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Conserved domains on  [gi|1033076920|ref|WP_064387208|]
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MULTISPECIES: NAD(P)/FAD-dependent oxidoreductase [Pseudoalteromonas]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11457516)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
57-533 0e+00

FAD-dependent dehydrogenase [General function prediction only];


:

Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 740.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920  57 LDIEVDNEEALLNAFTKDQHVKPapdtsykfvahapanLTERPVVIGFGPCGLFAGLVLAQMGFNPIILERGKEVRERTK 136
Cdd:COG2509     6 LKLPLDDEEALKAAIAKKLGIPS---------------LKYDVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTC 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 137 DTFGFWRKRTLNTESNVQFGEGGAGTFSDGKLYSQVKDPKHYGRKVITEFVEAGAPDEILYVSKPHIGTFKLVTMIEKMR 216
Cdd:COG2509    71 PVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNTRSKDPQGLIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIR 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 217 ARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNGEKLNTRHVVLAVGHSARDTFKMIHDKGIYVEAKPFSVGFRIEHKQS 296
Cdd:COG2509   151 EYIEELGGEIRFNTRVTDILIEDGRVKGVVTNDGEEIEADAVILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQE 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 297 MIDECRFGPNAGNPILGSADYKLVHHCDN-GRTVYSFCMCPGGTVVAATSEEGRVVTNGMSQYSRSERNANSAIVVGITP 375
Cdd:COG2509   231 LIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRGVYTFCMCPGGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTP 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 376 EkDFPGHPLAGIDLQRKLEEQAYALGGSNYDAPAQLIGDFLKGKASGDLGDVQPSFTPGIKLTDLANVLPQFAIDAIREA 455
Cdd:COG2509   311 T-DFPGGPLAGIEYQRSIERLANELGGGNYKAPAQRLGDFLAGRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREA 389

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1033076920 456 IPAFNKQIRGFSTNDGLLTGVETRTSSPISIKRDKSFQSiNTKGLYPagegagyaggILSAGIDGIKAAEAVALSMLE 533
Cdd:COG2509   390 LEAFDKKIPGFASDDALLYGVETRTSSPVRIPRDEDLET-NIKGLYPagegagyaggIVSAAVDGIRVAEAIAEKLGP 466
 
Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
57-533 0e+00

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 740.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920  57 LDIEVDNEEALLNAFTKDQHVKPapdtsykfvahapanLTERPVVIGFGPCGLFAGLVLAQMGFNPIILERGKEVRERTK 136
Cdd:COG2509     6 LKLPLDDEEALKAAIAKKLGIPS---------------LKYDVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTC 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 137 DTFGFWRKRTLNTESNVQFGEGGAGTFSDGKLYSQVKDPKHYGRKVITEFVEAGAPDEILYVSKPHIGTFKLVTMIEKMR 216
Cdd:COG2509    71 PVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNTRSKDPQGLIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIR 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 217 ARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNGEKLNTRHVVLAVGHSARDTFKMIHDKGIYVEAKPFSVGFRIEHKQS 296
Cdd:COG2509   151 EYIEELGGEIRFNTRVTDILIEDGRVKGVVTNDGEEIEADAVILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQE 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 297 MIDECRFGPNAGNPILGSADYKLVHHCDN-GRTVYSFCMCPGGTVVAATSEEGRVVTNGMSQYSRSERNANSAIVVGITP 375
Cdd:COG2509   231 LIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRGVYTFCMCPGGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTP 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 376 EkDFPGHPLAGIDLQRKLEEQAYALGGSNYDAPAQLIGDFLKGKASGDLGDVQPSFTPGIKLTDLANVLPQFAIDAIREA 455
Cdd:COG2509   311 T-DFPGGPLAGIEYQRSIERLANELGGGNYKAPAQRLGDFLAGRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREA 389

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1033076920 456 IPAFNKQIRGFSTNDGLLTGVETRTSSPISIKRDKSFQSiNTKGLYPagegagyaggILSAGIDGIKAAEAVALSMLE 533
Cdd:COG2509   390 LEAFDKKIPGFASDDALLYGVETRTSSPVRIPRDEDLET-NIKGLYPagegagyaggIVSAAVDGIRVAEAIAEKLGP 466
PRK07233 PRK07233
hypothetical protein; Provisional
 100-262 1.88e-09

