|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
219-621 |
1.77e-96 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 314.93 E-value: 1.77e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 219 SWSPDSRRIITAFDSAEPRVWDAATGEEVLSLHGrERRWVSVVSWSPDGSRIITDDISGTTAhIWDATTGEELLSLRGHS 298
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLG-LAAAVASLAASPDGARLAAGAGDLTLL-LLDAAAGALLATLLGHT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 299 QWACALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWSPDGTRLSIGAKIGGNRVWDATTGEPRLTV 377
Cdd:COG2319 79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLtGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 378 DNGARELSEVVWSPDGTRLATSSYlSPRVLILDASTGDVVQALTAGEDDVNDIAWSPDGERILTGLGDDRAAIWDAARGE 457
Cdd:COG2319 159 TGHSGAVTSVAFSPDGKLLASGSD-DGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 458 RLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWDASTGEVIHTYTG--NWVRDVVWTQGGPRVVTGSADGAAHVWDV 535
Cdd:COG2319 238 LLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGhsGGVNSVAFSPDGKLLASGSDDGTVRLWDL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 536 ITSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSLAGHRFGVTDAQWSPDGTRILTGSEDGTVR 615
Cdd:COG2319 318 ATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVR 397
|
....*.
gi 1092733634 616 LWDATT 621
Cdd:COG2319 398 LWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
30-497 |
3.19e-94 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 308.76 E-value: 3.19e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 30 AWSPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWDATTGADLLTLGVGGSG 109
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 110 VGGAVaWSPDSTRILTSFDDASARIWDASSGQVVRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWDVTTGTELLRVg 189
Cdd:COG2319 81 VLSVA-FSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTL- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 190 pmafvgrgatmgpdgrpthVGPIEPMTSLSWSPDSRRIITAfdsaeprvwdaatgeevlslhgrerrwvsvvswSPDGsr 269
Cdd:COG2319 159 -------------------TGHSGAVTSVAFSPDGKLLASG---------------------------------SDDG-- 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 270 iitddisgtTAHIWDATTGEELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWS 348
Cdd:COG2319 185 ---------TVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLtGHSGSVRSVAFS 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 349 PDGTRLSIGAKIGGNRVWDATTGEPRLTVDNGARELSEVVWSPDGTRLATSSYlSPRVLILDASTGDVVQALTAGEDDVN 428
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSD-DGTVRLWDLATGKLLRTLTGHTGAVR 334
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1092733634 429 DIAWSPDGERILTGLGDDRAAIWDAARGERLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWDAST 497
Cdd:COG2319 335 SVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
279-635 |
6.30e-86 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 285.65 E-value: 6.30e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 279 TAHIWDATTGEELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWSPDGTRLSIG 357
Cdd:COG2319 17 ALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLlGHTAAVLSVAFSPDGRLLASA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 358 AKIGGNRVWDATTGEPRLTVDNGARELSEVVWSPDGTRLATSSYlSPRVLILDASTGDVVQALTAGEDDVNDIAWSPDGE 437
Cdd:COG2319 97 SADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSA-DGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGK 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 438 RILTGLGDDRAAIWDAARGERLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWDASTGEVIHTYTG--NWVRDVVWT 515
Cdd:COG2319 176 LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGhsGSVRSVAFS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 516 QGGPRVVTGSADGAAHVWDVITSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSLAGHRFGVTD 595
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRS 335
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1092733634 596 AQWSPDGTRILTGSEDGTVRLWDATTGEMTGLF---------LCFLPDG 635
Cdd:COG2319 336 VAFSPDGKTLASGSDDGTVRLWDLATGELLRTLtghtgavtsVAFSPDG 384
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
12-329 |
4.43e-83 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 277.95 E-value: 4.43e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 12 DPREVSLYAGHFDALWGVAWSPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRV 91
Cdd:COG2319 109 TGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRL 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 92 WDATTGADLLTLgVGGSGVGGAVAWSPDSTRILTSFDDASARIWDASSGQVVRTLSGHTEHLTAVSWSPDGTRVATASDD 171
Cdd:COG2319 189 WDLATGKLLRTL-TGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSAD 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 172 GTARVWDVTTGTELLRVGpmafvgrgatmgpdgrpthvGPIEPMTSLSWSPDSRRIITAFDSAEPRVWDAATGEEVLSLH 251
Cdd:COG2319 268 GTVRLWDLATGELLRTLT--------------------GHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1092733634 252 GrERRWVSVVSWSPDGSRIITDDISGtTAHIWDATTGEELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVWDATT 329
Cdd:COG2319 328 G-HTGAVRSVAFSPDGKTLASGSDDG-TVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
305-635 |
9.52e-75 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 254.45 E-value: 9.52e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 305 AWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWSPDGTRLSIGAKIGGNRVWDATTGEPRLTVDNGARE 383
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLlGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 384 LSEVVWSPDGTRLATSSYLsPRVLILDASTGDVVQALTAGEDDVNDIAWSPDGERILTGLGDDRAAIWDAARGERLLTLE 463
Cdd:COG2319 81 VLSVAFSPDGRLLASASAD-GTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 464 GHSDMITSVAWSPNGQRALTGSQDGTARIWDASTGEVIHTYTG--NWVRDVVWTQGGPRVVTGSADGAAHVWDVITSGEL 541
Cdd:COG2319 160 GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGhtGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 542 VTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSLAGHRFGVTDAQWSPDGTRILTGSEDGTVRLWDATT 621
Cdd:COG2319 240 RTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT 319
|
330 340
....*....|....*....|...
gi 1092733634 622 GEMTGLF---------LCFLPDG 635
Cdd:COG2319 320 GKLLRTLtghtgavrsVAFSPDG 342
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
294-618 |
6.86e-72 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 241.86 E-value: 6.86e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 294 LRGHSQWACALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWSPDGTRLSIGakiggnrvwdattge 372
Cdd:cd00200 5 LKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLkGHTGPVRDVAASADGTYLASG--------------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 373 prltvdngarelsevvwSPDGTrlatssylsprVLILDASTGDVVQALTAGEDDVNDIAWSPDGeRILTGLGDDR-AAIW 451
Cdd:cd00200 70 -----------------SSDKT-----------IRLWDLETGECVRTLTGHTSYVSSVAFSPDG-RILSSSSRDKtIKVW 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 452 DAARGERLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWDASTGEVIHTYTG--NWVRDVVWTQGGPRVVTGSADGA 529
Cdd:cd00200 121 DVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGhtGEVNSVAFSPDGEKLLSSSSDGT 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 530 AHVWDVITSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSLAGHRFGVTDAQWSPDGTRILTGS 609
Cdd:cd00200 201 IKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGS 280
|
....*....
gi 1092733634 610 EDGTVRLWD 618
Cdd:cd00200 281 ADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
21-326 |
1.37e-71 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 241.09 E-value: 1.37e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 21 GHFDALWGVAWSPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWDATTGADL 100
Cdd:cd00200 7 GHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 101 LTLgVGGSGVGGAVAWSPDSTRILTSFDDASARIWDASSGQVVRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWDVT 180
Cdd:cd00200 87 RTL-TGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLR 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 181 TGtELLRvgpmafvgrgatmgpdgrpTHVGPIEPMTSLSWSPDSRRIITAFDSAEPRVWDAATGEEVLSLHGRErRWVSV 260
Cdd:cd00200 166 TG-KCVA-------------------TLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHE-NGVNS 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1092733634 261 VSWSPDGSRIITDDISGTTaHIWDATTGEELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVWD 326
Cdd:cd00200 225 VAFSPDGYLLASGSEDGTI-RVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
57-367 |
1.98e-65 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 223.37 E-value: 1.98e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 57 ELFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWDATTGADLLTLgVGGSGVGGAVAWSPDSTRILTSFDDASARIWD 136
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTL-KGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 137 ASSGQVVRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWDVTTGTELlrvgpMAFVGrgatmgpdgrptHVGPIepmT 216
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCL-----TTLRG------------HTDWV---N 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 217 SLSWSPDSRRIITAFDSAEPRVWDAATGEEVLSLHGRErRWVSVVSWSPDGSRIIT--DDisgTTAHIWDATTGEELLSL 294
Cdd:cd00200 140 SVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHT-GEVNSVAFSPDGEKLLSssSD---GTIKLWDLSTGKCLGTL 215
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1092733634 295 RGHSQWACALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWSPDGTRLSIGAKIGGNRVWD 367
Cdd:cd00200 216 RGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLsGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
143-494 |
1.69e-62 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 214.89 E-value: 1.69e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 143 VRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWDVTTGTELLRVgpmafvgrgatmgpdgrpthVGPIEPMTSLSWSP 222
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTL--------------------KGHTGPVRDVAASA 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 223 DSRRIITAFDSAEPRVWDAATGEEVLSLHGRERrWVSVVSWSPDGsRIITDDISGTTAHIWDATTGEELLSLRGHSQWAC 302
Cdd:cd00200 62 DGTYLASGSSDKTIRLWDLETGECVRTLTGHTS-YVSSVAFSPDG-RILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVN 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 303 ALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL-GAGNSVETVSWSPDGTRLSIGakiggnrvwdattgeprltvdnga 381
Cdd:cd00200 140 SVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLtGHTGEVNSVAFSPDGEKLLSS------------------------ 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 382 relsevvwSPDGTrlatssylsprVLILDASTGDVVQALTAGEDDVNDIAWSPDGERILTGLGDDRAAIWDAARGERLLT 461
Cdd:cd00200 196 --------SSDGT-----------IKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQT 256
|
330 340 350
....*....|....*....|....*....|...
gi 1092733634 462 LEGHSDMITSVAWSPNGQRALTGSQDGTARIWD 494
Cdd:cd00200 257 LSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
417-656 |
2.12e-56 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 197.56 E-value: 2.12e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 417 VQALTAGEDDVNDIAWSPDGERILTGLGDDRAAIWDAARGERLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWDAS 496
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 497 TGEVIHTYTG--NWVRDVVWTQGGPRVVTGSADGAAHVWDVITSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRV 574
Cdd:cd00200 82 TGECVRTLTGhtSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 575 WDEVSGKIVLSLAGHRFGVTDAQWSPDGTRILTGSEDGTVRLWDATTGEMTGLF---------LCFLPDGGVAILDAPSL 645
Cdd:cd00200 162 WDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLrghengvnsVAFSPDGYLLASGSEDG 241
|
250
....*....|.
gi 1092733634 646 SLRsgpgeVWD 656
Cdd:cd00200 242 TIR-----VWD 247
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
461-681 |
1.40e-46 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 169.05 E-value: 1.40e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 461 TLEGHSDMITSVAWSPNGQRALTGSQDGTARIWDASTGEVIHTYTGN--WVRDVVWTQGGPRVVTGSADGAAHVWDVITS 538
Cdd:cd00200 4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHtgPVRDVAASADGTYLASGSSDKTIRLWDLETG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 539 GELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSLAGHRFGVTDAQWSPDGTRILTGSEDGTVRLWD 618
Cdd:cd00200 84 ECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWD 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1092733634 619 ATTG---------EMTGLFLCFLPDGGVAILDAPSLSLRsgpgeVWDylgrpeILAGQLTRVGVERRQYLNS 681
Cdd:cd00200 164 LRTGkcvatltghTGEVNSVAFSPDGEKLLSSSSDGTIK-----LWD------LSTGKCLGTLRGHENGVNS 224
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
10-178 |
2.34e-40 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 151.33 E-value: 2.34e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 10 TIDPREVSLYAGHFDALWGVAWSPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWSPDGTRLLTAAEDHSV 89
Cdd:cd00200 122 VETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTI 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 90 RVWDATTGADLLTLgVGGSGVGGAVAWSPDSTRILTSFDDASARIWDASSGQVVRTLSGHTEHLTAVSWSPDGTRVATAS 169
Cdd:cd00200 202 KLWDLSTGKCLGTL-RGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGS 280
|
....*....
