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Conserved domains on  [gi|1053731840|ref|WP_066045153|]
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lysophospholipid acyltransferase family protein [Francisella hispaniensis]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 10787785)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 24-296 3.58e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


:

Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 251.65  E-value: 3.58e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  24 SKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFLSKKRFNK-IE 102
Cdd:COG1560     6 RLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERLRKrVE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 103 FEweegSRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKNFV 182
Cdd:COG1560    86 VE----GLEHLEAALAE-GRGVILLTPHFGNWELAGAALALRGYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDGV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 183 -SVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKCLKKYKIVTGEPF 261
Cdd:COG1560   161 rALLRALRKGGIVGLLPDQDP-----GRKSGVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPL 235

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1053731840 262 E-FTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRY 296
Cdd:COG1560   236 EdFSEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
 
Name Accession Description Interval E-value
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 24-296 3.58e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 251.65  E-value: 3.58e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  24 SKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFLSKKRFNK-IE 102
Cdd:COG1560     6 RLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERLRKrVE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 103 FEweegSRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKNFV 182
Cdd:COG1560    86 VE----GLEHLEAALAE-GRGVILLTPHFGNWELAGAALALRGYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDGV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 183 -SVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKCLKKYKIVTGEPF 261
Cdd:COG1560   161 rALLRALRKGGIVGLLPDQDP-----GRKSGVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPL 235

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1053731840 262 E-FTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRY 296
Cdd:COG1560   236 EdFSEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 8-307 6.41e-66

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 208.73  E-value: 6.41e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   8 PKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAET 87
Cdd:TIGR02207  10 PRYWPTWLGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFESTGMALFET 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  88 TAAWFLSKKRFNKIeFEwEEGsRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQeFSPFTVMYQKNGNDLIEELIKQY 167
Cdd:TIGR02207  90 GMAWFWSDARIKKW-MQ-IEG-LEHLQRAQKQ-GRGVLLVGVHFLTLELGARIFGQ-QQPGIGVYRPHNNPLFDWIQTRG 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 168 REKSLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFG-KLCSTLTVTPWLAQKTGAVVIPAYYVR 246
Cdd:TIGR02207 165 RLRSNKAMIDRKDLRGMIKALKNGERIWYAPDHDY-----GRKSSVFVPFFAvPDAATTTGTSILARLSKCAVVPFTPRR 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 247 EKCLKKYKIVTGEPFEF--TGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPN-GEPQIY 307
Cdd:TIGR02207 240 NEDGSGYRLKIDPPLDDfpGDDEIAAAARMNKIVEKMIMRAPEQYMWLHRRFKTRPDeGESSLY 303
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
8-298 5.95e-58

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 187.94  E-value: 5.95e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   8 PKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAET 87
Cdd:pfam03279  10 PRYWLDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFASVGRAIVET 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  88 TAAWFLSKKRFNKiEFEWEEgsRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQY 167
Cdd:pfam03279  90 GRVWFWPDSRIAK-RFEVIG--LEHIKEALAQ-GRGAILVGPHFGNWDLGGRVLGQQYPGMAVYRPNLKNPLLDWLQTSG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 168 REKSLYKCLDSKN-FVSVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVR 246
Cdd:pfam03279 166 RERFGGRMLPRQNgIKGLIKALRKGEVVWYLPDQDL-----GRKDSVFVPFFGVPAATTTGPAKLALKTKAAVIPVFPIR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 247 EKCLKKYKIVTGEPFEF--TGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRT 298
Cdd:pfam03279 241 NGDGSGYTVIVHPALDLtiTDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 110-297 1.20e-56

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 181.26  E-value: 1.20e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 110 RERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKN-FVSVIKSL 188
Cdd:cd07984     9 LEHLEAALAK-GKGVILLTAHFGNWELAGLALALLGYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRGGgLRELIRAL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 189 KKGYTMWYAPDQDFGLEstgleNSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKClKKYKIVTGEPFEF--TGD 266
Cdd:cd07984    88 KKGEIVGILPDQDPGRK-----GGVFVPFFGRPAATPTGPARLALKTGAPVVPAFAYRLPG-GGYRIEFEPPLENppSED 161

