|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1049 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1599.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVANRFLVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAEMGPDATGVGWVFEYALVDRSG-------KHDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGarkkdggAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 154 AELRSLQDWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 234 SGYLQTLDDFKNIVLKTGDnGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQS 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGE-GVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 314 SLPEGVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 394 GgiAIAVGAMVDAAIVMIENAHKRLEEWEHQHpGEKLSNDTRWKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEGK 473
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEAQHHH-GRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 474 LFGPLAFTKTWSMAGAALLAIVAIPILMGFWILGRIPaESSNPLNRFLIRIYHPLLLKVLHWPKTTLLIALLSILTVAWP 553
Cdd:TIGR00914 476 MFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVA-EKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWI 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 554 LNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQ 633
Cdd:TIGR00914 555 ASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPE 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 634 DQWRPG--MTMEKIVEELDKTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAEQIEGVARSVPGVT 711
Cdd:TIGR00914 635 SQWPEGkkTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAA 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 712 SALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPILAP 791
Cdd:TIGR00914 715 DVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLP 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 792 L-----KQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLE 866
Cdd:TIGR00914 795 LsedarKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQ 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 867 RANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLM 946
Cdd:TIGR00914 875 SATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMIS 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 947 YLRHAIEAEPSlenpqtfsvdkLDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLL 1026
Cdd:TIGR00914 955 FIRKLLEEGPS-----------LDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLL 1023
|
1050 1060
....*....|....*....|...
gi 1031820593 1027 SLFIIPAAYKLMWLYRHRGKRSQ 1049
Cdd:TIGR00914 1024 TLFVLPALYRLVHRRRHKGRKEH 1046
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1049 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1489.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVANRFLVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAEMGPDATGVGWVFEYALVDRSGKHDLAELRSLQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 161 DWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYLQTL 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 241 DDFKNIVLKTgDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGVE 320
Cdd:COG3696 241 EDIENIVVKT-RNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 321 VVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAV 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 401 GAMVDAAIVMIENAHKRLEEWEHQHPGEklsndTRWKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEGKLFGPLAF 480
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRAAGTPR-----ERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMAL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 481 TKTWSMAGAALLAIVAIPILMGFWILGRIPaESSNPLNRFLIRIYHPLLLKVLHWPKTTLLIALLSILTVAWPLNRVGGE 560
Cdd:COG3696 475 TVIFALLGALLLSLTLVPVLASLLLRGKVP-EKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 561 FLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQWRPGM 640
Cdd:COG3696 554 FLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 641 TMEKIVEELDKTV-RLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAEQIEGVARSVPGVTSALAERLV 719
Cdd:COG3696 634 TKEELIAEMREALeQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 720 GGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPILAPLKQQIVLG 799
Cdd:COG3696 714 GLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 800 DVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLERANQKLKLMVPMT 879
Cdd:COG3696 794 QVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 880 LMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLE 959
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLR 953
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 960 npqtfsvdkldEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKlmW 1039
Cdd:COG3696 954 -----------EAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYL--L 1020
|
1050
....*....|
gi 1031820593 1040 LYRHRGKRSQ 1049
Cdd:COG3696 1021 FGRRRLRRAA 1030
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1037 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 706.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVAnrflVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:pfam00873 1 MSKFFIRRPIF----TLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVS-AEMGPDATGVGWVFEYALVDRSGKHDLAELRSL 159
Cdd:pfam00873 77 YMSSQSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 160 QDWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYLQT 239
Cdd:pfam00873 157 ADTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 240 LDDFKNIVLKtGDNGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGV 319
Cdd:pfam00873 237 AEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 320 EVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIA 399
Cdd:pfam00873 315 EIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 400 VGAMVDAAIVMIENAHKRLEEwEHQHPGEKlsndtrwkiITEASVEVGPALFISLLIITLSFIPIFTLEGQEGKLFGPLA 479
Cdd:pfam00873 395 IGLVVDDAIVVVENIERVLEE-NGLKPLEA---------AYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 480 FTKTWSMAGAALLAIVAIPILMGfWILGRIPAE-------SSNPLNRFLIRIYHPLLLKVLHWPKTTLLIALLSILTVAW 552
Cdd:pfam00873 465 ITIVLAILLSVLVALTLTPALCA-TLLKPRREPkhggffrWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVW 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 553 PLNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAEtATDSAPLEMVETTIQLKP 632
Cdd:pfam00873 544 LFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKP 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 633 QDQWR-PGMTMEKIVEELDKTVR-LPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAEQIEGVARSVPGV 710
Cdd:pfam00873 623 WKERPgPEKSVQALIERLRKALKqIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 711 TSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPILA 790
Cdd:pfam00873 703 SDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRN 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 791 PLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLERANQ 870
Cdd:pfam00873 783 PYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGN 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 871 KLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRH 950
Cdd:pfam00873 863 SLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANE 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 951 AIEAEPSlenpqtfsvdKLDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI 1030
Cdd:pfam00873 943 LREQEGK----------SLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLV 1012
|
....*..
gi 1031820593 1031 IPAAYKL 1037
Cdd:pfam00873 1013 VPVFYVL 1019
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1037 |
4.14e-115 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 379.75 E-value: 4.14e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 4 WIIRRSVANRFLVMMAALFlsiwGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVR 83
Cdd:NF033617 3 VFIKRPVATLLLSLLILLL----GLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 84 GFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAG-----VSAEMGPDATGVGWV-FEYALVDRSGKHDLAELR 157
Cdd:NF033617 79 SQSSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEapdppVYRKANSADTPIMYIgLTSEEMPRGQLTDYAERV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 158 slqdwfLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYL 237