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 59.90  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILERGKEVR-------------ER------TKDTFGFWRKRTLNTESNVQFGEGGA 160
Cdd:PRK07233    3 AIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGglaasfefgglpiERfyhhifKSDEALLELLDELGLEDKLRWRETKT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 161 GTFSDGKLYS-----------------------------QVKDPK-------------HYGRKVITEFVE---------- 188
Cdd:PRK07233   83 GYYVDGKLYPlgtplellrfphlslidkfrlglltllarRIKDWRaldkvpaeewlrrWSGEGVYEVFWEplleskfgdy 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 189 --------------------AGAPDEIL-YVSkphiGTFKlvTMIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTGLTL 247
Cdd:PRK07233  163 addvsaawlwsrikrrgnrrYSLFGEKLgYLE----GGFA--TLIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEV 236

                         250
                  ....*....|....*
gi 1033076920 248 sNGEKLNTRHVVLAV 262
Cdd:PRK07233  237 -DGEEEDFDAVISTA 250
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 210-270 4.43e-04

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 42.86  E-value: 4.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1033076920 210 TMIEKMRARIieLGGEIRFSTRVDDIHIDDGQVTgLTLSNGEKLNTRHVVLAV--GHSARDTF 270
Cdd:pfam01593 207 ALPDALAAQL--LGGDVRLNTRVRSIDREGDGVT-VTLTDGEVIEADAVIVTVplGVLKRILF 266
 
Name Accession Description Interval E-value
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
57-533 0e+00

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 740.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920  57 LDIEVDNEEALLNAFTKDQHVKPapdtsykfvahapanLTERPVVIGFGPCGLFAGLVLAQMGFNPIILERGKEVRERTK 136
Cdd:COG2509     6 LKLPLDDEEALKAAIAKKLGIPS---------------LKYDVVIVGAGPAGLFAALELAEAGLKPLVLERGKDVEERTC 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 137 DTFGFWRKRTLNTESNVQFGEGGAGTFSDGKLYSQVKDPKHYGRKVITEFVEAGAPDEILYVSKPHIGTFKLVTMIEKMR 216
Cdd:COG2509    71 PVAEFWRKGKCNPESNIQFGEGGAGTFSDGKLNTRSKDPQGLIRYVLEIFVKFGAPEEILYAAKPHIGTDKLPKVVKNIR 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 217 ARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNGEKLNTRHVVLAVGHSARDTFKMIHDKGIYVEAKPFSVGFRIEHKQS 296
Cdd:COG2509   151 EYIEELGGEIRFNTRVTDILIEDGRVKGVVTNDGEEIEADAVILAPGHSARDWFEMLHRLGVKLEAKPFDIGVRVEHPQE 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 297 MIDECRFGPNAGNPILGSADYKLVHHCDN-GRTVYSFCMCPGGTVVAATSEEGRVVTNGMSQYSRSERNANSAIVVGITP 375
Cdd:COG2509   231 LIDRIQYGKFAGHPLLGAAEYKLVYQTKNyGRGVYTFCMCPGGFVVAEASEPGLVVVNGMSYSDRKSENANFALLVSVTP 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 376 EkDFPGHPLAGIDLQRKLEEQAYALGGSNYDAPAQLIGDFLKGKASGDLGDVQPSFTPGIKLTDLANVLPQFAIDAIREA 455
Cdd:COG2509   311 T-DFPGGPLAGIEYQRSIERLANELGGGNYKAPAQRLGDFLAGRRSTELGSVEPTYKPGVTPGDLSLVLPYRILDALREA 389

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1033076920 456 IPAFNKQIRGFSTNDGLLTGVETRTSSPISIKRDKSFQSiNTKGLYPagegagyaggILSAGIDGIKAAEAVALSMLE 533
Cdd:COG2509   390 LEAFDKKIPGFASDDALLYGVETRTSSPVRIPRDEDLET-NIKGLYPagegagyaggIVSAAVDGIRVAEAIAEKLGP 466
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 210-273 1.36e-10

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 63.72  E-value: 1.36e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1033076920 210 TMIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNGEKLNTRHVVLAVghSARDTFKMI 273
Cdd:COG1233   223 ALADALARLAEELGGEIRTGAEVERILVEGGRATGVRLADGEEIRADAVVSNA--DPAHTYLRL 284
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 216-266 2.88e-10

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 62.56  E-value: 2.88e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1033076920 216 RARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNGEKLNTRHVVLAVGHSA 266
Cdd:COG3349   219 LAYLEARGGEVRLGTRVRALEFDGGRVTGLVLADGETVPADAVVLAVPPEV 269
PRK07233 PRK07233
hypothetical protein; Provisional
 100-262 1.88e-09

