|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-467 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 756.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KHELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLPG 160
Cdd:COG0469 82 PVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 161 VAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVA 240
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 241 RGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIE 320
Cdd:COG0469 242 RGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPVE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 321 AVRTMARIIENTEELGRERI---APLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTP 397
Cdd:COG0469 322 AVETMARIAEEAEKSLDYRRildRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALTP 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 398 ERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKI 467
Cdd:COG0469 402 NERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-473 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 639.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGK 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 82 HELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLPGV 161
Cdd:PRK06247 85 VQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPGT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 162 AVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRImeeEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVAR 241
Cdd:PRK06247 165 VLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKI---IGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVAR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 242 GDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIEA 321
Cdd:PRK06247 242 GDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVEA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 322 VRTMARIIENTEELGRERI---APLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTPE 398
Cdd:PRK06247 322 VRTMARIIRQVERDPTYPPlihAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTPN 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1054825512 399 RQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKIGDEDGG 473
Cdd:PRK06247 402 PETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGEDDVS 476
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-464 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 561.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGK 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 82 HELAEGDIFTITTED--VPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLP 159
Cdd:TIGR01064 81 VKLKKGDKVIITTDDikGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 160 GVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEG-RILPVIAKIEKPQAVENLVEIVAAFDGIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 239 VARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 319 IEAVRTMARIIENTEELGRER-----IAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLL 393
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLtnfndRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054825512 394 AFTPERQVRNVLSLSWGVQSYEVPS-VESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVV 464
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-467 |
1.96e-172 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 493.37 E-value: 1.96e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KH-ELAEGDIFTITTED--VPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPR-VVTRVEVGGPVSNNKGL 156
Cdd:cd00288 81 KDiSLKAGDKFLVTTDPaaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 157 NLPGVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDG 236
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 237 IMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGD 316
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 317 YPIEAVRTMARIIENTE-----ELGRERIAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIP 391
Cdd:cd00288 321 YPVEAVKAMARICLEAEkalshRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 392 LLAFTPERQVRNVLSLSWGVQSYEVPSV-----ESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGeVGSTNSIVVHK 466
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVG-SGSTNTMRILT 479
|
.
gi 1054825512 467 I 467
Cdd:cd00288 480 V 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-333 |
4.69e-141 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 408.68 E-value: 4.69e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KH--ELAEGDIFTITTEDV---PGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGP-RVVTRVEVGGPVSNNK 154
Cdd:pfam00224 81 KKdiELKAGDEMIVSTDAKykgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 155 GLNLPGVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAF 234
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 235 DGIMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSV 314
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330
....*....|....*....
gi 1054825512 315 GDYPIEAVRTMARIIENTE 333
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAE 339
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-467 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 756.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KHELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLPG 160
Cdd:COG0469 82 PVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 161 VAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVA 240
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 241 RGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIE 320
Cdd:COG0469 242 RGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPVE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 321 AVRTMARIIENTEELGRERI---APLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTP 397
Cdd:COG0469 322 AVETMARIAEEAEKSLDYRRildRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALTP 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 398 ERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKI 467
Cdd:COG0469 402 NERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-473 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 639.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGK 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 82 HELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLPGV 161
Cdd:PRK06247 85 VQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPGT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 162 AVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRImeeEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVAR 241
Cdd:PRK06247 165 VLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKI---IGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVAR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 242 GDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIEA 321
Cdd:PRK06247 242 GDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVEA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 322 VRTMARIIENTEELGRERI---APLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTPE 398
Cdd:PRK06247 322 VRTMARIIRQVERDPTYPPlihAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTPN 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1054825512 399 RQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKIGDEDGG 473
Cdd:PRK06247 402 PETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGEDDVS 476
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-464 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 561.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGK 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 82 HELAEGDIFTITTED--VPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLP 159
Cdd:TIGR01064 81 VKLKKGDKVIITTDDikGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 160 GVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEG-RILPVIAKIEKPQAVENLVEIVAAFDGIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 239 VARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 319 IEAVRTMARIIENTEELGRER-----IAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLL 393
