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Conserved domains on  [gi|1056582256|ref|WP_068013657|]
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ABC transporter permease [Rhodoplanes sp. Z2-YC6860]

Protein Classification

ABC transporter permease( domain architecture ID 11427288)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0022857|GO:0005524
PubMed:  35642569

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
12-261 1.96e-45

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 152.99  E-value: 1.96e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  12 APVRGWSARNVAAHLFTVACLAIWEGASL--VAPSYLLPGPVPVVQRLWVFVTSARDLGHLGASLFHVATAIAISFVIGT 89
Cdd:COG0600     3 TSTRRRLRRLLLPLLSLALLLALWELAARlgLVPPFLLPSPSAVLAALVELLASGELWEHLLASLLRVLLGFALAALLGV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  90 LLALIPYYVPVLRFAIERRIGpFLNAFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGS 169
Cdd:COG0600    83 PLGLLLGLSRLLRRLLDPLLV-FLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARS 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 170 FTRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVLIIAFVHGMDr 249
Cdd:COG0600   162 LGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLD- 240
                         250
                  ....*....|..
gi 1056582256 250 YVLGPLQQSVSR 261
Cdd:COG0600   241 LLLRLLERRLLR 252
 
Name Accession Description Interval E-value
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
12-261 1.96e-45

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 152.99  E-value: 1.96e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  12 APVRGWSARNVAAHLFTVACLAIWEGASL--VAPSYLLPGPVPVVQRLWVFVTSARDLGHLGASLFHVATAIAISFVIGT 89
Cdd:COG0600     3 TSTRRRLRRLLLPLLSLALLLALWELAARlgLVPPFLLPSPSAVLAALVELLASGELWEHLLASLLRVLLGFALAALLGV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  90 LLALIPYYVPVLRFAIERRIGpFLNAFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGS 169
Cdd:COG0600    83 PLGLLLGLSRLLRRLLDPLLV-FLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARS 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 170 FTRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVLIIAFVHGMDr 249
Cdd:COG0600   162 LGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLD- 240
                         250
                  ....*....|..
gi 1056582256 250 YVLGPLQQSVSR 261
Cdd:COG0600   241 LLLRLLERRLLR 252
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
13-239 1.59e-17

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 79.59  E-value: 1.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  13 PVRGWSARnVAAHLFTVACLAIWEGASLVA--PSYLLPGPVPVVQRLWVFVTSARDLGHLGASLFHVATAIAISFVIGTL 90
Cdd:PRK11365    4 PVKKWLLR-VAPWFLPVGIVAVWQLASSVGwlSTRILPSPEGVVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  91 LALIPYYVPVLRFAIERRIgPFLNAFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGSF 170
Cdd:PRK11365   83 LGLISGLSRWGERLLDTSI-QMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSY 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1056582256 171 TRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVL 239
Cdd:PRK11365  162 GLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIIL 230
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
115-244 4.06e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.92  E-value: 4.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 115 AFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGSFTRKRSRMFALVIVPSLYPFIFATL 194
Cdd:pfam00528  34 VLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGL 113
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1056582256 195 RIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVLIIAFV 244
Cdd:pfam00528 114 ALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALIL 163
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
70-244 1.66e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 44.58  E-value: 1.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  70 LGASLFHVATAIAISFVIGTLLALIPYYVPVLRFAIERRIGPFLNAFSAIGWTLLSIMWFGVTP---------FTVIFAI 140
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgilpglgLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 141 SAVLVPFALVNMTAGLNNIDAEMIEMAGSFTRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYM 220
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                         170       180
                  ....*....|....*....|....
gi 1056582256 221 INLARQEFDTTTIFAAIVLIIAFV 244
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALI 184
 
Name Accession Description Interval E-value
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
12-261 1.96e-45

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 152.99  E-value: 1.96e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  12 APVRGWSARNVAAHLFTVACLAIWEGASL--VAPSYLLPGPVPVVQRLWVFVTSARDLGHLGASLFHVATAIAISFVIGT 89
Cdd:COG0600     3 TSTRRRLRRLLLPLLSLALLLALWELAARlgLVPPFLLPSPSAVLAALVELLASGELWEHLLASLLRVLLGFALAALLGV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  90 LLALIPYYVPVLRFAIERRIGpFLNAFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGS 169
Cdd:COG0600    83 PLGLLLGLSRLLRRLLDPLLV-FLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARS 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 170 FTRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVLIIAFVHGMDr 249
Cdd:COG0600   162 LGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLD- 240
                         250
                  ....*....|..
gi 1056582256 250 YVLGPLQQSVSR 261
Cdd:COG0600   241 LLLRLLERRLLR 252
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
13-239 1.59e-17

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 79.59  E-value: 1.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  13 PVRGWSARnVAAHLFTVACLAIWEGASLVA--PSYLLPGPVPVVQRLWVFVTSARDLGHLGASLFHVATAIAISFVIGTL 90
Cdd:PRK11365    4 PVKKWLLR-VAPWFLPVGIVAVWQLASSVGwlSTRILPSPEGVVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  91 LALIPYYVPVLRFAIERRIgPFLNAFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGSF 170
Cdd:PRK11365   83 LGLISGLSRWGERLLDTSI-QMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSY 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1056582256 171 TRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVL 239
Cdd:PRK11365  162 GLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIIL 230
PRK10160 PRK10160
taurine ABC transporter permease TauC;
7-243 4.52e-13

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 67.50  E-value: 4.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256   7 ALAREAPVRGWSA-RNVAAHLFTVAC-LAIWEGAS---LVAPSYLlPGPVPVVQRLWVFVTS-----ARDLGHLGASLFH 76
Cdd:PRK10160    8 KLHSRRLKWRWPLsRQLTLSIGTLAVlLAVWWAVAalqLISPLFL-PPPQQVLAKLLTIAGPqgfmdATLWQHLAASLTR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  77 VATAIAISFVIGTLLALIPYYVPVLRFAIERRIgPFLNAFSAIGWTLLSIMWFGVTPFTVIFAIsaVLVPFALVNMT--A 154
Cdd:PRK10160   87 IVLALLAAVVIGIPVGIAMGLSPTVRGILDPLI-ELYRPVPPLAYLPLMVIWFGIGETSKILLI--YLAIFAPVAMSalA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 155 GLNNIDAEMIEMAGSFTRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIF 234
Cdd:PRK10160  164 GVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVL 243
                         250
                  ....*....|.
gi 1056582256 235 AAIVLI--IAF 243
Cdd:PRK10160  244 AGIAVIaiIAF 254
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
115-244 4.06e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.92  E-value: 4.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 115 AFSAIGWTLLSIMWFGVTPFTVIFAISAVLVPFALVNMTAGLNNIDAEMIEMAGSFTRKRSRMFALVIVPSLYPFIFATL 194
Cdd:pfam00528  34 VLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGL 113
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1056582256 195 RIMFGVAWKVTLTAELFGGNSGLGYMINLARQEFDTTTIFAAIVLIIAFV 244
Cdd:pfam00528 114 ALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALIL 163
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
70-244 1.66e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 44.58  E-value: 1.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256  70 LGASLFHVATAIAISFVIGTLLALIPYYVPVLRFAIERRIGPFLNAFSAIGWTLLSIMWFGVTP---------FTVIFAI 140
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgilpglgLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1056582256 141 SAVLVPFALVNMTAGLNNIDAEMIEMAGSFTRKRSRMFALVIVPSLYPFIFATLRIMFGVAWKVTLTAELFGGNSGLGYM 220
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                         170       180
                  ....*....|....*....|....
gi 1056582256 221 INLARQEFDTTTIFAAIVLIIAFV 244
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALI 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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