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 59.90  E-value: 1.88e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILERGKEVR-------------ER------TKDTFGFWRKRTLNTESNVQFGEGGA 160
Cdd:PRK07233    3 AIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGglaasfefgglpiERfyhhifKSDEALLELLDELGLEDKLRWRETKT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 161 GTFSDGKLYS-----------------------------QVKDPK-------------HYGRKVITEFVE---------- 188
Cdd:PRK07233   83 GYYVDGKLYPlgtplellrfphlslidkfrlglltllarRIKDWRaldkvpaeewlrrWSGEGVYEVFWEplleskfgdy 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 189 --------------------AGAPDEIL-YVSkphiGTFKlvTMIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTGLTL 247
Cdd:PRK07233  163 addvsaawlwsrikrrgnrrYSLFGEKLgYLE----GGFA--TLIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEV 236

                         250
                  ....*....|....*
gi 1033076920 248 sNGEKLNTRHVVLAV 262
Cdd:PRK07233  237 -DGEEEDFDAVISTA 250
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 100-266 2.51e-08

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 55.71  E-value: 2.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILERGKEVRERTK------------DTFGFWRkrtlntesnvQFGEGGA----GTF 163
Cdd:COG0654     7 LIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRgialsprslellRRLGLWD----------RLLARGApirgIRV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 164 SDGklysqvkdpkHYGRKVITEFVEAGAPDEILYVSKPHIGTFklvtmiekMRARIIELGGEIRFSTRVDDIHIDDGQVT 243
Cdd:COG0654    77 RDG----------SDGRVLARFDAAETGLPAGLVVPRADLERA--------LLEAARALGVELRFGTEVTGLEQDADGVT 138

                         170       180
                  ....*....|....*....|....
gi 1033076920 244 gLTLSNGEKLNTRHVVLAVG-HSA 266
Cdd:COG0654   139 -VTLADGRTLRADLVVGADGaRSA 161
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
105-267 3.67e-08

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 54.97  E-value: 3.67e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 105 GPCGLFAGLVLAQMGFNPIILERGKEVRErtKDTFGFWRKRTLNTESNVQFGEGGAGTFSDGKLYSQVKDPKHYGRKVIT 184
Cdd:COG0644     2 GPAGSAAARRLARAGLSVLLLEKGSFPGD--KICGGGLLPRALEELEPLGLDEPLERPVRGARFYSPGGKSVELPPGRGG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 185 EFVeagapdeilyVSKPHigtfklvtMIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTgLTLSNGEKLNTRHVVLAVGH 264
Cdd:COG0644    80 GYV----------VDRAR--------FDRWLAEQAEEAGAEVRTGTRVTDVLRDDGRVV-VRTGDGEEIRADYVVDADGA 140


                  ...
gi 1033076920 265 SAR 267
Cdd:COG0644   141 RSL 143
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
100-276 2.75e-07

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 52.60  E-value: 2.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILERG-----------------------KEVRERTKDTFGFWRkrTLNTESNVQFG 156
Cdd:COG0665     6 VVIGGGIAGLSTAYHLARRGLDVTVLERGrpgsgasgrnagqlrpglaaladRALVRLAREALDLWR--ELAAELGIDCD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 157 EGGAGTFsdgKLYSQVKDPKHYgRKVITEFVEAGAPDEIL----------YVSKPHI---------GTFKLVTMIEKMRA 217
Cdd:COG0665    84 FRRTGVL---YLARTEAELAAL-RAEAEALRALGLPVELLdaaelrerepGLGSPDYagglydpddGHVDPAKLVRALAR 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1033076920 218 RIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNGEkLNTRHVVLAVGHSARDTFKMIHDK 276
Cdd:COG0665   160 AARAAGVRIREGTPVTGLEREGGRVTGVRTERGT-VRADAVVLAAGAWSARLLPMLGLR 217
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 100-274 7.03e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 51.79  E-value: 7.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILERGKEVrertkdtFGFWRKRTLNtesnvqfgegGAGTFSDGKLYS-----QVKD 174
Cdd:COG2072    10 VVIGAGQAGLAAAYHLRRAGIDFVVLEKADDV-------GGTWRDNRYP----------GLRLDTPSHLYSlpffpNWSD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 175 PKHYGRKvitefveagapDEIL-YvskphigtfkLVTMIEKmrariIELGGEIRFSTRVDDIHIDDGqvTG---LTLSNG 250
Cdd:COG2072    73 DPDFPTG-----------DEILaY----------LEAYADK-----FGLRRPIRFGTEVTSARWDEA--DGrwtVTTDDG 124

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1033076920 251 EKLNTRHVVLAVGH---------SARDTFK--MIH 274
Cdd:COG2072   125 ETLTARFVVVATGPlsrpkipdiPGLEDFAgeQLH 159
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 200-266 7.54e-07

