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Conserved domains on  [gi|1039509106|ref|WP_064844817|]
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MULTISPECIES: LuxR family transcriptional regulator [unclassified Rhizobium]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 10507064)

helix-turn-helix (HTH) transcriptional regulator containing an N-terminal an autoinducer binding domain and a LuxR family HTH DNA-binding domain; may act as an activator or repressor in response to an inducer

Gene Ontology:  GO:0006355|GO:0003677|GO:0003700
PubMed:  15808743|19076237|10473770|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Autoind_bind pfam03472
Autoinducer binding domain; This domain is found a a large family of transcriptional ...
 19-165 4.02e-31

Autoinducer binding domain; This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


:

Pssm-ID: 427319  Cd Length: 148  Bit Score: 112.07  E-value: 4.02e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  19 TLQDLETTLDEVRHIYAISHMVLHVT-RSATAADNPLLMLTYPPEWVKQYIARDYFSIDPVVRLGRRGFLPVEWSASKWD 97
Cdd:pfam03472   1 SEEELFDALARLAAALGFDHFAYGARaPLGLSAPDVLVLSNYPAEWLDRYDEANYFAIDPVVRHARRSSSPFSWSDVLFA 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  98 SGRACG--FFKEAMAFGIgRQGVTLPVRGPQGERALFTVTSTHADSYWRQFRMDsMRDLQFLAHHLHDRA 165
Cdd:pfam03472  81 EARGAErrFLDEARDFGL-RDGYTVPVHGPGGRLGALSFAGPGEDLDPAEAIEA-AARLQLLAIYAHLRL 148
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 180-234 1.03e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


:

Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 66.40  E-value: 1.03e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
 
Name Accession Description Interval E-value
Autoind_bind pfam03472
Autoinducer binding domain; This domain is found a a large family of transcriptional ...
 19-165 4.02e-31

Autoinducer binding domain; This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 427319  Cd Length: 148  Bit Score: 112.07  E-value: 4.02e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  19 TLQDLETTLDEVRHIYAISHMVLHVT-RSATAADNPLLMLTYPPEWVKQYIARDYFSIDPVVRLGRRGFLPVEWSASKWD 97
Cdd:pfam03472   1 SEEELFDALARLAAALGFDHFAYGARaPLGLSAPDVLVLSNYPAEWLDRYDEANYFAIDPVVRHARRSSSPFSWSDVLFA 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  98 SGRACG--FFKEAMAFGIgRQGVTLPVRGPQGERALFTVTSTHADSYWRQFRMDsMRDLQFLAHHLHDRA 165
Cdd:pfam03472  81 EARGAErrFLDEARDFGL-RDGYTVPVHGPGGRLGALSFAGPGEDLDPAEAIEA-AARLQLLAIYAHLRL 148
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
54-240 3.22e-15

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 71.33  E-value: 3.22e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  54 LLMLTYPPEWVKQYIARDYFSIDPVVRLGRRGFLPVEWSASKWDSGRACGFFKEAMAFGIGRQGVTLPVRGPQGERALFT 133
Cdd:COG2771     2 LLLALALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 134 VTSTHADSYWRQFRMDSMRDLQFLAHHLHDRAMVLSGMRKTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQL 213
Cdd:COG2771    82 LALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVRT 161

                         170       180
                  ....*....|....*....|....*..
gi 1039509106 214 YLASARRKLTVATTSEAVAKATALELI 240
Cdd:COG2771   162 HLKRIYRKLGVSSRAELVALALRLGLI 188
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 180-234 1.03e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 66.40  E-value: 1.03e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 177-234 2.55e-12

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 59.85  E-value: 2.55e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039509106  177 FPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 180-240 7.15e-12

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 60.68  E-value: 7.15e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKATALELI 240
Cdd:COG2197    70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRLGLL 130
PRK10188 PRK10188
transcriptional regulator SdiA;
58-240 4.94e-10

transcriptional regulator SdiA;


