|
Name |
Accession |
Description |
Interval |
E-value |
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
241-719 |
3.11e-97 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 309.98 E-value: 3.11e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 241 FAIHAEVEKGHTYTtQARLrpLLTKLLGDGELAAQAFKAGYHQAQYVLNheaGTYHPTAQLLMETVVAKRLLKLAKQQnr 320
Cdd:COG0507 33 ALLSRAAGEGHTFP-LEDL--AAARLLGVAEDIEAALAALVESGPLVLD---GRRYLTRLLEAEQRLARRLRRLARPA-- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 321 YDESTNAAFLAAV-NELPYELTAMQNEAVLTAL-DNAVSCITGGAGTGKTTVLRTALRAYGKMGFEVHAVALSGRAAMRL 398
Cdd:COG0507 105 LDEADVEAALAALePRAGITLSDEQREAVALALtTRRVSVLTGGAGTGKTTTLRALLAALEALGLRVALAAPTGKAAKRL 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 399 HESIGFKTMTIAALL---------RHEPIEPSDgsPNHLLVIDEASMIDLPTMYRLTNHL-HPAVRIIFTGDPNQLPPIG 468
Cdd:COG0507 185 SESTGIEARTIHRLLglrpdsgrfRHNRDNPLT--PADLLVVDEASMVDTRLMAALLEALpRAGARLILVGDPDQLPSVG 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 469 CGKVLADIVASQAIANVTLDIVKRQKGATGIPEYSMQVNQGLIPEHLSMG--NVYFHETS-KERIAQVCAELYQQSP--- 542
Cdd:COG0507 263 AGAVLRDLIESGTVPVVELTEVYRQADDSRIIELAHAIREGDAPEALNARyaDVVFVEAEdAEEAAEAIVELYADRPagg 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 543 ENSRVVGATTAMVAEINNLIQEAVNPDGarmIFEMYGETYRRNDLRQGDVILFTQNNYEKGIQNGSLGTLTRavgAGDDY 622
Cdd:COG0507 343 EDIQVLAPTNAGVDALNQAIREALNPAG---ELERELAEDGELELYVGDRVMFTRNDYDLGVFNGDIGTVLS---IDEDE 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 623 G--VVELDTGESVYVTQSLLDCMRLGYCITLHKAQGSQFPRIIIAL--QKGRIVDRAWLYTAITRAEHEVHIVGSTAEFA 698
Cdd:COG0507 417 GrlTVRFDGREIVTYDPSELDQLELAYAITVHKSQGSTFDRVILVLpsEHSPLLSRELLYTALTRARELLTLVGDRDALA 496
|
490 500
....*....|....*....|.
gi 1071011108 699 AitkAPSNAHNRNSYLRDLLK 719
Cdd:COG0507 497 R---AVRRDTARATGLAERLR 514
|
|
| recD_rel |
TIGR01448 |
helicase, putative, RecD/TraA family; This model describes a family similar to RecD, the ... |
97-718 |
2.71e-57 |
|
helicase, putative, RecD/TraA family; This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273632 [Multi-domain] Cd Length: 720 Bit Score: 207.71 E-value: 2.71e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 97 PETGEQLIQFIAKEpDFKGIGLGKARALWQLLGEQFHTTLRTDtPE--------SRERLKGILSDVSINALF-NGYAKYK 167
Cdd:TIGR01448 74 PTSKEGIVAYLSSR-SIKGVGKKLAQRIVKTFGEAAFDVLDDD-PEkllevpgiSKANLEKFVSQWSQQGDErRLLAGLQ 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 168 NLShcnwmaecrIPSSIQQRLLKFHGEGSVEAIKDNPYLLVG--FGMEFEEVDTLSQtKFEVELKDPKRLSAALEFA-IH 244
Cdd:TIGR01448 152 GLG---------IGIKLAQRIYKFYQADTLDRVEKDPYLLAEdvKGIGFLTADQLAQ-ALGIALNDPRRITAGLVYSlQQ 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 245 AEVEKGHTYTTQARLRPLLTKLLGDGELAAQAFKAGYHQAQYVLNHEAgtyhptAQLLMETVVAKRLLKLAKQQNRYD-- 322
Cdd:TIGR01448 222 ACTEEGHTYLPRNRFIKQVVHLLNVQPQERLLVPEAVELERLYLDEEP------KLAAEDGRIYLPSLFRAEKQIASHir 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 323 ---ESTNA--------AFLAAVNELPYELTAMQNEAVLTALDNAVSCITGGAGTGKTTVLRTALRAYGKMG--FEVHAVA 389
Cdd:TIGR01448 296 rllATSPAigaindqeHIWEVEKKLRKGLSEEQKQALDTAIQHKVVILTGGPGTGKTTITRAIIELAEELGglLPVGLAA 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 390 LSGRAAMRLHESIGFKTMTIAALLRHEPIEPSDGS-----PNHLLVIDEASMIDLPTMYRLTNHLHPAVRIIFTGDPNQL 464
Cdd:TIGR01448 376 PTGRAAKRLGEVTGLTASTIHRLLGYGPDTFRHNHledpiDCDLLIVDESSMMDTWLALSLLAALPDHARLLLVGDTDQL 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 465 PPIGCGKVLADIVASQAIANVTLDIVKRQKGATGIPEYSMQVNQGLIPE-----HLSMGNVYFHETSKERIAQVcaELYQ 539
