COG2401 34 FGVELRVV--------ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLL-------AGALKGTPVAGCVDVPDNQFGR 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 461 SVSLkqLVALPRDeGDFNDlaVAAVLHEAGLGefiermkDADAGNSPWDmVLSGGQKQKVMLARILLHKPSIIFLDEATG 540
Cdd:COG2401 99 EASL--IDAIGRK-GDFKD--AVELLNAVGLS-------DAVLWLRRFK-ELSTGQKFRFRLALLLAERPKLLVIDEFCS 165
|
....
gi 974659840 541 ALDP 544
Cdd:COG2401 166 HLDR 169
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
397-593 |
4.31e-13 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 69.11 E-value: 4.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 397 ETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---------PQGASSL--YVPQEAKFPSVSLK 465
Cdd:cd03249 15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLdgvdirdlnLRWLRSQigLVSQEPVLFDGTIA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 466 QLVALPRDEGDfnDLAVAAVLHEAGLGEFIerMKDADAGNSpwdMV------LSGGQKQKVMLARILLHKPSIIFLDEAT 539
Cdd:cd03249 95 ENIRYGKPDAT--DEEVEEAAKKANIHDFI--MSLPDGYDT---LVgergsqLSGGQKQRIAIARALLRNPKILLLDEAT 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 974659840 540 GALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLESGESIFshVLDiaNGYV 593
Cdd:cd03249 168 SALDAESEKLVQEALDRAMKGRTTIVIAH--RLSTIRNADLIA--VLQ--NGQV 215
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
383-544 |
6.08e-13 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 69.06 E-value: 6.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASETPFLRSGV-INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---PQGASSL------- 451
Cdd:COG1124 2 LEVRNLSVSYGQGGRRVPVLKDVsLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFdgrPVTRRRRkafrrrv 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 -YVPQEAkFPSV----SLKQLVALP-RDEGDFNDLA-VAAVLHEAGLG-EFIERMKDAdagnspwdmvLSGGQKQKVMLA 523
Cdd:COG1124 82 qMVFQDP-YASLhprhTVDRILAEPlRIHGLPDREErIAELLEQVGLPpSFLDRYPHQ----------LSGGQRQRVAIA 150
|
170 180
....*....|....*....|.
gi 974659840 524 RILLHKPSIIFLDEATGALDP 544
Cdd:COG1124 151 RALILEPELLLLDEPTSALDV 171
|
|
| ABC_membrane_2 |
pfam06472 |
ABC transporter transmembrane region 2; This domain covers the transmembrane of a small family ... |
10-304 |
9.42e-13 |
|
ABC transporter transmembrane region 2; This domain covers the transmembrane of a small family of ABC transporters and shares sequence similarity with pfam00664. Mutations in this domain in Swiss:P28288 are believed responsible for Zellweger Syndrome-2; mutations in Swiss:P33897 are responsible for recessive X-linked adrenoleukodystrophy. A Saccharomyces cerevisiae homolog is involved in the import of long-chain fatty acids.
Pssm-ID: 399466 Cd Length: 269 Bit Score: 68.79 E-value: 9.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 10 LLRAYWVSDRWKEAWALTAAIFLItafISKT--TVWVAEASGHLMNSIVNVNtapvqspLAAVVTNAGVLIILILAKDVL 87
Cdd:pfam06472 1 LLKILFPRWFSKEAGLLLALAALL---VLRTflSVLVAQLDGQIVKALVAKN-------GRGFIRLLLKWALLAVPASFV 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 88 LVGFRHLLSTtLHRKWRKWLNDSFSDALLDrNHTHFHLQqgNGAHLPDNVDQRVQESIKGMTGGAIGLVMGIVGVVLSAF 167
Cdd:pfam06472 71 NSALKYLTQR-LALRFRTRLTRHLHDEYLK-GRTYYKMS--NLDGRIDNPDQRITQDVEKFCSSLSDLYSNLLKPILDII 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 168 FVGQKLLEISTEvhgleflgsyggavLALAVILLYVPLGTLIAIKIGKRLERLNLGMQKAEGSYRGEWTTLLRRSFQISA 247
Cdd:pfam06472 147 LFTFRLWRLSGW--------------RGPAILFLYVLLSAVILRRLSPPFGKLVAEEQKLEGEFRYLHSRLITNAEEIAF 212
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 248 SEGENVQRTVNNRLYREVDGTWDKlnrfdaaYLAFSQAYGFLSLRIVAYIPGFLPYM 304
Cdd:pfam06472 213 YRGEKREKKQLQRSFKSLIDHMRR-------ILRRRLWYGFIEDFVLKYTWSILGYV 262
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
418-550 |
9.80e-13 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 67.98 E-value: 9.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYG-----TGNI-IYPQGASSLYVP------------QEAK-FPSvSLKQLVAL-PRDEG-- 475
Cdd:cd03260 33 GPSGCGKSTLLRLLNRLNDLIpgapdEGEVlLDGKDIYDLDVDvlelrrrvgmvfQKPNpFPG-SIYDNVAYgLRLHGik 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 476 --DFNDLAVAAVLHEAGLGEfieRMKDADAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRF 550
Cdd:cd03260 112 lkEELDERVEEALRKAALWD---EVKDRLHALG-----LSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKI 180
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
410-549 |
1.05e-12 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 67.77 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 410 AGDWIYMRGESGSGKTSFIKALNG-LWPYgTGNIIY-------------PQ-----GasslYVPQEAKF-PSVSLKQLVA 469
Cdd:COG2884 27 KGEFVFLTGPSGAGKSTLLKLLYGeERPT-SGQVLVngqdlsrlkrreiPYlrrriG----VVFQDFRLlPDRTVYENVA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 LP-----RDEGDFNDlAVAAVLHEAGLGEFIERMkdadagnsPwdMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG2884 102 LPlrvtgKSRKEIRR-RVREVLDLVGLSDKAKAL--------P--HELSGGEQQRVAIARALVNRPELLLADEPTGNLDP 170
|
....*
gi 974659840 545 ASKLR 549
Cdd:COG2884 171 ETSWE 175
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
406-556 |
2.61e-12 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 65.67 E-value: 2.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGL-WP------------YGTGNIIYPQGASSLYVPQE-AKFPSVSLKQLVALP 471
Cdd:cd03229 21 LNIEAGEIVALLGPSGSGKSTLLRCIAGLeEPdsgsilidgedlTDLEDELPPLRRRIGMVFQDfALFPHLTVLENIALG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 472 rdegdfndlavaavlheaglgefiermkdadagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:cd03229 101 ----------------------------------------LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVR 140
|
....*
gi 974659840 552 TALKT 556
Cdd:cd03229 141 ALLKS 145
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
409-549 |
3.88e-12 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 66.32 E-value: 3.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVP----------QEAK-FPSVSLKQLVALPRDEG-- 475
Cdd:COG3840 23 AAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILW-NGQDLTALPpaerpvsmlfQENNlFPHLTVAQNIGLGLRPGlk 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 476 --DFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPAskLR 549
Cdd:COG3840 102 ltAEQRAQVEQALERVGLAGLLDRLPGQ----------LSGGQRQRVALARCLVRKRPILLLDEPFSALDPA--LR 165
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
409-547 |
6.17e-12 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 64.97 E-value: 6.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY-----PQGA---SSLYVPQEA--KFPSVSLKQLVALPRDEGDFN 478
Cdd:cd03226 24 YAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLngkpiKAKErrkSIGYVMQDVdyQLFTDSVREELLLGLKELDAG 103
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 479 DLAVAAVLHEAGLGEFIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:cd03226 104 NEQAETVLKDLDLYALKER--------HPLS--LSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNM 162
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
383-555 |
6.76e-12 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 65.23 E-value: 6.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQE------ 456
Cdd:cd03259 1 LELKGLSKTYG---SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILI-DGRDVTGVPPErrnigm 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 457 -----AKFPSVSLKQLVALPRDEGDFNDLAVAAVLHEA----GLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILL 527
Cdd:cd03259 77 vfqdyALFPHLTVAENIAFGLKLRGVPKAEIRARVRELlelvGLEGLLNRYPHE----------LSGGQQQRVALARALA 146
|
170 180
....*....|....*....|....*...
gi 974659840 528 HKPSIIFLDEATGALDPASKLRFHTALK 555
Cdd:cd03259 147 REPSLLLLDEPLSALDAKLREELREELK 174
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
421-543 |
7.72e-12 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 67.78 E-value: 7.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 421 GSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKF-PSVSLKQLVAlprdEGDFNDLAVAAVLHEAG--------- 490
Cdd:COG0488 34 GAGKSTLLKILAGELEPDSGEVSIPKGLRIGYLPQEPPLdDDLTVLDTVL----DGDAELRALEAELEELEaklaepded 109
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 974659840 491 ---LGEFIERMKDADA----------------GNSPWDM---VLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:COG0488 110 lerLAELQEEFEALGGweaearaeeilsglgfPEEDLDRpvsELSGGWRRRVALARALLSEPDLLLLDEPTNHLD 184
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
399-599 |
8.24e-12 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 65.33 E-value: 8.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 399 PFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL----------YVPQEAKFPSVSLKQL 467
Cdd:cd03253 15 PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSIlIDGQDIREVtldslrraigVVPQDTVLFNDTIGYN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 468 VALPRDegDFNDLAVAAVLHEAGLGEFIERMKDAdagnspWDMV-------LSGGQKQKVMLARILLHKPSIIFLDEATG 540
Cdd:cd03253 95 IRYGRP--DATDEEVIEAAKAAQIHDKIMRFPDG------YDTIvgerglkLSGGEKQRVAIARAILKNPPILLLDEATS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 541 ALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLESGESIFshVLDiaNGYVSLIPAH 599
Cdd:cd03253 167 ALDTHTEREIQAALRDVSKGRTTIVIAH--RLSTIVNADKII--VLK--DGRIVERGTH 219
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
418-568 |
8.82e-12 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 64.18 E-value: 8.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQE----AKFPsVSLKQLVALPR--DEGDFNDL------AVAAV 485
Cdd:NF040873 25 GPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRsevpDSLP-LTVRDLVAMGRwaRRGLWRRLtrddraAVDDA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 486 LHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPD-AIVV 564
Cdd:NF040873 104 LERVGLADLAGRQLGE----------LSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAEEHARgATVV 173
|
....
gi 974659840 565 SIMH 568
Cdd:NF040873 174 VVTH 177
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
379-568 |
9.09e-12 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 67.85 E-value: 9.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 379 PRFGLSVRNLTLMqGPASETPFLRSgvINMR--AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASS 450
Cdd:COG4618 327 PKGRLSVENLTVV-PPGSKRPILRG--VSFSlePGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVrldgadLSQWDREE 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 451 L-----YVPQEAKFPSVSLKQLVAlpR-DEGDFNDLAVAAVLheAGLGEFIERMKD------ADAGnspwdMVLSGGQKQ 518
Cdd:COG4618 404 LgrhigYLPQDVELFDGTIAENIA--RfGDADPEKVVAAAKL--AGVHEMILRLPDgydtriGEGG-----ARLSGGQRQ 474
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 974659840 519 KVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKT-RCPDAIVVSIMH 568
Cdd:COG4618 475 RIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRAlKARGATVVVITH 525
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
400-556 |
9.45e-12 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 65.05 E-value: 9.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 400 FLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---------PQGASSLYVPQE-AKFPSVSLKQLVA 469
Cdd:cd03299 14 KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLngkditnlpPEKRDISYVPQNyALFPHMTVYKNIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 -------LPRDEGDFNDLAVAAVLHeaglgefIERMKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:cd03299 94 yglkkrkVDKKEIERKVLEIAEMLG-------IDHLLNRKPET------LSGGEQQRVAIARALVVNPKILLLDEPFSAL 160
|
170
....*....|....
gi 974659840 543 DPASKLRFHTALKT 556
Cdd:cd03299 161 DVRTKEKLREELKK 174
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
383-545 |
1.07e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 65.81 E-value: 1.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLmQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpqGASSLyvpQEAKFPSV 462
Cdd:PRK13635 6 IRVEHISF-RYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITV--GGMVL---SEETVWDV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLK----------QLV-ALPRDEgdfndlaVAAVLHEAGL--GEFIERMKDAdagnspWDMV------------LSGGQK 517
Cdd:PRK13635 80 RRQvgmvfqnpdnQFVgATVQDD-------VAFGLENIGVprEEMVERVDQA------LRQVgmedflnrephrLSGGQK 146
|
170 180
....*....|....*....|....*...
gi 974659840 518 QKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:PRK13635 147 QRVAIAGVLALQPDIIILDEATSMLDPR 174
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
379-568 |
1.41e-11 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 63.97 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 379 PRFG-LSVRNLTLMQGPASEtPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL----- 451
Cdd:cd03369 2 PEHGeIEVENLSVRYAPDLP-PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIeIDGIDISTIpledl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 -----YVPQEAKFPSVSLKQLVAlPRDEGDFNDLAVAAVLHEAGLGefiermkdadagnspwdmvLSGGQKQKVMLARIL 526
Cdd:cd03369 81 rssltIIPQDPTLFSGTIRSNLD-PFDEYSDEEIYGALRVSEGGLN-------------------LSQGQRQLLCLARAL 140
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 974659840 527 LHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMH 568
Cdd:cd03369 141 LKRPRVLVLDEATASIDYATDALIQKTIREEFTNSTILTIAH 182
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
382-575 |
1.46e-11 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 64.04 E-value: 1.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 382 GLSVRNLTLMQGpasETPFLRSgvINMR--AGDWIYMRGESGSGKTSFIKALNGLWPYG---TGNIIYpQGASSLYVPQE 456
Cdd:COG4136 1 MLSLENLTITLG---GRPLLAP--LSLTvaPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLL-NGRRLTALPAE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 457 AK-----------FP--SVSLKQLVALPRDEGDFN-DLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVML 522
Cdd:COG4136 75 QRrigilfqddllFPhlSVGENLAFALPPTIGRAQrRARVEQALEEAGLAGFADRDPAT----------LSGGQRARVAL 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 974659840 523 ARILLHKPSIIFLDEATGALDPASKLRFHtalktrcpdAIVVSIMHEEKLPTL 575
Cdd:COG4136 145 LRALLAEPRALLLDEPFSKLDAALRAQFR---------EFVFEQIRQRGIPAL 188
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
409-593 |
1.54e-11 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 64.29 E-value: 1.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGA--SSL--------------YVPQEAK-FPSVSLKQLVALP 471
Cdd:COG1136 32 EAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLI-DGQdiSSLserelarlrrrhigFVFQFFNlLPELTALENVALP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 472 -------RDEgdfNDLAVAAVLHEAGLGEFIERMkdadagnsPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG1136 111 lllagvsRKE---RRERARELLERVGLGDRLDHR--------PSQ--LSGGQQQRVAIARALVNRPKLILADEPTGNLDS 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 974659840 545 ASKLRFHTALKTRCPDA----IVVSimHEEKLptlesgESIFSHVLDIANGYV 593
Cdd:COG1136 178 KTGEEVLELLRELNRELgttiVMVT--HDPEL------AARADRVIRLRDGRI 222
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
418-546 |
1.68e-11 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 64.80 E-value: 1.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALN---GLWP--YGTGNIIYpqGASSLYVPqeaKFPSVSLKQLVAL----PRD------EGDFNDLAV 482
Cdd:PRK14239 38 GPSGSGKSTLLRSINrmnDLNPevTITGSIVY--NGHNIYSP---RTDTVDLRKEIGMvfqqPNPfpmsiyENVVYGLRL 112
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 483 AAVLHEAGLGEFIERmkdADAGNSPWDMV----------LSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:PRK14239 113 KGIKDKQVLDEAVEK---SLKGASIWDEVkdrlhdsalgLSGGQQQRVCIARVLATSPKIILLDEPTSALDPIS 183
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
400-593 |
1.69e-11 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 64.05 E-value: 1.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 400 FLRSGVINMR------AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY-----------PQGASSLYvpQEAK-FPS 461
Cdd:cd03298 7 RFSYGEQPMHfdltfaQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLIngvdvtaappaDRPVSMLF--QENNlFAH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 VSLKQLVALPRDEG----DFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDE 537
Cdd:cd03298 85 LTVEQNVGLGLSPGlkltAEDRQAIEVALARVGLAGLEKRLPGE----------LSGGERQRVALARVLVRDKPVLLLDE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 538 ATGALDPASKLRFHTALKTRCPDAIVVSIM--HeeklpTLESGESIFSHVLDIANGYV 593
Cdd:cd03298 155 PFAALDPALRAEMLDLVLDLHAETKMTVLMvtH-----QPEDAKRLAQRVVFLDNGRI 207
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
383-553 |
1.78e-11 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 63.64 E-value: 1.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASETPFLRSGVINMRA--GDWIYMRGESGSGKTSFIKALNG-LWPYGtGNIIYPQGASslYVPQEAKF 459
Cdd:cd03250 1 ISVEDASFTWDSGEQETSFTLKDINLEVpkGELVAIVGPVGSGKSSLLSALLGeLEKLS-GSVSVPGSIA--YVSQEPWI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 460 PSVSLKQ--LVALPRDEGDFNDlavaaVLHEAGLGEFIERMKDADA------GNSpwdmvLSGGQKQKVMLARILLHKPS 531
Cdd:cd03250 78 QNGTIREniLFGKPFDEERYEK-----VIKACALEPDLEILPDGDLteigekGIN-----LSGGQKQRISLARAVYSDAD 147
|
170 180
....*....|....*....|..