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1053731840 267 SYKDAEMTNKFLEDAVRKYPEQYLWQHRRYR 297
Cdd:cd07984   162 VEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
PRK05646 PRK05646
lipid A biosynthesis lauroyl acyltransferase; Provisional
 6-307 1.65e-54

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235543 [Multi-domain]  Cd Length: 310  Bit Score: 179.62  E-value: 1.65e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   6 FSPKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGA 85
Cdd:PRK05646   11 LHPRFWPLWLGLGLLWLVVQLPYRVLLWLGRALGALMYRLAGSRRRIAARNLELCFPEKSAAERERLLKENFASTGIAFF 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  86 ETTAAWFLSKKRFNKIEFEweEGSrERFEKYHNDPEKkLIILGFHFHCIEIIGRYMGQEFSpFTVMYQKNGNDLIEELIK 165
Cdd:PRK05646   91 EMAMSWWWPKARLARLAHI--EGL-EHLQQAQQEGQG-VILMALHFTTLEIGAALLGQQHT-IDGMYREHKNPVFDFIQR 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 166 QYREKslyKCLDS-----KNFVSVIKSLKKGYTMWYAPDQDFGLEStglenSIFAPFFGKLCSTLTVTPWLAQKTGAVVI 240
Cdd:PRK05646  166 RGRER---HNLDStaierEDVRGMLKLLRAGRAIWYAPDQDYGAKQ-----SIFVPLFGIPAATVTATTKFARLGRARVI 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1053731840 241 PAYYVREKCLKKYKIVTGEPFE-FTGDS-YKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK05646  238 PFTQKRLADGSGYRLVIHPPLEdFPGESeEADCLRINQWVERVVRECPEQYLWAHRRFKSRPEGEPKLY 306
 
Name Accession Description Interval E-value
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 24-296 3.58e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 251.65  E-value: 3.58e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  24 SKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFLSKKRFNK-IE 102
Cdd:COG1560     6 RLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERLRKrVE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 103 FEweegSRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKNFV 182
Cdd:COG1560    86 VE----GLEHLEAALAE-GRGVILLTPHFGNWELAGAALALRGYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDGV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 183 -SVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKCLKKYKIVTGEPF 261
Cdd:COG1560   161 rALLRALRKGGIVGLLPDQDP-----GRKSGVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPL 235

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1053731840 262 E-FTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRY 296
Cdd:COG1560   236 EdFSEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 8-307 6.41e-66

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 208.73  E-value: 6.41e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   8 PKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAET 87
Cdd:TIGR02207  10 PRYWPTWLGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFESTGMALFET 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  88 TAAWFLSKKRFNKIeFEwEEGsRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQeFSPFTVMYQKNGNDLIEELIKQY 167
Cdd:TIGR02207  90 GMAWFWSDARIKKW-MQ-IEG-LEHLQRAQKQ-GRGVLLVGVHFLTLELGARIFGQ-QQPGIGVYRPHNNPLFDWIQTRG 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 168 REKSLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFG-KLCSTLTVTPWLAQKTGAVVIPAYYVR 246
Cdd:TIGR02207 165 RLRSNKAMIDRKDLRGMIKALKNGERIWYAPDHDY-----GRKSSVFVPFFAvPDAATTTGTSILARLSKCAVVPFTPRR 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 247 EKCLKKYKIVTGEPFEF--TGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPN-GEPQIY 307
Cdd:TIGR02207 240 NEDGSGYRLKIDPPLDDfpGDDEIAAAARMNKIVEKMIMRAPEQYMWLHRRFKTRPDeGESSLY 303
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
8-298 5.95e-58