Cdd:TIGR01448 456 PSVGPGQVLKDLILSQAIPVTRLTKVYRQAAGSPIITLAHGILHGEAPAwgdfkFLNLTRSEPEGAARHIPLMV--EKIV 533
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 540 QSPENSRVVGA----------TTAMVAEINNLIQEAVNPDGA-RMIFEMYGETYRRndlrqGDVILFTQNNYEKGIQNGS 608
Cdd:TIGR01448 534 GMARVGGIPGAdiqvlapmykGPLGIDALNQHLQALLNPYQKgQGGIEIAEGEYRK-----GDRVMQTKNDYNNEIFNGD 608
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 609 LGTLTRAVGA---GDDYGVVELDTGESVYVTQSLLDcMRLGYCITLHKAQGSQFPRII--IALQKGRIVDRAWLYTAITR 683
Cdd:TIGR01448 609 LGMIVKIEGAkqgKKDQVVVDFDGNEVELTRAELFN-LTLAYATSIHKSQGSEFPTVIlpIHTAHMRMLYRNLLYTALTR 687
|
650 660 670
....*....|....*....|....*....|....*
gi 1071011108 684 AEHEVHIVGSTAEFAAITKapSNAHNRNSYLRDLL 718
Cdd:TIGR01448 688 AKKRVILVGSAEAFDIAAA--RQGQARNTGLLERI 720
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
344-490 |
3.31e-38 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 139.23 E-value: 3.31e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 344 QNEAVLTALDNAVSCITGGAGTGKTTVLRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAALLRHEPIEPSDG 423
Cdd:cd17933 2 QKAAVRLVLRNRVSVLTGGAGTGKTTTLKALLAALEAEGKRVVLAAPTGKAAKRLSESTGIEASTIHRLLGINPGGGGFY 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1071011108 424 ------SPNHLLVIDEASMIDLPTMYRLTNHLHPAVRIIFTGDPNQLPPIGCGKVLADIVASQAIANVTLDIV 490
Cdd:cd17933 82 yneenpLDADLLIVDEASMVDTRLMAALLSAIPAGARLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTEV 154
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
367-513 |
2.77e-27 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 109.19 E-value: 2.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 367 KTTVLRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAALLrHEPIEPSDGSPNHLLVIDEASMIDLPTMYRLT 446
Cdd:pfam13604 31 KTTALKALREAWEAAGYRVIGLAPTGRAAKVLGEELGIPADTIAKLL-HRLGGRAGLDPGTLLIVDEAGMVGTRQMARLL 109
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071011108 447 NHLHPA-VRIIFTGDPNQLPPIGCGKVLADIVASQAIAnVTLDIVKRQKgATGIPEYSMQVNQGLIPE 513
Cdd:pfam13604 110 KLAEDAgARVILVGDPRQLPSVEAGGAFRDLLAAGIGT-AELTEIVRQR-DPWQRAASLALRDGDPAE 175
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
371-683 |
1.42e-16 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 84.36 E-value: 1.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 371 LRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAALLR-----HEPIEPSDgspnhLLVIDEASMIDLPTMYRL 445
Cdd:PRK13889 379 LGVAREAWEAAGYEVRGAALSGIAAENLEGGSGIASRTIASLEHgwgqgRDLLTSRD-----VLVIDEAGMVGTRQLERV 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 446 TNHLHPA-VRIIFTGDPNQLPPIGCG---KVLADIVASQAIANVTLDIVKRQKGATgipeysMQVNQGLIPEHL----SM 517
Cdd:PRK13889 454 LSHAADAgAKVVLVGDPQQLQAIEAGaafRSIHERHGGAEIGEVRRQREDWQRDAT------RDLATGRTGEALdayeAH 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 518 GNVYFHETSKERIAQVCAEL---YQQSPENSRVVGA-TTAMVAEINnliqeavnpDGARMIFEMYGE-------TYRRND 586
Cdd:PRK13889 528 GMVHAAATREQARADLIDRWdrdRQAAPDRSRIILThTNDEVRALN---------EAARERMRAAGDlgddvrvTVERGE 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 587 lRQ---GDVILFTQNNYEKGIQNGSLGTLtRAVGAgdDYGVVELDTGESVYVtqSLLDCMRL--GYCITLHKAQGSQFPR 661
Cdd:PRK13889 599 -RSfasGDRVMFLQNERGLGVKNGTLGTI-EQVSA--QSMSVRLDDGRSVAF--DLKDYDRIdhGYAATIHKAQGMTVDR 672
|
330 340
....*....|....*....|..
gi 1071011108 662 IIIALQKGriVDRAWLYTAITR 683
Cdd:PRK13889 673 THVLATPG--MDAHSSYVALSR 692
|
|
| HHH_4 |
pfam14490 |
Helix-hairpin-helix containing domain; This presumed domain contains at least one ... |
173-253 |
2.43e-13 |
|
Helix-hairpin-helix containing domain; This presumed domain contains at least one helix-hairpin-helix motif. This domain is often found in RecD helicases.
Pssm-ID: 464187 [Multi-domain] Cd Length: 91 Bit Score: 65.99 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 173 NWMAECRIPSSIQQRLLKFHGEGSVEAIKDNPYLLVG--FGMEFEEVDTLSQtKFEVELKDPKRLSAALEFAIHAEVEKG 250
Cdd:pfam14490 10 IFLQQYGISPALAVKIYKKYGEDALEILKENPYRLAEdiEGIGFKTADKIAR-KLGIAPDSPERIRAGILYVLKQAASNG 88
|
...
gi 1071011108 251 HTY 253
Cdd:pfam14490 89 HTY 91
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
241-719 |
3.11e-97 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 309.98 E-value: 3.11e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 241 FAIHAEVEKGHTYTtQARLrpLLTKLLGDGELAAQAFKAGYHQAQYVLNheaGTYHPTAQLLMETVVAKRLLKLAKQQnr 320
Cdd:COG0507 33 ALLSRAAGEGHTFP-LEDL--AAARLLGVAEDIEAALAALVESGPLVLD---GRRYLTRLLEAEQRLARRLRRLARPA-- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 321 YDESTNAAFLAAV-NELPYELTAMQNEAVLTAL-DNAVSCITGGAGTGKTTVLRTALRAYGKMGFEVHAVALSGRAAMRL 398
Cdd:COG0507 105 LDEADVEAALAALePRAGITLSDEQREAVALALtTRRVSVLTGGAGTGKTTTLRALLAALEALGLRVALAAPTGKAAKRL 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 399 HESIGFKTMTIAALL---------RHEPIEPSDgsPNHLLVIDEASMIDLPTMYRLTNHL-HPAVRIIFTGDPNQLPPIG 468
Cdd:COG0507 185 SESTGIEARTIHRLLglrpdsgrfRHNRDNPLT--PADLLVVDEASMVDTRLMAALLEALpRAGARLILVGDPDQLPSVG 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 469 CGKVLADIVASQAIANVTLDIVKRQKGATGIPEYSMQVNQGLIPEHLSMG--NVYFHETS-KERIAQVCAELYQQSP--- 542
Cdd:COG0507 263 AGAVLRDLIESGTVPVVELTEVYRQADDSRIIELAHAIREGDAPEALNARyaDVVFVEAEdAEEAAEAIVELYADRPagg 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 543 ENSRVVGATTAMVAEINNLIQEAVNPDGarmIFEMYGETYRRNDLRQGDVILFTQNNYEKGIQNGSLGTLTRavgAGDDY 622
Cdd:COG0507 343 EDIQVLAPTNAGVDALNQAIREALNPAG---ELERELAEDGELELYVGDRVMFTRNDYDLGVFNGDIGTVLS---IDEDE 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 623 G--VVELDTGESVYVTQSLLDCMRLGYCITLHKAQGSQFPRIIIAL--QKGRIVDRAWLYTAITRAEHEVHIVGSTAEFA 698
Cdd:COG0507 417 GrlTVRFDGREIVTYDPSELDQLELAYAITVHKSQGSTFDRVILVLpsEHSPLLSRELLYTALTRARELLTLVGDRDALA 496
|
490 500
....*....|....*....|.
gi 1071011108 699 AitkAPSNAHNRNSYLRDLLK 719
Cdd:COG0507 497 R---AVRRDTARATGLAERLR 514
|
|
| recD_rel |
TIGR01448 |
helicase, putative, RecD/TraA family; This model describes a family similar to RecD, the ... |
97-718 |
2.71e-57 |
|
helicase, putative, RecD/TraA family; This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273632 [Multi-domain] Cd Length: 720 Bit Score: 207.71 E-value: 2.71e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 97 PETGEQLIQFIAKEpDFKGIGLGKARALWQLLGEQFHTTLRTDtPE--------SRERLKGILSDVSINALF-NGYAKYK 167
Cdd:TIGR01448 74 PTSKEGIVAYLSSR-SIKGVGKKLAQRIVKTFGEAAFDVLDDD-PEkllevpgiSKANLEKFVSQWSQQGDErRLLAGLQ 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 168 NLShcnwmaecrIPSSIQQRLLKFHGEGSVEAIKDNPYLLVG--FGMEFEEVDTLSQtKFEVELKDPKRLSAALEFA-IH 244
Cdd:TIGR01448 152 GLG---------IGIKLAQRIYKFYQADTLDRVEKDPYLLAEdvKGIGFLTADQLAQ-ALGIALNDPRRITAGLVYSlQQ 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 245 AEVEKGHTYTTQARLRPLLTKLLGDGELAAQAFKAGYHQAQYVLNHEAgtyhptAQLLMETVVAKRLLKLAKQQNRYD-- 322
Cdd:TIGR01448 222 ACTEEGHTYLPRNRFIKQVVHLLNVQPQERLLVPEAVELERLYLDEEP------KLAAEDGRIYLPSLFRAEKQIASHir 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 323 ---ESTNA--------AFLAAVNELPYELTAMQNEAVLTALDNAVSCITGGAGTGKTTVLRTALRAYGKMG--FEVHAVA 389
Cdd:TIGR01448 296 rllATSPAigaindqeHIWEVEKKLRKGLSEEQKQALDTAIQHKVVILTGGPGTGKTTITRAIIELAEELGglLPVGLAA 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 390 LSGRAAMRLHESIGFKTMTIAALLRHEPIEPSDGS-----PNHLLVIDEASMIDLPTMYRLTNHLHPAVRIIFTGDPNQL 464
Cdd:TIGR01448 376 PTGRAAKRLGEVTGLTASTIHRLLGYGPDTFRHNHledpiDCDLLIVDESSMMDTWLALSLLAALPDHARLLLVGDTDQL 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 465 PPIGCGKVLADIVASQAIANVTLDIVKRQKGATGIPEYSMQVNQGLIPE-----HLSMGNVYFHETSKERIAQVcaELYQ 539
Cdd:TIGR01448 456 PSVGPGQVLKDLILSQAIPVTRLTKVYRQAAGSPIITLAHGILHGEAPAwgdfkFLNLTRSEPEGAARHIPLMV--EKIV 533
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 540 QSPENSRVVGA----------TTAMVAEINNLIQEAVNPDGA-RMIFEMYGETYRRndlrqGDVILFTQNNYEKGIQNGS 608
Cdd:TIGR01448 534 GMARVGGIPGAdiqvlapmykGPLGIDALNQHLQALLNPYQKgQGGIEIAEGEYRK-----GDRVMQTKNDYNNEIFNGD 608
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 609 LGTLTRAVGA---GDDYGVVELDTGESVYVTQSLLDcMRLGYCITLHKAQGSQFPRII--IALQKGRIVDRAWLYTAITR 683
Cdd:TIGR01448 609 LGMIVKIEGAkqgKKDQVVVDFDGNEVELTRAELFN-LTLAYATSIHKSQGSEFPTVIlpIHTAHMRMLYRNLLYTALTR 687
|
650 660 670
....*....|....*....|....*....|....*
gi 1071011108 684 AEHEVHIVGSTAEFAAITKapSNAHNRNSYLRDLL 718
Cdd:TIGR01448 688 AKKRVILVGSAEAFDIAAA--RQGQARNTGLLERI 720
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
344-490 |
3.31e-38 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 139.23 E-value: 3.31e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 344 QNEAVLTALDNAVSCITGGAGTGKTTVLRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAALLRHEPIEPSDG 423
Cdd:cd17933 2 QKAAVRLVLRNRVSVLTGGAGTGKTTTLKALLAALEAEGKRVVLAAPTGKAAKRLSESTGIEASTIHRLLGINPGGGGFY 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1071011108 424 ------SPNHLLVIDEASMIDLPTMYRLTNHLHPAVRIIFTGDPNQLPPIGCGKVLADIVASQAIANVTLDIV 490
Cdd:cd17933 82 yneenpLDADLLIVDEASMVDTRLMAALLSAIPAGARLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTEV 154
|
|
| recD |
TIGR01447 |
exodeoxyribonuclease V, alpha subunit; This family describes the exodeoxyribonuclease V alpha ... |
304-702 |
3.22e-36 |
|
exodeoxyribonuclease V, alpha subunit; This family describes the exodeoxyribonuclease V alpha subunit, RecD. RecD is part of a RecBCD complex. A related family in the Gram-positive bacteria separates in a phylogenetic tree, has an additional N-terminal extension of about 200 residues, and is not supported as a member of a RecBCD complex by neighboring genes. The related family is consequently described by a different model. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273631 [Multi-domain] Cd Length: 582 Bit Score: 144.52 E-value: 3.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 304 ETVVAKRLLKLAKQQNRYdesTNAAFLAAVNELPYELtAMQNEAVLTALDNAVSCIT-------GGAGTGKTTVLRTALR 376
Cdd:TIGR01447 113 EEKLAAKLRTLLEARKRT---APSAILENLFPLLNEQ-NWRKTAVALALKSNFSLITggpgtgkTTTVARLLLALVKQSP 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 377 AYGKMgfEVHAVALSGRAAMRLHESIG--FKTM---------------TIAALLRHEPIEPS----DGSPNHL--LVIDE 433
Cdd:TIGR01447 189 KQGKL--RIALAAPTGKAAARLAESLRkaVKNLaaaealiaalpseavTIHRLLGIKPDTKRfrhhERNPLPLdvLVVDE 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 434 ASMIDLPTMYRLTNHLHPAVRIIFTGDPNQLPPIGCGKVLADIV--ASQAIANVTLDIVK-------------------- 491
Cdd:TIGR01447 267 ASMVDLPLMAKLLKALPPNTKLILLGDKNQLPSVEAGAVLGDLCelASIGKSILYALCKKinsktrnplsdnvcflktsh 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 492 RQKGATGIPEYSMQVNQGLIPEHLSMGN------VYFHETSKERIAQVCAELYQQSPENSRVV---GATTAMVAEINNLI 562
Cdd:TIGR01447 347 RFGKDSGIGQLAKAINSGDIEAVLNNLRsgqlieFEFLNSKEDAIERLKNLYVKYRTFLQKLAalsDAKEILETFDRLRL 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 563 QEAVN--PDGA----RMIFEMYGETYRRNDLRQ---GDVILFTQNNYEKGIQNGSLGTLTRavGAGDDYGVVELDTGESV 633
Cdd:TIGR01447 427 LTALRdgPFGVlglnRRIEQELQEKYFDPDEEGwyiGRPIMVTENDYTLGLFNGDIGVLLR--DPDGILTVWFHFADGSK 504
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1071011108 634 YVTQSLLDCMRLGYCITLHKAQGSQFPRIIIALQKG--RIVDRAWLYTAITRAEHEVHIVGSTAEFAAITK 702
Cdd:TIGR01447 505 AVLPSRLPNYETAFAMTVHKSQGSEFDHVILILPNGnsPVLTRELLYTGITRAKDQLSVWSDKETLNAAIK 575
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
367-513 |
2.77e-27 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 109.19 E-value: 2.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 367 KTTVLRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAALLrHEPIEPSDGSPNHLLVIDEASMIDLPTMYRLT 446
Cdd:pfam13604 31 KTTALKALREAWEAAGYRVIGLAPTGRAAKVLGEELGIPADTIAKLL-HRLGGRAGLDPGTLLIVDEAGMVGTRQMARLL 109
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071011108 447 NHLHPA-VRIIFTGDPNQLPPIGCGKVLADIVASQAIAnVTLDIVKRQKgATGIPEYSMQVNQGLIPE 513
Cdd:pfam13604 110 KLAEDAgARVILVGDPRQLPSVEAGGAFRDLLAAGIGT-AELTEIVRQR-DPWQRAASLALRDGDPAE 175
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
344-468 |
1.88e-23 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 96.52 E-value: 1.88e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 344 QNEAVLTALDNAVSCITGGAGTGKTTVLRTALRAYGKMG---FEVHAVALSGRAAMRLHESIGFKTMTIAALLRHEPIEP 420
Cdd:pfam13245 1 QREAVRTALPSKVVLLTGGPGTGKTTTIRHIVALLVALGgvsFPILLAAPTGRAAKRLSERTGLPASTIHRLLGFDDLEA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1071011108 421 -----SDGSPNH--LLVIDEASMIDLPTMYRLTNHLHPAVRIIFTGDPNQLPPIG 468
Cdd:pfam13245 81 ggflrDEEEPLDgdLLIVDEFSMVDLPLAYRLLKALPDGAQLLLVGDPDQLPSVG 135
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
371-683 |
1.42e-16 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 84.36 E-value: 1.42e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 371 LRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAALLR-----HEPIEPSDgspnhLLVIDEASMIDLPTMYRL 445
Cdd:PRK13889 379 LGVAREAWEAAGYEVRGAALSGIAAENLEGGSGIASRTIASLEHgwgqgRDLLTSRD-----VLVIDEAGMVGTRQLERV 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 446 TNHLHPA-VRIIFTGDPNQLPPIGCG---KVLADIVASQAIANVTLDIVKRQKGATgipeysMQVNQGLIPEHL----SM 517
Cdd:PRK13889 454 LSHAADAgAKVVLVGDPQQLQAIEAGaafRSIHERHGGAEIGEVRRQREDWQRDAT------RDLATGRTGEALdayeAH 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 518 GNVYFHETSKERIAQVCAEL---YQQSPENSRVVGA-TTAMVAEINnliqeavnpDGARMIFEMYGE-------TYRRND 586
Cdd:PRK13889 528 GMVHAAATREQARADLIDRWdrdRQAAPDRSRIILThTNDEVRALN---------EAARERMRAAGDlgddvrvTVERGE 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 587 lRQ---GDVILFTQNNYEKGIQNGSLGTLtRAVGAgdDYGVVELDTGESVYVtqSLLDCMRL--GYCITLHKAQGSQFPR 661
Cdd:PRK13889 599 -RSfasGDRVMFLQNERGLGVKNGTLGTI-EQVSA--QSMSVRLDDGRSVAF--DLKDYDRIdhGYAATIHKAQGMTVDR 672
|
330 340
....*....|....*....|..
gi 1071011108 662 IIIALQKGriVDRAWLYTAITR 683
Cdd:PRK13889 673 THVLATPG--MDAHSSYVALSR 692
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
643-692 |
8.05e-14 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 67.20 E-value: 8.05e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1071011108 643 MRLGYCITLHKAQGSQFPRIIIALQKGRIV-DRAWLYTAITRAEHEVHIVG 692
Cdd:cd18809 30 RLQAYAMTIHKSQGSEFDRVIVVLPTSHPMlSRGLLYTALTRARKLLTLVG 80
|
|
| HHH_4 |
pfam14490 |
Helix-hairpin-helix containing domain; This presumed domain contains at least one ... |
173-253 |
2.43e-13 |
|
Helix-hairpin-helix containing domain; This presumed domain contains at least one helix-hairpin-helix motif. This domain is often found in RecD helicases.
Pssm-ID: 464187 [Multi-domain] Cd Length: 91 Bit Score: 65.99 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 173 NWMAECRIPSSIQQRLLKFHGEGSVEAIKDNPYLLVG--FGMEFEEVDTLSQtKFEVELKDPKRLSAALEFAIHAEVEKG 250
Cdd:pfam14490 10 IFLQQYGISPALAVKIYKKYGEDALEILKENPYRLAEdiEGIGFKTADKIAR-KLGIAPDSPERIRAGILYVLKQAASNG 88
|
...