Cdd:NF033617 159 ------LAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 238 QTLDDFKNIVLKTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILrSGKNAREMISAVKEKLASLQSSLPE 317
Cdd:NF033617 233 KTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQ-PGANPIEVADEIRALLPELQETLPK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 318 GVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIA 397
Cdd:NF033617 312 NIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 398 IAVGAMVDAAIVMIENAHKRLEEWEhqHPGEKLSNDTRwkiiteasvEVGpalfISLLIITLS----FIPIFTLEGQEGK 473
Cdd:NF033617 392 LAIGLVVDDAIVVVENIHRHIEEGE--SPLEAALKGAR---------EIG----FTVIAMTLTlvavYLPILFMGGLTGR 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 474 LFGPLAFTktwsMAGAALL-AIVAIPI--LMGFWILGRIPAES--SNPLNRFLIRI---YHPLLLKVLHWPKTTLLIALL 545
Cdd:NF033617 457 LFREFAVT----LAGAVIIsGIVALTLtpMMCSRLLKANEKPGrfARAVDRFFDGLtarYGRGLKWVLKHRPLTLVVALA 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 546 SILTVAWPLNRVGGEFLPQINEGDLLympSTLPGISAAQAADMLQKTDKL---IMTVPEVARVFGKTGKAETATDSAPLE 622
Cdd:NF033617 533 TLALLPLLYVFIPKELAPSEDRGVIF---GMIQAPQSISLDYMSAKMRDVekiLSSDPEVQSLTSFNGVGGNPGDNTGFG 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 623 MvettIQLKPQDQWRpgMTMEKIVEELDKTV-RLPGLA-NLW-VPPIRnridmLSTGIKSPIGIKV-SGTNLADIDAIAE 698
Cdd:NF033617 610 I----INLKPWDERD--VSAQEIIDRLRPKLaKVPGMDlFLFpLQDLP-----GGAGSSLPQYQVTlTPSDYDSLFTWAE 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 699 QIEGVARSVPGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRD 778
Cdd:NF033617 679 KLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRL 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 779 SPETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWI-YIDARDRDMVSVVHDLQQAigKEVKLKPGISVS 857
Cdd:NF033617 759 NPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLsFNLAPGVSLGEAIEALDQA--AKELLPSGISGS 836
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 858 YSGQFELLERANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVA 937
Cdd:NF033617 837 FQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLV 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 938 AEFGVVMLMYlrhAIEAEpsLENPQTFsvdklDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMI 1017
Cdd:NF033617 917 KKNGILMVEF---ANELQ--RHQGLSR-----REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIV 986
|
1050 1060
....*....|....*....|
gi 1031820593 1018 GGMITAPLLSLFIIPAAYKL 1037
Cdd:NF033617 987 GGLGVGTLFTLFVLPVVYLL 1006
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
6-1038 |
1.00e-60 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 225.48 E-value: 1.00e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 6 IRRSVanrfLVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRGF 85
Cdd:PRK09579 8 IRRPV----LASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 86 SQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAG----VSAEMGPDATGVGWVFEYalvdrSGKHDLAELRSLQD 161
Cdd:PRK09579 84 SRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDaedpVLSKEAADASALMYISFY-----SEEMSNPQITDYLS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 162 WFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVElaeAEYMV---RASGYLQ 238
Cdd:PRK09579 159 RVIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVtsiNASTELK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 239 TLDDFKNIVLKT-GDNgvPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILRSGkNAREMISAVKEKLASLQSSLPE 317
Cdd:PRK09579 236 SAEAFAAIPVKTsGDS--RVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSA-NPLDVIKEVRAIMPELESQLPP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 318 GVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIA 397
Cdd:PRK09579 313 NLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 398 IAVGAMVDAAIVMIENAHKRLEEwehqhpgeklsNDTRWKIITEASVEVgpALFISLLIITLS--FIPIFTLEGQEGKLF 475
Cdd:PRK09579 393 LAIGLVVDDAIVVVENIHRHIEE-----------GKSPFDAALEGAREI--AMPVVSMTITLAavYAPIGFLTGLTGALF 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 476 GPLAFTktwsMAGAALLA-IVAIPI--LMGFWILGR--IPAESSNPLNRFLIRI---YHPLLLKVLHWPKTTLLIALLSI 547
Cdd:PRK09579 460 KEFALT----LAGAVIISgIVALTLspMMCALLLRHeeNPSGLAHRLDRLFERLkqrYQRALHGTLNTRPVVLVFAVIVL 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 548 LTVAWPLNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGkaetatdsapLEMVETT 627
Cdd:PRK09579 536 ALIPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQING----------FNGVQSG 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 628 IQ---LKPQDQwRPGMTMEKIVEELDKTVRLPGLANLWVppirNRIDMLSTGIKSPIGIKVSGTNlaDIDAIAEQIEGV- 703
Cdd:PRK09579 606 IGgflLKPWNE-RERTQMELLPLVQAKLEEIPGLQIFGF----NLPSLPGTGEGLPFQFVINTAN--DYESLLQVAQRVk 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 704 ARSVPGVTSAlaerlvggrYLDID-----------IHREKAARYGMTVGDVQLFVSSAIGGAMVGE-TVEGvERYPINIR 771
Cdd:PRK09579 679 QRAQESGKFA---------FLDIDlafdkpevvvdIDRAKAAQMGVSMQDLGGTLATLLGEGEINRfTIDG-RSYKVIAQ 748
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 772 YPQSYRDSPETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIyidaRDRDMVSVVHDLQ--QAIGKEvK 849
Cdd:PRK09579 749 VERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQLNQFQQLNSAII----SGFPIVSMGEAIEtvQQIARE-E 823
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 850 LKPGISVSYSGQFELLERANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTG 929
Cdd:PRK09579 824 APEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVG 903
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 930 FIALAGVAAEFGVVMlmylrhaIEAEPSLENPQTFSVdklDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVM 1009
Cdd:PRK09579 904 LVTLIGLISKHGILI-------VEFANQLRHEQGLSR---REAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSR 973
|
1050 1060
....*....|....*....|....*....
gi 1031820593 1010 SRIAAPMIGGMITAPLLSLFIIPAAYKLM 1038
Cdd:PRK09579 974 FDIGLVIATGMSIGTLFTLFVLPCIYTLL 1002
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1049 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1599.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVANRFLVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAEMGPDATGVGWVFEYALVDRSG-------KHDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGarkkdggAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 154 AELRSLQDWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 234 SGYLQTLDDFKNIVLKTGDnGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQS 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGE-GVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 314 SLPEGVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 394 GgiAIAVGAMVDAAIVMIENAHKRLEEWEHQHpGEKLSNDTRWKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEGK 473
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEAQHHH-GRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 474 LFGPLAFTKTWSMAGAALLAIVAIPILMGFWILGRIPaESSNPLNRFLIRIYHPLLLKVLHWPKTTLLIALLSILTVAWP 553
Cdd:TIGR00914 476 MFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVA-EKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWI 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 554 LNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQ 633
Cdd:TIGR00914 555 ASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPE 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 634 DQWRPG--MTMEKIVEELDKTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAEQIEGVARSVPGVT 711
Cdd:TIGR00914 635 SQWPEGkkTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAA 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 712 SALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPILAP 791
Cdd:TIGR00914 715 DVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLP 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 792 L-----KQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLE 866
Cdd:TIGR00914 795 LsedarKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQ 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 867 RANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLM 946
Cdd:TIGR00914 875 SATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMIS 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 947 YLRHAIEAEPSlenpqtfsvdkLDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLL 1026
Cdd:TIGR00914 955 FIRKLLEEGPS-----------LDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLL 1023
|
1050 1060
....*....|....*....|...