gi 1092733634 170 DDGTARVWD 178
Cdd:cd00200 281 ADGTIRIWD 289
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
305-493 |
7.32e-17 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 84.63 E-value: 7.32e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 305 AWSPDSRRVATGSHDD---TVRVWDATTGQTQLVLGAGNSVETVSWSPDGTRLSIGAKIGGNR---VWDATTGEP-RLTV 377
Cdd:TIGR02800 196 AWSPDGQKLAYVSFESgkpEIYVQDLATGQREKVASFPGMNGAPAFSPDGSKLAVSLSKDGNPdiyVMDLDGKQLtRLTN 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 378 DNGARelSEVVWSPDGTRLA-TSSYL-SPRVLILDASTGDvVQALTAGEDDVNDIAWSPDGERILTGLGDD---RAAIWD 452
Cdd:TIGR02800 276 GPGID--TEPSWSPDGKSIAfTSDRGgSPQIYMMDADGGE-VRRLTFRGGYNASPSWSPDGDLIAFVHREGggfNIAVMD 352
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1092733634 453 AA-RGERLLTLEGHSDMITsvaWSPNGQRALTGSQDGTARIW 493
Cdd:TIGR02800 353 LDgGGERVLTDTGLDESPS---FAPNGRMILYATTRGGRGVL 391
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
134-518 |
6.52e-16 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 83.55 E-value: 6.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 134 IW--DASSGQVVRtLSGHTEHLTAVSWSPDGTRVA-TASDDGTARVW--DVTTGtELLRVgpmafvgrgatmgpdgrpTH 208
Cdd:COG4946 43 LWtvPADGGRARR-LTSHPGYESFPRFSPDGKWIAfTSDYDGNTDVYvmPAEGG-EPKRL------------------TY 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 209 vgpiEPMTS--LSWSPDSRRII-----TAFDSAEPRVW--DAATG-EEVLSLHgrerrWVSVVSWSPDGSRIITDDIS-- 276
Cdd:COG4946 103 ----HPANDrvVGWTPDGKSVLfasnrGSPPSRSNQLYtvPVDGGlPERLPLP-----PAGDGSFSPDGKKLAYTRIGre 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 277 ---------GTTAHIW--DATTGE--ELLSLRGHSQWACalaWSPD---------------SRRVATG------SHDD-- 320
Cdd:COG4946 174 frtwkryrgGTAGDIWiyDLGTGEftRLTDFGGNDRNPM---WIGDriyflsdrdgtfnlySYDPDGKdlrqltHFKDfd 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 321 -----------------TVRVWDATTGQTQLV---------------LGAGNSVETVSWSPDGTRLSIGAkiggnR---- 364
Cdd:COG4946 251 vrfpstdggrivyeqggDLYLLDLASGEPRKLnitlagdfpqrrprwVDVSGYLTSFALSPDGKRVAFEA-----Rgevf 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 365 ---VWDattGEPR-LTVDNGARElSEVVWSPDGTRLATSSYLS--PRVLILDASTGDVVQALTAGED-DVNDIAWSPDGE 437
Cdd:COG4946 326 tvpAEK---GPTRnLTNTPGVRE-RLPAWSPDGKSIAYFSDASgeYELYIAPADGSGEPKQLTLGDLgRVFNPVWSPDGK 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 438 RILtgLGDDRAAIW--DAARGE-RLLTLEGHSDMITSVAWSPNGqRALTGSQDGT-----ARIWDASTGEvIHTYTGNWV 509
Cdd:COG4946 402 KIA--FTDNRGRLWvvDLASGKvRKVDTDGYGDGISDLAWSPDS-KWLAYSKPGPnqlsqIFLYDVETGK-TVQLTDGRY 477
|
490
....*....|.
gi 1092733634 510 RD--VVWTQGG 518
Cdd:COG4946 478 DDgsPAFSPDG 488
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
238-455 |
2.37e-14 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 73.96 E-value: 2.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 238 VWDAATGEEVLSLHGRERRWVSVVSWSPDGSRIITDDISGTTAHIWDATTGEELLSLRGHSQWACALAWSPDSRRV-ATG 316
Cdd:COG3391 7 LLVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLyVAN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 317 SHDDTVRVWDATTGQTQLVLGAGNSVETVSWSPDGTRLSIgAKIGGNRVW--DATTGEPRLTVDNGaRELSEVVWSPDGT 394
Cdd:COG3391 87 SGSGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYV-ADSGNGRVSviDTATGKVVATIPVG-AGPHGIAVDPDGK 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1092733634 395 RLATSSYLSPR----VLILDASTGDVVQALTAGeDDVNDIAWSPDGERILTGLGDDRAAIWDAAR 455
Cdd:COG3391 165 RLYVANSGSNTvsviVSVIDTATGKVVATIPVG-GGPVGVAVSPDGRRLYVANRGSNTSNGGSNT 228
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
31-393 |
9.61e-13 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 73.15 E-value: 9.61e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 31 WSPDGTRL-LSGSHDGTARVW--DANRG--TELFALAGPSLsisAVAWSPDGTRLL--TAAEDHSVRVW-----DATTG- 97
Cdd:COG4946 68 FSPDGKWIaFTSDYDGNTDVYvmPAEGGepKRLTYHPANDR---VVGWTPDGKSVLfaSNRGSPPSRSNqlytvPVDGGl 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 98 ADLLTLGVGGSGVggavaWSPDSTRIL---TSFDDASAR---------IW--DASSGQVVRTLSGHTEHLTAVsWSPDgt 163
Cdd:COG4946 145 PERLPLPPAGDGS-----FSPDGKKLAytrIGREFRTWKryrggtagdIWiyDLGTGEFTRLTDFGGNDRNPM-WIGD-- 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 164 RVATASD-DGTARVWDVTT-GTELLRV-----GPMafvgRGATMGPDG-------------------------------- 204
Cdd:COG4946 217 RIYFLSDrDGTFNLYSYDPdGKDLRQLthfkdFDV----RFPSTDGGRivyeqggdlylldlasgeprklnitlagdfpq 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 205 -RPTHVGPIEPMTSLSWSPDSRRIitAFD--------SAEPRVWDAATGEEvlslHGRERRwvsvVSWSPDGSRII-TDD 274
Cdd:COG4946 293 rRPRWVDVSGYLTSFALSPDGKRV--AFEargevftvPAEKGPTRNLTNTP----GVRERL----PAWSPDGKSIAyFSD 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 275 ISGTTA-HIWDATTGEELLSLrGHSQWAC--ALAWSPDSRRVATGSHDDTVRVWDATTGQTQLVL--GAGNSVETVSWSP 349
Cdd:COG4946 363 ASGEYElYIAPADGSGEPKQL-TLGDLGRvfNPVWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDtdGYGDGISDLAWSP 441
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1092733634 350 DGTRLSIgAKIGGN-----RVWDATTGEPRLTVDNGARElSEVVWSPDG 393
Cdd:COG4946 442 DSKWLAY-SKPGPNqlsqiFLYDVETGKTVQLTDGRYDD-GSPAFSPDG 488
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
139-178 |
8.54e-12 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 60.79 E-value: 8.54e-12
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 139 SGQVVRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWD 178
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
207-625 |
1.51e-11 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 69.30 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 207 THVGPIepmTSLSWSPDSRRIitAFDSAE---PRVW--DAATGE-EVLSLHG-RERrwvsVVSWSPDGSRII----TDDI 275
Cdd:COG4946 58 SHPGYE---SFPRFSPDGKWI--AFTSDYdgnTDVYvmPAEGGEpKRLTYHPaNDR----VVGWTPDGKSVLfasnRGSP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 276 SGTTAHIW--DATTG-EELLSLrghsQWACALAWSPDSRRVATGSHDDTVRVWDATTGqtqlvlgagnsvetvswspdGT 352
Cdd:COG4946 129 PSRSNQLYtvPVDGGlPERLPL----PPAGDGSFSPDGKKLAYTRIGREFRTWKRYRG--------------------GT 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 353 RLSIgakiggnRVWDATTGEPRLTVDNGARELSeVVWSPDgtRLAtssYLSPR-----VLILDASTGDVVQaLTAGED-D 426
Cdd:COG4946 185 AGDI-------WIYDLGTGEFTRLTDFGGNDRN-PMWIGD--RIY---FLSDRdgtfnLYSYDPDGKDLRQ-LTHFKDfD 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 427 V-------NDIAWSPDGE----RILTG--------LGDDRaaiwdAARGERLLTLEGHsdmITSVAWSPNGQRALTgsqd 487
Cdd:COG4946 251 VrfpstdgGRIVYEQGGDlyllDLASGeprklnitLAGDF-----PQRRPRWVDVSGY---LTSFALSPDGKRVAF---- 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 488 gTARiwdastGEvIHTYT---GNWV----------RDVVWTQGGPRVVTGS-ADGAAHVW--DVITSGELVTL-RDDAAM 550
Cdd:COG4946 319 -EAR------GE-VFTVPaekGPTRnltntpgvreRLPAWSPDGKSIAYFSdASGEYELYiaPADGSGEPKQLtLGDLGR 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 551 VRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSL-AGHRFGVTDAQWSPDGtRILTGSEDGT-----VRLWDATTGEM 624
Cdd:COG4946 391 VFNPVWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDtDGYGDGISDLAWSPDS-KWLAYSKPGPnqlsqIFLYDVETGKT 469
|
.
gi 1092733634 625 T 625
Cdd:COG4946 470 V 470
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
683-1092 |
3.18e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 68.09 E-value: 3.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 683 PLPEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEASEPSEtgEAPEADALGEYAEVPSVFAVPAQQAAESAAEAEQPAG 762
Cdd:PRK07764 405 APAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPA--GNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAP 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 763 SQSPEDAPAQAQESSAPAS---DPLTEETPaETQAPQVEESVPapaEESEKTeIPAPVPTPEAEDPaaahQARHAAVTDH 839
Cdd:PRK07764 483 APPAAPAPAAAPAAPAAPAapaGADDAATL-RERWPEILAAVP---KRSRKT-WAILLPEATVLGV----RGDTLVLGFS 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 840 TPAEAEPVAAPTGETLLVQPFPVEQGL---VDGEVRP-PAEAQPTMVEMPHAPVVPEEerQAQPAPSPAETGEEADAEAG 915
Cdd:PRK07764 554 TGGLARRFASPGNAEVLVTALAEELGGdwqVEAVVGPaPGAAGGEGPPAPASSGPPEE--AARPAAPAAPAAPAAPAPAG 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 916 AdelavpAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAYEPVAIPAVEH 995
Cdd:PRK07764 632 A------AAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 996 AGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARAADPVDVPDAADAP 1075
Cdd:PRK07764 706 AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEM 785
|
410
....*....|....*..
gi 1092733634 1076 VSDAPPSSGAEAASAPT 1092
Cdd:PRK07764 786 AEDDAPSMDDEDRRDAE 802
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
456-494 |
4.91e-11 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 58.48 E-value: 4.91e-11
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 456 GERLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWD 494
Cdd:smart00320 2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
579-618 |
5.26e-11 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 58.48 E-value: 5.26e-11
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 579 SGKIVLSLAGHRFGVTDAQWSPDGTRILTGSEDGTVRLWD 618
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
120-390 |
6.33e-11 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 66.14 E-value: 6.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 120 STRI---LTSFDDASARIWDA-SSGQVVRTLSGHTEHLTAVSWSPDGTRVATAS-DDGTAR--VWDVTTGTELLRVGPma 192
Cdd:TIGR02800 155 STRIayvSKSGKSRRYELQVAdYDGANPQTITRSREPILSPAWSPDGQKLAYVSfESGKPEiyVQDLATGQREKVASF-- 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 193 fvgRGATMGPdgrpthvgpiepmtslSWSPDSRRIITAFDSA-EPRVWdaatgeeVLSLHGRERRWVSVV-------SWS 264
Cdd:TIGR02800 233 ---PGMNGAP----------------AFSPDGSKLAVSLSKDgNPDIY-------VMDLDGKQLTRLTNGpgidtepSWS 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 265 PDGSRII-TDDISGtTAHIW--DATTGE-ELLSLRGhsQWACALAWSPDSRRVATGSHDDT---VRVWDATTGQTQlVLG 337
Cdd:TIGR02800 287 PDGKSIAfTSDRGG-SPQIYmmDADGGEvRRLTFRG--GYNASPSWSPDGDLIAFVHREGGgfnIAVMDLDGGGER-VLT 362
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1092733634 338 AGNSVETVSWSPDGTRLSIGAKIGGNRVW--DATTG--EPRLTVDNGarELSEVVWS 390
Cdd:TIGR02800 363 DTGLDESPSFAPNGRMILYATTRGGRGVLglVSTDGrfRARLPLGNG--DVREPAWS 417
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
322-534 |
1.01e-10 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 63.56 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 322 VRVWDATTGQTQLVLGAGNSVETVSWSPDGTRLSIGAKIGGNRVWDATTGEPRLTVDNGARELSEVVWSPDGTRLATSSY 401
Cdd:COG3391 8 LVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 402 LSPRVLILDASTGDVVQALTAGeDDVNDIAWSPDGERIL-TGLGDDRAAIWDAARGERLLTLEGhSDMITSVAWSPNGQR 480
Cdd:COG3391 88 GSGRVSVIDLATGKVVATIPVG-GGPRGLAVDPDGGRLYvADSGNGRVSVIDTATGKVVATIPV-GAGPHGIAVDPDGKR 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1092733634 481 ALTGSQdGTARIW------DASTGEVIHTY-TGNWVRDVVWTQGGPRV-VTGSADGAAHVWD 534
Cdd:COG3391 166 LYVANS-GSNTVSvivsviDTATGKVVATIpVGGGPVGVAVSPDGRRLyVANRGSNTSNGGS 226
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
282-401 |
1.12e-10 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 61.23 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 282 IWDATTGEeLLSLRGHSQWACALAWSPDSRRVATGSHDDT---VRVWDATTGQTQLVLGAGNSVETVSWSPDGTRLSIGA 358
Cdd:COG0823 15 VVDLDGGE-PRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGgpqIYVVDADGGEPRRLTFGGGYNASPSWSPDGKRLAFVS 93
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1092733634 359 KIGGN---RVWDATTGEPRLTVDNGArelsEVVWSPDGTRLATSSY 401
Cdd:COG0823 94 RSDGRfdiYVLDLDGGAPRRLTDGPG----SPSWSPDGRRIVFSSD 135
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
456-494 |
1.42e-10 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 57.36 E-value: 1.42e-10
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 456 GERLLTLEGHSDMITSVAWSPNGQRALTGSQDGTARIWD 494
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
287-326 |
1.95e-10 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 56.94 E-value: 1.95e-10
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 287 TGEELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVWD 326
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
140-178 |
2.04e-10 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 56.97 E-value: 2.04e-10
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 140 GQVVRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWD 178
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
580-618 |
1.02e-09 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 55.04 E-value: 1.02e-09
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 580 GKIVLSLAGHRFGVTDAQWSPDGTRILTGSEDGTVRLWD 618
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
123-283 |
1.12e-09 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 58.53 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 123 ILTSFDDASARIW--DASSGQVVRtLSGHTEHLTAVSWSPDGTRVATASD-DGTARVWDV-TTGTELLRVgpmafvgrga 198
Cdd:COG0823 2 AFTLSRDGNSDIYvvDLDGGEPRR-LTNSPGIDTSPAWSPDGRRIAFTSDrGGGPQIYVVdADGGEPRRL---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 199 tmgpdgrpTHVGPIEpmTSLSWSPDSRRIitAFDSAEPRVWDAAtgeeVLSLHGRERRWVS----VVSWSPDGSRIITDD 274
Cdd:COG0823 71 --------TFGGGYN--ASPSWSPDGKRL--AFVSRSDGRFDIY----VLDLDGGAPRRLTdgpgSPSWSPDGRRIVFSS 134
|
....*....