gi 1071011108 251 HTY 253
Cdd:pfam14490 89 HTY 91
|
|
| recD |
PRK10875 |
exodeoxyribonuclease V subunit alpha; |
389-476 |
6.94e-12 |
|
exodeoxyribonuclease V subunit alpha;
Pssm-ID: 236783 [Multi-domain] Cd Length: 615 Bit Score: 68.81 E-value: 6.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 389 ALSGRAAMRLHESIG------------FKTM-----TIAALL---------RHEpiepsDGSPNHL--LVIDEASMIDLP 440
Cdd:PRK10875 206 APTGKAAARLTESLGkalrqlpltdeqKKRIpeeasTLHRLLgaqpgsqrlRYH-----AGNPLHLdvLVVDEASMVDLP 280
|
90 100 110
....*....|....*....|....*....|....*.
gi 1071011108 441 TMYRLTNHLHPAVRIIFTGDPNQLPPIGCGKVLADI 476
Cdd:PRK10875 281 MMARLIDALPPHARVIFLGDRDQLASVEAGAVLGDI 316
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
645-691 |
3.85e-10 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 55.66 E-value: 3.85e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1071011108 645 LGYCITLHKAQGSQFPRIIIAL-----QKGRIVDRAWLYTAITRAEHEVHIV 691
Cdd:pfam13538 1 LAYALTVHKAQGSEFPAVFLVDpdltaHYHSMLRRRLLYTAVTRARKKLVLV 52
|
|
| PRK13826 |
PRK13826 |
Dtr system oriT relaxase; Provisional |
371-698 |
7.59e-09 |
|
Dtr system oriT relaxase; Provisional
Pssm-ID: 237524 [Multi-domain] Cd Length: 1102 Bit Score: 59.41 E-value: 7.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 371 LRTALRAYGKMGFEVHAVALSGRAAMRLHESIGFKTMTIAAL-LRHEpiEPSDGSPNH-LLVIDEASMIDLPTMYRLTNH 448
Cdd:PRK13826 414 MKAAREAWEAAGYRVVGGALAGKAAEGLEKEAGIQSRTLSSWeLRWN--QGRDQLDNKtVFVLDEAGMVASRQMALFVEA 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 449 LHPA-VRIIFTGDPNQLPPIGCGKVLADIVASqaIANVTLDIVKRQKgATGIPEYSMQVNQGLIPEHLSMGNVYFHETSK 527
Cdd:PRK13826 492 VTRAgAKLVLVGDPEQLQPIEAGAAFRAIADR--IGYAELETIYRQR-EQWMRDASLDLARGNVGKALDAYRANGRVIGS 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 528 ERIAQVCAEL-------YQQSpensrvvgATTAMVAEINNLIqeavnpdgaRMIFEMY------------GETYRRND-L 587
Cdd:PRK13826 569 RLKAEAVESLiadwnrdYDPT--------KTTLILAHLRRDV---------RMLNEMAraklvergivgeGHAFRTADgE 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 588 RQ---GDVILFTQNNYEKGIQNGSLGtltRAVGAGDDYGVVELDTGES---VYVTQSLLDCMRLGYCITLHKAQGSQFPR 661
Cdd:PRK13826 632 RRfaaGDQIVFLKNEGSLGVKNGMIG---KVVEAAPNRIVAEIGEGEHrrqVTVEQRFYNNLDHGYATTIHKSQGATVDR 708
|
330 340 350
....*....|....*....|....*....|....*....
gi 1071011108 662 --IIIALQkgriVDRAWLYTAITRAEHEVHIVGSTAEFA 698
Cdd:PRK13826 709 vkVLASLS----LDRHLTYVAMTRHREDLQLYYGRRSFA 743
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
405-467 |
9.91e-09 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 53.78 E-value: 9.91e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1071011108 405 KTMTIAALLRHEPIEPSDG-----SPNH-------LLVIDEASMIDLPTmyrLTNHLHPAVRIIFTGDPNQLPPI 467
Cdd:cd17934 12 KTTTIAAIVLQLLKGLRGKrvlvtAQSNvavdnvdVVIIDEASQITEPE---LLIALIRAKKVVLVGDPKQLPPV 83
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
621-692 |
1.83e-08 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 52.05 E-value: 1.83e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071011108 621 DYGVVELDTGESVYVTQSLLDCMR------LGYCITLHKAQGSQFPRIIIALQKGRIVDRAWLYTAITRAEHEVHIVG 692
Cdd:cd18786 12 KGVVLTPYHRDRAYLNQYLQGLSLdefdlqLVGAITIDSSQGLTFDVVTLYLPTANSLTPRRLYVALTRARKRLVIYD 89
|
|
| TraI_TIGR |
TIGR02760 |
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ... |
226-493 |
1.97e-06 |
|
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.