gi 1031820593 1027 SLFIIPAAYKLMWLYRHRGKRSQ 1049
Cdd:TIGR00914 1024 TLFVLPALYRLVHRRRHKGRKEH 1046
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1049 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1489.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVANRFLVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAEMGPDATGVGWVFEYALVDRSGKHDLAELRSLQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 161 DWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYLQTL 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 241 DDFKNIVLKTgDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGVE 320
Cdd:COG3696 241 EDIENIVVKT-RNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 321 VVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAV 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 401 GAMVDAAIVMIENAHKRLEEWEHQHPGEklsndTRWKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEGKLFGPLAF 480
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRAAGTPR-----ERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMAL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 481 TKTWSMAGAALLAIVAIPILMGFWILGRIPaESSNPLNRFLIRIYHPLLLKVLHWPKTTLLIALLSILTVAWPLNRVGGE 560
Cdd:COG3696 475 TVIFALLGALLLSLTLVPVLASLLLRGKVP-EKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 561 FLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQWRPGM 640
Cdd:COG3696 554 FLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGR 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 641 TMEKIVEELDKTV-RLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAEQIEGVARSVPGVTSALAERLV 719
Cdd:COG3696 634 TKEELIAEMREALeQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 720 GGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPILAPLKQQIVLG 799
Cdd:COG3696 714 GLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLS 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 800 DVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLERANQKLKLMVPMT 879
Cdd:COG3696 794 QVADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 880 LMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLE 959
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLR 953
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 960 npqtfsvdkldEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKlmW 1039
Cdd:COG3696 954 -----------EAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYL--L 1020
|
1050
....*....|
gi 1031820593 1040 LYRHRGKRSQ 1049
Cdd:COG3696 1021 FGRRRLRRAA 1030
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1037 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 706.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVAnrflVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:pfam00873 1 MSKFFIRRPIF----TLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVS-AEMGPDATGVGWVFEYALVDRSGKHDLAELRSL 159
Cdd:pfam00873 77 YMSSQSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 160 QDWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYLQT 239
Cdd:pfam00873 157 ADTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 240 LDDFKNIVLKtGDNGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGV 319
Cdd:pfam00873 237 AEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 320 EVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIA 399
Cdd:pfam00873 315 EIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 400 VGAMVDAAIVMIENAHKRLEEwEHQHPGEKlsndtrwkiITEASVEVGPALFISLLIITLSFIPIFTLEGQEGKLFGPLA 479
Cdd:pfam00873 395 IGLVVDDAIVVVENIERVLEE-NGLKPLEA---------AYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 480 FTKTWSMAGAALLAIVAIPILMGfWILGRIPAE-------SSNPLNRFLIRIYHPLLLKVLHWPKTTLLIALLSILTVAW 552
Cdd:pfam00873 465 ITIVLAILLSVLVALTLTPALCA-TLLKPRREPkhggffrWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVW 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 553 PLNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAEtATDSAPLEMVETTIQLKP 632
Cdd:pfam00873 544 LFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKP 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 633 QDQWR-PGMTMEKIVEELDKTVR-LPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAEQIEGVARSVPGV 710
Cdd:pfam00873 623 WKERPgPEKSVQALIERLRKALKqIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 711 TSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPILA 790
Cdd:pfam00873 703 SDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRN 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 791 PLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLERANQ 870
Cdd:pfam00873 783 PYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGN 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 871 KLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRH 950
Cdd:pfam00873 863 SLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANE 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 951 AIEAEPSlenpqtfsvdKLDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI 1030
Cdd:pfam00873 943 LREQEGK----------SLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLV 1012
|
....*..
gi 1031820593 1031 IPAAYKL 1037
Cdd:pfam00873 1013 VPVFYVL 1019
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1047 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 641.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 1 MIEWIIRRSVAnrflVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAK 80
Cdd:COG0841 3 LSRFFIRRPVA----AIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVS----AEMGPDATGVGWVfeyALvdRSGKHDLAEL 156
Cdd:COG0841 79 YITSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEppgvTKVNPSDFPVMVL---AL--SSDDLDELEL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 157 RSLQDWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGY 236
Cdd:COG0841 154 SDYAERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 237 LQTLDDFKNIVLKTgDNGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQSSLP 316
Cdd:COG0841 234 LKTPEEFENIVIRT-NDGSVVRLGDVARVEDGAEDYRSIARLNGK-PAVGLAIQKQPGANALEVADAVRAKLEELQASLP 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 317 EGVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGI 396
Cdd:COG0841 312 EGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFAL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 397 AIAVGAMVDAAIVMIENAHKRLEEwehqhpGEklsndTRWKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEGKLFG 476
Cdd:COG0841 392 VLAIGIVVDDAIVVVENIERHMEE------GL-----SPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFR 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 477 PLAFTKTWSMAGAALLAIVAIPiLMGFWILGRIPAESSNPLNRF-------LIRIYHPLLLKVLHWPKTTLLIALLSILT 549
Cdd:COG0841 461 QFALTVAIALLISLFVALTLTP-ALCARLLKPHPKGKKGRFFRAfnrgfdrLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 550 VAWPLNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAETATDSApleMVETTIQ 629
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSN---SGTIFVT 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 630 LKPQDQwRPgMTMEKIVEEL-DKTVRLPGL-ANLWVPPIRNRidmlstGIKSPIGIKVSGTNLADIDAIAEQIEGVARSV 707
Cdd:COG0841 617 LKPWDE-RD-RSADEIIARLrEKLAKIPGArVFVFQPPAGGL------GSGAPIEVQLQGDDLEELAAAAEKLLAALRQI 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 708 PGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLP 787
Cdd:COG0841 689 PGLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLY 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 788 ILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYID-ARDRDMVSVVHDLQQAIgKEVKLKPGISVSYSGQFELLE 866
Cdd:COG0841 769 VRTPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANlAPGVSLGEALAAIEELA-AELKLPPGVSIEFTGQAEEEQ 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 867 RANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLM 946
Cdd:COG0841 848 ESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVD 927
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 947 YLRHAIEAEPSLEnpqtfsvdkldEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLL 1026
Cdd:COG0841 928 FANQLREEGMSLR-----------EAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLL 996
|
1050 1060
....*....|....*....|.
