|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 774.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTSVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLV 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 EELKGLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEK 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 160 LRTNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 240 SNPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 320 VSGITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKR 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420 430
....*....|....*....|....*....|
gi 1055041061 400 VSELTGIRIATFSVGPDRDQTNVLLNVWDA 429
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 747.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 3 SVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLR 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 TNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 242 PVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVS 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 322 GITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVS 401
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIE 400
|
410 420
....*....|....*....|..
gi 1055041061 402 ELTGIRIATFSVGPDRDQTNVL 423
Cdd:COG0104 401 ELLGVPISIVSVGPDREQTIVR 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-420 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 711.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEELK 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 85 GLQERGVS-TENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLRTN 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 164 LEMKNRLFEKFYGvEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSNPV 243
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 244 AGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVSGI 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 324 TDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVSEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*..
gi 1055041061 404 TGIRIATFSVGPDRDQT 420
Cdd:pfam00709 400 LGVPIKIISVGPDREQT 416
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-420 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 678.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 3 SVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGV-STENLRISNRAHVILPYHIYQDKVDEEARgdqkIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLR 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 TNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 242 PVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVS 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 322 GITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVS 401
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIE 396
|
410
....*....|....*....
gi 1055041061 402 ELTGIRIATFSVGPDRDQT 420
Cdd:smart00788 397 ELVGVPVSIISTGPDREQT 415
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-428 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 578.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEELK 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 85 GLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLRTN 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 164 LEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSNPV 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 244 AGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVSGI 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 324 TDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVSEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|....*
gi 1055041061 404 TGIRIATFSVGPDRDQTNVLLNVWD 428
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRKELL 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-420 |
8.85e-162 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 458.12 E-value: 8.85e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 3 SVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGV-STENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADlldkkvfeeklr 161
Cdd:cd03108 82 IEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 tnlemknrlfekfygveplkfedifeafyqygqeiaQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSN 241
Cdd:cd03108 150 ------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSN 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 242 PVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVS 321
Cdd:cd03108 194 TTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRIN 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 322 GITDLALNSIDVltgletvkictayeyngeiiteypatlhaiegckpiyeelpgwtedvtgcktldelpeNARNYVKRVS 401
Cdd:cd03108 274 GLTELALTKLDV----------------------------------------------------------NAQKYIERIE 295
|
410
....*....|....*....
gi 1055041061 402 ELTGIRIATFSVGPDRDQT 420
Cdd:cd03108 296 ELLGVPITYISVGPDREQT 314
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
8.97e-34 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 127.87 E-value: 8.97e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYS-GGDNAGHT-IQFEGETYKLHLIPSGIFY-KEKMSIMGNGMVINPKSLVE 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTyIDDEGRKFVHRMLPNGIVSpPLKQVLIGPGSEIDLEVLRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 82 ELKGLQERGVSTEN-LRISNRAHVILPYHiyqdKVDEEARGDQKIGTTCKGIGPCYIDKVQR----IGIRIADLLDKKVf 156
Cdd:NF038379 83 EIEELEDAGHDVGKrLLIHEQATVIELHK----HVEEEAGPMTKIGSTKKGIGAARAAKIRRnpstLGDAEGDFGEGAV- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 157 eeklrtnlemknrlfekfygveplkfedifeafYQYGQEIAQYVTDTSKILsDVLEEGNKVLFEGAQGVMLDVDHGTYPY 236
Cdd:NF038379 158 ---------------------------------RDQPWEIAERVVDNALYD-FALQAAERIQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 237 VTSSNPVAGGVATGAGVGPSQVN--RVIGVSKAYTSRVGD-----GPFPTEL-FDEIGQQirevgREYGTTTGRPRRVGW 308
Cdd:NF038379 204 CTSRDCTPADFLADAGIPLPNVDafKVVGTARTYPIRVAGwsgnsYPDQGETtWEELGLP-----EELTTVTKKVRRVGT 278
|
330
....*....|....
gi 1055041061 309 FDSVVVRHSRRVSG 322
Cdd:NF038379 279 FSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-429 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 774.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTSVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLV 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 EELKGLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEK 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 160 LRTNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 240 SNPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 320 VSGITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKR 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420 430
....*....|....*....|....*....|
gi 1055041061 400 VSELTGIRIATFSVGPDRDQTNVLLNVWDA 429
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-423 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 747.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 3 SVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLR 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 TNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 242 PVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVS 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 322 GITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVS 401
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIE 400
|
410 420
....*....|....*....|..