Pssm-ID: 274285 [Multi-domain] Cd Length: 1960 Bit Score: 51.44 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 226 EVELKDPKrLSAALEFAIHAEVEKG----------HTY------TTQARLRPLLTKLLGDGELAAQAFKAGYHQAQYVLN 289
Cdd:TIGR02760 902 EAKAKDGK-NSIALQYALEKVSEKEaafkqkelvtEAYvfafeeTGFAIKAAEIAAALKNRPKLYRLLSAEYGDGTRWTT 980
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 290 HEAgtyhptaqLLMETVVakrLLKLAKQQNRYDESTNAAFLAAVNELPYELTAMQNEA---VLTALDNAVScITGGAGTG 366
Cdd:TIGR02760 981 RAA--------LRTETSI---LLHILPGKETVTPLATRAQVFLNLELLERLTHGQKQAihlIISTKDRFVA-VQGLAGVG 1048
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 367 KTTVLRTALRAYGKMG----FEVHAVALSGRAAMRLhESIGFKTMTIAALL---RHEPIEPSDGSpNHLLVIDEASMIDL 439
Cdd:TIGR02760 1049 KTTMLESRYKPVLQAFeseqLQVIGLAPTHEAVGEL-KSAGVQAQTLDSFLtdiSLYRNSGGDFR-NTLFILDESSMVSN 1126
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1071011108 440 PTMYRLTN-HLHPAVRIIFTGDPNQLPPIGCGKVLADIVASQAIANVTLDIVKRQ 493
Cdd:TIGR02760 1127 FQLTHATElVQKSGSRAVSLGDIAQLQSLAAGKPFELAITFDIIDTAIMKEIVRQ 1181
|
|
| DNA2 |
COG1112 |
Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]; |
386-467 |
5.66e-06 |
|
Superfamily I DNA and/or RNA helicase [Replication, recombination and repair];
Pssm-ID: 440729 [Multi-domain] Cd Length: 819 Bit Score: 49.74 E-value: 5.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 386 HAVALSGRAAMRLHESIGfktMTIAALLRHEPIEPS--DgspnhLLVIDEASMIDLPT----MYRltnhlhpAVRIIFTG 459
Cdd:COG1112 522 ELRKLLWDALLELAPVVG---MTPASVARLLPLGEGsfD-----LVIIDEASQATLAEalgaLAR-------AKRVVLVG 586
|
....*...
gi 1071011108 460 DPNQLPPI 467
Cdd:COG1112 587 DPKQLPPV 594
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
405-480 |
6.90e-06 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 45.94 E-value: 6.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071011108 405 KTMT----IAALLRHEPIE--------PSDGSPNHL--LVIDEASMIDLPTMYRLTNHLHPAVRIIFTGDPNQLPPIGCG 470
Cdd:cd17914 12 KTRVlvkiVAALMQNKNGEpgrillvtPTNKAAAQLdnILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRG 91
|
90
....*....|
gi 1071011108 471 KVLADIVASQ 480
Cdd:cd17914 92 AVLAKICNEQ 101
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
649-716 |
3.12e-03 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 41.10 E-value: 3.12e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1071011108 649 ITLHKAQGSQFPRIIIALQKGRIVDRAW------LYTAITRAEHEVHIVGStaefaaitKAPSNAHNRNSYLRD 716
Cdd:COG1074 648 MTIHKSKGLEFPVVFLPALRERARAEELaeelrlLYVALTRARDRLVLSGA--------VKKKDAEKESSWLAR 713
|
|
| DEXXQc_SF1 |
cd18043 |
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ... |
428-466 |
4.08e-03 |
|
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350801 [Multi-domain] Cd Length: 127 Bit Score: 37.95 E-value: 4.08e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1071011108 428 LLVIDEASMID----LPTMYRltnhlhpAVRIIFTGDPNQLPP 466
Cdd:cd18043 83 LVIFDEASQIPieeaLPALFR-------GKQVVVVGDDKQLPP 118
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
650-707 |
6.23e-03 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 39.82 E-value: 6.23e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1071011108 650 TLHKAQGSQFPRIIIA----LQKG--RIVDRAWLYTAITRAEHEVHIVGSTAEFAAITKAPSNA 707
Cdd:COG3972 493 TIHRAKGLEAPVVIIVgldqLAKGesLERLRNLLYVAMTRARGWLVVSGSGESMAELYDELREV 556
|
|
| |