gi 1031820593 1027 SLFIIPAAYklMWLYRHRGKR 1047
Cdd:COG0841 997 TLFVVPVLY--VLLDRLRRRL 1015
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1037 |
4.14e-115 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 379.75 E-value: 4.14e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 4 WIIRRSVANRFLVMMAALFlsiwGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVR 83
Cdd:NF033617 3 VFIKRPVATLLLSLLILLL----GLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 84 GFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAG-----VSAEMGPDATGVGWV-FEYALVDRSGKHDLAELR 157
Cdd:NF033617 79 SQSSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEapdppVYRKANSADTPIMYIgLTSEEMPRGQLTDYAERV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 158 slqdwfLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYL 237
Cdd:NF033617 159 ------LAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 238 QTLDDFKNIVLKTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILrSGKNAREMISAVKEKLASLQSSLPE 317
Cdd:NF033617 233 KTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQ-PGANPIEVADEIRALLPELQETLPK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 318 GVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIA 397
Cdd:NF033617 312 NIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 398 IAVGAMVDAAIVMIENAHKRLEEWEhqHPGEKLSNDTRwkiiteasvEVGpalfISLLIITLS----FIPIFTLEGQEGK 473
Cdd:NF033617 392 LAIGLVVDDAIVVVENIHRHIEEGE--SPLEAALKGAR---------EIG----FTVIAMTLTlvavYLPILFMGGLTGR 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 474 LFGPLAFTktwsMAGAALL-AIVAIPI--LMGFWILGRIPAES--SNPLNRFLIRI---YHPLLLKVLHWPKTTLLIALL 545
Cdd:NF033617 457 LFREFAVT----LAGAVIIsGIVALTLtpMMCSRLLKANEKPGrfARAVDRFFDGLtarYGRGLKWVLKHRPLTLVVALA 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 546 SILTVAWPLNRVGGEFLPQINEGDLLympSTLPGISAAQAADMLQKTDKL---IMTVPEVARVFGKTGKAETATDSAPLE 622
Cdd:NF033617 533 TLALLPLLYVFIPKELAPSEDRGVIF---GMIQAPQSISLDYMSAKMRDVekiLSSDPEVQSLTSFNGVGGNPGDNTGFG 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 623 MvettIQLKPQDQWRpgMTMEKIVEELDKTV-RLPGLA-NLW-VPPIRnridmLSTGIKSPIGIKV-SGTNLADIDAIAE 698
Cdd:NF033617 610 I----INLKPWDERD--VSAQEIIDRLRPKLaKVPGMDlFLFpLQDLP-----GGAGSSLPQYQVTlTPSDYDSLFTWAE 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 699 QIEGVARSVPGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRD 778
Cdd:NF033617 679 KLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRL 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 779 SPETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWI-YIDARDRDMVSVVHDLQQAigKEVKLKPGISVS 857
Cdd:NF033617 759 NPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLsFNLAPGVSLGEAIEALDQA--AKELLPSGISGS 836
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 858 YSGQFELLERANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVA 937
Cdd:NF033617 837 FQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLV 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 938 AEFGVVMLMYlrhAIEAEpsLENPQTFsvdklDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMI 1017
Cdd:NF033617 917 KKNGILMVEF---ANELQ--RHQGLSR-----REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIV 986
|
1050 1060
....*....|....*....|
gi 1031820593 1018 GGMITAPLLSLFIIPAAYKL 1037
Cdd:NF033617 987 GGLGVGTLFTLFVLPVVYLL 1006
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
20-1035 |
5.50e-81 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 285.86 E-value: 5.50e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 20 ALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRGFSQF-GDSYVYVIFE 98
Cdd:TIGR00915 16 AIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSDSdGSMTITLTFE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 99 DGTDPYWARSRVLEYLNQVQGKLPA-----GVSAEmgpdATGVGWVFEYALVDRSGKHDLAELRSLQDWFLKYELKTIPN 173
Cdd:TIGR00915 96 QGTDPDIAQVQVQNKLQLATPLLPQevqrqGVRVE----KASSNFLMVIGLVSDDGSMTKEDLSDYAASNMVDPLSRLEG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 174 VSEVaSVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASN-QEAGGS-----SVELAEAEYMVRASGYLQTLDDFKNIV 247
Cdd:TIGR00915 172 VGDV-QLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNaQISAGQlgglpAVPGQQLNATIIAQTRLQTPEQFENIL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 248 LKTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGVEVVTTYDR 327
Cdd:TIGR00915 251 LKVNTDGSQVRLKDVARVELGGENYSISARFNGK-PASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGMKYVYPYDT 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 328 SQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMVDAA 407
Cdd:TIGR00915 330 TPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDA 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 408 IVMIENAHKRLEEwEHQHPGEKLSNdtRWKIITEASVEVGpalfislLIITLSFIPIFTLEGQEGKLFGPLAFTKTWSMA 487
Cdd:TIGR00915 410 IVVVENVERVMAE-EGLPPKEATRK--SMGQIQGALVGIA-------MVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 488 GAALLAIVAIPILMGFwILGRIPAES--------SNPLNRFLIRI---YHPLLLKVLHWPKTTLLIALLSILTVAWPLNR 556
Cdd:TIGR00915 480 LSVLVALILTPALCAT-MLKPIEKGEhhekkggfFGWFNRMFDSSthgYENGVGKILRRRGRYLLVYVLLVGGMVFLFVR 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 557 VGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVP--EVARVFGKTGkAETATDSAPLEMVetTIQLKP-Q 633
Cdd:TIGR00915 559 LPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEkaNVESVFTVNG-FSFAGRGQNMGMA--FIRLKDwE 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 634 DQWRPGMTMEKIVEELDK---TVRLPGLANLWVPPIRnridmlstGIKSPIGIKV-----SGTNLADIDAIAEQIEGVAR 705
Cdd:TIGR00915 636 ERTGKENSVFAIAGRATGhfmQIKDAMVIAFVPPAIL--------ELGNATGFDFflqdrAGLGHEALLQARNQLLGLAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 706 SVPGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQ 785
Cdd:TIGR00915 708 QNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINK 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 786 LPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKevKLKPGISVSYSGQ-FEL 864
Cdd:TIGR00915 788 WYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQ--KLPPGFGFSWTGMsYEE 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 865 LERANQKLkLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVVM 944
Cdd:TIGR00915 866 RLSGSQAP-ALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILI 944
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 945 LMYLRHAIEAEPSLEnpqtfsvdkldEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAP 1024
Cdd:TIGR00915 945 VEFAKELMAQGKSIV-----------EAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTAT 1013
|
1050
....*....|.
gi 1031820593 1025 LLSLFIIPAAY 1035
Cdd:TIGR00915 1014 VLAIFFVPLFY 1024
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
6-1038 |
1.00e-60 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 225.48 E-value: 1.00e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 6 IRRSVanrfLVMMAALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRGF 85
Cdd:PRK09579 8 IRRPV----LASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 86 SQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAG----VSAEMGPDATGVGWVFEYalvdrSGKHDLAELRSLQD 161
Cdd:PRK09579 84 SRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDaedpVLSKEAADASALMYISFY-----SEEMSNPQITDYLS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 162 WFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVElaeAEYMV---RASGYLQ 238
Cdd:PRK09579 159 RVIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVtsiNASTELK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 239 TLDDFKNIVLKT-GDNgvPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILRSGkNAREMISAVKEKLASLQSSLPE 317
Cdd:PRK09579 236 SAEAFAAIPVKTsGDS--RVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSA-NPLDVIKEVRAIMPELESQLPP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 318 GVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIA 397
Cdd:PRK09579 313 NLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 398 IAVGAMVDAAIVMIENAHKRLEEwehqhpgeklsNDTRWKIITEASVEVgpALFISLLIITLS--FIPIFTLEGQEGKLF 475
Cdd:PRK09579 393 LAIGLVVDDAIVVVENIHRHIEE-----------GKSPFDAALEGAREI--AMPVVSMTITLAavYAPIGFLTGLTGALF 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 476 GPLAFTktwsMAGAALLA-IVAIPI--LMGFWILGR--IPAESSNPLNRFLIRI---YHPLLLKVLHWPKTTLLIALLSI 547
Cdd:PRK09579 460 KEFALT----LAGAVIISgIVALTLspMMCALLLRHeeNPSGLAHRLDRLFERLkqrYQRALHGTLNTRPVVLVFAVIVL 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 548 LTVAWPLNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGkaetatdsapLEMVETT 627
Cdd:PRK09579 536 ALIPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQING----------FNGVQSG 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 628 IQ---LKPQDQwRPGMTMEKIVEELDKTVRLPGLANLWVppirNRIDMLSTGIKSPIGIKVSGTNlaDIDAIAEQIEGV- 703
Cdd:PRK09579 606 IGgflLKPWNE-RERTQMELLPLVQAKLEEIPGLQIFGF----NLPSLPGTGEGLPFQFVINTAN--DYESLLQVAQRVk 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 704 ARSVPGVTSAlaerlvggrYLDID-----------IHREKAARYGMTVGDVQLFVSSAIGGAMVGE-TVEGvERYPINIR 771
Cdd:PRK09579 679 QRAQESGKFA---------FLDIDlafdkpevvvdIDRAKAAQMGVSMQDLGGTLATLLGEGEINRfTIDG-RSYKVIAQ 748
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 772 YPQSYRDSPETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIyidaRDRDMVSVVHDLQ--QAIGKEvK 849
Cdd:PRK09579 749 VERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQLNQFQQLNSAII----SGFPIVSMGEAIEtvQQIARE-E 823
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 850 LKPGISVSYSGQFELLERANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTG 929
Cdd:PRK09579 824 APEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVG 903
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 930 FIALAGVAAEFGVVMlmylrhaIEAEPSLENPQTFSVdklDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVM 1009
Cdd:PRK09579 904 LVTLIGLISKHGILI-------VEFANQLRHEQGLSR---REAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSR 973
|
1050 1060
....*....|....*....|....*....