gi 1092733634 275 ISGTTAHIW 283
Cdd:COG0823 135 DRGGRPDLY 143
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
191-414 |
1.41e-09 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 60.09 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 191 MAFVGRGATMGPDGRPTHVGPIEPMTSLSWSPDSRRIITAFDSAEPRVWDAATGEEVLSLHGRERRWVSVVSWSPDGSRI 270
Cdd:COG3391 3 VASSLLVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 271 ITDDISGTTAHIWDATTGEELLSLRGHSQWAcALAWSPDSRRV-ATGSHDDTVRVWDATTGQTQLVLGAGNSVETVSWSP 349
Cdd:COG3391 83 YVANSGSGRVSVIDLATGKVVATIPVGGGPR-GLAVDPDGGRLyVADSGNGRVSVIDTATGKVVATIPVGAGPHGIAVDP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1092733634 350 DGTRLsIGAKIGGNRVW------DATTGEPRLTVDNGARELSeVVWSPDGTRL-------ATSSYLSPRVLILDASTG 414
Cdd:COG3391 162 DGKRL-YVANSGSNTVSvivsviDTATGKVVATIPVGGGPVG-VAVSPDGRRLyvanrgsNTSNGGSNTVSVIDLATL 237
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
968-1144 |
4.09e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 61.02 E-value: 4.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 968 PASPTQVTQSSGTAESAYEPVAIPAVEHAGGEPVAAPTGETVAPDQLELPLTPAdTAGHEGQEATLDLSEEAPEAAAPVE 1047
Cdd:PRK07003 374 ARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPP-AAPAPPATADRGDDAADGDAPVPAK 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1048 ATAPPVADTAETARAADPVDVPDAADAPVSDAPPSSGAEAAS-----APTSSTPEGEPEDHAAQETPTEHAPVEPPqAQE 1122
Cdd:PRK07003 453 ANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPraaapSAATPAAVPDARAPAAASREDAPAAAAPP-APE 531
|
170 180
....*....|....*....|..
gi 1092733634 1123 NPERSPAlAEAEASQATDAEAA 1144
Cdd:PRK07003 532 ARPPTPA-AAAPAARAGGAAAA 552
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
288-326 |
4.84e-09 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 53.12 E-value: 4.84e-09
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 288 GEELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVWD 326
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
685-1146 |
6.00e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 60.38 E-value: 6.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 685 PEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEASEPSETG-EAPEADALGEYAEVPSVFAVPAQQAAESAAEAEQPAGS 763
Cdd:PRK07764 404 AAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPaGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPA 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 764 QSPEDAPAQAQESSAPAS---DPLTEETPaETQAPQVEESVPapaEESEKTeIPAPVPTPEAEDPAAAHQArhaaVTDHT 840
Cdd:PRK07764 484 PPAAPAPAAAPAAPAAPAapaGADDAATL-RERWPEILAAVP---KRSRKT-WAILLPEATVLGVRGDTLV----LGFST 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 841 PAEAEPVAAPTGETLLVQPFPVEQGL---VDGEVRP-PAEAQPTMVEMPHAPVVPEEerQAQPAPSPAETGEEADAEAGA 916
Cdd:PRK07764 555 GGLARRFASPGNAEVLVTALAEELGGdwqVEAVVGPaPGAAGGEGPPAPASSGPPEE--AARPAAPAAPAAPAAPAPAGA 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 917 delavpAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAYEPVAIPAVEHA 996
Cdd:PRK07764 633 ------AAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPA 706
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 997 GGEPVAAPTgetvapdqlelpltpadtaghegqeatldlseeapeaaapveatAPPVADTAETARAADPVDVPDAaDAPV 1076
Cdd:PRK07764 707 ATPPAGQAD--------------------------------------------DPAAQPPQAAQGASAPSPAADD-PVPL 741
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1077 SDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPERSPALAEAEASQATDAEAAAE 1146
Cdd:PRK07764 742 PPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAMELLEE 811
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
12-51 |
6.59e-09 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 52.70 E-value: 6.59e-09
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 12 DPREVSLYAGHFDALWGVAWSPDGTRLLSGSHDGTARVWD 51
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
521-655 |
1.14e-08 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 55.45 E-value: 1.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 521 VVTGSADGAAHVWDV-ITSGELVTLRDDAAMVRSYAWSPDGTKVL-AGFDDGVVRVWD-EVSGKIVLSLAGHRFGVTDAQ 597
Cdd:COG0823 2 AFTLSRDGNSDIYVVdLDGGEPRRLTNSPGIDTSPAWSPDGRRIAfTSDRGGGPQIYVvDADGGEPRRLTFGGGYNASPS 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1092733634 598 WSPDGTRIL-TGSEDGTVRLW--DATTGEMT-----GLFLCFLPDGGVAILdapsLSLRSGPGEVW 655
Cdd:COG0823 82 WSPDGKRLAfVSRSDGRFDIYvlDLDGGAPRrltdgPGSPSWSPDGRRIVF----SSDRGGRPDLY 143
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
762-1145 |
1.49e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 59.23 E-value: 1.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 762 GSQSPEDAPAQAQESSAPASDPLTEE--TPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEDPAAAHQARHAAVTDH 839
Cdd:PRK07764 400 SAAAAAPAAAPAPAAAAPAAAAAPAPaaAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAA 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 840 TPAEAEPVAAPTGETLLVQPFPVEQGLVDGEVrpPAEAQPTMVEM-------------PHAPVVPEEERQAQPA-PSPAE 905
Cdd:PRK07764 480 PAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT--LRERWPEILAAvpkrsrktwaillPEATVLGVRGDTLVLGfSTGGL 557
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 906 -----TGEEAD--AEAGADELAVpapEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSS 978
Cdd:PRK07764 558 arrfaSPGNAEvlVTALAEELGG---DWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAA 634
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 979 GTAESAYEPVAIPAVEHAGGEPVAAPTgetvapdqlelpltPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAE 1058
Cdd:PRK07764 635 APAEASAAPAPGVAAPEHHPKHVAVPD--------------ASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQ 700
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1059 TARAADPVDVPDAADAPVSdAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPERSPALAEAEASQA 1138
Cdd:PRK07764 701 PAPAPAATPPAGQADDPAA-QPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
|
....*..
gi 1092733634 1139 TDAEAAA 1145
Cdd:PRK07764 780 SEEEEMA 786
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
14-51 |
2.16e-08 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 51.19 E-value: 2.16e-08
10 20 30
....*....|....*....|....*....|....*...
gi 1092733634 14 REVSLYAGHFDALWGVAWSPDGTRLLSGSHDGTARVWD 51
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
116-261 |
2.61e-08 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 54.68 E-value: 2.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 116 WSPDSTRIL-TSFDDASARIW--DASSGQVVRtLSGHTEHLTAVSWSPDGTRVATASD-DGTARVWdvttgtellrvgpm 191
Cdd:COG0823 38 WSPDGRRIAfTSDRGGGPQIYvvDADGGEPRR-LTFGGGYNASPSWSPDGKRLAFVSRsDGRFDIY-------------- 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1092733634 192 afvgrgaTMGPDGRPTHV---GPIEPmtslSWSPDSRRII-TAFDSAEPRVWdaatgeeVLSLHGRERRWVSVV 261
Cdd:COG0823 103 -------VLDLDGGAPRRltdGPGSP----SWSPDGRRIVfSSDRGGRPDLY-------VVDLDGRKRRLTPAS 158
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
403-546 |
5.00e-08 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 53.52 E-value: 5.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 403 SPRVLILDASTGDVVQaLTAGEDDVNDIAWSPDGERIL-TGLGDDRAAIW--DAARGE-RLLTLEGHSDmiTSVAWSPNG 478
Cdd:COG0823 10 NSDIYVVDLDGGEPRR-LTNSPGIDTSPAWSPDGRRIAfTSDRGGGPQIYvvDADGGEpRRLTFGGGYN--ASPSWSPDG 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1092733634 479 QR-ALTGSQDGTARIW--DASTGEVIHTYTGNWvrDVVWTQGGPRVV-TGSADGAAHVWDVITSGELVTLRD 546
Cdd:COG0823 87 KRlAFVSRSDGRFDIYvlDLDGGAPRRLTDGPG--SPSWSPDGRRIVfSSDRGGRPDLYVVDLDGRKRRLTP 156
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
670-887 |
6.04e-08 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 57.36 E-value: 6.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 670 RVGVERRQ------YLNSDPLPEAVAEPSPAEAADE----DPTTQvpaeahqtpqtPEASEPSETGEAPEADALGEYAEV 739
Cdd:PRK10811 805 RVSGQRRRryrderYPTQSPMPLTVACASPEMASGKvwirYPVVR-----------PQDVQVEEQREAEEVQVQPVVAEV 873
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 740 PSVFAVPAQQAAESAAEAEQPAGSQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESekTEIPAPVpt 819
Cdd:PRK10811 874 PVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEV--AEHAEPV-- 949
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1092733634 820 pEAEDPAAAHQARHAAVTDHTPAEAEPVAAPTGETLLVQPFPVEQGLVDGEVRPPAEAQPTMVEMPHA 887
Cdd:PRK10811 950 -VEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHA 1016
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
765-1146 |
7.30e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 56.92 E-value: 7.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 765 SPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEDPAAAHQARHAAVTDHTPAEA 844
Cdd:PRK07764 388 AGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPA 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 845 EPVAAPTGETLLVQPFPVEQGLVDGEVRPPAEAQPTMVEMPHAPV----------VPEEERQAQPAPSPAETGEEAD--- 911
Cdd:PRK07764 468 PAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLrerwpeilaaVPKRSRKTWAILLPEATVLGVRgdt 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 912 --------------AEAGADELAVPAPEVELARTARRARHAAataqtpADAAPEQAAEDAAEAALPAESEPASPTQVTQS 977
Cdd:PRK07764 548 lvlgfstgglarrfASPGNAEVLVTALAEELGGDWQVEAVVG------PAPGAAGGEGPPAPASSGPPEEAARPAAPAAP 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 978 SGTAESAYEPVA-IPAVEHAGGEPVAAPTGETVAPDQLElplTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADT 1056
Cdd:PRK07764 622 AAPAAPAPAGAAaAPAEASAAPAPGVAAPEHHPKHVAVP---DASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1057 AETARAADPVDVPDAADAPVSdAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPERSPALAEAEAS 1136
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAA-QPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS 777
|
410
....*....|
gi 1092733634 1137 QATDAEAAAE 1146
Cdd:PRK07764 778 PPSEEEEMAE 787
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
55-93 |
1.12e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 49.23 E-value: 1.12e-07
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 55 GTELFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWD 93
Cdd:smart00320 2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
683-1120 |
1.15e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.87 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 683 PLPEAVAEPSPAEAADEDPTTQVPAEAHQT-PQTPEASEPSETGEAPEADAlgeyaevpsvfavpaqqaaesaaEAEQPA 761
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAARQAsPALPAAPAPPAVPAGPATPG-----------------------GPARPA 2758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 762 GSQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPaeeSEKTEIPAPVPTPEAEDPAAAHQARHAAvtdhTP 841
Cdd:PHA03247 2759 RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP---WDPADPPAAVLAPAAALPPAASPAGPLP----PP 2831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 842 AEAEPVAAPTGETLLVQPFPVEQGLVDG---EVRPPAEAQPTmveMPHAPVVPEEERQAQPAPSPAetgeeadaeagADE 918
Cdd:PHA03247 2832 TSAQPTAPPPPPGPPPPSLPLGGSVAPGgdvRRRPPSRSPAA---KPAAPARPPVRRLARPAVSRS-----------TES 2897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 919 LAVPAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPaSPTQVTQSSGTAESAYEPVAIPAVEHAGG 998
Cdd:PHA03247 2898 FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTT-DPAGAGEPSGAVPQPWLGALVPGRVAVPR 2976
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 999 EPVAAPTGETVAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARAADPVDVPDAADAPVSD 1078
Cdd:PHA03247 2977 FRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALD 3056
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1092733634 1079 A-PPSSGAEAASAPTSSTPEGEpedhaAQETPTEHAPVEPPQA 1120
Cdd:PHA03247 3057 PlPPEPHDPFAHEPDPATPEAG-----ARESPSSQFGPPPLSA 3094
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
766-925 |
2.66e-07 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 55.43 E-value: 2.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 766 PEDAPAQAQ-ESSAPASDPLTEETPAetqAPQVEESVPAPAEESEKTEIPAPVPTPEAEDPAAAHqarhaaVTDHTPaea 844
Cdd:PRK10811 850 PQDVQVEEQrEAEEVQVQPVVAEVPV---AAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVV------VETTHP--- 917
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 845 EPVAAPTGEtllvQPFPVEQGLVDGEVRPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELAVPAP 924
Cdd:PRK10811 918 EVIAAPVTE----QPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVET 993
|
.