gi 974659840 532 IIFLDEATGALDPasklrfHTA 553
Cdd:cd03250 148 IYLLDDPLSAVDA------HVG 163
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
409-555 |
2.57e-11 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 66.41 E-value: 2.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYgTGNI-IYPQGASSL----------YVPQEAKFPSVSLKQLVALPRdeGDF 477
Cdd:PRK11174 374 PAGQRIALVGPSGAGKTSLLNALLGFLPY-QGSLkINGIELRELdpeswrkhlsWVGQNPQLPHGTLRDNVLLGN--PDA 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 NDLAVAAVLHEAGLGEFIERM--------KDADAGnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLR 549
Cdd:PRK11174 451 SDEQLQQALENAWVSEFLPLLpqgldtpiGDQAAG-------LSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQL 523
|
....*.
gi 974659840 550 FHTALK 555
Cdd:PRK11174 524 VMQALN 529
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
406-543 |
2.80e-11 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 66.52 E-value: 2.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYP-QGASSL----------YVPQEAKFPSVSLKQLVA----L 470
Cdd:TIGR03797 474 LQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDgQDLAGLdvqavrrqlgVVLQNGRLMSGSIFENIAggapL 553
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 471 PRDEgdfndlaVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:TIGR03797 554 TLDE-------AWEAARMAGLAEDIRAMPMgmhtviSEGGGT-----LSGGQRQRLLIARALVRKPRILLFDEATSALD 620
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
418-568 |
2.84e-11 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 64.02 E-value: 2.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNG-LWPYgTGNIIY----------PQGASSLYV-PQEAK--FP-SVSlkQLVAL-----PRDEGDF 477
Cdd:PRK13548 35 GPNGAGKSTLLRALSGeLSPD-SGEVRLngrpladwspAELARRRAVlPQHSSlsFPfTVE--EVVAMgraphGLSRAED 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 NDLaVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILL------HKPSIIFLDEATGALDPASKLRFH 551
Cdd:PRK13548 112 DAL-VAAALAQVDLAHLAGRDYPQ----------LSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVL 180
|
170
....*....|....*....
gi 974659840 552 TALKTRCPD--AIVVSIMH 568
Cdd:PRK13548 181 RLARQLAHErgLAVIVVLH 199
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
406-554 |
3.04e-11 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 63.80 E-value: 3.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVP----------QE-AKFPSVSLKQLVALP--- 471
Cdd:cd03300 21 LDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILL-DGKDITNLPphkrpvntvfQNyALFPHLTVFENIAFGlrl 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 472 -RDEGDFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDpaSKLRF 550
Cdd:cd03300 100 kKLPKAEIKERVAEALDLVQLEGYANRKPSQ----------LSGGQQQRVAIARALVNEPKVLLLDEPLGALD--LKLRK 167
|
....
gi 974659840 551 HTAL 554
Cdd:cd03300 168 DMQL 171
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
406-544 |
3.19e-11 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 63.32 E-value: 3.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYVPQEAK--------FPSVSLKQLVALP 471
Cdd:cd03262 21 LTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIiidglkLTDDKKNINELRQKVGmvfqqfnlFPHLTVLENITLA 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 472 ------RDEGDFNDLAVAAvLHEAGLGEFiermkdADAgnspWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:cd03262 101 pikvkgMSKAEAEERALEL-LEKVGLADK------ADA----YPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDP 168
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
383-549 |
3.32e-11 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 63.96 E-value: 3.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLM-QGPASETPFLRSgvINM--RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYP------QGASSLYV 453
Cdd:COG1116 8 LELRGVSKRfPTGGGGVTALDD--VSLtvAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDgkpvtgPGPDRGVV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 454 PQEAK-FPSVSLKQLVALP----------RDEgdfndlAVAAVLHEAGLGEFIERMkdadagnsPWDmvLSGGQKQKVML 522
Cdd:COG1116 86 FQEPAlLPWLTVLDNVALGlelrgvpkaeRRE------RARELLELVGLAGFEDAY--------PHQ--LSGGMRQRVAI 149
|
170 180
....*....|....*....|....*..
gi 974659840 523 ARILLHKPSIIFLDEATGALDPASKLR 549
Cdd:COG1116 150 ARALANDPEVLLMDEPFGALDALTRER 176
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
383-593 |
7.43e-11 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 65.04 E-value: 7.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQgPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLyvpqE 456
Cdd:PRK11176 342 IEFRNVTFTY-PGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEIlldghdLRDYTLASL----R 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 457 AKFPSVSlkQLVALprdegdFND-----LAVAA--------VLHEAGLG---EFIERMKDAdagnspWDMV-------LS 513
Cdd:PRK11176 417 NQVALVS--QNVHL------FNDtiannIAYARteqysreqIEEAARMAyamDFINKMDNG------LDTVigengvlLS 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 514 GGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLESGESIfshvLDIANGYV 593
Cdd:PRK11176 483 GGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAH--RLSTIEKADEI----LVVEDGEI 556
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
383-558 |
7.65e-11 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 61.61 E-value: 7.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGAsslyVPQEAKFPSV 462
Cdd:TIGR01189 1 LAARNLACSRG---ERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTP----LAEQRDEPHE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQLVALPrdeGDFNDLAVAAVLHeaglgeFIERMKDaDAGNSPWDMV---------------LSGGQKQKVMLARILL 527
Cdd:TIGR01189 74 NILYLGHLP---GLKPELSALENLH------FWAAIHG-GAQRTIEDALaavgltgfedlpaaqLSAGQQRRLALARLWL 143
|
170 180 190
....*....|....*....|....*....|.
gi 974659840 528 HKPSIIFLDEATGALDPASKLRFHTALKTRC 558
Cdd:TIGR01189 144 SRRPLWILDEPTTALDKAGVALLAGLLRAHL 174
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
394-591 |
8.13e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 63.28 E-value: 8.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 394 PASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNG-LWPYGTGN-IIYPQG----ASSLYVPQEA---------- 457
Cdd:PRK13640 16 PDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlLLPDDNPNsKITVDGitltAKTVWDIREKvgivfqnpdn 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 458 KFPSVSLKQLVA-------LPRDEgdfNDLAVAAVLHEAGLGEFIermkDADAGNspwdmvLSGGQKQKVMLARILLHKP 530
Cdd:PRK13640 96 QFVGATVGDDVAfglenraVPRPE---MIKIVRDVLADVGMLDYI----DSEPAN------LSGGQKQRVAIAGILAVEP 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 974659840 531 SIIFLDEATGALDPASKLRFhtaLKtrcpdaIVVSIMHEEKLptlesgeSIFS--HVLDIANG 591
Cdd:PRK13640 163 KIIILDESTSMLDPAGKEQI---LK------LIRKLKKKNNL-------TVISitHDIDEANM 209
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
410-558 |
8.96e-11 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 61.74 E-value: 8.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 410 AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGA----------SSLYVPQEAKFPSV--SLKQLVALPRDEGDf 477
Cdd:cd03231 25 AGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPldfqrdsiarGLLYLGHAPGIKTTlsVLENLRFWHADHSD- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 ndLAVAAVLHEAGLGEFiermKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTR 557
Cdd:cd03231 104 --EQVEEALARVGLNGF----EDRPVAQ------LSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGH 171
|
.
gi 974659840 558 C 558
Cdd:cd03231 172 C 172
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
383-547 |
1.25e-10 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 62.47 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPasETPFLRSGV--INMR--AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpqgaSSLYVPQEAK 458
Cdd:TIGR04521 1 IKLKNVSYIYQP--GTPFEKKALddVSLTieDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTI----DGRDITAKKK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 459 FPSVSLKQLVAL----PRD----EGDFNDLA----------------VAAVLHEAGLGE-FIERmkdadagnSPWDmvLS 513
Cdd:TIGR04521 75 KKLKDLRKKVGLvfqfPEHqlfeETVYKDIAfgpknlglseeeaeerVKEALELVGLDEeYLER--------SPFE--LS 144
|
170 180 190
....*....|....*....|....*....|....
gi 974659840 514 GGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:TIGR04521 145 GGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGR 178
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
418-568 |
1.33e-10 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 62.06 E-value: 1.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY---PQGASSLY--------VPQEAK--FP-SVslKQLVAL---PRDEGDFNDL 480
Cdd:COG4559 34 GPNGAGKSTLLKLLTGELTPSSGEVRLngrPLAAWSPWelarrravLPQHSSlaFPfTV--EEVVALgraPHGSSAAQDR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 481 AVA-AVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILL-------HKPSIIFLDEATGALDPASKLRFHT 552
Cdd:COG4559 112 QIVrEALALVGLAHLAGRSYQT----------LSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLR 181
|
170
....*....|....*...
gi 974659840 553 ALK--TRCPDAiVVSIMH 568
Cdd:COG4559 182 LARqlARRGGG-VVAVLH 198
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
410-543 |
1.72e-10 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 62.00 E-value: 1.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 410 AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIypQGASSL--------YVPQEAKF-PSVSLKQLVALPRdEGDFNDL 480
Cdd:PRK11247 37 AGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL--AGTAPLaearedtrLMFQDARLlPWKKVIDNVGLGL-KGQWRDA 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 974659840 481 AVAAvLHEAGLGEfieRMKDadagnspWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11247 114 ALQA-LAAVGLAD---RANE-------WPAALSGGQKQRVALARALIHRPGLLLLDEPLGALD 165
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
453-568 |
3.67e-10 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 63.12 E-value: 3.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 453 VPQEAKFPSVSLKQLVALPRDEGDFNDLAVAAVLheAGLGEFIERMKDA-DAGNSPWDMVLSGGQKQKVMLARILLHKPS 531
Cdd:PTZ00265 1301 VSQEPMLFNMSIYENIKFGKEDATREDVKRACKF--AAIDEFIESLPNKyDTNVGPYGKSLSGGQKQRIAIARALLREPK 1378
|
90 100 110
....*....|....*....|....*....|....*....
gi 974659840 532 IIFLDEATGALDPAS-KLRFHTALKTR-CPDAIVVSIMH 568
Cdd:PTZ00265 1379 ILLLDEATSSLDSNSeKLIEKTIVDIKdKADKTIITIAH 1417
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
418-547 |
4.35e-10 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 59.83 E-value: 4.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPqGASSL-----------YVPQE-AKFPSVSLKQLV-------ALPRDEGDFN 478
Cdd:cd03263 35 GHNGAGKTTTLKMLTGELRPTSGTAYIN-GYSIRtdrkaarqslgYCPQFdALFDELTVREHLrfyarlkGLPKSEIKEE 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 479 dlaVAAVLHEAGLGEFiermKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:cd03263 114 ---VELLLRVLGLTDK----ANKRART------LSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASR 169
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
383-543 |
5.08e-10 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 60.65 E-value: 5.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLM-QGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYVPQ 455
Cdd:COG4525 4 LTVRHVSVRyPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEItldgvpVTGPGADRGVVFQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 456 -EAKFPSVSLKQLVAL-------PRDEgdfnDLAVA-AVLHEAGLGEFIERMkdadagnsPWDmvLSGGQKQKVMLARIL 526
Cdd:COG4525 84 kDALLPWLNVLDNVAFglrlrgvPKAE----RRARAeELLALVGLADFARRR--------IWQ--LSGGMRQRVGIARAL 149
|
170
....*....|....*..
gi 974659840 527 LHKPSIIFLDEATGALD 543
Cdd:COG4525 150 AADPRFLLMDEPFGALD 166
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
385-544 |
5.16e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 60.83 E-value: 5.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 385 VRNLT--LMQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYV--- 453
Cdd:PRK13637 5 IENLThiYMEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIiidgvdITDKKVKLSDIrkk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 454 -------PQEAKFPSVSLKQLVALPRD----EGDFNDlAVAAVLHEAGLGefIERMKDadagNSPWDmvLSGGQKQKVML 522
Cdd:PRK13637 85 vglvfqyPEYQLFEETIEKDIAFGPINlglsEEEIEN-RVKRAMNIVGLD--YEDYKD----KSPFE--LSGGQKRRVAI 155
|
170 180
....*....|....*....|..
gi 974659840 523 ARILLHKPSIIFLDEATGALDP 544
Cdd:PRK13637 156 AGVVAMEPKILILDEPTAGLDP 177
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
397-555 |
5.19e-10 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 60.11 E-value: 5.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 397 ETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSL-------YVPQEAK--------FPs 461
Cdd:PRK09493 13 PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIV-DGLKVNdpkvderLIRQEAGmvfqqfylFP- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 vslkQLVAL------PR-----DEGDFNDLAvAAVLHEAGLGEfiermkdaDAGNSPWDmvLSGGQKQKVMLARILLHKP 530
Cdd:PRK09493 91 ----HLTALenvmfgPLrvrgaSKEEAEKQA-RELLAKVGLAE--------RAHHYPSE--LSGGQQQRVAIARALAVKP 155
|
170 180
....*....|....*....|....*
gi 974659840 531 SIIFLDEATGALDPasKLRfHTALK 555
Cdd:PRK09493 156 KLMLFDEPTSALDP--ELR-HEVLK 177
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
418-551 |
5.75e-10 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 59.82 E-value: 5.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYV---------PQEAKFPSVSLKQLVALP------RDEGD 476
Cdd:cd03261 33 GPSGSGKSTLLRLIVGLLRPDSGEVlidgedISGLSEAELYRlrrrmgmlfQSGALFDSLTVFENVAFPlrehtrLSEEE 112
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 974659840 477 FNDLaVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:cd03261 113 IREI-VLEKLEAVGLRGAEDLYPAE----------LSGGMKKRVALARALALDPELLLYDEPTAGLDPIASGVID 176
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
396-569 |
5.92e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 60.54 E-value: 5.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 396 SETPFLRSGV-INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY------PQGASSL-----YVPQ--EAKFPS 461
Cdd:PRK13648 19 SDASFTLKDVsFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYnnqaitDDNFEKLrkhigIVFQnpDNQFVG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 VSLKQLVALprdegdfnDLAVAAVLHEAGLGEFIERMKDAD----AGNSPwdMVLSGGQKQKVMLARILLHKPSIIFLDE 537
Cdd:PRK13648 99 SIVKYDVAF--------GLENHAVPYDEMHRRVSEALKQVDmlerADYEP--NALSGGQKQRVAIAGVLALNPSVIILDE 168
|
170 180 190
....*....|....*....|....*....|....*
gi 974659840 538 ATGALDPASK---LRFHTALKTRcPDAIVVSIMHE 569
Cdd:PRK13648 169 ATSMLDPDARqnlLDLVRKVKSE-HNITIISITHD 202
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
385-569 |
6.34e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 60.52 E-value: 6.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 385 VRNLTLMQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQgasslyvpQEAKFPSV-S 463
Cdd:PRK13650 7 VKNLTFKYKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDG--------DLLTEENVwD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 464 LKQLVALPRDEGDfNDLAVAAVLHEAGLG---------EFIERMKDADA--GNSPWDMV----LSGGQKQKVMLARILLH 528
Cdd:PRK13650 79 IRHKIGMVFQNPD-NQFVGATVEDDVAFGlenkgipheEMKERVNEALElvGMQDFKEReparLSGGQKQRVAIAGAVAM 157
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 974659840 529 KPSIIFLDEATGALDPASKLRF-HTALKTRCP-DAIVVSIMHE 569
Cdd:PRK13650 158 RPKIIILDEATSMLDPEGRLELiKTIKGIRDDyQMTVISITHD 200
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
406-549 |
7.40e-10 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 59.62 E-value: 7.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL-----YVPQEAK-FPSVSLKQLVAL-PR 472
Cdd:cd03295 22 LEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIfidgedIREQDPVELrrkigYVIQQIGlFPHMTVEENIALvPK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 473 DEG---DFNDLAVAAVLHEAGL--GEFIERMkdadagnsPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:cd03295 102 LLKwpkEKIRERADELLALVGLdpAEFADRY--------PHE--LSGGQQQRVGVARALAADPPLLLMDEPFGALDPITR 171
|
..
