NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1071014626|ref|WP_069788359|]
View 

FAD-dependent oxidoreductase [Pseudomonas salomonii]

Protein Classification

flavin monoamine oxidase family protein( domain architecture ID 11440890)

flavin monoamine oxidase family protein functions as an oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60|1.10.405.10
EC:  1.-.-.-
Gene Ontology:  GO:0000166|GO:0016491
SCOP:  4000128

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
48-516 3.54e-94

Monoamine oxidase [Amino acid transport and metabolism];


:

Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 293.75  E-value: 3.54e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  48 GQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRNGdrvdykdgrtqtvafDNGLYFNAGPARIPSQH 127
Cdd:COG1231     5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFG---------------DDGLYAELGAMRIPPSH 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 128 RTILDYCSELGVPLEVLVNSSHGAQVrpDLQQSAFTVGQAINDTRGhLSGLLAKAVqrDALDDVLSS-------EERTRL 200
Cdd:COG1231    70 TNLLALARELGLPLEPFPNENGNALL--YLGGKRVRAGEIAADLRG-VAELLAKLL--RALAAALDPwahpaaeLDRESL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 201 LAFLQVYGDLSQELAFEGSLRsghlespahPGALPASRSPLGLGRLLHPELWGallhtefpEFSATMFQPVGGMDRITDA 280
Cdd:COG1231   145 AEWLRRNGASPSARRLLGLLG---------AGEYGADPDELSLLDLLRYAASA--------GGGAQQFRIVGGMDQLPRA 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 281 FYQRVREHVQLGAQVRQIRQLEDGVAVTYhdqlsGREQVVRADYLVSTLPLPLLAKLDTD--FSDPVKAALLSTRSDQAT 358
Cdd:COG1231   208 LAAELGDRIRLGAPVTRIRQDGDGVTVTT-----DDGGTVRADAVIVTVPPSVLRRIEFDppLPAAKRAAIQRLPYGAAI 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 359 KVAWQSP-RFWETDYRtYGGLSWIEHPARLLWYPSNDLNTRDGLLVaGYVTGEGADVFGAKPFDQQYATSKEAVELLHPG 437
Cdd:COG1231   283 KVFLQFDrPFWEEDGL-YGGISLTDLPIRQTWYPSNGPDGGAGVLL-GYVGGDDARALAALSPEERVAAALEQLARIFGV 360

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 438 YSKHLRHPLAVSWEQIPYSEGPW------LQREHFPAdasalLEQAHGRVYFAGDGLVQSGVGiWQESAANSARHVIAQL 511
Cdd:COG1231   361 YAAEPVDYVSTDWGRDPWSRGAYaaappgQLTAAGPA-----LAEPDGRIHFAGEHTSDEWPG-WVEGALESGERAAAEI 434


                  ....*
gi 1071014626 512 AERVT 516
Cdd:COG1231   435 LARLG 439
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
48-516 3.54e-94

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 293.75  E-value: 3.54e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  48 GQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRNGdrvdykdgrtqtvafDNGLYFNAGPARIPSQH 127
Cdd:COG1231     5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFG---------------DDGLYAELGAMRIPPSH 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 128 RTILDYCSELGVPLEVLVNSSHGAQVrpDLQQSAFTVGQAINDTRGhLSGLLAKAVqrDALDDVLSS-------EERTRL 200
Cdd:COG1231    70 TNLLALARELGLPLEPFPNENGNALL--YLGGKRVRAGEIAADLRG-VAELLAKLL--RALAAALDPwahpaaeLDRESL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 201 LAFLQVYGDLSQELAFEGSLRsghlespahPGALPASRSPLGLGRLLHPELWGallhtefpEFSATMFQPVGGMDRITDA 280
Cdd:COG1231   145 AEWLRRNGASPSARRLLGLLG---------AGEYGADPDELSLLDLLRYAASA--------GGGAQQFRIVGGMDQLPRA 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 281 FYQRVREHVQLGAQVRQIRQLEDGVAVTYhdqlsGREQVVRADYLVSTLPLPLLAKLDTD--FSDPVKAALLSTRSDQAT 358
Cdd:COG1231   208 LAAELGDRIRLGAPVTRIRQDGDGVTVTT-----DDGGTVRADAVIVTVPPSVLRRIEFDppLPAAKRAAIQRLPYGAAI 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 359 KVAWQSP-RFWETDYRtYGGLSWIEHPARLLWYPSNDLNTRDGLLVaGYVTGEGADVFGAKPFDQQYATSKEAVELLHPG 437
Cdd:COG1231   283 KVFLQFDrPFWEEDGL-YGGISLTDLPIRQTWYPSNGPDGGAGVLL-GYVGGDDARALAALSPEERVAAALEQLARIFGV 360

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 438 YSKHLRHPLAVSWEQIPYSEGPW------LQREHFPAdasalLEQAHGRVYFAGDGLVQSGVGiWQESAANSARHVIAQL 511
Cdd:COG1231   361 YAAEPVDYVSTDWGRDPWSRGAYaaappgQLTAAGPA-----LAEPDGRIHFAGEHTSDEWPG-WVEGALESGERAAAEI 434


                  ....*
gi 1071014626 512 AERVT 516
Cdd:COG1231   435 LARLG 439
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 60-508 1.68e-33

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 132.23  E-value: 1.68e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  60 IAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRngdrvdykdgrtqtvafDNGLYFNAGPARIPSQHRTILDYCSELGV 139
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVR-----------------DDGFLIELGAMWFHGAQPPLLALLKELGL 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 140 PLEVLVNSSHG--AQVRPDLQQSAFTV---------------GQAINDTRGHLSGLLAKAVQRDALDDVLSSEERTRLLA 202
Cdd:pfam01593  64 EDRLVLPDPAPfyTVLFAGGRRYPGDFrrvpagwegllefgrLLSIPEKLRLGLAALASDALDEFDLDDFSLAESLLFLG 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 203 FLQvygdLSQELAFEGSLRSGHLESPAHPGALPASRSPLGLGRLLHPELWGALlhtefpEFSATMFQPVGGMDRITDAFY 282
Cdd:pfam01593 144 RRG----PGDVEVWDRLIDPELFAALPFASGAFAGDPSELSAGLALPLLWALL------GEGGSLLLPRGGLGALPDALA 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 283 QRVRE-HVQLGAQVRQIRQLEDGVAVTYHDQlsgreQVVRADYLVSTLPLPLLA--KLDTDFSDPVKAALLSTRSDQATK 359
Cdd:pfam01593 214 AQLLGgDVRLNTRVRSIDREGDGVTVTLTDG-----EVIEADAVIVTVPLGVLKriLFTPPLPPEKARAIRNLGYGPVNK 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 360 V-AWQSPRFWETD-YRTYGGLSWIEHPARLLWYPSNDLNTRD-GLLVAGYVTGEGADVFGAKPFDQQYAtsKEAVELLHP 436
Cdd:pfam01593 289 VhLEFDRKFWPDLgLLGLLSELLTGLGTAFSWLTFPNRAPPGkGLLLLVYVGPGDRARELEGLSDEELL--QAVLRDLRK 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 437 GYSKHLRHPLAV---SWEQIPYSEGPWLQREHFP--ADASALLEQAHGRVYFAGD-------GLVQSGVgiwqESAANSA 504
Cdd:pfam01593 367 LFGEEAPEPLRVlvsDWHTDPWPRGSYSLPQYGPghDDYRPLARTPDPGLFFAGEhtstgypGTVEGAI----ESGRRAA 442


                  ....
gi 1071014626 505 RHVI 508
Cdd:pfam01593 443 RAVL 446
PLN02976 PLN02976
amine oxidase
 50-147 7.86e-12

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 68.36  E-value: 7.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626   50 GTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTlrngDRVdykdgrTQTVAFDNGLYFNAG-PARIPSQHR 128
Cdd:PLN02976   693 RKKIIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYT----DRS------SLSVPVDLGASIITGvEADVATERR 762

                           90       100
                   ....*....|....*....|..
gi 1071014626  129 ---TILdYCSELGVPLEVLvNS 147
Cdd:PLN02976   763 pdpSSL-ICAQLGLELTVL-NS 782
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 53-120 6.04e-07

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 51.89  E-value: 6.04e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRngdrvdykdgrtqtvafDNGLYFNAGP 120
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE-----------------DDGFRFDTGP 51
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
48-516 3.54e-94