gi 1092733634 925 E 925
Cdd:PRK10811 994 V 994
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
12-182 |
4.45e-07 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 52.39 E-value: 4.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 12 DPREVSLYAGHFDALWGVAWSPDGTRL-LSGSHDGTARVWDANRGTELFALAGPSlSISAVAWSPDGTRLL-TAAEDHSV 89
Cdd:COG3391 56 LLAGLGLGAAAVADADGADAGADGRRLyVANSGSGRVSVIDLATGKVVATIPVGG-GPRGLAVDPDGGRLYvADSGNGRV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 90 RVWDATTGADLLTLgvGGSGVGGAVAWSPDSTRILTSfDDASARIW------DASSGQVVRTLSGHtEHLTAVSWSPDGT 163
Cdd:COG3391 135 SVIDTATGKVVATI--PVGAGPHGIAVDPDGKRLYVA-NSGSNTVSvivsviDTATGKVVATIPVG-GGPVGVAVSPDGR 210
|
170 180
....*....|....*....|....*..
gi 1092733634 164 RV--------ATASDDGTARVWDVTTG 182
Cdd:COG3391 211 RLyvanrgsnTSNGGSNTVSVIDLATL 237
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
29-162 |
4.98e-07 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 54.27 E-value: 4.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 29 VAWSPDGTRLLSGSH-DGTARVW--DANRGTELFALAGPSLS-ISAVAWSPDGTRLLTAAEDHSVRVWDATTGADLLTLG 104
Cdd:COG4946 348 PAWSPDGKSIAYFSDaSGEYELYiaPADGSGEPKQLTLGDLGrVFNPVWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDT 427
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1092733634 105 VGGSGVGGAVAWSPDSTRILTSFDDASA----RIWDASSGQVVRtLSGHTEHLTAVSWSPDG 162
Cdd:COG4946 428 DGYGDGISDLAWSPDSKWLAYSKPGPNQlsqiFLYDVETGKTVQ-LTDGRYDDGSPAFSPDG 488
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
768-1163 |
6.00e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.56 E-value: 6.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 768 DAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPaeesekteiPAPVPTPEAEDPAAAHQARhaavtdhTPAEAEPV 847
Cdd:PHA03247 2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDP---------PPPSPSPAANEPDPHPPPT-------VPPPERPR 2653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 848 AAPTGETLLVQPFPVEQGLVDGEVRPPAEAQPTMVEMPHAPVV-----PEEERQAQPAPSPAETGEEADAEAGADELAVP 922
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTsladpPPPPPTPEPAPHALVSATPLPPGPAAARQASP 2733
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 923 A-------PEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPA-SPTQVTQSSGTAESAYEPVAIPAVE 994
Cdd:PHA03247 2734 AlpaapapPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAvASLSESRESLPSPWDPADPPAAVLA 2813
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 995 HAGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARA-ADPVDVPDAAD 1073
Cdd:PHA03247 2814 PAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPpVRRLARPAVSR 2893
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1074 APVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTehaPVEPPQAQENPERSPALAEAEASQATDAE------AAAEG 1147
Cdd:PHA03247 2894 STESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ---PPPPPPPRPQPPLAPTTDPAGAGEPSGAVpqpwlgALVPG 2970
|
410
....*....|....*.
gi 1092733634 1148 RPSAEEEPAEPAEPAE 1163
Cdd:PHA03247 2971 RVAVPRFRVPQPAPSR 2986
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
30-157 |
6.53e-07 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 50.44 E-value: 6.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 30 AWSPDGTRLL-SGSHDGTARVWDANR-GTELFALAGPSLSISAVAWSPDGTRLLTAAED---HSVRVWDATTGAD-LLTl 103
Cdd:COG0823 37 AWSPDGRRIAfTSDRGGGPQIYVVDAdGGEPRRLTFGGGYNASPSWSPDGKRLAFVSRSdgrFDIYVLDLDGGAPrRLT- 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1092733634 104 gvggsGVGGAVAWSPDSTRIL-TSFDDASARIWdassgqvVRTLSGHTEHLTAVS 157
Cdd:COG0823 116 -----DGPGSPSWSPDGRRIVfSSDRGGRPDLY-------VVDLDGRKRRLTPAS 158
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
30-256 |
8.08e-07 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 53.04 E-value: 8.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 30 AWSPDGTRLL-----SGSHdgTARVWDANRGTELFALAGPSLSIsAVAWSPDGTRLLTAA--EDHS-VRVWDATTGAdlL 101
Cdd:TIGR02800 196 AWSPDGQKLAyvsfeSGKP--EIYVQDLATGQREKVASFPGMNG-APAFSPDGSKLAVSLskDGNPdIYVMDLDGKQ--L 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 102 TLGVGGSGVGGAVAWSPDSTRIL-TSFDDASARIW--DASSGQVVRTLSGHTEHLTAvSWSPDGTRVATASDDGTAR--- 175
Cdd:TIGR02800 271 TRLTNGPGIDTEPSWSPDGKSIAfTSDRGGSPQIYmmDADGGEVRRLTFRGGYNASP-SWSPDGDLIAFVHREGGGFnia 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 176 VWDVTTG-TELLRVGPMafvgrgatmgpDGRPthvgpiepmtslSWSPDSRRIITAFDSAEPRVWdaatgeEVLSLHGRE 254
Cdd:TIGR02800 350 VMDLDGGgERVLTDTGL-----------DESP------------SFAPNGRMILYATTRGGRGVL------GLVSTDGRF 400
|
..
gi 1092733634 255 RR 256
Cdd:TIGR02800 401 RA 402
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
345-433 |
1.01e-06 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 48.04 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 345 VSWSPDGTRLSIGAKIG--------GNRVWDATTGEPrltvDNGARELSevvWSPDGTRLAtSSYLSPRVLILDASTGDV 416
Cdd:pfam12894 1 MSWCPTMDLIALATEDGelllhrlnWQRVWTLSPDKE----DLEVTSLA---WRPDGKLLA-VGYSDGTVRLLDAENGKI 72
|
90
....*....|....*..
gi 1092733634 417 VQALTAGEDDVNDIAWS 433
Cdd:pfam12894 73 VHHFSAGSDLITCLGWG 89
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1000-1146 |
1.03e-06 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 53.50 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1000 PVAAPTGETVAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARAADPVDV--PDAADAPVS 1077
Cdd:PRK10811 846 PVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETthPEVIAAPVT 925
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1092733634 1078 DAPP----SSGAEAASAPTSSTPEGEPEDHAAQETPTEHA----PVEPPQAQENPERSPALAEAEASQATDAEAAAE 1146
Cdd:PRK10811 926 EQPQviteSDVAVAQEVAEHAEPVVEPQDETADIEEAAETaevvVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVA 1002
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
55-93 |
1.10e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 46.18 E-value: 1.10e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 55 GTELFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWD 93
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| eIF2A |
pfam08662 |
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation ... |
387-509 |
1.90e-06 |
|
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation initiation factors.
Pssm-ID: 462552 [Multi-domain] Cd Length: 194 Bit Score: 49.96 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 387 VVWSPDGTRLAT-SSYLSPRVLILDAsTGDVVQALtaGEDDVNDIAWSPDGERILT-GLGDDRAAI--WDAARGERLLTL 462
Cdd:pfam08662 65 VAWSPNGKEFAViYGYMPAKVSFFDL-KGNVIHSF--GEQPRNTIFWSPFGRLVLLaGFGNLAGDIefWDVVNKKKIATA 141
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1092733634 463 EghSDMITSVAWSPNGQRALTGSQDGTARIwdaSTGEVIHTYTGNWV 509
Cdd:pfam08662 142 E--ASNATLCEWSPDGRYFLTATTAPRLRV---DNGFKIWHYNGALV 183
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
456-505 |
3.46e-06 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 46.50 E-value: 3.46e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1092733634 456 GERLLTL--EGHSDMITSVAWSPNGQRALTGSQDGTARIWDASTGEVIHTYT 505
Cdd:pfam12894 26 WQRVWTLspDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFS 77
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
681-924 |
6.67e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.09 E-value: 6.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 681 SDPLPEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEASEPsetgeaPEADALGEYAEVPSVFAVPAQQAAESAAEAEQP 760
Cdd:PHA03247 2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAP------PAAPAAGPPRRLTRPAVASLSESRESLPSPWDP 2804
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 761 AGSQSPEDAPAQAQessAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEDPAAAHQARHAAVTDHT 840
Cdd:PHA03247 2805 ADPPAAVLAPAAAL---PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARP 2881
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 841 PAEAEPVAAPTGETllvQPFPVEQGLVDGEVRPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELA 920
Cdd:PHA03247 2882 PVRRLARPAVSRST---ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA 2958
|
....
gi 1092733634 921 VPAP 924
Cdd:PHA03247 2959 VPQP 2962
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
968-1144 |
1.58e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 49.09 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 968 PASPTQVTQSSGTAESAYEPVAIPAVehagGEPVAAPTGETVAPDQLELPLTPADTAGhegqeatldLSEEAPEAAAPVE 1047
Cdd:PRK07994 368 PEVPPQSAAPAASAQATAAPTAAVAP----PQAPAVPPPPASAPQQAPAVPLPETTSQ---------LLAARQQLQRAQG 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1048 ATAPPVADTAETARAAdPVDVPDAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDhaaQETPTEHAPVEPPQAQEnPERS 1127
Cdd:PRK07994 435 ATKAKKSEPAAASRAR-PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVE---VKKEPVATPKALKKALE-HEKT 509
|
170
....*....|....*....