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLtnfndRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054825512 394 AFTPERQVRNVLSLSWGVQSYEVPS-VESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVV 464
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-457 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 561.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KHELAEGDIFTITTE-DVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLP 159
Cdd:PRK05826 83 KITLKTGDKFTLDTDqKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 160 GVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRI-LPVIAKIEKPQAVENLVEIVAAFDGIM 238
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPhAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 239 VARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYP 318
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 319 IEAVRTMARIIENTEEL--GRERIAPLGSTPHTRGGAITRAAAE-IGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAF 395
Cdd:PRK05826 323 VEAVEAMARICKGAEKEfsINLSKHRLDRQFDRIDEAIAMSAMYaANHLKGVKAIVALTESGRTARLISRFRPGAPIFAV 402
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1054825512 396 TPERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVG 457
Cdd:PRK05826 403 TRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-478 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 522.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:PRK06354 7 MRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KHELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGP--RVVTRVEVGGPVSNNKGLNL 158
Cdd:PRK06354 87 PIELKTGDEFILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKAdgELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 159 PGVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEE-GRILPVIAKIEKPQAVENLVEIVAAFDGI 237
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHnGKHIPIIAKIEKQEAIDNIDAILELCDGL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 238 MVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDY 317
Cdd:PRK06354 247 MVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGDY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 318 PIEAVRTMARIIENTEE--LGRERIAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAF 395
Cdd:PRK06354 327 PVEAVQTMATIAVRIEKdlPYRDILSKRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPILAV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 396 TPERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKIGDEDG--- 472
Cdd:PRK06354 407 TPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVGESGSTDLMKVHVVGAVVAkgq 486
|
....*.
gi 1054825512 473 GSGRIA 478
Cdd:PRK06354 487 GIGRKS 492
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-467 |
1.96e-172 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 493.37 E-value: 1.96e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KH-ELAEGDIFTITTED--VPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPR-VVTRVEVGGPVSNNKGL 156
Cdd:cd00288 81 KDiSLKAGDKFLVTTDPaaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 157 NLPGVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDG 236
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 237 IMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGD 316
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 317 YPIEAVRTMARIIENTE-----ELGRERIAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIP 391
Cdd:cd00288 321 YPVEAVKAMARICLEAEkalshRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 392 LLAFTPERQVRNVLSLSWGVQSYEVPSV-----ESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGeVGSTNSIVVHK 466
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVG-SGSTNTMRILT 479
|
.
gi 1054825512 467 I 467
Cdd:cd00288 480 V 480
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
1-467 |
2.13e-147 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 429.47 E-value: 2.13e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KH-ELAEGDIFTITTE-DVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNL 158
Cdd:PRK09206 81 NDvSLKAGQTFTFTTDkSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 159 PGVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEE-GRILPVIAKIEKPQAVENLVEIVAAFDGI 237
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHgGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 238 MVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDY 317
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 318 PIEAVRTMARIIENTEELGRERIAPLGSTPHTR-GGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFT 396
Cdd:PRK09206 321 PLEAVSIMATICERTDRVMNSRLESNNDNRKLRiTEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1054825512 397 PERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVgEVGSTNSIVVHKI 467
Cdd:PRK09206 401 TNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGALV-PSGTTNTASVHVL 470
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-333 |
4.69e-141 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 408.68 E-value: 4.69e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KH--ELAEGDIFTITTEDV---PGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGP-RVVTRVEVGGPVSNNK 154
Cdd:pfam00224 81 KKdiELKAGDEMIVSTDAKykgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 155 GLNLPGVAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAF 234
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 235 DGIMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSV 314
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330
....*....|....*....
gi 1054825512 315 GDYPIEAVRTMARIIENTE 333
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAE 339
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-467 |
1.32e-125 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 375.25 E-value: 1.32e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVR-AAAQASGRSVAVLVDLQGPKIRLGRFAEG 80
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVReAAKARPNANLGILLDTKGPEIRTGFLKNH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KH-ELAEGDIFTITTE-DVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNL 158
Cdd:PTZ00066 118 KPiTLKEGQTLKITTDyTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 159 PGVAVSVPAMSDKDEAD-LRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDGI 237
Cdd:PTZ00066 198 PGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDGI 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 238 MVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDY 317
Cdd:PTZ00066 278 MVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGKF 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 318 PIEAVRTMARIIENTE------ELGRERIAPLgSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIP 391
Cdd:PTZ00066 358 PVEAVNIMAKICFEAEtcidyrVLYHAIHLAV-PTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYRPSCT 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1054825512 392 LLAFTPERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKI 467
Cdd:PTZ00066 437 ILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMKVVKI 512
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
3-393 |
2.23e-107 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 328.48 E-value: 2.23e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 3 RAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGKH 82
Cdd:PLN02461 22 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGKP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 83 -ELAEGDIFTITTE-DVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRV--TEVDGPRVVTRVEVGGPVSNNKGLNL 158
Cdd:PLN02461 102 vQLKQGQEITITTDySIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVlsCDVEAGTVRCRCENSAMLGERKNVNL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 159 PGVAVSVPAMSDKDEAD-LRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDGI 237
Cdd:PLN02461 182 PGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESDAF 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 238 MVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDY 317
Cdd:PLN02461 262 MVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAY 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 318 PIEAVRTMARIIENTE----------ELGRERIAPLGSTPHTRGGAItRAAAeigeTVGVKYLVTFTQSGDSARRMSRLR 387
Cdd:PLN02461 342 PELAVKTMARICREAEasldygalfkEIMRSAPLPMSPLESLASSAV-RTAN----KVKASLIVVLTRGGTTARLVAKYR 416
|
....*.