gi 974659840 548 LR 549
Cdd:cd03295 172 DQ 173
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
418-546 |
7.49e-10 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 59.69 E-value: 7.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL-------------YVPQEakFP-----SV-------------SLK 465
Cdd:COG3638 36 GPSGAGKSTLLRCLNGLVEPTSGEIlVDGQDVTALrgralrrlrrrigMIFQQ--FNlvprlSVltnvlagrlgrtsTWR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 466 QLVALPRDEgdfnDLAVA-AVLHEAGLGEFIERMkdADAgnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG3638 114 SLLGLFPPE----DRERAlEALERVGLADKAYQR--ADQ--------LSGGQQQRVAIARALVQEPKLILADEPVASLDP 179
|
..
gi 974659840 545 AS 546
Cdd:COG3638 180 KT 181
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
418-548 |
9.99e-10 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 58.85 E-value: 9.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGL--------------WPYGTGNIIYP--QGASSLYVPQEAKFPSVSLKQLVA--LPRDEGDFND 479
Cdd:cd03297 30 GASGAGKSTLLRCIAGLekpdggtivlngtvLFDSRKKINLPpqQRKIGLVFQQYALFPHLNVRENLAfgLKRKRNREDR 109
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 480 LAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKL 548
Cdd:cd03297 110 ISVDELLDLLGLDHLLNRYPAQ----------LSGGEKQRVALARALAAQPELLLLDEPFSALDRALRL 168
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
370-584 |
1.10e-09 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 59.60 E-value: 1.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 370 NRFAFTHQHPRFGlsvrnltlmqgpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGAS 449
Cdd:PRK10619 4 NKLNVIDLHKRYG--------------EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 450 SLYVPQEAKFPSVSLKQLVALpRDE-----GDFNDLAVAAVLH---EA-----GLGE---------FIERMKDADAGNSP 507
Cdd:PRK10619 70 NLVRDKDGQLKVADKNQLRLL-RTRltmvfQHFNLWSHMTVLEnvmEApiqvlGLSKqeareravkYLAKVGIDERAQGK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 508 WDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDP---ASKLRFHTALKTRCPDAIVVSimHEEKLPTLESGESIFSH 584
Cdd:PRK10619 149 YPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPelvGEVLRIMQQLAEEGKTMVVVT--HEMGFARHVSSHVIFLH 226
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
418-546 |
1.27e-09 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 58.75 E-value: 1.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQGasslyvpQEAKfpSVSLKQLVALPRDEG----DFNDLA-------VAAVL 486
Cdd:cd03258 38 GRSGAGKSTLIRCINGLERPTSGSVLV-DG-------TDLT--LLSGKELRKARRRIGmifqHFNLLSsrtvfenVALPL 107
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 487 HEAGLG--EFIERMKD-------AD-AGNSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:cd03258 108 EIAGVPkaEIEERVLEllelvglEDkADAYPAQ--LSGGQKQRVGIARALANNPKVLLCDEATSALDPET 175
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
418-547 |
1.79e-09 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 59.73 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNI-----IYPQGASSL----------YVPQEAK-FPSVSLKQ-------LVALPRDE 474
Cdd:COG4148 32 GPSGSGKTTLLRAIAGLERPDSGRIrlggeVLQDSARGIflpphrrrigYVFQEARlFPHLSVRGnllygrkRAPRAERR 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 974659840 475 GDFNDlaVAAVLheaGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:COG4148 112 ISFDE--VVELL---GIGHLLDRRPAT----------LSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARK 169
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
418-582 |
2.17e-09 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 60.51 E-value: 2.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLY-----------VPQEAKFPSVSLKQLVALPRDegDFNDLAVAAVL 486
Cdd:TIGR00958 514 GPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYdhhylhrqvalVGQEPVLFSGSVRENIAYGLT--DTPDEEIMAAA 591
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 487 HEAGLGEFIERM-KDADAGNSPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRcpDAIVVS 565
Cdd:TIGR00958 592 KAANAHDFIMEFpNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQLLQESRSRA--SRTVLL 669
|
170
....*....|....*..
gi 974659840 566 IMHeeKLPTLESGESIF 582
Cdd:TIGR00958 670 IAH--RLSTVERADQIL 684
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
383-543 |
2.80e-09 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 59.47 E-value: 2.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpasETPFLrSGV-INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI--------------IYPQG 447
Cdd:PRK09536 4 IDVSDLSVEFG---DTTVL-DGVdLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVlvagddvealsaraASRRV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 448 ASslyVPQEAKFP-SVSLKQLVALPR--------DEGDFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQ 518
Cdd:PRK09536 80 AS---VPQDTSLSfEFDVRQVVEMGRtphrsrfdTWTETDRAAVERAMERTGVAQFADRPVTS----------LSGGERQ 146
|
170 180
....*....|....*....|....*
gi 974659840 519 KVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK09536 147 RVLLARALAQATPVLLLDEPTASLD 171
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
383-547 |
2.88e-09 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 58.21 E-value: 2.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLmQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIypqgASSLYVPQEAKFPSV 462
Cdd:TIGR04520 1 IEVENVSF-SYPESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVT----VDGLDTLDEENLWEI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLK----------QLVA---------------LPRDEgdfNDLAVAAVLHEAGLGEFIERmkdadagnSPWDmvLSGGQK 517
Cdd:TIGR04520 76 RKKvgmvfqnpdnQFVGatveddvafglenlgVPREE---MRKRVDEALKLVGMEDFRDR--------EPHL--LSGGQK 142
|
170 180 190
....*....|....*....|....*....|
gi 974659840 518 QKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:TIGR04520 143 QRVAIAGVLAMRPDIIILDEATSMLDPKGR 172
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
418-593 |
3.01e-09 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 57.79 E-value: 3.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNG-LWPyGTGNIIY----PQGASSL--------YVPQE--AKFP-SVSLKQLVA--------LPRD 473
Cdd:COG1119 36 GPNGAGKSTLLSLITGdLPP-TYGNDVRlfgeRRGGEDVwelrkrigLVSPAlqLRFPrDETVLDVVLsgffdsigLYRE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 474 EGDFNDLAVAAVLHEAGLGEFIERmkdadagnsPWDmVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTA 553
Cdd:COG1119 115 PTDEQRERARELLELLGLAHLADR---------PFG-TLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLAL 184
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 974659840 554 LKTRCPDAIVVSIM---HEEKLPtlesgeSIFSHVLDIANGYV 593
Cdd:COG1119 185 LDKLAAEGAPTLVLvthHVEEIP------PGITHVLLLKDGRV 221
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
410-593 |
3.57e-09 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 57.72 E-value: 3.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 410 AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKfpsvslkQLVALPRDEG----DFN---DLAV 482
Cdd:PRK11124 27 QGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSKTPSDK-------AIRELRRNVGmvfqQYNlwpHLTV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 483 AAVLHEA-----GLG---------EFIERMKDADAGNSpWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKl 548
Cdd:PRK11124 100 QQNLIEApcrvlGLSkdqalaraeKLLERLRLKPYADR-FPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEIT- 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 974659840 549 rfhtalktrcpdAIVVSIMHE-------EKLPTLESG--ESIFSHVLDIANGYV 593
Cdd:PRK11124 178 ------------AQIVSIIRElaetgitQVIVTHEVEvaRKTASRVVYMENGHI 219
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
383-544 |
3.87e-09 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 56.17 E-value: 3.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLmQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPSV 462
Cdd:cd03247 1 LSINNVSF-SYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSLISV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 sLKQLVALprdegdFNDlavaavlheaGLGEFIERMkdadagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:cd03247 80 -LNQRPYL------FDT----------TLRNNLGRR-------------FSGGERQRLALARILLQDAPIVLLDEPTVGL 129
|
..
gi 974659840 543 DP 544
Cdd:cd03247 130 DP 131
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
395-548 |
3.96e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 58.30 E-value: 3.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 395 ASETPFLRSGVIN----MRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASS------------LY 452
Cdd:PRK13641 13 SPGTPMEKKGLDNisfeLEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTItiagyhITPETGNKnlkklrkkvslvFQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 453 VPQEAKFPSVSLKQLVALPRDEGDFNDLAVAAVLheaglgEFIER--MKDADAGNSPWDmvLSGGQKQKVMLARILLHKP 530
Cdd:PRK13641 93 FPEAQLFENTVLKDVEFGPKNFGFSEDEAKEKAL------KWLKKvgLSEDLISKSPFE--LSGGQMRRVAIAGVMAYEP 164
|
170
....*....|....*...
gi 974659840 531 SIIFLDEATGALDPASKL 548
Cdd:PRK13641 165 EILCLDEPAAGLDPEGRK 182
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
418-582 |
4.93e-09 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 56.41 E-value: 4.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYG--TGNIIY---PQGASSL-----YVPQEakfpsvslkqLVALPrdegdfnDLAVAAVLH 487
Cdd:cd03213 42 GPSGAGKSTLLNALAGRRTGLgvSGEVLIngrPLDKRSFrkiigYVPQD----------DILHP-------TLTVRETLM 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 488 eaglgeFIERMKdadagnspwdmVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAI-VVSI 566
Cdd:cd03213 105 ------FAAKLR-----------GLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADTGRtIICS 167
|
170 180
....*....|....*....|....*
gi 974659840 567 MHE---------EKLPTLESGESIF 582
Cdd:cd03213 168 IHQpsseifelfDKLLLLSQGRVIY 192
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
406-567 |
6.61e-09 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 56.71 E-value: 6.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYVPQE-AKFPSVSLKQLVALprdegdfn 478
Cdd:TIGR01184 6 LTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVilegkqITEPGPDRMVVFQNySLLPWLTVRENIAL-------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 479 dlAVAAVLHEAGLGE-------FIERMKDADAGNSPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:TIGR01184 78 --AVDRVLPDLSKSErraiveeHIALVGLTEAADKRPGQ-LSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQ 154
|
170
....*....|....*.
gi 974659840 552 TALKTRCPDAIVVSIM 567
Cdd:TIGR01184 155 EELMQIWEEHRVTVLM 170
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
406-555 |
6.82e-09 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 56.26 E-value: 6.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLY----VPQEAKFPSVSLKQLVALPrDEGDFNDLA 481
Cdd:cd03292 22 ISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLrgraIPYLRRKIGVVFQDFRLLP-DRNVYENVA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 482 VAAVLHEAGLGEFIERMKDA-------DAGNSpWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTAL 554
Cdd:cd03292 101 FALEVTGVPPREIRKRVPAAlelvglsHKHRA-LPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLL 179
|
.
gi 974659840 555 K 555
Cdd:cd03292 180 K 180
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
383-593 |
7.93e-09 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 56.12 E-value: 7.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGP-ASETPFLR--SGVINmrAGDWIYMRGESGSGKTSFIKALNG-LWPYG--TGNIIYP----------Q 446
Cdd:cd03233 4 LSWRNISFTTGKgRSKIPILKdfSGVVK--PGEMVLVLGRPGSGCSTLLKALANrTEGNVsvEGDIHYNgipykefaekY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 447 GASSLYVPQE-AKFPSVSLKQLValprdegdfndlavaavlheaglgEFIERMKdadaGNspwDMV--LSGGQKQKVMLA 523
Cdd:cd03233 82 PGEIIYVSEEdVHFPTLTVRETL------------------------DFALRCK----GN---EFVrgISGGERKRVSIA 130
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 524 RILLHKPSIIFLDEATGALDPASKLRFHTALKTrcpdaivvsIMHEEKLPTLES----GESI---FSHVLDIANGYV 593
Cdd:cd03233 131 EALVSRASVLCWDNSTRGLDSSTALEILKCIRT---------MADVLKTTTFVSlyqaSDEIydlFDKVLVLYEGRQ 198
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
418-565 |
8.62e-09 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 54.38 E-value: 8.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQeakfpsvslkqlvalprdegdfndlavaavlheaglgefier 497
Cdd:cd03221 33 GRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGYFEQ------------------------------------------ 70
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 498 mkdadagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVS 565
Cdd:cd03221 71 --------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEYPGTVILVS 124
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
418-544 |
9.05e-09 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 56.88 E-value: 9.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL--------------YVPQE-AKFPSVSLKQLVALP---RDEGDFN 478
Cdd:cd03294 57 GLSGSGKSTLLRCINRLIEPTSGKVlIDGQDIAAMsrkelrelrrkkisMVFQSfALLPHRTVLENVAFGlevQGVPRAE 136
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 479 DLAVAA-VLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:cd03294 137 REERAAeALELVGLEGWEHKYPDE----------LSGGMQQRVGLARALAVDPDILLMDEAFSALDP 193
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
418-549 |
9.35e-09 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 57.42 E-value: 9.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQG--ASSL--------YVPQE-AKFP--SV------SLKQLvALPRDEGDFn 478
Cdd:COG3842 38 GPSGCGKTTLLRMIAGFETPDSGRILL-DGrdVTGLppekrnvgMVFQDyALFPhlTVaenvafGLRMR-GVPKAEIRA- 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 479 dlAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPasKLR 549
Cdd:COG3842 115 --RVAELLELVGLEGLADRYPHQ----------LSGGQQQRVALARALAPEPRVLLLDEPLSALDA--KLR 171
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
418-545 |
9.68e-09 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 55.90 E-value: 9.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY---------PQGASSL---YVPQEAK-FPSVSLK---QLVALPRDEGDFNDlA 481
Cdd:cd03224 33 GRNGAGKTTLLKTIMGLLPPRSGSIRFdgrditglpPHERARAgigYVPEGRRiFPELTVEenlLLGAYARRRAKRKA-R 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 482 VAAVLheaglGEF--IERMKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:cd03224 112 LERVY-----ELFprLKERRKQLAGT------LSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPK 166
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
411-545 |
1.01e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 57.02 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 411 GDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpqgassLYVPQEAK-----FPSVSLKQLVALPRD------------ 473
Cdd:PRK13651 33 GEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEW------IFKDEKNKkktkeKEKVLEKLVIQKTRFkkikkikeirrr 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 474 -----------------EGD--FNDLAVAAVLHEA-----------GLGE-FIERmkdadagnSPWDmvLSGGQKQKVML 522
Cdd:PRK13651 107 vgvvfqfaeyqlfeqtiEKDiiFGPVSMGVSKEEAkkraakyielvGLDEsYLQR--------SPFE--LSGGQKRRVAL 176
|
170 180
....*....|....*....|...