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 187.94  E-value: 5.95e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   8 PKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAET 87
Cdd:pfam03279  10 PRYWLDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFASVGRAIVET 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  88 TAAWFLSKKRFNKiEFEWEEgsRERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQY 167
Cdd:pfam03279  90 GRVWFWPDSRIAK-RFEVIG--LEHIKEALAQ-GRGAILVGPHFGNWDLGGRVLGQQYPGMAVYRPNLKNPLLDWLQTSG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 168 REKSLYKCLDSKN-FVSVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVR 246
Cdd:pfam03279 166 RERFGGRMLPRQNgIKGLIKALRKGEVVWYLPDQDL-----GRKDSVFVPFFGVPAATTTGPAKLALKTKAAVIPVFPIR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 247 EKCLKKYKIVTGEPFEF--TGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRT 298
Cdd:pfam03279 241 NGDGSGYTVIVHPALDLtiTDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 110-297 1.20e-56

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 181.26  E-value: 1.20e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 110 RERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKN-FVSVIKSL 188
Cdd:cd07984     9 LEHLEAALAK-GKGVILLTAHFGNWELAGLALALLGYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRGGgLRELIRAL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 189 KKGYTMWYAPDQDFGLEstgleNSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKClKKYKIVTGEPFEF--TGD 266
Cdd:cd07984    88 KKGEIVGILPDQDPGRK-----GGVFVPFFGRPAATPTGPARLALKTGAPVVPAFAYRLPG-GGYRIEFEPPLENppSED 161

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1053731840 267 SYKDAEMTNKFLEDAVRKYPEQYLWQHRRYR 297
Cdd:cd07984   162 VEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
PRK05646 PRK05646
lipid A biosynthesis lauroyl acyltransferase; Provisional
 6-307 1.65e-54

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235543 [Multi-domain]  Cd Length: 310  Bit Score: 179.62  E-value: 1.65e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   6 FSPKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGA 85
Cdd:PRK05646   11 LHPRFWPLWLGLGLLWLVVQLPYRVLLWLGRALGALMYRLAGSRRRIAARNLELCFPEKSAAERERLLKENFASTGIAFF 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  86 ETTAAWFLSKKRFNKIEFEweEGSrERFEKYHNDPEKkLIILGFHFHCIEIIGRYMGQEFSpFTVMYQKNGNDLIEELIK 165
Cdd:PRK05646   91 EMAMSWWWPKARLARLAHI--EGL-EHLQQAQQEGQG-VILMALHFTTLEIGAALLGQQHT-IDGMYREHKNPVFDFIQR 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 166 QYREKslyKCLDS-----KNFVSVIKSLKKGYTMWYAPDQDFGLEStglenSIFAPFFGKLCSTLTVTPWLAQKTGAVVI 240
Cdd:PRK05646  166 RGRER---HNLDStaierEDVRGMLKLLRAGRAIWYAPDQDYGAKQ-----SIFVPLFGIPAATVTATTKFARLGRARVI 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1053731840 241 PAYYVREKCLKKYKIVTGEPFE-FTGDS-YKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK05646  238 PFTQKRLADGSGYRLVIHPPLEdFPGESeEADCLRINQWVERVVRECPEQYLWAHRRFKSRPEGEPKLY 306
PRK06860 PRK06860
lipid A biosynthesis lauroyl acyltransferase; Provisional
 5-307 2.54e-51

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235880 [Multi-domain]  Cd Length: 309  Bit Score: 171.25  E-value: 2.54e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   5 KFS-----PKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYS 79
Cdd:PRK06860    8 KFSrallhPRYWLTWLGIGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAIVVKNFES 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  80 MVLSGAETTAAWFLSKKRFNK-IEFEWEEGSRERfekyhnDPEKKLIIL-GFHFHCIEIIGRYMGQeFSPFTVMYQKNGN 157
Cdd:PRK06860   88 VGMALIETGMAWFWPDWRIKRwTEVEGLEHIREV------QAQGRGVLLvGVHFLTLELGARIFGM-HNPGIGVYRPNDN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 158 DLIEELIKQYREKSLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFglestGLENSIFAPFFG--KLCSTlTVTPWLAQKT 235
Cdd:PRK06860  161 PLYDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGERIWYAPDHDY-----GPRSSVFVPFFAveQAATT-TGTWMLARMS 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 236 GAVVIPAYYVREKCLKKYKIVTGEP--FEFTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK06860  235 KAAVIPFVPRRKPDGKGYELIILPPedSPPLDDAEATAAWMNKVVEKCILMAPEQYMWLHRRFKTRPEGVPSRY 308
PRK08025 PRK08025
kdo(2)-lipid IV(A) palmitoleoyltransferase;
6-307 8.88e-48

kdo(2)-lipid IV(A) palmitoleoyltransferase;


