NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|981351934|ref|WP_059567520|]
View 

Fe-S cluster assembly protein IscX [Burkholderia stagnalis]

Protein Classification

Fe-S cluster assembly protein IscX( domain architecture ID 10516386)

Fe-S cluster assembly protein IscX may function as iron donor in the assembly of iron-sulfur clusters

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
IscX COG2975
Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, ...
 1-64 6.54e-37

Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 442214  Cd Length: 64  Bit Score: 117.59  E-value: 6.54e-37
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934  1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:COG2975   1 MKWTDTEDIAIALYEKHPDVDPLTVRFTDLHRWVLELPGFDDDPERSNEKILEAIQMAWIEEAE 64
 
Name Accession Description Interval E-value
IscX COG2975
Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, ...
 1-64 6.54e-37

Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442214  Cd Length: 64  Bit Score: 117.59  E-value: 6.54e-37
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934  1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:COG2975   1 MKWTDTEDIAIALYEKHPDVDPLTVRFTDLHRWVLELPGFDDDPERSNEKILEAIQMAWIEEAE 64
Fe-S_assembly pfam04384
Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the ...
 1-64 1.40e-35

Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the assembly of iron-sulphur clusters. It may function as an adaptor protein. In Escherichia coli Swiss:P0C0L9 forms part of the isc operon, which encodes genes involved in iron-sulphur cluster assembly. Its structure is entirely alpha helical, and it contains a modified wing-helix structure, usually found in DNA-binding proteins. It binds to Fe2+ and Fe3+ ions and to the cysteine desulfurase IscS, the same surface of the protein is involved in both binding to iron and to IscS.


Pssm-ID: 427912  Cd Length: 64  Bit Score: 114.15  E-value: 1.40e-35
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934   1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:pfam04384  1 MKWTDTEDIAIALYEKYPDVDPLTVRFTDLHEWVLELPGFDDDPEKSNEKILEAIQMAWIEERE 64
iscX_yfhJ TIGR03412
FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC ...
 2-64 1.78e-33

FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC system for iron-sulfur cluster assembly. Other genes in the system include iscSUA, hscBA, and fdx. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 132453  Cd Length: 63  Bit Score: 108.91  E-value: 1.78e-33
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 981351934   2 KWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:TIGR03412  1 KWTDSQEIAIALAEAHPDVDPKTVRFTDLHQWVLELPGFDDDPKRCNEKILEAIQMAWIDERE 63
PRK10721 PRK10721
hypothetical protein; Provisional
 1-64 2.78e-20

hypothetical protein; Provisional


Pssm-ID: 170660  Cd Length: 66  Bit Score: 75.67  E-value: 2.78e-20
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934  1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:PRK10721  3 LKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICELEDFDDDPQASNEKILEAILLVWLDEAE 66
 
Name Accession Description Interval E-value
IscX COG2975
Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, ...
 1-64 6.54e-37

Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442214  Cd Length: 64  Bit Score: 117.59  E-value: 6.54e-37
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934  1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:COG2975   1 MKWTDTEDIAIALYEKHPDVDPLTVRFTDLHRWVLELPGFDDDPERSNEKILEAIQMAWIEEAE 64
Fe-S_assembly pfam04384
Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the ...
 1-64 1.40e-35

Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the assembly of iron-sulphur clusters. It may function as an adaptor protein. In Escherichia coli Swiss:P0C0L9 forms part of the isc operon, which encodes genes involved in iron-sulphur cluster assembly. Its structure is entirely alpha helical, and it contains a modified wing-helix structure, usually found in DNA-binding proteins. It binds to Fe2+ and Fe3+ ions and to the cysteine desulfurase IscS, the same surface of the protein is involved in both binding to iron and to IscS.


Pssm-ID: 427912  Cd Length: 64  Bit Score: 114.15  E-value: 1.40e-35
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934   1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:pfam04384  1 MKWTDTEDIAIALYEKYPDVDPLTVRFTDLHEWVLELPGFDDDPEKSNEKILEAIQMAWIEERE 64
iscX_yfhJ TIGR03412
FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC ...
 2-64 1.78e-33

FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC system for iron-sulfur cluster assembly. Other genes in the system include iscSUA, hscBA, and fdx. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 132453  Cd Length: 63  Bit Score: 108.91  E-value: 1.78e-33
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 981351934   2 KWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:TIGR03412  1 KWTDSQEIAIALAEAHPDVDPKTVRFTDLHQWVLELPGFDDDPKRCNEKILEAIQMAWIDERE 63
PRK10721 PRK10721
hypothetical protein; Provisional
 1-64 2.78e-20

hypothetical protein; Provisional


Pssm-ID: 170660  Cd Length: 66  Bit Score: 75.67  E-value: 2.78e-20
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 981351934  1 MKWTDSREIAIALAEKHPDIDPQRINFVDLRQWVLELDGFSDDPKHSGEKILEAIQAHWIDESD 64
Cdd:PRK10721  3 LKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICELEDFDDDPQASNEKILEAILLVWLDEAE 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH