|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
18-827 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1461.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 18 GHQVRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIA 97
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 98 IYDTMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVP 177
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 178 QLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSI 257
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDI----TIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 258 RMRGVTSIEQEGTRQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRIVVKLKRDAVPRVVLNNLY 337
Cdd:PRK05560 238 VMRAKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 338 KHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSA 417
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 418 TVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGD 497
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 498 DRRTQIVAAEGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCSTHDWILFFTN 577
Cdd:PRK05560 477 PRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTN 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 578 KGRVYRLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESARSAGLIAIN 657
Cdd:PRK05560 557 RGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 658 LREGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSMVVV-EEEHNLLVATTGGF 736
Cdd:PRK05560 637 LDEGDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVrEDSQEILTVTENGY 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 737 GKKTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVDNDDEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVE 816
Cdd:PRK05560 715 GKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDK 794
|
810
....*....|.
gi 1093454911 817 LLAIDRNVEDE 827
Cdd:PRK05560 795 VVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-820 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1365.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 1 MSDDNNNDgssfgsgvlghQVRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSA 80
Cdd:COG0188 1 MSDPPPAE-----------RIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 81 KPVSDTMGNYHPHGDIAIYDTMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQP 160
Cdd:COG0188 70 RVVGDVMGKYHPHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 161 NYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQI 240
Cdd:COG0188 150 NYDGSEQEPTVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDA----TIEELMEYIPGPDFPTGGII 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 241 VGDKGIKEAYTTGRGSIRMRGVTSIEQEGT-RQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRI 319
Cdd:COG0188 226 VGREGIREAYETGRGSIRVRAKAEIEELKRgREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESD-RDGMRI 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 320 VVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGL 399
Cdd:COG0188 305 VIELKRDANPEVVLNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 400 VKALDMLDEVIALIRRSATVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDR 479
Cdd:COG0188 385 LIALDNIDEVIAIIRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEER 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 480 QRAIVKEELTEVVEKYGDDRRTQIVAAEGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDI 559
Cdd:COG0188 465 LLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDF 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 560 VRHFFVCSTHDWILFFTNKGRVYRLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQDSPYLVLATSEGKVKK 639
Cdd:COG0188 545 VEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKK 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 640 SRLEDYESARSAGLIAINLREGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSM 719
Cdd:COG0188 625 TPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGM 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 720 VVVEEEHNLLVATTGGFGKKTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVDNDDEIFAVTSAGDIIRTNVNEIRAT 799
Cdd:COG0188 703 AVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVT 782
|
810 820
....*....|....*....|.
gi 1093454911 800 SRATKGVRLVNLADGVELLAI 820
Cdd:COG0188 783 GRNTQGVRLIRLDEGDKVVSV 803
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
136-829 |
0e+00 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 1298.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 136 TEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPD 215
Cdd:NF038098 538 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWCLDNPE 617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 216 ADEKTTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSIEQEGT-RQSIVITELPYQVNPDRMIANIAD 294
Cdd:NF038098 618 ADEEETLAAVMERVKGPDFPTHGLIVGTQGIEDAYRTGRGSIRMRGVVEVEEDARgRTSLVITELPYQVNPDNLIESIAE 697
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 295 QVKDGRLQGIASIDDESDLKWGMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQ 374
Cdd:NF038098 698 QVRDGKLAGISNIEDESSDRVGMRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRHYVDHQ 777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 375 IEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQ 454
Cdd:NF038098 778 LDVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASPTVDVARTGLIELLDVDEIQAQAILDMQLRRLAALERQ 857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 455 KIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGDDRRTQIVAAEGDVTEEDLIARENVVVTITSTGYAKRT 534
Cdd:NF038098 858 RIIDDLAKIEAEIADLEDILAKPERQRAIVRDELKEIVDKYGDDRRTRIIPADGDVSDEDLIAREDVVVTITETGYAKRT 937
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 535 KVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCSTHDWILFFTNKGRVYRLKAYELPEATRAARGQHVANLLEFQPEERIA 614
Cdd:NF038098 938 KTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDWILFFTNKGRVYRAKAYELPEASRTARGQHVANLLAFQPDERIA 1017
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 615 EVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESARSAGLIAINLREGDSLIGARLCSADDDLLLVSERGQAIRFTASDDA 694
Cdd:NF038098 1018 QVIQIKDYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRDGDELVGAVLCSAEDDLLLVSAKGQSIRFSATDEA 1097
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 695 LRPMGRATAGVQGMRFKGDDKLLSMVVVEEEHNLLVATTGGFGKKTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVD 774
Cdd:NF038098 1098 LRPMGRATSGVQGMRFNEDDELLSLNVVREGTYLLVATSGGYAKRTPIEEYPVQGRGGKGVLTIQYDRRRGRLVGALIVD 1177
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 1093454911 775 NDDEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVELLAIDRNVEDEGE 829
Cdd:NF038098 1178 DDDELYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNADEPDD 1232
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
21-825 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1196.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 21 VRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYD 100
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 101 TMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLL 180
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 181 MNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMR 260
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDI----SIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 261 GVTSIEQEGT-RQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRIVVKLKRDAVPRVVLNNLYKH 339
Cdd:TIGR01063 237 ARAEIEEDSKgREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESD-REGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 340 SQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATV 419
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 420 DTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGDDR 499
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 500 RTQIVAAEGDVTE-EDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCSTHDWILFFTNK 578
Cdd:TIGR01063 476 RTEIVYDESEDIDiEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 579 GRVYRLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESARSAGLIAINL 658
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 659 REGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSMVVVEEEHNLLVATTGGFGK 738
Cdd:TIGR01063 636 DDGDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 739 KTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVDNDDEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVELL 818
Cdd:TIGR01063 714 RTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLV 793
|
....*..