Pssm-ID: 181200  Cd Length: 305  Bit Score: 162.21  E-value: 8.88e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   6 FSPKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGA 85
Cdd:PRK08025   12 LHPRYWLTWFGLGVLWLLVQLPYPVLCFLGTRIGRMSRPFLKRRESIARKNLELCFPQMSAEEREKMIAENFRSLGMALL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  86 ETTAAWFLSKKRFNKiefeWEEGSRERFEKYHNDPEKKLIILGFHFHCIEIIGRYMGQeFSPFTVMYQKNGNDLIEELIK 165
Cdd:PRK08025   92 ETGMAWFWPDSRVRK----WFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGL-CQPMMATYRPHNNKLMEWVQT 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 166 QYREKSLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFGLEStglenSIFAPFFG-KLCSTLTVTPWLAQKTGAVVIPAYY 244
Cdd:PRK08025  167 RGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKG-----SSFAPFFAvENVATTNGTYVLSRLSGAAMLTVTM 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 245 VREKCLKKYKIVTGEPFE-FTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK08025  242 VRKADYSGYRLFITPEMEgYPTDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLY 305
PRK08733 PRK08733
LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;
7-307 8.55e-44

LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;


Pssm-ID: 181542 [Multi-domain]  Cd Length: 306  Bit Score: 151.59  E-value: 8.55e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   7 SPKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAE 86
Cdd:PRK08733   15 NPKHWPMYLGLAVMVLAARLPWTLQRALGRGVGWVAMRLAGTRRRAAEVNLKLCFPEQDDAWRARLLRDSFDALGVGLFE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  87 TTAAWFLSKKRFN-KIEFEweegSRERFEKYHNDPEKKLIILGfHFHCIEIIGRYMGQeFSPFTVMYQKNGNDLIEELIK 165
Cdd:PRK08733   95 FARAWWGSIDVIRpGVQIE----GLEHLQQLQQQGRGVLLVSG-HFMTLEMCGRLLCD-HVPLAGMYRRHRNPVFEWAVK 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 166 QYREKSLYKCLDSKNFVSVIKSLKKGYTMWYAPDQDFGLESTglensIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYV 245
Cdd:PRK08733  169 RGRLRYATHMFANEDLRATIKHLKRGGFLWYAPDQDMRGKDT-----VFVPFFGHPASTITATHQLARLTGCAVVPYFHR 243

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 246 REKclKKYKIVTGEPFEF--TGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK08733  244 REG--GRYVLKIAPPLADfpSDDVIADTTRVNAAIEDMVREAPDQYLWIHRRFKRQPGGRSDFY 305
PRK06946 PRK06946
lipid A biosynthesis lauroyl acyltransferase; Provisional
 12-307 9.42e-41

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 180770 [Multi-domain]  Cd Length: 293  Bit Score: 143.29  E-value: 9.42e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  12 GIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAW 91
Cdd:PRK06946    5 GTALAIGLLKLLAFLPYGLTARFGDGLGWLLYRIPSRRRRIVHTNLKLCFPDWSDARREELARRHFRHVIRSYVERSVQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  92 FLSKKRFNK-IEFEweegSRERFEKYHNDPEkklIILGFHFHCIEI----IGRYMGqefSPFTVMYQKNGNDLIEELIKQ 166
Cdd:PRK06946   85 FGSEKKLEKlVQVD----SAIDLTDPDGPPT---IFLGLHFVGIEAgsiwLNYSLR---RRVGSLYTPMSNPLLDAIAKA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 167 YREKSlykcldSKNFVS-------VIKSLKKGYTMWYAPDQDFGLEstgleNSIFAPFFGKLCSTLTVTPWLAQKTGAVV 239
Cdd:PRK06946  155 ARGRF------GAEMVSradsarqVLRWLRDGKPVMLGADMDFGLR-----DSTFVPFFGVPACTLTAVSRLARTGGAQV 223