gi 1055041061 402 ELTGIRIATFSVGPDRDQTNVL 423
Cdd:COG0104 401 ELLGVPISIVSVGPDREQTIVR 422
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-420 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 711.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEELK 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 85 GLQERGVS-TENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLRTN 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 164 LEMKNRLFEKFYGvEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSNPV 243
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 244 AGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVSGI 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 324 TDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVSEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*..
gi 1055041061 404 TGIRIATFSVGPDRDQT 420
Cdd:pfam00709 400 LGVPIKIISVGPDREQT 416
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-420 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 678.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 3 SVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGV-STENLRISNRAHVILPYHIYQDKVDEEARgdqkIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLR 161
Cdd:smart00788 81 IEELEAKGVdVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 TNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 242 PVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVS 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 322 GITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVS 401
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIE 396
|
410
....*....|....*....
gi 1055041061 402 ELTGIRIATFSVGPDRDQT 420
Cdd:smart00788 397 ELVGVPVSIISTGPDREQT 415
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-428 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 578.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEELK 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 85 GLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLRTN 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 164 LEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSNPV 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 244 AGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVSGI 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 324 TDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKRVSEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|....*
gi 1055041061 404 TGIRIATFSVGPDRDQTNVLLNVWD 428
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRKELL 425
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
4-420 |
9.72e-168 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 477.60 E-value: 9.72e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 4 VVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTI-QFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:PLN02513 5 SAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIyNDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGLFEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGVSTEN-LRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLR 161
Cdd:PLN02513 85 IDGLESNGVSCEGrLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFAEKLR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 TNLEMKNRLFEKF-YGVEPLKFEdiFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSS 240
Cdd:PLN02513 165 ELLADAAARFEGFeYDASMVEEE--VEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFVTSS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 241 NPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRV 320
Cdd:PLN02513 243 NPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYSCQI 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 321 SGITDLALNSIDVLTGLETVKICTAYEY-NGEIITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKR 399
Cdd:PLN02513 323 NGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAYVER 402
|
410 420
....*....|....*....|.
gi 1055041061 400 VSELTGIRIATFSVGPDRDQT 420
Cdd:PLN02513 403 IEELVGVPVHYIGVGPGRDAL 423
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
4-420 |
2.29e-166 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 474.52 E-value: 2.29e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 4 VVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEEL 83
Cdd:PTZ00350 15 VVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLEEI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 84 KGLQERGVS-TENLRISNRAHVILPYHIYQDKVDEEARGD--QKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKL 160
Cdd:PTZ00350 95 EQLTKKGINlLGRLYISDRAHLVFDLHQAIDGIQESEKGKggTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKKY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 161 RTNLEMKNrlfeKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSS 240
Cdd:PTZ00350 175 RKLVEKLQ----EQYNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVTSS 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 241 NPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRV 320
Cdd:PTZ00350 251 NTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQMI 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 321 SGITDLALNSIDVLTGLETVKICTAYEYNGE--IITEYPATLHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVK 398
Cdd:PTZ00350 331 NGFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKYVL 410
|
410 420
....*....|....*....|..
gi 1055041061 399 RVSELTGIRIATFSVGPDRDQT 420
Cdd:PTZ00350 411 FIEELLGVPIVWIGVGPNRENM 432
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-420 |
8.85e-162 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 458.12 E-value: 8.85e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 3 SVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEE 82
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 83 LKGLQERGV-STENLRISNRAHVILPYHIYQDKVDEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADlldkkvfeeklr 161
Cdd:cd03108 82 IEELEKKGIdVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 162 tnlemknrlfekfygveplkfedifeafyqygqeiaQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSN 241
Cdd:cd03108 150 ------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSSN 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 242 PVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVS 321
Cdd:cd03108 194 TTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRIN 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 322 GITDLALNSIDVltgletvkictayeyngeiiteypatlhaiegckpiyeelpgwtedvtgcktldelpeNARNYVKRVS 401
Cdd:cd03108 274 GLTELALTKLDV----------------------------------------------------------NAQKYIERIE 295
|
410
....*....|....*....
