|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
2-361 |
5.51e-87 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 266.77 E-value: 5.51e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 2 KILFSASVYRHLAAFHIPYMQYFLNNGHEVYAVAKDDGNKNV-IENLGVKCIDIDIER-SPFKLSNIKAYFQLKSILRIN 79
Cdd:cd03808 1 KILFIVNVDGGFQSFRLPLIKALVKKGYEVHVIAPDGDKLSDeLKELGVKVIDIPILRrGINPLKDLKALFKLYKLLKKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 80 NFDLITTHTPFISFLIRLVN--LNHTKLIYTAHGFHFYKGGSVVKNTLYKNMERFAAKFTDEIAVMNEEDYKSAQQ--FF 155
Cdd:cd03808 81 KPDIVHCHTPKPGILGRLAArlAGVPKVIYTVHGLGFVFTEGKLLRLLYLLLEKLALLFTDKVIFVNEDDRDLAIKkgII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 156 NKENVHFINGIGVNLSEYNAVNIDnhtsireelgLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGE 235
Cdd:cd03808 161 KKKKTVLIPGSGVDLDRFQYSPES----------LPSEKVVFLFVARLLKDKGIDELIEAAKILKKKGPNVRFLLVGDGE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 236 MGEVYKEYVANHNLEGVI-FAGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFT 314
Cdd:cd03808 231 LENPSEILIEKLGLEGRIeFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGVNGFL 310
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1032578817 315 IELDNDEELIDKFITLIQNKNLRHNMGLNNEQI-KERYSETTVLEQMK 361
Cdd:cd03808 311 VPPGDVEALADAIEKLIEDPELRKEMGEAARKRvEEKFDEEKVVNKLL 358
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
2-360 |
2.35e-46 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 161.94 E-value: 2.35e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 2 KILFSASVYRHLAAFHIPYMQYFLN----NGHEVYAVAKDDGNKNVIENlgvkcIDIDIERSPFKLSNIKAYF----QLK 73
Cdd:cd03801 1 KILLLSPELPPPVGGAERHVRELARalaaRGHDVTVLTPADPGEPPEEL-----EDGVIVPLLPSLAALLRARrllrELR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 74 SILRINNFDLITTHTPFISFLIRLV-NLNHTKLIYTAHGFHFYkggsvVKNTLYKNMERFAAK------FTDEIAVMNEE 146
Cdd:cd03801 76 PLLRLRKFDVVHAHGLLAALLAALLaLLLGAPLVVTLHGAEPG-----RLLLLLAAERRLLARaeallrRADAVIAVSEA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 147 DYKSAQQFFN--KENVHFIngigvnlseYNAVNIDN-HTSIREELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKC 223
Cdd:cd03801 151 LRDELRALGGipPEKIVVI---------PNGVDLERfSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRRG 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 224 PRAKLVLIGS-GEMGEVYKEYVANhNLEGVIFAGYR--QDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIR 300
Cdd:cd03801 222 PDVRLVIVGGdGPLRAELEELELG-LGDRVRFLGFVpdEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVG 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1032578817 301 GNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLNN-EQIKERYSETTVLEQM 360
Cdd:cd03801 301 GLPEVVEDGEGGLVVPPDDVEALADALLRLLADPELRARLGRAArERVAERFSWERVAERL 361
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
20-353 |
1.76e-34 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 130.17 E-value: 1.76e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 20 YMQYFLNNGHEV-YAVAKDDGNKNVIENLGVKCIDIDIERSPF-KLSNIKAYFQLKSILRINNFDLITTHTPFISFLIRL 97
Cdd:cd03811 21 LANALDKRGYDVtLVLLRDEGDLDKQLNGDVKLIRLLIRVLKLiKLGLLKAILKLKRILKRAKPDVVISFLGFATYIVAK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 98 VNLNHTKLIYTAHGFHFYKGGSVVKNTLYKNMERFAAKF---TDEIAvmneedyKSAQQFF--NKENVHFIngigvnlse 172
Cdd:cd03811 101 LAAARSKVIAWIHSSLSKLYYLKKKLLLKLKLYKKADKIvcvSKGIK-------EDLIRLGpsPPEKIEVI--------- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 173 YNAVNIDNHTSIREELGLDSND--IIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNLE 250
Cdd:cd03811 165 YNPIDIDRIRALAKEPILNEPEdgPVILAVGRLDPQKGHDLLIEAFAKLRKKYPDVKLVILGDGPLREELEKLAKELGLA 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 251 G-VIFAGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFIT 329
Cdd:cd03811 245 ErVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGENGLLVPDGDAAALAGILAA 324
|
330 340
....*....|....*....|....*..