gi 1093454911 819 AIDRNVE 825
Cdd:TIGR01063 794 SVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
43-491 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 653.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 43 VGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMVRMAQPWSMRYPLVDGQGNF 122
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 123 GSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLRE 202
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 203 VADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSIEQEGTRQSIVITELPYQ 282
Cdd:cd00187 161 VIDALRALIDNPEA----SIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 283 VNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIV-DGVPRTL 361
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDESD-REGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 362 RIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSatvDTARTGLMGLL---DIDEIQAD 438
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1093454911 439 AILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEV 491
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
24-481 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 615.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 24 IDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMV 103
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 104 RMAQPWSMRYPLVDGQGNFGSRGD-DGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMN 182
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRLDgDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 183 GSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVgdkgikeayttGRGSIRMRGV 262
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDA----SIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 263 TSIEqegTRQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDLKWGMRIVVKLKRDAVPRVVLNNLYKHSQL 342
Cdd:smart00434 226 IEIE---DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 343 QTSFGANMLAIVD-GVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDE-KEKRAHILRGLVKALDMLDEVIALIRRSA-TV 419
Cdd:smart00434 303 QTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKlEAERLHILEGLFIALSIIDEIIVLIRSSKdLA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1093454911 420 DTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQR 481
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
45-488 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 606.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 45 RALPEIRDGLKPVHRRILYAMFdNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMVRMAQPWSMRYPLVDGQGNFGS 124
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMF-ELLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 125 R-GDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREV 203
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 204 ADAINWCLDNPDADEkttldaVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSIEQegtRQSIVITELPYQV 283
Cdd:pfam00521 160 IDALIALLDGPEATL------LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 284 NPDRMIANIADQVKDGRLQGIASIDDESDLkwGMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRI 363
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESDR--GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 364 DQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATVDTARTGLMGllDIDEIQADAILAM 443
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1093454911 444 QLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEEL 488
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
21-135 |
2.04e-73 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 262.35 E-value: 2.04e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 21 VRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYD 100
Cdd:NF038098 2 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYD 81
|
90 100 110
....*....|....*....|....*....|....*
gi 1093454911 101 TMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRY 135
Cdd:NF038098 82 TLVRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
18-827 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1461.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 18 GHQVRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIA 97
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 98 IYDTMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVP 177
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 178 QLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSI 257
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDI----TIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 258 RMRGVTSIEQEGTRQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRIVVKLKRDAVPRVVLNNLY 337
Cdd:PRK05560 238 VMRAKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 338 KHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSA 417
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 418 TVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGD 497
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 498 DRRTQIVAAEGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCSTHDWILFFTN 577
Cdd:PRK05560 477 PRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTN 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 578 KGRVYRLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESARSAGLIAIN 657
Cdd:PRK05560 557 RGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 658 LREGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSMVVV-EEEHNLLVATTGGF 736
Cdd:PRK05560 637 LDEGDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVrEDSQEILTVTENGY 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 737 GKKTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVDNDDEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVE 816
Cdd:PRK05560 715 GKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDK 794
|
810
....*....|.
gi 1093454911 817 LLAIDRNVEDE 827
Cdd:PRK05560 795 VVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-820 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1365.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 1 MSDDNNNDgssfgsgvlghQVRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSA 80
Cdd:COG0188 1 MSDPPPAE-----------RIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 81 KPVSDTMGNYHPHGDIAIYDTMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQP 160
Cdd:COG0188 70 RVVGDVMGKYHPHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 161 NYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQI 240
Cdd:COG0188 150 NYDGSEQEPTVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDA----TIEELMEYIPGPDFPTGGII 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 241 VGDKGIKEAYTTGRGSIRMRGVTSIEQEGT-RQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRI 319
Cdd:COG0188 226 VGREGIREAYETGRGSIRVRAKAEIEELKRgREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESD-RDGMRI 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 320 VVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGL 399
Cdd:COG0188 305 VIELKRDANPEVVLNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 400 VKALDMLDEVIALIRRSATVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDR 479
Cdd:COG0188 385 LIALDNIDEVIAIIRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEER 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 480 QRAIVKEELTEVVEKYGDDRRTQIVAAEGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDI 559
Cdd:COG0188 465 LLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDF 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 560 VRHFFVCSTHDWILFFTNKGRVYRLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQDSPYLVLATSEGKVKK 639
Cdd:COG0188 545 VEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKK 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 640 SRLEDYESARSAGLIAINLREGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSM 719
Cdd:COG0188 625 TPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGM 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 720 VVVEEEHNLLVATTGGFGKKTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVDNDDEIFAVTSAGDIIRTNVNEIRAT 799
Cdd:COG0188 703 AVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVT 782
|
810 820
....*....|....*....|.