gi 974659840 523 ARILLHKPSIIFLDEATGALDPA 545
Cdd:PRK13651 177 AGILAMEPDFLVFDEPTAGLDPQ 199
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
411-549 |
1.22e-08 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 57.15 E-value: 1.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 411 GDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVP-----------QEAKFPSVSLKQLVA-------LPR 472
Cdd:PRK11607 45 GEIFALLGASGCGKSTLLRMLAGFEQPTAGQIML-DGVDLSHVPpyqrpinmmfqSYALFPHMTVEQNIAfglkqdkLPK 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 473 DEgdFNDlAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDpaSKLR 549
Cdd:PRK11607 124 AE--IAS-RVNEMLGLVHMQEFAKRKPHQ----------LSGGQRQRVALARSLAKRPKLLLLDEPMGALD--KKLR 185
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
410-544 |
1.26e-08 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 56.17 E-value: 1.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 410 AGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQgasslyvpQEAKFPS-VSLKQLVALPRDEG----DFN---DLA 481
Cdd:COG4161 27 SGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAG--------HQFDFSQkPSEKAIRLLRQKVGmvfqQYNlwpHLT 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 482 VAAVLHEA-----GLG---------EFIERMKDADAGNSpWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG4161 99 VMENLIEApckvlGLSkeqarekamKLLARLRLTDKADR-FPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDP 174
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
383-581 |
1.41e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 56.25 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGnIIYPQG----ASSLYvpqeak 458
Cdd:PRK13642 5 LEVENLVFKYEKESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEG-KVKIDGelltAENVW------ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 459 fpsvSLKQLVALPRDEGDfNDLAVAAVLHEAGLG---------EFIERMKDADAGNSPWDMV------LSGGQKQKVMLA 523
Cdd:PRK13642 78 ----NLRRKIGMVFQNPD-NQFVGATVEDDVAFGmenqgipreEMIKRVDEALLAVNMLDFKtreparLSGGQKQRVAVA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 524 RILLHKPSIIFLDEATGALDPASK---LRFHTALKTRCpDAIVVSIMHE-------EKLPTLESGESI 581
Cdd:PRK13642 153 GIIALRPEIIILDESTSMLDPTGRqeiMRVIHEIKEKY-QLTVLSITHDldeaassDRILVMKAGEII 219
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
418-550 |
1.50e-08 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 55.76 E-value: 1.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY------------------------PQGA--SSLYVPQEAKFPsvsLKQLVALP 471
Cdd:COG1127 38 GGSGSGKSVLLKLIIGLLRPDSGEILVdgqditglsekelyelrrrigmlfQGGAlfDSLTVFENVAFP---LREHTDLS 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 472 RDEGDfnDLaVAAVLHEAGLGEFIERMkdadagnsPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRF 550
Cdd:COG1127 115 EAEIR--EL-VLEKLELVGLPGAADKM--------PSE--LSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVI 180
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
406-548 |
1.52e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 56.28 E-value: 1.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLW--PYGT---GNIIYPQGASS-------------LYVPQEAKFPSVSLKQL 467
Cdd:PRK13643 27 LEVKKGSYTALIGHTGSGKSTLLQHLNGLLqpTEGKvtvGDIVVSSTSKQkeikpvrkkvgvvFQFPESQLFEETVLKDV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 468 VALPRDEGDFNDLA---VAAVLHEAGLG-EFIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK13643 107 AFGPQNFGIPKEKAekiAAEKLEMVGLAdEFWEK--------SPFE--LSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD 176
|
....*
gi 974659840 544 PASKL 548
Cdd:PRK13643 177 PKARI 181
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
406-543 |
1.67e-08 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 56.63 E-value: 1.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL--------YVPQE-AKFPSVSLKQLVA-----L 470
Cdd:PRK10851 23 LDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIrFHGTDVSRLhardrkvgFVFQHyALFRHMTVFDNIAfgltvL 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 471 PRDE---GDFNDLAVAAVLHEAGLGEFIERmkdadagnspWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK10851 103 PRRErpnAAAIKAKVTQLLEMVQLAHLADR----------YPAQLSGGQKQRVALARALAVEPQILLLDEPFGALD 168
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
414-543 |
1.72e-08 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 55.56 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 414 IYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSLYVPQEAK---------FPSVSL---------KQLVALPRDE 474
Cdd:PRK10584 39 IALIGESGSGKSTLLAILAGLDDGSSGEVsLVGQPLHQMDEEARAKlrakhvgfvFQSFMLiptlnalenVELPALLRGE 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 475 GDFNDLAVA-AVLHEAGLGefiERMKDADAGnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK10584 119 SSRQSRNGAkALLEQLGLG---KRLDHLPAQ-------LSGGEQQRVALARAFNGRPDVLFADEPTGNLD 178
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
398-597 |
3.46e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 54.99 E-value: 3.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 398 TPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIypqgASSLYVPQEAKFPSVSLKQLVALPRDEGDF 477
Cdd:PRK13644 15 TPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVL----VSGIDTGDFSKLQGIRKLVGIVFQNPETQF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 ------NDLA----------------VAAVLHEAGLGEFIERmkdadagnSPwdMVLSGGQKQKVMLARILLHKPSIIFL 535
Cdd:PRK13644 91 vgrtveEDLAfgpenlclppieirkrVDRALAEIGLEKYRHR--------SP--KTLSGGQGQCVALAGILTMEPECLIF 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 536 DEATGALDPASKL-------RFHTALKT---------RCPDAIVVSIMHEEKLPTLESGESIFShvlDIANGYVSLIP 597
Cdd:PRK13644 161 DEVTSMLDPDSGIavlerikKLHEKGKTivyithnleELHDADRIIVMDRGKIVLEGEPENVLS---DVSLQTLGLTP 235
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
399-543 |
3.72e-08 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 54.71 E-value: 3.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 399 PFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYVPQ-EAKFPSVSLK------ 465
Cdd:PRK11248 15 PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSItldgkpVEGPGAERGVVFQnEGLLPWRNVQdnvafg 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 466 -QLVALPRDEgdfnDLAVA-AVLHEAGLGEFIERMkdadagnsPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11248 95 lQLAGVEKMQ----RLEIAhQMLKKVGLEGAEKRY--------IWQ--LSGGQRQRVGIARALAANPQLLLLDEPFGALD 160
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
418-554 |
4.18e-08 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 53.82 E-value: 4.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY---PQGASSL----YVPQE-AKFPSVSLK-QLVALprdeGDFNDLAVAAVLHE 488
Cdd:cd03269 33 GPNGAGKTTTIRMILGIILPDSGEVLFdgkPLDIAARnrigYLPEErGLYPKMKVIdQLVYL----AQLKGLKKEEARRR 108
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 489 AGlgEFIERMKDADAGNSPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTAL 554
Cdd:cd03269 109 ID--EWLERLELSEYANKRVEE-LSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVI 171
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
394-568 |
5.18e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 54.61 E-value: 5.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 394 PASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSLYVPQEAK------------FP 460
Cdd:PRK13632 18 PNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIkIDGITISKENLKEIRKkigiifqnpdnqFI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 461 SVSLKQLVA-------LPRDEGD--FNDLAvaavlHEAGLGEFIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPS 531
Cdd:PRK13632 98 GATVEDDIAfglenkkVPPKKMKdiIDDLA-----KKVGMEDYLDK--------EPQN--LSGGQKQRVAIASVLALNPE 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 974659840 532 IIFLDEATGALDPASK---------LRfHTALKTrcpdaiVVSIMH 568
Cdd:PRK13632 163 IIIFDESTSMLDPKGKreikkimvdLR-KTRKKT------LISITH 201
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
418-555 |
5.32e-08 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 55.58 E-value: 5.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGL--WPYGTGNIIYPQG--ASSLYV------------------PQEAKFPSVS------------ 463
Cdd:TIGR03269 33 GRSGAGKSVLMHVLRGMdqYEPTSGRIIYHVAlcEKCGYVerpskvgepcpvcggtlePEEVDFWNLSdklrrrirkria 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 464 --LKQLVALPRDEGDFNDlaVAAVLHEAGL--GEFIERMKDAdagnspWDMV------------LSGGQKQKVMLARILL 527
Cdd:TIGR03269 113 imLQRTFALYGDDTVLDN--VLEALEEIGYegKEAVGRAVDL------IEMVqlshrithiardLSGGEKQRVVLARQLA 184
|
170 180
....*....|....*....|....*...
gi 974659840 528 HKPSIIFLDEATGALDPASKLRFHTALK 555
Cdd:TIGR03269 185 KEPFLFLADEPTGTLDPQTAKLVHNALE 212
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
512-545 |
5.86e-08 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 55.08 E-value: 5.86e-08
10 20 30
....*....|....*....|....*....|....
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:COG1135 141 LSGGQKQRVGIARALANNPKVLLCDEATSALDPE 174
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
351-555 |
6.23e-08 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 55.67 E-value: 6.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 351 AQSIESVQePAEFYARSGVN---RFAFTHQHPRFGLSVRNLTlmQGPASETPFlRSGVINMRAGDWIYMRGESGSGKTSF 427
Cdd:PRK15064 286 AKQIDKIK-LEEVKPSSRQNpfiRFEQDKKLHRNALEVENLT--KGFDNGPLF-KNLNLLLEAGERLAIIGENGVGKTTL 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 428 IKALNGLWPYGTGNIIYPQGASSLYVPQ--EAKFPS-VSLKQLVALPRDEGDfNDLAVAAVLheaglGefieRM---KDa 501
Cdd:PRK15064 362 LRTLVGELEPDSGTVKWSENANIGYYAQdhAYDFENdLTLFDWMSQWRQEGD-DEQAVRGTL-----G----RLlfsQD- 430
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 974659840 502 DAGNSPwdMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALK 555
Cdd:PRK15064 431 DIKKSV--KVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMESIESLNMALE 482
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
418-546 |
6.84e-08 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 53.73 E-value: 6.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNI-IYPQGASSL-------------YVPQE---------------AKFPSVSLKQLV 468
Cdd:cd03256 34 GPSGAGKSTLLRCLNGLVEPTSGSVlIDGTDINKLkgkalrqlrrqigMIFQQfnlierlsvlenvlsGRLGRRSTWRSL 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 469 ALPRDEGDFNdLAVAAvLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:cd03256 114 FGLFPKEEKQ-RALAA-LERVGLLDKAYQRADQ----------LSGGQQQRVAIARALMQQPKLILADEPVASLDPAS 179
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
482-543 |
7.05e-08 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 55.60 E-value: 7.05e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 482 VAAVLHEAGLGEFIERMKDAdagnspWD-MV------LSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:COG5265 464 VEAAARAAQIHDFIESLPDG------YDtRVgerglkLSGGEKQRVAIARTLLKNPPILIFDEATSALD 526
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
406-558 |
7.27e-08 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 53.84 E-value: 7.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLwpygtgniIYPQGASSLYVPQEAKfpSVSLKQLVALPRDEG----DFNDL- 480
Cdd:TIGR02315 23 LNINPGEFVAIIGPSGAGKSTLLRCINRL--------VEPSSGSILLEGTDIT--KLRGKKLRKLRRRIGmifqHYNLIe 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 481 ---AVAAVLH---------EAGLGEF-----------IERMKDADAGNSPWDMvLSGGQKQKVMLARILLHKPSIIFLDE 537
Cdd:TIGR02315 93 rltVLENVLHgrlgykptwRSLLGRFseedkeralsaLERVGLADKAYQRADQ-LSGGQQQRVAIARALAQQPDLILADE 171
|
170 180
....*....|....*....|.
gi 974659840 538 ATGALDPASKLRFHTALKTRC 558
Cdd:TIGR02315 172 PIASLDPKTSKQVMDYLKRIN 192
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
398-543 |
8.09e-08 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 53.67 E-value: 8.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 398 TPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYP-QGASSLYVPQEAKFPSVSLKQLVALPRDEGD 476
Cdd:PRK11629 22 TDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNgQPMSKLSSAAKAELRNQKLGFIYQFHHLLPD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 477 FNDLA-VAAVLheaglgeFIERMKDADAGNSPWDMV---------------LSGGQKQKVMLARILLHKPSIIFLDEATG 540
Cdd:PRK11629 102 FTALEnVAMPL-------LIGKKKPAEINSRALEMLaavglehranhrpseLSGGERQRVAIARALVNNPRLVLADEPTG 174
|
...
gi 974659840 541 ALD 543
Cdd:PRK11629 175 NLD 177
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
409-549 |
1.05e-07 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 53.05 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIiYPQGASSLYVP----------QEAK-FPSVSLKQLVALPRDEG-- 475
Cdd:PRK10771 23 ERGERVAILGPSGAGKSTLLNLIAGFLTPASGSL-TLNGQDHTTTPpsrrpvsmlfQENNlFSHLTVAQNIGLGLNPGlk 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 476 --DFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPAskLR 549
Cdd:PRK10771 102 lnAAQREKLHAIARQMGIEDLLARLPGQ----------LSGGQRQRVALARCLVREQPILLLDEPFSALDPA--LR 165
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
409-571 |
1.05e-07 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 53.21 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALnglwpYGT-----GNIIYPQGASSL-------------------YVPQeakF----P 460
Cdd:COG4778 35 AAGECVALTGPSGAGKSTLLKCI-----YGNylpdsGSILVRHDGGWVdlaqaspreilalrrrtigYVSQ---FlrviP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 461 SVSLKQLVALP-RDEGdfndLAVAAVLHEAGlgEFIERMkdadagNSP---WDM---VLSGGQKQKVMLARILLHKPSII 533
Cdd:COG4778 107 RVSALDVVAEPlLERG----VDREEARARAR--ELLARL------NLPerlWDLppaTFSGGEQQRVNIARGFIADPPLL 174
|
170 180 190
....*....|....*....|....*....|....*...
gi 974659840 534 FLDEATGALDPASKlrfhtalktrcpdAIVVSIMHEEK 571
Cdd:COG4778 175 LLDEPTASLDAANR-------------AVVVELIEEAK 199
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
418-581 |
1.10e-07 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 54.72 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIiYPQG--ASSL----------YVPQEAKFPSVSLKQLVALPRDegdFNDLAVAAV 485
Cdd:PRK10790 374 GHTGSGKSTLASLLMGYYPLTEGEI-RLDGrpLSSLshsvlrqgvaMVQQDPVVLADTFLANVTLGRD---ISEEQVWQA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 486 LHEAGLGEFIERMKDA------DAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCP 559
Cdd:PRK10790 450 LETVQLAELARSLPDGlytplgEQGNN-----LSVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVRE 524
|
170 180
....*....|....*....|..
gi 974659840 560 DAIVVSIMHeeKLPTLESGESI 581
Cdd:PRK10790 525 HTTLVVIAH--RLSTIVEADTI 544
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
512-545 |
1.31e-07 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 54.04 E-value: 1.31e-07
10 20 30
....*....|....*....|....*....|....