gi 1032578817 330 LIQNKN---LRHNMGLNNEQIKERYSE 353
Cdd:cd03811 325 LLQKKLdaaLRERLAKAQEAVFREYTI 351
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
23-359 |
5.95e-33 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 125.81 E-value: 5.95e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 23 YFLNNGHEVYAVAKDDGNKNV---------IENLGvkciDIDIERSPFKLSNIKAYFQLKSILRINNFD-LITTHTPFIS 92
Cdd:cd03820 25 HLAKKGYDVTIISLDSAEKPPfyelddnikIKNLG----DRKYSHFKLLLKYFKKVRRLRKYLKNNKPDvVISFRTSLLT 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 93 FLIrLVNLNhTKLIYTAHgFHFYKGGSVVKNTLyknMERFAAKFTDEIAVMNEEDYKSAQQFFNKeNVHFIngigvnlse 172
Cdd:cd03820 101 FLA-LIGLK-SKLIVWEH-NNYEAYNKGLRRLL---LRRLLYKRADKIVVLTEADKLKKYKQPNS-NVVVI--------- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 173 YNAVNIDNHtsiREELGLDSNDIIisYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNLEG- 251
Cdd:cd03820 165 PNPLSFPSE---EPSTNLKSKRIL--AVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYGDGPEREELEKLIDKLGLEDr 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 252 VIFAGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIR-GNTDLVQNGINGFTIELDNDEELIDKFITL 330
Cdd:cd03820 240 VKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPtGPSEIIEDGENGLLVPNGDVDALAEALLRL 319
|
330 340
....*....|....*....|....*....
gi 1032578817 331 IQNKNLRHNMGLNNEQIKERYSETTVLEQ 359
Cdd:cd03820 320 MEDEELRKKMGKNARKNAERFSIEKIIKQ 348
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
196-333 |
3.87e-29 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 109.52 E-value: 3.87e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 196 IISYVAEMSKR-KNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVyKEYVANHNlEGVIFAGYRQDIKEIIYQSDIVALL 274
Cdd:pfam13692 3 VILFVGRLHPNvKGVDYLLEAVPLLRKRDNDVRLVIVGDGPEEEL-EELAAGLE-DRVIFTGFVEDLAELLAAADVFVLP 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1032578817 275 STQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQnGINGFTIELDNDEELIDKFITLIQN 333
Cdd:pfam13692 81 SLYEGFGLKLLEAMAAGLPVVATDVGGIPELVD-GENGLLVPPGDPEALAEAILRLLED 138
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
28-367 |
1.30e-28 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 114.30 E-value: 1.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 28 GHEVYAVA-KDDGNKNVIENLGVKCIDIDIERSP---FKLSNIKAYfqlKSILRINNFDLITTHTPFISFLIRL------ 97
Cdd:cd03817 31 GHEVYVITpSDPGAEDEEEVVRYRSFSIPIRKYHrqhIPFPFKKAV---IDRIKELGPDIIHTHTPFSLGKLGLriarkl 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 98 ----VNLNHTKLiytAHGFHFYKGGSVVKNTLYKNMERFAAKFTDEIAVMNEEDYKSAQQFFNKENVHFI-NGIgvNLSE 172
Cdd:cd03817 108 kipiVHTYHTMY---EDYLHYIPKGKLLVKAVVRKLVRRFYNHTDAVIAPSEKIKDTLREYGVKGPIEVIpNGI--DLDK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 173 YNAVNIdnhTSIREELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKcPRAKLVLIGSGEMGEVYKEYVANHNL-EG 251
Cdd:cd03817 183 FEKPLN---TEERRKLGLPPDEPILLYVGRLAKEKNIDFLLRAFAELKKE-PNIKLVIVGDGPEREELKELARELGLaDK 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 252 VIFAGY--RQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIElDNDEELIDKFIT 329
Cdd:cd03817 259 VIFTGFvpREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAASELVEDGENGFLFE-PNDETLAEKLLH 337
|
330 340 350
....*....|....*....|....*....|....*...
gi 1032578817 330 LIQNKNLRHNMGLNNEQIKERYSettVLEQMKCIYDKV 367
Cdd:cd03817 338 LRENLELLRKLSKNAEISAREFA---FAKSVEKLYEEV 372
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
193-346 |
1.35e-28 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 108.90 E-value: 1.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 193 NDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNL-EGVIFAGY--RQDIKEIIYQSD 269
Cdd:pfam00534 1 KKKIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLgDNVIFLGFvsDEDLPELLKIAD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1032578817 270 IVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLNNEQ 346
Cdd:pfam00534 81 VFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
29-352 |
8.60e-27 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 109.33 E-value: 8.60e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 29 HEVYAVAKDDGNKNVIENLGVK--CIDIDIERSPFKLsnikayFQLKSILRINNFDLITTHTP---FISFLIRLVNLNhT 103
Cdd:cd03807 32 HVVISLTGDGVLGEELLAAGVPvvCLGLSSGKDPGVL------LRLAKLIRKRNPDVVHTWMYhadLIGGLAAKLAGG-V 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 104 KLIYTAHGFHFYKGGSVVKNTLYKNMERFaakFTDEIAVMNEEDYKSAQQFFNKENVHFI-NGIgvNLSEYNavnIDNH- 181
Cdd:cd03807 105 KVIWSVRSSNIPQRLTRLVRKLCLLLSKF---SPATVANSSAVAEFHQEQGYAKNKIVVIyNGI--DLFKLS---PDDAs 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 182 -TSIREELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNLEG-VIFAGYRQ 259
Cdd:cd03807 177 rARARRRLGLAEDRRVIGIVGRLHPVKDHSDLLRAAALLVETHPDLRLLLVGRGPERPNLERLLLELGLEDrVHLLGERS 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 260 DIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGiNGFTIELDNDEELIDKFITLIQNKNLRHN 339
Cdd:cd03807 257 DVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELVDDG-TGFLVPAGDPQALADAIRALLEDPEKRAR 335
|
330
....*....|....