gi 1093454911 800 SRATKGVRLVNLADGVELLAI 820
Cdd:COG0188 783 GRNTQGVRLIRLDEGDKVVSV 803
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
136-829 |
0e+00 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 1298.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 136 TEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPD 215
Cdd:NF038098 538 TEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWCLDNPE 617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 216 ADEKTTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSIEQEGT-RQSIVITELPYQVNPDRMIANIAD 294
Cdd:NF038098 618 ADEEETLAAVMERVKGPDFPTHGLIVGTQGIEDAYRTGRGSIRMRGVVEVEEDARgRTSLVITELPYQVNPDNLIESIAE 697
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 295 QVKDGRLQGIASIDDESDLKWGMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQ 374
Cdd:NF038098 698 QVRDGKLAGISNIEDESSDRVGMRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMIRHYVDHQ 777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 375 IEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQ 454
Cdd:NF038098 778 LDVIVRRTRYRLRKAEERAHILRGLVKALDALDEVIALIRASPTVDVARTGLIELLDVDEIQAQAILDMQLRRLAALERQ 857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 455 KIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGDDRRTQIVAAEGDVTEEDLIARENVVVTITSTGYAKRT 534
Cdd:NF038098 858 RIIDDLAKIEAEIADLEDILAKPERQRAIVRDELKEIVDKYGDDRRTRIIPADGDVSDEDLIAREDVVVTITETGYAKRT 937
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 535 KVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCSTHDWILFFTNKGRVYRLKAYELPEATRAARGQHVANLLEFQPEERIA 614
Cdd:NF038098 938 KTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDWILFFTNKGRVYRAKAYELPEASRTARGQHVANLLAFQPDERIA 1017
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 615 EVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESARSAGLIAINLREGDSLIGARLCSADDDLLLVSERGQAIRFTASDDA 694
Cdd:NF038098 1018 QVIQIKDYEDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAINLRDGDELVGAVLCSAEDDLLLVSAKGQSIRFSATDEA 1097
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 695 LRPMGRATAGVQGMRFKGDDKLLSMVVVEEEHNLLVATTGGFGKKTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVD 774
Cdd:NF038098 1098 LRPMGRATSGVQGMRFNEDDELLSLNVVREGTYLLVATSGGYAKRTPIEEYPVQGRGGKGVLTIQYDRRRGRLVGALIVD 1177
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 1093454911 775 NDDEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVELLAIDRNVEDEGE 829
Cdd:NF038098 1178 DDDELYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNADEPDD 1232
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
21-825 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1196.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 21 VRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYD 100
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 101 TMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLL 180
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 181 MNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMR 260
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDI----SIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 261 GVTSIEQEGT-RQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRIVVKLKRDAVPRVVLNNLYKH 339
Cdd:TIGR01063 237 ARAEIEEDSKgREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESD-REGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 340 SQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATV 419
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 420 DTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGDDR 499
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 500 RTQIVAAEGDVTE-EDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCSTHDWILFFTNK 578
Cdd:TIGR01063 476 RTEIVYDESEDIDiEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 579 GRVYRLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESARSAGLIAINL 658
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 659 REGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSMVVVEEEHNLLVATTGGFGK 738
Cdd:TIGR01063 636 DDGDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLLIVTENGYGK 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 739 KTKLSEYTPQNRGGMGVLTLKYDPKRGPLMGALVVDNDDEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVELL 818
Cdd:TIGR01063 714 RTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLV 793
|
....*..
gi 1093454911 819 AIDRNVE 825
Cdd:TIGR01063 794 SVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
18-759 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 877.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 18 GHQVRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIA 97
Cdd:PRK05561 7 LEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDSS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 98 IYDTMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVP 177
Cdd:PRK05561 87 IYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPARFP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 178 QLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDK-GIKEAYTTGRGS 256
Cdd:PRK05561 167 NLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDA----TLEELMEFVPGPDFPTGGEIITGRdGIRKAYETGRGS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 257 IRMRGVTSIEQ-EGTRQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDLKWGMRIVVKLKRDAV-PRVVLN 334
Cdd:PRK05561 243 IRVRARWEIEDlAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNRVdPEALMN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 335 NLYKHSQLQTSFGANMLAI-VDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALI 413
Cdd:PRK05561 323 HLFATTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRII 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 414 RRSatvDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVE 493
Cdd:PRK05561 403 RES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAK 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 494 KYGDDRRTQIVAAEGDV--TEEDLIARENVVVTITSTGYAKRTKVDAYKAQrrggkgvrGADLKQDDIVRHFFVCSTHDW 571
Cdd:PRK05561 480 KFGDPRRTPIEEAEEAIaiDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS--------GLSFKEGDSLLFAFEARTTDK 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 572 ILFFTNKGRVYRLKAYELPEatraAR--GQHVANLLEFQPEERIAEVLqiqSYQDSPYLVLATSEGKVKKSRLEDYESAR 649
Cdd:PRK05561 552 LLLFTSTGRVYSLPVHELPS----ARgdGEPLTGLVDLAPGEEIVHVL---AFDPDQKLLLASSAGYGFVVTLEDLVART 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 650 SAGLIAINLREGDSLIGARLCSADDDLLLVSERGQAIRFTASDdaLRPMGRAtAGVQGMRFKGDDKLLSMV-VVEEEHNL 728
Cdd:PRK05561 625 RAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSE--LPELGKG-KGVKLINLPKDDDGLVDLrVLNPEDGL 701
|
730 740 750
....*....|....*....|....*....|...