gi 1054825512 388 SSIPLL 393
Cdd:PLN02461 417 PAVPIL 422
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
1-467 |
6.41e-104 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 319.38 E-value: 6.41e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 1 MRRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRF--- 77
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLgga 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 78 AEGKHELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVevggpvsNNKGLN 157
Cdd:PLN02762 104 SSAKAEDGEEWTFTVRKFDGSRPEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKC-------TDPGLL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 158 LPGVAVS--------------VPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEE--GRILPVIAKIEKP 221
Cdd:PLN02762 177 LPRANLTfwrdgslvrernamLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARsrDSDIGVIAKIESL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 222 QAVENLVEIVAAFDGIMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLD 301
Cdd:PLN02762 257 DSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQ 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 302 GADAVMLSGETSVGDYPIEAVRTMARIIENTEELGRE-------RIAPLGSTPHTR-GGAITRAAAEIGETVGVKYLVTF 373
Cdd:PLN02762 337 RADALMLSGESAMGLYPEKALSVLRSVSLRMELWSREekrhealELPQLSSSLSDRiSEEICNSAAKMANNLGVDAIFVY 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 374 TQSGDSARRMSRLRSSIPLLAFTPERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVVAGtpV 453
Cdd:PLN02762 417 TKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMIKSGDLVIAVSD--L 494
|
490
....*....|....
gi 1054825512 454 GEVGSTNSIVVHKI 467
Cdd:PLN02762 495 TPSSMLQSIQVRNV 508
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
7-338 |
1.40e-98 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 300.32 E-value: 1.40e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 7 VCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQasgrSVAVLVDLQGPKIRLGRFAEGKHELAE 86
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDD----SIKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 87 GDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLPGVAVSVP 166
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 167 AMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILP-VIAKIEKPQAVENLVEIVAAFDGIMVARGDLG 245
Cdd:PRK06739 162 AITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPnLIAKIETMEAIENFQDICKEADGIMIARGDLG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 246 VELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIEAVRTM 325
Cdd:PRK06739 242 VELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTL 321
|
330
....*....|...