gi 1032578817 340 MGLN-NEQIKERYS 352
Cdd:cd03807 336 LGRAaRERIANEFS 349
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
36-366 |
8.12e-22 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 95.20 E-value: 8.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 36 KDDGNKNVIENLGvkcididIERSPFKLsnIKAYFQLKSILRINNFDLITTHTPFISFLIRL--VNLNHTKLIYTAHGFH 113
Cdd:cd04951 44 KPLNNNIIIYNLG-------MDKNPRSL--LKALLKLKKIISAFKPDVVHSHMFHANIFARFlrMLYPIPLLICTAHNKN 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 114 FykgGSVVKNTLYKNMERFAAKFTDeiaVMNEE-DYKSAQQFFNK-ENVHFINGIGVNLSEYNAVNIDNhtsIREELGLD 191
Cdd:cd04951 115 E---GGRIRMFIYRLTDFLCDITTN---VSREAlDEFIAKKAFSKnKSVPVYNGIDLNKFKKDINVRLK---IRNKLNLK 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 192 SNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNL-EGVIFAGYRQDIKEIIYQSDI 270
Cdd:cd04951 186 NDEFVILNVGRLTEAKDYPNLLLAISELILSKNDFKLLIAGDGPLRNELERLICNLNLvDRVILLGQISNISEYYNAADL 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 271 VALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNgiNGFTIELDNDEELIDKFI-TLIQNKNLRHNMGLNNEQIKE 349
Cdd:cd04951 266 FVLSSEWEGFGLVVAEAMACERPVVATDAGGVAEVVGD--HNYVVPVSDPQLLAEKIKeIFDMSDEERDILGNKNEYIAK 343
|
330
....*....|....*..
gi 1032578817 350 RYSETTVLEQMKCIYDK 366
Cdd:cd04951 344 NFSINTIVNEWERLYSG 360
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
22-352 |
1.35e-21 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 95.10 E-value: 1.35e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 22 QYFLNNGHEVYAVA---------KDDGNKNVIENLGVKCIDIDIERSPFKLSNIKAYFQ------LKSILRINNFDLITT 86
Cdd:cd03794 25 KELVRRGHEVTVLTpspnyplgrIFAGATETKDGIRVIRVKLGPIKKNGLIRRLLNYLSfalaalLKLLVREERPDVIIA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 87 HTPFISFLI---RLVNLNHTKLIYTAHGFH--------FYKGGSVVKntLYKNMERFAAKFTDEIAVMNEEDYKS-AQQF 154
Cdd:cd03794 105 YSPPITLGLaalLLKKLRGAPFILDVRDLWpeslialgVLKKGSLLK--LLKKLERKLYRLADAIIVLSPGLKEYlLRKG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 155 FNKENVHFINgIGVNLSEYNAVNIDNhtsIREELGLDsNDIIISYVAEMSKRKNQLYLLKNWKKITyKCPRAKLVLIGSG 234
Cdd:cd03794 183 VPKEKIIVIP-NWADLEEFKPPPKDE---LRKKLGLD-DKFVVVYAGNIGKAQGLETLLEAAERLK-RRPDIRFLFVGDG 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 235 EMGEVYKEYVANHNLEGVIFAGY--RQDIKEIIYQSDiVALLS------TQEGLPRCVLEGMALHKPLIVSHIRGNTDLV 306
Cdd:cd03794 257 DEKERLKELAKARGLDNVTFLGRvpKEEVPELLSAAD-VGLVPlkdnpaNRGSSPSKLFEYMAAGKPILASDDGGSDLAV 335
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1032578817 307 QNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLN-NEQIKERYS 352
Cdd:cd03794 336 EINGCGLVVEPGDPEALADAILELLDDPELRRAMGENgRELAEEKFS 382
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
31-337 |
4.69e-21 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 93.12 E-value: 4.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 31 VYAVAKDDGN-KNVIENLGVKCIDIDIERSpfklSNIKAYFQLKSILRINNFDLITTHTPFISFLIRLV--NLNHTKLIY 107
Cdd:cd03812 34 FLATSDDKGEyDEELEELGGKIFYIPPKKK----NIIKYFIKLLKLIKKEKYDIVHVHGSSSNGIILLLaaKAGVPVRIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 108 TAH----GFHFYKggSVVKNTLYKNMERFAakfTDEIAVmNEEDYKSAQQFFNKENVHFI-NGIGVNLSEYNAVNIDNht 182
Cdd:cd03812 110 HSHntkdSSIKLR--KIRKNVLKKLIERLS---TKYLAC-SEDAGEWLFGEVENGKFKVIpNGIDIEKYKFNKEKRRK-- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 183 siREELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNLEG-VIFAGYRQDI 261
Cdd:cd03812 182 --RRKLLILEDKLVLGHVGRFNEQKNHSFLIDIFEELKKKNPNVKLVLVGEGELKEKIKEKVKELGLEDkVIFLGFRNDV 259
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1032578817 262 KEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIElDNDEELIDKFITLIQNKNLR 337
Cdd:cd03812 260 SEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTITKECDITNNVEFLPLN-ETPSTWAEKILKLIKRKRRI 334
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
261-369 |
5.05e-20 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 84.66 E-value: 5.05e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 261 IKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNM 340
Cdd:COG0438 14 LEALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRL 93
|
90 100 110
....*....|....*....|....*....|
gi 1032578817 341 GLNN-EQIKERYSETTVLEQMKCIYDKVLS 369
Cdd:COG0438 94 GEAArERAEERFSWEAIAERLLALYEELLA 123
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
