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Conserved domains on  [gi|1060750945|ref|WP_069139728|]
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MULTISPECIES: NAD kinase [Stenotrophomonas]

Protein Classification

NAD kinase( domain architecture ID 10012223)

ATP-dependent NAD kinase catalyzes the phosphorylation of NAD to NADP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 11-256 9.01e-159

inorganic polyphosphate/ATP-NAD kinase; Reviewed


:

Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 440.41  E-value: 9.01e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  11 ASSTEPAQMARAAMISRYGDHAPEQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRgDDDVQARIARA 90
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYS-EDDLLERIAAA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  91 EPANLRPLEMVALTESGTSTGSLAYNDVSLLRQTRQAAHIGIDLNGQERVAELIGDGVLVATPAGSTAYNYSAHGPVLPL 170
Cdd:PRK04761   80 EPTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 171 GSHTIALTPLAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETRDVVEVTIRESRDRRVTLLFDPEHNLEDRI 250
Cdd:PRK04761  160 GSNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERI 239


                  ....*.
gi 1060750945 251 LSEQFV 256
Cdd:PRK04761  240 LAEQFG 245
 
Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 11-256 9.01e-159

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 440.41  E-value: 9.01e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  11 ASSTEPAQMARAAMISRYGDHAPEQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRgDDDVQARIARA 90
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYS-EDDLLERIAAA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  91 EPANLRPLEMVALTESGTSTGSLAYNDVSLLRQTRQAAHIGIDLNGQERVAELIGDGVLVATPAGSTAYNYSAHGPVLPL 170
Cdd:PRK04761   80 EPTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 171 GSHTIALTPLAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETRDVVEVTIRESRDRRVTLLFDPEHNLEDRI 250
Cdd:PRK04761  160 GSNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERI 239


                  ....*.
gi 1060750945 251 LSEQFV 256
Cdd:PRK04761  240 LAEQFG 245
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
30-255 1.06e-70

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 218.47  E-value: 1.06e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  30 DHAPEQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRGD-DDVQARIARAEPANLRPLEM-VALTESG 107
Cdd:COG0061    47 EELGEEADLVIVLGGDGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEElEEALERLLAGEYEVEERLLLeATVDRDG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 108 TSTGS-LAYNDVSLLRQTR-QAAHIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPYRP 185
Cdd:COG0061   127 EVVHEaLALNEVVVLRGSIaRMIELEVYIDG-EFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTL 205

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1060750945 186 rRWRGAILKADTEVRFRVLDPYkRPVSVTADSHETRDV---VEVTIRESrDRRVTLLFDPEHNLEDRiLSEQF 255
Cdd:COG0061   206 -SSRPLVLPDDSEIEIEVLEDS-RPAVLVADGQEVRDLepgDRVEIRRS-PKPVRLLRLKDHSFFER-LREKL 274
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 140-227 1.25e-05

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 43.44  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 140 VAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPYrPRRWRGAILKADTEVRFRVLDPyKRPVSVTADSHE 219
Cdd:pfam20143  26 LGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPH-SLSSRPIVVSSSSKLRIRVLSR-AEALLVDDGDPE 103

                          90
                  ....*....|..
gi 1060750945 220 T----RDVVEVT 227
Cdd:pfam20143 104 LdispGDRVRVR 115
 
Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 11-256 9.01e-159

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 440.41  E-value: 9.01e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  11 ASSTEPAQMARAAMISRYGDHAPEQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRgDDDVQARIARA 90
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYS-EDDLLERIAAA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  91 EPANLRPLEMVALTESGTSTGSLAYNDVSLLRQTRQAAHIGIDLNGQERVAELIGDGVLVATPAGSTAYNYSAHGPVLPL 170
Cdd:PRK04761   80 EPTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 171 GSHTIALTPLAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETRDVVEVTIRESRDRRVTLLFDPEHNLEDRI 250
Cdd:PRK04761  160 GSNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERI 239


                  ....*.
gi 1060750945 251 LSEQFV 256
Cdd:PRK04761  240 LAEQFG 245
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
30-255 1.06e-70

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 218.47  E-value: 1.06e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  30 DHAPEQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRGD-DDVQARIARAEPANLRPLEM-VALTESG 107
Cdd:COG0061    47 EELGEEADLVIVLGGDGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEElEEALERLLAGEYEVEERLLLeATVDRDG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 108 TSTGS-LAYNDVSLLRQTR-QAAHIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPYRP 185
Cdd:COG0061   127 EVVHEaLALNEVVVLRGSIaRMIELEVYIDG-EFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTL 205

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1060750945 186 rRWRGAILKADTEVRFRVLDPYkRPVSVTADSHETRDV---VEVTIRESrDRRVTLLFDPEHNLEDRiLSEQF 255
Cdd:COG0061   206 -SSRPLVLPDDSEIEIEVLEDS-RPAVLVADGQEVRDLepgDRVEIRRS-PKPVRLLRLKDHSFFER-LREKL 274
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 33-203 4.87e-21

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 89.60  E-value: 4.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  33 PEQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFL--MNQYRGDDDVQARIARAEPANLRPLemVALTESGTST 110
Cdd:PRK01911   62 DGSADMVISIGGDGTFLRTATYVGNSNIPILGINTGRLGFLatVSKEEIEETIDELLNGDYTIEERSL--LQLESNPKLF 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 111 GSLAY--NDVSLLRqTRQAAHIGID--LNGqERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPY--- 183
Cdd:PRK01911  140 GELNFalNEIAILK-RDTSSMITVHtyLNG-EYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHnln 217

                         170       180
                  ....*....|....*....|.
gi 1060750945 184 -RPrrwrgAILKADTEVRFRV 203
Cdd:PRK01911  218 vRP-----LVIPDDTEITLEV 233
pnk PRK14077
NAD(+) kinase;
37-239 9.18e-20

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 85.99  E-value: 9.18e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  37 DVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFL----MNQ--------YRGDDDVQariaraepanlRP--LEMVA 102
Cdd:PRK14077   66 DFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLtditVDEaekffqafFQGEFEIE-----------KPymLSVFL 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 103 LTESGTSTGSLAYNDVSLLRQTRQA-AHIGIDLNGQeRVAELIGDGVLVATPAGSTAYNYSAHGPVL-PLgSHTIALTPL 180
Cdd:PRK14077  135 EKKQGKILEKLAFNDVVISKNNQASmAHIEAFLNEK-YFNEYFGDGVIVATPAGSTAYNMSANGPIIyPL-SQVFILTPV 212

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1060750945 181 APYRPRRwRGAILKADTEVRFRVldpyKRPVSVTADSHETRDVVEVTIRESR--DRRVTLL 239
Cdd:PRK14077  213 CSHSLTQ-RPIVLPKGFEVEFKT----KSDCILCIDGQDRYKMNDFKSIKVGlsDKNVALI 268
ppnK PRK01185
NAD(+) kinase;
36-251 3.77e-16

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 75.62  E-value: 3.77e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  36 ADVLCPLGGDGFMLQTLHR-HGhlgkPVFGMKLGTVGFLMNQyrGDDDVQARIARAEPANLRPLEMVAL--------TES 106
Cdd:PRK01185   53 ADVIITIGGDGTILRTLQRaKG----PILGINMGGLGFLTEI--EIDEVGSAIKKLIRGEYFIDERMKLkvyingerLED 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 107 GTSTGSLAYNDVSLLRQTRqaahigIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPYRpR 186
Cdd:PRK01185  127 CTNEAVIHTDRIAKIRQFK------IYYDG-HFLDTFKADGVIVATPTGSTSYSSSAGGPILLPNLEGMVISYIAPYS-S 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1060750945 187 RWRGAILKADTEVRFRVLDPyKRPVSVTADSHETR----DVVEVTIRESRDRRVTLLFDPEHNLEDRIL 251
Cdd:PRK01185  199 RPKSVVVPSESTVEIKIAGD-QSSLLILDGQYEYKiskgDTVEISKSENYARFISFRESPYDRIREKLI 266
ppnK PRK02155
NAD kinase;
17-245 7.52e-16

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 75.36  E-value: 7.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  17 AQMARAAMISRYGDHAPE----QADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMnqyrgD---DDVQARIAR 89
Cdd:PRK02155   41 ADTARNIGLTGYPALTPEeigaRADLAVVLGGDGTMLGIGRQLAPYGVPLIGINHGRLGFIT-----DiplDDMQETLPP 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  90 AEPAN----LRPLEMVALTESGTST-GSLAYNDVSLLR-QTRQAAHIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSA 163
Cdd:PRK02155  116 MLAGNyeeeERMLLEARVVRDGEPIfHALAFNDVVVNRsGFSGMVELRVSVDG-RFMYNQRSDGLIVATPTGSTAYALSA 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 164 HGPVLPLGSHTIALTPLAPY----RPrrwrgAILKADTEVRFRVLdpYKRPVSVTADSHETRDVVE---VTIRESrDRRV 236
Cdd:PRK02155  195 GGPILHPQLPGWVLVPIAPHtlsnRP-----IVLPDDSEVAIQIV--GGRDVSVNFDMQSLTSLELgdrIEVRRS-PHTV 266


                  ....*....
gi 1060750945 237 TLLFDPEHN 245
Cdd:PRK02155  267 RFLHPVGYS 275
pnk PRK14075
NAD(+) kinase;
36-245 1.92e-15

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 73.61  E-value: 1.92e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  36 ADVLCPLGGDGFMLQTLHRhghLGKPVFGMKLGTVGFLMNQYRGDDDVQARIARAEpaNLRPLEMVALTESGTSTGSLAY 115
Cdd:PRK14075   42 ADLIIVVGGDGTVLKAAKK---VGTPLVGFKAGRLGFLSSYTLEEIDRFLEDLKNW--NFREEKRWFLKIESELGNHLAL 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 116 NDVSLLRQTRQAAhIGIDLNGQERVAELI-GDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPYRPRRwRGAILK 194
Cdd:PRK14075  117 NDVTLERDPSQKM-VEIEVSFEDHSSMWFfADGVVISTPTGSTAYSLSLGGPIILPNCEVFEITPIAPQFLAT-RSIVIP 194

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1060750945 195 ADTEVRFRVLdpykRPVSVTADSHETRDVVEVTIRESRdRRVTLLFDPEHN 245
Cdd:PRK14075  195 SNEKVTVESQ----RDINLIVDGVLVGKTNRITVKKSR-RYVRILRPKDYD 240
ppnK PRK03708
NAD(+) kinase;
36-231 1.33e-12

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 65.89  E-value: 1.33e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  36 ADVLCPLGGDGFMLQTLHRHGHlGKPVFGMKLGTVGFLmnqyrgdddvqariARAEPANL-----RPLEMVALTESGTST 110
Cdd:PRK03708   58 VDFIIAIGGDGTILRIEHKTKK-DIPILGINMGTLGFL--------------TEVEPEETffalsRLLEGDYFIDERIKL 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 111 GSL--------AYNDVSLLrqTRQAA---HIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTP 179
Cdd:PRK03708  123 RVYingenvpdALNEVVIL--TGIPGkiiHLKYYVDG-ELADEVRADGLIISTPTGSTAYAMSAGGPFVDPRLDAILIAP 199

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1060750945 180 LAPYrPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETR--DVVEVTIRES 231
Cdd:PRK03708  200 LCPF-KLSSRPMVVPSSSRIDVKLLRTGREIILVIDGQYYEElpPDTEITIKKS 252
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 36-182 1.74e-11

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 62.95  E-value: 1.74e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  36 ADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRGD--DDVQARIARAEPANLRPLEMVALTESGTSTGS- 112
Cdd:PRK04539   69 CDLVAVLGGDGTFLSVAREIAPRAVPIIGINQGHLGFLTQIPREYmtDKLLPVLEGKYLAEERILIEAALIREGKTAERa 148

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1060750945 113 LAYNDVSLlrqTRQAAHIGIDLN---GQERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAP 182
Cdd:PRK04539  149 LALNDAVL---SRGGAGQMIEFEvfvNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICP 218
ppnK PRK01231
NAD(+) kinase;
34-245 6.25e-11

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 61.13  E-value: 6.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  34 EQADVLCPLGGDGFML---QTLHRHGhlgKPVFGMKLGTVGFLMnqyrgD---DDVQARIA-------RAEPANLrpLEM 100
Cdd:PRK01231   61 EVCDLVIVVGGDGSLLgaaRALARHN---VPVLGINRGRLGFLT-----DirpDELEFKLAevldghyQEEERFL--LEA 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 101 VALTESGTSTGSLAYNDVSLLRQtrQAAH-IGIDLN-GQERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALT 178
Cdd:PRK01231  131 EVRRGGEVIGQGDALNDVVLHPG--KSTRmIEFELYiDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIVLV 208

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1060750945 179 PLAPY----RPrrwrgAILKADTEVRFRVLDPYKRPVSVTADSHETRDVV---EVTIRESRDrRVTLLFDPEHN 245
Cdd:PRK01231  209 PMFPHtlssRP-----IVVDGNSEIKIVISKDNRTYPRVSCDGQNSVTLApgdTVTIRKKPQ-KLRLIHPLDYN 276
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 29-168 1.65e-09

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 57.23  E-value: 1.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  29 GDHAPEQADVLCPLGGDGFMLQT--LHRHGHLgkPVFGMKLGTVGFLMNQYRGD-DDVQARIARAEPANLRPLEM-VALT 104
Cdd:PRK03372   66 DPDAADGCELVLVLGGDGTILRAaeLARAADV--PVLGVNLGHVGFLAEAEAEDlDEAVERVVDRDYRVEERMTLdVTVR 143

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1060750945 105 ESGTSTG-SLAYNDVSLLRQTRQA---AHIGIDlngqER-VAELIGDGVLVATPAGSTAYNYSAHGPVL 168
Cdd:PRK03372  144 VGGEIVWrGWALNEASLEKADREGmleVVLEVD----GRpVSSFGCDGVLVSTPTGSTAYAFSAGGPVV 208
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
42-205 6.91e-09

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 55.89  E-value: 6.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  42 LGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYR------------GDDDVQARiaraepanlRPLEMVALTESGTS 109
Cdd:PRK14076  355 IGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKeeifkaidsiisGEYEIEKR---------TKLSGFILKDGHQN 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 110 TGSLAYNDVSLLrqTRQAA---HIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPY--- 183
Cdd:PRK14076  426 ILPSALNEVVIT--TKNPAkmlHFEVYVNG-ELVEEVRADGIIISTPTGSTAYSLSAGGPIVEPTVDGFIIVPICPFkls 502

                         170       180
                  ....*....|....*....|...
gi 1060750945 184 -RPrrwrgAILKADTEVRFRVLD 205
Cdd:PRK14076  503 sRP-----LVVSANSEIKIKLLK 520
ppnK PRK02231
NAD(+) kinase;
34-185 8.30e-09

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 54.81  E-value: 8.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  34 EQADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLM-----NQY--------RGDDDVQARIAraepanlrpLEM 100
Cdd:PRK02231   41 QRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFLTdidpkNAYeqleacleRGEFFVEERFL---------LEA 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 101 VALTESGTSTGSLAYNDVSLlrQTRQAAHIgID----LNGQERVAELiGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIA 176
Cdd:PRK02231  112 KIERNGKIIATSNALNEVVI--HPAKIAHM-IDfhvyIDDKFAFSQR-SDGLIISTPTGSTAYSLSAGGPILTPNLNAIA 187

                         170
                  ....*....|...
gi 1060750945 177 LTPLAPY----RP 185
Cdd:PRK02231  188 LVPMFPHtlssRP 200
ppnK PRK00561
NAD(+) kinase;
36-208 1.10e-08

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 54.50  E-value: 1.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  36 ADVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFlMNQYRGDDDVQARIARAEPANLRPLEMVALTESGTStgSLAY 115
Cdd:PRK00561   34 ADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGF-YTSFNETDLDQNFANKLDQLKFTQIDLLEVQIDDQI--HLVL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 116 NDVSLLRQTRQAAHIGIDLNGQERVAeliGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAP-YRPRR---WRGA 191
Cdd:PRK00561  111 NELAVYTNTAYPINIFIDNEFWEKYR---GSGLLIGPRTGSTALAKSAKGAVIFPRIDVIQIIELNPlLHPNQttiQSPI 187

                         170
                  ....*....|....*..
gi 1060750945 192 ILKADTEVRFRVLDPYK 208
Cdd:PRK00561  188 ILPIDTKVEFEIKKAFD 204
ppnK PRK02645
NAD(+) kinase;
32-182 1.65e-08

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 54.15  E-value: 1.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  32 APEQADVLCPLGGDGFMLqTLHRH-GHLGKPVFGMKLG-TVGFLMNQYR--GDDDV-----------------QARIARA 90
Cdd:PRK02645   54 ASELIDLAIVLGGDGTVL-AAARHlAPHDIPILSVNVGgHLGFLTHPRDllQDESVwdrlqedryaierrmmlQARVFEG 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  91 EPANLRPLEmvaltESgtstgSLAYNDV---SLLRQTRQAAHIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPV 167
Cdd:PRK02645  133 DRSNEEPVS-----ES-----YYALNDFylkPASEDRSPTCILELEIDG-EVVDQYQGDGLIVSTPTGSTAYTMAAGGPI 201