gi 1092733634 1128 PALAE--AEASQATDAEAA 1144
Cdd:PRK07994 510 PELAAklAAEAIERDPWAA 528
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
323-612 |
2.44e-05 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 48.42 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 323 RVWDATTGQTQLvLGAGNSVETVSWSPDGTRLSigakiggNRVWDATTGEPrltvdngarelseVVWSpdgTRLA---TS 399
Cdd:TIGR02800 109 RLYDVVSGQLQL-LGKQYTVTASQLRRVAHRIA-------DAIYEKLTGER-------------GAFS---TRIAyvsKS 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 400 SYLSPRVLILDASTGDVVQALTAGEDDVNDIAWSPDGERIL-TGLGDDRAAI--WDAARGERlLTLEGHSDMITSVAWSP 476
Cdd:TIGR02800 165 GKSRRYELQVADYDGANPQTITRSREPILSPAWSPDGQKLAyVSFESGKPEIyvQDLATGQR-EKVASFPGMNGAPAFSP 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 477 NGQR-ALTGSQDGTARIW--DASTGEV--IHTYTGN-----WVRD---VVWT---QGGPRVVTGSADGAahvwdvitSGE 540
Cdd:TIGR02800 244 DGSKlAVSLSKDGNPDIYvmDLDGKQLtrLTNGPGIdtepsWSPDgksIAFTsdrGGSPQIYMMDADGG--------EVR 315
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1092733634 541 LVTLRDDAAMvrSYAWSPDGTK-VLAGFDDGVVR--VWDEVSGKI-VLSLAGHrfgvtDAQ--WSPDGTRILTGSEDG 612
Cdd:TIGR02800 316 RLTFRGGYNA--SPSWSPDGDLiAFVHREGGGFNiaVMDLDGGGErVLTDTGL-----DESpsFAPNGRMILYATTRG 386
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
763-1138 |
2.55e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 49.00 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 763 SQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAP----VPTPEAEDPAAAHQARHAAVTD 838
Cdd:pfam03154 192 TQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPhpplQPMTQPPPPSQVSPQPLPQPSL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 839 HTPAEAEPVAAPTGETLL-----VQPFPVEQGLVDGEVRPPAEaqptmvemPHAPVvPEEERQAQPAPSPAETGEEADAE 913
Cdd:pfam03154 272 HGQMPPMPHSLQTGPSHMqhpvpPQPFPLTPQSSQSQVPPGPS--------PAAPG-QSQQRIHTPPSQSQLQSQQPPRE 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 914 AgadelavPAPEVELARTARRARHAAATAQTPADAA----PEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAYEPva 989
Cdd:pfam03154 343 Q-------PLPPAPLSMPHIKPPPTTPIPQLPNPQShkhpPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPP-- 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 990 iPAVEHAGGEPVAAPTGEtvAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARAADPVDVP 1069
Cdd:pfam03154 414 -PLQLMPQSQQLPPPPAQ--PPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMP 490
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1092733634 1070 DAAdaPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPvEPPQAQENPERSPALAEAEASQA 1138
Cdd:pfam03154 491 GIQ--PPSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESP-PPPPRSPSPEPTVVNTPSHASQS 556
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
971-1146 |
2.63e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 48.72 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 971 PTQVTQSSGTAESAYEPVAIPAVEHAGGEPVAAPTGETVAPdqlelPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATA 1050
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAA-----PAAAPAAAAAARAVAAAPARRSPAPEALAAARQA 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1051 PPVADTAETARAADPVDVPDAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVE------------PP 1118
Cdd:PRK12323 440 SARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEfaspapaqpdaaPA 519
|
170 180
....*....|....*....|....*...
gi 1092733634 1119 QAQENPERSPALAEAEASQATDAEAAAE 1146
Cdd:PRK12323 520 GWVAESIPDPATADPDDAFETLAPAPAA 547
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
497-534 |
2.71e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 42.30 E-value: 2.71e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 497 TGEVIHTYTG--NWVRDVVWTQGGPRVVTGSADGAAHVWD 534
Cdd:smart00320 1 SGELLKTLKGhtGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
71-183 |
3.83e-05 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 47.97 E-value: 3.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 71 VAWSP-DGTRLLTAAEDHSVRVWDATTG------ADLLTLGVGGSGVGGAVAWSPDSTRILTSFD-DASARIWDASSGQV 142
Cdd:PTZ00421 81 VAFNPfDPQKLFTASEDGTIMGWGIPEEgltqniSDPIVHLQGHTKKVGIVSFHPSAMNVLASAGaDMVVNVWDVERGKA 160
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1092733634 143 VRTLSGHTEHLTAVSWSPDGTRVATASDDGTARVWDVTTGT 183
Cdd:PTZ00421 161 VEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGT 201
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
286-445 |
4.09e-05 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 47.45 E-value: 4.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 286 TTGEELLSLRGhSQWACALawSPDSRRVA-----TGSHDDTVRVWDATTG---QTQLVLGAGNSVE-TVSWSPDGTRLS- 355
Cdd:PRK01029 221 PAGKKILALQG-NQLMPTF--SPRKKLLAfisdrYGNPDLFIQSFSLETGaigKPRRLLNEAFGTQgNPSFSPDGTRLVf 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 356 IGAKIGGNRVW----DATTGEPRLtVDNGARELSEVVWSPDGTRLATSSYLS--PRVLILDASTGDVVQaLTAGEDDVND 429
Cdd:PRK01029 298 VSNKDGRPRIYimqiDPEGQSPRL-LTKKYRNSSCPAWSPDGKKIAFCSVIKgvRQICVYDLATGRDYQ-LTTSPENKES 375
|
170
....*....|....*.
gi 1092733634 430 IAWSPDGERILTGLGD 445
Cdd:PRK01029 376 PSWAIDSLHLVYSAGN 391
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
58-279 |
5.59e-05 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 46.23 E-value: 5.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 58 LFALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWDATTGADLLTLGVGGSGVGGAVAWSPDSTRI-LTSFDDASARIWD 136
Cdd:COG3391 17 ALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLyVANSGSGRVSVID 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 137 ASSGQVVRTLSGHTeHLTAVSWSPDGTRV-ATASDDGTARVWDVTTGTELLRVGpmafVGRGATMgpdgrpthvgpiepm 215
Cdd:COG3391 97 LATGKVVATIPVGG-GPRGLAVDPDGGRLyVADSGNGRVSVIDTATGKVVATIP----VGAGPHG--------------- 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1092733634 216 tsLSWSPDSRRIITAfDSAEPRVW------DAATGEEVLSLHGRERrwVSVVSWSPDGSRI-ITDDISGTT 279
Cdd:COG3391 157 --IAVDPDGKRLYVA-NSGSNTVSvivsviDTATGKVVATIPVGGG--PVGVAVSPDGRRLyVANRGSNTS 222
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
683-1145 |
5.62e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.86 E-value: 5.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 683 PLPEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEASE-PSETGEAPEADALGEYAEVPSVFAVPAQQAAESAAEAEQPA 761
Cdd:PHA03307 22 PRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAaACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 762 GSQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEDPaAAHQARHAAVTDHTP 841
Cdd:PHA03307 102 REGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASD-AASSRQAALPLSSPE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 842 AEAEPVAAPTGetllvqPFPVEqglvdgevRPPAEAQPTmvemphAPVVPEEERQAQPAPSPaetgeeadaeAGADELAV 921
Cdd:PHA03307 181 ETARAPSSPPA------EPPPS--------TPPAAASPR------PPRRSSPISASASSPAP----------APGRSAAD 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 922 PAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAYEPVAIPAVEHAGGEPv 1001
Cdd:PHA03307 231 DAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAP- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1002 aaptgetvapdqlelplTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPvadTAETARAADPVDVPDAADAPvsdAPP 1081
Cdd:PHA03307 310 -----------------SSPRASSSSSSSRESSSSSTSSSSESSRGAAVSP---GPSPSRSPSPSRPPPPADPS---SPR 366
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1092733634 1082 SSGAEAASAPTSSTPEGEPEDHAAQEtptehAPVEPPQAQENPERSPALAEAEASQATDAEAAA 1145
Cdd:PHA03307 367 KRPRPSRAPSSPAASAGRPTRRRARA-----AVAGRARRRDATGRFPAGRPRPSPLDAGAASGA 425
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
413-452 |
5.73e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 41.53 E-value: 5.73e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 413 TGDVVQALTAGEDDVNDIAWSPDGERILTGLGDDRAAIWD 452
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
790-1012 |
7.41e-05 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 47.34 E-value: 7.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 790 AETQAPQVEESVPAPAEESEK--TEIPAPVPTPEAEDPAAAHQARHAAVTDHTPAEAEPVAAPTGETllVQPFPVEqglv 867
Cdd:PRK10811 848 VRPQDVQVEEQREAEEVQVQPvvAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVET--THPEVIA---- 921
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 868 dgevrPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELAVPAPEVElartarrarhaaataqtpad 947
Cdd:PRK10811 922 -----APVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVV-------------------- 976
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1092733634 948 aapeqaaedAAEAALPAESEPASPTQVTQSSGTAESAYEPVAIPAVEHAggepvAAPTGETVAPD 1012
Cdd:PRK10811 977 ---------AQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHA-----TAPMTRAPAPE 1027
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
416-477 |
8.04e-05 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 42.65 E-value: 8.04e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1092733634 416 VVQALTAGED-DVNDIAWSPDGERILTGLGDDRAAIWDAARGERLLTLEGHSDMITSVAWSPN 477
Cdd:pfam12894 29 VWTLSPDKEDlEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWGEN 91
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
789-1096 |
1.37e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 46.38 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 789 PAETQAPQVEESVPAPAeesekteiPAPVPTPEAEDPAAAHQARHAAVTDHTPAEAEPVAAPTGETLLVQPFPVEQGLVD 868
Cdd:PRK07003 368 PGGGVPARVAGAVPAPG--------ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 869 GEVRPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAeAGADELAVPAPevelartarrarhaaataqtPADa 948
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASD-APPDAAFEPAP--------------------RAA- 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 949 apeqaaedaaeaALPAESEPASPTQVTQSSGTAESAYEPVAIPAVEHAGGEPVAAptgetvapdqlelplTPADTAGheG 1028
Cdd:PRK07003 498 ------------APSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAA---------------APAARAG--G 548
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1092733634 1029 QEATLDL----------SEEAPEAAAPVEATAPPVADTAETARAADPVDVPDA-ADAPVSDAPPSSGAEAASAPTSSTP 1096
Cdd:PRK07003 549 AAAALDVlrnagmrvssDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRArAATGDAPPNGAARAEQAAESRGAPP 627
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
907-1145 |
1.57e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.02 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 907 GEEADAEAGADELAVPAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAYE 986
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 987 PVAIPAVEHAGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATL----DLSEEAPEAAAPVEATAPPVADTAETARA 1062
Cdd:PRK12323 450 PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPppweELPPEFASPAPAQPDAAPAGWVAESIPDP 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1063 ADPvdVPDAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPERSPALAEAEASQATDAE 1142
Cdd:PRK12323 530 ATA--DPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLPVRGLAQQLARQSELAGVE 607
|
...
gi 1092733634 1143 AAA 1145
Cdd:PRK12323 608 GDT 610
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
121-325 |
1.66e-04 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 46.23 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 121 TRILTSFDDASARIWDASSGQVVRTLSGHTEHLTAVSWSP-DGTRVATASDDGTARVWDVTTGTELLRVGPMAFVgrgat 199
Cdd:PLN00181 546 SQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTIKTKANI----- 620
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 200 mgpdgrpthvgpiepmTSLSWSPDSRRIItAFDSAEPRVWDAATGEEVLSL-----HGRERRWVSVVswspDGSRIITDD 274
Cdd:PLN00181 621 ----------------CCVQFPSESGRSL-AFGSADHKVYYYDLRNPKLPLctmigHSKTVSYVRFV----DSSTLVSSS 679
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1092733634 275 iSGTTAHIWDATTG------EELLSLRGHSQWACALAWSPDSRRVATGSHDDTVRVW 325
Cdd:PLN00181 680 -TDNTLKLWDLSMSisgineTPLHSFMGHTNVKNFVGLSVSDGYIATGSETNEVFVY 735
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
284-504 |
1.73e-04 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 44.70 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 284 DATTGEELLSLRGHSQWACALAWspDSRRVATGSHDDTVRVWDATTGQ---TQLVLGAGNSVETVS------WSPDGTRL 354
Cdd:pfam13360 9 DAATGAELWRVDLETGLGGGVAV--DGGRLFVATGGGQLVALDAATGKllwRQTLSGEVLGAPLVAggrvfvVAGDGSLI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 355 SIGAKIgGNRVWDATTGEPRLTVdngaRELSEVVWSPDGTRLATSsylSPRVLILDASTGDVV--QALTAGE-----DDV 427
Cdd:pfam13360 87 ALDAAD-GRRLWSYQRSGEPLAL----RSSGSPAVVGDTVVAGFS---SGKLVALDPATGKVRweAPLAAPRgtnelERL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1092733634 428 NDIAWSP--DGERILTGLGDDRAAIWDAARGERLLTLEGHSDMITSVAwspnGQRALTGSQDGTARIWDASTGEVIHTY 504
Cdd:pfam13360 159 VDITGTPvvAGGRVFASAYQGRLVAFDAATGRRLWTREISGPNGPILD----GDLLYVVSDDGELYALDRATGAVVWKT 233
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1068-1148 |
2.27e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 2.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1068 VPDAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPERSPALAEAEASQATDAEAAAEG 1147
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSA 464
|
.
gi 1092733634 1148 R 1148
Cdd:PRK07764 465 Q 465
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
670-868 |
2.40e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 45.63 E-value: 2.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 670 RVGVE----R------RQYLNSDPLPEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEASEPSETGEAPEADALGEYAEV 739
Cdd:PRK07994 346 RMGVEmtllRmlafhpAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAA 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 740 PSVFavpaqqaaesaaeaEQPAGSQSPEDAPAQAQESSAPASDPLtEETPAETQAPQVEESVPAPAEESEKTEIPAPVPT 819
Cdd:PRK07994 426 RQQL--------------QRAQGATKAKKSEPAAASRARPVNSAL-ERLASVRPAPSALEKAPAKKEAYRWKATNPVEVK 490
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1092733634 820 PEAEdpaaahqarhaavtdHTPAEAEPVAAPTGETLLVQPFPVEQGLVD 868
Cdd:PRK07994 491 KEPV---------------ATPKALKKALEHEKTPELAAKLAAEAIERD 524
|
|
| eIF2A |
pfam08662 |
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation ... |
469-583 |
2.59e-04 |
|
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation initiation factors.