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1053731840 240 IPAY---------YVrekcLKKYKIVTGEPfefTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK06946  224 VPFItevlpdykgYR----LRVFKPWENYP---TGDDDLDARRMNAFLEEQIRLMPEQYYWVHKRFKTRPPGEPSVY 293
lipid_A_msbB TIGR02208
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; This family consists of MsbB ...
 8-307 4.12e-39

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; This family consists of MsbB in E. coli and closely related proteins in other species. MsbB is homologous to HtrB (TIGR02207) and acts immediately after it in the biosynthesis of KDO-2 lipid A (also called Re LPS and Re endotoxin). These two enzymes act after creation of KDO-2 lipid IV-A by addition of the KDO sugars. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274032  Cd Length: 305  Bit Score: 139.55  E-value: 4.12e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   8 PKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMV---LSG 84
Cdd:TIGR02208  12 PKYWGTWLGVFALVLLAFMPAKLRDPIAKVLAKFVGPIAKKPRGRARINLSACFPEKSEAERETIIDNNFATFVqvmLSQ 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  85 AETTAAwflSK----KRFNKIEFEWEEGSRERfekyhndpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLI 160
Cdd:TIGR02208  92 AELAIR---SKahlrRRVNLMGLEHIEAAQAA--------GKPVIFLVPHGWAIDYAGLRLASQGLPMVTMFNNHKNPLF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 161 EELIKQYREKSLYKCLDSKNFV-SVIKSLKKGYTMWYAPDQDFGLEstgleNSIFAPFFGKLCSTLTVTPWLAQKTGAVV 239
Cdd:TIGR02208 161 DWLWNRVRSRFGGHVYAREAGIkALLASLKRGESGYYLPDEDHGPE-----QSVFVPFFATYKATLPVVGRLAKAGNAQV 235

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 240 IPAYYVREKCLKKYKIVTGEPF--EFTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:TIGR02208 236 VPVFPGYNQVTGKFELTVRPAMatELSVDPEQEARAMNKEVEQFILPYPEQYMWILRLLKTRPDGEASIY 305
PRK08943 PRK08943
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated
 7-307 1.12e-36

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated


Pssm-ID: 236355  Cd Length: 314  Bit Score: 133.07  E-value: 1.12e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840   7 SPKNWGIWIVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMV---LS 83
Cdd:PRK08943   20 HPRYWGTWLGIGALAGLALMPPRLRDPLAAKLGRLVGKLAKKARRRARINLSLCFPEKSEAEREAIIDEMFATAPqamLM 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  84 GAETTaawFLSKKRFNK-IEFEWEEGSRErfekyHNDPEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEE 162
Cdd:PRK08943  100 MAELA---LRSPKHLQRrVEWHGLEILEE-----ARANGENVIFLVPHGWAIDIPAMLLASQGQPMAAMFHNQRNPLFDW 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 163 LIKQYREK---SLYKCLDS-KNFvsvIKSLKKGYTMWYAPDQDFGLEstgleNSIFAPFFGKLCSTLTVTPWLAQKTGAV 238
Cdd:PRK08943  172 LWNRVRRRfggRLHAREDGiKPF---ISSVRQGYWGYYLPDEDHGPE-----HSVFVDFFATYKATLPGIGRLAKVCRAR 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1053731840 239 VIPAYYVREKCLKKYKIVTGEPF--EFTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPqIY 307
Cdd:PRK08943  244 VVPLFPVYNGKTHRLDIEIRPPMddLLSADDETIARRMNEEVEQFVGPHPEQYMWILKLLKTRKPGED-LY 313
PRK08706 PRK08706
lipid A biosynthesis lauroyl acyltransferase; Provisional
 26-307 4.05e-35