gi 1054825512 326 ARIIENTEELGRE 338
Cdd:PRK06739 322 RLVSEFAEHVKKD 334
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
2-467 |
3.74e-97 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 304.16 E-value: 3.74e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRA-AAQASGRSVAVLVDLQGPKIRLGRFAEg 80
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEyNAQSKDNVIAIMLDTKGPEVRSGDLPQ- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 81 KHELAEGDIFTITTEDVPGTKELVSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGPVSNNKGLNLPG 160
Cdd:PLN02623 189 PIMLEEGQEFTFTIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVRG 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 161 VAVSVPAMSDKDEADLRWAIQIGADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVA 240
Cdd:PLN02623 269 KSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASDGAMVA 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 241 RGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIE 320
Cdd:PLN02623 349 RGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLK 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 321 AVRTMariieNTEELGRERIAPLGSTPHTRGGAITRAAAE--------IGETVGVKYLVtFTQSGDSARRMSRLRSSIPL 392
Cdd:PLN02623 429 AVKVM-----HTVALRTEATLPEGTTPPNLGQAFKNHMSEmfafhatmMANTLGTSIIV-FTRTGFMAILLSHYRPSGTI 502
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1054825512 393 LAFTPERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTTLRANGLAEVGDYVVVV--AGTPVGEVGSTNSIVVHKI 467
Cdd:PLN02623 503 FAFTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEEVALVqsGRQPIWRSESTHHIQVRKV 579
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
28-448 |
6.31e-95 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 294.65 E-value: 6.31e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 28 MDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGKHELAEGDIFTITTEDV---PGTKELV 104
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAfadKGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 105 STTHKGLPNDARVGDPILIDDGRVLVRV-TEVDGPRVVTRVEVGGPVSNNKGLNLPGVAVSVPAMSDKDEADLRWAIQIG 183
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVqSHEDEQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 184 ADIIALSFVRSAADYDDVRRIMEEEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVARGDLGVELPLEQVPLVQKRAVEL 263
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 264 ARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIEAVRTMARIIENTEELGRE----- 338
Cdd:PTZ00300 241 CNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEyvffn 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 339 RIAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTPERQVRNVLSLSWGVQS--YEV 416
Cdd:PTZ00300 321 SIKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESvfFDA 400
|
410 420 430
....*....|....*....|....*....|....*
gi 1054825512 417 PSVESTDAMVKQVDTTL---RANGLAEVGDYVVVV 448
Cdd:PTZ00300 401 ERLGHDEGKEQRVAMGVgfaKSKGYVQSGDLMVVV 435
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
5-469 |
6.07e-79 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 255.36 E-value: 6.07e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 5 KIVCTIGPVTESAEQIQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFAEGKHEL 84
Cdd:PLN02765 31 KIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPISL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 85 AEGDIFTITT-EDVPGTKELVSTTHKGLPNDARVGDPILI--------DDGRVLVRVTEVDGPRVVTRVE----VGGPVS 151
Cdd:PLN02765 111 KAGNTVTLTPdQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKnsatLAGSLF 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 152 NnkgLNLPGVAVSVPAMSDKDEADLR-WAIQIGADIIALSFVRSAADYDDVRRIMEEEG-RILPVIAKIEKPQAVENLVE 229
Cdd:PLN02765 191 T---LHVSQVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIENVEGLTHFDE 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 230 IVAAFDGIMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVaTQVLESMISAPRPTRAEASDCANAVLDGADAVMLS 309
Cdd:PLN02765 268 ILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILLG 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 310 GETSVGDYPIEAVRTMARIIENTE-----ELGRERIAPLGSTPHTRGGAITRAAAEIGETVGVKYLVTFTQSGDSARRMS 384
Cdd:PLN02765 347 AETLRGLYPVETISTVGRICAEAEkvfnqDLYFKKTVKYVGEPMSHLESIASSAVRAAIKVKASVIIVFTSSGRAARLIA 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 385 RLRSSIPLLAFTPERQVRNVL--SLSWGVQSYEVPSVESTDAMVkqVDTTLRANGLAEVGDYVVVVA---GTPVGEVGST 459
Cdd:PLN02765 427 KYRPTMPVLSVVIPRLKTNQLkwSFTGAFQARQCLIVRGLFPML--ADPRHSAESTSATNESVLKVAldhGKAAGVIKSH 504
|
490
....*....|.
gi 1054825512 460 NSIVV-HKIGD 469
Cdd:PLN02765 505 DRVVVcQKVGD 515
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
2-328 |
1.05e-59 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 203.71 E-value: 1.05e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 2 RRAKIVCTIgPvTESAEQ---IQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFA 78
Cdd:PRK08187 133 RRTRIMVTL-P-SEAADDpdfVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVA 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 79 E--GKHELAEGDIFTITTEDVPGTKEL----VSTTHKGLPNDARVGDPILIDDGRVLVRVTEVDGPRVVTRVEVGGP--- 149
Cdd:PRK08187 211 GplGKTRLYTGDRLALVAQGPPRRIDEehfqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTHARPkgl 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 150 -VSNNKGLNLPGVAVSVPAMSDKDEADLRWAIQiGADIIALSFVRSAADYDDVRRIMEEEG----RILPVIAKIEKPQAV 224
Cdd:PRK08187 291 kLKPEKGLNFPDTALDLPALTEKDRADLDFVAR-HADLVGYSFVQSPGDVEALQAALAARRpddwRKLGLVLKIETPRAV 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 225 ENLVEIVAAFDG-----IMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQVLESMISAPRPTRAEASDCANAv 299
Cdd:PRK08187 370 ANLPELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA- 448
|
330 340
....*....|....*....|....*....