gi 1031820593 1010 SRIAAPMIGGMITAPLLSLFIIPAAYKLM 1038
Cdd:PRK09579 974 FDIGLVIATGMSIGTLFTLFVLPCIYTLL 1002
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
20-1048 |
2.36e-60 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 224.73 E-value: 2.36e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 20 ALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFED 99
Cdd:PRK09577 16 SLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 100 GTDPYWARSRVLEYLNQVQGKLP-----AGVSAEMGPDATGVgwvfEYALVDRSGKHDLAELRSLQDWFLKYELKTIPNV 174
Cdd:PRK09577 96 GVNADLAAVEVQNRLKTVEARLPepvrrDGIQVEKAADNIQL----IVSLTSDDGRLTGVELGEYASANVLQALRRVEGV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 175 SEVASVGGvvkEY--QIVVDPMKLSQYGISLGEVKSALDASNQ-----EAGGSSV-ELAEAEYMVRASGYLQTLDDFKNI 246
Cdd:PRK09577 172 GKVQFWGA---EYamRIWPDPVKLAALGLTASDIASAVRAHNArvtigDIGRSAVpDSAPIAATVFADAPLKTPEDFGAI 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 247 VLKTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEgeVAGGVVI-LRSGKNAREMISAVKEKLASLQSSLPEGVEVVTTY 325
Cdd:PRK09577 249 ALRARADGSALYLRDVARIEFGGNDYNYPSYVNGK--TATGMGIkLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 326 DRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMVD 405
Cdd:PRK09577 327 ETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIGILVD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 406 AAIVMIENAHKRLEEwehqhpgEKLS-NDTRWKIITEASvevGPALFISLLIITLsFIPIFTLEGQEGKLFGPLAFTKTW 484
Cdd:PRK09577 407 DAIVVVENVERLMVE-------EGLSpYDATVKAMKQIS---GAIVGITVVLTSV-FVPMAFFGGAVGNIYRQFALSLAV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 485 SMAGAALLAIVAIPILMGFwILGRIPAESSNP------LNRFLIRI---YHPLLLKVLHWPKTTLLIALLSILTVAWPLN 555
Cdd:PRK09577 476 SIGFSAFLALSLTPALCAT-LLKPVDGDHHEKrgffgwFNRFVARStqrYATRVGAILKRPLRWLVVYGALTAAAALLFT 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 556 RVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKA--ETATDSApleMVETTIQlKPQ 633
Cdd:PRK09577 555 RLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNlyGEGPNGG---MIFVTLK-DWK 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 634 DQWRPGMTMEKIVEELDKtvRLPGLANLWV-----PPIRnriDMLSTGikspiGIKVSGTNLADID-----AIAEQIEGV 703
Cdd:PRK09577 631 ERKAARDHVQAIVARINE--RFAGTPNTTVfamnsPALP---DLGSTS-----GFDFRLQDRGGLGyaafvAAREQLLAE 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 704 ARSVPGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETL 783
Cdd:PRK09577 701 GAKDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDV 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 784 RQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTswIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFE 863
Cdd:PRK09577 781 KKLRVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPS--FTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSF 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 864 LLERANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAEFGVV 943
Cdd:PRK09577 859 EERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAIL 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 944 MLMYLRHAIEAEPSLenpqtfsvdkLDEALyRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITA 1023
Cdd:PRK09577 939 IVEVAKDLVAQRMSL----------ADAAL-EAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITA 1007
|
1050 1060
....*....|....*....|....*
gi 1031820593 1024 PLLSLFIIPAAYKLMWLYRHRGKRS 1048
Cdd:PRK09577 1008 TVLAVFLVPLFFVVVGRLFDVGPRR 1032
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
20-1032 |
1.92e-58 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 219.00 E-value: 1.92e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 20 ALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRGFS-QFGDSYVYVIFE 98
Cdd:PRK15127 16 AIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQITLTFE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 99 DGTDPYWARSRVLEYLNQVQGKLPAGVSAE-MGPDATGVGWVFEYALVDRSGKHDLAELRSLQDWFLKYELKTIPNVSEV 177
Cdd:PRK15127 96 SGTDADIAQVQVQNKLQLAMPLLPQEVQQQgVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTSGVGDV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 178 aSVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASN------QEAGGSSVELAEAEYMVRASGYLQTLDDFKNIVLKTG 251
Cdd:PRK15127 176 -QLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNaqvaagQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVN 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 252 DNGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGVEVVTTYDRSQLI 331
Cdd:PRK15127 255 QDGSRVRLRDVAKIELGGENYDIIAEFNGQ-PASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFV 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 332 DRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMVDAAIVMI 411
Cdd:PRK15127 334 KISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVV 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 412 ENAHKRLEEwEHQHPGEKlsndTRWKIITEASVEVGPALFISLLiitlsFIPIFTLEGQEGKLFGPLAFTKTWSMAGAAL 491
Cdd:PRK15127 414 ENVERVMAE-EGLPPKEA----TRKSMGQIQGALVGIAMVLSAV-----FVPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 492 LAIVAIPILMGFwILGRIPAESSNP--------LNRFLIRIYHPLLLKVLHWPKTT---LLIALLSILTVAWPLNRVGGE 560
Cdd:PRK15127 484 VALILTPALCAT-MLKPIAKGDHGEgkkgffgwFNRMFEKSTHHYTDSVGNILRSTgryLVLYLIIVVGMAYLFVRLPSS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 561 FLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMT-----VPEVARV--FGKTGKAETATDSaplemvetTIQLKPQ 633
Cdd:PRK15127 563 FLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTkeknnVESVFAVngFGFAGRGQNTGIA--------FVSLKDW 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 634 DQwRPGmtmekiveELDKTVRLPGLANLWVPPIRnriDMLSTGIKSPIGIKVSGTNLADIDAI------AEQIEGVARSV 707
Cdd:PRK15127 635 AD-RPG--------EENKVEAITMRATRAFSQIK---DAMVFAFNLPAIVELGTATGFDFELIdqaglgHEKLTQARNQL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 708 PGVTSALAERLVGGR--------YLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDS 779
Cdd:PRK15127 703 LGEAAKHPDMLVGVRpngledtpQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRML 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 780 PETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKevKLKPGISVSYS 859