27-337 |
2.60e-19 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 87.80 E-value: 2.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 27 NGHEVYaVAKDDGNknvienlGVKCIDIDIERSPFKLSNI----KAYFQLKSILRINNFDLITTHTPFISFLIRLV-NLN 101
Cdd:cd03819 27 RGHRVL-VVTAGGP-------LLPRLRQIGIGLPGLKVPLlralLGNVRLARLIRRERIDLIHAHSRAPAWLGWLAsRLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 102 HTKLIYTAHGFHFykggsvvkntLYKNMERFAA---KFTDE-IAV-MNEEDYKSAQQFFNKENVHFIngigvnlseYNAV 176
Cdd:cd03819 99 GVPLVTTVHGSYL----------ATYHPKDFALavrARGDRvIAVsELVRDHLIEALGVDPERIRVI---------PNGV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 177 NIDNHT-----SIREELGLDSNDIIISYVAEMSKRKNQLYLLK---NWKKItykcPRAKLVLIGSGEMGEVYKEYVANHN 248
Cdd:cd03819 160 DTDRFPpeaeaEERAQLGLPEGKPVVGYVGRLSPEKGWLLLVDaaaELKDE----PDFRLLVAGDGPERDEIRRLVERLG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 249 LEG-VIFAGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKF 327
Cdd:cd03819 236 LRDrVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLLVPPGDAEALADAI 315
|
330
....*....|
gi 1032578817 328 ITLIQNKNLR 337
Cdd:cd03819 316 RAAKLLPEAR 325
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
72-367 |
8.45e-19 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 86.66 E-value: 8.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 72 LKSILRINN--FDLITTH----TPFISflIRLVNLNHTKLIYTAHGFHFYKG--GSVVKNTLYKNMERFAAkftdEIAV- 142
Cdd:cd03798 85 AKLLKRRRRgpPDLIHAHfaypAGFAA--ALLARLYGVPYVVTEHGSDINVFppRSLLRKLLRWALRRAAR----VIAVs 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 143 --MNEEdykSAQQFFNKENVHFINgIGVNLSEYNAVNidnhtsirEELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKIT 220
Cdd:cd03798 159 kaLAEE---LVALGVPRDRVDVIP-NGVDPARFQPED--------RGLGLPLDAFVILFVGRLIPRKGIDLLLEAFARLA 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 221 YKCPRAKLVLIGSGEMGEVYKEYVANHNLE-GVIFAGY--RQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVS 297
Cdd:cd03798 227 KARPDVVLLIVGDGPLREALRALAEDLGLGdRVTFTGRlpHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVAT 306
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 298 HIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLNNEQIKERYSETTVLEQMKCIYDKV 367
Cdd:cd03798 307 DVGGIPEVVGDPETGLLVPPGDADALAAALRRALAEPYLRELGEAARARVAERFSWVKAADRIAAAYRDV 376
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
178-359 |
1.20e-16 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 80.04 E-value: 1.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 178 IDNHTSIREELGLDSNDIIisYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNLEG-VIFAG 256
Cdd:cd04949 146 VDQLDTAESNHERKSNKII--TISRLAPEKQLDHLIEAVAKAVKKVPEITLDIYGYGEEREKLKKLIEELHLEDnVFLKG 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 257 YRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIR-GNTDLVQNGINGFTIELDNDEELIDKFITLIQNKN 335
Cdd:cd04949 224 YHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKyGPSELIEDGENGYLIEKNNIDALADKIIELLNDPE 303
|
170 180
....*....|....*....|....
gi 1032578817 336 LRHNMGLNNEQIKERYSETTVLEQ 359
Cdd:cd04949 304 KLQQFSEESYKIAEKYSTENVMEK 327
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
28-360 |
1.41e-15 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 77.02 E-value: 1.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 28 GHEVYAVAKDDGNKNVIEN-LGVKCIDID-IERSPFKLSNIKAY---FQLKSILRIN--NFDLITTH---TPFISFLIRL 97
Cdd:cd03821 31 GHEVTIVSTGDGYESLVVEeNGRYIPPQDgFASIPLLRQGAGRTdfsPGLPNWLRRNlrEYDVVHIHgvwTYTSLAACKL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 98 VNLNHTKLIYTAHGF--HFYKGGSVVKNTLYKNM-ERFAAKFTDEIAVMNEEDYKsAQQFFNKENVHFINGIGVNLSEYN 174
Cdd:cd03821 111 ARRRGIPYVVSPHGMldPWALQQKHWKKRIALHLiERRNLNNAALVHFTSEQEAD-ELRRFGLEPPIAVIPNGVDIPEFD 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 175 AVNIDnhtsiREELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYK-EYVANHNLE--- 250
Cdd:cd03821 190 PGLRD-----RRKHNGLEDRRIILFLGRIHPKKGLDLLIRAARKLAEQGRDWHLVIAGPDDGAYPAFlQLQSSLGLGdrv 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 251 ---GVIFagyrQDIKEIIYQS-DIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIelDNDEELIDK 326
Cdd:cd03821 265 tftGPLY----GEAKWALYASaDLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELVEAGCGVVVD--PNVSSLAEA 338
|
330 340 350
....*....|....*....|....*....|....*..