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 169557 [Multi-domain]  Cd Length: 289  Bit Score: 128.45  E-value: 4.05e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  26 LPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFLSKKRFNKIEfew 105
Cdd:PRK08706   14 LPFALLHKLADLTGLLAYLLVKPRRRIGEINLAKCFPEWDEEKRKTVLKQHFKHMAKLMLEYGLYWYAPAGRLKSLV--- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 106 eegsreRFEKYH-----NDPEKKLIILGFHFHCIEIIGRYMGQEFsPFTVMYQKNGNDLIEELIKQYREK--SLYKCLDS 178
Cdd:PRK08706   91 ------RYRNKHylddaLAAGEKVIILYPHFTAFEMAVYALNQDV-PLISMYSHQKNKILDEQILKGRNRyhNVFLIGRT 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 179 KNFVSVIKSLKKGYTMW-YAPDQDFGLEstgleNSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKC----LKKY 253
Cdd:PRK08706  164 EGLRALVKQFRKSSAPFlYLPDQDFGRN-----DSVFVDFFGIQTATITGLSRIAALANAKVIPAIPVREADntvtLHFY 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 254 KIVTGEPfefTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK08706  239 PAWDSFP---SEDAQADAQRMNRFIEERVREHPEQYFWLHKRFKTRPEGSPDFY 289
PRK08419 PRK08419
lipid A biosynthesis lauroyl acyltransferase; Reviewed
 25-307 3.77e-25

lipid A biosynthesis lauroyl acyltransferase; Reviewed


Pssm-ID: 181420 [Multi-domain]  Cd Length: 298  Bit Score: 102.03  E-value: 3.77e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  25 KLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPE-KSNKEIKKLVKKSYYSMVLSGAETTAAWFLSK-KRFNKIE 102
Cdd:PRK08419   19 KMPHCIFLRLAKALAFIMRYLDKKRRKIAKANLDFCFGEsKSQEEKKRIIKKCYENFAFFGLDFIRNQNTTKeEILNKVT 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 103 FEWEegsrERFEKYHNDpEKKLIILGFHFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKN-F 181
Cdd:PRK08419   99 FINE----ENLLDALKK-KRPIIVTTAHYGYWELFSLALAAYYGAVSIVGRLLKSAPINEMISKRREQFGIELIDKKGaM 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 182 VSVIKSLKKGYTMWYAPDQDfglesTGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAyYVREKCLKKYKIVTGEPF 261
Cdd:PRK08419  174 KELLKALKQGRALGILVDQN-----VVPKEGVEVKFFNKRVTHTTIASILARRYNALIIPV-FIFNDDYSHFTITFFPPI 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1053731840 262 --EFTGDSYKDAE----MTNKFLEDAVRKYPEQYLWQHRRYRtrpNGEPQIY 307
Cdd:PRK08419  248 rsKITDDAEADILeatqAQASACEEMIRKKPDEYFWFHRRFK---SFYPEIY 296
PRK08905 PRK08905
lysophospholipid acyltransferase family protein;
54-304 3.93e-18

lysophospholipid acyltransferase family protein;


Pssm-ID: 236348 [Multi-domain]  Cd Length: 289  Bit Score: 82.73  E-value: 3.93e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  54 RENLKIAFPEkSNKEIKKLVKKSYYSMVLsgaETTAAWF---LSKKRFNKIEFEWEEGSRERFEKyhndpeKKLIILGFH 130
Cdd:PRK08905   40 RANLRQAGGD-PDPAMVKAAAAETGRMIL---ELPYVWFrkpEEIETMVKDDHGWEHVEAALAEG------RGILFLTPH 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 131 FHCIEIIGRYMGQEFsPFTVMYQKNGNDLIEELIKQYREKSLYKCL--DSKNFVSVIKSLKKGYTMWYAPDQdfgLESTG 208
Cdd:PRK08905  110 LGCFEVTARYIAQRF-PLTAMFRPPRKAALRPLMEAGRARGNMRTApaTPQGVRMLVKALRRGEAVGILPDQ---VPSGG 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 209 leNSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKCLKKYKI---VTGEPFefTGDSYKDAEMTNKFLEDAVRKY 285
Cdd:PRK08905  186 --EGVWAPFFGRPAYTMTLVARLAEVTGVPVIFVAGERLPRGRGYRLhlrPVQEPL--PGDKAADAAVINAEIERLIRRF 261