Pssm-ID: 182292 [Multi-domain]  Cd Length: 240  Bit Score: 57.87  E-value: 4.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  58 TYPPEWVKQYIARDYFSIDPVVRLG--RRGFLPveWS-------ASKWDSGRACGFfkeamafgigRQGVTLPVRGPQge 128
Cdd:PRK10188   62 TYPEAWVSHYQAENYFAIDPVLKPEnfSQGHLM--WNddlfseaQALWDAARAHGL----------RRGVTQCLMLPN-- 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 129 RAL----FTVTSTHADSYWR---QFRMDSMRDLQFLA-HHLHDRAMVLSGMRktadfpqLSRRELQCLQMTANGLLAKQI 200
Cdd:PRK10188  128 RALgflsFSRCSAREIPILSdelELRLQLLVRESLMAlMRLEDEMVMTPEMN-------FSKREKEILKWTAEGKTSAEI 200

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1039509106 201 CARLCISVSAVQLYLASARRKLTVATTSEAVAKATALELI 240
Cdd:PRK10188  201 AMILSISENTVNFHQKNMQKKFNAPNKTQIACYAAATGLI 240
GerE pfam00196
Bacterial regulatory proteins, luxR family;
180-234 9.19e-09

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 50.28  E-value: 9.19e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
173-224 1.86e-03

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 38.29  E-value: 1.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1039509106 173 KTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTV 224
Cdd:PRK10403  147 EEDPFSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNV 198
 
Name Accession Description Interval E-value
Autoind_bind pfam03472
Autoinducer binding domain; This domain is found a a large family of transcriptional ...
 19-165 4.02e-31

Autoinducer binding domain; This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 427319  Cd Length: 148  Bit Score: 112.07  E-value: 4.02e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  19 TLQDLETTLDEVRHIYAISHMVLHVT-RSATAADNPLLMLTYPPEWVKQYIARDYFSIDPVVRLGRRGFLPVEWSASKWD 97
Cdd:pfam03472   1 SEEELFDALARLAAALGFDHFAYGARaPLGLSAPDVLVLSNYPAEWLDRYDEANYFAIDPVVRHARRSSSPFSWSDVLFA 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  98 SGRACG--FFKEAMAFGIgRQGVTLPVRGPQGERALFTVTSTHADSYWRQFRMDsMRDLQFLAHHLHDRA 165
Cdd:pfam03472  81 EARGAErrFLDEARDFGL-RDGYTVPVHGPGGRLGALSFAGPGEDLDPAEAIEA-AARLQLLAIYAHLRL 148
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
54-240 3.22e-15

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 71.33  E-value: 3.22e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  54 LLMLTYPPEWVKQYIARDYFSIDPVVRLGRRGFLPVEWSASKWDSGRACGFFKEAMAFGIGRQGVTLPVRGPQGERALFT 133
Cdd:COG2771     2 LLLALALLLLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 134 VTSTHADSYWRQFRMDSMRDLQFLAHHLHDRAMVLSGMRKTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQL 213
Cdd:COG2771    82 LALLLLLALLALLAALLARLAALLLALALAALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVRT 161

                         170       180
                  ....*....|....*....|....*..
gi 1039509106 214 YLASARRKLTVATTSEAVAKATALELI 240
Cdd:COG2771   162 HLKRIYRKLGVSSRAELVALALRLGLI 188
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 180-234 1.03e-14

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 66.40  E-value: 1.03e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:cd06170     1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQLVAYA 55
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 177-234 2.55e-12

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 59.85  E-value: 2.55e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039509106  177 FPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQAVRLA 58
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 180-240 7.15e-12

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 60.68  E-value: 7.15e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKATALELI 240
Cdd:COG2197    70 LTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELVLLALRLGLL 130
PRK10188 PRK10188
transcriptional regulator SdiA;
58-240 4.94e-10

transcriptional regulator SdiA;