gi 1055041061 402 ELTGIRIATFSVGPDRDQT 420
Cdd:cd03108 296 ELLGVPITYISVGPDREQT 314
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-420 |
7.07e-149 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 429.61 E-value: 7.07e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSImGNGMVINPKSLVEELK 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARVLI-GPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 85 GLQERG--VSTENLRISNRAHVILPYHIYQDKVDEEARgDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLRT 162
Cdd:PRK13786 83 MLEKHGvkVDAEKLGIDAKTSIIMPYHIELDGLRESAR-TEKIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 163 NLEMKNRLFeKFYGVEP--LKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSS 240
Cdd:PRK13786 162 LAPQKEKEI-KELGGDPsiVRDEALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTSS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 241 NPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRV 320
Cdd:PRK13786 241 STIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIYL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 321 SGITDLALNSIDVLTGLETVKICTAYEYNGEIItEYPATLHA-IEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVKR 399
Cdd:PRK13786 321 NGYTEIALTKLDVLTGLDPIKICVGYELDGEIL-DYPPELTSdLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVER 399
|
410 420
....*....|....*....|.
gi 1055041061 400 VSELTGIRIATFSVGPDRDQT 420
Cdd:PRK13786 400 LEELMGVPIKYISVGPGREQT 420
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-420 |
8.06e-145 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 419.36 E-value: 8.06e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTSVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLV 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 EELKGLQERGVST-ENLRISNRAHVILPYHIYQDKVDEEARG-DQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKvFEE 158
Cdd:PRK13787 81 EECDRLQKEGFPVkDKLLLSDACHLLFPYHSQIDSARETTSSqEHKIGTTKKGIGICYADKMMRTGLRVGDLLDKS-YKR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 159 KLRTNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVT 238
Cdd:PRK13787 160 RLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 239 SSNPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSR 318
Cdd:PRK13787 240 SSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 319 RVSGITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPAtlHAIEGCKPIYEELPGWTEDVTGCKTLDELPENARNYVK 398
Cdd:PRK13787 320 RINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPS--QGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|..
gi 1055041061 399 RVSELTGIRIATFSVGPDRDQT 420
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDT 419
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-420 |
1.35e-139 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 404.96 E-value: 1.35e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTSVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLV 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 EELKGLQERGVSTEnLRISNRAHVILPYHIYQDkvdeeARGDqKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKL 160
Cdd:PRK13788 81 EERENLRAGGLNPK-LLISERAHLVLPHHKYVD-----GRKN-FVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 161 RTNLEMK-NRLFEKFYGVEplkfEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVTS 239
Cdd:PRK13788 154 ERLLEAKpNSTREAGWDTV----EKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 240 SNPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVG----REYGTTTGRPRRVGWFDSVVVR 315
Cdd:PRK13788 230 SHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 316 HSRRVSGITDLALNSIDVLTGLETVKICTAYEYNGeiiteypatlhaiegcKPIYEELPGWTeDVTGCKTLDELPENARN 395
Cdd:PRK13788 310 YACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPGWG-DLDGVKSREALPKEAQA 372
|
410 420
....*....|....*....|....*
gi 1055041061 396 YVKRVSELTGIRIATFSVGPDRDQT 420
Cdd:PRK13788 373 YLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
1-425 |
2.14e-137 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 401.44 E-value: 2.14e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTsVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFyKEKMSIMGNGMVINPKSLV 80
Cdd:PRK13785 1 MT-VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAV-RGKIGVLGNGCVVNPETLF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 EELKGLQERGVsTENLRISNRAHVILPYHIYQDKVDEEARG--DQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEE 158
Cdd:PRK13785 79 DEIDALRERGL-DPDVRVAERAHVILPYHRVLDGIEEEAKSdsDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 159 KLRTNLEMKNRLFEKFYGV------EPLKFEDIFEAFYQYGQEIAQ--YVTDTSKILSDVLEEGNKVLFEGAQGVMLDVD 230