Pssm-ID: 462552 [Multi-domain] Cd Length: 194 Bit Score: 43.42 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 469 ITSVAWSPNGQR--ALTGSQDGTARIWDAsTGEVIHTYTGNWVRDVVWTQGGPRVVT---GSADGAAHVWDVITSGELVT 543
Cdd:pfam08662 62 IHDVAWSPNGKEfaVIYGYMPAKVSFFDL-KGNVIHSFGEQPRNTIFWSPFGRLVLLagfGNLAGDIEFWDVVNKKKIAT 140
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1092733634 544 LrdDAAMVRSYAWSPDGTKVLAGFD------DGVVRVWdEVSGKIV 583
Cdd:pfam08662 141 A--EASNATLCEWSPDGRYFLTATTaprlrvDNGFKIW-HYNGALV 183
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
551-599 |
2.89e-04 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 41.11 E-value: 2.89e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1092733634 551 VRSYAWSPDGtKVLA-GFDDGVVRVWDEVSGKIVLSLAGHRFGVTDAQWS 599
Cdd:pfam12894 41 VTSLAWRPDG-KLLAvGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
763-924 |
3.02e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.23 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 763 SQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTeIPAPVPTPEAEDPAAAHQARHAAVTDHTPA 842
Cdd:PRK07003 394 SAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDA-ADGDAPVPAKANARASADSRCDERDAQPPA 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 843 EAEPVAAPTGETllvqpfpveqglvdgevRPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELAVP 922
Cdd:PRK07003 473 DSGSASAPASDA-----------------PPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPP 535
|
..
gi 1092733634 923 AP 924
Cdd:PRK07003 536 TP 537
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
498-534 |
3.99e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 39.25 E-value: 3.99e-04
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 498 GEVIHTYTG--NWVRDVVWTQGGPRVVTGSADGAAHVWD 534
Cdd:pfam00400 1 GKLLKTLEGhtGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
555-624 |
4.48e-04 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 40.34 E-value: 4.48e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1092733634 555 AWSPDGTKVLAGFDDGVVRVWdEVSGKIV--LSLAGHRFGVTDAQWSPDGTRILTGSEDGTVRLWDATTGEM 624
Cdd:pfam12894 2 SWCPTMDLIALATEDGELLLH-RLNWQRVwtLSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKI 72
|
|
| TALPID3 |
pfam15324 |
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ... |
792-925 |
5.87e-04 |
|
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.
Pssm-ID: 434634 [Multi-domain] Cd Length: 1288 Bit Score: 44.49 E-value: 5.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 792 TQAPQVEESVPAPAEESEkTEIPAPVPTPEAEDPAAAHQARHAAVTDHTPAEAEPVAAPtgetllvQPFPVEqglvdgEV 871
Cdd:pfam15324 964 QREPPVAASVPGDLPTKE-TLLPTPVPTPQPTPPCSPPSPLKEPSPVKTPDSSPCVSEH-------DFFPVK------EI 1029
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1092733634 872 RPPAEAQPtmveMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELAVPAPE 925
Cdd:pfam15324 1030 PPEKGADT----GPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPE 1079
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
459-618 |
6.08e-04 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 44.31 E-value: 6.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 459 LLTLEGHSDMiTSVAWSPNGQRALTGSQ-DGTARIWDASTGEVIHTYTGNWVRdvVWT----QGGPRVV-TGSADGAAHV 532
Cdd:PLN00181 526 VVELASRSKL-SGICWNSYIKSQVASSNfEGVVQVWDVARSQLVTEMKEHEKR--VWSidysSADPTLLaSGSDDGSVKL 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 533 WDVITSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVL-SLAGHRFGVTDAQWSpDGTRILTGSED 611
Cdd:PLN00181 603 WSINQGVSIGTIKTKANICCVQFPSESGRSLAFGSADHKVYYYDLRNPKLPLcTMIGHSKTVSYVRFV-DSSTLVSSSTD 681
|
....*..
gi 1092733634 612 GTVRLWD 618
Cdd:PLN00181 682 NTLKLWD 688
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
686-852 |
6.43e-04 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 43.81 E-value: 6.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 686 EAVAEPSPAEAADEDPTTQVPAE--AHQTPQTPEASEPSETGEAPEADALGEYAEvpsvfAVPAQQAAESAAEAEQPAGS 763
Cdd:PRK13108 280 EAPGALRGSEYVVDEALEREPAElaAAAVASAASAVGPVGPGEPNQPDDVAEAVK-----AEVAEVTDEVAAESVVQVAD 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 764 QSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEDPAAAHQARHAAVTDHTPAE 843
Cdd:PRK13108 355 RDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAV 434
|
....*....
gi 1092733634 844 AEPVAAPTG 852
Cdd:PRK13108 435 AGPGDDPAE 443
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
763-1147 |
6.60e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 44.29 E-value: 6.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 763 SQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPA-PAEESEKTEIPAPVPTPEaEDPAAAHQARHAAVTDHTP 841
Cdd:PHA03378 593 AQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMrPLRMQPITFNVLVFPTPH-QPPQVEITPYKPTWTQIGH 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 842 AEAEPVAAPTGETLLVQPFPveqglvdGEVRPPAEAqPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELAV 921
Cdd:PHA03378 672 IPYQPSPTGANTMLPIQWAP-------GTMQPPPRA-PTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGR 743
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 922 PAPEVELARTARRARHAAATAQTPAdaapeqaaedaaeaalpaeSEPASPTQVTQSSGTAESAYEPVAIPAVEHaggEPV 1001
Cdd:PHA03378 744 ARPPAAAPGRARPPAAAPGRARPPA-------------------AAPGAPTPQPPPQAPPAPQQRPRGAPTPQP---PPQ 801
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1002 AAPTGETVAPDQLELPLTPAD-------TAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARAA---DPVDVPDA 1071
Cdd:PHA03378 802 AGPTSMQLMPRAAPGQQGPTKqilrqllTGGVKRGRPSLKKPAALERQAAAGPTPSPGSGTSDKIVQAPvfyPPVLQPIQ 881
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1092733634 1072 ADAPVSDAPPSSGAEAASAPTSSTPEgepEDHAAQETPTEHAPVEPPQAQENPERSPALAEAEASQATDAEAAAEG 1147
Cdd:PHA03378 882 VMRQLGSVRAAAASTVTQAPTEYTGE---RRGVGPMHPTDIPPSKRAKTDAYVESQPPHGGQSHSFSVIWENVSQG 954
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
28-74 |
7.24e-04 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 39.95 E-value: 7.24e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1092733634 28 GVAWSPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWS 74
Cdd:pfam12894 43 SLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
683-791 |
7.46e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.93 E-value: 7.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 683 PLPEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEASEPSETGEAPEADALGEYAEVPSVFAVPAQQAAESAAEAEQPAG 762
Cdd:PRK14951 385 EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPV 464
|
90 100
....*....|....*....|....*....
gi 1092733634 763 SQSPEDAPAQAQESSAPASDPlTEETPAE 791
Cdd:PRK14951 465 RVAPEPAVASAAPAPAAAPAA-ARLTPTE 492
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
877-1079 |
7.77e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 43.71 E-value: 7.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 877 AQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGADELAVPAPEVELARTARRARHAAATAQTPADAAPEQAAED 956
Cdd:PRK12323 383 AQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAA 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 957 AAEAALPAESEPASPTQVTQSSGTAESAYEPVAIPAVEHAGGEPVAAptgetvAPDQLELPLTPADTAGHEGQEATLDLS 1036
Cdd:PRK12323 463 RPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASP------APAQPDAAPAGWVAESIPDPATADPDD 536
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1092733634 1037 EEAPEAAAPVEATAPPVADTAETARAADPVDVPDAADAPVSDA 1079
Cdd:PRK12323 537 AFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDG 579
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
61-271 |
8.06e-04 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 43.41 E-value: 8.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 61 LAGPSLSISAvAWSPDGTRLL-TAAED--HSVRVWDATTGAdlLTLGVGGSGVGGAVAWSPDSTRILTSFD-DASARIW- 135
Cdd:TIGR02800 186 TRSREPILSP-AWSPDGQKLAyVSFESgkPEIYVQDLATGQ--REKVASFPGMNGAPAFSPDGSKLAVSLSkDGNPDIYv 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 136 -DASSGQVVRtLSGHTEHLTAVSWSPDGTRVATASD-DGTARVWDV-TTGTELLRVgpmafVGRGATmgpdgrpthvgpi 212
Cdd:TIGR02800 263 mDLDGKQLTR-LTNGPGIDTEPSWSPDGKSIAFTSDrGGSPQIYMMdADGGEVRRL-----TFRGGY------------- 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1092733634 213 epMTSLSWSPDSRRIitAFDSAEPRVWDAAtgeeVLSLHGRERRWVSVV------SWSPDGSRII 271
Cdd:TIGR02800 324 --NASPSWSPDGDLI--AFVHREGGGFNIA----VMDLDGGGERVLTDTgldespSFAPNGRMIL 380
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
686-923 |
8.49e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.92 E-value: 8.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 686 EAVAEPSPAEAADEDPTTQV----PAEAHQTPQTPEASEP----------------SETGEAPEADALGEYAEVPSVFAV 745
Cdd:PRK10263 338 EPVTQTPPVASVDVPPAQPTvawqPVPGPQTGEPVIAPAPegypqqsqyaqpavqyNEPLQQPVQPQQPYYAPAAEQPAQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 746 PAQQAAESAAEAEQPAGSQSPEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPV--PTPEAE 823
Cdd:PRK10263 418 QPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVvePEPVVE 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 824 D--PAAAHQARHAAVTDHTPAEAEPVAAptgetlLVQPFPveqglvdGEVRPPAEAQPTmVEMPHAPVVPEEERQAQPAP 901
Cdd:PRK10263 498 EtkPARPPLYYFEEVEEKRAREREQLAA------WYQPIP-------EPVKEPEPIKSS-LKAPSVAAVPPVEAAAAVSP 563
|
250 260
....*....|....*....|..
gi 1092733634 902 SPAETGEEADAEAGADELAVPA 923
Cdd:PRK10263 564 LASGVKKATLATGAAATVAAPV 585
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
464-619 |
8.78e-04 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 43.34 E-value: 8.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 464 GHSDMITSVAWSP-NGQRALTGSQDGTARIWDASTgeviHTYTGNWVRDVVWTQGGPRVV--------------TGSADG 528
Cdd:PTZ00421 73 GQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIPE----EGLTQNISDPIVHLQGHTKKVgivsfhpsamnvlaSAGADM 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 529 AAHVWDVITSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWDEVSGKIVLSLAGHRFGVTD-AQWSPDGTRILT 607
Cdd:PTZ00421 149 VVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSQrCLWAKRKDLIIT 228
|
170
....*....|....*.
