|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
21-446 |
4.71e-99 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 303.23 E-value: 4.71e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 21 IISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVR 100
Cdd:cd13138 1 ILKTLLLFALPLLLSNLLQQLYNLVDLLIVGQFLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 101 NVSLQILIFSFITGIILMPVALLSARFFV---PDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMF 177
Cdd:cd13138 81 KAVGTLLVLFLILGIVLTILGLLFAPPILrlmNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 178 VLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLTYMG 257
Cdd:cd13138 161 IACVLNIILDLLFIAVFHMGVAGAALATVIAQAISVLLALYYLRKKKLPFKLSLKDFRFDKEILKEILKIGLPSALQQSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 258 INLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVV 337
Cdd:cd13138 241 VSISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 338 LVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFILLTSSF-- 415
Cdd:cd13138 321 LVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLAYLLSRLtg 400
|
410 420 430
....*....|....*....|....*....|.
gi 1055149658 416 LGYYSVFYGNLVSNFIAGLIFYIMVKKSSWR 446
Cdd:cd13138 401 LGLFGIWLAMPISNILSAIICIIYYRKGRWK 431
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
16-439 |
4.20e-64 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 212.70 E-value: 4.20e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 16 ILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKND 95
Cdd:COG0534 1 LTEGPILKLLLRLALPIILGNLLQSLYGLVDTIFVG-RLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 96 ENGVRNVSLQILIFSFITGIILMPVALLSARFFVP---DNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEAT 172
Cdd:COG0534 80 REEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRllgADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 173 FYRMFVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSM 252
Cdd:COG0534 160 MIIMLIGNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDLRPDRKILKRILRIGLPAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 253 LTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVA 332
Cdd:COG0534 240 LQQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 333 LILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFI-LL 411
Cdd:COG0534 320 LLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAyLL 399
|
410 420
....*....|....*....|....*...
gi 1055149658 412 TSSFLGYYSVFYGNLVSNFIAGLIFYIM 439
Cdd:COG0534 400 AFLGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
13-446 |
8.55e-53 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 183.16 E-value: 8.55e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 13 REMILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNG 92
Cdd:cd13142 1 RENILEGSILRTLLKLAWPIIVSNLLQVAYNLADTFWLG-RLGADAVAAPSISWPLIFLFISLGGGLTVAGTALVAQYTG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 93 KNDENGVRNVSLQILIFSFITGIILMPVALLSARFFVPD----NPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGE 168
Cdd:cd13142 80 AGDYDKANKVAGQTFSFVIILSLILAVLGYILSRPLLLLligaPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 169 PEATFYRMFVLLVLKLIFNSIYLLVF----NMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKEL 244
Cdd:cd13142 160 TKTPMKIMFGSVLLNVILDPLLIFGIgpfpGLGVAGAALATVISRGIAAVIGLYLLFKGRVGLKISLRDLKPDWEWLKKI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 245 IKLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKG 324
Cdd:cd13142 240 FRIGLPSSIEQSARALGFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 325 VLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFL 404
Cdd:cd13142 320 ALLIFLILVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLWVI 399
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1055149658 405 R----YFFILLTSsfLGYYSVFYGNLVSNFIAGLIFYIMVKKSSWR 446
Cdd:cd13142 400 RiplaYLLAYVLG--LGVTGIWIAMAISNIVAALIALAWFKRGTWK 443
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
24-446 |
5.48e-48 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 170.00 E-value: 5.48e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 24 TMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVS 103
Cdd:cd13137 2 RIWSLAWPVILENLLQTLVGLVDVFMVG-RLGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 104 LQILIFSFITGIILMPVALLSARFFV---PDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLL 180
Cdd:cd13137 81 GQSLLLALLLSLPLALLGLLFAEPLLrllGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 181 VLKLIFNsiYLLVF------NMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLT 254
Cdd:cd13137 161 VLNIVLD--YVLIFglwgfpGLGVAGAALATVISRVVGALLLLFLLLRGRLPIKISFKGFRLDRKIIKKLLRIGLPAGLE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 255 YMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALI 334
Cdd:cd13137 239 QLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 335 LVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLR--YFFILLT 412
Cdd:cd13137 319 LGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRlpLAYLLGF 398
|
410 420 430
....*....|....*....|....*....|....
gi 1055149658 413 SSFLGYYSVFYGNLVSNFIAGLIFYIMVKKSSWR 446
Cdd:cd13137 399 VLGLGLTGIWLAMFVDTIVRAILLLYRFRKGKWK 432
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
30-438 |
4.11e-36 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 137.84 E-value: 4.11e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 30 IPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQILIF 109
Cdd:cd12082 2 APLLLSMLLQTLYNLVDTFFLG-RLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 110 SFITGIILMPVALLSAR---FFVPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLLVLKLIF 186
Cdd:cd12082 81 AILLGLLLAALLLFFSPlilSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 187 NSI---YLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLTYMGINLGFF 263
Cdd:cd12082 161 DPLlifGLGPPELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLKPDLELLRRLLRIGLPSAIQNSLLSLGLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 264 LINKEV-VVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVVLVLPT 342
Cdd:cd12082 241 IIVAIVaAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLILLF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 343 SKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRY-FFILLTSSFLGYYSV 421
Cdd:cd12082 321 PEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLpLAYVLAYLGLGLYGI 400
|
410
....*....|....*..