Cdd:PRK15127 783 PDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELAS--KLPTGVGYDWT 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 860 GqFELLER--ANQKLKLMVpMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVA 937
Cdd:PRK15127 861 G-MSYQERlsGNQAPALYA-ISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLS 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 938 AEFGVVMLMYLRHAIEAEPSlenpqtfsvdKLDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMI 1017
Cdd:PRK15127 939 AKNAILIVEFAKDLMDKEGK----------GLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVM 1008
|
1050
....*....|....*
gi 1031820593 1018 GGMITAPLLSLFIIP 1032
Cdd:PRK15127 1009 GGMVTATVLAIFFVP 1023
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
20-1032 |
1.90e-54 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 206.60 E-value: 1.90e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 20 ALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRG-FSQFGDSYVYVIFE 98
Cdd:PRK10555 16 AILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSSGTGQASVTLSFK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 99 DGTDPYWARSRVLEYLNQVQGKLPAGVSAE-MGPDATGVGWVFEYALVDRSG---KHDLAEL--RSLQDwflkyELKTIP 172
Cdd:PRK10555 96 AGTDPDEAVQQVQNQLQSAMRKLPQAVQNQgVTVRKTGDTNILTIAFVSTDGsmdKQDIADYvaSNIQD-----PLSRVN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 173 NVSEVASVGgvvKEY--QIVVDPMKLSQYGISLGEVKSALDASN------QEAGGSSVELAEAEYMVRASGYLQTLDDFK 244
Cdd:PRK10555 171 GVGDIDAYG---SQYsmRIWLDPAKLNSFQMTTKDVTDAIESQNaqiavgQLGGTPSVDKQALNATINAQSLLQTPEQFR 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 245 NIVLKTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEgEVAGGVVILRSGKNAREMISAVKEKLASLQSSLPEGVEVVTT 324
Cdd:PRK10555 248 DITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGK-PASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLEYKVA 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 325 YDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMV 404
Cdd:PRK10555 327 YETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 405 DAAIVMIENAHKRLEEwEHQHPGEKlsndTRWKIITEASVEVGPALFISLLiitlsFIPIFTLEGQEGKLFGPLAFTKTW 484
Cdd:PRK10555 407 DDAIVVVENVERIMSE-EGLTPREA----TRKSMGQIQGALVGIAMVLSAV-----FVPMAFFGGTTGAIYRQFSITIVS 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 485 SMAGAALLAIVAIPILMGFWILGRIPAES----------SNPLNRFLIRiYHPLLLKVLHWPKTTLLIALLSILTVAWPL 554
Cdd:PRK10555 477 AMVLSVLVAMILTPALCATLLKPLKKGEHhgqkgffgwfNRMFNRNAER-YEKGVAKILHRSLRWILIYVLLLGGMVFLF 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 555 NRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPE--VARVFGKTGKAETATDSAPLEMVettIQLKP 632
Cdd:PRK10555 556 LRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKdnVMSVFATVGSGPGGNGQNVARMF---IRLKD 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 633 QDQwRPGMTMEK--IVEELDKTVRLPGLANLWV--PPIrnridmlSTGIKSPIGIKVSGTNLADI--DAIA---EQIEGV 703
Cdd:PRK10555 633 WDE-RDSKTGTSfaIIERATKAFNKIKEARVIAssPPA-------ISGLGSSAGFDMELQDHAGAghDALMaarNQLLAL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 704 ARSVPGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETvegVERYPINIRYPQS---YRDSP 780
Cdd:PRK10555 705 AAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDF---MDRGRVKKVYVQAaapYRMLP 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 781 ETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKevKLKPGISVSYSG 860
Cdd:PRK10555 782 DDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVK--QLPNGFGLEWTA 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 861 QfELLER-ANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAAE 939
Cdd:PRK10555 860 M-SYQERlSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAK 938
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 940 FGVVMLMYlrhaieaepslENPQTFSVDKLDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGG 1019
Cdd:PRK10555 939 NAILIVEF-----------ANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGG 1007
|
1050
....*....|...
gi 1031820593 1020 MITAPLLSLFIIP 1032
Cdd:PRK10555 1008 MISATILAIFFVP 1020
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
6-1049 |
1.98e-46 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 181.46 E-value: 1.98e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 6 IRRSVANRFLvmmaALFLSIWGTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVRGF 85
Cdd:PRK10614 8 IYRPVATILL----SLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 86 SQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSA-----EMGP-DATGVgwvfeyALVDRSGKHDLAELRSL 159
Cdd:PRK10614 84 SSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSrptyrKANPsDAPIM------ILTLTSDTYSQGQLYDF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 160 QDWFLKYELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYLQT 239
Cdd:PRK10614 158 ASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 240 LDDFKNIVLKTgDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAggVVILRS-GKNAREMISAVKEKLASLQSSLPEG 318
Cdd:PRK10614 238 AAEYQPLIIHY-NNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAIL--LMIRKLpEANIIQTVDRIRAKLPELRETIPAA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 319 VEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAI 398
Cdd:PRK10614 315 IDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 399 AVGAMVDAAIVMIENAHKRLEewEHQHPGEKLSNDTRwkiiteasvEVG-PALFISLLIITLsFIPIFTLEGQEGKLFGP 477
Cdd:PRK10614 395 ATGFVVDDAIVVLENISRHLE--AGMKPLQAALQGVR---------EVGfTVLSMSLSLVAV-FLPLLLMGGLPGRLFRE 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 478 LAFTKTWSMAGAALLAIVAIPiLMGFWILGRIPAESSNPL---NRFLIRI---YHPLLLKVLHWPKTTLLIALLSILTVA 551
Cdd:PRK10614 463 FAVTLSVAIGISLLVSLTLTP-MMCAWLLKSSKPREQKRLrgfGRMLVALqqgYGRSLKWVLNHTRWVGVVLLGTIALNV 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 552 WPLNRVGGEFLPQINEGDLLYMPSTLPGISAAQAADMLQKTDKLIMTVPEVARVFGKTGKAETATDSaplemveTTIQLK 631
Cdd:PRK10614 542 WLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGM-------MFITLK 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 632 PQDQwrPGMTMEKIVEEL-DKTVRLPGlANLWVPPIRnriDMLSTGIKSPIGIKVS--GTNLADIDAIAEQIEGVARSVP 708
Cdd:PRK10614 615 PLSE--RSETAQQVIDRLrVKLAKEPG-ANLFLMAVQ---DIRVGGRQSNASYQYTllSDDLAALREWEPKIRKALAALP 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 709 GVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYPQSYRDSPETLRQLPI 788
Cdd:PRK10614 689 ELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFV 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 789 LAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLERA 868
Cdd:PRK10614 769 INNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQET 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 869 NQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVatgtgfIALAGVAAEFGVV---ML 945
Cdd:PRK10614 849 MNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSL------IALIGIMLLIGIVkknAI 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 946 MYLRHAIEAEPSlenpqtfsvDKLD--EALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITA 1023
Cdd:PRK10614 923 MMVDFALEAQRN---------GNLTaqEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMS 993
|
1050 1060 1070
....*....|....*....|....*....|
gi 1031820593 1024 PLLSLFIIPAAY----KLMWLYRHRGKRSQ 1049
Cdd:PRK10614 994 QLLTLYTTPVVYlffdRLRLRFSRKPKQTV 1023
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
6-1049 |
1.65e-43 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 172.22 E-value: 1.65e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 6 IRRSVANRfLVMMAALFLSIWGTWTIvhtPVDALP--DLSDVQVIvkTRYPGQAPQIVENQVTWPLTTTMLSVPGAKTVR 83
Cdd:PRK10503 17 ILRPVATT-LLMVAILLAGIIGYRAL---PVSALPevDYPTIQVV--TLYPGASPDVMTSAVTAPLERQFGQMSGLKQMS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 84 GFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAG-----VSAEMGP-DATGVGWVFEYALVDRSGKHDLAELR 157
Cdd:PRK10503 91 SQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDlpnppVYSKVNPaDPPIMTLAVTSTAMPMTQVEDMVETR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 158 SLQdwflkyELKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISLGEVKSALDASNQEAGGSSVELAEAEYMVRASGYL 237
Cdd:PRK10503 171 VAQ------KISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 238 QTLDDFKNIVLkTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVViLRSGKNAREMISAVKEKLASLQSSLPE 317
Cdd:PRK10503 245 QSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQ-RQPGANIIATADSIRQMLPQLTESLPK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 318 GVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIA 397
Cdd:PRK10503 323 SVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALT 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 398 IAVGAMVDAAIVMIENAHKRLEEWEhqhpgeklsndtrwKIITEASVEVGPalfISLLIITLSF------IPIFTLEGQE 471
Cdd:PRK10503 403 IATGFVVDDAIVVIENISRYIEKGE--------------KPLAAALKGAGE---IGFTIISLTFsliavlIPLLFMGDIV 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 472 GKLFGPLAFTktwsMAGAALLAIVAIPILMGFWILGRIPAESSNPLNRF----------LIRIYHPLLLKVLHWPKTTLL 541
Cdd:PRK10503 466 GRLFREFAVT----LAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFsrasermfdrVIAAYGRGLAKVLNHPWLTLS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 542 IAL--LSILTVAWPLNRVGgeFLPQINEGDL---LYMPSTlpgISAAQAADMLQKTDKLIMTVPEVARV--FGKTGKAET 614
Cdd:PRK10503 542 VALstLLLTVLLWIFIPKG--FFPVQDNGIIqgtLQAPQS---SSFANMAQRQRQVADVILQDPAVQSLtsFVGVDGTNP 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 615 ATDSAPLEmvettIQLKPQDQwRPGMTMEKIVEELDKTVRLPGlANLWVPPIRN-RIDMLSTgiKSPIGIKVSGTNLADI 693
Cdd:PRK10503 617 SLNSARLQ-----INLKPLDE-RDDRVQKVIARLQTAVAKVPG-VDLYLQPTQDlTIDTQVS--RTQYQFTLQATSLDAL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 694 DAIAEQIEGVARSVPGVTSALAERLVGGRYLDIDIHREKAARYGMTVGDVQLFVSSAIGGAMVGETVEGVERYPINIRYP 773
Cdd:PRK10503 688 STWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHN 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 774 QSYRDSPETLRQLPILAPLKQQIVLGDVAEVKVVTGPSMLKTENARPTSWIYIDARD----RDMVSVVHDLQQAIGkevk 849
Cdd:PRK10503 768 TENTPGLAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDgyslGDAVQAIMDTEKTLN---- 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 850 LKPGISVSYSGQFELLERA-NQKLKLMVPMTLMIIFVL--LYLAFRrvgEALLIITSVPFALVGGIWFLYWMGFHLSVAT 926
Cdd:PRK10503 844 LPADITTQFQGSTLAFQSAlGSTVWLIVAAVVAMYIVLgvLYESFI---HPITILSTLPTAGVGALLALMIAGSELDVIA 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 927 GTGFIALAGVAAEFGVVMLMYlrhAIEAepslENPQTFSVdklDEALYRGAVLRVRPKAMTVAVIIAGLLPILWGTGAGS 1006
Cdd:PRK10503 921 IIGIILLIGIVKKNAIMMIDF---ALAA----EREQGMSP---RDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGA 990
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*.
gi 1031820593 1007 EVMSRIAAPMIGGMITAPLLSLFIIPAAYKL---MWLYRHRGKRSQ 1049
Cdd:PRK10503 991 ELRRPLGICMVGGLIVSQVLTLFTTPVIYLLfdrLALYTKSRFPRH 1036
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
830-1049 |
1.07e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 65.65 E-value: 1.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 830 DRDMVSVVHDLQQAIGKEVKlkPGISVSYSGQF----ELLERANQKLKLMVPMTLMIIFVLLYLAFRRVGEALLIITSVp 905
Cdd:COG1033 176 DLDRKEVVAEIRAIIAKYED--PGVEVYLTGFPvlrgDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVV- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 906 faLVGGIW---FLYWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLEnpqtfsvdkldEALYRgAVLRV- 981
Cdd:COG1033 253 --LLAVIWtlgLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKR-----------EALRE-ALRKLg 318
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1031820593 982 RPKAMTVAVIIAGLLPILWgtgAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAykLMWLYRHRGKRSQ 1049
Cdd:COG1033 319 PPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPAL--LSLLPRPKPKTRR 381
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
153-504 |
2.38e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 61.41 E-value: 2.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 153 LAELRSLQDWflkyeLKTIPNVSEVASVGGVVKEYQIVVDPMKLSQYGISlgevksaldasnqeaggSSVELAEAEYMVR 232
Cdd:COG1033 475 LKEIDRLQDY-----LESLPEVGKVLSLADLVKELNQALNEGDPKYYALP-----------------ESRELLAQLLLLL 532
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 233 ASGYLQTLDDFKNivlKTGDNG-VPVYLGDVarvqigpemrrgiaelngegevaggvvilrSGKNAREMISAVKEKLASL 311
Cdd:COG1033 533 SSPPGDDLSRFVD---EDYSAArVTVRLKDL------------------------------DSEEIKALVEEVRAFLAEN 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 312 QSslPEGVEV------VTTYDrsqLIDRAIDNLSYKLLEEFIVVALVCALFLWHVRSALVAIISLPLGLCFAFIMMHFQG 385