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:PRK11153 141 LSGGQKQRVAIARALASNPKVLLCDEATSALDPA 174
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
418-544 |
1.40e-07 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 52.69 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpqGASSLYVPQEAK----------------FPSVSLKQLVAL--------PRD 473
Cdd:COG1126 34 GPSGSGKSTLLRCINLLEEPDSGTITV--DGEDLTDSKKDInklrrkvgmvfqqfnlFPHLTVLENVTLapikvkkmSKA 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 474 EGDfnDLAVAAvLHEAGLGEFiermKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG1126 112 EAE--ERAMEL-LERVGLADK----ADAYPAQ------LSGGQQQRVAIARALAMEPKVMLFDEPTSALDP 169
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
407-545 |
1.42e-07 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 52.57 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 407 NMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPSVSLKQLVA---LPRDEGDFNDLAVA 483
Cdd:PRK10908 24 HMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQdhhLLMDRTVYDNVAIP 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 484 AVLHEAGlGEFIERMKDA---------DAGNSPwdMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:PRK10908 104 LIIAGAS-GDDIRRRVSAaldkvglldKAKNFP--IQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDA 171
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
383-539 |
1.48e-07 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 52.53 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGA--SSL--------- 451
Cdd:TIGR03410 1 LEVSNLNVYYG---QSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRL-DGEdiTKLppherarag 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 --YVPQ--EAkFPSVSLKQ-----LVALPRDEGDFNDLAVA--AVLHEaglgefierMKDADAGNspwdmvLSGGQKQKV 520
Cdd:TIGR03410 77 iaYVPQgrEI-FPRLTVEEnlltgLAALPRRSRKIPDEIYElfPVLKE---------MLGRRGGD------LSGGQQQQL 140
|
170
....*....|....*....
gi 974659840 521 MLARILLHKPSIIFLDEAT 539
Cdd:TIGR03410 141 AIARALVTRPKLLLLDEPT 159
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
418-569 |
1.61e-07 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 52.37 E-value: 1.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQEAK------------FPSVSLKQLVA-------LPRDEgdFN 478
Cdd:cd03266 38 GPNGAGKTTTLRMLAGLLEPDAGFATV-DGFDVVKEPAEARrrlgfvsdstglYDRLTARENLEyfaglygLKGDE--LT 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 479 DlAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRC 558
Cdd:cd03266 115 A-RLEELADRLGMEELLDRRVGG----------FSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLR 183
|
170
....*....|....*
gi 974659840 559 PD--AIVVS--IMHE 569
Cdd:cd03266 184 ALgkCILFSthIMQE 198
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
414-546 |
1.62e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 54.17 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 414 IYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKF-PSVSLKQLV---------ALPR-DE-------- 474
Cdd:TIGR03719 34 IGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQPGIKVGYLPQEPQLdPTKTVRENVeegvaeikdALDRfNEisakyaep 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 475 -GDFNDLAvaavlheAGLGEFIERMKDADAGN--------------SPWDM---VLSGGQKQKVMLARILLHKPSIIFLD 536
Cdd:TIGR03719 114 dADFDKLA-------AEQAELQEIIDAADAWDldsqleiamdalrcPPWDAdvtKLSGGERRRVALCRLLLSKPDMLLLD 186
|
170
....*....|
gi 974659840 537 EATGALDPAS 546
Cdd:TIGR03719 187 EPTNHLDAES 196
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
416-568 |
1.85e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 52.79 E-value: 1.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 416 MRGESGSGKTSFIKALNGL------WPYgTGNIIYpqGASSLYVPQEA---------------KFPSVSLKQLVA----- 469
Cdd:PRK14271 52 LMGPTGSGKTTFLRTLNRMndkvsgYRY-SGDVLL--GGRSIFNYRDVlefrrrvgmlfqrpnPFPMSIMDNVLAgvrah 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 --LPRDEgdFNDLAvAAVLHEAGLGEFI-ERMKDadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:PRK14271 129 klVPRKE--FRGVA-QARLTEVGLWDAVkDRLSD-----SPFR--LSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTT 198
|
170 180
....*....|....*....|..
gi 974659840 547 KLRFHTALKTRCPDAIVVSIMH 568
Cdd:PRK14271 199 TEKIEEFIRSLADRLTVIIVTH 220
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
406-543 |
2.01e-07 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 52.42 E-value: 2.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKFPSvslkqlvALPRDEGDFNDLAVAav 485
Cdd:PRK09544 25 LELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQKLYLDT-------TLPLTVNRFLRLRPG-- 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 486 LHEAGLGEFIERMKDADAGNSPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK09544 96 TKKEDILPALKRVQAGHLIDAPMQK-LSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
418-568 |
3.78e-07 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 51.71 E-value: 3.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKA---LNGLWP--YGTGNIIYpqGASSLYVPQeakFPSVSLKQLVAL------PRDEGDFNDLAVAAVL 486
Cdd:PRK14243 43 GPSGCGKSTILRCfnrLNDLIPgfRVEGKVTF--HGKNLYAPD---VDPVEVRRRIGMvfqkpnPFPKSIYDNIAYGARI 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 487 --HEAGLGEFIER-MKDAdagnSPWDMV----------LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTA 553
Cdd:PRK14243 118 ngYKGDMDELVERsLRQA----ALWDEVkdklkqsglsLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEEL 193
|
170
....*....|....*
gi 974659840 554 LKTRCPDAIVVSIMH 568
Cdd:PRK14243 194 MHELKEQYTIIIVTH 208
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
383-543 |
3.81e-07 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 53.17 E-value: 3.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASETPFLRSGV-INMRAGDWIYMRGESGSGKTsfIKALNGLWPYGTGNIIYPQG-----ASSLYVPQE 456
Cdd:PRK15134 6 LAIENLSVAFRQQQTVRTVVNDVsLQIEAGETLALVGESGSGKS--VTALSILRLLPSPPVVYPSGdirfhGESLLHASE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 457 AKF--------------PSVSLKQLVALPRDegdfndLAVAAVLH-----EAGLGEFI---ERMKDADAGNSPWDM--VL 512
Cdd:PRK15134 84 QTLrgvrgnkiamifqePMVSLNPLHTLEKQ------LYEVLSLHrgmrrEAARGEILnclDRVGIRQAAKRLTDYphQL 157
|
170 180 190
....*....|....*....|....*....|.
gi 974659840 513 SGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK15134 158 SGGERQRVMIAMALLTRPELLIADEPTTALD 188
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
397-547 |
3.94e-07 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 52.01 E-value: 3.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 397 ETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWP--YGTGNI-----------------IYPQGASsLYVPQEA 457
Cdd:TIGR01188 5 DFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRptSGTARVagydvvreprkvrrsigIVPQYAS-VDEDLTG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 458 KFPSVSLKQLVALPRDEGdfndlavaavlhEAGLGEFIERMKDADAGNSPWDmVLSGGQKQKVMLARILLHKPSIIFLDE 537
Cdd:TIGR01188 84 RENLEMMGRLYGLPKDEA------------EERAEELLELFELGEAADRPVG-TYSGGMRRRLDIAASLIHQPDVLFLDE 150
|
170
....*....|
gi 974659840 538 ATGALDPASK 547
Cdd:TIGR01188 151 PTTGLDPRTR 160
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
418-545 |
4.00e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 52.16 E-value: 4.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWP--YGT--------GNIIYPQGASSLYVPQEAK--------------FPSVSL------KQL 467
Cdd:PRK13631 59 GNSGSGKSTLVTHFNGLIKskYGTiqvgdiyiGDKKNNHELITNPYSKKIKnfkelrrrvsmvfqFPEYQLfkdtieKDI 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 468 ----VALPRDEGDFNDLAvAAVLHEAGLGE-FIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:PRK13631 139 mfgpVALGVKKSEAKKLA-KFYLNKMGLDDsYLER--------SPFG--LSGGQKRRVAIAGILAIQPEILIFDEPTAGL 207
|
...
gi 974659840 543 DPA 545
Cdd:PRK13631 208 DPK 210
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
418-543 |
4.50e-07 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 51.98 E-value: 4.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYG---TGNIIYpQGA--SSL--------------YVPQEakfPSVSL-------KQL---- 467
Cdd:COG0444 38 GESGSGKSTLARAILGLLPPPgitSGEILF-DGEdlLKLsekelrkirgreiqMIFQD---PMTSLnpvmtvgDQIaepl 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 468 -VALPRDEGDFNDLAVAAvLHEAGLGEFIERMKDadagnSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:COG0444 114 rIHGGLSKAEARERAIEL-LERVGLPDPERRLDR-----YPHE--LSGGMRQRVMIARALALEPKLLIADEPTTALD 182
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
408-556 |
4.89e-07 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 51.12 E-value: 4.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 408 MRAGDWIYMRGESGSGKTSFIKALNGLWPYG---TGNIIYPQGASSL--------YVPQEAKF-PSVSLKQLV------A 469
Cdd:cd03234 30 VESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNGQPRKPdqfqkcvaYVRQDDILlPGLTVRETLtytailR 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 LPRDEGDFNDLAVAAVLHEAGLGefiermkDADAGNSpwDMV-LSGGQKQKVMLARILLHKPSIIFLDEATGALDPaskl 548
Cdd:cd03234 110 LPRKSSDAIRKKRVEDVLLRDLA-------LTRIGGN--LVKgISGGERRRVSIAVQLLWDPKVLILDEPTSGLDS---- 176
|
....*...
gi 974659840 549 rfHTALKT 556
Cdd:cd03234 177 --FTALNL 182
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
406-549 |
5.06e-07 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 51.19 E-value: 5.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYP-QGASSLYVPQE---------AKFPSVSLKQLVAL----- 470
Cdd:cd03296 23 LDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGgEDATDVPVQERnvgfvfqhyALFRHMTVFDNVAFglrvk 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 471 PRDEGDfNDLAVAAVLHEagLGEFIERMKDADAGNSPwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDpaSKLR 549
Cdd:cd03296 103 PRSERP-PEAEIRAKVHE--LLKLVQLDWLADRYPAQ----LSGGQRQRVALARALAVEPKVLLLDEPFGALD--AKVR 172
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
407-572 |
5.44e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 52.52 E-value: 5.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 407 NMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGAsslyvPQEAKFPSVSLKQLVAL-PRD---EGDFNDLAV 482
Cdd:TIGR02633 282 SLRRGEILGVAGLVGAGRTELVQALFGAYPGKFEGNVFINGK-----PVDIRNPAQAIRAGIAMvPEDrkrHGIVPILGV 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 483 AAVLHEAGLGEFIERMKDADAGN----------------SPWDMV--LSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:TIGR02633 357 GKNITLSVLKSFCFKMRIDAAAElqiigsaiqrlkvktaSPFLPIgrLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDV 436
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 974659840 545 ASK---LRFHTALKTRCPDAIVVS--------------IMHEEKL 572
Cdd:TIGR02633 437 GAKyeiYKLINQLAQEGVAIIVVSselaevlglsdrvlVIGEGKL 481
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
418-549 |
6.12e-07 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 51.19 E-value: 6.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLW---PYG--TGNI------IYPQGAS--SL-----YVPQeaK---FPSvSLKQLVALP----- 471
Cdd:COG1117 44 GPSGCGKSTLLRCLNRMNdliPGArvEGEIlldgedIYDPDVDvvELrrrvgMVFQ--KpnpFPK-SIYDNVAYGlrlhg 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 472 -RDEGDFNDLaVAAVLHEAGLgefiermkdadagnspWDMV----------LSGGQKQKVMLARILLHKPSIIFLDEATG 540
Cdd:COG1117 121 iKSKSELDEI-VEESLRKAAL----------------WDEVkdrlkksalgLSGGQQQRLCIARALAVEPEVLLMDEPTS 183
|
....*....
gi 974659840 541 ALDPASKLR 549
Cdd:COG1117 184 ALDPISTAK 192
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
406-548 |
6.75e-07 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 50.66 E-value: 6.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSL------------YVPQEAK-FPSVSL-KQLVALP 471
Cdd:PRK10895 24 LTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLlplhararrgigYLPQEASiFRRLSVyDNLMAVL 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 472 RDEGDFNDLAVAAVLHEAgLGEF-IERMKDaDAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKL 548
Cdd:PRK10895 104 QIRDDLSAEQREDRANEL-MEEFhIEHLRD-SMGQS-----LSGGERRRVEIARALAANPKFILLDEPFAGVDPISVI 174
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
417-550 |
6.91e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 50.26 E-value: 6.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 417 RGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAkfpSVSLKQLVALPrdegdfNDLAVAAVL---------H 487
Cdd:PRK13539 34 TGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEA---CHYLGHRNAMK------PALTVAENLefwaaflggE 104
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 974659840 488 EAGLGEFIERMKDADAGNSPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRF 550
Cdd:PRK13539 105 ELDIAAALEAVGLAPLAHLPFGY-LSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALF 166
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
418-568 |
7.86e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 50.68 E-value: 7.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALN---GLWP--------YGTGNIIYPQGASSLYVPQEAKF------PSVSLKQLVALPRDegdFNDL 480
Cdd:PRK14247 36 GPSGSGKSTLLRVFNrliELYPearvsgevYLDGQDIFKMDVIELRRRVQMVFqipnpiPNLSIFENVALGLK---LNRL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 481 A---------VAAVLHEAGLGEFIERMKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:PRK14247 113 VkskkelqerVRWALEKAQLWDEVKDRLDAPAGK------LSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIE 186
|
170
....*....|....*..
gi 974659840 552 TALKTRCPDAIVVSIMH 568
Cdd:PRK14247 187 SLFLELKKDMTIVLVTH 203
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
403-590 |
1.07e-06 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 51.73 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 403 SGVINMRAGD-WIYM--RGESGSGK-TSFIKALN---GLWPYGT--GNIiypQGASSLYVPQE-AKFPSVSLKQLVALPR 472
Cdd:TIGR03269 338 SGEVNVRVGDeWVDMtkPGPDGRGRaKRYIGILHqeyDLYPHRTvlDNL---TEAIGLELPDElARMKAVITLKMVGFDE 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 473 DEGDfndlavaavlheaglgEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLrfht 552
Cdd:TIGR03269 415 EKAE----------------EILDKYPDE----------LSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKV---- 464
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 974659840 553 alktrcpdAIVVSIMHEEKlptlESGES--IFSHVLDIAN 590
Cdd:TIGR03269 465 --------DVTHSILKARE----EMEQTfiIVSHDMDFVL 492
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
418-568 |
1.14e-06 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 50.23 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGT-----------GNIIYPQGASSLYVPQEA--------KFPSVSLKQLVA-------LP 471
Cdd:PRK14267 37 GPSGCGKSTLLRTFNRLLELNEearvegevrlfGRNIYSPDVDPIEVRREVgmvfqypnPFPHLTIYDNVAigvklngLV 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 472 RDEGDFNDLAVAAVLHEAGLGEFIERMKDAdAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:PRK14267 117 KSKKELDERVEWALKKAALWDEVKDRLNDY-PSN------LSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIE 189
|
170
....*....|....*..
gi 974659840 552 TALKTRCPDAIVVSIMH 568
Cdd:PRK14267 190 ELLFELKKEYTIVLVTH 206
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
383-572 |
1.34e-06 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 50.19 E-value: 1.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLT------LMQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYP-QGASSLYVPQ 455
Cdd:TIGR02769 3 LEVRDVThtyrtgGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRgQDLYQLDRKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 456 EAKF----------------PSVSLKQLVALP-RDEGDFNDLA----VAAVLHEAGLgefiermKDADAGNSPWDmvLSG 514
Cdd:TIGR02769 83 RRAFrrdvqlvfqdspsavnPRMTVRQIIGEPlRHLTSLDESEqkarIAELLDMVGL-------RSEDADKLPRQ--LSG 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 515 GQKQKVMLARILLHKPSIIFLDEATGALD---PASKLRFHTALKTRCPDAIVVsIMHEEKL 572
Cdd:TIGR02769 154 GQLQRINIARALAVKPKLIVLDEAVSNLDmvlQAVILELLRKLQQAFGTAYLF-ITHDLRL 213
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
406-548 |
1.53e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 50.08 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRA--GDWIYMRGESGSGKTSFIKALNGlwpygtgnIIYPQGASSLYVPQEAKFPSVSL---KQLVALPRDEGDfNDL 480
Cdd:PRK13639 21 INFKAekGEMVALLGPNGAGKSTLFLHFNG--------ILKPTSGEVLIKGEPIKYDKKSLlevRKTVGIVFQNPD-DQL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 481 AVAAVLHEAGLG---------EFIERMKDA--DAGNSPWDMV----LSGGQKQKVMLARILLHKPSIIFLDEATGALDP- 544
Cdd:PRK13639 92 FAPTVEEDVAFGplnlglskeEVEKRVKEAlkAVGMEGFENKpphhLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPm 171
|
....*
gi 974659840 545 -ASKL 548
Cdd:PRK13639 172 gASQI 176
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
401-568 |
1.59e-06 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 51.48 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 401 LRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQ------GASSL-----YVPQEAKFPSVSLKqlva 469
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGlniakiGLHDLrfkitIIPQDPVLFSGSLR---- 1377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 LPRDE-GDFNDLAVAAVLHEAGLGEFIERMKD------ADAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:TIGR00957 1378 MNLDPfSQYSDEEVWWALELAHLKTFVSALPDkldhecAEGGEN-----LSVGQRQLVCLARALLRKTKILVLDEATAAV 1452
|
170 180
....*....|....*....|....*.