gi 1093454911 729 LVATTGGFGKKTKLSEYTPQ--NRGGMGVLTLK 759
Cdd:PRK05561 702 VLLTAGKRKLKLKPSELEKYrgKRARRGRLLPR 734
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
43-491 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 653.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 43 VGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMVRMAQPWSMRYPLVDGQGNF 122
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 123 GSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLRE 202
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 203 VADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSIEQEGTRQSIVITELPYQ 282
Cdd:cd00187 161 VIDALRALIDNPEA----SIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 283 VNPDRMIANIADQVKDGRLQGIASIDDESDlKWGMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIV-DGVPRTL 361
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDESD-REGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 362 RIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSatvDTARTGLMGLL---DIDEIQAD 438
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1093454911 439 AILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEV 491
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
24-481 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 615.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 24 IDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMV 103
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 104 RMAQPWSMRYPLVDGQGNFGSRGD-DGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMN 182
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRLDgDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 183 GSGGIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVgdkgikeayttGRGSIRMRGV 262
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDA----SIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 263 TSIEqegTRQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDLKWGMRIVVKLKRDAVPRVVLNNLYKHSQL 342
Cdd:smart00434 226 IEIE---DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 343 QTSFGANMLAIVD-GVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDE-KEKRAHILRGLVKALDMLDEVIALIRRSA-TV 419
Cdd:smart00434 303 QTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKlEAERLHILEGLFIALSIIDEIIVLIRSSKdLA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1093454911 420 DTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQR 481
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
45-488 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 606.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 45 RALPEIRDGLKPVHRRILYAMFdNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMVRMAQPWSMRYPLVDGQGNFGS 124
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMF-ELLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 125 R-GDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREV 203
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 204 ADAINWCLDNPDADEkttldaVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSIEQegtRQSIVITELPYQV 283
Cdd:pfam00521 160 IDALIALLDGPEATL------LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 284 NPDRMIANIADQVKDGRLQGIASIDDESDLkwGMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRI 363
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESDR--GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 364 DQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATVDTARTGLMGllDIDEIQADAILAM 443
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1093454911 444 QLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEEL 488
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
24-725 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 589.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 24 IDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMV 103
Cdd:PRK13979 16 IPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 104 RMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNG 183
Cdd:PRK13979 96 ILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 184 SGGIAVGMATNIPPHNLREVADAINWCLDNPDADEKTtldaVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVT 263
Cdd:PRK13979 176 AFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKE----LMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKT 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 264 SIEQ-EGTRQSIVITELPYQVNPDRMIANIADQVKDGR----LQGIASIDDESDlKWGMRIVVKLKRDA---VPRVVLNN 335
Cdd:PRK13979 252 KIEKlENGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESD-RNGIRAVIEFKKSAdedVAEKVLKY 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 336 LYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRR 415
Cdd:PRK13979 331 LYKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRS 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 416 SATVDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKY 495
Cdd:PRK13979 411 SKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKY 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 496 GDDRRTQIVA--AEGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKaqrRGGKGVRGADLKQDDIVRHFFVCSTHDWIL 573
Cdd:PRK13979 491 GDERRTSIIEddEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSYN---RSNSNVEDIEYREGDFNKFLIQSNTKDTLL 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 574 FFTNKGRVYRLKAYELPEATRAARGQHVANL-----LEfqpEERIAEVLQIQSYQDSPYLVLATSEGKVKKSRLEDYESA 648
Cdd:PRK13979 568 IFTDKGNMYQIKGINIPEFKWKEKGERLDEIikgidLE---SEKIIEAYSIEDFTPQKDFIFITDSGGIKKTSLDKFVTN 644
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1093454911 649 RSAgLIAINLREGDSLIGARL--CSADDDLLLVSERgQAIRFTASDDALRPMGRATAGVQGMRFKGDDKLLSMVVVEEE 725
Cdd:PRK13979 645 YTK-LMALKLKKGEKLIKVKLvdRTREEKFIKIKTK-KGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIKKVDFCDNY 721
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
26-762 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 579.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 26 INEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMVRM 105
Cdd:TIGR01061 6 LEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 106 AQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMNGSG 185
Cdd:TIGR01061 86 SQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 186 GIAVGMATNIPPHNLREVADAINWCLDNPDAdektTLDAVMERIKGPDFPTAAQIVGDKGIKEAYTTGRGSIRMRGVTSI 265
Cdd:TIGR01061 166 GIAAGYATNIPPHNLNEVIDALIYRIDHPNC----SVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 266 EQ-EGTRQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDLKwGMRIVVKLKRDAVPRVVLNNLYKHSQLQT 344
Cdd:TIGR01061 242 EVnKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRN-GIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 345 SFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSATVDTART 424
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 425 GLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGDDRRTQI- 503
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIe 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 504 -VAAEGDVTEEDLIARENVVVTITSTGYAKRTKVDAYKAQRRGGKGvrgadLKQDDIVRHFFVCSTHDWILFFTNKGRVY 582
Cdd:TIGR01061 481 dFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFG-----SKDDDILFAQTIANTTDQILIFTSLGNII 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 583 RLKAYELPEATRAARGQHVANLLEFQPEERIAEVLQIQSYQ-DSPYLVLATSEGKVKKSRLEDYESAR-SAGLIAINLRE 660
Cdd:TIGR01061 556 NIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVLASKLGMVKRIELTELNIKRnSKATLCIKLKD 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 661 GDSLIGARLCSADDDLLLVSERGQAIRFtaSDDALRPMGRATAGVQGMRFKGDDKLLSMVVVEEEHNLLVATTGGFGKKT 740
Cdd:TIGR01061 636 KDHLISAFLQQKDKLICLVSDLGYALVF--HTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFEANESLVLLTQRGSVKRL 713
|
730 740
....*....|....*....|....