gi 1055149658 422 FYGNLVSNFIAGLIFYI 438
Cdd:cd12082 401 WLALVISLILAALVLLL 417
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
20-441 |
9.38e-34 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 131.48 E-value: 9.38e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 20 NIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGV 99
Cdd:cd13143 1 PIGKLFLKFALPAIIGMLVNGLYNIVDGIFVGHGVGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 100 RNVSLQILIFSFITGIILMPVALLSAR---FFVPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRM 176
Cdd:cd13143 81 NRIFSTALLLSLILGLLLTILGLLFLDpllRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 177 FVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLTYM 256
Cdd:cd13143 161 LIGAVLNIILDPLFIFVLGLGIAGAALATVIAQLISLLLLLLYFFRGKSLLKLSLLRFKLSLKIIKEILALGFPSFLMQL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 257 GINLGFFLINKEVVVYGSDV-LAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALIL 335
Cdd:cd13143 241 SSSVVTIVLNLTLLGYGGDIgVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLVL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 336 VVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFILLTSSF 415
Cdd:cd13143 321 FLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINIVLSGYFQAIGKAKRAALLSLLRQGLFLIPLLLILPRL 400
|
410 420
....*....|....*....|....*.
gi 1055149658 416 LGYYSVFYGNLVSNFIAGLIFYIMVK 441
Cdd:cd13143 401 FGLDGIWLAFPLAEILTLLLALILLK 426
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
28-441 |
5.44e-32 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 126.50 E-value: 5.44e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 28 LTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQIL 107
Cdd:cd13147 14 LSIPMIIAMLLQTLYNLVDAIWVA-GLGADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNAAVHSI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 108 IFSFITGIILMPVALLSARffvpdnPVLK----QDALIYFSLYSLII----PFQFMAAIFNSIKSATGEPEATFYRMFVL 179
Cdd:cd13147 93 LLGLIISIILTIVLLPFLE------PILVlmgaGEVLDLAVDYGRIIflgsIFLIFNNVAYGILRGEGDTKRAMYAMVAG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 180 LVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKF-KLNLREYKFDIVVIKELIKLAIPSMLTYMGI 258
Cdd:cd13147 167 SILNIILDPIFIYTLGLGIAGAAWATVISMLISSLVLLYWFFVKKDTYvSLSLKNFKFDKKIVKDILKVGIPASLEQLIM 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 259 NLGFFLINKEVV-VYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVV 337
Cdd:cd13147 247 SVLMIILNLILViVAGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLKTAYNYSIKLGLIIELIIAI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 338 LVLPTSKYIVALFKPTDQIANIA---IESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFILLTSS 414
Cdd:cd13147 327 LIFIFAPQIAYLFTYSEESAHLApeiVAFLRIMCLFLPFVPFGMMSSSMFQGIGKGLTSLIITILRELIFQVLFAYLFAI 406
|
410 420
....*....|....*....|....*....
gi 1055149658 415 FLGY--YSVFYGNLVSNFIAGLIFYIMVK 441
Cdd:cd13147 407 VLGLglFGVWWGIVLGNAIGSIVGYLWAR 435
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
53-442 |
1.33e-29 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 120.01 E-value: 1.33e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 53 KLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQILIFSFITGIILMPVALLSARF---FV 129
Cdd:cd13145 38 KISTEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRKARRYAAQGLSFGIILAILLTVIGLFAAPPlfrLL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 130 PDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEAtfYR------MFVLLVLKLIFNSIYLLVFNMGIYGAIY 203
Cdd:cd13145 118 GAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKS--YRnfliigFFLNIILDPLFIFGGGGIPAMGVSGIAL 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 204 ASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIA 283
Cdd:cd13145 196 ATIISQFIGMFYLLYKVRKSGIISGCRLRDFIPRLDVYKEILKQGFPASLNMMTIGLGIFVITYFVGQFGDEAVAAYGIA 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 284 TQVTNIcFTMPTC-VATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIE 362
Cdd:cd13145 276 LRIEQI-LLLPTIgLNTAVLSIAGQNFGAKKYDRVRETYKKALKYGFVIMVVATVFLLFFAEPLMSLFTNDPAVIAIGAG 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 363 SLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFILLTSSFLGY--YSVFYGNLVSNFIAGLIFYIMV 440
Cdd:cd13145 355 YLRIDALIFYAYVVLFISVSVLQGLKRPIFALWIGLYRQLVGPALVFWLLVNVLGLgvTGIWWGIFTIVWSAAIIALLYT 434
|
..
gi 1055149658 441 KK 442
Cdd:cd13145 435 RR 436
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
28-442 |
3.20e-29 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 118.87 E-value: 3.20e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 28 LTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQIL 107
Cdd:cd13144 13 MSIPAMISMLFQALYNIVDSIFVA-RLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANKAANNGL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 108 IFSFITGIILMPVALLSARFF---VPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLLVLKL 184
Cdd:cd13144 92 LLALLSYLLFLLLGLFGVKPFfrlFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIAQLIGAIINI 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 185 IFNSI----YLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLTYMGINL 260
Cdd:cd13144 172 ILDPIlifgLFGFPAMGIAGAAIATVIGQILAMFLAFFFLLRKNKDVQPDLRLFRPSLRIIKEIYAVGLPSIIMQAISSV 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 261 GFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVVLVL 340
Cdd:cd13144 252 MVFGLNKILAGFGPTAVAVFGIYFKLQSFVFMPVFGLNNGLIPIVAYNYGAGNKDRIREAIKYAILIAVVIMLAGGLLFQ 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 341 PTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFILLTSSFLGYYS 420
Cdd:cd13144 332 LFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRGVYSLIISVARQLVVLLPLAWLLAKMFGLNG 411
|
410 420
....*....|....*....|..