gi 1032578817 327 FITLIQNKNLRHNMGLNNE---QIKERYSETTVLEQM 360
Cdd:cd03821 339 LAEALRDPADRKRLGEMARrarQVEENFSWEAVAGQL 375
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
199-315 |
2.58e-15 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 74.75 E-value: 2.58e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 199 YVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVAN----HNLEGVIFAGYRQDIKEIIYQSDIVALL 274
Cdd:cd01635 115 SVGRLVPEKGIDLLLEALALLKARLPDLVLVLVGGGGEREEEEALAAAlgllERVVIIGGLVDDEVLELLLAAADVFVLP 194
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1032578817 275 STQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTI 315
Cdd:cd01635 195 SRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGENGLLV 235
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
173-365 |
4.58e-14 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 73.14 E-value: 4.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 173 YNAVNIDNHTSIREELGlDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVY----KEYVANHN 248
Cdd:cd03813 273 PNGIDIQRFAPAREERP-EKEPPVVGLVGRVVPIKDVKTFIRAFKLVRRAMPDAEGWLIGPEDEDPEYaqecKRLVASLG 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 249 LEG-VIFAGyRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGIN-----GFTIELDNDEE 322
Cdd:cd03813 352 LENkVKFLG-FQNIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDVGSCRELIYGADDalgqaGLVVPPADPEA 430
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1032578817 323 LIDKFITLIQNKNLRHNMGLNNEQIKER-YSETTVLEQMKCIYD 365
Cdd:cd03813 431 LAEALIKLLRDPELRQAFGEAGRKRVEKyYTLEGMIDSYRKLYL 474
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
185-367 |
2.55e-12 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 67.38 E-value: 2.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 185 REELGLDSNDIIIsYVAEMSKRKNQLYLLKNWKKITYKCPrAKLVLIGSGEMGEVYKEYVANHNLEG-VIFAGYRQDIKE 263
Cdd:cd04962 188 RRLLAPPDEKVVI-HVSNFRPVKRIDDVVRVFARVRRKIP-AKLLLVGDGPERVPAEELARELGVEDrVLFLGKQDDVEE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 264 IIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLN 343
Cdd:cd04962 266 LLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEVVKHGETGFLSDVGDVDAMAKSALSILEDDELYNRMGRA 345
|
170 180
....*....|....*....|....*
gi 1032578817 344 N-EQIKERYSETTVLEQMKCIYDKV 367
Cdd:cd04962 346 ArKRAAERFDPERIVPQYEAYYRRL 370
|
|
| Glyco_trans_4_2 |
pfam13477 |
Glycosyl transferase 4-like; |
2-144 |
1.40e-11 |
|
Glycosyl transferase 4-like;
Pssm-ID: 433241 [Multi-domain] Cd Length: 139 Bit Score: 61.57 E-value: 1.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 2 KILFSASvyrhLAAFH-IPYMQYFLNNGHEVYAVAKDDGNKNVIENLGVKCIDIDIERSpFKLSNIKAyFQLKSILRINN 80
Cdd:pfam13477 1 KILLLAN----ADSIHtLRWADALADRGYDVHVISSKGPAKDELIAEGIHVHRLKVPRK-GPLGYLKA-FRLKKLIKKIK 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1032578817 81 FDLITTHTP-----FISFLIRLvnLNHTKLIYTAHGFHFYKGGSvvKNTLYKNMERFAAKFTDEIAVMN 144
Cdd:pfam13477 75 PDVVHVHYAkpyglLAGLAARL--SGFPPVVLSAWGLDVYKFPN--KSRLKKLLLKLNLKKATLIISTS 139
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
173-340 |
4.55e-11 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 63.54 E-value: 4.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 173 YNAVNIDNHTSIREE----LGLDSNDIIIsYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSG--EMGEVYKEYVAN 246
Cdd:cd03809 168 PLGVDPSFFPPESAAvliaKYLLPEPYFL-YVGTLEPRKNHERLLKAFALLKKQGGDLKLVIVGGKgwEDEELLDLVKKL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 247 HNLEGVIFAGY--RQDIKEIIYQSDIVALLSTQE--GLPrcVLEGMALHKPLIVSHIrgntdLV---QNGINGFTIELDN 319
Cdd:cd03809 247 GLGGRVRFLGYvsDEDLPALYRGARAFVFPSLYEgfGLP--VLEAMACGTPVIASNI-----SVlpeVAGDAALYFDPLD 319
|
170 180
....*....|....*....|.
