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Conserved domains on  [gi|1011724766|ref|WP_062568504|]
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MULTISPECIES: cytochrome c5 family protein [Pseudoalteromonas]

Protein Classification

c-type cytochrome( domain architecture ID 10007114)

c-type cytochrome is an electron carrier protein that contains one or more heme groups; such as cytochrome c5 and cytochrome c-555, both of which bind 1 heme group per subunit

CATH:  1.10.760.10
Gene Ontology:  GO:0046872|GO:0009055|GO:0020037
PubMed:  10647174|12594933|18568041|10395550|31252007|22723177
SCOP:  3000815

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CytC5 COG3245
Cytochrome c5 [Energy production and conversion];
32-129 1.74e-46

Cytochrome c5 [Energy production and conversion];


:

Pssm-ID: 442476 [Multi-domain]  Cd Length: 108  Bit Score: 145.98  E-value: 1.74e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011724766  32 RLAPIGSVYLegdkaAAAAEPTGPRSGEQVYQAACFACHGTGALGAPK--SADDWAPRIAKGKDTLLDHAINGFNAMPPK 109
Cdd:COG3245    14 RIAPVGAVAL-----AAAAAAAAARSGEAVYNATCAACHATGVAGAPKlgDKAAWAPRIAKGMDTLLKHAINGFNAMPPK 88

                          90       100
                  ....*....|....*....|
gi 1011724766 110 GTCMDCSDEEISAAIDFMTS 129
Cdd:COG3245    89 GGCADLSDDEVKAAVDYMVN 108
 
Name Accession Description Interval E-value
CytC5 COG3245
Cytochrome c5 [Energy production and conversion];
32-129 1.74e-46

Cytochrome c5 [Energy production and conversion];


Pssm-ID: 442476 [Multi-domain]  Cd Length: 108  Bit Score: 145.98  E-value: 1.74e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011724766  32 RLAPIGSVYLegdkaAAAAEPTGPRSGEQVYQAACFACHGTGALGAPK--SADDWAPRIAKGKDTLLDHAINGFNAMPPK 109
Cdd:COG3245    14 RIAPVGAVAL-----AAAAAAAAARSGEAVYNATCAACHATGVAGAPKlgDKAAWAPRIAKGMDTLLKHAINGFNAMPPK 88

                          90       100
                  ....*....|....*....|
gi 1011724766 110 GTCMDCSDEEISAAIDFMTS 129
Cdd:COG3245    89 GGCADLSDDEVKAAVDYMVN 108
Cytochrome_CBB3 pfam13442
Cytochrome C oxidase, cbb3-type, subunit III;
55-127 1.10e-18

Cytochrome C oxidase, cbb3-type, subunit III;


Pssm-ID: 463879 [Multi-domain]  Cd Length: 67  Bit Score: 73.98  E-value: 1.10e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1011724766  55 PRSGEQVYQAACFACHGTGALGAPKSADDWAPriakgkDTLLDHAINGFNAMPPKGTcmDCSDEEISAAIDFM 127
Cdd:pfam13442   3 AAAGEALYAANCASCHGTGGAGPSLAGRALPP------EALVDIIRNGKGAMPAFGG--DLSDEELEALAAYL 67
CxxCH_TIGR02603 TIGR02603
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ...
 58-101 8.20e-03

putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190).


Pssm-ID: 274224  Cd Length: 133  Bit Score: 34.26  E-value: 8.20e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1011724766  58 GEQVYQAACFACHGTGALGAPKSAD--DWApriAKGKDTLLDHAIN 101
Cdd:TIGR02603   6 GKAVFAKVCYLCHRIGGQGVDFGPNltTVG---TKGKEYLLEAILD 48
 
Name Accession Description Interval E-value
CytC5 COG3245
Cytochrome c5 [Energy production and conversion];
32-129 1.74e-46

Cytochrome c5 [Energy production and conversion];


Pssm-ID: 442476 [Multi-domain]  Cd Length: 108  Bit Score: 145.98  E-value: 1.74e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011724766  32 RLAPIGSVYLegdkaAAAAEPTGPRSGEQVYQAACFACHGTGALGAPK--SADDWAPRIAKGKDTLLDHAINGFNAMPPK 109
Cdd:COG3245    14 RIAPVGAVAL-----AAAAAAAAARSGEAVYNATCAACHATGVAGAPKlgDKAAWAPRIAKGMDTLLKHAINGFNAMPPK 88