Pssm-ID: 182292 [Multi-domain]  Cd Length: 240  Bit Score: 57.87  E-value: 4.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  58 TYPPEWVKQYIARDYFSIDPVVRLG--RRGFLPveWS-------ASKWDSGRACGFfkeamafgigRQGVTLPVRGPQge 128
Cdd:PRK10188   62 TYPEAWVSHYQAENYFAIDPVLKPEnfSQGHLM--WNddlfseaQALWDAARAHGL----------RRGVTQCLMLPN-- 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 129 RAL----FTVTSTHADSYWR---QFRMDSMRDLQFLA-HHLHDRAMVLSGMRktadfpqLSRRELQCLQMTANGLLAKQI 200
Cdd:PRK10188  128 RALgflsFSRCSAREIPILSdelELRLQLLVRESLMAlMRLEDEMVMTPEMN-------FSKREKEILKWTAEGKTSAEI 200

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1039509106 201 CARLCISVSAVQLYLASARRKLTVATTSEAVAKATALELI 240
Cdd:PRK10188  201 AMILSISENTVNFHQKNMQKKFNAPNKTQIACYAAATGLI 240
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 171-240 4.67e-09

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 51.50  E-value: 4.67e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 171 MRKTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKATALELI 240
Cdd:COG5905     4 SSSTSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAVVWALRLGLL 73
GerE pfam00196
Bacterial regulatory proteins, luxR family;
180-234 9.19e-09

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 50.28  E-value: 9.19e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039509106 180 LSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKA 234
Cdd:pfam00196   3 LSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELVRMA 57
PRK13870 PRK13870
transcriptional regulator TraR; Provisional
 11-240 1.13e-07

transcriptional regulator TraR; Provisional


Pssm-ID: 172390 [Multi-domain]  Cd Length: 234  Bit Score: 51.15  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  11 LDRISASPTLQDLETTL-----DEVRHIYAISHMVLHVT-RSATAADNpllmltYPPEWVKQYIARDYFSIDPVVRLGRR 84
Cdd:PRK13870    5 LDKLTDLAAIEGDECILktglaDIADHFGFTGYAYLHIQhRHITAVTN------YHREWQSVYFDKKFDALDPVVKRARS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106  85 GFLPVEWSASKWD---SGRACGFFKEAMAFGIgRQGVTLPVRGPQGERALFTVTSTHAdsywrqfRMDSMRDLQFLAH-- 159
Cdd:PRK13870   79 RKHIFTWSGEQERprlSKDERAFYAHAADFGI-RSGITIPIKTANGSMSMFTLASEKP-------VIDLDREIDAVAAaa 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 160 ---HLHDRAMVLSGMRKTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKATA 236
Cdd:PRK13870  151 tigQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIR 230


                  ....
gi 1039509106 237 LELI 240
Cdd:PRK13870  231 RKLI 234
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 157-238 8.22e-07

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 47.79  E-value: 8.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 157 LAHHLHDRAMVLSGMRKTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTVATTSEAVAKATA 236
Cdd:COG4566   115 LARDRARRAERARRAELRARLASLTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARSLAELVRLALA 194


                  ..
gi 1039509106 237 LE 238
Cdd:COG4566   195 LG 196
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
147-240 9.44e-07

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 47.78  E-value: 9.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039509106 147 RMDSMRDLQFLAHHLHDRAMVLSGMRKTADFPQLSRRELqclqmTANGLLAKQICARLCISVSAVQLYLASARRKLTVAT 226
Cdd:COG2909    95 LLERLLALAEAAGRLLLRALALRALGDREEALAALRRRL-----LAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRS 169

                          90
                  ....*....|....
gi 1039509106 227 TSEAVAKATALELI 240
Cdd:COG2909   170 RTEAVARARELGLL 183
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
173-224 1.86e-03

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 38.29  E-value: 1.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1039509106 173 KTADFPQLSRRELQCLQMTANGLLAKQICARLCISVSAVQLYLASARRKLTV 224
Cdd:PRK10403  147 EEDPFSVLTERELDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNV 198
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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