                         250
                  ....*....|....*....
gi 1053731840 286 PEQYLWQHRRYRtRPNGEP 304
Cdd:PRK08905  262 PTQYLWGYNRYK-RPRGAP 279
PRK05645 PRK05645
lysophospholipid acyltransferase;
15-307 9.29e-17

lysophospholipid acyltransferase;


Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 78.79  E-value: 9.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  15 IVVGIMNCGSKLPLFTHKYIVSTIGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFLS 94
Cdd:PRK05645    8 LMVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKLVGQSLMDIGKTLTESACAWIWP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  95 KKRFNKI--EFEWEEGSRERFEKyhndpEKKLIILGFHFHCIEIIGRYMGQEFSPFtVMYQKNGNDLIEELIKQYREKSL 172
Cdd:PRK05645   88 PQKSLELvrEVEGLEVLEQALAS-----GKGVVGITSHLGNWEVLNHFYCSQCKPI-IFYRPPKLKAVDELLRKQRVQLG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 173 YKCLDS--KNFVSVIKSLKKGYTMWYAPDQDFGlESTGlensIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKCL 250
Cdd:PRK05645  162 NRVAPStkEGILSVIKEVRKGGQVGIPADPEPA-ESAG----IFVPFLGTQALTSKFVPNMLAGGKAVGVFLHALRLPDG 236

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1053731840 251 KKYKIVTGEPFE--FTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRPNGEPQIY 307
Cdd:PRK05645  237 SGYKVILEAAPEdmYSTDVEVSAAAMSKVVERYVRAYPSQYMWSMKRFKKRPAGEARWY 295
PRK08734 PRK08734
lauroyl acyltransferase;
36-307 3.65e-14

lauroyl acyltransferase;


Pssm-ID: 181543 [Multi-domain]  Cd Length: 305  Bit Score: 71.45  E-value: 3.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  36 STIGFIIKPFLKSRND---------------IARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFlskkrfnk 100
Cdd:PRK08734   15 ALVGRLPWPLLKRLADllawswrklnaresrVTRRNLELAYPELSPQQRAQLHAQILRSTARQALEVLRTWT-------- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 101 iefEWEEGSRERFEKYHNDP--------EKKLIILGFHFHCIEIIGRYMGqEFSPFTVMYQKNGNDLIEELIKQYREKSL 172
Cdd:PRK08734   87 ---HPPAENLARLRQRHGQElydaalasGRGVIVAAPHFGNWELLNQWLS-ERGPIAIVYRPPESEAVDGFLQLVRGGDN 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 173 YKCLDSKNFV--SVIKSLKKGYTMWYAPDQdfgleSTGLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVR---- 246
Cdd:PRK08734  163 VRQVRAEGPAvrQLFKVLKDGGAVGILPDQ-----QPKMGDGVFAPFFGIPALTMTLVNRLAERTGATVLYGWCERigpd 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1053731840 247 -EKCLkkyKIVTGEPFEFTGDSYKDAEMTNKFLEDAVRKYPEQYLWQHRRYRTRP--NGEPQIY 307
Cdd:PRK08734  238 lEFAL---HVQPADPAVADPDPLRAATALNAGIERIARRDPAQYQWTYKRYTLRPpgSGEHNPY 298
PRK06553 PRK06553
lipid A biosynthesis lauroyl acyltransferase; Provisional
 34-297 4.04e-12

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235827 [Multi-domain]  Cd Length: 308  Bit Score: 65.38  E-value: 4.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  34 IVSTIGfiikPFLkSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTaawFLSK--------KRFNKIEFEw 105
Cdd:PRK06553   50 LARLIG----PLL-PRHRVALDNLRAAFPEKSEAEIEAIALGMWDNLGRLGAEYA---FLDAifdydpeaPEPGRVEVR- 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 106 eegSRERFEKYHNDPeKKLIILGFH---FHCIEIIGRYMGQEfspFTVMYQKNGNDLIEELIKQYREKSLYKCLDSKNFV 182
Cdd:PRK06553  121 ---GIEIFERLRDDG-KPALIFTAHlgnWELLAIAAAAFGLD---VTVLFRPPNNPYAARKVLEARRTTMGGLVPSGAGA 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 183 S--VIKSLKKGYTMWYAPDQDF--GLESTglensifapFFGKLCSTLTVTPWLAQKTGAVVIPAYYVRekcL--KKYKIV 256
Cdd:PRK06553  194 AfaLAGVLERGGHVGMLVDQKFtrGVEVT---------FFGRPVKTNPLLAKLARQYDCPVHGARCIR---LpgGRFRLE 261