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 51.76  E-value: 7.54e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1033076920 200 KPHIGTFK--LVTMIEKMRARIIElgGEIRFSTRVDDIHIDDGQVTgLTLSNGEKLNTRHVVLAVGHSA 266
Cdd:COG1232   199 GEVFGYLRggLGTLVEALAEALEA--GEIRLGTRVTAIEREGGGWR-VTTSDGETIEADAVVSATPAPA 264
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
100-267 1.29e-05

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 47.04  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILERGkevrertkdtfgfwrkrtlntesnvQFGeggagtfsdGKLysqvkdpkhyg 179
Cdd:COG0492     4 VIIGAGPAGLTAAIYAARAGLKTLVIEGG-------------------------EPG---------GQL----------- 38

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 180 rkVITEFVE--AGAPDEILyvskphiGTfklvTMIEKMRARIIELGGEIRFsTRVDDIHIDDGQVTgLTLSNGEKLNTRH 257
Cdd:COG0492    39 --ATTKEIEnyPGFPEGIS-------GP----ELAERLREQAERFGAEILL-EEVTSVDKDDGPFR-VTTDDGTEYEAKA 103

                         170
                  ....*....|
gi 1033076920 258 VVLAVGHSAR 267
Cdd:COG0492   104 VIIATGAGPR 113
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 211-263 1.40e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 44.44  E-value: 1.40e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1033076920 211 MIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNG----EKLNTRHVVLAVG 263
Cdd:COG1053   136 LLATLYQAALRLGVEIFTETEVLDLIVDDGRVVGVVARDRtgeiVRIRAKAVVLATG 192
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
213-308 4.33e-04

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 42.83  E-value: 4.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1033076920 213 EKMRARIIELGGEIRFSTRVDDIHIDDGQVTgLTLSNGEkLNTRHVVLAVG-HSAR--------DTFKMIHDKGIY---- 279
Cdd:COG0579   157 RALAENAEANGVELLLNTEVTGIEREGDGWE-VTTNGGT-IRARFVINAAGlYADRlaqmagigKDFGIFPVKGEYlvld 234

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1033076920 280 -----VEAK---------PF-SVGFRIehkqsMID-ECRFGPNAG 308
Cdd:COG0579   235 kpaelVNAKvypvpdpgaPFlGVHLTR-----TIDgNLLFGPNAV 274
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 210-270 4.43e-04

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 42.86  E-value: 4.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1033076920 210 TMIEKMRARIieLGGEIRFSTRVDDIHIDDGQVTgLTLSNGEKLNTRHVVLAV--GHSARDTF 270
Cdd:pfam01593 207 ALPDALAAQL--LGGDVRLNTRVRSIDREGDGVT-VTLTDGEVIEADAVIVTVplGVLKRILF 266
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
211-263 4.81e-04

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 42.66  E-value: 4.81e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1033076920 211 MIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTgLTLSNGEKLNTRHVVLAVG 263
Cdd:PRK07333  113 LINALRKRAEALGIDLREATSVTDFETRDEGVT-VTLSDGSVLEARLLVAADG 164
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
211-263 5.56e-04

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 42.55  E-value: 5.56e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1033076920 211 MIEKMRARIIELGGEIRFSTRVDDIHIDDGQVTGLTLSNG----EKLNTRHVVLAVG 263
Cdd:PRK08274  133 LVNALYRSAERLGVEIRYDAPVTALELDDGRFVGARAGSAaggaERIRAKAVVLAAG 189
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
227-270 9.83e-04

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 41.86  E-value: 9.83e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1033076920 227 RFSTRVDDIHIDDGQVTgLTLSNGEKLNTRHVVLAVGHSARDTF 270
Cdd:COG4529   124 HIRAEVVDLERDDGGYR-VTLADGETLRADAVVLATGHPPPAPP 166
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
196-267 2.10e-03

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 40.58  E-value: 2.10e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1033076920 196 LYVSKPHIGTFKLVTmiEKMRARIIELGGEIRFSTRVDDIHIDDGQVTgLTLSNGEkLNTRHVVLAVG-HSAR 267
Cdd:PRK11728  138 IFVPSTGIVDYRAVA--EAMAELIQARGGEIRLGAEVTALDEHANGVV-VRTTQGE-YEARTLINCAGlMSDR 206
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
100-127 4.94e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 39.50  E-value: 4.94e-03
                          10        20
                  ....*....|....*....|....*...
gi 1033076920 100 VVIGFGPCGLFAGLVLAQMGFNPIILER 127
Cdd:PRK06183   14 VIVGAGPVGLTLANLLGQYGVRVLVLER 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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