gi 1092733634 608 ----GSEDGTVRLWDA 619
Cdd:PTZ00421 229 lgcsKSQQRQIMLWDT 244
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
22-177 |
9.94e-04 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 43.54 E-value: 9.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 22 HFDALWGVAWSP-DGTRLLSGSHDGTARVWDANRGTELFALAGPSlSISAVAWSPDGTRLLT-AAEDHSVRVWDATTGAD 99
Cdd:PLN00181 574 HEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTIKTKA-NICCVQFPSESGRSLAfGSADHKVYYYDLRNPKL 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 100 LLTLGVGGSGVGGAVAWSpDSTRILTSFDDASARIWDAS---SG---QVVRTLSGHTEHLTAVSWSPDGTRVATASDDGT 173
Cdd:PLN00181 653 PLCTMIGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWDLSmsiSGineTPLHSFMGHTNVKNFVGLSVSDGYIATGSETNE 731
|
....
gi 1092733634 174 ARVW 177
Cdd:PLN00181 732 VFVY 735
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
569-626 |
1.17e-03 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 43.15 E-value: 1.17e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1092733634 569 DGVVRVWDEVSGKIVLSLAGHRFGVTDAQWSP-DGTRILTGSEDGTVRLWDATTGEMTG 626
Cdd:PLN00181 554 EGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIG 612
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
762-858 |
1.22e-03 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 41.91 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 762 GSQSPEDAPA--QAQESSAPASDPLT--------EETPAETQAPQVE-ESVPAPAEESEKTEIPAPVPTPEaedpaaahq 830
Cdd:PRK11633 64 PTQPPEGAAEavRAGDAAAPSLDPATvappntpvEPEPAPVEPPKPKpVEKPKPKPKPQQKVEAPPAPKPE--------- 134
|
90 100
....*....|....*....|....*...
gi 1092733634 831 arhaavtdhTPAEAEPVAAPTGETLLVQ 858
Cdd:PRK11633 135 ---------PKPVVEEKAAPTGKAYVVQ 153
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
541-576 |
1.26e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 37.71 E-value: 1.26e-03
10 20 30
....*....|....*....|....*....|....*.
gi 1092733634 541 LVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWD 576
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
537-576 |
1.47e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 37.68 E-value: 1.47e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1092733634 537 TSGELVTLRDDAAMVRSYAWSPDGTKVLAGFDDGVVRVWD 576
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
409-501 |
1.48e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 42.57 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 409 LDASTGDVVQALTAGEDDVNDIAWSPDGERILTGLGDDRAA-IWDAARGERLLTLEGHSDMITSVAWSPNGQRALTGSQD 487
Cdd:PTZ00421 110 LTQNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGADMVVnVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKD 189
|
90
....*....|....
gi 1092733634 488 GTARIWDASTGEVI 501
Cdd:PTZ00421 190 KKLNIIDPRDGTIV 203
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
26-195 |
1.65e-03 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 42.77 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 26 LWGVAW-SPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWSP-DGTRLLTAAEDHSVRVWDATTGADLLTL 103
Cdd:PLN00181 535 LSGICWnSYIKSQVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTI 614
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 104 GVGGSGVGGAvaWSPDSTRILtSFDDASARIW--DASSGQV-VRTLSGHTEHLTAVSWSpDGTRVATASDDGTARVWDVT 180
Cdd:PLN00181 615 KTKANICCVQ--FPSESGRSL-AFGSADHKVYyyDLRNPKLpLCTMIGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWDLS 690
|
170
....*....|....*.
gi 1092733634 181 TGTELLRVGPM-AFVG 195
Cdd:PLN00181 691 MSISGINETPLhSFMG 706
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
9-205 |
1.73e-03 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 41.60 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 9 ATIDPREVSLYAGHFDALWGVAWSPDGTRLLSGSHDGTARVWDANRGTELFALAGPSLSISAVAWSPDGTRL-LTAAEDH 87
Cdd:COG3391 11 VLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLyVANSGSG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 88 SVRVWDATTGADLLTLgvGGSGVGGAVAWSPDSTRIL-TSFDDASARIWDASSGQVVRTLSGHtEHLTAVSWSPDGTRVA 166
Cdd:COG3391 91 RVSVIDLATGKVVATI--PVGGGPRGLAVDPDGGRLYvADSGNGRVSVIDTATGKVVATIPVG-AGPHGIAVDPDGKRLY 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1092733634 167 TAS-DDGTA----RVWDVTTGTELLRVgPMAFVGRGATMGPDGR 205
Cdd:COG3391 168 VANsGSNTVsvivSVIDTATGKVVATI-PVGGGPVGVAVSPDGR 210
|
|
| PRK10819 |
PRK10819 |
transport protein TonB; Provisional |
789-904 |
1.75e-03 |
|
transport protein TonB; Provisional
Pssm-ID: 236768 [Multi-domain] Cd Length: 246 Bit Score: 41.59 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 789 PAETQAPQVEESVPAPAEESEkteiPAPVPTPEaedpaaahqarhaavtdhtPAEAEPVAAPTGETllvQPFPVeqglvd 868
Cdd:PRK10819 55 PADLEPPQAVQPPPEPVVEPE----PEPEPIPE-------------------PPKEAPVVIPKPEP---KPKPK------ 102
|
90 100 110
....*....|....*....|....*....|....*.
gi 1092733634 869 geVRPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPA 904
Cdd:PRK10819 103 --PKPKPKPVKKVEEQPKREVKPVEPRPASPFENTA 136
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
687-924 |
1.77e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.91 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 687 AVAEPSPAEAADEDPTTQVPAEAHQTP-QTPEASEPSETGEAPEADALGEYAEVPSVFAVPAQQAAESAAEAEQPAGSQS 765
Cdd:PRK07003 406 AGAALAPKAAAAAAATRAEAPPAAPAPpATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAP 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 766 PEDAPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEEsekteipapvPTPEAEDPaaahqarhaavtdhTPAEAE 845
Cdd:PRK07003 486 PDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAP----------PAPEARPP--------------TPAAAA 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 846 PVAAPTG-----ETLLVQPFPVEQG---LVDGEVRPPAEAQPTMVEMPHAPVVPEEERQAQPAPSPAETGEEADAEAGAD 917
Cdd:PRK07003 542 PAARAGGaaaalDVLRNAGMRVSSDrgaRAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAE 621
|
....*..
gi 1092733634 918 ELAVPAP 924
Cdd:PRK07003 622 SRGAPPP 628
|
|
| YvrE |
COG3386 |
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ... |
28-204 |
1.93e-03 |
|
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 442613 [Multi-domain] Cd Length: 266 Bit Score: 41.80 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 28 GVAWSPDGTRLLSGSHDGTARVWDANRG-TELFALagPSLSISAVAWSPDGtRLLTAAEDHSVRVWDATTGAdlltlgvg 106
Cdd:COG3386 12 GPVWDPDGRLYWVDIPGGRIHRYDPDGGaVEVFAE--PSGRPNGLAFDPDG-RLLVADHGRGLVRFDPADGE-------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 107 gsgvggAVAWSPDSTRILTSFDD----ASARIW------DASSGQVVR-TLSGHTEHLT-------AVSWSPDGTRV-AT 167
Cdd:COG3386 81 ------VTVLADEYGKPLNRPNDgvvdPDGRLYftdmgeYLPTGALYRvDPDGSLRVLAdgltfpnGIAFSPDGRTLyVA 154
|
170 180 190
....*....|....*....|....*....|....*..
gi 1092733634 168 ASDDGTARVWDVTTGTELLRVGPMAFVGRGATmGPDG 204
Cdd:COG3386 155 DTGAGRIYRFDLDADGTLGNRRVFADLPDGPG-GPDG 190
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
414-452 |
2.19e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.94 E-value: 2.19e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1092733634 414 GDVVQALTAGEDDVNDIAWSPDGERILTGLGDDRAAIWD 452
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
695-923 |
2.30e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 42.39 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 695 EAADEDPTTQVPAEAHQTP-QTPEASEPSETGEAPEADALGEYAEVPSVFAVPAQQAAESAAEAEQPAGSQSPEDA--PA 771
Cdd:PRK08691 388 ETAAKKPQPRPEAETAQTPvQTASAAAMPSEGKTAGPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAetPP 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 772 QAQESSAPASDPLTEETPAETqaPQVEESVPAPAEESEKTEIPApvptpeAEDPAAAHQARHAAVTDHTPAEAEPVAAPT 851
Cdd:PRK08691 468 ENQVSKNKAADNETDAPLSEV--PSENPIQATPNDEAVETETFA------HEAPAEPFYGYGFPDNDCPPEDGAEIPPPD 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 852 GETllVQPFPVEQGLVDGEVRPPAEAQPTMVEMPH--------APVVPEEERQAQPAPSPAETG--EEADAEAGADELAV 921
Cdd:PRK08691 540 WEH--AAPADTAGGGADEEAEAGGIGGNNTPSAPPpefstenwAAIVRHFARKLGAAQMPAQHSawTEYHPDTGLMVLAM 617
|
..
gi 1092733634 922 PA 923
Cdd:PRK08691 618 TA 619
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
990-1148 |
2.52e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.28 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 990 IPAVEHAGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVADTAETARAADPVDVP 1069
Cdd:PRK07764 378 LERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1070 DAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPERS-PALAEA--EASQATDAEAAAE 1146
Cdd:PRK07764 458 PAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwPEILAAvpKRSRKTWAILLPE 537
|
..
gi 1092733634 1147 GR 1148
Cdd:PRK07764 538 AT 539
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
1049-1134 |
2.77e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 42.18 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1049 TAPPVADTAETARAADPVDVPDAADAPVSDAPPSSGAEAASA---PTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPE 1125
Cdd:PRK12270 41 TAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAppkPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEVTPL 120
|
....*....
gi 1092733634 1126 RSPALAEAE 1134
Cdd:PRK12270 121 RGAAAAVAK 129
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
769-1143 |
3.07e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 769 APAQAQESSAPASDPlteETPAETQAPQVEESVPAPAEesekteiPAPVPTPEAEDPAAahqarhaavtdhTPAEAEPVA 848
Cdd:PRK07764 376 ARLERLERRLGVAGG---AGAPAAAAPSAAAAAPAAAP-------APAAAAPAAAAAPA------------PAAAPQPAP 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 849 APTGETllVQPFPVEQGLVDGEVRPPAEAQPTMVemPHAPVVPEEERQAQPAPSPAETGEEAdaeagadelavPAPEVEL 928
Cdd:PRK07764 434 APAPAP--APPSPAGNAPAGGAPSPPPAAAPSAQ--PAPAPAAAPEPTAAPAPAPPAAPAPA-----------AAPAAPA 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 929 ARTARRARHAAATAQT--PADAAPEQAAEDAAEAALPAESEPASP--TQVTQSSGTAESAY------------------- 985
Cdd:PRK07764 499 APAAPAGADDAATLRErwPEILAAVPKRSRKTWAILLPEATVLGVrgDTLVLGFSTGGLARrfaspgnaevlvtalaeel 578
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 986 -EPVAIPAVehAGGEPVAAPTGETVAPDQLELPLT---PADTAGHEGQEATL--DLSEEAPEAAAPVEATAPPVADTAET 1059
Cdd:PRK07764 579 gGDWQVEAV--VGPAPGAAGGEGPPAPASSGPPEEaarPAAPAAPAAPAAPApaGAAAAPAEASAAPAPGVAAPEHHPKH 656
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1060 ARAADPVDVPDAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEhAPVEPPQAQENPERSPALAEAEASQAT 1139
Cdd:PRK07764 657 VAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT-PPAGQADDPAAQPPQAAQGASAPSPAA 735
|
....
gi 1092733634 1140 DAEA 1143
Cdd:PRK07764 736 DDPV 739
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
897-1138 |
3.17e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.76 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 897 AQPAPSPAETGEEADAEAGADELAVPAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEP-ASPTQVT 975
Cdd:PRK07003 379 AVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPaKANARAS 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 976 QSSGTAESAYEPVAIPAVEHAGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATLDLSEEAPEAAAPVEATAPPVAD 1055
Cdd:PRK07003 459 ADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPA 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1056 TAETAR----AADPVDVPDAADAPVS-DAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHAPVEPPQAQENPErSPAL 1130
Cdd:PRK07003 539 AAAPAAraggAAAALDVLRNAGMRVSsDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGA-ARAE 617
|
....*...