Cdd:COG1033 580 FP--PDGVEVtltgsaVLFAA---INESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLG 654
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 386 LNANIMSLGGIAIAVGAMVDAAIVMIEnahkRLEEwehqhpgEKLSNDTRWKIITEASVEVGPALFISLLIITLSFIpif 465
Cdd:COG1033 655 IPLNIATAVVASIALGIGVDYTIHFLS----RYRE-------ERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFG--- 720
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1031820593 466 TLegqegkLFGPLAFTK------TWSMAGAALLAIVAIPILMGFW 504
Cdd:COG1033 721 VL------LFSSFPPLAdfglllALGLLVALLAALLLLPALLLLL 759
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
827-1048 |
6.08e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 60.26 E-value: 6.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 827 DARDRDMVSVVHDLQQAIGKEVKLkPGISVSYSGQFELLERANQKL----KLMVPMTLMIIFVLLYLAFRRVGEALLIIT 902
Cdd:COG1033 559 DLDSEEIKALVEEVRAFLAENFPP-DGVEVTLTGSAVLFAAINESViesqIRSLLLALLLIFLLLLLAFRSLRLGLISLI 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 903 SVPFALVGGIWFLYWMGFHLSVATGTGF-IALaGVAAEFGVVMLMYLRHAIEAEPSLEnpqtfsvdkldEALYRgaVLRV 981
Cdd:COG1033 638 PNLLPILLTFGLMGLLGIPLNIATAVVAsIAL-GIGVDYTIHFLSRYREERRKGGDLE-----------EAIRR--ALRT 703
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1031820593 982 RPKAMTV--AVIIAGLLPILWgtgAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAykLMWLYRHRGKRS 1048
Cdd:COG1033 704 TGKAILFtsLTLAAGFGVLLF---SSFPPLADFGLLLALGLLVALLAALLLLPAL--LLLLDPRIAKKR 767
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
770-1037 |
2.85e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.84 E-value: 2.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 770 IRYPQSYRDSPETLRQLPILAPLKQqivlgDVAEVKVVTgpSMLKTENAR-----PTSWIYI-----DARDRDMVSVVHD 839
Cdd:TIGR00921 87 KPYVTNVRSAADIMRQIPGNFPLPV-----TMPEVRPLM--SEYPRSKEMflskdHTVAIIIvqlksDADYKQVVPIYND 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 840 LQQAI-------GKEVKLKPGISVSYsgQFELLERANQKLKLMVPMTLMIifVLLYLAFRRVGEALLIITSVPFALVGGI 912
Cdd:TIGR00921 160 VERSLertnppsGKFLDVTGSPAINY--DIEREFGKDMGTTMAISGILVV--LVLLLDFKRWWRPLLPLVIILFGVAWVL 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 913 WFLYWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLEnpqtfsvDKLDEALYRGAVLRVRPKAMTVAVII 992
Cdd:TIGR00921 236 GIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKG-------EAIVTAVRRTGRAVLIALLTTSAGFA 308
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1031820593 993 AGLLPILwgtgagsEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1037
Cdd:TIGR00921 309 ALALSEF-------PMVSEFGLGLVAGLITAYLLTLLVLPALLQS 346
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
6-500 |
2.85e-04 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 44.89 E-value: 2.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 6 IRRSVAnRFLVMMAALFLSIwgTWTIVHTPVDALPDLSDVQVIVKTRYPGQAPQ----IVENQVT-WPLTTTMLSVPGAK 80
Cdd:PRK15127 534 ILRSTG-RYLVLYLIIVVGM--AYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQertqKVLNEVTdYYLTKEKNNVESVF 610
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 81 TVRGFSQFG----DSYVYVIFEDGTDPYWARSRV-------LEYLNQVQG------KLPAGVsaEMGpDATGvgwvFEYA 143
Cdd:PRK15127 611 AVNGFGFAGrgqnTGIAFVSLKDWADRPGEENKVeaitmraTRAFSQIKDamvfafNLPAIV--ELG-TATG----FDFE 683
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 144 LVDRSG-KHD-LAELRSLqdwfLKYELKTIPNVSEVASVGGV--VKEYQIVVDPMKLSQYGISLGEVKSALDASnqeAGG 219
Cdd:PRK15127 684 LIDQAGlGHEkLTQARNQ----LLGEAAKHPDMLVGVRPNGLedTPQFKIDIDQEKAQALGVSISDINTTLGAA---WGG 756
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 220 SSVE------LAEAEYMVRASGYLQTLDDFKNIVLKtGDNG--VPVYLGDVARVQIG-PEMRR--GIAELNGEGEVAggv 288
Cdd:PRK15127 757 SYVNdfidrgRVKKVYVMSEAKYRMLPDDIGDWYVR-AADGqmVPFSAFSSSRWEYGsPRLERynGLPSMEILGQAA--- 832
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 289 vilrSGKNAREMISAVKEklasLQSSLPEGVevvtTYDRSQLI--DRAIDNLSYKLLEEFIVVALVCALFLWHVRS-ALV 365
Cdd:PRK15127 833 ----PGKSTGEAMELMEE----LASKLPTGV----GYDWTGMSyqERLSGNQAPALYAISLIVVFLCLAALYESWSiPFS 900
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 366 AIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAhKRLEEWEHqhpgeklsndtrwKIITEASVE 445
Cdd:PRK15127 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFA-KDLMDKEG-------------KGLIEATLE 966
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1031820593 446 VGPALFISLLIITLSFI-PIFTLEGQEGKLFGPLAFTKTWSMAG---AALLAIVAIPIL 500
Cdd:PRK15127 967 AVRMRLRPILMTSLAFIlGVMPLVISSGAGSGAQNAVGTGVMGGmvtATVLAIFFVPVF 1025
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
836-1048 |
3.31e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 44.84 E-value: 3.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 836 VVHDLQQAIGKEVKLKPGISVSYSGQFELLERANQKLK----LMVPMTLMIIFVLLYLAFRRVGEALLIITSVPFALVGG 911
Cdd:COG4258 211 LVAALRAAFAALNAAFPGAQLLLTGAGLFAVAAAQQIKhdisTIGLISLLGILLLLLLVFRSLRPLLLGLLPVAVGALAG 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 912 IWFLYWmGF-HLSVAT-GTGFiALAGVAAEFGVVMLMYLRHAIEAEPslenpqtfsvdkldEALYRgavlRVRPkAMTVA 989
Cdd:COG4258 291 LAAVSL-VFgSVHGITlGFGS-SLIGVAVDYSLHYLTHRRAAGEWDP--------------RAALR----RIWP-TLLLG 349
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1031820593 990 VI--IAGLLPILWgtgAGSEVMSRIAAPMIGGMITAPLLSLFIIPaayklmWLYRHRGKRS 1048
Cdd:COG4258 350 LLttVLGYLALLF---SPFPGLRQLGVFAAAGLLAAALTTLLWLP------LLLPRAAPRP 401
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
288-501 |
7.27e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 40.21 E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 288 VVILRSGKNAREMISAVKEKLASLQ-SSLPEGVEVVTTYDRSqlidraidnLSYKLLEEF------------IVVALVCA 354
Cdd:TIGR00921 141 IVQLKSDADYKQVVPIYNDVERSLErTNPPSGKFLDVTGSPA---------INYDIEREFgkdmgttmaisgILVVLVLL 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 355 LFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMVDAAIvmieNAHKRLEewEHQHPGEKLSndt 434
Cdd:TIGR00921 212 LDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGI----QTLNRYE--EERDIGRAKG--- 282
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031820593 435 rwKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEGKLFGPLaftktwSMAG---AALLAIVAIPILM 501
Cdd:TIGR00921 283 --EAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLG------LVAGlitAYLLTLLVLPALL 344
|
|
| |