gi 1093454911 741 KLSEYTPQNRG--GMGVLTLKYDP 762
Cdd:TIGR01061 714 SISELVVTSRAatGKKLLPLKKKP 737
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
24-728 |
1.89e-176 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 527.55 E-value: 1.89e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 24 IDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYDTMV 103
Cdd:TIGR01062 4 IDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEAMV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 104 RMAQPWSMRYPLVDGQGNFGS-RGDDGPAAMRYTEARLTPLAMEMVRDIRENTVDFQPNYDGRTTEPVILPSRVPQLLMN 182
Cdd:TIGR01062 84 LMAQPFSYRYPLVDGQGNWGApDDPKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 183 GSGGIAVGMATNIPPHNLREVADAINWCLDNPdadeKTTLDAVMERIKGPDFPTAAQIVGDKG-IKEAYTTGRGSIRMRG 261
Cdd:TIGR01062 164 GTTGIAVGMATDIPPHNLHELADAALYLIDNP----KAGLDDILNIVQGPDFPTEAEIIDKAEeIRKIYETGRGSFRMRA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 262 VTSIEQegtrQSIVITELPYQVNPDRMIANIADQVKDGRLQGIASIDDESDLKWGMRIVVKLKRDAV-PRVVLNNLYKHS 340
Cdd:TIGR01062 240 RWKKED----GQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVdPDIVMEHLFATT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 341 QLQTSFGANMLAI-VDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAHILRGLVKALDMLDEVIALIRRSatv 419
Cdd:TIGR01062 316 DLEKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREE--- 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 420 DTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIADLKDILANPDRQRAIVKEELTEVVEKYGDDR 499
Cdd:TIGR01062 393 DEPKTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLAR 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 500 RTQIVAAE--GDVTEEDLIARENVVVTITSTGYAKRTK---VDAykaqrrggkgvRGADLKQDDIVRHFFVCSTHDWILF 574
Cdd:TIGR01062 473 RSSLEEREeaKQVSEIDMIPKEPVTIILSKMGWVRSAKghdIDL-----------STLKYKAGDSEKAIIEGKSNQKVVF 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 575 FTNKGRVYRLKAYELPEATraARGQHVANLLEFQPEERIAEVLQiqsYQDSPYLVLATSEGKVKKSRLEDYESARSAGLI 654
Cdd:TIGR01062 542 IDSTGRSYALDPDNLPSAR--GQGEPLTGKLLLPIGATITNILM---YSPNQLLLMASDAGYGFLCNFNDLIARNKAGKA 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 655 AINLREGDSLIGARLCSADDDLLL-VSERGQAIRFTASDdalRPMGRATAGVQGMRFK------GDDKLLSMVVVEEEHN 727
Cdd:TIGR01062 617 LINLPENASVIAPLPVNGDSDMIAaITEAGRMLVFPIDD---LPELSKGKGNKLIRIPsanakrGEDGLLDLKIFNKQDG 693
|
.