gi 1032578817 320 DEELIDKFITLIQNKNLRHNM 340
Cdd:cd03809 320 PESIADAILRLLEDPSLREEL 340
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
167-360 |
4.55e-11 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 63.80 E-value: 4.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 167 GVNLSEYNAVniDNHTSIREELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIG--SGEMG----EVY 240
Cdd:cd03800 195 GVDLERFFPV--DRAEARRARLLLPPDKPVVLALGRLDPRKGIDTLVRAFAQLPELRELANLVLVGgpSDDPLsmdrEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 241 KEYVANHNLEG-VIFAGY--RQDIKEIIYQSDIVALLSTQE--GLprCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTI 315
Cdd:cd03800 273 AELAEELGLIDrVRFPGRvsRDDLPELYRAADVFVVPSLYEpfGL--TAIEAMACGTPVVATAVGGLQDIVRDGRTGLLV 350
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1032578817 316 ELDNDEELIDKFITLIQNKNLRHNMGLNN-EQIKERYSETTVLEQM 360
Cdd:cd03800 351 DPHDPEALAAALRRLLDDPALWQRLSRAGlERARAHYTWESVADQL 396
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
40-361 |
6.11e-10 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 59.98 E-value: 6.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 40 NKNVIENLGVKCI-----DIDIERSPFKLSNIKayfQLKSIlrINNFDLITTHTPF-----ISFLIRLvnlnHTKLIYTA 109
Cdd:cd03795 43 KETPEKEENGIRIhrvksFLNVASTPFSPSYIK---RFKKL--AKEYDIIHYHFPNpladlLLFFSGA----KKPVVVHW 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 110 HGfhfykggSVVKNT----LYKNMERFAAKFTDEIAVMNEEDYKSAQQFFN-KENVHFINgIGVNLSEYNAVNIDNHTSI 184
Cdd:cd03795 114 HS-------DIVKQKkllkLYKPLMTRFLRRADRIIATSPNYVETSPTLREfKNKVRVIP-LGIDKNVYNIPRVDFENIK 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 185 REELGldsnDIIISYVAEMSKRKNQLYLLKNWKKItyKCPrakLVLIGSGEMGEVYKEYVANHNLEGVIFAGYRQDIKEI 264
Cdd:cd03795 186 REKKG----KKIFLFIGRLVYYKGLDYLIEAAQYL--NYP---IVIGGEGPLKPDLEAQIELNLLDNVKFLGRVDDEEKV 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 265 IY--QSDIVALLST--QEGLPRCVLEGMALHKPLIVSHI-RGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHN 339
Cdd:cd03795 257 IYlhLCDVFVFPSVlrSEAFGIVLLEAMMCGKPVISTNIgTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRES 336
|
330 340
....*....|....*....|..
gi 1032578817 340 MGLNneqIKERYSETTVLEQMK 361
Cdd:cd03795 337 YGEN---AKKRFEELFTAEKMK 355
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
195-351 |
1.24e-08 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 55.92 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 195 IIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNLEGVI-FAGYRQ--DIKEIIYQSDIV 271
Cdd:cd03799 175 IRILTVGRLTEKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDLKEQLQQLIQELNIGDCVkLLGWKPqeEIIEILDEADIF 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 272 ALLST------QEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGL-NN 344
Cdd:cd03799 255 IAPSVtaadgdQDGPPNTLKEAMAMGLPVISTEHGGIPELVEDGVSGFLVPERDAEAIAEKLTYLIEHPAIWPEMGKaGR 334
|
....*..
gi 1032578817 345 EQIKERY 351
Cdd:cd03799 335 ARVEEEY 341
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
180-346 |
6.16e-08 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 53.86 E-value: 6.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 180 NHTSIREELGLDSNDI----IISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSG-----EMGEVYKEYVANHNLE 250
Cdd:cd03792 179 SPADIRYYLEKPFVIDperpYILQVARFDPSKDPLGVIDAYKLFKRRAEEPQLVICGHGavddpEGSVVYEEVMEYAGDD 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 251 GVIF----AGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIelDNDEELIDK 326
Cdd:cd03792 259 HDIHvlrlPPSDQEINALQRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGFLV--NSVEGAAVR 336
|
170 180
....*....|....*....|
gi 1032578817 327 FITLIQNKNLRHNMGLNNEQ 346
Cdd:cd03792 337 ILRLLTDPELRRKMGLAARE 356
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
222-364 |
6.36e-08 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 53.87 E-value: 6.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 222 KCPRAKLVLIGSGEMGEvyKEYVANHNLEGVIFAG-YRQDIKEIIYQS-DIVALLST-QEGLPRCVLEGMALHKPLIVSH 298
Cdd:cd03823 215 RLPREDIELVIAGHGPL--SDERQIEGGRRIAFLGrVPTDDIKDFYEKiDVLVVPSIwPEPFGLVVREAIAAGLPVIASD 292
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1032578817 299 IRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGlnnEQIKERYSETTVLEQMKCIY 364
Cdd:cd03823 293 LGGIAELIQPGVNGLLFAPGDAEDLAAAMRRLLTDPALLERLR---AGAEPPRSTESQAEEYLKLY 355