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1053731840 257 TGEPFEFTGDSYKD------AEMTNKFLEDAVRKYPEQYLWQHRRYR 297
Cdd:PRK06553  262 LTERVELPRDADGQidvqatMQALTDVVEGWVREYPGQWLWLHRRWR 308
PRK06628 PRK06628
lipid A biosynthesis lauroyl acyltransferase; Provisional
 50-297 2.78e-07

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 102471  Cd Length: 290  Bit Score: 51.08  E-value: 2.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  50 NDIARENLKIAFPEKSnkEIKKLVKKSYYSMVLSGAETTaawFLSKKRFNKIEFEWEEGSRERFEKYHNDPekkLIILGF 129
Cdd:PRK06628   50 NKIARRNIKAVFGDMC--DVEKIIDQTWDNFGRFIGEFT---YVNKMDEAELERRIEIIGIENIKKLEGQP---FLLFSG 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 130 HFHCIEIIGRYMGQEFSPFTVMYQKNGNDLIEELIKQYREKSLYKCL--DSKNFVSVIKSLKKGYTMWYAPDQDfglest 207
Cdd:PRK06628  122 HFANWDISLKILHKFYPKVAVIYRKANNPYVNKLVNESRAGDKLRLIpkGPEGSRALVRAIKESESIVMLVDQK------ 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 208 gLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKclKKYKIVTGEP---FEFTGDSYKDAEMT----NKFLED 280
Cdd:PRK06628  196 -MNDGIEVPFLGHPAMTASAIAKIALQYKYPIIPCQIIRTK--GSYFKVIVHPqlkFEQTGDNKADCYNImlniNQMLGE 272

                         250
                  ....*....|....*..
gi 1053731840 281 AVRKYPEQYLWQHRRYR 297
Cdd:PRK06628  273 WVKQNPAQWFWFHNRWK 289
PRK05906 PRK05906
lipid A biosynthesis lauroyl acyltransferase; Provisional
 38-297 3.18e-07

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 168292 [Multi-domain]  Cd Length: 454  Bit Score: 51.32  E-value: 3.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840  38 IGFIIKPFLKSRNDIARENLKIAFPEKSNKEIKKLVKKSYYSMVLSGAETTAAWFLSKKRFNKIEFEWEEGSRERF---- 113
Cdd:PRK05906   43 LGTLLFYFISDYRKTALTNLALAFPEKSFAERYQIARQSVQHVIITFLELLAVEKLAGHIDELIAIATSEDAPEGFfpee 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 114 --------EKYHNDPEKKLIILgFHFH-------CIEIIGRYMGQEFSpftvmyQKNGNDLIEELIKQYREKSLYKCLDS 178
Cdd:PRK05906  123 vssqqeleHTFSRLDEQEGAIL-FCGHqanwelpFLYITKRYPGLAFA------KPIKNRRLNKKIFSLRESFKGKIVPP 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1053731840 179 KNFV-SVIKSLKKGYTMWYAPDQDFglestgLENSIFAPFFGKLCSTLTVTPWLAQKTGAVVIPAYYVREKclKKYKIVT 257
Cdd:PRK05906  196 KNGInQALRALHQGEVVGIVGDQAL------LSSSYSYPLFGSQAFTTTSPALLAYKTGKPVIAVAIYRKP--NGYLVVP 267

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1053731840 258 GEPFeftgdsYKDAEMTNK------------FLEDAVRKYPEQYLWQHRRYR 297
Cdd:PRK05906  268 SKKF------YANKSLPIKesteqlmdrlmrFLEKGIACKPEQWMWLHKRWK 313
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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