gi 1092733634 1131 AEAEASQA 1138
Cdd:PRK07003 618 QAAESRGA 625
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
116-235 |
3.47e-03 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 41.29 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 116 WSPDSTRI-LTSFDDASARIWDAS---SGQVVRTLSGHTEHLTAVSWSPDGTRVATAS-DDGTARVW--DVTTGTEllrv 188
Cdd:PRK01029 288 FSPDGTRLvFVSNKDGRPRIYIMQidpEGQSPRLLTKKYRNSSCPAWSPDGKKIAFCSvIKGVRQICvyDLATGRD---- 363
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1092733634 189 gpmafvgRGATMGPDGRPthvGPiepmtslSWSPDSRRII-TAFDSAE 235
Cdd:PRK01029 364 -------YQLTTSPENKE---SP-------SWAIDSLHLVySAGNSNE 394
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
663-901 |
3.81e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 41.51 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 663 ILAGQLTRVGVERRQYLNSDPlpEAVAEPSPAEAADEDPTTQVPAEAHQTPQTPEAsePSETGEAPEADAlgEYAEVPSV 742
Cdd:PRK12727 28 ILSNRRTAEGIEIVAASNYDE--ELVQRALETARSDTPATAAAPAPAPQAPTKPAA--PVHAPLKLSANA--NMSQRQRV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 743 FAVPAQQAAESAAEAEQPAGSQSPEDAPAQAQESSAPASDPLTEETpAETQAPQVEESVPA-PAEESEKTEIPAPVPTPE 821
Cdd:PRK12727 102 ASAAEDMIAAMALRQPVSVPRQAPAAAPVRAASIPSPAAQALAHAA-AVRTAPRQEHALSAvPEQLFADFLTTAPVPRAP 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 822 AEDPAAAHQARHAAVTDHTPAEAEPvAAPTGETLLVQPFPVEQGLvdGEVRPPAeAQPTMVEMPHAPVVPEEERQAQPAP 901
Cdd:PRK12727 181 VQAPVVAAPAPVPAIAAALAAHAAY-AQDDDEQLDDDGFDLDDAL--PQILPPA-ALPPIVVAPAAPAALAAVAAAAPAP 256
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
116-159 |
4.91e-03 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 37.64 E-value: 4.91e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1092733634 116 WSPDSTRILTSFDDASARIWDASSGQVVRTLSGHTEHLTAVSWS 159
Cdd:pfam12894 46 WRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
133-185 |
5.16e-03 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 37.64 E-value: 5.16e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1092733634 133 RIWDASsgqvvrtLSGHTEHLTAVSWSPDGTRVATASDDGTARVWDVTTGTEL 185
Cdd:pfam12894 28 RVWTLS-------PDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIV 73
|
|
| eIF2A |
pfam08662 |
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation ... |
424-523 |
5.20e-03 |
|
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation initiation factors.
Pssm-ID: 462552 [Multi-domain] Cd Length: 194 Bit Score: 39.56 E-value: 5.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 424 EDDVNDIAWSPDGER--ILTGLGDDRAAIWDaARGERLLTLEGHSdmITSVAWSPNGQRALT---GSQDGTARIWDASTG 498
Cdd:pfam08662 59 EGPIHDVAWSPNGKEfaVIYGYMPAKVSFFD-LKGNVIHSFGEQP--RNTIFWSPFGRLVLLagfGNLAGDIEFWDVVNK 135
|
90 100
....*....|....*....|....*
gi 1092733634 499 EVIHTYTGNWVRDVVWTQGGPRVVT 523
Cdd:pfam08662 136 KKIATAEASNATLCEWSPDGRYFLT 160
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
767-1113 |
5.22e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 5.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 767 EDAPAQAQESSAPASDPLTEETPAETQAPQV-----------------EESVPAPAEESEKTEIPAPVPTPEAEDPAAAH 829
Cdd:PRK10811 686 EKRQAQQEAKALNVEEQSVQETEQEERVQQVqprrkqrqlnqkvrieqSVAEEAVAPVVEETVAAEPVVQEVPAPRTELV 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 830 QARHAAVTDHTPAEAEPVAAPTGEtllvqpfpvEQGLVDGEVRPPA--------------EAQPTMVEMP--HAPVVPEE 893
Cdd:PRK10811 766 KVPLPVVAQTAPEQDEENNAENRD---------NNGMPRRSRRSPRhlrvsgqrrrryrdERYPTQSPMPltVACASPEM 836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 894 E------RQAQPAPSPAETGEEADAEAGADELAVPAPEVelartarrarhaaataqtpadaapeqaaedaaeaalpaese 967
Cdd:PRK10811 837 AsgkvwiRYPVVRPQDVQVEEQREAEEVQVQPVVAEVPV----------------------------------------- 875
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 968 pASPTQVTQSSGTAESAYEPVAIPAVEHAGgEPVAAPTGETVAPDQLElplTPADTAGHEGQEATLDLSEEAPEAAAPVE 1047
Cdd:PRK10811 876 -AAAVEPVVSAPVVEAVAEVVEEPVVVAEP-QPEEVVVVETTHPEVIA---APVTEQPQVITESDVAVAQEVAEHAEPVV 950
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1092733634 1048 ATAPPVADTAETARAADPVDVPDAADAPVSDAPPSSGAEAASAPTSSTPEGEPEDHAAQETPTEHA 1113
Cdd:PRK10811 951 EPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHA 1016
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
777-1088 |
5.31e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 5.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 777 SAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEDpaaahqarhaAVTDHTPAEAEPVA-----AP- 850
Cdd:PRK10811 733 QSVAEEAVAPVVEETVAAEPVVQEVPAPRTELVKVPLPVVAQTAPEQD----------EENNAENRDNNGMPrrsrrSPr 802
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 851 ----TGE---------TLLVQPFPVEQglvdgevrppAEAQPTM------VEMPHAPV--VPEEERQAQPAPSPAETGEE 909
Cdd:PRK10811 803 hlrvSGQrrrryrderYPTQSPMPLTV----------ACASPEMasgkvwIRYPVVRPqdVQVEEQREAEEVQVQPVVAE 872
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 910 ADAEAGADElAVPAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAyEPVA 989
Cdd:PRK10811 873 VPVAAAVEP-VVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHA-EPVV 950
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 990 iPAVEHAGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATldlseeapeaaapveaTAPPVADTAETARAADPVDVP 1069
Cdd:PRK10811 951 -EPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVE----------------TVTAVEPEVAPAQVPEATVEH 1013
|
330 340
....*....|....*....|
gi 1092733634 1070 DAADAPVSDAP-PSSGAEAA 1088
Cdd:PRK10811 1014 NHATAPMTRAPaPEYVPEAP 1033
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
1051-1136 |
5.48e-03 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 40.87 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1051 PPVADTAETARAADPVDVPDAADAPVSD---APPSSGAEA---ASAPTSST-----PEGEPEDHAAQETPTEHAPVEPPQ 1119
Cdd:PHA03269 42 PAPAPHQAASRAPDPAVAPTSAASRKPDlaqAPTPAASEKfdpAPAPHQAAsrapdPAVAPQLAAAPKPDAAEAFTSAAQ 121
|
90
....*....|....*..
gi 1092733634 1120 AQENPERSPALAEAEAS 1136
Cdd:PHA03269 122 AHEAPADAGTSAASKKP 138
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
692-915 |
5.67e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 40.85 E-value: 5.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 692 SPAEAADEDPTTQVPAEAHQTPQTPEASEPSETGEA---PEADALGEYAEVPSVFAVPAQQAAESaaeaeqPAGSQSPED 768
Cdd:PRK08691 359 APLAAASCDANAVIENTELQSPSAQTAEKETAAKKPqprPEAETAQTPVQTASAAAMPSEGKTAG------PVSNQENND 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 769 APAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAEESEKTEIPAPVPTPEAEdpaaahqarhaavtdhTPAEAEPVA 848
Cdd:PRK08691 433 VPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSE----------------VPSENPIQA 496
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1092733634 849 APTGETLLVQPFPVEqglvdgevrPPAEAQPTMvEMPHAPVVPEEERQAQPAP----SPAET---GEEADAEAG 915
Cdd:PRK08691 497 TPNDEAVETETFAHE---------APAEPFYGY-GFPDNDCPPEDGAEIPPPDwehaAPADTaggGADEEAEAG 560
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
48-97 |
5.74e-03 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 37.26 E-value: 5.74e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1092733634 48 RVWDAnrgtelfALAGPSLSISAVAWSPDGTRLLTAAEDHSVRVWDATTG 97
Cdd:pfam12894 28 RVWTL-------SPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENG 70
|
|
| PQQ_ABC_repeats |
TIGR03866 |
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ... |
365-563 |
6.10e-03 |
|
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.
Pssm-ID: 274824 [Multi-domain] Cd Length: 310 Bit Score: 40.41 E-value: 6.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 365 VWDATTGEPRLTVDNGARELSeVVWSPDGTRLATSSYLSPRVLILDASTGDVVQALTAGEDDvNDIAWSPDGERILTGLG 444
Cdd:TIGR03866 25 VIDTATLKVTRTFPVGQRPRG-ITFSKDGKLLYVCASDSDTIQVIDPATGEVLHTLPSGPDP-EQFALHPNGKILYIANE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 445 DD-RAAIWDAARGERLLTL------EGhsdmitsVAWSPNGQRALTGSQDGTARIW-DASTGEVIH-TYTGNWVRDVVWT 515
Cdd:TIGR03866 103 DDaLVTVIDIETRKVLAQIdvgvepEG-------MAVSPDGKIVVNTSETTNMAHWiDTATYEIVDnTLVDARPRFAEFT 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1092733634 516 QGGPRV-VTGSADGAAHVWDVITSGELVTLRDDAAMVRSYAWSPDGTKV 563
Cdd:TIGR03866 176 ADGKELwVSSEIGGTVTVIDVATRKVIKKITFAIPGVHPEKVQPVGIKL 224
|
|
| eIF2A |
pfam08662 |
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation ... |
556-607 |
7.44e-03 |
|
Eukaryotic translation initiation factor eIF2A; This is a family of eukaryotic translation initiation factors.
Pssm-ID: 462552 [Multi-domain] Cd Length: 194 Bit Score: 39.18 E-value: 7.44e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1092733634 556 WSPDGTKV-LAGFDD--GVVRVWDEVSGKIVLSLagHRFGVTDAQWSPDGTRILT 607
Cdd:pfam08662 108 WSPFGRLVlLAGFGNlaGDIEFWDVVNKKKIATA--EASNATLCEWSPDGRYFLT 160
|
|
| PRK06549 |
PRK06549 |
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated |
769-818 |
8.77e-03 |
|
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
Pssm-ID: 235826 [Multi-domain] Cd Length: 130 Bit Score: 37.87 E-value: 8.77e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1092733634 769 APAQAQESSAPASDPLTeetPAETQAPQVEESVPAPAEESEKTEIPAPVP 818
Cdd:PRK06549 23 APAQAAAPAQPASTPVP---VPTEASPQVEAQAPQPAAAAGADAMPSPMP 69
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
762-1159 |
9.12e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 9.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 762 GSQSPEDaPAQAQESSAPASDPLTEETPAETQAPQVEESVPAPAE-ESEKTEIPAPVPTPEAEDPaaahqarhaavtdhT 840
Cdd:PHA03247 2499 GGGGPPD-PDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIRGLEElASDDAGDPPPPLPPAAPPA--------------A 2563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 841 PAEAEPVAAPTgetllvqPFPVEQGLVDGEVRPPAEAQPTMvemPHAPVVPEEERQAQPAPS-----------PAETGEE 909
Cdd:PHA03247 2564 PDRSVPPPRPA-------PRPSEPAVTSRARRPDAPPQSAR---PRAPVDDRGDPRGPAPPSplppdthapdpPPPSPSP 2633
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 910 ADAEAGADELAvPAPEVELARTARRARHAAATAQTPADAAPEQAAEDAAEAALPAESEPASPTQVTQSSGTAESAYEP-- 987
Cdd:PHA03247 2634 AANEPDPHPPP-TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPap 2712
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 988 ------VAIPAVEHAGGEPVAAPTGETVAPDQLELPLTPADTAGHEGQEATL----DLSEEAPEAAAPVEATAPPVADTA 1057
Cdd:PHA03247 2713 halvsaTPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgppaPAPPAAPAAGPPRRLTRPAVASLS 2792
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1092733634 1058 ETARAA----DPVDVPDAADAPVSDAPPSSGAEAASA-PTSSTPEGEPEDHAAQET------------------PTEHAP 1114
Cdd:PHA03247 2793 ESRESLpspwDPADPPAAVLAPAAALPPAASPAGPLPpPTSAQPTAPPPPPGPPPPslplggsvapggdvrrrpPSRSPA 2872
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1092733634 1115 VEPPQAQENPERS---PALAEAEASQATDAEAAAEGRPSAEEEPAEPA 1159
Cdd:PHA03247 2873 AKPAAPARPPVRRlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ 2920
|
|
| |