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
183-365 |
1.62e-07 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 52.68 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 183 SIREELGlDSNDIIISYVAEMSKRKNQLYLLKNWKKITyKCPRAKLVLIGSGEmgevYKEYVANHNLEgVIFAGYRQ--D 260
Cdd:cd03814 188 ALRRRLG-PPGRPLLLYVGRLAPEKNLEALLDADLPLA-ASPPVRLVVVGDGP----ARAELEARGPD-VIFTGFLTgeE 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 261 IKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNM 340
Cdd:cd03814 261 LARAYASADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIVRPGGTGALVEPGDAAAFAAALRALLEDPELRRRM 340
|
170 180
....*....|....*....|....*
gi 1032578817 341 GLNNEQIKERYSETTVLEQMKCIYD 365
Cdd:cd03814 341 AARARAEAERYSWEAFLDNLLDYYA 365
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
143-367 |
4.24e-07 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 51.18 E-value: 4.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 143 MNEEDYKSAqqFFNKENVHFINgigvnlseyNAVNID-----NHTSIREELGLDSNDIIISYVAE--MSKRKNQLYLLKN 215
Cdd:cd03825 148 LADMVRRSP--LLKGLPVVVIP---------NGIDTEifapvDKAKARKRLGIPQDKKVILFGAEsvTKPRKGFDELIEA 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 216 WKKITYKCpRAKLVLIGSGEMgevyKEYVANHNlegVIFAGYRQDIKE--IIYQS-DIVALLSTQEGLPRCVLEGMALHK 292
Cdd:cd03825 217 LKLLATKD-DLLLVVFGKNDP----QIVILPFD---IISLGYIDDDEQlvDIYSAaDLFVHPSLADNLPNTLLEAMACGT 288
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1032578817 293 PLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLN-NEQIKERYSETTVLEQMKCIYDKV 367
Cdd:cd03825 289 PVVAFDTGGSPEIVQHGVTGYLVPPGDVQALAEAIEWLLANPKERESLGERaRALAENHFDQRVQAQRYLELYKDL 364
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
22-166 |
3.08e-06 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 46.76 E-value: 3.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 22 QYFLNNGHEVYAVA-KDDGNKNVIENLGVKCIDIDIERSPFKLSNIKAYFQLKSILRINNFDLITTHTPF--ISFLIRLV 98
Cdd:pfam13439 12 RALARRGHEVTVVTpGGPGPLAEEVVRVVRVPRVPLPLPPRLLRSLAFLRRLRRLLRRERPDVVHAHSPFplGLAALAAR 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1032578817 99 NLNHTKLIYTAHG----FHFYKGGSVVKNTLYKNMERFAAKFTDEIAVMNEEDYKSAQQFF--NKENVHFI-NGI 166
Cdd:pfam13439 92 LRLGIPLVVTYHGlfpdYKRLGARLSPLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYgvPPEKIRVIpNGV 166
|
|
| PRK15490 |
PRK15490 |
Vi polysaccharide biosynthesis glycosyltransferase TviE; |
224-334 |
3.87e-06 |
|
Vi polysaccharide biosynthesis glycosyltransferase TviE;
Pssm-ID: 185387 [Multi-domain] Cd Length: 578 Bit Score: 48.54 E-value: 3.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 224 PRAKLVLIGSGEM-GEVYKEYVANHNLEGVIFAGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGN 302
Cdd:PRK15490 428 PATRFVLVGDGDLrAEAQKRAEQLGILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAGGS 507
|
90 100 110
....*....|....*....|....*....|....*...
gi 1032578817 303 TDLVQNGINGF------TIELDNDEELIDKFITLIQNK 334
Cdd:PRK15490 508 AECFIEGVSGFilddaqTVNLDQACRYAEKLVNLWRSR 545
|
|
| GT4-like |
cd05844 |
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ... |
197-342 |
7.22e-06 |
|
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340860 [Multi-domain] Cd Length: 365 Bit Score: 47.45 E-value: 7.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 197 ISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANhnLEGVIFAGY--RQDIKEIIYQSDIVALL 274
Cdd:cd05844 192 ILFVGRLVEKKGCDVLIEAFRRLAARHPTARLVIAGDGPLRPALQALAAA--LGRVRFLGAlpHAEVQDWMRRAEIFCLP 269
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1032578817 275 ST------QEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGL 342
Cdd:cd05844 270 SVtaasgdSEGLGIVLLEAAACGVPVVSSRHGGIPEAILDGETGFLVPEGDVDALADALQALLADRALADRMGG 343
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
196-352 |
8.81e-06 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 47.40 E-value: 8.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 196 IISYVAEMSKRKNqlylLKNWKKITYKCPRAKLVLIGSGEMGEVYKEYVANHNlegVIFAGYRQ--DIKEIIYQSDIVAL 273
Cdd:PLN02871 265 LIVYVGRLGAEKN----LDFLKRVMERLPGARLAFVGDGPYREELEKMFAGTP---TVFTGMLQgdELSQAYASGDVFVM 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 274 LSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLV---QNGINGFTIELDNDEELIDKFITLIQNKNLRHNMGLNNEQIKER 350
Cdd:PLN02871 338 PSESETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLYTPGDVDDCVEKLETLLADPELRERMGAAAREEVEK 417
|
..
