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Conserved domains on  [gi|983303360|ref|WP_060489670|]
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MULTISPECIES: HEAT repeat domain-containing protein [Pseudomonas]

Protein Classification

HEAT repeat domain-containing protein( domain architecture ID 11444215)

HEAT repeat domain-containing protein may function as a scaffold, anchoring and/or adaptor protein

CATH:  1.25.10.110
Gene Ontology:  GO:0005515
PubMed:  35552740|10378263
SCOP:  4001283

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
182-318 2.71e-22

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 90.46  E-value: 2.71e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 182 VRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSLGRLRYAAAL 261
Cdd:COG1413    1 VRRAAARALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAV 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 983303360 262 DALGGLLGHGIANLRKEAALALGELGQARALSVLQAAEADSDPEVRKAVRIALAQLR 318
Cdd:COG1413   81 PALIAALKDEDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
FAD_binding_2 super family cl46878
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 7-315 1.45e-16

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


The actual alignment was detected with superfamily member PRK13800:

Pssm-ID: 481218 [Multi-domain]  Cd Length: 897  Bit Score: 80.28  E-value: 1.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360   7 DNPDILALLPRLDASDAGVRRIALIELADlEDPDGlpwltdalladaaaevraEAARLLEAWEEPevvqalcaaladaAE 86
Cdd:PRK13800 619 DAPSVAELAPYLADPDPGVRRTAVAVLTE-TTPPG------------------FGPALVAALGDG-------------AA 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  87 PVRLAAAQSLSEL-KSLEAGQLILPWVKHADAFVRASALRALRELRLeDAADPALLALADDAAAVRREAVGILGWLKhqp 165
Cdd:PRK13800 667 AVRRAAAEGLRELvEVLPPAPALRDHLGSPDPVVRAAALDVLRALRA-GDAALFAAALGDPDHRVRIEAVRALVSVD--- 742

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 166 aLLALAALAETEPDTEVRRAAIGALGLARDSSV--LPALVAALTDQAWQVREEAATTLGKVGQDQAGPA-LVDALADDFW 242
Cdd:PRK13800 743 -DVESVAGAATDENREVRIAVAKGLATLGAGGApaGDAVRALTGDPDPLVRAAALAALAELGCPPDDVAaATAALRASAW 821

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 983303360 243 QVRLRAARSLGRLRYAAALDALGGLLGHGIANLRKEAALALGEL-GQARALSVLQAAEADSDPEVRKAVRIALA 315
Cdd:PRK13800 822 QVRQGAARALAGAAADVAVPALVEALTDPHLDVRKAAVLALTRWpGDPAARDALTTALTDSDADVRAYARRALA 895
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
182-318 2.71e-22

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 90.46  E-value: 2.71e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 182 VRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSLGRLRYAAAL 261
Cdd:COG1413    1 VRRAAARALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAV 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 983303360 262 DALGGLLGHGIANLRKEAALALGELGQARALSVLQAAEADSDPEVRKAVRIALAQLR 318
Cdd:COG1413   81 PALIAALKDEDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
7-315 1.45e-16

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 80.28  E-value: 1.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360   7 DNPDILALLPRLDASDAGVRRIALIELADlEDPDGlpwltdalladaaaevraEAARLLEAWEEPevvqalcaaladaAE 86
Cdd:PRK13800 619 DAPSVAELAPYLADPDPGVRRTAVAVLTE-TTPPG------------------FGPALVAALGDG-------------AA 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  87 PVRLAAAQSLSEL-KSLEAGQLILPWVKHADAFVRASALRALRELRLeDAADPALLALADDAAAVRREAVGILGWLKhqp 165
Cdd:PRK13800 667 AVRRAAAEGLRELvEVLPPAPALRDHLGSPDPVVRAAALDVLRALRA-GDAALFAAALGDPDHRVRIEAVRALVSVD--- 742

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 166 aLLALAALAETEPDTEVRRAAIGALGLARDSSV--LPALVAALTDQAWQVREEAATTLGKVGQDQAGPA-LVDALADDFW 242
Cdd:PRK13800 743 -DVESVAGAATDENREVRIAVAKGLATLGAGGApaGDAVRALTGDPDPLVRAAALAALAELGCPPDDVAaATAALRASAW 821

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 983303360 243 QVRLRAARSLGRLRYAAALDALGGLLGHGIANLRKEAALALGEL-GQARALSVLQAAEADSDPEVRKAVRIALA 315
Cdd:PRK13800 822 QVRQGAARALAGAAADVAVPALVEALTDPHLDVRKAAVLALTRWpGDPAARDALTTALTDSDADVRAYARRALA 895
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 175-253 2.23e-10

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 56.58  E-value: 2.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  175 ETEPDTEVRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADD-FWQVRLRAARSLG 253
Cdd:pfam13646   9 LRDPDPEVRAAAIRALGRIGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPEALPALLELLRDDdDDVVRAAAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
88-225 1.17e-07

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 50.01  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  88 VRLAAAQSLSELKSLEAGQLILPWVKHADAFVRASALRALRELRLEDAADPallaladdaaavrreavgILGWLKHqpal 167
Cdd:COG1413   32 VRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAVPA------------------LIAALKD---- 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 983303360 168 lalaalaetePDTEVRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVG 225
Cdd:COG1413   90 ----------EDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
192-321 3.80e-07

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 51.77  E-value: 3.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 192 LARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSL------------------- 252
Cdd:PRK13800 616 LALDAPSVAELAPYLADPDPGVRRTAVAVLTETTPPGFGPALVAALGDGAAAVRRAAAEGLrelvevlppapalrdhlgs 695

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 253 -GRLRYAAALDALGGL-----------LGHGIANLRKEAALALGELGQARALSvlqAAEADSDPEVRKAVRIALAQLRGA 320
Cdd:PRK13800 696 pDPVVRAAALDVLRALragdaalfaaaLGDPDHRVRIEAVRALVSVDDVESVA---GAATDENREVRIAVAKGLATLGAG 772


                 .
gi 983303360 321 A 321
Cdd:PRK13800 773 G 773
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
182-318 2.71e-22

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 90.46  E-value: 2.71e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 182 VRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSLGRLRYAAAL 261
Cdd:COG1413    1 VRRAAARALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAV 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 983303360 262 DALGGLLGHGIANLRKEAALALGELGQARALSVLQAAEADSDPEVRKAVRIALAQLR 318
Cdd:COG1413   81 PALIAALKDEDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
150-287 1.96e-18

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 80.06  E-value: 1.96e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 150 VRREAVGILGWLKHQPALLALAALAEtEPDTEVRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQA 229
Cdd:COG1413    1 VRRAAARALGRLGDPAAVPALIAALA-DEDPDVRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEA 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 983303360 230 GPALVDALADDFWQVRLRAARSLGRLRYAAALDALGGLLGHGIANLRKEAALALGELG 287
Cdd:COG1413   80 VPALIAALKDEDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
7-315 1.45e-16

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 80.28  E-value: 1.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360   7 DNPDILALLPRLDASDAGVRRIALIELADlEDPDGlpwltdalladaaaevraEAARLLEAWEEPevvqalcaaladaAE 86
Cdd:PRK13800 619 DAPSVAELAPYLADPDPGVRRTAVAVLTE-TTPPG------------------FGPALVAALGDG-------------AA 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  87 PVRLAAAQSLSEL-KSLEAGQLILPWVKHADAFVRASALRALRELRLeDAADPALLALADDAAAVRREAVGILGWLKhqp 165
Cdd:PRK13800 667 AVRRAAAEGLRELvEVLPPAPALRDHLGSPDPVVRAAALDVLRALRA-GDAALFAAALGDPDHRVRIEAVRALVSVD--- 742

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 166 aLLALAALAETEPDTEVRRAAIGALGLARDSSV--LPALVAALTDQAWQVREEAATTLGKVGQDQAGPA-LVDALADDFW 242
Cdd:PRK13800 743 -DVESVAGAATDENREVRIAVAKGLATLGAGGApaGDAVRALTGDPDPLVRAAALAALAELGCPPDDVAaATAALRASAW 821

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 983303360 243 QVRLRAARSLGRLRYAAALDALGGLLGHGIANLRKEAALALGEL-GQARALSVLQAAEADSDPEVRKAVRIALA 315
Cdd:PRK13800 822 QVRQGAARALAGAAADVAVPALVEALTDPHLDVRKAAVLALTRWpGDPAARDALTTALTDSDADVRAYARRALA 895
HEAT COG1413
HEAT repeat [General function prediction only];
213-321 4.11e-15

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 71.20  E-value: 4.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 213 VREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSLGRLRYAAALDALGGLLGHGIANLRKEAALALGELGQARAL 292
Cdd:COG1413    1 VRRAAARALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAV 80

                         90       100
                 ....*....|....*....|....*....
gi 983303360 293 SVLQAAEADSDPEVRKAVRIALAQLRGAA 321
Cdd:COG1413   81 PALIAALKDEDPEVRRAAAEALGRLGDPA 109
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 175-253 2.23e-10

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 56.58  E-value: 2.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  175 ETEPDTEVRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADD-FWQVRLRAARSLG 253
Cdd:pfam13646   9 LRDPDPEVRAAAIRALGRIGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPEALPALLELLRDDdDDVVRAAAAEALA 88
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 231-315 5.31e-10

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 55.42  E-value: 5.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  231 PALVDALADD-FWQVRLRAARSLGRLRYAAALDALGGLLGHGIANLRKEAALALGELGQARALSVL-QAAEADSDPEVRK 308
Cdd:pfam13646   2 PALLQALLRDpDPEVRAAAIRALGRIGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPEALPALlELLRDDDDDVVRA 81


                  ....*..
gi 983303360  309 AVRIALA 315
Cdd:pfam13646  82 AAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
88-225 1.17e-07

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 50.01  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  88 VRLAAAQSLSELKSLEAGQLILPWVKHADAFVRASALRALRELRLEDAADPallaladdaaavrreavgILGWLKHqpal 167
Cdd:COG1413   32 VRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAVPA------------------LIAALKD---- 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 983303360 168 lalaalaetePDTEVRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGKVG 225
Cdd:COG1413   90 ----------EDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 199-282 1.49e-07

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 48.49  E-value: 1.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  199 LPALVAAL-TDQAWQVREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSLGRLRYAAALDALGGLLGHGIANLRK 277
Cdd:pfam13646   1 LPALLQALlRDPDPEVRAAAIRALGRIGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPEALPALLELLRDDDDDVVR 80


                  ....*
gi 983303360  278 EAALA 282
Cdd:pfam13646  81 AAAAE 85
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
192-321 3.80e-07

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 51.77  E-value: 3.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 192 LARDSSVLPALVAALTDQAWQVREEAATTLGKVGQDQAGPALVDALADDFWQVRLRAARSL------------------- 252
Cdd:PRK13800 616 LALDAPSVAELAPYLADPDPGVRRTAVAVLTETTPPGFGPALVAALGDGAAAVRRAAAEGLrelvevlppapalrdhlgs 695

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 253 -GRLRYAAALDALGGL-----------LGHGIANLRKEAALALGELGQARALSvlqAAEADSDPEVRKAVRIALAQLRGA 320
Cdd:PRK13800 696 pDPVVRAAALDVLRALragdaalfaaaLGDPDHRVRIEAVRALVSVDDVESVA---GAATDENREVRIAVAKGLATLGAG 772


                 .
gi 983303360 321 A 321
Cdd:PRK13800 773 G 773
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
176-317 6.80e-05

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 44.46  E-value: 6.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 176 TEPDTEVRRAAIGALGLARDSSVLPALVAALTDQAWQVREEAATTLGK-VGQDQAGPALVDALADDFWQVR------LRA 248
Cdd:PRK13800 631 ADPDPGVRRTAVAVLTETTPPGFGPALVAALGDGAAAVRRAAAEGLRElVEVLPPAPALRDHLGSPDPVVRaaaldvLRA 710

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360 249 ARSLGRLRYAAAL------------------DALGGLLGHGIANLRK-----EAALALGELGQARALSVLQAAEADSDPE 305
Cdd:PRK13800 711 LRAGDAALFAAALgdpdhrvrieavralvsvDDVESVAGAATDENREvriavAKGLATLGAGGAPAGDAVRALTGDPDPL 790

                        170
                 ....*....|..
gi 983303360 306 VRKAVRIALAQL 317
Cdd:PRK13800 791 VRAAALAALAEL 802
HEAT COG1413
HEAT repeat [General function prediction only];
13-131 1.01e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.84  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  13 ALLPRLDASDAGVRRIALIELADLEDPDGLPWLtDALLADAAAEVRAEAARLLEAWEEPEVVQALCAALADAAEPVRLAA 92
Cdd:COG1413   20 ALIAALADEDPDVRAAAARALGRLGDPRAVPAL-LEALKDPDPEVRAAAAEALGRIGDPEAVPALIAALKDEDPEVRRAA 98

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 983303360  93 AQSLSELKSLEAGQLILPWVKHADAFVRASALRALRELR 131
Cdd:COG1413   99 AEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 150-222 4.62e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 35.78  E-value: 4.62e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 983303360  150 VRREAVGILGWLKHqPALLALAALAETEPDTEVRRAAIGALGLARDSSVLPALVAAL-TDQAWQVREEAATTLG 222
Cdd:pfam13646  16 VRAAAIRALGRIGD-PEAVPALLELLKDEDPAVRRAAAEALGKIGDPEALPALLELLrDDDDDVVRAAAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
25-162 6.34e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 36.53  E-value: 6.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983303360  25 VRRIALIELADLEDPDGLPWLtDALLADAAAEVRAEAARLLEAWEEPEVVQALCAALADAAEPVRLAAAQSLSELKSLEA 104
Cdd:COG1413    1 VRRAAARALGRLGDPAAVPAL-IAALADEDPDVRAAAARALGRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEA 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 983303360 105 GQLILPWVKHADAFVRASALRALRELRLEDAADPALLALADDAAAVRREAVGILGWLK 162
Cdd:COG1413   80 VPALIAALKDEDPEVRRAAAEALGRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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