Cdd:PRK13785 158 RLEYVVPQKRALAEDVYGLdasetpEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDID 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 231 HGTYPYVTSSNPVAGGVATGAGVGPSQVNR--VIGVSKAYTSRVGDGPFPTEL---------------FDEIGQQIREVG 293
Cdd:PRK13785 238 HGNYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 294 REYGTTTGRPRRVGWFDSVVVRHSRRVSGITDLALNSIDVLTGLETVKICTAYEYNGEIITEYPATLHAIEGCKPIYEEL 373
Cdd:PRK13785 318 GEYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSF 397
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1055041061 374 PGWTE---DVTGCKTLDELPENARNYVKRVSELTGIRIATFSVGPDRDQTNVLLN 425
Cdd:PRK13785 398 DGWPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLEN 452
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
5-419 |
1.63e-135 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 394.85 E-value: 1.63e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLVEELK 84
Cdd:PRK13783 4 VIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEELE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 85 GLQER-GVSTENLRISNRAHVILPYHIYQDKVDEEARGDQkIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEEKLRTN 163
Cdd:PRK13783 84 ELKEKfPDYSGRIFISELAHVVLPVHKELDEIIESVRKNA-IGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFLEKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 164 LEMKNRLFEKFYGVEPLkFEDIFEAFyqygQEIAQYVTDTSKILsDVLEEgNKVLFEGAQGVMLDVDHGTYPYVTSSNpV 243
Cdd:PRK13783 163 LSLYKKLYGIEFDVEKM-MEDLLTFY----EKIKDLVVSPVEIK-RILEE-KSVLFEGTQGVLLDLDVGTYPYVTSSN-C 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 244 AGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSRRVSGI 323
Cdd:PRK13783 235 STTGVSAGMGFPVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEVSGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 324 TDLALNSIDVLTGLETVKICTAYEYNGEIITEyPATLHAIEGCKPIYEELPGWtedvtgcKTLDElpENARNYVKRVSEL 403
Cdd:PRK13783 315 DSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGW-------KSLED--KNFLKFVDFIERE 384
|
410
....*....|....*.
gi 1055041061 404 TGIRIATFSVGPDRDQ 419
Cdd:PRK13783 385 TGRKIAYISTGPKIEE 400
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-419 |
4.47e-114 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 340.84 E-value: 4.47e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTSVVVVGTQWGDEGKGKITDFLSKEAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLV 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 EELKGLQERGV--STENLRISNRAHVILPYHIYQDKVdEEARGDQKIGTTCKGIGPCYIDKVQRIGIRIADLLDKKVFEE 158
Cdd:PRK13784 81 EEITRLQAKGIaiSAENLFVSESCTIITSYHKLLDAV-RESNTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 159 KLRTNLEMKNRLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVT 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 239 SSNPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVGREYGTTTGRPRRVGWFDSVVVRHSR 318
Cdd:PRK13784 240 SSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 319 RVSGITDLALNSIDVLTGLETVKICTAYEYNG-EIITEYPAT-LHAIEgckPIYEELPGWTEDVTGCKtlDELPENARNY 396
Cdd:PRK13784 320 KCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGkEIYCAYPGIdLYKVE---PILVEMEPFSIDETVTK--DNMPAALKTY 394
|
410 420
....*....|....*....|...
gi 1055041061 397 VKRVSELTGIRIATFSVGPDRDQ 419
Cdd:PRK13784 395 LKTIENHVGIPISSLAYGPSREQ 417
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-420 |
4.89e-72 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 229.77 E-value: 4.89e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 1 MTSVVVVGTQWGDEGKGKITDFLSK--EAEAIARYSGGDNAGHTIQFEGETYKLHLIPSGIFYKEKMSIMGNGMVINPKS 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLALkdKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 79 LVEELKGLQERGvsteNLRISNRAHVILPYHIYQDKVDEEARgdQKIGTTCKGIGPCYIDKVQRIGiRIAdlldkKVFEE 158
Cdd:PRK04293 81 LLKEVEELNVGG----RVFVDYRCGIIEEKHVEEDRSDEHLS--KKIGSTGTGCGPANADRVLRRL-KLA-----KDVEE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 159 klrtnlemknrlfekfygveplkfedifeafyqygqeIAQYVTDTSKILSDVLEEGNKVLFEGAQGVMLDVDHGTYPYVT 238
Cdd:PRK04293 149 -------------------------------------LEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVT 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 239 SSNPVAGGVATGAGVGPSQVNRVIGVSKAYTSRVGDGPFPTELFDEIGQQIREVgrEYGTTTGRPRRVGWFDSVVVRHSR 318
Cdd:PRK04293 192 SKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRAA 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 319 RVSGITDLALNSIDVLtgletvkictayeyngeiiteYPatlhaiegckpiyeelpgwteDVTGCKTLDELPENARNYVK 398
Cdd:PRK04293 270 RINGATQIAITKLDKL---------------------DK---------------------EAYGVTEYDKLPPEAKKFIE 307
|
410 420
....*....|....*....|..