                          90       100
                  ....*....|....*....|
gi 1011724766 110 GTCMDCSDEEISAAIDFMTS 129
Cdd:COG3245    89 GGCADLSDDEVKAAVDYMVN 108
Cytochrome_CBB3 pfam13442
Cytochrome C oxidase, cbb3-type, subunit III;
55-127 1.10e-18

Cytochrome C oxidase, cbb3-type, subunit III;


Pssm-ID: 463879 [Multi-domain]  Cd Length: 67  Bit Score: 73.98  E-value: 1.10e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1011724766  55 PRSGEQVYQAACFACHGTGALGAPKSADDWAPriakgkDTLLDHAINGFNAMPPKGTcmDCSDEEISAAIDFM 127
Cdd:pfam13442   3 AAAGEALYAANCASCHGTGGAGPSLAGRALPP------EALVDIIRNGKGAMPAFGG--DLSDEELEALAAYL 67
CccA COG2010
Cytochrome c, mono- and diheme variants [Energy production and conversion];
27-129 4.94e-05

Cytochrome c, mono- and diheme variants [Energy production and conversion];


Pssm-ID: 441613 [Multi-domain]  Cd Length: 169  Bit Score: 40.70  E-value: 4.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011724766  27 DAIKKRLAPIGSVYLEGDKAAAAAEPTGPRSGEQVYQAACFACHGTGALGAPKSADDWAPRIAKGKD--TLLDHAINGF- 103
Cdd:COG2010    61 AAALALALLLALLLAAAAADAPAADAEALARGKALYEQNCAACHGADGKGGLGAAPNLTDDALYGGDpeALVETILNGRp 140

                          90       100
                  ....*....|....*....|....*..
gi 1011724766 104 -NAMPPKGTCMdcSDEEISAAIDFMTS 129
Cdd:COG2010   141 gGAMPAFGGQL--SDEEIAALAAYLRS 165
CytC553 COG2863
Cytochrome c553 [Energy production and conversion];
46-129 7.23e-04

Cytochrome c553 [Energy production and conversion];


Pssm-ID: 442110 [Multi-domain]  Cd Length: 98  Bit Score: 36.25  E-value: 7.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011724766  46 AAAAAEPTGPRSGEQvYQAACFACHGTGALGAPKSAddwAPRIAKGKDTLLDHAINGFNAMPPKGTCM-----DCSDEEI 120
Cdd:COG2863     6 LAAPAAAGDAARGKA-YAAACAACHGADGEGNPGGG---APRLAGQHAEYLVAQLKAFRSGARKNGVMpaiakGLSDEDI 81


                  ....*....
gi 1011724766 121 SAAIDFMTS 129
Cdd:COG2863    82 KALAAYIAS 90
Cytochrom_C pfam00034
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ...
 58-127 3.77e-03

Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.


Pssm-ID: 459641 [Multi-domain]  Cd Length: 89  Bit Score: 34.44  E-value: 3.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1011724766  58 GEQVYQAACFACHGTGALGAPKSA------DDWAPRIAKGKDTLLDHAINGF-----NAMPPKGTCMDC--SDEEISAAI 124
Cdd:pfam00034   3 GKKLFAANCAACHGVNGEGAGAGGpdlaglAARYPGDALGAIRENKHAIGGGgvdraGGPPGTGMPAFDglTDEEIADLV 82


                  ...
gi 1011724766 125 DFM 127
Cdd:pfam00034  83 AYL 85
CxxCH_TIGR02603 TIGR02603
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ...
 58-101 8.20e-03

putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190).


Pssm-ID: 274224  Cd Length: 133  Bit Score: 34.26  E-value: 8.20e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1011724766  58 GEQVYQAACFACHGTGALGAPKSAD--DWApriAKGKDTLLDHAIN 101
Cdd:TIGR02603   6 GKAVFAKVCYLCHRIGGQGVDFGPNltTVG---TKGKEYLLEAILD 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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