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Conserved domains on  [gi|1092687888|ref|WP_070620626|]
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MULTISPECIES: PTS sugar transporter subunit IIC [unclassified Aerococcus]

Protein Classification

PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC( domain architecture ID 10007905)

PTS mannose/fructose/sorbose/N-acetylgalactosamine-specific transporter subunit IIC is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates (such as mannose, fructose, sorbose, and N-acetylgalactosamine) concomitantly with their translocation across the cell membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 1-276 2.88e-70

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


:

Pssm-ID: 442929  Cd Length: 259  Bit Score: 218.45  E-value: 2.88e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888   1 MAIQWWQILLLTLYSGYQIWDELHLVTSAGSAVFAGLFTGLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDANSGTVL 80
Cdd:COG3715     1 MEISLIQAILIGLVAFLAGIDGLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVVNIGGAVPPDPALAGII 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  81 ATAFSVAIGMEPEQaVAALAVPVAALMIQTDVLARFANTYFAHRIDSAIEKHDYKGIERNYLMGILPWALSRMIPIFLAL 160
Cdd:COG3715    81 GTALAILSGQDPET-AIALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFLLRAIPVFLAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 161 AFGGGVVQTAVDYLNtnlAWLADGLTLAGRVLPAVGFAILLRYLPVKKNIAYLALGFVITALLStvfsnitaisgelgkl 240
Cdd:COG3715   160 YFGADAVQALLNAIP---AWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLK---------------- 220

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1092687888 241 aeelsgtfvpLPMLGVSLIGFALAFIHYKNTVERQA 276
Cdd:COG3715   221 ----------LPLLAIAIIGVAIALIYYQLKKKKNA 246
 
Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 1-276 2.88e-70

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 442929  Cd Length: 259  Bit Score: 218.45  E-value: 2.88e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888   1 MAIQWWQILLLTLYSGYQIWDELHLVTSAGSAVFAGLFTGLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDANSGTVL 80
Cdd:COG3715     1 MEISLIQAILIGLVAFLAGIDGLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVVNIGGAVPPDPALAGII 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  81 ATAFSVAIGMEPEQaVAALAVPVAALMIQTDVLARFANTYFAHRIDSAIEKHDYKGIERNYLMGILPWALSRMIPIFLAL 160
Cdd:COG3715    81 GTALAILSGQDPET-AIALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFLLRAIPVFLAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 161 AFGGGVVQTAVDYLNtnlAWLADGLTLAGRVLPAVGFAILLRYLPVKKNIAYLALGFVITALLStvfsnitaisgelgkl 240
Cdd:COG3715   160 YFGADAVQALLNAIP---AWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLK---------------- 220

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1092687888 241 aeelsgtfvpLPMLGVSLIGFALAFIHYKNTVERQA 276
Cdd:COG3715   221 ----------LPLLAIAIIGVAIALIYYQLKKKKNA 246
EII-Sor pfam03609
PTS system sorbose-specific iic component;
5-266 1.97e-63

PTS system sorbose-specific iic component;


Pssm-ID: 460987  Cd Length: 233  Bit Score: 200.33  E-value: 1.97e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888   5 WWQILLLTLYSGYQIWDELHLVTSAGSAVFAGLFTGLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDANSGTVLATAF 84
Cdd:pfam03609   1 LIQAILIGLVAFLAGLDGLLGQFTLHRPLVAGTLVGLILGDVQTGLIIGATLQLMYLGVVTIGGAVPPDAALAGIIGTAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  85 SVAIGMEPEQaVAALAVPVAALMIQTDVLARFANTYFAHRIDSAIEKHDYKGIER-NYLMGILPWALSRMIPIFLALAFG 163
Cdd:pfam03609  81 AILSGIGPEA-AIALAVPVALLGQQLDNLVRTINSFFVHKADKYAEEGNYKGIERiHLLGPQLLGLLIRFIPVFLALYFG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 164 GGVVQTAVDYLNtnlAWLADGLTLAGRVLPAVGFAILLRYLPVKKNIAYLALGFVITALLStvfsnitaisgelgklaee 243
Cdd:pfam03609 160 ADAVQALLNAIP---EWLTNGLTVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLK------------------- 217

                         250       260
                  ....*....|....*....|...
gi 1092687888 244 lsgtfvpLPMLGVSLIGFALAFI 266
Cdd:pfam03609 218 -------LPLIAIAIIGVAIALI 233
PRK15065 PRK15065
mannose/fructose/sorbose family PTS transporter subunit IIC;
40-233 3.82e-15

mannose/fructose/sorbose family PTS transporter subunit IIC;


Pssm-ID: 237895  Cd Length: 262  Bit Score: 73.72  E-value: 3.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  40 GLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDAnsgtVLATAFSVAIGMEPEQAVAALAVPVAALMIQTDVLARFANT 119
Cdd:PRK15065   40 GLVLGDLKTGIILGGTLEMIALGWMNIGAAVAPDA----ALASVISAILVIAGHQGIGTGIAIAIPLAAAGQVLTIIVRT 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 120 ---YFAHRIDSAIEKHDYKGIERNYLMGILPWALSRMIP-IFLALAFGGGVVQTAvdyLNTNLAWLADGLTLAGRVLPAV 195
Cdd:PRK15065  116 itvAFQHAADKAAEEGNFRAIEWLHVSALLLQALRIAIPaALVALAVGTSAVQSM---LNAIPEVLTGGLNIGGGMIVVV 192

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1092687888 196 GFAILLRYLPVKKNIAYLALGFVITAllstvFSNITAI 233
Cdd:PRK15065  193 GYAMVINMMATRELMPFFYLGFVLAA-----FTNLNLI 225
 
Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 1-276 2.88e-70

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 442929  Cd Length: 259  Bit Score: 218.45  E-value: 2.88e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888   1 MAIQWWQILLLTLYSGYQIWDELHLVTSAGSAVFAGLFTGLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDANSGTVL 80
Cdd:COG3715     1 MEISLIQAILIGLVAFLAGIDGLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVVNIGGAVPPDPALAGII 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  81 ATAFSVAIGMEPEQaVAALAVPVAALMIQTDVLARFANTYFAHRIDSAIEKHDYKGIERNYLMGILPWALSRMIPIFLAL 160
Cdd:COG3715    81 GTALAILSGQDPET-AIALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFLLRAIPVFLAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 161 AFGGGVVQTAVDYLNtnlAWLADGLTLAGRVLPAVGFAILLRYLPVKKNIAYLALGFVITALLStvfsnitaisgelgkl 240
Cdd:COG3715   160 YFGADAVQALLNAIP---AWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLK---------------- 220

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1092687888 241 aeelsgtfvpLPMLGVSLIGFALAFIHYKNTVERQA 276
Cdd:COG3715   221 ----------LPLLAIAIIGVAIALIYYQLKKKKNA 246
EII-Sor pfam03609
PTS system sorbose-specific iic component;
5-266 1.97e-63

PTS system sorbose-specific iic component;


Pssm-ID: 460987  Cd Length: 233  Bit Score: 200.33  E-value: 1.97e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888   5 WWQILLLTLYSGYQIWDELHLVTSAGSAVFAGLFTGLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDANSGTVLATAF 84
Cdd:pfam03609   1 LIQAILIGLVAFLAGLDGLLGQFTLHRPLVAGTLVGLILGDVQTGLIIGATLQLMYLGVVTIGGAVPPDAALAGIIGTAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  85 SVAIGMEPEQaVAALAVPVAALMIQTDVLARFANTYFAHRIDSAIEKHDYKGIER-NYLMGILPWALSRMIPIFLALAFG 163
Cdd:pfam03609  81 AILSGIGPEA-AIALAVPVALLGQQLDNLVRTINSFFVHKADKYAEEGNYKGIERiHLLGPQLLGLLIRFIPVFLALYFG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 164 GGVVQTAVDYLNtnlAWLADGLTLAGRVLPAVGFAILLRYLPVKKNIAYLALGFVITALLStvfsnitaisgelgklaee 243
Cdd:pfam03609 160 ADAVQALLNAIP---EWLTNGLTVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLK------------------- 217

                         250       260
                  ....*....|....*....|...
gi 1092687888 244 lsgtfvpLPMLGVSLIGFALAFI 266
Cdd:pfam03609 218 -------LPLIAIAIIGVAIALI 233
PRK15065 PRK15065
mannose/fructose/sorbose family PTS transporter subunit IIC;
40-233 3.82e-15

mannose/fructose/sorbose family PTS transporter subunit IIC;


Pssm-ID: 237895  Cd Length: 262  Bit Score: 73.72  E-value: 3.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  40 GLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDAnsgtVLATAFSVAIGMEPEQAVAALAVPVAALMIQTDVLARFANT 119
Cdd:PRK15065   40 GLVLGDLKTGIILGGTLEMIALGWMNIGAAVAPDA----ALASVISAILVIAGHQGIGTGIAIAIPLAAAGQVLTIIVRT 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 120 ---YFAHRIDSAIEKHDYKGIERNYLMGILPWALSRMIP-IFLALAFGGGVVQTAvdyLNTNLAWLADGLTLAGRVLPAV 195
Cdd:PRK15065  116 itvAFQHAADKAAEEGNFRAIEWLHVSALLLQALRIAIPaALVALAVGTSAVQSM---LNAIPEVLTGGLNIGGGMIVVV 192

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1092687888 196 GFAILLRYLPVKKNIAYLALGFVITAllstvFSNITAI 233
Cdd:PRK15065  193 GYAMVINMMATRELMPFFYLGFVLAA-----FTNLNLI 225
PRK09757 PRK09757
PTS N-acetylgalactosamine transporter subunit IIC;
38-284 2.37e-10

PTS N-acetylgalactosamine transporter subunit IIC;


Pssm-ID: 236621  Cd Length: 267  Bit Score: 60.24  E-value: 2.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888  38 FTGLVMGDVKTGLIIGGAMQLTILGVGTFGGASRIDANSGTVLATAFSVAIGMEPEqaVAALAVPVAALMIQTDVLARF- 116
Cdd:PRK09757   39 LTGAILGDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAK--TAIGLGLPFSLLMQYVILFFYs 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 117 ANTYFAHRIDSAIEKHDYKGIERNYLMGILPWALSRMIPIFLALAFGGGVVQTAVdylNTNLAWLADGLTLAGRVLPAVG 196
Cdd:PRK09757  117 AFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCTYLAQGAMQALV---KAMPAWLTHGFEVAGGILPAVG 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092687888 197 FAILLRYLPVKKNIAYLALGFVITALLStvFSNitaisgelgklaeelsgtfvplpMLGVSLIGFALAFIHYKNTVERQA 276
Cdd:PRK09757  194 FGLLLRVMFKAQYIPYLIAGFLFVCYIQ--VSN-----------------------LLPVAVLGAGFAVYEFFNAKSRQQ 248


                  ....*...
gi 1092687888 277 LEDKLAKA 284
Cdd:PRK09757  249 AQPQPVAS 256
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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