gi 1054825512 300 lDGADAVMLSGetsvGDYPIEAVRTMARI 328
Cdd:PRK08187 449 -ARAECVMLNK----GPYLVEAVTFLDDL 472
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
14-334 |
8.59e-55 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 192.86 E-value: 8.59e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 14 TESAEQ---IQALVDAGMDVARLNRSHGDTDVHRKVYENVRAAAQASGRSVAVLVDLQGPKIRLGRFA------------ 78
Cdd:PRK14725 149 TEAADDpdlVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPIApgprviklrptr 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 --------------------------------------------------------------------------------
Cdd:PRK14725 229 dalgrvltparlwltasespppspppgpvglpvdpewlarlepgdelrftdargkkrkltvtevddegvlaegsqtayla 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 79 ---------------------EGKHELAEGDIFTITTEDVPGTKEL-------VSTThkgLP---NDARVGDPILIDDGR 127
Cdd:PRK14725 309 ngtllrlgrhdstrvgglppvEQKLRLKVGDRLVLTRDDAPGDPAQgdapparISCT---LPeafRAARVGERVWFDDGK 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 128 VLVRVTEVDGPRVVTRVEVGGPVSNN----KGLNLPGVAVSVPAMSDKDEADLRWAIQIgADIIALSFVRSAADYDDVRR 203
Cdd:PRK14725 386 IGAVVVKVEADEVELRITHARPGGSKlkagKGINLPDSHLPLPALTDKDLEDLAFVAKH-ADIVALSFVRSPEDVRLLLD 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 204 IMEEEG-RILPVIAKIEKPQAVENLVEIV------AAFdGIMVARGDLGVELPLEQVPLVQKRAVELARRSAKPVIVATQ 276
Cdd:PRK14725 465 ALEKLGaDDLGVVLKIETRRAFENLPRILleamrhPRF-GVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQ 543
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1054825512 277 VLESMISAPRPTRAEASDCANAVLdgADAVMLSGetsvGDYPIEAVRTMARIIENTEE 334
Cdd:PRK14725 544 VLESLAKKGLPSRAEITDAAMALR--AECVMLNK----GPHIVEAVRVLDDILRRMEE 595
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
264-469 |
3.14e-43 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 155.06 E-value: 3.14e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 264 ARRSAKPVIVATQVLESMISAPRPTRAEASDCANAVLDGADAVMLSGETSVGDYPIEAVRTMARIIENTEE--LGRERIA 341
Cdd:COG3848 2 CNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEdlEYREQRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 342 PLGSTPHTR-GGAITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTPERQVRNVLSLSWGVQSYEVPSVE 420
Cdd:COG3848 82 PRAKESSTTiTDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEESA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1054825512 421 STDAMVKQVDTTLRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVHKIGD 469
Cdd:COG3848 162 STDEMFAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKVHVVGD 210
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
353-465 |
2.62e-35 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 127.21 E-value: 2.62e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 353 AITRAAAEIGETVGVKYLVTFTQSGDSARRMSRLRSSIPLLAFTPERQVRNVLSLSWGVQSYEVPSVESTDAMVKQVDTT 432
Cdd:pfam02887 2 AIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKV 81
|
90 100 110
....*....|....*....|....*....|...
gi 1054825512 433 LRANGLAEVGDYVVVVAGTPVGEVGSTNSIVVH 465
Cdd:pfam02887 82 AKEAGLVKKGDLVVITAGVPFGVSGTTNTLKVI 114
|
|
| CitE |
COG2301 |
Citrate lyase beta subunit [Carbohydrate transport and metabolism]; |
173-255 |
7.12e-04 |
|
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
Pssm-ID: 441876 Cd Length: 288 Bit Score: 41.29 E-value: 7.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054825512 173 EADLRWAIQIGADIIALSFVRSAADYDDVRRIM---EEEGRILPVIAKIEKPQAVENLVEIVAAFDGIMVAR-------G 242
Cdd:COG2301 78 LDDLAALVGAGLDGIVLPKVESAEDVRALAALLtelEAEGGSIPLMALIETARGLLNAAEIAAASPRVEALVfgaedlaA 157
|
90
....*....|...
gi 1054825512 243 DLGVELPLEQVPL 255
Cdd:COG2301 158 DLGARRTRDGDEL 170
|
|
| |