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 293.75  E-value: 3.54e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  48 GQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRNGdrvdykdgrtqtvafDNGLYFNAGPARIPSQH 127
Cdd:COG1231     5 ARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFG---------------DDGLYAELGAMRIPPSH 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 128 RTILDYCSELGVPLEVLVNSSHGAQVrpDLQQSAFTVGQAINDTRGhLSGLLAKAVqrDALDDVLSS-------EERTRL 200
Cdd:COG1231    70 TNLLALARELGLPLEPFPNENGNALL--YLGGKRVRAGEIAADLRG-VAELLAKLL--RALAAALDPwahpaaeLDRESL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 201 LAFLQVYGDLSQELAFEGSLRsghlespahPGALPASRSPLGLGRLLHPELWGallhtefpEFSATMFQPVGGMDRITDA 280
Cdd:COG1231   145 AEWLRRNGASPSARRLLGLLG---------AGEYGADPDELSLLDLLRYAASA--------GGGAQQFRIVGGMDQLPRA 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 281 FYQRVREHVQLGAQVRQIRQLEDGVAVTYhdqlsGREQVVRADYLVSTLPLPLLAKLDTD--FSDPVKAALLSTRSDQAT 358
Cdd:COG1231   208 LAAELGDRIRLGAPVTRIRQDGDGVTVTT-----DDGGTVRADAVIVTVPPSVLRRIEFDppLPAAKRAAIQRLPYGAAI 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 359 KVAWQSP-RFWETDYRtYGGLSWIEHPARLLWYPSNDLNTRDGLLVaGYVTGEGADVFGAKPFDQQYATSKEAVELLHPG 437
Cdd:COG1231   283 KVFLQFDrPFWEEDGL-YGGISLTDLPIRQTWYPSNGPDGGAGVLL-GYVGGDDARALAALSPEERVAAALEQLARIFGV 360

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 438 YSKHLRHPLAVSWEQIPYSEGPW------LQREHFPAdasalLEQAHGRVYFAGDGLVQSGVGiWQESAANSARHVIAQL 511
Cdd:COG1231   361 YAAEPVDYVSTDWGRDPWSRGAYaaappgQLTAAGPA-----LAEPDGRIHFAGEHTSDEWPG-WVEGALESGERAAAEI 434


                  ....*
gi 1071014626 512 AERVT 516
Cdd:COG1231   435 LARLG 439
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 60-508 1.68e-33

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 132.23  E-value: 1.68e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  60 IAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRngdrvdykdgrtqtvafDNGLYFNAGPARIPSQHRTILDYCSELGV 139
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVR-----------------DDGFLIELGAMWFHGAQPPLLALLKELGL 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 140 PLEVLVNSSHG--AQVRPDLQQSAFTV---------------GQAINDTRGHLSGLLAKAVQRDALDDVLSSEERTRLLA 202
Cdd:pfam01593  64 EDRLVLPDPAPfyTVLFAGGRRYPGDFrrvpagwegllefgrLLSIPEKLRLGLAALASDALDEFDLDDFSLAESLLFLG 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 203 FLQvygdLSQELAFEGSLRSGHLESPAHPGALPASRSPLGLGRLLHPELWGALlhtefpEFSATMFQPVGGMDRITDAFY 282
Cdd:pfam01593 144 RRG----PGDVEVWDRLIDPELFAALPFASGAFAGDPSELSAGLALPLLWALL------GEGGSLLLPRGGLGALPDALA 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 283 QRVRE-HVQLGAQVRQIRQLEDGVAVTYHDQlsgreQVVRADYLVSTLPLPLLA--KLDTDFSDPVKAALLSTRSDQATK 359
Cdd:pfam01593 214 AQLLGgDVRLNTRVRSIDREGDGVTVTLTDG-----EVIEADAVIVTVPLGVLKriLFTPPLPPEKARAIRNLGYGPVNK 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 360 V-AWQSPRFWETD-YRTYGGLSWIEHPARLLWYPSNDLNTRD-GLLVAGYVTGEGADVFGAKPFDQQYAtsKEAVELLHP 436
Cdd:pfam01593 289 VhLEFDRKFWPDLgLLGLLSELLTGLGTAFSWLTFPNRAPPGkGLLLLVYVGPGDRARELEGLSDEELL--QAVLRDLRK 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 437 GYSKHLRHPLAV---SWEQIPYSEGPWLQREHFP--ADASALLEQAHGRVYFAGD-------GLVQSGVgiwqESAANSA 504
Cdd:pfam01593 367 LFGEEAPEPLRVlvsDWHTDPWPRGSYSLPQYGPghDDYRPLARTPDPGLFFAGEhtstgypGTVEGAI----ESGRRAA 442


                  ....
gi 1071014626 505 RHVI 508
Cdd:pfam01593 443 RAVL 446
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 51-349 3.27e-22

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 99.14  E-value: 3.27e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLR-NGDRVDYkdgrtqtvafdnglyfnaGPARIPSQHRT 129
Cdd:COG1232     2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEvDGFRIDR------------------GPHSFLTRDPE 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 130 ILDYCSELGVPLEVLVNSSHGAQVR--------PDLQQSAFtvgqaindTRGHLS-------GLLAKAVQRDALDDVlSS 194
Cdd:COG1232    64 VLELLRELGLGDELVWPNTRKSYIYyggklhplPQGPLALL--------RSPLLSlagklraLLELLAPRRPPGEDE-SL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 195 EE--RTRL---------LAFLQ-VYGDLSQELafegSLRSghlespAHPGALPASRSPLGLgrllhpeLWGALLHTEFPE 262
Cdd:COG1232   135 AEfvRRRFgrevyerlvEPLLEgVYAGDPDEL----SADW------AFPRLKRLELEHGSL-------IKGALALRKGAK 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 263 FSATMFQPVGGMDRITDAFYQRVRE-HVQLGAQVRQIRQLEDGVAVTYHDqlsgrEQVVRADYLVSTLPLPLLAKLDTDF 341
Cdd:COG1232   198 AGEVFGYLRGGLGTLVEALAEALEAgEIRLGTRVTAIEREGGGWRVTTSD-----GETIEADAVVSATPAPALARLLAPL 272


                  ....*...
gi 1071014626 342 SDPVKAAL 349
Cdd:COG1232   273 PPEVAAAL 280
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 52-336 1.38e-14

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 76.04  E-value: 1.38e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTwtlrngdRVDYKDGRTqtvafdnglyFNAGPARI--PSQHRT 129
Cdd:COG1233     5 DVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRA-------RTFERPGFR----------FDVGPSVLtmPGVLER 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 130 ILDYCsELGVPLEVLVNSSHGAQVRPDlqQSAFTVGQAINDTRGHLSGLLAKAVQR------------DALDDVLSSEER 197
Cdd:COG1233    68 LFREL-GLEDYLELVPLDPAYRVPFPD--GRALDLPRDLERTAAELERLFPGDAEAyrrflaelrrlyDALLEDLLYRPL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 198 TRLLAFLQVYGDLSQELAFEGSLR---SGHLESPAHPGALpaSRSPLGLGrlLHPELWGALLHTE-FPEFSATMFQPVGG 273
Cdd:COG1233   145 LSLRDLLRPLALARLLRLLLRSLRdllRRYFKDPRLRALL--AGQALYLG--LSPDRTPALYALIaYLEYAGGVWYPKGG 220

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071014626 274 MDRITDAFYQRVREH---VQLGAQVRQIRqLEDGVA--VTYHDqlsGREqvVRADYLVSTLPLPLLAK 336
Cdd:COG1233   221 MGALADALARLAEELggeIRTGAEVERIL-VEGGRAtgVRLAD---GEE--IRADAVVSNADPAHTYL 282
PLN02976 PLN02976
amine oxidase
 50-147 7.86e-12

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 68.36  E-value: 7.86e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626   50 GTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTlrngDRVdykdgrTQTVAFDNGLYFNAG-PARIPSQHR 128
Cdd:PLN02976   693 RKKIIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYT----DRS------SLSVPVDLGASIITGvEADVATERR 762

                           90       100
                   ....*....|....*....|..
gi 1071014626  129 ---TILdYCSELGVPLEVLvNS 147
Cdd:PLN02976   763 pdpSSL-ICAQLGLELTVL-NS 782
PLN03000 PLN03000
amine oxidase
 39-419 1.38e-11

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 67.35  E-value: 1.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  39 QPLKLK-PGLGQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWT--LRNGDRVDYKD--GRTQTVAFDNG 113
Cdd:PLN03000  172 QAIKDKfPAQSSKSSVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTkkMEANRVGAAADlgGSVLTGTLGNP 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 114 LYFNAgpARIPSQHRTILDYCselgvPLEvlvnSSHGAQVRPDLQqsaFTVGQAINDtrghlsgLLAKAVQ-RDALDDV- 191
Cdd:PLN03000  252 LGIIA--RQLGSSLYKVRDKC-----PLY----RVDGKPVDPDVD---LKVEVAFNQ-------LLDKASKlRQLMGDVs 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 192 LSSEERTRLLAFLQVYG-DLSQElafEGSLRSGHLESPAHPGALPASRSPLGLGRLLHPELWGAlLHTEFPefsatmfqp 270
Cdd:PLN03000  311 MDVSLGAALETFRQVSGnDVATE---EMGLFNWHLANLEYANAGLVSKLSLAFWDQDDPYDMGG-DHCFLP--------- 377

