|
Name |
Accession |
Description |
Interval |
E-value |
| recA |
PRK09354 |
recombinase A; Provisional |
1-333 |
0e+00 |
|
recombinase A; Provisional
Pssm-ID: 236476 [Multi-domain] Cd Length: 349 Bit Score: 618.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 1 MDENQKKSLELAIKQIDKAFGKGTLIRLGDKEVIPTEAISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIA 80
Cdd:PRK09354 3 MDEEKQKALEAALKQIEKQFGKGSIMRLGDDAAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 81 EAQKAGGVCAFIDAEHALDVKYARDIGVDTDNLLVSQPDFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEIDGDMDD 160
Cdd:PRK09354 83 EAQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 161 QQVGVQARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMTgYGSPETTTGGNALKFYSSVRLDIRRIATLKQGENSIGN 240
Cdd:PRK09354 163 SHVGLQARLMSQALRKLTGNISKSNTTVIFINQIREKIGVM-FGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 241 RVKVKVVKNKVAAPFKQAEFDIMFGEGISKTGELVDYGVKLDIIDKAGAWFSYGDTKIGQGRENSKVFLRDNPAIAKEIE 320
Cdd:PRK09354 242 RTKVKVVKNKVAPPFKQAEFDIMYGEGISREGELIDLGVELGIIEKSGAWYSYNGEKIGQGRENAKQYLKENPELADEIE 321
|
330
....*....|...
gi 1054581695 321 DKILNSMGINDAI 333
Cdd:PRK09354 322 KKIREKLGLSAAA 334
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
1-332 |
0e+00 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 595.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 1 MDENQKKSLELAIKQIDKAFGKGTLIRLGDKEVIPTEAISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIA 80
Cdd:COG0468 6 ASSEKEKALEAALSQIEKQFGKGSIMRLGDKARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 81 EAQKAGGVCAFIDAEHALDVKYARDIGVDTDNLLVSQPDFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEIDGDMDD 160
Cdd:COG0468 86 EAQKAGGIAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 161 QQVGVQARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMtGYGSPETTTGGNALKFYSSVRLDIRRIATLKQGENSIGN 240
Cdd:COG0468 166 SHVGLQARLMSQALRKLTGAISKSNTTVIFINQLREKIGV-MFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGN 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 241 RVKVKVVKNKVAAPFKQAEFDIMFGEGISKTGELVDYGVKLDIIDKAGAWFSYGDTKIGQGRENSKVFLRDNPAIAKEIE 320
Cdd:COG0468 245 RTRVKVVKNKVAPPFKEAEFDIMYGEGISKEGELLDLAVELGIIEKSGAWYSYGGERLGQGRENAKQFLKENPELAEEIE 324
|
330
....*....|..
gi 1054581695 321 DKILNSMGINDA 332
Cdd:COG0468 325 AKIREKLGLGAV 336
|
|
| tigrfam_recA |
TIGR02012 |
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ... |
4-323 |
0e+00 |
|
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 162659 [Multi-domain] Cd Length: 321 Bit Score: 558.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 4 NQKKSLELAIKQIDKAFGKGTLIRLGDKEVIPTEAISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQ 83
Cdd:TIGR02012 1 DKQKALEAALAQIEKQFGKGSIMRLGEKTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEAQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 84 KAGGVCAFIDAEHALDVKYARDIGVDTDNLLVSQPDFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEIDGDMDDQQV 163
Cdd:TIGR02012 81 KAGGTAAFIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 164 GVQARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMTgYGSPETTTGGNALKFYSSVRLDIRRIATLKQGENSIGNRVK 243
Cdd:TIGR02012 161 GLQARLMSQALRKLTGALSKSNTTAIFINQIREKIGVM-FGNPETTTGGNALKFYASVRLDIRRIGTVKQGEEVVGNRTK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 244 VKVVKNKVAAPFKQAEFDIMFGEGISKTGELVDYGVKLDIIDKAGAWFSYGDTKIGQGRENSKVFLRDNPAIAKEIEDKI 323
Cdd:TIGR02012 240 VKVVKNKVAPPFREAEFDILYGEGISKLGEIIDLAVELDIIKKSGSWYSYGDEKLGQGRENAKAFLKENPELAQEIEKKV 319
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
7-269 |
5.65e-166 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 463.41 E-value: 5.65e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 7 KSLELAIKQIDKAFGKGTLIRLGDKEVIPTEAISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAG 86
Cdd:pfam00154 1 KALEAALKQIEKQFGKGSIMKLGDEKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 87 GVCAFIDAEHALDVKYARDIGVDTDNLLVSQPDFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEIDGDMDDQQVGVQ 166
Cdd:pfam00154 81 GTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 167 ARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMTgYGSPETTTGGNALKFYSSVRLDIRRIATLKQGENSIGNRVKVKV 246
Cdd:pfam00154 161 ARLMSQALRKLTGSISKSNTTVIFINQIREKIGVM-FGNPETTTGGRALKFYASVRLDIRRIGQIKQGEEVIGNKTKVKV 239
|
250 260
....*....|....*....|...