gi 1093454911 728 L 728
Cdd:TIGR01062 694 L 694
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
21-135 |
2.04e-73 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 262.35 E-value: 2.04e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 21 VRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSDTMGNYHPHGDIAIYD 100
Cdd:NF038098 2 IEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYD 81
|
90 100 110
....*....|....*....|....*....|....*
gi 1093454911 101 TMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRY 135
Cdd:NF038098 82 TLVRMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
23-585 |
4.74e-65 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 229.98 E-value: 4.74e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 23 PIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMF--DNGyrperGYVKSAKPVSDTMgNYHPHGDIAIYD 100
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFemHDG-----KFHKVANVVGNTM-KYHPHGDASIYE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 101 TMVRMAQpwsmRYPLVDGQGNFGS--RGDDGPAAmRYTEARLTPLAMEMV--RDIREntvdFQPNYDGRTTEPVILPSRV 176
Cdd:PRK09631 75 ALVNLAN----KDLFIDKQGNFGNlfTGDPASAA-RYIECRLTPLAKEVLynKEITE----YEPSYDGRNNEPLCLPAKI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 177 PQLLMNGSGGIAVGMATNIPPHNLREVadainwcldnpdadekttLDAVMERIKG------PDFPTAaqivgdkGIKEA- 249
Cdd:PRK09631 146 PVILIQGAEGIAVGMATKILPHNFNEI------------------LQAVKSELLGesfalyPDFPTG-------GIVDVs 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 250 -YTTGRGSIRMRGVTSIEQEgtrQSIVITELPYQVNPDRMIANIADQVKDGRLQgIASIDDESDLKwgMRIVVKLKRDAV 328
Cdd:PRK09631 201 eYADGNGKVLVRAKIETKDE---KTIVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTAEN--VEIEIKLPRGVY 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 329 PRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAH--------ILRGLV 400
Cdd:PRK09631 275 ASEVIEALYAYTDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIFaktleqifIEERIY 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 401 KALDML---DEVIALIRRSATVDTARTglmgLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELEIA----DLKDI 473
Cdd:PRK09631 355 KRIETIsseEDVISIVLSELKPFKEEL----SRDVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKsvekNLKSI 430
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 474 lanpdRQRAIvkEELTEVVEKYGDD--RRTQIVAAEGDVTEEdlIARENVVVtitstGYAKRTkvdaykaqrrggkGVRG 551
Cdd:PRK09631 431 -----KGYAI--NFIDKLLAKYSKEypRKTEISLIKSVDVRE--IATKNLKV-----YYDLKT-------------GFVG 483
|
570 580 590
....*....|....*....|....*....|....*
gi 1093454911 552 ADLK-QDDIVRhffvCSTHDWILFFTNKGRvYRLK 585
Cdd:PRK09631 484 TSVKdGEFIGN----ASYYDKILVIRKDGT-YVVK 513
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
1-580 |
8.00e-63 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 227.96 E-value: 8.00e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 1 MSDDNNNDGSSFGSGVLGHQVRpidINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAM--FDNGYrpergYVK 78
Cdd:PRK12758 1 MSEEIENNQPEEESSEDEALTH---VSGMYKNWFLDYASYVILERAVPHIEDGLKPVQRRILHSMkeMDDGR-----YNK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 79 SAKPVSDTMgNYHPHGDIAIYDTMVRMAQpwsmRYPLVDGQGNFGS-RGDDGPAAMRYTEARLTPLAMEMVrdIRENTVD 157
Cdd:PRK12758 73 VANVVGHTM-QYHPHGDASIGDALVQLGQ----KDLLIDTQGNWGNiLTGDGAAAPRYIEARLSKFALEVV--FNPKTTE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 158 FQPNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDNpdadEKTTLdavmerikGPDFPTA 237
Cdd:PRK12758 146 WQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVGLSTKILPHNFNELIDASIAYLKG----KEFKL--------YPDFPTG 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 238 AQI-VGDkgikeaYTTGR--GSIRMRGvtSIEQEgTRQSIVITELPYQVNPDRMIANIADQVKDGRLQgIASIDDESDLK 314
Cdd:PRK12758 214 GIIdVSN------YNDGErgGRVRVRA--KIEKL-DKKTLVITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTAAD 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 315 wgMRIVVKLKRDAVPRVVLNNLYKHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYVAHQIEVIVRRTQYRLDEKEKRAH 394
Cdd:PRK12758 284 --VEILVHLAPGVSPDKTIDALYAFTDCEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWH 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 395 ------------ILRGLVKALDMlDEVIALIRRSATVDTARTglmglldIDEIQADAILAM---QLRRLAALERQKIIDE 459
Cdd:PRK12758 362 faslekifieerIYKEIEEAETW-EAVIEAIDKGLEPFKKQF-------IREVTEDDIVRLteiKIKRISKFDSDKADEL 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 460 LAEIELEIADLKDILANpdrqraIVK---EELTEVVEKYGDD--RRTQIVAAEgdvteedliarenvvvTITSTGYAKR- 533
Cdd:PRK12758 434 IARLEAEIAEVKHHLAH------LTDyaiAYFTNLKKKYGKGreRKTEIRNFD----------------TIEATKVVEAn 491
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1093454911 534 TKVDAYKAQrrggkGVRGADLKQDDIVrhfFVCSTHDWILFFTNKGR 580
Cdd:PRK12758 492 QKLYVNREE-----GFIGTGLKKDEYV---ADCSDIDDVIVFRRDGK 530
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
25-503 |
1.43e-47 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 176.62 E-value: 1.43e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 25 DINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFdngyRPERGYV-KSAKPVSDTMGnYHPHGDIAIYDTMV 103
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLF----RMDDGKMhKVANIAGRTMA-LHPHGDAPIVEALV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 104 RMAQpwsmRYPLVDGQGNFGSRGDDGP-AAMRYTEARLTPLAmemvRDIRENT--VDFQPNYDGRTTEPVILPSRVPQLL 180
Cdd:PRK09630 78 VLAN----KGYLIDTQGNFGNPLTGDPhAAARYIEARLSPLA----KEVLFNTdlMTFHDSYDGREKEPDILPAKLPLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 181 MNGSGGIAVGMATNIPPHNLREVADAINWCLDnpdaDEKTTLdavmerikGPDFPTAaqivgdkGIKEA--YTTGRGSIR 258
Cdd:PRK09630 150 LHGVDGIAVGMTTKIFPHNFCELLEAQIAILN----DQPFTL--------LPDFPSG-------GTMDAseYQDGLGSIT 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 259 MRGVTSIEQEGTrqsIVITELPYQVNPDRMIANIADQVKDGRLQgIASIDDES-DLKwgmRIVVKLKRDAVPRVVLNNLY 337
Cdd:PRK09630 211 LRASIDIINDKT---LLIKEICPSTTTETLIRSIENAAKRGIIK-IDSIQDFStDLP---HIEIKLPKGIYAKDLLRPLF 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 338 KHSQLQTSFGANMLAIVDGVPRTLRIDQMVTLYvAHQIEVIVRRTQYRLDEKEKRAHILRGLV------KALDMLDEVIA 411
Cdd:PRK09630 284 THTECQVILTSRPTAIYQNKPVETSISEILRLH-TETLQGYLKKELLILEDSLSREHYHKTLEyifikhKLYDTVREMLS 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 412 LIRRSATVDTARTGLMGLLD--IDEI------QADAILA-MQLRRLAALERQKIIDELAEIELEIADLKDILANpdrQRA 482
Cdd:PRK09630 363 KRKTSPSSSDLHNAVLEALTpfLDTLptpvdkQATAQLAsLTIKKILCFNENSYTKELACIEKKQAAVQKDLSQ---LKK 439
|
490 500
....*....|....*....|...
