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Conserved domains on  [gi|981351976|ref|WP_059567562|]
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rhodanese-like domain-containing protein [Burkholderia stagnalis]

Protein Classification

rhodanese-like domain-containing protein( domain architecture ID 10107425)

rhodanese-like domain-containing protein similar to Acidithiobacillus ferrooxidans rhodanese-like protein P15, which is identified as a thiosulfate:cyanide sulfurtransferase (TST)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RHOD_1 cd01522
Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative ...
 26-146 8.51e-47

Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins.


:

Pssm-ID: 238780 [Multi-domain]  Cd Length: 117  Bit Score: 147.86  E-value: 8.51e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  26 LLPAEAFELLQLDPSARLVDVRTRAELDWVGRPlvgdGQYLHLEWTRYPGGVPNAEFVSELKAAIEPGAPVLFLCRSAAR 105
Cdd:cd01522    1 LTPAEAWALLQADPQAVLVDVRTEAEWKFVGGV----PDAVHVAWQVYPDMEINPNFLAELEEKVGKDRPVLLLCRSGNR 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 981351976 106 SKLAAVAAAQAGFTKAFDLLEGFEGAKDAEGHRKTVDGWCF 146
Cdd:cd01522   77 SIAAAEAAAQAGFTNVYNVLEGFEGDLDAAGHRGGVNGWRF 117
 
Name Accession Description Interval E-value
RHOD_1 cd01522
Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative ...
 26-146 8.51e-47

Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins.


Pssm-ID: 238780 [Multi-domain]  Cd Length: 117  Bit Score: 147.86  E-value: 8.51e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  26 LLPAEAFELLQLDPSARLVDVRTRAELDWVGRPlvgdGQYLHLEWTRYPGGVPNAEFVSELKAAIEPGAPVLFLCRSAAR 105
Cdd:cd01522    1 LTPAEAWALLQADPQAVLVDVRTEAEWKFVGGV----PDAVHVAWQVYPDMEINPNFLAELEEKVGKDRPVLLLCRSGNR 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 981351976 106 SKLAAVAAAQAGFTKAFDLLEGFEGAKDAEGHRKTVDGWCF 146
Cdd:cd01522   77 SIAAAEAAAQAGFTNVYNVLEGFEGDLDAAGHRGGVNGWRF 117
PspE COG0607
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; ...
 28-134 7.98e-10

Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Rhodanese-related sulfurtransferase is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440372 [Multi-domain]  Cd Length: 106  Bit Score: 53.05  E-value: 7.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  28 PAEAFELLQlDPSARLVDVRTRAELDWVgrplvgdgqylHLewtryPGGV--PNAEFVSELkAAIEPGAPVLFLCRSAAR 105
Cdd:COG0607    8 PAELAELLE-SEDAVLLDVREPEEFAAG-----------HI-----PGAIniPLGELAERL-DELPKDKPIVVYCASGGR 69

                         90       100
                 ....*....|....*....|....*....
gi 981351976 106 SKLAAVAAAQAGFTKAFDLLEGFEGAKDA 134
Cdd:COG0607   70 SAQAAALLRRAGYTNVYNLAGGIEAWKAA 98
RHOD smart00450
Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The ...
 38-137 6.65e-04

Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The the Cysteine containing enzymatically active version of the domain is also found in the CDC25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and stress proteins such as Senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions with a loss of the cysteine are also seen in Dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases. These are likely to play a role in protein interactions.


Pssm-ID: 197731 [Multi-domain]  Cd Length: 100  Bit Score: 37.05  E-value: 6.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976    38 DPSARLVDVRTRAELDwVGRPLvgDGQYLHLEWTRYPGGV-PNAEFVSELKAA-IEPGAPVLFLCRSAARSKLAAVAAAQ 115
Cdd:smart00450   2 DEKVVLLDVRSPEEYE-GGHIP--GAVNIPLSELLDRRGElDILEFEELLKRLgLDKDKPVVVYCRSGNRSAKAAWLLRE 78

                           90       100
                   ....*....|....*....|..
gi 981351976   116 AGFTKAFDLLEGFEGAKDAEGH 137
Cdd:smart00450  79 LGFKNVYLLDGGYKEWSAAGPP 100
 
Name Accession Description Interval E-value
RHOD_1 cd01522
Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative ...
 26-146 8.51e-47

Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins.


Pssm-ID: 238780 [Multi-domain]  Cd Length: 117  Bit Score: 147.86  E-value: 8.51e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  26 LLPAEAFELLQLDPSARLVDVRTRAELDWVGRPlvgdGQYLHLEWTRYPGGVPNAEFVSELKAAIEPGAPVLFLCRSAAR 105
Cdd:cd01522    1 LTPAEAWALLQADPQAVLVDVRTEAEWKFVGGV----PDAVHVAWQVYPDMEINPNFLAELEEKVGKDRPVLLLCRSGNR 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 981351976 106 SKLAAVAAAQAGFTKAFDLLEGFEGAKDAEGHRKTVDGWCF 146
Cdd:cd01522   77 SIAAAEAAAQAGFTNVYNVLEGFEGDLDAAGHRGGVNGWRF 117
PspE COG0607
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; ...
 28-134 7.98e-10

Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Rhodanese-related sulfurtransferase is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440372 [Multi-domain]  Cd Length: 106  Bit Score: 53.05  E-value: 7.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  28 PAEAFELLQlDPSARLVDVRTRAELDWVgrplvgdgqylHLewtryPGGV--PNAEFVSELkAAIEPGAPVLFLCRSAAR 105
Cdd:COG0607    8 PAELAELLE-SEDAVLLDVREPEEFAAG-----------HI-----PGAIniPLGELAERL-DELPKDKPIVVYCASGGR 69

                         90       100
                 ....*....|....*....|....*....
gi 981351976 106 SKLAAVAAAQAGFTKAFDLLEGFEGAKDA 134
Cdd:COG0607   70 SAQAAALLRRAGYTNVYNLAGGIEAWKAA 98
Polysulfide_ST cd01447
Polysulfide-sulfurtransferase - Rhodanese Homology Domain. This domain is believed to serve as ...
 28-134 2.11e-04

Polysulfide-sulfurtransferase - Rhodanese Homology Domain. This domain is believed to serve as a polysulfide binding and transferase domain in anaerobic gram-negative bacteria, functioning in oxidative phosphorylation with polysulfide-sulfur as a terminal electron acceptor. The active site contains the same conserved cysteine that is the catalytic residue in other Rhodanese Homology Domain proteins.


Pssm-ID: 238724 [Multi-domain]  Cd Length: 103  Bit Score: 38.56  E-value: 2.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  28 PAEAFELLQlDPSARLVDVRTRAELDwvgrplvgdgqylhlewtrYPGGVPNAEFVSE-------------LKAAIEPGA 94
Cdd:cd01447    3 PEDARALLG-SPGVLLVDVRDPRELE-------------------RTGMIPGAFHAPRgmlefwadpdspyHKPAFAEDK 62

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 981351976  95 PVLFLCRSAARSKLAAVAAAQAGFTKAFDLLEGFEGAKDA 134
Cdd:cd01447   63 PFVFYCASGWRSALAGKTLQDMGLKPVYNIEGGFKDWKEA 102
RHOD cd00158
Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese ...
 30-130 2.17e-04

Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.


Pssm-ID: 238089 [Multi-domain]  Cd Length: 89  Bit Score: 38.05  E-value: 2.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976  30 EAFELLQlDPSARLVDVRTRAELDWVgrplvgdgqylHLewtryPGGV--PNAEFVSELK-AAIEPGAPVLFLCRSAARS 106
Cdd:cd00158    1 ELKELLD-DEDAVLLDVREPEEYAAG-----------HI-----PGAIniPLSELEERAAlLELDKDKPIVVYCRSGNRS 63

                         90       100
                 ....*....|....*....|....
gi 981351976 107 KLAAVAAAQAGFTKAFDLLEGFEG 130
Cdd:cd00158   64 ARAAKLLRKAGGTNVYNLEGGMLA 87
RHOD smart00450
Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The ...
 38-137 6.65e-04

Rhodanese Homology Domain; An alpha beta fold found duplicated in the Rhodanese protein. The the Cysteine containing enzymatically active version of the domain is also found in the CDC25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and stress proteins such as Senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions with a loss of the cysteine are also seen in Dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases. These are likely to play a role in protein interactions.


Pssm-ID: 197731 [Multi-domain]  Cd Length: 100  Bit Score: 37.05  E-value: 6.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 981351976    38 DPSARLVDVRTRAELDwVGRPLvgDGQYLHLEWTRYPGGV-PNAEFVSELKAA-IEPGAPVLFLCRSAARSKLAAVAAAQ 115
Cdd:smart00450   2 DEKVVLLDVRSPEEYE-GGHIP--GAVNIPLSELLDRRGElDILEFEELLKRLgLDKDKPVVVYCRSGNRSAKAAWLLRE 78

                           90       100
                   ....*....|....*....|..
gi 981351976   116 AGFTKAFDLLEGFEGAKDAEGH 137
Cdd:smart00450  79 LGFKNVYLLDGGYKEWSAAGPP 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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