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 271 vGGMDRITDAFYQRVRehVQLGAQVRQIRQLEDGVAVTyhdqlsGREQVVRADYLVSTLPLPLLAKLDTDFSDPVKAALL 350
Cdd:PLN03000  378 -GGNGRLVQALAENVP--ILYEKTVQTIRYGSNGVKVI------AGNQVYEGDMVLCTVPLGVLKNGSIKFVPELPQRKL 448

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071014626 351 STRSDQA----TKVAWQSPR-FWETDYRTYGGLSwiEHPAR----LLWYPSNDLntRDGLLVAGYVTGEGADVFGAKP 419
Cdd:PLN03000  449 DCIKRLGfgllNKVAMLFPYvFWSTDLDTFGHLT--EDPNYrgefFLFYSYAPV--AGGPLLIALVAGEAAHKFETMP 522
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
55-100 1.81e-10

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 56.77  E-value: 1.81e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1071014626  55 VLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLR-NGDRVDY 100
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRvPGYVFDY 47
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 50-139 2.57e-10

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 62.56  E-value: 2.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  50 GTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRT--WTLRNGDRVdykdgrtqtvaFDNGLYFnagparIPSQH 127
Cdd:COG3349     3 PPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGGRArsFPDPDTGLP-----------IDNGQHV------LLGCY 65

                          90
                  ....*....|..
gi 1071014626 128 RTILDYCSELGV 139
Cdd:COG3349    66 RNTLDLLRRIGA 77
PRK07208 PRK07208
hypothetical protein; Provisional
 49-100 1.01e-08

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 57.59  E-value: 1.01e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1071014626  49 QGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG--RTWTlRNGDRVDY 100
Cdd:PRK07208    3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGisRTVT-YKGNRFDI 55
PLN02529 PLN02529
lysine-specific histone demethylase 1
 45-486 1.98e-08

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 57.21  E-value: 1.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  45 PGLGQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRNGDRvdykdGRTQTVafdnglyfNAGPARIP 124
Cdd:PLN02529  155 PEEGTEGSVIIVGAGLAGLAAARQLLSFGFKVVVLEGRNRPGGRVYTQKMGRK-----GQFAAV--------DLGGSVIT 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 125 SQHRTILDYCS-ELGVPLEVLVNS-----SHGAQVRPDLQQSAFTVGQAINDTRGHLSGLLAKAVQRDALDDVLsseERT 198
Cdd:PLN02529  222 GIHANPLGVLArQLSIPLHKVRDNcplykPDGALVDKEIDSNIEFIFNKLLDKVTELRQIMGGFANDISLGSVL---ERL 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 199 RllaflQVYGdlSQELAFEGSLRSGHLESPAHPGAlpasrsplGLGRLLHPELWGallHTEFPEFSATMFQPVGGMDRIT 278
Cdd:PLN02529  299 R-----QLYG--VARSTEERQLLDWHLANLEYANA--------GCLSDLSAAYWD---QDDPYEMGGDHCFLAGGNWRLI 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 279 DAFYQRVRehVQLGAQVRQIRQLEDGVAVtyhdqLSGrEQVVRADYLVSTLPLPLLAKLDTDFSD--PVK--AALLSTRS 354
Cdd:PLN02529  361 NALCEGVP--IFYGKTVDTIKYGNDGVEV-----IAG-SQVFQADMVLCTVPLGVLKKRTIRFEPelPRRklAAIDRLGF 432

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 355 DQATKVAWQSPR-FWETDYRTYGGLSwiEHPAR----LLWYPSNDLNtrDGLLVAGYVTGEGADVFgakpfdqqyaTSKE 429
Cdd:PLN02529  433 GLLNKVAMVFPSvFWGEELDTFGCLN--ESSNKrgefFLFYGYHTVS--GGPALVALVAGEAAQRF----------ENTD 498

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1071014626 430 AVELLHPGYSKhLR--------------HPLAVSWEQIPYSEGPW--LQREHFPADASALLEQAHGRVYFAGD 486
Cdd:PLN02529  499 PSTLLHRVLSV-LRgiynpkginvpdpiQTICTRWGSDPLSYGSYshVRVQSSGSDYDILAESVSGRLFFAGE 570
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 51-133 3.26e-08