gi 1055149658 421 VFYGNLVSNFIAGLIFYIMVKK 442
Cdd:cd13144 412 VWWSFPIAEIVSFLLSLLFLKR 433
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
24-449 |
8.56e-27 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 111.82 E-value: 8.56e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 24 TMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVS 103
Cdd:cd13134 4 SLFALAWPIFIELLLQMLLGTIDTFMLS-RYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 104 LQILIFSFITGIILMPVALLSARFFV---PDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLL 180
Cdd:cd13134 83 GVALLFNLLLGLVFSLLLLFFGAELLrlmGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLIMN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 181 VLKLIFNSIYLLVF----NMGIYGAIYASLSAYILTSIWMYYDLFiKKYKFKLNLREY-KFDIVVIKELIKLAIPSMLTY 255
Cdd:cd13134 163 ILNIVGNYLLIFGWfglpKLGVAGVAISTVISRAVGLVLLFILLF-RKLKIRFRLKDLrPFPKKLLKKILKIGLPSAGEE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 256 MGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALIL 335
Cdd:cd13134 242 LSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSLAV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 336 VVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWF----LRYFFILL 411
Cdd:cd13134 322 ALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNIVLIGSLRAAGDARFPVLIGIISMWGisvpLAYLLGIV 401
|
410 420 430
....*....|....*....|....*....|....*...
gi 1055149658 412 TSsfLGYYSVFYGNLVSNFIAGLIFYIMVKKSSWRSNI 449
Cdd:cd13134 402 LG--LGLLGVWIAFAADEWVRGIIMLWRWRSGKWIKKA 437
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
16-442 |
1.18e-26 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 111.24 E-value: 1.18e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 16 ILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKND 95
Cdd:cd13149 2 LTEGSIPRHLIKLTLPMIFGILAMLIFNLTDTFFVG-KLGTKELAAISFTFPVVLFLNSLTIGLGIGASAVISRAIGAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 96 ENGVRNVSLQILIFSFITGIILMPVALLSAR---FFVPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEAT 172
Cdd:cd13149 81 RNKAKRLATDSLILSLLLSVIVSLLGLFTIPplfSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 173 FYRM----FVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTsiwMYYDLFIKKYKFKLNLREY---KFDIVVIKELI 245
Cdd:cd13149 161 SLVMlgaaLVNVILDPILIFGFGPIPGMGIAGAAIATVISRALG---LGAALYFLHYHHRLIDFSEpslKALFRSWKDIL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 246 KLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGV 325
Cdd:cd13149 238 SIGIPAALSNILTPLSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLKISL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 326 LIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLR 405
Cdd:cd13149 318 KFSLIYGAILGIVLALFAGWLASLFSAEPEVIELITLYLLIVPIGYGGLGILIITSASFNALGKPLYSLGLNLIRVFLLY 397
|
410 420 430
....*....|....*....|....*....|....*..
gi 1055149658 406 YFFILLTSSFLGYYSVFYGNLVSNFIAGLIFYIMVKK 442
Cdd:cd13149 398 IPLAYVGSHLLGFAGVFIGALAGNLIAGILAYFIAKK 434
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
19-446 |
6.13e-26 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 109.15 E-value: 6.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 19 GNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSyvqpAINMIIALSQGFgvVALSMIG------QLNG 92
Cdd:cd13140 1 GPILKTLLRLALPIMGTSFIQMAYNLTDMFWVG-RLGSDAVAAVG----TAGFFVWLAYAL--ALLSKIGaqvkvsQSIG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 93 KNDENGVRNVSLQILIFSFITGIILMPVALLSA----RFFVPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGE 168
Cdd:cd13140 74 AKDEKEARKYARNALQLNLLLGILYGLLLLLFAkpliGFFNLGDAEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 169 PEATFYRMFVLLVLKLIFNSIYLLVFN----MGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKEL 244
Cdd:cd13140 154 SKTPFIINAIGLVLNIILDPLLIFGFGpfpaLGVAGAALATVLAQAIVFLLFLYALKKKKGLFLKIRILKRPDRKYIKEI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 245 IKLAIPsmltyMGINLGFF-----LINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKK 319
Cdd:cd13140 234 LKLGLP-----VALQSILFalismILARIIASFGPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 320 IFNKGVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMS-- 397
Cdd:cd13140 309 GYKTALKIASAIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRILGFSQLFMCLEITTTGAFNGLGRTKPPAIISiv 388
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1055149658 398 --FLRIwflrYFFILLTSSFLGYYSVFYGNLVSNFIAGLIFYIMVKKSSWR 446
Cdd:cd13140 389 fnGLRI----PLALLLSPTGLGLNGIWWAISISSILKGIILTIWFLLYKKK 435
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
28-445 |
3.11e-22 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 98.37 E-value: 3.11e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 28 LTIPTFMMAIVQTLIPFSDSLFL----NIKLGNNVAAAVSYVqpainMIIALSQGFGVVALSMIGQLNGKNDENGVRNVS 103
Cdd:cd13133 10 IALPLVLSMLSQTVMGFTDRAFLgrlsEVALAASGPAGVLYF-----AILMLFFGLSSGVQVFVAQYNGAGRYSRIGRVL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 104 LQILIFSFITGIILMPVALLSARFF---VPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLL 180
Cdd:cd13133 85 WQGLYFSLLLAPLLALLSALAAPLLfllLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVANLVMV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 181 VLKLIFNsiYLLVF------NMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNL-REYKFDIVVIKELIKLAIPSML 253
Cdd:cd13133 165 VVNIVLD--YALIFgklgfpAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRRFGLrRAWRFDRELLRRILRLGLPSGL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 254 TYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFtMPTC-VATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVA 332
Cdd:cd13133 243 QFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAF-LPMIgLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALAYM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 333 LILVVLVLPTSKYIVALFKP---TDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWF----LR 405
Cdd:cd13133 322 LLLGILFLLFPELLLSIFTPgadFALIAELAVPLLRFVAAYILFDALALVFAGALRGAGDTRFVMLAELIVAWLyllpPA 401
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1055149658 406 YFFILLTSSFLGYYSVFYGNLvsnFIAGLIFYIMVKKSSW 445
Cdd:cd13133 402 YLLVVLGAGLAGAWTVETVYV---IVLALIFLLRFRSGKW 438
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
31-360 |
8.48e-21 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 93.08 E-value: 8.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 31 PTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQILIFS 110
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVG-HLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 111 FITGIILMPVALLSARF---FVPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLLVLKLIFN 187
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIDPllsLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 188 siYLLVF----NMGIYGAIYASLSAYILTS-IWMYYDLFIKKYKFKlNLREYKFDIVVIKELIKLAIPSMLTYMGINLGF 262
Cdd:TIGR00797 160 --YILIFgkfgFLGIVGAALATVISYWLMFlLLLYYIKKAKKIGLK-WEGLLKPDWEVLKRLLKLGLPIAFRVILESLSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 263 FLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVVLVLPT 342
Cdd:TIGR00797 237 ALLALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILF 316
|
330
....*....|....*...
gi 1055149658 343 SKYIVALFKPTDQIANIA 360
Cdd:TIGR00797 317 REFIARLFTNDPEVLELA 334
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
22-436 |
2.82e-18 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 86.78 E-value: 2.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 22 ISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFgVVALS-MIGQLNGKNDENGVR 100
Cdd:cd13131 2 LRALLRLALPILIAQLAQMAMGFVDTVMAG-RLGADDLAAVALGSSLWFPVFTFGMGL-LLAVTpLVAQAHGAGDRRRIR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 101 NVSLQILIFSFITGIILMPVALLSARF--FVPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFV 178
Cdd:cd13131 80 RAVRQGLWLALLLSLPLMLLLWLAPPIlpLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 179 LLVLKLIFNsiYLLVF------NMGIYGAIYASLSAYILTSIWMYydLFIKKYK----FKLNLREYKFDIVVIKELIKLA 248
Cdd:cd13131 160 ALVLNIPLN--YVLIFgkfglpALGGAGAGLATAIVYWLMFLALA--FYIRRHKrfrrYRLFARFWRPDWARLKELLRLG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 249 IPSMLTY---MGInlgFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGV 325
Cdd:cd13131 236 LPIGLTIffeVSL---FAAVALLMGRLGTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDPADARRAGLVGL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 326 LIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWF-- 403
Cdd:cd13131 313 GLGVGFAALTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYKDTRVPFLLALISYWGig 392
|
410 420 430
....*....|....*....|....*....|....*
gi 1055149658 404 --LRYFFILLTSsfLGYYSVFYGnlvsnFIAGLIF 436
Cdd:cd13131 393 lpLGYLLAFTTG--LGAFGVWIG-----LIIGLAL 420
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
18-446 |
9.41e-18 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 84.97 E-value: 9.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 18 NGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDEN 97
Cdd:cd13139 9 SGSLNRAIFLLAIPMVLEMVMESLFAVVDLYFVS-RLGALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 98 GVRNVSLQILIFSFITGIILMPVALlsarFFVPDNPVL---KQDALIYFSLYSLII----PFQFMAAIFNSIKSATGEPe 170
Cdd:cd13139 88 GAGFAAVQAILLGVALSLILSILGY----FFAEDILSLmgaSPAVIAEGYGYTRIMfggnGFIMLLFLINGIFRGAGDA- 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 171 ATFYRmfvLLVLKLIFNSIY--LLVFN------MGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIK 242
Cdd:cd13139 163 AIAMR---SLWLANGLNIILdpLFIFGlgpipaMGVTGAAIATTIGRSIGVLYQLYHLFKGKGRIQIRRRHLKLDWAIIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 243 ELIKLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTnICFTMPTC-VATTVTTMISINIGVENVEKSKKIF 321
Cdd:cd13139 240 KIIKIAVGGILQFLIASSSWIFLVRIIAEFGSTALAGYTIAIRII-MFALLPAWgLSNAAATLVGQNLGAGQPDRAEKSV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 322 NKGVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRI 401
Cdd:cd13139 319 WRAGKYNMVFLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDTKTPTLINLVGF 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1055149658 402 WFLR--YFFILLTSSFLGYYSVFYGNLVSNFIAGLIFYIMVKKSSWR 446
Cdd:cd13139 399 WLFQipLAYLLARHLNLGPKGVFIAIPIAETVLAIAAIILFRRGKWK 445
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
16-440 |
1.88e-15 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 77.83 E-value: 1.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 16 ILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGNNVA--AAVSYVQPAINMIIALSQGFGVVALSM----IGQ 89
Cdd:cd13146 1 MFSGPISPLLIRLALPILIGQLFQLLYNITDTIWISMIDPSDPAlvGGIGLVFPLGMIFLALGNGIQVGVSSLlaraIGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 90 LNGKNDENGVRNVSLQILIFSFITGIILMPVALLSARFFvPDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGEP 169
Cdd:cd13146 81 QRAKELDQAADSGLALALLAATVIVVLGYIFAEPLLQLL-GAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 170 EATFYRMFVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAI 249
Cdd:cd13146 160 KYMMMAMLIGTVVNIVLDPILIFVFDMGVKGAALATVLAQAISLLYLLYVFLIGKSNVTIHIKLSNISSSVIVEILRVGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 250 PSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGN 329
Cdd:cd13146 240 PQMLLQLISSISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVILGI 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 330 IVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWFLRYFFI 409
Cdd:cd13146 320 VVVLVLVLGYVLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFQAIGKAWPSLLLTLIRHVFLSVPVV 399
|
410 420 430
....*....|....*....|....*....|...
gi 1055149658 410 LLTSSFL--GYYSVFYGNLVSNFIAGLIFYIMV 440
Cdd:cd13146 400 YLLAYVFgkGITGVYFGIVSANFFTALLAMFWG 432
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
28-442 |
4.47e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 67.70 E-value: 4.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 28 LTIPTFMMAIVQTLIPFSDSLFL---NIKLGNNVAAAVSYVQPAINMIIALSQGFGVvalsMIGQLNGKNDENGVRNVSL 104
Cdd:cd13135 6 IAIPLILQNLVSQLQMLVDRAFLgriSIRYYSAVGNVTTPFNTITGFLGSISIGFTI----LGSQSVGAKDIKRINDYAI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 105 QILIFSFITGIILMPVALLSAR----FFVPDNPVLKqDALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLL 180
Cdd:cd13135 82 SSIVYNSIIGVILFLLWLFGARiifvLFGVDGQILG-YSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGIIKN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 181 VLKLIFNsiYLLVF------NMGIYGAIYASLSA-YILTSIWMYYDLFIKKYKFKL-NLREYKFDIVVIKELIKLAIPSM 252
Cdd:cd13135 161 LLNVILD--YVLIFgnfgfpRLGIIGAAIATTIAnVLNLIILVYLCRKIKKLTFKLsNTKVLKANIRPYKFTIKLGLPLG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 253 LTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVA 332
Cdd:cd13135 239 GEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGLLIY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 333 LILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMS-FLRIWFLRYFFILL 411
Cdd:cd13135 319 IAAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIIIILFFKSINIVYGFAIRAIGDTKWMLYTQiIGTIIVVSVALLLI 398
|
410 420 430
....*....|....*....|....*....|.
gi 1055149658 412 TSSFLGYYSVFYGNLVSNFIAGLIFYIMVKK 442
Cdd:cd13135 399 FVFKLGLAGVYITLFIDEIIRAIINFLKYRK 429
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
250-400 |
1.50e-11 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 62.58 E-value: 1.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 250 PSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGN 329
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1055149658 330 IVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLR 400
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIIS 151
|
|
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
18-283 |
7.39e-11 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 64.03 E-value: 7.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 18 NGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKL---GNNVAAAVS-------YVQPAINMIIALSQGFGVVALSMI 87
Cdd:COG5841 228 SKDILKELLRIAIPITLSSLVLPLFQLIDSFTVPRRLqaaGLSASEATSlygilsgMAQPLVNLPTVLATALATSLVPAI 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 88 GQLNGKNDENGVRNVSLQILIFSFITGIilmPVALLSARFFVPDNPVL--KQDALIYFSLYSLIIPFQFMAAIFNSIKSA 165
Cdd:COG5841 308 SEAFAKKDRKLVRRRINQALRLTLLIGL---PAAVGLAVLAEPINTLLfgNPEGGGILAILAPSAIFLSLQQVTTGILQG 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 166 TGEPEATFYRMFVLLVLKLIFNsiYLLVFNMGIYGAIYASLSAYILTSIWMYYDLfIKKYKFKLNLREYkfdivvikeLI 245
Cdd:COG5841 385 LGKQKIPVINLLIGLLVKIILN--YLLVPLFGIYGAALATVIGYLVAAILNLAAL-KKYTGFKLDLRRR---------LL 452
|
250 260 270
....*....|....*....|....*....|....*...
gi 1055149658 246 KLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIA 283
Cdd:COG5841 453 KPLLASLIMGIVVLLLYRLLSLFLPESRLGALLATLIA 490
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
31-187 |
3.01e-10 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 58.73 E-value: 3.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 31 PTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQILIFS 110
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVG-HLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 111 FITGIILMPVALLS----ARFFVPDNPVLKQdALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLLVLKLIF 186
Cdd:pfam01554 80 LLLSLPIALLVLLFsepiLSLFGQDEEVLAL-AKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPL 158
|
.
gi 1055149658 187 N 187
Cdd:pfam01554 159 N 159
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
12-328 |
3.20e-10 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 61.90 E-value: 3.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 12 RREMILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQG-FGVVALSMIGQL 90
Cdd:cd13148 1 RTRALLTAPILPTLLRLALPNILALLVQTLVGLAETYFVG-QLGTDALAGVALVFPLLMLTQMMSNGaMGGGVSSAIARA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 91 NGKNDENGVRNVSLQILIFSFITGIILMPVALLSARFFVP----DNPVLKQD---ALIYFSLYSLIIPFQFMAAIFNSIK 163
Cdd:cd13148 80 LGAGDRERAEALVWHALVIALAGGLVFSLLFLLFGPALYRllggRGEALDAAlaySNVLFSGAILIWLVNLLAAALRGTG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 164 SATGEPEATFYRMFVLLVLK--LIFNSIYLLvfNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVI 241
Cdd:cd13148 160 NMRVPALVTLVGAVVQIPLSpgLILGWGPLP--RLGVAGAAVAAVLYYALAALVLLRYLASGRSRLRLRLRALRLERRLF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 242 KELIKLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIF 321
Cdd:cd13148 238 RDILRVGLLAALSPLQTNLTVLLLTGLVGRFGTAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARARRIA 317
|
....*..
gi 1055149658 322 NKGVLIG 328
Cdd:cd13148 318 WTGALMA 324
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
242-444 |
5.07e-10 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 60.99 E-value: 5.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 242 KELIKLAIPSMLTymgiNLGFFLIN----KEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKS 317
Cdd:cd13137 1 RRIWSLAWPVILE----NLLQTLVGlvdvFMVGRLGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 318 KKIFNKGVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPL--- 394
Cdd:cd13137 77 RRALGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMyim 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1055149658 395 -IMSFLRIwFLRYFFILLTSSF--LGYYSVFYGNLVSNFIAGLI-FYIMVKKSS 444
Cdd:cd13137 157 iIVNVLNI-VLDYVLIFGLWGFpgLGVAGAALATVISRVVGALLlLFLLLRGRL 209
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
19-401 |
1.47e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 59.64 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 19 GNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENG 98
Cdd:cd13141 7 GSIPKHIISMALPIAIGMIIQTLYFLVDLYFVG-QLGDAALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRKDQGE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 99 VRNVSLQILIFSFITGIILMPVALLSARFF----VPDNPVLKQdALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEATFY 174
Cdd:cd13141 86 ANAVFNQSLLLAAVLGLVVLVLGYLFGRLYletlAADAATVEA-ATTYLYWFIPSLALQFILTVLGAALRGTGIVKPFMV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 175 RMFVLLVLKLIFNSIylLVFN------MGIYGAIYASLSAYILTSIWM-YYDLFIKKYkFKLNLREYKFDIVVIKELIKL 247
Cdd:cd13141 165 IQILAVLLNIILAPI--LITGwgtgraLGVAGAGLASSISVAIAVVLLlYYFLRLEKY-LRLDLALWRPDLPTWKRLLKI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 248 AIPS----MLTYMGINLGFFLINkevvVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNK 323
Cdd:cd13141 242 GLPSggefLLTFVYMAVIYWALR----PFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRI 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1055149658 324 GVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRI 401
Cdd:cd13141 318 TAILTTALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSWNFVAAGLVFTCSGMFQALGNTWPSLLSSASRL 395
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
1-220 |
1.62e-09 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 59.40 E-value: 1.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 1 MRKIFNKNLDERREMILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGN----NVAAAVSY------VQPAIN 70
Cdd:cd13124 202 RRELKRLLRKSPRSKISTKEILKELLSYAIPITLSSLILPLLQLIDSFTVPRRLQAaglsESEATALYgiltgrAQPLVQ 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 71 MIIALSQGFGVVALSMIGQLNGKNDENGVRNVSLQILIFSFITGIilmPVALLSARFFVPDNPVLKQDALIYFSL--YSL 148
Cdd:cd13124 282 LPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRLTLLIGL---PAAVGLAVLAEPINTLLFGDSEGGLILqiLAP 358
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1055149658 149 IIPFQFMAAIFNSIKSATGEPEATFYRMFVLLVLKLIFNsiYLLVFNMGIYGAIYASLSAYILTSIWMYYDL 220
Cdd:cd13124 359 SILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLN--YVLIPIFGIYGAAIATVIGFLVAALLNLRAL 428
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
12-218 |
1.84e-09 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 59.39 E-value: 1.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 12 RREMILNGNIISTMIFLTIPTFMMaivQTLIPFSDSLFLNI--KLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQ 89
Cdd:COG0534 218 LRDLRPDRKILKRILRIGLPAGLQ---QLAESLGFLVLNALvaRLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQ 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 90 LNGKNDENGVRNVSLQILIFSFITGIILMPVALLSARFFVP---DNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSAT 166
Cdd:COG0534 295 NLGAGDYDRARRAARLALLLALGIGLLLALLLFLFPEPIIGlftDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGA 374
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1055149658 167 GEPEATFYRMFVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYY 218
Cdd:COG0534 375 GDTRFPMIISLLRLWLVRLPLAYLLAFLGLGLTGVWLALPIGEVLRALLLLL 426
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
93-441 |
6.78e-09 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 57.55 E-value: 6.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 93 KNDENGVRNVSLQILIFSFITGIILMPVALLSARFFVPDNPVLKqdalIYFSLYSLIIPFQFMAAIFNSIKSATGEPEAT 172
Cdd:cd13128 66 RYRKEKIREIISTSLVLKLILGILALLLLFLFAFLIAFYDPELV----LLLYILALSLPFSALNSLFRGIFQGFEKMKYI 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 173 FYRMFVLLVLKLIFnSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLnlreYKFDIVVIKELIKLAIPSM 252
Cdd:cd13128 142 VIARIIESVLSLIL-ALILVLLGGGLIGFALAYLIASVLSAILLLYIYRKKILLPKF----FSFDLKLAKELLRFSIPLA 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 253 LTYMGIN---------LGFFLINKEVVVYgsdvlaglAIATQVTNICFTMPTCVATTVTTMISiNIGVENVEKSKKIFNK 323
Cdd:cd13128 217 LSGIFSLiytridtimLGYFLGDAAVGIY--------NAAYRIAELLLFIPSAISTALFPRIS-ELYKNDKDELKKLLKK 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 324 GVLIGNIVALILVVLVLPTSKYIVALFKPTDQIAniAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIWF 403
Cdd:cd13128 288 SFKYLFLISLPIAIGLFLFAEPIITLLFGEEYLP--AALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALL 365
|
330 340 350
....*....|....*....|....*....|....*...
gi 1055149658 404 LRYFFILLTSSFlGYYSVFYGNLVSNFIAGLIFYIMVK 441
Cdd:cd13128 366 NVILNLLLIPKY-GIIGAAIATLISEFIIFILLLYLLK 402
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
16-217 |
1.91e-07 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 53.03 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 16 ILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKND 95
Cdd:COG2244 166 LLGLGLWGLVLKYSLPLLLSGLLGLLLTNLDRLLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGD 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 96 ENGVRNVSLQILIFSFITGIILMPVALLSARFFVPdnPVLKQD---ALIYFSLYSLIIPFQFMAAIFNSIKSATGEPEAT 172
Cdd:COG2244 246 REELRRLYRKALRLLLLLGLPLALGLALLAPPLLS--LLFGPEyaeAAPVLPILALGALFLALSGVLSNLLLALGRTRLL 323
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1055149658 173 FYRMFVLLVLKLIFNsiYLLVFNMGIYGAIYASLSAYILTSIWMY 217
Cdd:COG2244 324 LIISLIGAVLNLVLN--LLLIPRYGLVGAAIATLLSYLVLLLLLL 366
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
85-290 |
3.63e-07 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 52.18 E-value: 3.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 85 SMIGQLNGKNDENGVRNVSLQILIFSFITGIILM----PVALLSARFFVPDNPVLKQdALIYFSLYSLIIPFQFMAAIFN 160
Cdd:cd13136 65 GLVAQALGAGDREEAIALLVRALLLALAIGLLLIllqsPLLALALLLLGASAAVAAL-ARQYLRIRILGAPAVLLNYVAT 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 161 SIKSATGEPEATFYRMFVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVV 240
Cdd:cd13136 144 GWFRGLQDTRTPLILQIVGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSRRLPSKAA 223
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1055149658 241 IKELIKLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNIC 290
Cdd:cd13136 224 LKRLFKLNRDIFIRTLALLAAFLFFTALAARLGDVILAANQILLQFWLLS 273
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
242-451 |
1.10e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 50.58 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 242 KELIKLAIP----SMLTYMGINLGFFLINKevvvYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKS 317
Cdd:cd13134 3 LSLFALAWPifieLLLQMLLGTIDTFMLSR----YSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 318 KKIFNKGVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYP---- 393
Cdd:cd13134 79 RQIAGVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPmyvs 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1055149658 394 LIMSFLRIwFLRYFFILLTSSF--LGYYSVFYGNLVSNFIA-GLIFYIMVKKSSWRSNINY 451
Cdd:cd13134 159 LIMNILNI-VGNYLLIFGWFGLpkLGVAGVAISTVISRAVGlVLLFILLFRKLKIRFRLKD 218
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
250-442 |
2.14e-06 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 49.55 E-value: 2.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 250 PSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGN 329
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 330 IVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPL----IMSFLRIwFLR 405
Cdd:TIGR00797 81 LLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMyitlIGNVINI-ILN 159
|
170 180 190
....*....|....*....|....*....|....*..
gi 1055149658 406 YFFILLTSSFLGYYSVFYGNLVSNFIAGLIFYIMVKK 442
Cdd:TIGR00797 160 YILIFGKFGFLGIVGAALATVISYWLMFLLLLYYIKK 196
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
248-446 |
5.19e-06 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 48.47 E-value: 5.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 248 AIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLI 327
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 328 GNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRT----IYPLIMSFLRIWF 403
Cdd:cd12082 81 AILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTrtamIISVLSNLLNILL 160
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1055149658 404 LRYFFILLTSSFLGYYSVFYGNLVSNFIAGLIFYIMVKKSSWR 446
Cdd:cd12082 161 DPLLIFGLGPPELGIAGAALATVISYVIGALLLLIYLRKGKKI 203
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
3-220 |
7.86e-06 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 47.92 E-value: 7.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 3 KIFNKNLDERREMILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGNNVAAAVSYVQPAINMIIALSQGFGVV 82
Cdd:cd13128 186 YIYRKKILLPKFFSFDLKLAKELLRFSIPLALSGIFSLIYTRIDTIMLGYFLGDAAVGIYNAAYRIAELLLFIPSAISTA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 83 ALSMIGQLNGKNDENGVRNVSLQILIFSFITGIILMPVALLSAR----FFVPDNPvlkqDALIYFSLYSLIIPFQFMAAI 158
Cdd:cd13128 266 LFPRISELYKNDKDELKKLLKKSFKYLFLISLPIAIGLFLFAEPiitlLFGEEYL----PAALVLQILAWGFLFIFLNGI 341
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1055149658 159 FNSIKSATGEPEATFYRMFVLLVLKLIFNsiYLLVFNMGIYGAIYASLSAYILTSIWMYYDL 220
Cdd:cd13128 342 FGSILQAIGKQKLTLKILLIGALLNVILN--LLLIPKYGIIGAAIATLISEFIIFILLLYLL 401
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
142-232 |
7.40e-05 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 42.56 E-value: 7.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 142 YFSLYSLIIPFQFMAAIFNSIKSATGEPEATFYRMFVLLVLKLIFNsiYLLVFNMGIYGAIYASLSAYILTSIWMYYDLf 221
Cdd:pfam14667 1 VLQILALSIIFLSLSTVLTSILQGLGRTKLALIALLIGALVKLILN--LLLIPLFGIVGAAIATVISLLVVALLNLYYL- 77
|
90
....*....|.
gi 1055149658 222 IKKYKFKLNLR 232
Cdd:pfam14667 78 RRYLGLRLLLR 88
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
63-443 |
1.42e-04 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 44.00 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 63 SYVQPAINMIIALSQGFGVVALS-MIGQLNGKNDENGVRNVSLQILIFSFITGIILMPVALLSARFFVPdnpVLKQDALI 141
Cdd:cd13124 34 QMAYPIYGIFLTLATAGIPVAISkLVAEYNALGDYKGARRIFRVSLILLLILGLVFFLLLFFGAPFLAQ---LLLGDPRL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 142 YFSLYSLIIPFQFMAAI----------FNSIKSATGEPEATFYRMFVLLVLklifnSIYLLVFNMGI-YGAIYASLSAYI 210
Cdd:cd13124 111 APVIRALAPAILIVPLLsvlrgyfqglQNMTPTAVSQVIEQIVRVIVILVL-----AYLLLPVGGGLyYAAAGATFGAVI 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 211 --LTS-IWMYYDLFIKKYKFKLNLREYKFDIV----VIKELIKLAIPSMLTYMGINLGFFLINkeVVVYGSDVLAGLA-- 281
Cdd:cd13124 186 gaLAGlLVLLYYYRKKRRELKRLLRKSPRSKIstkeILKELLSYAIPITLSSLILPLLQLIDS--FTVPRRLQAAGLSes 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 282 -----------IATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNKGVLIGNIVALILVVLVLPTSKYIVALF 350
Cdd:cd13124 264 eatalygiltgRAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRLTLLIGLPAAVGLAVLAEPINTLL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 351 KPTDQIANIaiesLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLIMSFLRIwFLRYFFILLTSSFLGYYSVFYGNLVSNF 430
Cdd:cd13124 344 FGDSEGGLI----LQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGL-LVKIVLNYVLIPIFGIYGAAIATVIGFL 418
|
410
....*....|...