gi 1054581695 247 VKNKVAAPFKQAEFDIMFGEGIS 269
Cdd:pfam00154 240 VKNKVAPPFKEAEFDIMYGEGIS 262
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
37-270 |
2.27e-152 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 427.74 E-value: 2.27e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 37 EAISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHALDVKYARDIGVDTDNLLVS 116
Cdd:cd00983 3 EVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLLVS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 117 QPDFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEIDGDMDDQQVGVQARLMSKALRKITGLLSKMNCTVIFINQIRM 196
Cdd:cd00983 83 QPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQLRE 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1054581695 197 KIGmTGYGSPETTTGGNALKFYSSVRLDIRRIATLKQGENSIGNRVKVKVVKNKVAAPFKQAEFDIMFGEGISK 270
Cdd:cd00983 163 KIG-VMFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPPFKQAEFDILYGEGISR 235
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
4-241 |
1.18e-109 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 337.45 E-value: 1.18e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 4 NQKKSLELAIKQIDKAFGKGTLIRLGDKEVIPTEAISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQ 83
Cdd:PRK09519 6 DREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 84 KAGGVCAFIDAEHALDVKYARDIGVDTDNLLVSQPDFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEIDGDMDDQQV 163
Cdd:PRK09519 86 AAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHV 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1054581695 164 GVQARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMTgYGSPETTTGGNALKFYSSVRLDIRRIATLKQGENSIGNR 241
Cdd:PRK09519 166 GLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVM-FGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNR 242
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
58-227 |
6.96e-55 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 177.93 E-value: 6.96e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 58 GRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHALDVKYARDI-----------GVDTDNLLVSQPDFGEQALE 126
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLVQIleaspsselelAEALSRLLYFRPPDTLAHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 127 IL----ETVIRSGAVDLVVVDSVAALTPKVEIDGDMDDQQVGVQARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMTG 202
Cdd:cd01393 81 ALdslpESLFPPPNTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGGS 160
|
170 180
....*....|....*....|....*
gi 1054581695 203 YGSPETTTGGNALKFYSSVRLDIRR 227
Cdd:cd01393 161 GASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
39-232 |
5.16e-23 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 95.07 E-value: 5.16e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEhALDVKYARDI-----GVDTDNL 113
Cdd:cd01394 1 LSTGSKSLDSLLG-GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTE-GLSPERFQQIagerfESIASNI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 114 LVSQP-DFGEQALEI--LETVIRSGAVDLVVVDSVAALTpKVEidgDMDDQQVgvqARLMSKALRKITGLLSKMNCTVIF 190
Cdd:cd01394 79 IVFEPySFDEQGVAIqeAEKLLKSDKVDLVVVDSATALY-RLE---LGDDSEA---NRELSRQMSKLLSIARKYDIPVVI 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1054581695 191 INQIRMKIGmTGYGSPettTGGNALKFYSSVRLDI------RRIATLK 232
Cdd:cd01394 152 TNQVYSDID-DDRLKP---VGGTLLEHWSKAIIRLeksppgLRRATLE 195
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
252-335 |
2.06e-21 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 95.55 E-value: 2.06e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 252 AAPFKQAEFDIMFGEGISKTGELVDYGVKLDIIDKAGAWFSYGDTKIGQGRENSKVFLRDNPAIAKEIEDKILNSMGINd 331
Cdd:PRK09519 693 SPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIG- 771
|
....
gi 1054581695 332 AIIT 335
Cdd:PRK09519 772 AVVT 775
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
36-232 |
2.36e-18 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 82.60 E-value: 2.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 36 TEAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEhALDVKYARDIGVDT----- 110
Cdd:PRK09361 2 DERLPTGCKMLDELLG-GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTE-GLSPERFKQIAGEDfeell 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 111 DNLLVSQP-DFGEQ--ALEILETVIRSGaVDLVVVDSVAALTpKVEIDGDMDDQqvgvqaRLMSKALRKITGLLS---KM 184
Cdd:PRK09361 80 SNIIIFEPsSFEEQseAIRKAEKLAKEN-VGLIVLDSATSLY-RLELEDEEDNS------KLNRELGRQLTHLLKlarKH 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1054581695 185 NCTVIFINQIRMKIGmTGYGSPettTGGNALKFYSS--VRLDI----RRIATLK 232
Cdd:PRK09361 152 DLAVVITNQVYSDID-SDGLRP---LGGHTLEHWSKtiLRLEKfrngKRRATLE 201
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
39-204 |
1.05e-16 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 78.03 E-value: 1.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHALD--VKYARDIGVDTDNLLVS 116
Cdd:COG0467 2 VPTGIPGLDELLG-GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEqlLRRAESLGLDLEEYIES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 117 -------------QPDFGEQALEILETVIRSGAvDLVVVDSVAALTPKveidgdMDDQQvgvQARLMskaLRKITGLLSK 183
Cdd:COG0467 81 gllriidlspeelGLDLEELLARLREAVEEFGA-KRVVIDSLSGLLLA------LPDPE---RLREF---LHRLLRYLKK 147
|
170 180
....*....|....*....|.
gi 1054581695 184 MNCTVIFINQIRMKIGMTGYG 204
Cdd:COG0467 148 RGVTTLLTSETGGLEDEATEG 168
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
46-231 |
4.60e-16 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 75.92 E-value: 4.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 46 LDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEhALDVKYARDIGVD-----TDNLLVSQP-D 119
Cdd:TIGR02237 1 IDELLG-GGVERGTITQIYGPPGSGKTNICMILAVNAARQGKKVVYIDTE-GLSPERFKQIAEDrperaLSNFIVFEVfD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 120 FGEQALEI--LETVIRSGAVDLVVVDSVAALTpKVEIDGDMDDQQVGVQarlmskalRKITGLLS---KMNCTVIFINQI 194
Cdd:TIGR02237 79 FDEQGVAIqkTSKFIDRDSASLVVVDSFTALY-RLELSDDRISRNRELA--------RQLTLLLSlarKKNLAVVITNQV 149
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1054581695 195 RMKIGmTGYGSPettTGGNALKFYSSV-----RLDIRRIATL 231
Cdd:TIGR02237 150 YTDVN-NGTLRP---LGGHLLEHWSKVilrleKFRGRRLATL 187
|
|
| COG4544 |
COG4544 |
Uncharacterized conserved protein [Function unknown]; |
27-143 |
7.71e-16 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443609 [Multi-domain] Cd Length: 230 Bit Score: 75.74 E-value: 7.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 27 RLGDKEVIPTEAISTGSLGLDLALGVGGLPKGRVIEIYGPE-SSGKTTLTLHAIAEAQKAGGVCAFIDAEHALdvkYA-- 103
Cdd:COG4544 17 RGEGLAAAARAVLPTGFAALDAALPGGGLPRGALHEILGPApGIGELGLLLPLLARLAQAGGPVLWIAPPYDL---YApg 93
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1054581695 104 -RDIGVDTDNLLVSQPDFGEQALEILETVIRSGAVDLVVVD 143
Cdd:COG4544 94 lAAAGLDPERLLLVRARRPADALWAAEEALRSGACGAVVAW 134
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
46-231 |
7.99e-13 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 67.32 E-value: 7.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 46 LDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKA------GGVCAFIDAEHALDVK-------------YARDI 106
Cdd:cd19491 1 LDELLG-GGIPVGGITEIAGESGAGKTQLCLQLALTVQLPrelgglGGGAVYICTESSFPSKrlqqlasslpkryHLEKA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 107 GVDTDNLLVSQ-PDFgEQALEILET----VIRSGAVDLVVVDSVAALtpkVEIDGDMDDQQVGVQARLMSKALRKITGLL 181
Cdd:cd19491 80 KNFLDNIFVEHvADL-ETLEHCLNYqlpaLLERGPIRLVVIDSIAAL---FRSEFDTSRSDLVERAKYLRRLADHLKRLA 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1054581695 182 SKMNCTVIFINQIRMKIGmTGYGSPETTTGGNALKFYSSVRL--DIRRIATL 231
Cdd:cd19491 156 DKYNLAVVVVNQVTDRFD-SSSDASGLGVLDYLSQFSSFSGGvsGNRKVPAL 206
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
47-228 |
4.15e-12 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 64.65 E-value: 4.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 47 DLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEA----QKAG--GVCAFIDAEHALDVKYARDIGVDTD-NLLVSQPD 119
Cdd:cd19493 1 DTALA-GGLPLGAITEITGASGSGKTQFALTLASSAampaRKGGldGGVLYIDTESKFSAERLAEIAEARFpEAFSGFME 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 120 FGEQALEIL----------------------ETVIRSGaVDLVVVDSVAALTPKVeidgdMDDQQVGVQARlmSKALRKI 177
Cdd:cd19493 80 ENERAEEMLkrvavvrvttlaqllerlpnleEHILSSG-VRLVVIDSIAALVRRE-----FGGSDGEVTER--HNALARE 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1054581695 178 TGLLSKM----NCTVIFINQIRMKIGMTGYGSPETTTG-GNALKFYSSVRLDIRRI 228
Cdd:cd19493 152 ASSLKRLaeefRIAVLVTNQATTHFGDAGDGSSGVTAAlGDAWAHAVNTRLRLERC 207
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
39-195 |
5.07e-12 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 64.59 E-value: 5.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAE--------HALDVKYARDIGVDT 110
Cdd:cd01124 1 VKTGIPGLDELLG-GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLFFTFEesperllrNAKSFGWDFDEMEDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 111 DNL-LVSQP------DFGEQALEILETVIRSGAVDLVVVDSVAALTPKVEidgdmddqqvgvQARLMSKALRKITGLLSK 183
Cdd:cd01124 80 GKLiIVDAPpteagrFSLDELLSRILSIIKSFKAKRVVIDSLSGLRRAKE------------DQMRARRIVIALLNELRA 147
|
170
....*....|..
gi 1054581695 184 MNCTVIFINQIR 195
Cdd:cd01124 148 AGVTTIFTSEMR 159
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
39-229 |
5.10e-12 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 64.57 E-value: 5.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLH-AIAEAQKAGGVCAFIDA-EHALDVKY-ARDIGVDTDNLL- 114
Cdd:pfam06745 1 VKTGIPGLDEILK-GGFPEGRVVLITGGPGTGKTIFGLQfLYNGALKYGEPGVFVTLeEPPEDLREnARSFGWDLEKLEe 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 115 ------------------VSQPDFGEQALEILETVIRSGAVDLVVVDSVAALTpkveidGDMDDQQVGVQarlmskaLRK 176
Cdd:pfam06745 80 egklaiidastsgigiaeVEDRFDLEELIERLREAIREIGAKRVVIDSITTLF------YLLKPAVAREI-------LRR 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1054581695 177 ITGLLSKMNCTVIFINQIRMKigmtgygspETTTGGNALKFYSS---VRLDIRRIA 229
Cdd:pfam06745 147 LKRVLKGLGVTAIFTSEKPSG---------EGGIGGYGVEEFIVdgvIRLDLKEIE 193
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
39-227 |
1.02e-11 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 64.09 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTlHAIA-------EAQKAGGVCAFIDAEHALDVKYARDI----G 107
Cdd:cd01123 1 ITTGSKELDKLLG-GGIETGSITEMFGEFRTGKTQLC-HTLAvtcqlpiDRGGGEGKAIYIDTEGTFRPERLRAIaqrfG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 108 VDTD----NLLVSQPDFGEQALEILETV---IRSGAVDLVVVDSVAALTpKVEIDGDMDdqqvgVQARLM--SKALRKIT 178
Cdd:cd01123 79 LDPDdvldNVAYARAFNSDHQTQLLDQAaamMVESRFKLLIVDSATALY-RTDYSGRGE-----LSARQMhlAKFLRMLQ 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1054581695 179 GLLSKMNCTVIFINQIRMKI--GMTGYGSPETTTGGNALKFYSSVRLDIRR 227
Cdd:cd01123 153 RLADEFGVAVVVTNQVVAQVdgAMMFAADPKKPIGGNILAHASTTRLYLRK 203
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
39-227 |
1.04e-11 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 63.92 E-value: 1.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTL--TLHAIA----EAQKAGGVCAFIDAEHALDVKYARDI----GV 108
Cdd:cd19514 1 ISTGSTELDKLLG-GGIESMSITEVFGEFRTGKTQLshTLCVTAqlpgSMGGGGGKVAYIDTEGTFRPDRIRPIaerfGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 109 DT----DNLLVSQPDFGEQALEILETV----IRSGAVDLVVVDSVAALtpkVEID----GDMDDQQvgvqaRLMSKALRK 176
Cdd:cd19514 80 DHdavlDNILYARAYTSEHQMELLDYVaakfHEEAVFRLLIIDSIMAL---FRVDfsgrGELAERQ-----QKLAQMLSR 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1054581695 177 ITGLLSKMNCTVIFINQIRMKIG--MTGYGSPETTTGGNALKFYSSVRLDIRR 227
Cdd:cd19514 152 LQKISEEYNVAVFITNQVTADPGaaMTFQADPKKPIGGHILAHASTTRISLRK 204
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
31-238 |
3.25e-10 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 59.62 E-value: 3.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 31 KEVIpteAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTL--TLHAIAEAQK----AGGVCAFIDAEHALD----V 100
Cdd:pfam08423 14 SELI---QITTGSKELDKLLG-GGIETGSITEIFGEFRTGKTQLchTLCVTCQLPLemggGEGKALYIDTEGTFRperlV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 101 KYARDIGVDTDNLLVSQP-------DFGEQALEILETVIRSGAVDLVVVDSVAALTpKVEID--GDMDDQQvgvqaRLMS 171
Cdd:pfam08423 90 AIAERYGLDPEDVLDNVAyaraynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSgrGELAERQ-----QHLA 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 172 KALRKITGLLSKMNCTVIFINQIRMKIG---MTGYGSPETTTGGNALKFYSSVRLDIRRiatlKQGENSI 238
Cdd:pfam08423 164 KFLRTLQRLADEFGVAVVITNQVVAQVDgaaGMFSGDPKKPIGGHIMAHASTTRLSLRK----GRGEQRI 229
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
7-227 |
3.91e-10 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 60.18 E-value: 3.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 7 KSLELAIKQIDKAFGKGTLIRLGDKEVIpteAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTlHAIAEA---- 82
Cdd:PLN03187 79 KICEAAEKLLNQGFITGSDALLKRKSVV---RITTGSQALDELLG-GGIETRCITEAFGEFRSGKTQLA-HTLCVTtqlp 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 83 QKAGGVC---AFIDAEHALD----VKYARDIGVDT----DNLLVSQPDFGEQ---ALEILETVIRSGAVDLVVVDSVAAL 148
Cdd:PLN03187 154 TEMGGGNgkvAYIDTEGTFRpdriVPIAERFGMDAdavlDNIIYARAYTYEHqynLLLGLAAKMAEEPFRLLIVDSVIAL 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 149 tpkVEID----GDMDDQQVGVqARLMSKaLRKITgllSKMNCTVIFINQIRMKI-GMTGYGSPETTTGGNALKFYSSVRL 223
Cdd:PLN03187 234 ---FRVDftgrGELAERQQKL-AQMLSR-LTKIA---EEFNVAVYMTNQVIADPgGGMFISDPKKPAGGHVLAHAATIRL 305
|
....
gi 1054581695 224 DIRR 227
Cdd:PLN03187 306 MLRK 309
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
57-228 |
4.42e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 54.69 E-value: 4.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 57 KGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHALDVKYARDIGVDTDNLLVSqpDFGEQALEILETVIRSGA 136
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 137 VDLVVVDSVAALTPKVEidgdmddqqvgVQARLMSKALRKITGLLSKMNCTVIFINQirmkigmtgygsPETTTGGNALK 216
Cdd:smart00382 79 PDVLILDEITSLLDAEQ-----------EALLLLLEELRLLLLLKSEKNLTVILTTN------------DEKDLGPALLR 135
|
170
....*....|..
gi 1054581695 217 FYSSVRLDIRRI 228
Cdd:smart00382 136 RRFDRRIVLLLI 147
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
55-191 |
5.13e-09 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 56.83 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 55 LPKGRVIEIYGPESSGKTTLTLH---AIAEAQKAGGV------CAFIDAE----------HALDVKYARDIGVDTDNLLV 115
Cdd:COG3598 10 LPEGGVTLLAGPPGTGKSFLALQlaaAVAAGGPWLGRrvppgkVLYLAAEddrgelrrrlKALGADLGLPFADLDGRLRL 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1054581695 116 --SQPDFG-EQALEILETVIRSGAVDLVVVDSVAALtpkveIDGDMDDqqvgvqARLMSKALRKITGLLSKMNCTVIFI 191
Cdd:COG3598 90 lsLAGDLDdTDDLEALERAIEEEGPDLVVIDPLARV-----FGGDEND------AEEMRAFLNPLDRLAERTGAAVLLV 157
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
39-231 |
2.34e-08 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 53.91 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTlHAIA-------EAQKAGGVCAFIDAEHALD----VKYARDIG 107
Cdd:cd19515 1 ISTGSKELDKLLG-GGIETQAITEVFGEFGSGKTQLC-HQLAvnvqlppEEGGLNGKAVYIDTENTFRperiMQMAKALG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 108 VDTDNLL-------VSQPDFGEQALEILETVIRSG-AVDLVVVDSVAALTpKVEIDGdmdDQQVGVQARLMSKALRKITG 179
Cdd:cd19515 79 LDPDEVLdniyvarAYNSNHQMLLVEKAEDLIKEGnNIKLLIVDSLTSHF-RAEYVG---RGTLAERQQKLNKHLHDLHR 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1054581695 180 LLSKMNCTVIFINQIRMKIGMTgYGSPETTTGGNALKFYSSVRLDIR------RIATL 231
Cdd:cd19515 155 LADLYNIAVLVTNQVMAKPDAF-FGDPTQAIGGHILGHAATFRVYLRkgkggkRIARL 211
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
39-231 |
4.77e-08 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 53.73 E-value: 4.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTlHAIA-------EAQKAGGVCAFIDAE---------------- 95
Cdd:PRK04301 84 ITTGSKELDELLG-GGIETQSITEFYGEFGSGKTQIC-HQLAvnvqlpeEKGGLEGKAVYIDTEgtfrperieqmaealg 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 96 ----HALD-VKYARDIGVDTDNLLVsqpdfgEQALEILEtviRSGAVDLVVVDSVAALTpKVEIDG--DMDDQqvgvQAR 168
Cdd:PRK04301 162 ldpdEVLDnIHVARAYNSDHQMLLA------EKAEELIK---EGENIKLVIVDSLTAHF-RAEYVGrgNLAER----QQK 227
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1054581695 169 LMsKALRKITGLLSKMNCTVIFINQIRMKIGMTgYGSPETTTGGNALKFYSSVRLDIR------RIATL 231
Cdd:PRK04301 228 LN-KHLHDLLRLADLYNAAVVVTNQVMARPDAF-FGDPTQPIGGHILGHTATFRIYLRkskgnkRIARL 294
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
58-199 |
6.14e-08 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 52.74 E-value: 6.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 58 GRVIEIYGPESSGKTTLTLHAIA----------EAQKAGGVCA-FIDAEHALDV--------KYARDIgVDTDNLLVSQP 118
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAArcilpsswggVPLGGLEAAVvFIDTDGRFDIlrlrsileARIRAA-IQAANSSDDEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 119 DFGEQALEILE--TVIR-----------------------SGAVDLVVVDSVAALtpkVEIDgDMDDQQVGVQARLMSKA 173
Cdd:cd19490 80 DVEEIARECLQrlHIFRchsslqllatllslenyllslsaNPELGLLLIDSISAF---YWQD-RFSAELARAAPLLQEAA 155
|
170 180 190
....*....|....*....|....*....|
gi 1054581695 174 LRKITGLLSKM----NCTVIFINQIRMKIG 199
Cdd:cd19490 156 LRAILRELRRLrrrfQLVVIATKQALFPGK 185
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
7-238 |
1.05e-07 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 52.81 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 7 KSLELAIKQIDKAFGKGTLIRLGDKEVIpteAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTL--TLHAIAE--- 81
Cdd:PLN03186 76 KILEAASKLVPLGFTTASQLHAQRQEII---QITTGSRELDKILE-GGIETGSITEIYGEFRTGKTQLchTLCVTCQlpl 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 82 AQKAG-GVCAFIDAEHALD----VKYARDIGVDT----DNLLVSQPDFGEQALEILETVIRSGA---VDLVVVDSVAAL- 148
Cdd:PLN03186 152 DQGGGeGKAMYIDTEGTFRpqrlIQIAERFGLNGadvlENVAYARAYNTDHQSELLLEAASMMAetrFALMIVDSATALy 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 149 TPKVEIDGDMDDQQVgvqarLMSKALRKITGLLSKMNCTVIFINQIRMKI-GMTGYGSPETT-TGGNALKFYSSVRLDIR 226
Cdd:PLN03186 232 RTEFSGRGELSARQM-----HLGKFLRSLQRLADEFGVAVVITNQVVAQVdGSAFFAGPQLKpIGGNIMAHASTTRLALR 306
|
250
....*....|..
gi 1054581695 227 RiatlKQGENSI 238
Cdd:PLN03186 307 K----GRGENRI 314
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
58-231 |
1.28e-07 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 50.69 E-value: 1.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 58 GRVIEIYGPESSGKTTLTLHAIAEAQ---KAGGV---CAFIDAEHALDVKYARDIgvDTDNLLvsqpdfgeQALEILETV 131
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQipkCFGGLageAIYIDTEGSFNIHYFRVH--DYVELL--------ALINSLPKF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 132 IRSGA-VDLVVVDSVAALtpkveIDGDMDDqqVGVQARLMSKALRKITGLLSKMNCTVIFINQIRMKIGMtGYGSPETTT 210
Cdd:cd19492 71 LEDHPkVKLIVVDSIAFP-----FRHDFDD--LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKISE-DGQSQLVPA 142
|
170 180
....*....|....*....|....*.
gi 1054581695 211 GGNALKFYSSVRL-----DIRRIATL 231
Cdd:cd19492 143 LGESWSHACTTRLfltwdEKQRFAHL 168
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
39-238 |
1.74e-07 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 52.31 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTL--TLHAIA----EAQKAGGVCAFIDAEHALD----VKYARDIGV 108
Cdd:PTZ00035 100 ITTGSTQLDKLLG-GGIETGSITELFGEFRTGKTQLchTLCVTCqlpiEQGGGEGKVLYIDTEGTFRperiVQIAERFGL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 109 DT----DNLLVSQPDFGEQALEILETVIRSGAVD---LVVVDSVAALtpkVEID----GDMDDQQvgvqaRLMSKALRKI 177
Cdd:PTZ00035 179 DPedvlDNIAYARAYNHEHQMQLLSQAAAKMAEErfaLLIVDSATAL---FRVDysgrGELAERQ-----QHLGKFLRAL 250
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1054581695 178 TGLLSKMNCTVIFINQIRMKI--GMTGYGSPETTTGGNALKFYSSVRLDIRRiatlKQGENSI 238
Cdd:PTZ00035 251 QKLADEFNVAVVITNQVMADVdgASMFVADPKKPIGGHIIAHASTTRLSLRK----GRGEQRI 309
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
39-238 |
2.05e-07 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 51.16 E-value: 2.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTlHAIA-------EAQKAGGVCAFIDAEH--------ALDVKYA 103
Cdd:cd19513 1 ITTGSKELDKLLG-GGIETGSITELFGEFRTGKTQLC-HTLAvtcqlpiDQGGGEGKALYIDTEGtfrperllAIAERYG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 104 RDIGVDTDNLLVSQPDFGEQALEILetvIRSGAV------DLVVVDSVAALTpKVEIDGDMDdqqvgVQARLM--SKALR 175
Cdd:cd19513 79 LNGEDVLDNVAYARAYNTDHQMQLL---IQASAMmaesryALLIVDSATALY-RTDYSGRGE-----LSARQMhlAKFLR 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1054581695 176 KITGLLSKMNCTVIFINQIRMKI--GMTGYGSPETTTGGNALKFYSSVRLDIRRiatlKQGENSI 238
Cdd:cd19513 150 MLQRLADEFGVAVVITNQVVAQVdgAAMFAGDPKKPIGGNIMAHASTTRLYLRK----GRGETRI 210
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
18-145 |
5.97e-07 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 50.22 E-value: 5.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 18 KAFGKGTLIRLGDKEVIPTEAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHA 97
Cdd:cd01121 43 ASPSPSKPLPLSDVEAEEEERISTGIGELDRVLG-GGLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYVSGEES 121
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1054581695 98 LD-VKY-ARDIGVDTDNLLVsqpdFGEQALEILETVIRSGAVDLVVVDSV 145
Cdd:cd01121 122 LSqIKLrAERLGLGSDNLYL----LAETNLEAILAEIEELKPSLVVIDSI 167
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
57-191 |
1.16e-06 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 48.48 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 57 KGRVIEIYGPESSGKTTLtlhaIAEAQKAggvcAFIDAEHALDVKYARDIGVDTDNLlvSQPDFGEQALEILETVIRSga 136
Cdd:pfam13479 1 KKLKILIYGPSGIGKTTF----AKTLPKP----LFLDTEKGSKALDGDRFPDIVIRD--SWQDFLDAIDELTAAELAD-- 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1054581695 137 VDLVVVDSVAALTPKV------------EIDGDMDDQQVGVQARLMSKALRKitglLSKMNCTVIFI 191
Cdd:pfam13479 69 YKTIVIDTVDWLERLClayickqngkgsSIEDGGYGKGYGELGEEFRRLLDA----LQELGKNVIFT 131
|
|
| KaiC-like_N |
cd19488 |
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
39-148 |
2.46e-06 |
|
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410896 [Multi-domain] Cd Length: 225 Bit Score: 47.73 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFI--------------------DAEHAL 98
Cdd:cd19488 1 ISTGIPGLDDILR-GGLPPRRLYLVEGAPGTGKTTLALQFLLEGAANGETGLYItlseteqelravalshgwslDGIHIF 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1054581695 99 DVKYARDIGVDTDNLLVSQP---DFGEQALEILETVIRsGAVDLVVVDSVAAL 148
Cdd:cd19488 80 ELSPSESALDAAQQYTILHPselELSETTRLIFERVER-LKPSRVVIDSLSEL 131
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
34-199 |
6.10e-06 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 47.95 E-value: 6.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 34 IPTEAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHALD--VKYARDIGVD-- 109
Cdd:PRK09302 250 SSNERISSGVPDLDEMLG-GGFFRGSIILVSGATGTGKTLLASKFAEAACRRGERCLLFAFEESRAqlIRNARSWGIDle 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 110 ---TDNLL---VSQPDFG--EQALEILETVIRSGAVDLVVVDSVAALTPKVEIDgdmddqqvGVQARLMskalrKITGLL 181
Cdd:PRK09302 329 kmeEKGLLkiiCARPESYglEDHLIIIKREIEEFKPSRVAIDPLSALARGGSLN--------EFRQFVI-----RLTDYL 395
|
170
....*....|....*...
gi 1054581695 182 SKMNCTVIFINQIRMKIG 199
Cdd:PRK09302 396 KSEEITGLFTNLTPDFMG 413
|
|
| KaiC_C |
cd19484 |
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ... |
39-149 |
1.21e-05 |
|
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410892 [Multi-domain] Cd Length: 218 Bit Score: 45.78 E-value: 1.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 39 ISTGSLGLDLALGVGGLPKGRVIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDAEHALD--VKYARDIGVD-----TD 111
Cdd:cd19484 1 ISTGIPRLDAMLGGGGFFRGSSILVSGATGTGKTLLAASFADAACRRGERCLYFAFEESPAqlIRNAKSIGIDleqmeRK 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1054581695 112 NLL---VSQPDFG--EQALEILETVIRSGAVDLVVVDSVAALT 149
Cdd:cd19484 81 GLLkiiCARPELYglEDHLIIIKSEINEFKPSRVIVDPLSALA 123
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
7-238 |
2.02e-05 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 45.87 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 7 KSLELAIKQIDKAFGKGTLIRLGDKEVIpteAISTGSLGLDLALGvGGLPKGRVIEIYGPESSGKTTLTlHAIA------ 80
Cdd:TIGR02239 49 KILAEAAKLVPMGFTTATEFHQRRQEVI---QLTTGSKELDKLLG-GGIETGSITEIFGEFRTGKTQLC-HTLAvtcqlp 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 81 EAQKAG-GVCAFIDAE--------------------HALD-VKYARDIGVDTDNLLVSQPdfgeqaleilETVIRSGAVD 138
Cdd:TIGR02239 124 IDQGGGeGKALYIDTEgtfrperllaiaeryglnpeDVLDnVAYARAYNTDHQLQLLQQA----------AAMMSESRFA 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 139 LVVVDSVAALTpKVEIDGdmdDQQVGVQARLMSKALRKITGLLSKMNCTVIFINQIRMKI---GMTGYGSPETTTGGNAL 215
Cdd:TIGR02239 194 LLIVDSATALY-RTDFSG---RGELSARQMHLARFLRSLQRLADEFGVAVVITNQVVAQVdgaGSMFAGDPKKPIGGNIM 269
|
250 260
....*....|....*....|...
gi 1054581695 216 KFYSSVRLDIRRiatlKQGENSI 238
Cdd:TIGR02239 270 AHASTTRLSLRK----GRGEQRI 288
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
55-191 |
1.97e-04 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 41.98 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 55 LPKGRVIEIYGPESSGKTTLTLH-AIAEAQ-----------KAGGVcAFIDAE--------------HALDVKYARDIGV 108
Cdd:pfam13481 30 LPAGGLGLLAGAPGTGKTTLALDlAAAVATgkpwlggprvpEQGKV-LYVSAEgpadelrrrlraagADLDLPARLLFLS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 109 DTDNLLVSQPDFGEQAL-----EILETVIRSGAVDLVVVDSVAALTPkveIDGDMDDqqvgvQARLMSKALRKITGllsK 183
Cdd:pfam13481 109 LVESLPLFFLDRGGPLLdadvdALEAALEEVEDPDLVVIDPLARALG---GDENSNS-----DVGRLVKALDRLAR---R 177
|
....*...
gi 1054581695 184 MNCTVIFI 191
Cdd:pfam13481 178 TGATVLLV 185
|
|
| ATPase_2 |
pfam01637 |
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ... |
60-146 |
2.77e-03 |
|
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.
Pssm-ID: 376582 [Multi-domain] Cd Length: 222 Bit Score: 38.84 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054581695 60 VIEIYGPESSGKTTLTLHAIAEAQKAGGVCAFIDA-----EHALDVKYARDIGVDTDNLLVSQPDFGEQAL------EIL 128
Cdd:pfam01637 22 IYVIYGPEGCGKTALLRESIENLLDLGYYVIYYDPlrryfISKLDRFEEVRRLAEALGIAVPKAELEESKLaflaieLLL 101
|
90
....*....|....*...
gi 1054581695 129 ETVIRSGAVDLVVVDSVA 146
Cdd:pfam01637 102 EALKRRGKKIAIIIDEVQ 119
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
53-82 |
3.13e-03 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 38.39 E-value: 3.13e-03
10 20 30
....*....|....*....|....*....|
gi 1054581695 53 GGLPKGRVIEIYGPESSGKTTLTLHAIAEA 82
Cdd:cd19489 2 GGLRTGEITELVGESSSGKTQLCLTAAANV 31
|
|
| |