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 55.64  E-value: 3.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGrTWTLRNgdrvdYKDGRTQTVAFDNGLYF---NAGPARIPSQH 127
Cdd:COG2072     7 VDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGG-TWRDNR-----YPGLRLDTPSHLYSLPFfpnWSDDPDFPTGD 80


                  ....*.
gi 1071014626 128 RtILDY 133
Cdd:COG2072    81 E-ILAY 85
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 3-98 9.28e-08

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 55.00  E-value: 9.28e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626   3 LTRREALSSIAAvgGEKAVKD-ALAVL--------GLGPSShrRPQPLKLKPGLgQGTRVLVLGAGIAGLVTALELSRAG 73
Cdd:PLN02328  187 LTRDHALESIRA--EHKNLVDsAYNFLlehgyinfGVAPVI--KEAQLRSFEGV-EPANVVVVGAGLAGLVAARQLLSMG 261

                          90       100
                  ....*....|....*....|....*.
gi 1071014626  74 FSVQVLEARNRVGGRTWTLR-NGDRV 98
Cdd:PLN02328  262 FKVVVLEGRARPGGRVKTMKmKGDGV 287
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
51-100 1.08e-07

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 53.73  E-value: 1.08e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRNGD-RVDY 100
Cdd:COG3380     4 PDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGgRFDH 54
PRK07233 PRK07233
hypothetical protein; Provisional
 52-87 1.10e-07

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 54.12  E-value: 1.10e-07
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:PRK07233    1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGG 36
PLN02268 PLN02268
probable polyamine oxidase
 53-91 1.77e-07

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 53.54  E-value: 1.77e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWT 91
Cdd:PLN02268    3 VIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHT 41
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 53-120 6.04e-07

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 51.89  E-value: 6.04e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRngdrvdykdgrtqtvafDNGLYFNAGP 120
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE-----------------DDGFRFDTGP 51
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 52-95 1.02e-06

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 50.86  E-value: 1.02e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTwTLRNG 95
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGA-SGRNA 43
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
51-95 1.55e-06

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 50.29  E-value: 1.55e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEaRNRVGGRTwTLRNG 95
Cdd:COG0665     3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLE-RGRPGSGA-SGRNA 45
PLN02576 PLN02576
protoporphyrinogen oxidase
 39-114 1.95e-06

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 50.40  E-value: 1.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  39 QPLKLKPGLGQGTRVLVLGAGIAGLVTALEL-SRAGFSVQVLEARNRVGGRTWTLRNGDRVdYKDGRTQ--------TVA 109
Cdd:PLN02576    1 SAIAEGSAAASSKDVAVVGAGVSGLAAAYALaSKHGVNVLVTEARDRVGGNITSVSEDGFI-WEEGPNSfqpsdpelTSA 79


                  ....*
gi 1071014626 110 FDNGL 114
Cdd:PLN02576   80 VDSGL 84
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 51-92 4.06e-06

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 48.78  E-value: 4.06e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTL 92
Cdd:COG0654     4 TDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGI 45
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
51-90 7.19e-06

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 48.64  E-value: 7.19e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVL--EARNRVGGRTW 90
Cdd:COG3573     6 ADVIVVGAGLAGLVAAAELADAGRRVLLLdqEPEANLGGQAF 47
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
52-88 7.90e-06

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 48.70  E-value: 7.90e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGR 88
Cdd:COG1148   142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGR 178
PLN02487 PLN02487
zeta-carotene desaturase
 31-99 1.70e-05

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 47.49  E-value: 1.70e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1071014626  31 GPSSHRRPqplKLKpglgqgtrVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGR--TWTLRNGDRVD 99
Cdd:PLN02487   67 EPEAYKGP---KLK--------VAIIGAGLAGMSTAVELLDQGHEVDIYESRPFIGGKvgSFVDKNGNHIE 126
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 35-95 4.38e-05

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 45.90  E-value: 4.38e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1071014626  35 HRRPQPLKLKPGLGQgtRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGrtwTLRNG 95
Cdd:COG0493   108 EGWVKPPPPAPRTGK--KVAVVGSGPAGLAAAYQLARAGHEVTVFEALDKPGG---LLRYG 163
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 32-86 4.44e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 46.38  E-value: 4.44e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1071014626  32 PSSHRRPQPLKLKPGLGQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVG 86
Cdd:PRK01747  242 TLPAPLAAPWFARPGSPKARDAAIIGGGIAGAALALALARRGWQVTLYEADEAPA 296
PTZ00306 PTZ00306
NADH-dependent fumarate reductase; Provisional
 52-144 6.04e-05