                         170
                  ....*....|....*
gi 1060750945 168 LPLGSHTIALTPLAP 182
Cdd:PRK02645  202 LHPGIDAIIVTPICP 216
ppnK PRK02649
NAD(+) kinase;
42-183 1.41e-07

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 51.52  E-value: 1.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  42 LGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLMNQYRGDDD--VQARIARAEPANLRP-LEMVALTESGTSTGSLAYNDV 118
Cdd:PRK02649   75 LGGDGTVLSAARQLAPCGIPLLTINTGHLGFLTEAYLNQLDeaIDQVLAGQYTIEERTmLTVSVMRGDQLRWEALSLNEM 154

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1060750945 119 SLLRQTRQA-AHIGIDLnGQERVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPY 183
Cdd:PRK02649  155 VLHREPLTSmCHFEIAI-GRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPDVPVLQLTPICPH 219
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 6-168 3.02e-07

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 50.20  E-value: 3.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945   6 RIAFLASSTEPAQMARAAMISRYGD----HAPEQADVLCPLGGDGFMLQTLHRHGH-LGKPVF-GMKLGTVGFLMNqYRg 79
Cdd:PRK04885    2 KVAIISNGDPKSKRVASKLKKYLKDfgfiLDEKNPDIVISVGGDGTLLSAFHRYENqLDKVRFvGVHTGHLGFYTD-WR- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  80 DDDVQARIAraepaNLR---------P-LEMVALTESGTSTGSLAYNDVSLLRQTRQ-AAHIGIdlNGQ--ERVAeliGD 146
Cdd:PRK04885   80 PFEVDKLVI-----ALAkdpgqvvsyPlLEVKITYEDGEKEKYLALNEATIKRIEGTlVADVYI--NGVlfERFR---GD 149

                         170       180
                  ....*....|....*....|..
gi 1060750945 147 GVLVATPAGSTAYNYSAHGPVL 168
Cdd:PRK04885  150 GLCVSTPTGSTAYNKSLGGAVL 171
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 146-234 1.03e-06

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 48.78  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 146 DGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPY----RPrrwrgAILKADTEVRFRVlDPYKRPVSVTADSHETR 221
Cdd:PRK03378  177 DGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHtlsaRP-----LVIDSSSTIRLKF-SPNRSDLEISCDSQIAL 250

                          90
                  ....*....|....*.
gi 1060750945 222 DVV---EVTIRESRDR 234
Cdd:PRK03378  251 PIQpgeEVLIRRSDYH 266
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 140-227 1.25e-05

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 43.44  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 140 VAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAPYrPRRWRGAILKADTEVRFRVLDPyKRPVSVTADSHE 219
Cdd:pfam20143  26 LGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPH-SLSSRPIVVSSSSKLRIRVLSR-AEALLVDDGDPE 103

                          90
                  ....*....|..
gi 1060750945 220 T----RDVVEVT 227
Cdd:pfam20143 104 LdispGDRVRVR 115
ppnK PRK03501
NAD kinase;
145-205 2.57e-05

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 44.20  E-value: 2.57e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1060750945 145 GDGVLVATPAGSTAYNYSAHGPVL-PLgSHTIALTPLAPYRPRRWR--GA--ILKADTEVRFRVLD 205
Cdd:PRK03501  149 GDGMVVSTPTGSTAYNKSVRGAVVdPL-IPCFQVSELASLNNNTYRtlGSpfILSHERKLTLKIVQ 213
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 37-185 8.70e-05

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 43.28  E-value: 8.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945  37 DVLCPLGGDGFMLQTLHRHGHLGKPVFGMKLGTVGFLM----NQYRgdDDVQARIARAEPANLRP------LEMVALTES 106
Cdd:PLN02935  264 DLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTpfhsEQYR--DCLDAILKGPISITLRHrlqchiIRDAAKNEY 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1060750945 107 GTSTGSLAYNDVSLLRqtrqaahiGID--LNGQE------RVAELIGDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALT 178
Cdd:PLN02935  342 ETEEPILVLNEVTIDR--------GISsfLTNLEcycdnsFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFT 413

                         170
                  ....*....|.
gi 1060750945 179 PLAP----YRP 185
Cdd:PLN02935  414 PICPhslsFRP 424
PLN02727 PLN02727
NAD kinase
 145-185 2.21e-04

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 42.18  E-value: 2.21e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1060750945 145 GDGVLVATPAGSTAYNYSAHGPVLPLGSHTIALTPLAP----YRP 185
Cdd:PLN02727  863 GDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPhslsFRP 907
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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