gi 1055149658 431 IAGLIFYIMVKKS 443
Cdd:cd13124 419 VAALLNLRALKKL 431
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
12-218 |
1.52e-04 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 43.85 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 12 RREMILNGNIISTMIFLTIPTFMMAIVQTLIPFSDSLFLNIKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLN 91
Cdd:cd12082 208 LSLLKPDLELLRRLLRIGLPSAIQNSLLSLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNL 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 92 GKNDENGVRNVSLQILIFSFITGIILMPVALLSARFFV---PDNPVLKQDALIYFSLYSLIIPFQFMAAIFNSIKSATGE 168
Cdd:cd12082 288 GAGNFDRARRITWVALLIGLLIGAVLGLLILLFPEPILslfTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGR 367
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1055149658 169 PEATFYRMFVLLVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYY 218
Cdd:cd12082 368 TLKSLIVSLLSYWVVRLPLAYVLAYLGLGLYGIWLALVISLILAALVLLL 417
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
240-395 |
3.55e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 42.60 E-value: 3.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 240 VIKELIKLAIPSMLTYMGINLGFFLINKEVVVYGSDVLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKK 319
Cdd:cd13144 6 VLRLLLTMSIPAMISMLFQALYNIVDSIFVARLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANK 85
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1055149658 320 IFNKGVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRTIYPLI 395
Cdd:cd13144 86 AANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMI 161
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
29-321 |
4.31e-04 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 42.67 E-value: 4.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 29 TIPTFMMAIVQTLIPFSDSLFLNIKLGNNVAAAVSYVQPAINMIIALSQGFGVVALSMIGQLNGKNDENGVRnvslQILI 108
Cdd:PRK09575 18 TIPSIAAMLVNGLYQIVDGIFIGHYVGAEGLAGINMAWPVIGIILGIGLMVGMGTGSLLSIKRGEGDLEKAK----RILT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 109 FSFITGIILMPVALLSARFFVpDNPVLKQDALIYFSLYSL--IIPFQFmAAIFNSIKSAT-------GEPEATFYRMFVL 179
Cdd:PRK09575 94 TGLLLLLLLGPIVSVILFLFA-DDFLRAQGAEGRTLELALqyIQVLIW-GCLFTLGAIALpfllrndESPNLATGLMVIG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 180 LVLKLIFNSIYLLVFNMGIYGAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREYKFDIVVIKELIKLAIPSMLTYMGIN 259
Cdd:PRK09575 172 ALINIVLDYLFIGWLDWGLTGAAIATALAQLVVTVLGLGYFFSSRANIRLTLKELRFNWSLAPKIVLLGSSSFFMYLYGS 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1055149658 260 LGFFLINKEVVVYGSDVLAG-LAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIF 321
Cdd:PRK09575 252 FVVALHNRLFMEYGSALTVGaYAIVGYLMVLYYLVAEGIAEGMQPPVSYYFGARQYDNIKKLL 314
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
24-445 |
1.43e-03 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 40.63 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 24 TMIFLTIPTFMMAIVQTLIPFSDSLFLNiKLGNNVAAAVSyVQPAINMIIALSQGFGVVAL--SMIGQLNG-KNDEngVR 100
Cdd:cd13132 4 KLLRLAAPLVLTSLLQYSLSVVSVVFVG-HLGKLELAAAS-LASSFANVTGFSILLGLASAldTLCGQAFGaKNYK--LV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 101 NVSLQ-ILIFSFITGIILMPVALLSARFFVpdnpVLKQDALI------YFSLYSLIIPFQFMAAIFNSIKSATGEPEATF 173
Cdd:cd13132 80 GVYLQrALVILLLCCVPISLLWLNTEPILL----LLGQDPEIarlageYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 174 YRMFVLLVLKLIFNsiYLLVFNMGIY---GAIYASLSAYILTSIWMYYDLFIKKYKFKLNLREyKFDIVVIKELIKLAIP 250
Cdd:cd13132 156 YISLVALLLNILLN--YLLVFVLGLGfigAALATSISYWLIVVLLLLYIFFSKGHKATWGGFS-REAFRGWGPFLKLAIP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 251 SML-------TYMGINLGFFLINKEVVvygsdvLAGLAIATQVTNICFTMPTCVATTVTTMISINIGVENVEKSKKIFNK 323
Cdd:cd13132 233 SALmlclewwAFEILVLLAGLLPGTVA------LAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRAKLAAIV 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1055149658 324 GVLIGNIVALILVVLVLPTSKYIVALFKPTDQIANIAIESLKIYIYSVFPYSVFMMSQAVYNALGRtiyPLIMSFLRIWF 403
Cdd:cd13132 307 ALILSLVIGVVVAILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCGR---QKLGAYVNLVA 383
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1055149658 404 LrYFFILLTSSFLGYYSVF------YGNLVSNFIAGLIFYIMVKKSSW 445
Cdd:cd13132 384 Y-YLIGLPVGLLLAFVLGLglkglwIGLIAGLILQAVILLLIILRTDW 430
|
|
| |