gi 974659840 543 DPASKLRFHTALKTRCPDAIVVSIMH 568
Cdd:TIGR00957 1453 DLETDNLIQSTIRTQFEDCTVLTIAH 1478
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
418-543 |
1.87e-06 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 50.84 E-value: 1.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGtGNIIYpQGASSLYVPQEAKFPSVSLKQLV------AL-PR-------DEGdfndLAVa 483
Cdd:COG4172 319 GESGSGKSTLGLALLRLIPSE-GEIRF-DGQDLDGLSRRALRPLRRRMQVVfqdpfgSLsPRmtvgqiiAEG----LRV- 391
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 484 avlHEAGLG--EFIERMKDA--DAGNSPWDMV-----LSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:COG4172 392 ---HGPGLSaaERRARVAEAleEVGLDPAARHrypheFSGGQRQRIAIARALILEPKLLVLDEPTSALD 457
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
418-543 |
2.20e-06 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 50.50 E-value: 2.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKF-PSVSLKQLV---------ALPRdegdFNDLAVAAVLH 487
Cdd:PRK11819 40 GLNGAGKSTLLRIMAGVDKEFEGEARPAPGIKVGYLPQEPQLdPEKTVRENVeegvaevkaALDR----FNEIYAAYAEP 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 488 EAGLGEFIERMKD-------ADAGNS--------------PWDM---VLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11819 116 DADFDALAAEQGElqeiidaADAWDLdsqleiamdalrcpPWDAkvtKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
407-549 |
2.47e-06 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 49.95 E-value: 2.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 407 NMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQE-----------AKFPSVSLKQLVA------ 469
Cdd:PRK09452 36 TINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIML-DGQDITHVPAEnrhvntvfqsyALFPHMTVFENVAfglrmq 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 470 -LPRDEgdfndlaVAAVLHEA----GLGEFIERmKDADagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDp 544
Cdd:PRK09452 115 kTPAAE-------ITPRVMEAlrmvQLEEFAQR-KPHQ---------LSGGQQQRVAIARAVVNKPKVLLLDESLSALD- 176
|
....*
gi 974659840 545 aSKLR 549
Cdd:PRK09452 177 -YKLR 180
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
394-587 |
2.61e-06 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 50.21 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 394 PASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNII--------YPQGA---SSLYVPQEAKFPSV 462
Cdd:PRK11160 349 PDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILlngqpiadYSEAAlrqAISVVSQRVHLFSA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQ--LVALPrdegDFNDLAVAAVLHEAGLGEFIERMKDADA----GNSPwdmvLSGGQKQKVMLARILLHKPSIIFLD 536
Cdd:PRK11160 429 TLRDnlLLAAP----NASDEALIEVLQQVGLEKLLEDDKGLNAwlgeGGRQ----LSGGEQRRLGIARALLHDAPLLLLD 500
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 974659840 537 EATGALDPASKLRFHTALKTRCPDAIVVSIMHeeKLPTLESGESIfsHVLD 587
Cdd:PRK11160 501 EPTEGLDAETERQILELLAEHAQNKTVLMITH--RLTGLEQFDRI--CVMD 547
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
512-582 |
2.86e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 50.80 E-value: 2.86e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMHEEKLPTLESGESIF 582
Cdd:PTZ00265 580 LSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRLSTIRYANTIF 650
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
407-548 |
2.90e-06 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 48.52 E-value: 2.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 407 NMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQEAK------FPSVSLK-------------QL 467
Cdd:cd03265 22 RVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATV-AGHDVVREPREVRrrigivFQDLSVDdeltgwenlyihaRL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 468 VALPRDEGDFNdlaVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:cd03265 101 YGVPGAERRER---IDELLDFVGLLEAADRLVKT----------YSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTR 167
|
.
gi 974659840 548 L 548
Cdd:cd03265 168 A 168
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
468-545 |
3.00e-06 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 48.58 E-value: 3.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 468 VALP---RDEGDFNDLAvAAVLHEAGLGEfieRMKDADAGnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG4181 111 VMLPlelAGRRDARARA-RALLERVGLGH---RLDHYPAQ-------LSGGEQQRVALARAFATEPAILFADEPTGNLDA 179
|
.
gi 974659840 545 A 545
Cdd:COG4181 180 A 180
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
418-543 |
3.02e-06 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 49.49 E-value: 3.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLwpygtgniIYPQ-GASSL----------------------YVPQEAK-FP--SV--SLKQLVA 469
Cdd:PRK11144 31 GRSGAGKTSLINAISGL--------TRPQkGRIVLngrvlfdaekgiclppekrrigYVFQDARlFPhyKVrgNLRYGMA 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 470 lPRDEGDFNDlaVAAVLheaGLGEFIERMkdadagnsPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11144 103 -KSMVAQFDK--IVALL---GIEPLLDRY--------PGS--LSGGEKQRVAIGRALLTAPELLLMDEPLASLD 160
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
411-550 |
3.19e-06 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 48.41 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 411 GDWIYMRGESGSGKTSFIKALNGLWPYGTGNIiYPQGASSLYVPQE-----------AKFPSVSLKQLVAL-------PR 472
Cdd:cd03301 26 GEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRI-YIGGRDVTDLPPKdrdiamvfqnyALYPHMTVYDNIAFglklrkvPK 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 473 DEGDFNDLAVAAVLheaGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDpaSKLRF 550
Cdd:cd03301 105 DEIDERVREVAELL---QIEHLLDRKPKQ----------LSGGQRQRVALGRAIVREPKVFLMDEPLSNLD--AKLRV 167
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
398-595 |
3.22e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 49.25 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 398 TPFLRSGV----INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSLYVPQEAK------FPS 461
Cdd:PRK13634 16 TPFERRALydvnVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVtigervITAGKKNKKLKPLRKKvgivfqFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 VSL------KQLVALPRDEGDFNDLA---VAAVLHEAGLGE-FIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPS 531
Cdd:PRK13634 96 HQLfeetveKDICFGPMNFGVSEEDAkqkAREMIELVGLPEeLLAR--------SPFE--LSGGQMRRVAIAGVLAMEPE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 532 IIFLDEATGALDPASKL-------RFH------TALKT-------RCPDAIVVsiMHEEKLPTLESGESIFSHVLDIANG 591
Cdd:PRK13634 166 VLVLDEPTAGLDPKGRKemmemfyKLHkekgltTVLVThsmedaaRYADQIVV--MHKGTVFLQGTPREIFADPDELEAI 243
|
....
gi 974659840 592 YVSL 595
Cdd:PRK13634 244 GLDL 247
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
512-549 |
3.25e-06 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 49.37 E-value: 3.25e-06
10 20 30
....*....|....*....|....*....|....*...
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDpaSKLR 549
Cdd:COG1118 134 LSGGQRQRVALARALAVEPEVLLLDEPFGALD--AKVR 169
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
418-585 |
3.84e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 48.85 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY-----PQGASSLyvpQEAK-----------FPSVSLKQlVALPRDEGdFNDLA 481
Cdd:PRK13645 44 GTTGSGKSTMIQLTNGLIISETGQTIVgdyaiPANLKKI---KEVKrlrkeiglvfqFPEYQLFQ-ETIEKDIA-FGPVN 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 482 VAAVLHEA--GLGEFIE--RMKDADAGNSPWDmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK-------LRF 550
Cdd:PRK13645 119 LGENKQEAykKVPELLKlvQLPEDYVKRSPFE--LSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEedfinlfERL 196
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 974659840 551 HTALKTR-------------CPDAIVVsiMHEEKLPTLESGESIFSHV 585
Cdd:PRK13645 197 NKEYKKRiimvthnmdqvlrIADEVIV--MHEGKVISIGSPFEIFSNQ 242
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
418-545 |
3.91e-06 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 47.04 E-value: 3.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIiYPQGasslyvpQEAKFPSvslkqlvalPRDEgdfndlavaavlHEAGLGefier 497
Cdd:cd03216 33 GENGAGKSTLMKILSGLYKPDSGEI-LVDG-------KEVSFAS---------PRDA------------RRAGIA----- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 974659840 498 mkdadagnspwdMV--LSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:cd03216 79 ------------MVyqLSVGERQMVEIARALARNARLLILDEPTAALTPA 116
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
409-556 |
4.21e-06 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 49.57 E-value: 4.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------IYPQGASSL-----YVPQEAKFPSVSLKQLVALPRDEGDF 477
Cdd:PRK13657 359 KPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRIlidgtdIRTVTRASLrrniaVVFQDAGLFNRSIEDNIRVGRPDATD 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 478 NDLAVAAVLHEAGlgEFIERMKD------ADAGNSpwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:PRK13657 439 EEMRAAAERAQAH--DFIERKPDgydtvvGERGRQ-----LSGGERQRLAIARALLKDPPILILDEATSALDVETEAKVK 511
|
....*
gi 974659840 552 TALKT 556
Cdd:PRK13657 512 AALDE 516
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
512-544 |
4.31e-06 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 48.59 E-value: 4.31e-06
10 20 30
....*....|....*....|....*....|...
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:PRK11264 145 LSGGQQQRVAIARALAMRPEVILFDEPTSALDP 177
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
512-560 |
4.86e-06 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 48.10 E-value: 4.86e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPD 560
Cdd:cd03267 154 LSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRE 202
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
418-569 |
5.27e-06 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 48.49 E-value: 5.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGT-----------GNIIYPQGAS--------SLYVPQEAKFPsVSLKQLVAL-------- 470
Cdd:PRK14258 40 GPSGCGKSTFLKCLNRMNELESevrvegrveffNQNIYERRVNlnrlrrqvSMVHPKPNLFP-MSVYDNVAYgvkivgwr 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 471 PRDEGDfnDLAVAAVlheaglgefiermKDADAgnspWDMV----------LSGGQKQKVMLARILLHKPSIIFLDEATG 540
Cdd:PRK14258 119 PKLEID--DIVESAL-------------KDADL----WDEIkhkihksaldLSGGQQQRLCIARALAVKPKVLLMDEPCF 179
|
170 180 190
....*....|....*....|....*....|....
gi 974659840 541 ALDPASKLRFHT-----ALKTRCPDAIVVSIMHE 569
Cdd:PRK14258 180 GLDPIASMKVESliqslRLRSELTMVIVSHNLHQ 213
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
383-551 |
5.54e-06 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 47.04 E-value: 5.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTlmqGPASETPF---LRSGVInmrAGdwIYmrGESGSGKTSFIKALNGLWPYGTGNIIYpQGasslyVPQEAKF 459
Cdd:cd03215 5 LEVRGLS---VKGAVRDVsfeVRAGEI---VG--IA--GLVGNGQTELAEALFGLRPPASGEITL-DG-----KPVTRRS 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 460 PSVSLKQLVAL-PRD---EGDFNDLAVAavlHEAGLGEFiermkdadagnspwdmvLSGGQKQKVMLARILLHKPSIIFL 535
Cdd:cd03215 69 PRDAIRAGIAYvPEDrkrEGLVLDLSVA---ENIALSSL-----------------LSGGNQQKVVLARWLARDPRVLIL 128
|
170
....*....|....*.
gi 974659840 536 DEATGALDPASKLRFH 551
Cdd:cd03215 129 DEPTRGVDVGAKAEIY 144
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
512-544 |
6.16e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 48.16 E-value: 6.16e-06
10 20 30
....*....|....*....|....*....|...
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:PRK13633 145 LSGGQKQRVAIAGILAMRPECIIFDEPTAMLDP 177
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
406-543 |
6.24e-06 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 49.35 E-value: 6.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpqGASSL-------------YVPQEAKFPSVSLKQLVALPR 472
Cdd:TIGR01193 495 LTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILL--NGFSLkdidrhtlrqfinYLPQEPYIFSGSILENLLLGA 572
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 473 DEGDFNDLAVAAVlHEAGLGEFIERMK-------DADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:TIGR01193 573 KENVSQDEIWAAC-EIAEIKDDIENMPlgyqtelSEEGSS------ISGGQKQRIALARALLTDSKVLILDESTSNLD 643
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
506-555 |
7.37e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 48.24 E-value: 7.37e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 974659840 506 SPWDMvlSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALK 555
Cdd:PRK13646 142 SPFQM--SGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLK 189
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
421-539 |
9.90e-06 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 48.48 E-value: 9.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 421 GSGKTSFIKALNGLWPYGTGNIIY---------PQGASSL---YVPQEAK----FPSVSLKQLVALPRdegdFNDLAVAA 484
Cdd:COG1129 288 GAGRTELARALFGADPADSGEIRLdgkpvrirsPRDAIRAgiaYVPEDRKgeglVLDLSIRENITLAS----LDRLSRGG 363
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 974659840 485 VLHEAGL----GEFIERMK------DADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEAT 539
Cdd:COG1129 364 LLDRRREralaEEYIKRLRiktpspEQPVGN------LSGGNQQKVVLAKWLATDPKVLILDEPT 422
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
409-543 |
1.21e-05 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 46.34 E-value: 1.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 409 RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQG-----------ASSLYVPQEAKFPSV--SLKQLVALPRDEG 475
Cdd:PRK13538 25 NAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLW-QGepirrqrdeyhQDLLYLGHQPGIKTEltALENLRFYQRLHG 103
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 476 DFNDLAVAAVLHEAGLGEFiermKDADAGnspwdmVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK13538 104 PGDDEALWEALAQVGLAGF----EDVPVR------QLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
408-556 |
1.27e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 48.57 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 408 MRAGDWIYMRGESGSGKTSFIKAL-----------------NGLwpygTGNIIYPQ-GASSLYVPQ-EAKFPSVSLKQ-- 466
Cdd:TIGR00956 84 IKPGELTVVLGRPGSGCSTLLKTIasntdgfhigvegvityDGI----TPEEIKKHyRGDVVYNAEtDVHFPHLTVGEtl 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 467 -LVALPR---------DEGDFNDLAVAAVLHEAGLgefiERMKDADAGNspwDMV--LSGGQKQKVMLARILLHKPSIIF 534
Cdd:TIGR00956 160 dFAARCKtpqnrpdgvSREEYAKHIADVYMATYGL----SHTRNTKVGN---DFVrgVSGGERKRVSIAEASLGGAKIQC 232
|
170 180
....*....|....*....|..
gi 974659840 535 LDEATGALDPASKLRFHTALKT 556
Cdd:TIGR00956 233 WDNATRGLDSATALEFIRALKT 254
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
512-556 |
1.31e-05 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 47.39 E-value: 1.31e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKT 556
Cdd:COG4586 155 LSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKE 199
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
398-555 |
1.38e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 47.05 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 398 TPFLRSGVINM----RAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI------------------IYPQGASSLYVPQ 455
Cdd:PRK13649 16 TPFEGRALFDVnltiEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVrvddtlitstsknkdikqIRKKVGLVFQFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 456 EAKFPSVSLKQLVALPRDEGDFNDLAVAAV---LHEAGLGE-FIERmkdadagnSPWDmvLSGGQKQKVMLARILLHKPS 531
Cdd:PRK13649 96 SQLFEETVLKDVAFGPQNFGVSQEEAEALArekLALVGISEsLFEK--------NPFE--LSGGQMRRVAIAGILAMEPK 165
|
170 180
....*....|....*....|....
gi 974659840 532 IIFLDEATGALDPASKLRFHTALK 555
Cdd:PRK13649 166 ILVLDEPTAGLDPKGRKELMTLFK 189
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
383-543 |
1.58e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 48.43 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGaSSLYVPQEAKFPSV 462
Cdd:PLN03232 615 ISIKNGYFSWDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSSVVIRG-SVAYVPQVSWIFNA 693
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQLVALPRD---EGDFNDLAVAAVLHEAGLGEFIERMKDADAGnspwdMVLSGGQKQKVMLARILLHKPSIIFLDEAT 539
Cdd:PLN03232 694 TVRENILFGSDfesERYWRAIDVTALQHDLDLLPGRDLTEIGERG-----VNISGGQKQRVSMARAVYSNSDIYIFDDPL 768
|
....