gi 1093454911 483 IVKEELTEVVEKYGD--DRRTQI 503
Cdd:PRK09630 440 YTVKYLKGLLETYGQlgHRKTQI 462
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
20-474 |
8.65e-45 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 167.54 E-value: 8.65e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 20 QVRPIDINEEMQSSYIDYAMSVIVGRALPEIRDGLKPVHRRILYAMFDNGYRPERGYVKSAKPVSD-TMGNYHpHGDIAI 98
Cdd:PHA02592 2 QLKERSLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGvADLGYH-HGETSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 99 YDTMVRMAQPWSMRYPLVDGQGNFGSRGDDGPAAMRYTEARLTPLAMEMVRDIrentvDFQPNY-DGRTTEPVILPSRVP 177
Cdd:PHA02592 81 QDAGALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVHDNFRKIYKDE-----DLAPVHeDPEHIPPAFYLPIIP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 178 QLLMNGSGGIAVGMATNIPPHnlrevadainwcldnpdaDEKTTLDAVMERIKGPDFPTaaqivgdkgIKEAYTTGRGSI 257
Cdd:PHA02592 156 MVLLNGVSGIATGYATNILPH------------------SPKSVIKAVLAALNGKDITE---------PKVQFPEFKGEV 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 258 RMRGVTSIEQEGT-----RQSIVITELPYQVNPDRMIAnIADQVKDGRLqgIASIDDESDLKWgmRIVVKLKRDAVPRVV 332
Cdd:PHA02592 209 VEIEPGSYEIRGTyelngKTKLHITEIPVKYDRETYVA-VLDPLEEKGK--IVSYDDCTEDGF--RFKVTLKREENEEAT 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 333 LNNLYKHSQLQTSFGANMLAIV-DGVPRtlRIDQMVTL---YVAHQIEVIVRRTQYRLDEKEKRAHILrgLVKAL---DM 405
Cdd:PHA02592 284 HEKIMKDFGLIERVSQNITVINeNGKLK--VYENAEDLirdFVEIRKTYVQKRIQYEIKETEEAFDLA--LAKAEfikRV 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 406 LDEVIALIRRSatvDTARTGLMGLLDIDEIQADAILAMQLRRLAALERQKIIDELAEIELE-------------IADLKD 472
Cdd:PHA02592 360 IAGEIVLQGKT---RSELTEELSDNKDFGEYADKLVAMNIYSMTSDEREKLQKEAEELEKEheywkkttakkeyIKDLEE 436
|
..
gi 1093454911 473 IL 474
Cdd:PHA02592 437 LK 438
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
45-280 |
6.39e-22 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 102.43 E-value: 6.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 45 RALPEIRDGLKPVHRRILYAMFDNGYRPE------RGYV--KSAkpvsdtmgnYHpHGDIAIYDTMVRMAQPW--SMRYP 114
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACFKRNLKNEikvaqlSGYVseHSA---------YH-HGEQSLQQTIVGMAQNFvgSNNIN 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 115 LVDGQGNFGSR---GDDGPAAmRYTEARLTPLAmemvRDIRENTVDFQPNY---DGRTTEP-----VIlpsrvPQLLMNG 183
Cdd:PTZ00108 750 LLYPCGQFGSRlqgGKDHAAA-RYIFTKLSKIT----RYIFPEEDDPILDYledDGQSVEPfyyvpII-----PMVLVNG 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 184 SGGIAVGMATNIPPHNLREVADAINWCLDNpdaDEKTTLDavmerikgpdfPTAaqiVGDKGIKEayTTGRGSIRMRGVT 263
Cdd:PTZ00108 820 AEGIGTGFSTSIPNYNPLDIIDNLRRRLNG---EEVRPLV-----------PWY---RGFKGTIE--RNPKGKFISKGIY 880
|
250
....*....|....*..