gi 1055041061 399 RVSELTGIRIATFSVGPDRDQT 420
Cdd:PRK04293 308 EIEEELGVPVTLISTGPELEDT 329
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
5-322 |
8.97e-34 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 127.87 E-value: 8.97e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 5 VVVGTQWGDEGKGKITDFLSKEAEAIARYS-GGDNAGHT-IQFEGETYKLHLIPSGIFY-KEKMSIMGNGMVINPKSLVE 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHTyIDDEGRKFVHRMLPNGIVSpPLKQVLIGPGSEIDLEVLRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 82 ELKGLQERGVSTEN-LRISNRAHVILPYHiyqdKVDEEARGDQKIGTTCKGIGPCYIDKVQR----IGIRIADLLDKKVf 156
Cdd:NF038379 83 EIEELEDAGHDVGKrLLIHEQATVIELHK----HVEEEAGPMTKIGSTKKGIGAARAAKIRRnpstLGDAEGDFGEGAV- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 157 eeklrtnlemknrlfekfygveplkfedifeafYQYGQEIAQYVTDTSKILsDVLEEGNKVLFEGAQGVMLDVDHGTYPY 236
Cdd:NF038379 158 ---------------------------------RDQPWEIAERVVDNALYD-FALQAAERIQIEGTQGYSLGLHAGFYPY 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 237 VTSSNPVAGGVATGAGVGPSQVN--RVIGVSKAYTSRVGD-----GPFPTEL-FDEIGQQirevgREYGTTTGRPRRVGW 308
Cdd:NF038379 204 CTSRDCTPADFLADAGIPLPNVDafKVVGTARTYPIRVAGwsgnsYPDQGETtWEELGLP-----EELTTVTKKVRRVGT 278
|
330
....*....|....
gi 1055041061 309 FDSVVVRHSRRVSG 322
Cdd:NF038379 279 FSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-418 |
1.20e-14 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 75.86 E-value: 1.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 4 VVVVGTQWGDEGKGKITDFLSKE--AEAIARYSGGDNAGHTIQFE-GETYKLHLIPSGIFYKEKMSIMGNGMVINPKSLV 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 81 E-ELKGLQERGVSTENLRISNRAHVILPYHIYQDKVDEEARgdqkiGTTCKGIGPCYIDKVQRIGIRIADLLD-----KK 154
Cdd:PTZ00351 252 EkEIIQLIDAGIDYRDRLFIGNVCIVTPYHKLLDLLGSAAN-----SSTLKGMAPVHGSKVMKRGIRLDHIFNddetlRK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 155 VFEEKLRTN---LEMKN-------RLFEKFYGVEPLKFEDIFEAFYQYGQEIAQYVT----------------DTSKILS 208
Cdd:PTZ00351 327 RLEKDMDTYlglLKVKNlsdadvvRLCREENSDGVVRVPDYVIAFAQAKDKVEFLVKlyrdrvrhnpdfparcDVTYELH 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 209 DVLEEGNKVLFEGAQGVMLDVDHGTYPYVTSSnpvaGGVATGAGVGPSQVN------RVIGVSKAY-TSRVGDG------ 275
Cdd:PTZ00351 407 AAVLRGEKVLLEGPQSYWLSNARTKFWESTTS----ADTTAAGLLAASQLNfqkfksVVLNVHKAPgSSRVGIGacpssf 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 276 -------------------------------------PF------------PTELFDEIGQQIREVGR---------EYG 297
Cdd:PTZ00351 483 vpqdyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYNIGVAMaiasaqhhgECG 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055041061 298 TTTGRPRRVGWFDSVVVRHSRRVSGiTDLALNSIDVLTGLETVKICTAYEY----------------NGEII------TE 355
Cdd:PTZ00351 563 AVTKKPRVCGFFDCVLQHEVNSIQG-PYLTISALDRGDEYDKVGVTIAYVYynpegkqvdvnghvykNGDIIragdpvPS 641
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1055041061 356 YPATLHaiegCKPIYEELPGWTED-VTGCKTLDE--LPENARNYVKRVSELTGIRIATFSVGPDRD 418
Cdd:PTZ00351 642 EPALYH----CHPIVKLIDGWRDNpIAAAKRRRNapLPRGVCELLSTIEYFTNCKILSIGNGPNGD 703
|
|
| |