NADH-dependent fumarate reductase; Provisional


Pssm-ID: 140327 [Multi-domain]  Cd Length: 1167  Bit Score: 45.93  E-value: 6.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626   52 RVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRTWTLRNGdrVDYKDGRTQTVA--FDNGLYFN-------AGPAR 122
Cdd:PTZ00306   411 RVIVVGGGLAGCSAAIEAASCGAQVILLEKEAKLGGNSAKATSG--INGWGTRAQAKQdvLDGGKFFErdthlsgKGGHC 488

                           90       100
                   ....*....|....*....|....*....
gi 1071014626  123 IPSQHRTI-------LDYCSELGVPLEVL 144
Cdd:PTZ00306   489 DPGLVKTLsvksadaISWLSSLGVPLTVL 517
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 44-87 9.35e-05

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 44.78  E-value: 9.35e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1071014626  44 KPGLGQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:PRK11749  134 KRAPKTGKKVAVIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG 177
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 53-87 9.89e-05

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 44.85  E-value: 9.89e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:PLN02172   13 VAVIGAGAAGLVAARELRREGHTVVVFEREKQVGG 47
PRK07538 PRK07538
hypothetical protein; Provisional
 51-81 1.01e-04

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 44.89  E-value: 1.01e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEA 81
Cdd:PRK07538    1 MKVLIAGGGIGGLTLALTLHQRGIEVVVFEA 31
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 44-87 1.04e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 44.87  E-value: 1.04e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1071014626  44 KPGLGQGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:PRK12771  131 APAPDTGKRVAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGG 174
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 50-87 1.26e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 44.38  E-value: 1.26e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1071014626  50 GTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:PRK12810  143 GKKVAVVGSGPAGLAAADQLARAGHKVTVFERADRIGG 180
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
49-80 1.88e-04

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 43.87  E-value: 1.88e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1071014626  49 QGTRVLVLGAGIAGLVTALELSRAGFSVQVLE 80
Cdd:PRK08163    3 KVTPVLIVGGGIGGLAAALALARQGIKVKLLE 34
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 53-87 1.94e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 44.05  E-value: 1.94e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:COG1053     6 VVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGG 40
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 53-90 2.08e-04

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 44.12  E-value: 2.08e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVL--EARNRVGGRTW 90
Cdd:PRK12834    7 VIVVGAGLAGLVAAAELADAGKRVLLLdqENEANLGGQAF 46
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 52-352 2.43e-04

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 43.68  E-value: 2.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQ--VLEARNRVGgrtwtlrngdrvdykdGRTQTVAFDNGLyFNAGP----ARIPS 125
Cdd:PRK11883    2 KVAIIGGGITGLSAAYRLHKKGPDADitLLEASDRLG----------------GKIQTVRKDGFP-IELGPesflARKPS 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 126 qhrtILDYCSELGvpLE-VLVNSSHG----------------------AQVRPDLQQSAF---TVGQAINDTRghlsgLL 179
Cdd:PRK11883   65 ----APALVKELG--LEdELVANTTGqsyiyvngklhpippgtvmgipTSIAPFLFAGLVspiGKLRAAADLR-----PP 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 180 AKAVQRD-ALDDV----LSSEERTRLLAFLQ--VYGDLSQELafegSLRSghlespahpgALPAsrsplgLGRLL--HPE 250
Cdd:PRK11883  134 RWKPGQDqSVGAFfrrrFGDEVVENLIEPLLsgIYAGDIDTL----SLRA----------TFPQ------LAQAEdkYGS 193

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1071014626 251 LWGALLHTEFPEFSAT--MFQPV-GGMDRITDAFYQRVR-EHVQLGAQVRQIRQLEDGVAVTYHDQlsgreQVVRADYLV 326
Cdd:PRK11883  194 LLRGMRKALPKEKKKTkgVFGTLkGGLQSLIEALEEKLPaGTIHKGTPVTKIDKSGDGYEIVLSNG-----GEIEADAVI 268

                         330       340
                  ....*....|....*....|....*.
gi 1071014626 327 STLPLPLLAKLdtdFSDPVKAALLST 352
Cdd:PRK11883  269 VAVPHPVLPSL---FVAPPAFALFKT 291
PRK06847 PRK06847
hypothetical protein; Provisional
 52-87 2.66e-04

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 43.32  E-value: 2.66e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQVLEAR--NRVGG 87
Cdd:PRK06847    6 KVLIVGGGIGGLSAAIALRRAGIAVDLVEIDpeWRVYG 43
PLN02568 PLN02568
polyamine oxidase
 52-99 2.69e-04