gi 974659840 540 GALD 543
Cdd:PLN03232 769 SALD 772
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
418-547 |
2.38e-05 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 47.37 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAKF--PSVSLKQLVALPRDEGDfnDLAVAAVLheaglgefi 495
Cdd:COG0488 348 GPNGAGKSTLLKLLAGELEPDSGTVKLGETVKIGYFDQHQEEldPDKTVLDELRDGAPGGT--EQEVRGYL--------- 416
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 496 ERM----KDAD--AGnspwdmVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:COG0488 417 GRFlfsgDDAFkpVG------VLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETL 468
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
406-542 |
2.38e-05 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 47.13 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGT--GNIIY---PQGASSLYVPQEAKFpsVSLKQLVALPRD----EGD 476
Cdd:TIGR02633 22 LEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWsgsPLKASNIRDTERAGI--VIIHQELTLVPElsvaENI 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 974659840 477 F--NDL-------AVAAVLHEAglGEFIERMKDADAGNSPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGAL 542
Cdd:TIGR02633 100 FlgNEItlpggrmAYNAMYLRA--KNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEPSSSL 172
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
418-543 |
2.64e-05 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 46.19 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWP-YGT-----GNIIY------------PQGASSLYVPQEAKFPSVSLKQLVALP------RD 473
Cdd:PRK14246 43 GPSGSGKSTLLKVLNRLIEiYDSkikvdGKVLYfgkdifqidaikLRKEVGMVFQQPNPFPHLSIYDNIAYPlkshgiKE 122
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 474 EGDFNDLaVAAVLHEAGL-GEFIERMkdadagNSPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK14246 123 KREIKKI-VEECLRKVGLwKEVYDRL------NSPASQ-LSGGQQQRLTIARALALKPKVLLMDEPTSMID 185
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
403-569 |
2.80e-05 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 47.18 E-value: 2.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 403 SGVINMRA-GDWIYMRGESGSGKTSFIKALNG-LWPYG-TGNIIYPQGASSLYVPQEAKF--------PSVSLKQ----- 466
Cdd:PLN03211 85 NGVTGMASpGEILAVLGPSGSGKSTLLNALAGrIQGNNfTGTILANNRKPTKQILKRTGFvtqddilyPHLTVREtlvfc 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 467 -LVALPRDEGDFNDLAVA-AVLHEAGLgefiERMKDADAGNSpWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:PLN03211 165 sLLRLPKSLTKQEKILVAeSVISELGL----TKCENTIIGNS-FIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDA 239
|
170 180
....*....|....*....|....*.
gi 974659840 545 ASKLRFHTALKTRCPDA-IVVSIMHE 569
Cdd:PLN03211 240 TAAYRLVLTLGSLAQKGkTIVTSMHQ 265
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
421-539 |
3.27e-05 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 45.74 E-value: 3.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 421 GSGKTSFIKALNGLWPYGTGNIIYpQGA--SSL-----------YVPQEAK-FPSVSLK---QLVALPRDEGDfndlAVA 483
Cdd:COG0410 39 GAGKTTLLKAISGLLPPRSGSIRF-DGEdiTGLpphriarlgigYVPEGRRiFPSLTVEenlLLGAYARRDRA----EVR 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 484 AVLHEAgLGEF--IERMKDADAGNspwdmvLSGGQKQkvMLA--RILLHKPSIIFLDEAT 539
Cdd:COG0410 114 ADLERV-YELFprLKERRRQRAGT------LSGGEQQ--MLAigRALMSRPKLLLLDEPS 164
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
421-547 |
3.64e-05 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 46.46 E-value: 3.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 421 GSGKTSFIKALNGLWPyG--TGNIIY---------PQGASSL---YVPQEAK----FPSVSLKQLVALPrdegDFNDLAV 482
Cdd:PRK13549 298 GAGRTELVQCLFGAYP-GrwEGEIFIdgkpvkirnPQQAIAQgiaMVPEDRKrdgiVPVMGVGKNITLA----ALDRFTG 372
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 483 AAVLHEAG----LGEFIERMKDADAgnSPWDMV--LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:PRK13549 373 GSRIDDAAelktILESIQRLKVKTA--SPELAIarLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAK 441
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
395-547 |
3.88e-05 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 45.48 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 395 ASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYVPQEAKFPSVSLkqLVALPRDE 474
Cdd:PRK10247 17 AGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLF-EGEDISTLKPEIYRQQVSY--CAQTPTLF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 475 GD--FNDL--------------AVAAVLHEAGLGEFIERMKDADagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEA 538
Cdd:PRK10247 94 GDtvYDNLifpwqirnqqpdpaIFLDDLERFALPDTILTKNIAE---------LSGGEKQRISLIRNLQFMPKVLLLDEI 164
|
....*....
gi 974659840 539 TGALDPASK 547
Cdd:PRK10247 165 TSALDESNK 173
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
418-545 |
4.17e-05 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 46.55 E-value: 4.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIY---------PQGASSL---YVPQE-AKFPSVSlkqlVA-------LPRDEG-- 475
Cdd:COG1129 37 GENGAGKSTLMKILSGVYQPDSGEILLdgepvrfrsPRDAQAAgiaIIHQElNLVPNLS----VAeniflgrEPRRGGli 112
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 476 DFNDL--AVAAVLHEAGLGEfiermkdadagnSPWDMV--LSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:COG1129 113 DWRAMrrRARELLARLGLDI------------DPDTPVgdLSVAQQQLVEIARALSRDARVLILDEPTASLTER 174
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
383-543 |
4.58e-05 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 46.86 E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPqgASSLYVPQEAKFPSV 462
Cdd:TIGR00957 637 ITVHNATFTWA-RDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMK--GSVAYVPQQAWIQND 713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQ--LVALPRDEGDFNdlavaAVLHEAGLGEFIERMKDADAGNSPWDMV-LSGGQKQKVMLARILLHKPSIIFLDEAT 539
Cdd:TIGR00957 714 SLREniLFGKALNEKYYQ-----QVLEACALLPDLEILPSGDRTEIGEKGVnLSGGQKQRVSLARAVYSNADIYLFDDPL 788
|
....
gi 974659840 540 GALD 543
Cdd:TIGR00957 789 SAVD 792
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
407-543 |
5.76e-05 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 45.49 E-value: 5.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 407 NMRAGDWIYMRGESGSGKTSFIKALNGLWpygtgniiypqgASSLYVPQEAKFPSvslKQLVALPRDEGD---------- 476
Cdd:PRK09473 38 SLRAGETLGIVGESGSGKSQTAFALMGLL------------AANGRIGGSATFNG---REILNLPEKELNklraeqismi 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 477 FND--------------LAVAAVLHEaGLGE---FIERMKDADAGNSP--------WDMVLSGGQKQKVMLARILLHKPS 531
Cdd:PRK09473 103 FQDpmtslnpymrvgeqLMEVLMLHK-GMSKaeaFEESVRMLDAVKMPearkrmkmYPHEFSGGMRQRVMIAMALLCRPK 181
|
170
....*....|..
gi 974659840 532 IIFLDEATGALD 543
Cdd:PRK09473 182 LLIADEPTTALD 193
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
418-575 |
6.34e-05 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 45.93 E-value: 6.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSLYVPQEAkfpsvsLKQLVAL----PRDEGDF------NDLAVAAVLH 487
Cdd:PRK09700 296 GLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDA------VKKGMAYitesRRDNGFFpnfsiaQNMAISRSLK 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 488 EAGL----GEFIERMKDADAGNSPWDMV------------LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFH 551
Cdd:PRK09700 370 DGGYkgamGLFHEVDEQRTAENQRELLAlkchsvnqniteLSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIY 449
|
170 180
....*....|....*....|....
gi 974659840 552 TALKTRCPDAIVVsIMHEEKLPTL 575
Cdd:PRK09700 450 KVMRQLADDGKVI-LMVSSELPEI 472
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
512-544 |
7.01e-05 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 44.79 E-value: 7.01e-05
10 20 30
....*....|....*....|....*....|...
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG4598 155 LSGGQQQRAAIARALAMEPEVMLFDEPTSALDP 187
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
414-573 |
7.18e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 43.13 E-value: 7.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 414 IYMRGESGSGKTSFIKALnglwpygtGNIIYPQGASSLYVpqeakfpsvslkqlvalprdEGDFNDLAVAAVLHEAGLGE 493
Cdd:smart00382 5 ILIVGPPGSGKTTLARAL--------ARELGPPGGGVIYI--------------------DGEDILEEVLDQLLLIIVGG 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 494 FiermkdadagnspwDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK-------LRFHTALKTRCPDAIVVSI 566
Cdd:smart00382 57 K--------------KASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEallllleELRLLLLLKSEKNLTVILT 122
|
....*..
gi 974659840 567 MHEEKLP 573
Cdd:smart00382 123 TNDEKDL 129
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
512-581 |
7.31e-05 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 45.21 E-value: 7.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS------KLRfhtALKTRCPDAIVVS-IMHE-----EKLPTLESGE 579
Cdd:PRK13536 173 LSGGMKRRLTLARALINDPQLLILDEPTTGLDPHArhliweRLR---SLLARGKTILLTThFMEEaerlcDRLCVLEAGR 249
|
..
gi 974659840 580 SI 581
Cdd:PRK13536 250 KI 251
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
475-576 |
9.71e-05 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 44.46 E-value: 9.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 475 GDFNDLAVAAVLHEAGLGEFIERMKD------ADAGnspwdMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKL 548
Cdd:cd03289 101 GKWSDEEIWKVAEEVGLKSVIEQFPGqldfvlVDGG-----CVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQ 175
|
90 100
....*....|....*....|....*....
gi 974659840 549 RFHTALKTRCPDAIVvsIMHEEKL-PTLE 576
Cdd:cd03289 176 VIRKTLKQAFADCTV--ILSEHRIeAMLE 202
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
396-595 |
1.09e-04 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 45.04 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 396 SETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNI---------IYPQGASSL--Y-VPQEAK-FPSV 462
Cdd:PRK15439 22 SGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLeiggnpcarLTPAKAHQLgiYlVPQEPLlFPNL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 463 SLKQ--LVALPRDEGDFNDLAvaAVLHEagLGEFIErmKDADAGnspwdmVLSGGQKQKVMLARILLHKPSIIFLDEATG 540
Cdd:PRK15439 102 SVKEniLFGLPKRQASMQKMK--QLLAA--LGCQLD--LDSSAG------SLEVADRQIVEILRGLMRDSRILILDEPTA 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 541 ALDPASKLRFHTALKT-RCPDAIVVSIMHeeKLPTLesgESIFSHVLDIANGYVSL 595
Cdd:PRK15439 170 SLTPAETERLFSRIRElLAQGVGIVFISH--KLPEI---RQLADRISVMRDGTIAL 220
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
512-549 |
1.20e-04 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 44.68 E-value: 1.20e-04
10 20 30
....*....|....*....|....*....|....*...
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPasKLR 549
Cdd:COG3839 134 LSGGQRQRVALGRALVREPKVFLLDEPLSNLDA--KLR 169
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
512-546 |
1.21e-04 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 44.23 E-value: 1.21e-04
10 20 30
....*....|....*....|....*....|....*
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:PRK09984 153 LSGGQQQRVAIARALMQQAKVILADEPIASLDPES 187
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
403-546 |
1.22e-04 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 45.04 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 403 SGVInmRAGDWIYMRGESGSGKTSFIKALNGLWPYGT---GNII---YPQGAS-----SLYVPQEAKF-PSVSLKQ---- 466
Cdd:TIGR00955 45 SGVA--KPGELLAVMGSSGAGKTTLMNALAFRSPKGVkgsGSVLlngMPIDAKemraiSAYVQQDDLFiPTLTVREhlmf 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 467 --LVALPRDEG-DFNDLAVAAVLHEAGLGefiermkdaDAGN----SPWDM-VLSGGQKQKVMLARILLHKPSIIFLDEA 538
Cdd:TIGR00955 123 qaHLRMPRRVTkKEKRERVDEVLQALGLR---------KCANtrigVPGRVkGLSGGERKRLAFASELLTDPPLLFCDEP 193
|
....*...
gi 974659840 539 TGALDPAS 546
Cdd:TIGR00955 194 TSGLDSFM 201
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
418-554 |
1.38e-04 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 43.18 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQGA------SSL--------YVPQEA--KFPSVSLKQLVAL-PRDEGdFNDL 480
Cdd:TIGR01166 25 GANGAGKSTLLLHLNGLLRPQSGAVLI-DGEpldysrKGLlerrqrvgLVFQDPddQLFAADVDQDVAFgPLNLG-LSEA 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 481 AVAAVLHEA----GLGEFIERmkdadagnsPWDMvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTAL 554
Cdd:TIGR01166 103 EVERRVREAltavGASGLRER---------PTHC-LSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDPAGREQMLAIL 170
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
396-543 |
1.42e-04 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 44.94 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 396 SETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQ----------------GASSLYVPQEAKF 459
Cdd:PRK11147 14 SDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQdlivarlqqdpprnveGTVYDFVAEGIEE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 460 PSVSLKQ------LVALPRDEGDFNDLA-VAAVLHEAGLGEFIERMK--------DADAGNSPwdmvLSGGQKQKVMLAR 524
Cdd:PRK11147 94 QAEYLKRyhdishLVETDPSEKNLNELAkLQEQLDHHNLWQLENRINevlaqlglDPDAALSS----LSGGWLRKAALGR 169
|
170
....*....|....*....
gi 974659840 525 ILLHKPSIIFLDEATGALD 543
Cdd:PRK11147 170 ALVSNPDVLLLDEPTNHLD 188
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
477-568 |
1.48e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 44.90 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 477 FNDLAVAAVLHEAGLGEFIERMKD------ADAGnspwdMVLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRF 550
Cdd:TIGR01271 1318 WSDEEIWKVAEEVGLKSVIEQFPDkldfvlVDGG-----YVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQII 1392
|
90
....*....|....*...
gi 974659840 551 HTALKTRCPDAIVVSIMH 568
Cdd:TIGR01271 1393 RKTLKQSFSNCTVILSEH 1410
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
462-543 |
1.66e-04 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 44.70 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 VSLKQLVALPRDEgdfndlAVAAVLHEAGLgefiermkDADAgNSPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGA 541
Cdd:PRK15134 391 VHQPTLSAAQREQ------QVIAVMEEVGL--------DPET-RHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSS 455
|
..
gi 974659840 542 LD 543
Cdd:PRK15134 456 LD 457
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
418-547 |
1.67e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 43.96 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGlwpygtgniIYPQGASSLYVPQEAKFPSVS--LKQLVAL----PRDE----GDFNDLAVAAVLH 487
Cdd:PRK13647 38 GPNGAGKSTLLLHLNG---------IYLPQRGRVKVMGREVNAENEkwVRSKVGLvfqdPDDQvfssTVWDDVAFGPVNM 108
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 488 EAGLGEFIERMKDADAGNSPWDMV------LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:PRK13647 109 GLDKDEVERRVEEALKAVRMWDFRdkppyhLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQ 174
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
383-543 |
1.75e-04 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 44.29 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTL-MQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTsfIKALN--GLWPYG----TGNIIYpQGASSLYVP- 454
Cdd:COG4172 7 LSVEDLSVaFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKS--VTALSilRLLPDPaahpSGSILF-DGQDLLGLSe 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 455 ---------------QEakfPSVSL-------KQLV-------ALPRDEgdfndlA---VAAVLHEAGLGEFIERMKDad 502
Cdd:COG4172 84 relrrirgnriamifQE---PMTSLnplhtigKQIAevlrlhrGLSGAA------ArarALELLERVGIPDPERRLDA-- 152
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 974659840 503 agnspWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:COG4172 153 -----YPHQLSGGQRQRVMIAMALANEPDLLIADEPTTALD 188
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
482-575 |
1.87e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 43.64 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 482 VAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDP---ASKLRFHTALKTRC 558
Cdd:PRK13652 118 VSSALHMLGLEELRDRVPHH----------LSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPqgvKELIDFLNDLPETY 187
|
90
....*....|....*..
gi 974659840 559 PDAIVVSIMHEEKLPTL 575
Cdd:PRK13652 188 GMTVIFSTHQLDLVPEM 204
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
383-543 |
2.30e-04 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 43.38 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGPasetpflRSGVIN----MRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQGASSL------- 451
Cdd:PRK11701 7 LSVRGLTKLYGP-------RKGCRDvsfdLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGQLrdlyals 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 -------------YVPQEAK---FPSVSL-----KQLVAL-PRDEGDFNDLAvAAVLHEAGLGEfiERMKDADAgnspwd 509
Cdd:PRK11701 80 eaerrrllrtewgFVHQHPRdglRMQVSAggnigERLMAVgARHYGDIRATA-GDWLERVEIDA--ARIDDLPT------ 150
|
170 180 190
....*....|....*....|....*....|....
gi 974659840 510 mVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11701 151 -TFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLD 183
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
512-546 |
2.49e-04 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 43.15 E-value: 2.49e-04
10 20 30
....*....|....*....|....*....|....*
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:COG1101 149 LSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKT 183
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
418-543 |
3.01e-04 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 42.85 E-value: 3.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASSL----YVPQEAKF----PSVSLK------QLVALPRD-----EGDFN 478
Cdd:PRK15112 46 GENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFgdysYRSQRIRMifqdPSTSLNprqrisQILDFPLRlntdlEPEQR 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 974659840 479 DLAVAAVLHEAGLgefierMKDaDAGNSPwdMVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK15112 126 EKQIIETLRQVGL------LPD-HASYYP--HMLAPGQKQRLGLARALILRPKVIIADEALASLD 181
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
512-546 |
3.24e-04 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 43.56 E-value: 3.24e-04
10 20 30
....*....|....*....|....*....|....*
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:PRK10535 145 LSGGQQQRVSIARALMNGGQVILADEPTGALDSHS 179
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
512-568 |
3.26e-04 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 42.97 E-value: 3.26e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASKLRFHTALKTRCPDAIVVSIMH 568
Cdd:cd03288 157 FSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAH 213
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
406-544 |
4.22e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 42.53 E-value: 4.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 406 INMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYvpqeAKFPSVSLKQLVALPRDEGDfNDLAVAAV 485
Cdd:PRK13636 27 INIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILF-DGKPIDY----SRKGLMKLRESVGMVFQDPD-NQLFSASV 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 486 LHEAGLG---------EFIERMKDADA--GNSPWD----MVLSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:PRK13636 101 YQDVSFGavnlklpedEVRKRVDNALKrtGIEHLKdkptHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDP 174
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
452-544 |
4.41e-04 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 42.32 E-value: 4.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 YVPQEakfPSVslkqlvalprdegdFNDLAVA----AVLH-------------EAGLGEF-IERMKDADAgnspwdMVLS 513
Cdd:COG1137 82 YLPQE---ASI--------------FRKLTVEdnilAVLElrklskkereerlEELLEEFgITHLRKSKA------YSLS 138
|
90 100 110
....*....|....*....|....*....|.
gi 974659840 514 GGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG1137 139 GGERRRVEIARALATNPKFILLDEPFAGVDP 169
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
408-547 |
5.18e-04 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 42.49 E-value: 5.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 408 MRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY-----PQGASSL-----YVPQEAKF-PSVSLKQ-LVALPRDEG 475
Cdd:PRK13537 30 VQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLcgepvPSRARHArqrvgVVPQFDNLdPDFTVREnLLVFGRYFG 109
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 476 DFNDLAVAAVlheAGLGEF--IERMKDADAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:PRK13537 110 LSAAAARALV---PPLLEFakLENKADAKVGE------LSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQAR 174
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
360-582 |
6.64e-04 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 42.15 E-value: 6.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 360 PAEFYARSGVNRFAFTHQHPRFGLSVRNLTLMQgpaseTPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGT 439
Cdd:cd03291 17 FGELLEKAKQENNDRKHSSDDNNLFFSNLCLVG-----APVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 440 GNIIYPQGASslYVPQEAKFPSVSLKQ--LVALPRDEGDFNDLAVAAVLHEaGLGEFIERMKD--ADAGnspwdMVLSGG 515
Cdd:cd03291 92 GKIKHSGRIS--FSSQFSWIMPGTIKEniIFGVSYDEYRYKSVVKACQLEE-DITKFPEKDNTvlGEGG-----ITLSGG 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 516 QKQKVMLARILLHKPSIIFLDEATGALDPAS-KLRFHTAL------KTRCpdaIVVSIMHE----EKLPTLESGESIF 582
Cdd:cd03291 164 QRARISLARAVYKDADLYLLDSPFGYLDVFTeKEIFESCVcklmanKTRI---LVTSKMEHlkkaDKILILHEGSSYF 238
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
418-547 |
7.38e-04 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 41.92 E-value: 7.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYpQGASSLYvpqeAKFPSVSLKQLVAL----PRDEGDFNDLA--VAAVLHEAGL 491
Cdd:PRK13638 34 GANGCGKSTLFMNLSGLLRPQKGAVLW-QGKPLDY----SKRGLLALRQQVATvfqdPEQQIFYTDIDsdIAFSLRNLGV 108
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 492 GE--FIERMKDA----DAGNSPWDMV--LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:PRK13638 109 PEaeITRRVDEAltlvDAQHFRHQPIqcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGR 172
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
512-547 |
8.35e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 42.41 E-value: 8.35e-04
10 20 30
....*....|....*....|....*....|....*.
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAK 427
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
512-543 |
8.64e-04 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 42.03 E-value: 8.64e-04
10 20 30
....*....|....*....|....*....|..
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:COG4608 158 FSGGQRQRIGIARALALNPKLIVCDEPVSALD 189
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
418-545 |
9.29e-04 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 41.05 E-value: 9.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNII------------YPQGASSLYVPqeAKFPSVS-LKQLVALPRDEGdFNDLAVAA 484
Cdd:cd03268 33 GPNGAGKTTTMKIILGLIKPDSGEITfdgksyqknieaLRRIGALIEAP--GFYPNLTaRENLRLLARLLG-IRKKRIDE 109
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 974659840 485 VLHEAGLGEfIERMKDADagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:cd03268 110 VLDVVGLKD-SAKKKVKG---------FSLGMKQRLGIALALLGNPDLLILDEPTNGLDPD 160
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
512-543 |
9.77e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 42.15 E-value: 9.77e-04
10 20 30
....*....|....*....|....*....|..
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PLN03073 628 LSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
383-543 |
1.08e-03 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 41.15 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTLMQGpasETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIY---PQGASS--------L 451
Cdd:PRK11231 3 LRTENLTVGYG---TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLgdkPISMLSsrqlarrlA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 YVPQEAKFPS-VSLKQLVALPRDE--------GDFNDLAVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVML 522
Cdd:PRK11231 80 LLPQHHLTPEgITVRELVAYGRSPwlslwgrlSAEDNARVNQAMEQTRINHLADRRLTD----------LSGGQRQRAFL 149
|
170 180
....*....|....*....|.
gi 974659840 523 ARILLHKPSIIFLDEATGALD 543
Cdd:PRK11231 150 AMVLAQDTPVVLLDEPTTYLD 170
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
418-543 |
1.09e-03 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 41.63 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYP---------QGASSLYVPQE-AKFPSVSLKQLVA-------LPRDEgdfNDL 480
Cdd:PRK11432 39 GPSGCGKTTVLRLVAGLEKPTEGQIFIDgedvthrsiQQRDICMVFQSyALFPHMSLGENVGyglkmlgVPKEE---RKQ 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 974659840 481 AVAAVLHEAGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11432 116 RVKEALELVDLAGFEDRYVDQ----------ISGGQQQRVALARALILKPKVLLFDEPLSNLD 168
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
475-571 |
1.32e-03 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 40.25 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 475 GDFNDLAVAAVLHEAGLGE--FIERMK---DADAGNSPWDMV----------LSGGQKQKVMLARILLHKPSIIFLDEAT 539
Cdd:cd03222 20 GVVKEGEVIGIVGPNGTGKttAVKILAgqlIPNGDNDEWDGItpvykpqyidLSGGELQRVAIAAALLRNATFYLFDEPS 99
|
90 100 110
....*....|....*....|....*....|..
gi 974659840 540 GALDpaSKLRFHTAlktrcpDAIVVSIMHEEK 571
Cdd:cd03222 100 AYLD--IEQRLNAA------RAIRRLSEEGKK 123
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
512-543 |
1.51e-03 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 40.83 E-value: 1.51e-03
10 20 30
....*....|....*....|....*....|..
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK10419 152 LSGGQLQRVCLARALAVEPKLLILDEAVSNLD 183
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
382-550 |
1.75e-03 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 40.45 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 382 GLSVRNLTLmqgpASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGT----------GNIIYPQG---- 447
Cdd:PRK10418 4 QIELRNIAL----QAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGVrqtagrvlldGKPVAPCAlrgr 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 448 --ASSLYVPQEAKFP-----SVSLKQLVALPRDEgdfNDLAVAAVLHEAGLGEfIERMKDAdagnSPWDMvlSGGQKQKV 520
Cdd:PRK10418 80 kiATIMQNPRSAFNPlhtmhTHARETCLALGKPA---DDATLTAALEAVGLEN-AARVLKL----YPFEM--SGGMLQRM 149
|
170 180 190
....*....|....*....|....*....|
gi 974659840 521 MLARILLHKPSIIFLDEATGALDPASKLRF 550
Cdd:PRK10418 150 MIALALLCEAPFIIADEPTTDLDVVAQARI 179
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
513-543 |
1.81e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 40.72 E-value: 1.81e-03
10 20 30
....*....|....*....|....*....|.
gi 974659840 513 SGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK11308 156 SGGQRQRIAIARALMLDPDVVVADEPVSALD 186
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
512-544 |
2.07e-03 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 40.48 E-value: 2.07e-03
10 20 30
....*....|....*....|....*....|...
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:COG4152 130 LSKGNQQKVQLIAALLHDPELLILDEPFSGLDP 162
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
401-544 |
2.37e-03 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 40.79 E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 401 LRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpqGASSLYVPQEAKFPSVSLKQLVALPRDegdFNDL 480
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLI--DGVDIAKISDAELREVRRKKIAMVFQS---FALM 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 974659840 481 AVAAVLHEAGLGEFIERMKDADAGNSPWDMV---------------LSGGQKQKVMLARILLHKPSIIFLDEATGALDP 544
Cdd:PRK10070 119 PHMTVLDNTAFGMELAGINAEERREKALDALrqvglenyahsypdeLSGGMRQRVGLARALAINPDILLMDEAFSALDP 197
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
421-545 |
2.45e-03 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 39.73 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 421 GSGKTSFIKALNGLWPYGTGNIIYpQGA--SSLYVPQEAK------------FPSVSLKQ--LVALPRDEGDFNDLA--- 481
Cdd:cd03219 36 GAGKTTLFNLISGFLRPTSGSVLF-DGEdiTGLPPHEIARlgigrtfqiprlFPELTVLEnvMVAAQARTGSGLLLArar 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 974659840 482 ---------VAAVLHEAGLGEFIERMkdadAGNspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:cd03219 115 reerearerAEELLERVGLADLADRP----AGE------LSYGQQRRLEIARALATDPKLLLLDEPAAGLNPE 177
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
452-546 |
2.83e-03 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 39.83 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 452 YVPQEAkfpSVslkqlvalprdegdFNDLAVA----AVLHEAG-------------LGEF-IERMKDADAgnspwdMVLS 513
Cdd:cd03218 79 YLPQEA---SI--------------FRKLTVEenilAVLEIRGlskkereekleelLEEFhITHLRKSKA------SSLS 135
|
90 100 110
....*....|....*....|....*....|...
gi 974659840 514 GGQKQKVMLARILLHKPSIIFLDEATGALDPAS 546
Cdd:cd03218 136 GGERRRVEIARALATNPKFLLLDEPFAGVDPIA 168
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
512-543 |
3.39e-03 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 39.24 E-value: 3.39e-03
10 20 30
....*....|....*....|....*....|..
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:cd03290 141 LSGGQRQRICVARALYQNTNIVFLDDPFSALD 172
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
487-543 |
3.48e-03 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 40.73 E-value: 3.48e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 974659840 487 HEAGLGEFIERMKDADA-GNSPWDM---VLSGG------QKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PLN03232 1337 NDADLWEALERAHIKDViDRNPFGLdaeVSEGGenfsvgQRQLLSLARALLRRSKILVLDEATASVD 1403
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
418-545 |
3.75e-03 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 39.39 E-value: 3.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 418 GESGSGKTSFIKALNGLWPYGTGNIIYPQGASS-----------LYVPQEakFPS---VSLKQLVALPRDE-----GDFN 478
Cdd:PRK10575 44 GHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswsskafarkvAYLPQQ--LPAaegMTVRELVAIGRYPwhgalGRFG 121
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 974659840 479 -------DLAVAAVlheaGLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPA 545
Cdd:PRK10575 122 aadrekvEEAISLV----GLKPLAHRLVDS----------LSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIA 181
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
482-549 |
3.80e-03 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 40.01 E-value: 3.80e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 974659840 482 VAAVLHeagLGEFIERMKDAdagnspwdmvLSGGQKQKVMLARILLHKPSIIFLDEATGALDPAskLR 549
Cdd:PRK11000 117 VAEVLQ---LAHLLDRKPKA----------LSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAA--LR 169
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
512-547 |
3.88e-03 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 39.99 E-value: 3.88e-03
10 20 30
....*....|....*....|....*....|....*.
gi 974659840 512 LSGGQKQKVMLARILLHKPSIIFLDEATGALDPASK 547
Cdd:PRK10762 396 LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAK 431
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
394-543 |
5.38e-03 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 39.70 E-value: 5.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 394 PASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYpQGA-----------SSLYVPQEAKFP-S 461
Cdd:PRK10789 324 PQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRF-HDIpltklqldswrSRLAVVSQTPFLfS 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 462 VSLKQLVALPRDEGDFNDLAVAAVLheAGLGEFIERMK---DADAGNSpwDMVLSGGQKQKVMLARILLHKPSIIFLDEA 538
Cdd:PRK10789 403 DTVANNIALGRPDATQQEIEHVARL--ASVHDDILRLPqgyDTEVGER--GVMLSGGQKQRISIARALLLNAEILILDDA 478
|
....*
gi 974659840 539 TGALD 543
Cdd:PRK10789 479 LSAVD 483
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
512-543 |
5.71e-03 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 39.55 E-value: 5.71e-03
10 20 30
....*....|....*....|....*....|...
gi 974659840 512 LSGGQKQKVMLARILLhKPS-IIFLDEATGALD 543
Cdd:PRK11147 441 LSGGERNRLLLARLFL-KPSnLLILDEPTNDLD 472
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
512-572 |
7.33e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 37.72 E-value: 7.33e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 974659840 512 LSGGQKQKVMLARIL---LHKP-SIIFLDEATGALDPASKLRFHTALK-TRCPDAIVVSIMHEEKL 572
Cdd:cd03227 78 LSGGEKELSALALILalaSLKPrPLYILDEIDRGLDPRDGQALAEAILeHLVKGAQVIVITHLPEL 143
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
383-543 |
9.63e-03 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 39.07 E-value: 9.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 383 LSVRNLTL-MQGPASETPFLRSGVINMRAGDWIYMRGESGSGKTSFIKALNGLWPYGTGNIIYPQ--------------- 446
Cdd:PRK10261 13 LAVENLNIaFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKmllrrrsrqvielse 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 974659840 447 ----------GASSLYVPQEakfPSVSLKQLVALPRDegdfndLAVAAVLHEaGLG---EFIE--------RMKDADAGN 505
Cdd:PRK10261 93 qsaaqmrhvrGADMAMIFQE---PMTSLNPVFTVGEQ------IAESIRLHQ-GASreeAMVEakrmldqvRIPEAQTIL 162
|
170 180 190
....*....|....*....|....*....|....*...
gi 974659840 506 SPWDMVLSGGQKQKVMLARILLHKPSIIFLDEATGALD 543
Cdd:PRK10261 163 SRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALD 200
|
|
| |