gi 1093454911 264 SIEQEGTrqsIVITELP 280
Cdd:PTZ00108 881 EKVPDGT---VEITELP 894
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
26-401 |
8.97e-21 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 98.24 E-value: 8.97e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 26 INEEMqssyIDYAMSVIVgRALPEIRDGLKPVHRRILYAMFDNGYRPE------RGYV--KSAkpvsdtmgnYHpHGDIA 97
Cdd:PLN03128 659 INKEL----ILFSQADLA-RSIPSMVDGLKPSQRKVLFACFKRNLKSEikvaqlSGYVaeHSA---------YH-HGEAS 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 98 IYDTMVRMAQPW--SMRYPLVDGQGNFGSR---GDDGpAAMRYTEARLTPLAmemvRDIRENTVDFQPNY---DGRTTEP 169
Cdd:PLN03128 724 LASTIIGMAQDFvgSNNINLLTPSGQFGTRlqgGKDA-ASARYIFTRLSPIT----RALFPKDDDVLLNYlneDGQSIEP 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 170 VILPSRVPQLLMNGSGGIAVGMATNIPPHNLREVADAINWCLDnpdaDEKTTldavmerikgPDFPTAAQIVGDkgIKEA 249
Cdd:PLN03128 799 EWYCPIIPMVLVNGSEGIGTGWSTFIPNYNPRDIIANIRRLLR----GEELE----------PMHPWYRGFKGT--ITEV 862
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 250 YTTGRGSIRMRGVtsIEQEGTRqSIVITELP-------YQVNPDRMIANIADQ---VKDGRlqgiasiDDESDLKwgMRI 319
Cdd:PLN03128 863 STSRSGSYTVTGI--IEQIGDT-TIRITELPvrkwtqdYKEFLEALLTGTKKKepeIKDFK-------ENHTDTT--VHF 930
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 320 VVKLKRDAVPRVVLNNLYKHSQLQTSFG-ANMLAI-VDGVPRT-------------LRIDqmvtLYVAhQIEVIVRRTQY 384
Cdd:PLN03128 931 TVTLSEEKMARALAEGLEKKFKLSTTIStSNMHLFdKDGKIKKydspedileeffhLRLD----LYVK-RKEVLLENLEY 1005
|
410
....*....|....*..
gi 1093454911 385 RLDEKEKRAHILRGLVK 401
Cdd:PLN03128 1006 ELKKLDNKARFILAVVK 1022
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
45-280 |
1.20e-15 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 81.83 E-value: 1.20e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 45 RALPEIRDGLKPVHRRILYAMFdngyrpERGYVKSAKP------VSDtMGNYHpHGDIAIYDTMVRMAQPW--SMRYPLV 116
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSF------KRNFVKEAKVaqlsgyVSE-HSAYH-HGEQSLASTIIGMAQDFvgSNNINLL 769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 117 DGQGNFGSRGDDGP--AAMRYTEARLTPLAMEMVRDIRENTVDFQpNYDGRTTEPVILPSRVPQLLMNGSGGIAVGMATN 194
Cdd:PLN03237 770 LPNGQFGTRLQGGKdhASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTF 848
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1093454911 195 IPPHNLREVADAINWCLDnpdadekttlDAVMERIKgPDFPtaaqivGDKGIKEAYTTGRGSIRMRgVTSIEQEGTRQSI 274
Cdd:PLN03237 849 IPNYNPRDIVANIRRLLN----------GESMEPMH-PWYR------GFKGTIEKTASKEGGCTYT-ITGLYEEVDETTL 910
|
....*.
gi 1093454911 275 VITELP 280
Cdd:PLN03237 911 RITELP 916
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
522-567 |
4.19e-11 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 58.65 E-value: 4.19e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1093454911 522 VVTITSTGYAKRTKVDAYKAQRRGGKGVRGADLKQDDIVRHFFVCS 567
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
674-723 |
1.21e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 57.11 E-value: 1.21e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1093454911 674 DDLLLVSERGQAIRFTASDdaLRPMGRATAGVQGMRFKGDDKLLSMVVVE 723
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSE--IREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
777-820 |
9.13e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 54.80 E-value: 9.13e-10
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1093454911 777 DEIFAVTSAGDIIRTNVNEIRATSRATKGVRLVNLADGVELLAI 820
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSV 44
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
570-619 |
2.33e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 50.95 E-value: 2.33e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1093454911 570 DWILFFTNKGRVYRLKAYELPEATRAARGQHVANLLEfqpEERIAEVLQI 619
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE---GDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
627-671 |
2.62e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 47.87 E-value: 2.62e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1093454911 627 YLVLATSEGKVKKSRLEDYESAR--SAGLIAINLREGDSLIGARLCS 671
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
726-774 |
1.60e-05 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 42.86 E-value: 1.60e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1093454911 726 HNLLVATTGGFGKKTKLSEYTPQNRGGMGVLTLKYDpKRGPLMGALVVD 774
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLK-EGDKVVSVLVVN 48
|
|
| PrfA |
COG0216 |
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ... |
454-502 |
9.29e-03 |
|
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors
Pssm-ID: 439986 [Multi-domain] Cd Length: 356 Bit Score: 39.21 E-value: 9.29e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1093454911 454 QKIIDELAEIELEIADlKDILANPDRQRAIVKE--ELTEVVEKYGDDRRTQ 502
Cdd:COG0216 7 EALEERYEELEALLSD-PEVISDQKRFRKLSKEyaELEPIVEAYREYKKLL 56
|
|
| |