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 43.66  E-value: 2.69e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAG-----FSVQVLEARNRVGGRTWTLR-NGDRVD 99
Cdd:PLN02568    7 RIVIIGAGMAGLTAANKLYTSSaandmFELTVVEGGDRIGGRINTSEfGGERIE 60
PLN02612 PLN02612
phytoene desaturase
 33-96 3.71e-04

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 43.29  E-value: 3.71e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1071014626  33 SSHRRPQPLKLKPglgqgTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGR--TWTLRNGD 96
Cdd:PLN02612   81 SASFRSAPRPAKP-----LKVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKvaAWKDEDGD 141
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 51-84 3.81e-04

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 43.09  E-value: 3.81e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEaRNR 84
Cdd:PRK12409    2 SHIAVIGAGITGVTTAYALAQRGYQVTVFD-RHR 34
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
51-92 8.21e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 41.64  E-value: 8.21e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEaRNRVGGRTWTL 92
Cdd:COG0492     1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIE-GGEPGGQLATT 41
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 51-90 9.05e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 41.53  E-value: 9.05e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEA-RNRVGGRTW 90
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDeGTCPYGGCV 41
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 51-79 1.16e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 41.63  E-value: 1.16e-03
                          10        20
                  ....*....|....*....|....*....
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGfSVQVL 79
Cdd:COG0029     5 TDVLVIGSGIAGLSAALKLAERG-RVTLL 32
PLN02676 PLN02676
polyamine oxidase
 52-88 1.30e-03

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 41.24  E-value: 1.30e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFS-VQVLEARNRVGGR 88
Cdd:PLN02676   28 SVIIVGAGMSGISAAKTLSEAGIEdILILEATDRIGGR 65
HI0933_like pfam03486
HI0933-like protein;
51-86 1.49e-03

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 41.03  E-value: 1.49e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVG 86
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLG 36
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 51-84 1.58e-03

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 40.77  E-value: 1.58e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEARNR 84
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLLARAGVRVVLVERHAT 35
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
54-86 1.85e-03

Predicted flavoprotein YhiN [General function prediction only];


Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 40.80  E-value: 1.85e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1071014626  54 LVLGAGIAGLVTALELSRAGFSVQVLEARNRVG 86
Cdd:COG2081     1 IVIGAGAAGLMAAITAAERGARVLLLEKNPKVG 33
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
52-91 2.78e-03

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 40.10  E-value: 2.78e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAgFSVQVLEARNRVGGRTWT 91
Cdd:COG2907     5 RIAVIGSGISGLTAAWLLSRR-HDVTLFEANDRLGGHTHT 43
PRK13984 PRK13984
putative oxidoreductase; Provisional
 49-87 2.83e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 40.52  E-value: 2.83e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1071014626  49 QGTRVLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGG 87
Cdd:PRK13984  282 KNKKVAIVGSGPAGLSAAYFLATMGYEVTVYESLSKPGG 320
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 53-89 3.10e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 39.96  E-value: 3.10e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1071014626  53 VLVLGAGIAGLVTALELSRAGFSVQVLEARNRVGGRT 89
Cdd:pfam00890   2 VLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGAT 38
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
51-105 3.91e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 39.50  E-value: 3.91e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVqVLEARnrvggrtwtlrngdRVDYKDGRT 105
Cdd:PRK07494    8 TDIAVIGGGPAGLAAAIALARAGASV-ALVAP--------------EPPYADLRT 47
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
53-86 5.53e-03

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 39.36  E-value: 5.53e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1071014626  53 VLVLGAGIAGLVTALELSRA-GFSVQVLEARNRVG 86
Cdd:COG0579     7 VVIIGAGIVGLALARELSRYeDLKVLVLEKEDDVA 41
PRK06185 PRK06185
FAD-dependent oxidoreductase;
51-81 8.81e-03

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 38.69  E-value: 8.81e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1071014626  51 TRVLVLGAGIAGLVTALELSRAGFSVQVLEA 81
Cdd:PRK06185    7 TDCCIVGGGPAGMMLGLLLARAGVDVTVLEK 37
PRK06753 PRK06753
hypothetical protein; Provisional
 52-85 9.66e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 38.52  E-value: 9.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1071014626  52 RVLVLGAGIAGLVTALELSRAGFSVQVLEARNRV 85
Cdd:PRK06753    2 KIAIIGAGIGGLTAAALLQEQGHEVKVFEKNESV 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH