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Conserved domains on  [gi|983415053|ref|WP_060580243|]
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MULTISPECIES: hypothetical protein [Enterobacter]

Protein Classification

CMD domain-containing protein( domain architecture ID 10008969)

uncharaterized CMD domain-containing protein similar to Escherichia coli YciW protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YciW1 COG4950
N-terminal domain of uncharacterized protein YciW (function unknown) [Function unknown];
78-192 5.37e-32

N-terminal domain of uncharacterized protein YciW (function unknown) [Function unknown];


:

Pssm-ID: 443977  Cd Length: 177  Bit Score: 117.72  E-value: 5.37e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983415053  78 HTLSAYDRLSTALTVAQACGVQRLCNHYAALLAPLPGP--------DSSRESNRRLAEITQYARQLASSPDVIDDKAQNQ 149
Cdd:COG4950   50 GGLSLAERLAVALFVARLHGAQALAAHYAARLAPLPAPalaaaadpDAAAELDPRLAAALAHARLLTLRPREATPAALQA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 983415053 150 LDEVGLTTYDIVLINQIIGFVGFQARVVAVFQALLGHPVRWLP 192
Cdd:COG4950  130 LLDAGLSTPDIVTLSQLIAFVSYQARVVAGLRALAGLPAAAAG 172
ahpD_dom super family cl00460
alkylhydroperoxidase AhpD family core domain; This model represents a 51-residue core region ...
 262-326 4.56e-03

alkylhydroperoxidase AhpD family core domain; This model represents a 51-residue core region of homology among a family of mostly uncharacterized proteins of 110 to 227 amino acids. Most members of this family contain the motif EXXXXXX[SA]XXXXXC[VIL]XCXXXH. Members of the family include the alkylhydroperoxidase AhpD of Mycobacterium tuberculosis, a macrophage infectivity potentiator peptide of Legionella pneumophila, and an uncharacterized peptide in the tetrachloroethene reductive dehalogenase operon of Dehalospirillum multivorans. We suggest that many peptides containing this domain may have alkylhydroperoxidase or related antioxidant activity. [Unknown function, General]


The actual alignment was detected with superfamily member TIGR04030:

Pssm-ID: 469777  Cd Length: 185  Bit Score: 37.46  E-value: 4.56e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 983415053  262 PLSEGPASSMISAARALlVASPDRFSAAQLTPLTGSGLSPEKAINLLTRDAFYGWLDRLRVALGK 326
Cdd:TIGR04030 121 DLGSERWQAIIDAAAAL-SATPAAFNAAHVAALRAQGLDDLAIVDLIQSAAFFNWANRLMLTLGE 184
 
Name Accession Description Interval E-value
YciW1 COG4950
N-terminal domain of uncharacterized protein YciW (function unknown) [Function unknown];
78-192 5.37e-32

N-terminal domain of uncharacterized protein YciW (function unknown) [Function unknown];


Pssm-ID: 443977  Cd Length: 177  Bit Score: 117.72  E-value: 5.37e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983415053  78 HTLSAYDRLSTALTVAQACGVQRLCNHYAALLAPLPGP--------DSSRESNRRLAEITQYARQLASSPDVIDDKAQNQ 149
Cdd:COG4950   50 GGLSLAERLAVALFVARLHGAQALAAHYAARLAPLPAPalaaaadpDAAAELDPRLAAALAHARLLTLRPREATPAALQA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 983415053 150 LDEVGLTTYDIVLINQIIGFVGFQARVVAVFQALLGHPVRWLP 192
Cdd:COG4950  130 LLDAGLSTPDIVTLSQLIAFVSYQARVVAGLRALAGLPAAAAG 172
perox_Avi_7169 TIGR04030
alkylhydroperoxidase domain protein, Avi_7169 family; Members of this family represent a ...
 262-326 4.56e-03

alkylhydroperoxidase domain protein, Avi_7169 family; Members of this family represent a narrow clade that falls within a family of alkylhydroperoxidase-related proteins, fused to or adjacent to a sequence described by TIGR04029. These two partners occur almost always in the context of a putative FMN-dependent luciferase-like monooxygenase (LLM) (TIGR04027), and an ABC transporter in which TIGR04028 models the substrate-binding protein.


Pssm-ID: 188545  Cd Length: 185  Bit Score: 37.46  E-value: 4.56e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 983415053  262 PLSEGPASSMISAARALlVASPDRFSAAQLTPLTGSGLSPEKAINLLTRDAFYGWLDRLRVALGK 326
Cdd:TIGR04030 121 DLGSERWQAIIDAAAAL-SATPAAFNAAHVAALRAQGLDDLAIVDLIQSAAFFNWANRLMLTLGE 184
 
Name Accession Description Interval E-value
YciW1 COG4950
N-terminal domain of uncharacterized protein YciW (function unknown) [Function unknown];
78-192 5.37e-32

N-terminal domain of uncharacterized protein YciW (function unknown) [Function unknown];


Pssm-ID: 443977  Cd Length: 177  Bit Score: 117.72  E-value: 5.37e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 983415053  78 HTLSAYDRLSTALTVAQACGVQRLCNHYAALLAPLPGP--------DSSRESNRRLAEITQYARQLASSPDVIDDKAQNQ 149
Cdd:COG4950   50 GGLSLAERLAVALFVARLHGAQALAAHYAARLAPLPAPalaaaadpDAAAELDPRLAAALAHARLLTLRPREATPAALQA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 983415053 150 LDEVGLTTYDIVLINQIIGFVGFQARVVAVFQALLGHPVRWLP 192
Cdd:COG4950  130 LLDAGLSTPDIVTLSQLIAFVSYQARVVAGLRALAGLPAAAAG 172
perox_Avi_7169 TIGR04030
alkylhydroperoxidase domain protein, Avi_7169 family; Members of this family represent a ...
 262-326 4.56e-03

alkylhydroperoxidase domain protein, Avi_7169 family; Members of this family represent a narrow clade that falls within a family of alkylhydroperoxidase-related proteins, fused to or adjacent to a sequence described by TIGR04029. These two partners occur almost always in the context of a putative FMN-dependent luciferase-like monooxygenase (LLM) (TIGR04027), and an ABC transporter in which TIGR04028 models the substrate-binding protein.


Pssm-ID: 188545  Cd Length: 185  Bit Score: 37.46  E-value: 4.56e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 983415053  262 PLSEGPASSMISAARALlVASPDRFSAAQLTPLTGSGLSPEKAINLLTRDAFYGWLDRLRVALGK 326
Cdd:TIGR04030 121 DLGSERWQAIIDAAAAL-SATPAAFNAAHVAALRAQGLDDLAIVDLIQSAAFFNWANRLMLTLGE 184
peroxid_rel TIGR01926
uncharacterized peroxidase-related enzyme; This protein family with length of about 200 amino ...
 279-325 4.57e-03

uncharacterized peroxidase-related enzyme; This protein family with length of about 200 amino acids. One member, from Myxococcus xanthus, is a selenoprotein, with an otherwise conserved Cys replaced by Sec. This family is drawn narrowly enough to suggest that These proteins contain a domain described by TIGR00778, with a CxxCxxxHxxxxxxxG motif. Some members of that family are known to act as peroxidases or correlate with resistance to oxidative stress.


Pssm-ID: 130981 [Multi-domain]  Cd Length: 177  Bit Score: 37.39  E-value: 4.57e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 983415053  279 LVASPDRFSAAQLTPLTGSGLSPEKAINLLTRDAFYGWLDRLRVALG 325
Cdd:TIGR01926 125 LTATPAKVNEADFAALRAAGFSDLDILDLIHSVAFFNWANRLMLALG 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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