gi 1032578817 351 YS 352
Cdd:PLN02871 418 WD 419
|
|
| PRK09922 |
PRK09922 |
lipopolysaccharide 1,6-galactosyltransferase; |
227-370 |
2.36e-05 |
|
lipopolysaccharide 1,6-galactosyltransferase;
Pssm-ID: 182148 [Multi-domain] Cd Length: 359 Bit Score: 45.86 E-value: 2.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 227 KLVLIGSGEMGEVYKEYVANHNLEG-VIFAGYRQDIKEI----IYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIR- 300
Cdd:PRK09922 212 QLHIIGDGSDFEKCKAYSRELGIEQrIIWHGWQSQPWEVvqqkIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSDCMs 291
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1032578817 301 GNTDLVQNGINGFTIELDNDEELIDKFITLIQNKnlrhnMGLNNEQIK---ERYSETTVLEQMKCIYDKVLSK 370
Cdd:PRK09922 292 GPRDIIKPGLNGELYTPGNIDEFVGKLNKVISGE-----VKYQHDAIPnsiERFYEVLYFKNLNNALFSKLQK 359
|
|
| PRK15484 |
PRK15484 |
lipopolysaccharide N-acetylglucosaminyltransferase; |
180-313 |
5.77e-05 |
|
lipopolysaccharide N-acetylglucosaminyltransferase;
Pssm-ID: 185381 [Multi-domain] Cd Length: 380 Bit Score: 44.78 E-value: 5.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 180 NHTSI-REELGLDSNDIIISYVAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIG------SGEMGEVYKEY--VANHNLE 250
Cdd:PRK15484 178 NPQPNlRQQLNISPDETVLLYAGRISPDKGILLLMQAFEKLATAHSNLKLVVVGdptassKGEKAAYQKKVleAAKRIGD 257
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1032578817 251 GVIFAGYR--QDIKEIIYQSDIVALLST-QEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGF 313
Cdd:PRK15484 258 RCIMLGGQppEKMHNYYPLADLVVVPSQvEEAFCMVAVEAMAAGKPVLASTKGGITEFVLEGITGY 323
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
224-321 |
2.52e-04 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 43.10 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 224 PRAKLVLIGSGEMGEVYKEYVANHNL-EGVIFAGYRQDIKEIIYQSDIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGN 302
Cdd:PRK15179 547 PKVRFIMVGGGPLLESVREFAQRLGMgERILFTGLSRRVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAGGA 626
|
90
....*....|....*....
gi 1032578817 303 TDLVQNGINGFTIELDNDE 321
Cdd:PRK15179 627 GEAVQEGVTGLTLPADTVT 645
|
|
| GT4_mannosyltransferase-like |
cd03822 |
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ... |
32-355 |
4.48e-04 |
|
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.
Pssm-ID: 340849 [Multi-domain] Cd Length: 370 Bit Score: 41.99 E-value: 4.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 32 YAVAKDDGNKNVIEnlgVKCIdidierspfklsNIKAYFQLKSILRINNFDLITTHTPFISFlirlvnlNHTKLIYTAHG 111
Cdd:cd03822 42 DEILKDDDFEVPNE---IKSW------------NSNEYFRLLDHLNFKKPDVVHIQHEFGIF-------GGKYGLYALGL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 112 FHFYKGGSVVknTL-------------YKNMERFAAKfTDEIAVMNE------EDYKSaqqfFNKENVHFINgIGVNLse 172
Cdd:cd03822 100 LLHLRIPVIT--TLhtvldlsdpgkqaLKVLFRIATL-SERVVVMAPisrfllVRIKL----IPAVNIEVIP-HGVPE-- 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 173 ynaVNIDNHTSIREELGLDSNDIIISYvAEMSKRKNQLYLLKNWKKITYKCPRAKLVLIGS------GEMGEVYKE-YVA 245
Cdd:cd03822 170 ---VPQDPTTALKRLLLPEGKKVILTF-GFIGPGKGLEILLEALPELKAEFPDVRLVIAGElhpslaRYEGERYRKaAIE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 246 NHNLEGVIFAGYR----QDIKEIIYQSDIVAL--LSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGiNGFTIELDN 319
Cdd:cd03822 246 ELGLQDHVDFHNNflpeEEVPRYISAADVVVLpyLNTEQSSSGTLSYAIACGKPVISTPLRHAEELLADG-RGVLVPFDD 324
|
330 340 350
....*....|....*....|....*....|....*.
gi 1032578817 320 DEELIDKFITLIQNKNLRHNMglnnEQIKERYSETT 355
Cdd:cd03822 325 PSAIAEAILRLLEDDERRQAI----AERAYAYARAM 356
|
|
| Glyco_trans_4_4 |
pfam13579 |
Glycosyl transferase 4-like domain; |
28-142 |
1.42e-03 |
|
Glycosyl transferase 4-like domain;
Pssm-ID: 433325 [Multi-domain] Cd Length: 158 Bit Score: 38.92 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 28 GHEVYAVAKDDGNKNVIEN-LGVKCIDIDIERSPFKLSNIKAYFQLKSILRINNFDLITTHTPFISFLIRLVNLNH-TKL 105
Cdd:pfam13579 18 GHEVRVVTPGGPPGRPELVgDGVRVHRLPVPPRPSPLADLAALRRLRRLLRAERPDVVHAHSPTAGLAARLARRRRgVPL 97
|
90 100 110
....*....|....*....|....*....|....*..
gi 1032578817 106 IYTAHGFHFYKGGSVVKNtLYKNMERFAAKFTDEIAV 142
Cdd:pfam13579 98 VVTVHGLALDYGSGWKRR-LARALERRLLRRADAVVV 133
|
|
| GT4_AmsK-like |
cd04946 |
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ... |
252-352 |
7.27e-03 |
|
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.
Pssm-ID: 340854 [Multi-domain] Cd Length: 401 Bit Score: 38.21 E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032578817 252 VIFAGY--RQDIKEIIYQS--DIVALLSTQEGLPRCVLEGMALHKPLIVSHIRGNTDLVQNGINGFTieLDND---EELI 324
Cdd:cd04946 285 VNFTGEvsNKEVKQLYKENdvDVFVNVSESEGIPVSIMEAISFGIPVIATNVGGTREIVENETNGLL--LDKDptpNEIV 362
|
90 100
....*....|....*....|....*....
gi 1032578817 325 DKFITLIQNKNLRHNMGLNN-EQIKERYS 352
Cdd:cd04946 363 SSIMKFYLDGGDYKTMKISArECWEERFN 391
|
|
| |
