|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
7-840 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1616.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 7 EITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVY 86
Cdd:PRK05560 4 RIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 87 ETIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNL 166
Cdd:PRK05560 84 DALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 167 LVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQA 246
Cdd:PRK05560 164 LVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 247 DIEtdEKTGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQM 326
Cdd:PRK05560 244 EIE--EIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 327 QVSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEA 406
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 407 KAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQI 486
Cdd:PRK05560 402 KEGLME-----------------------------------RFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALI 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 487 AELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITENTADINIEDLINEENVVVTLSHQGYVKYQPLTDYEAQRRGGK 566
Cdd:PRK05560 447 ADLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGK 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 567 GKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPVREYEEGKF 646
Cdd:PRK05560 527 GVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKY 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 647 VFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRTATGVRGMK 726
Cdd:PRK05560 607 LFFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIK 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 727 LSDDDKVVSLIIPRGDG-DILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSERNGKVVGAIQVEETDQIMMITNAGTL 805
Cdd:PRK05560 687 LREGDEVVSMDVVREDSqEILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKL 766
|
810 820 830
....*....|....*....|....*....|....*
gi 1114045248 806 VRTRVSEVSIVGRNTQGVTLIRTTEGELVVGLQRV 840
Cdd:PRK05560 767 IRTRVSEISITGRNTQGVRLIRLDEGDKVVSVARV 801
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-837 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1505.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 1 MSD--IAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYH 78
Cdd:COG0188 1 MSDppPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 79 PHGDSAVYETIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAV 158
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 159 MPTRIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRG 238
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 239 KIYIRAQADIETDeKTGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLN 318
Cdd:COG0188 241 SIRVRAKAEIEEL-KRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 319 HLFSQTQMQVSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIR 398
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 399 QAPNPAEAKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDE 478
Cdd:COG0188 400 ASKDPDEAKEALME-----------------------------------RFGLSEIQAEAILDMRLRRLTGLEREKIEDE 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 479 YRDLLLQIAELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITENTADINIEDLINEENVVVTLSHQGYVKYQPLTDY 558
Cdd:COG0188 445 YAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTY 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 559 EAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPV 638
Cdd:COG0188 525 RAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPV 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 639 REYEEGKFVFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRT 718
Cdd:COG0188 605 KEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRT 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 719 ATGVRGMKLSDDDKVVSLIIPRGDGDILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSERNGKVVGAIQVEETDQIMM 798
Cdd:COG0188 685 ARGVRGIRLKEGDEVVGMAVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELML 764
|
810 820 830
....*....|....*....|....*....|....*....
gi 1114045248 799 ITNAGTLVRTRVSEVSIVGRNTQGVTLIRTTEGELVVGL 837
Cdd:COG0188 765 ITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
8-840 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1373.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYE 87
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 88 TIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLL 167
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 168 VNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQAD 247
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 248 IETDEKtGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQ 327
Cdd:TIGR01063 241 IEEDSK-GREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 328 VSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEAK 407
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 408 AALIAQpwdlgsvstmleragdsnvarpewlepqygvhdgkYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIA 487
Cdd:TIGR01063 400 TRLVER-----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 488 ELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITEN-TADINIEDLINEENVVVTLSHQGYVKYQPLTDYEAQRRGGK 566
Cdd:TIGR01063 445 DLEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDeSEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGK 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 567 GKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPVREYEEGKF 646
Cdd:TIGR01063 525 GVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLY 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 647 VFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRTATGVRGMK 726
Cdd:TIGR01063 605 LFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIK 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 727 LSDDDKVVSLIIPRGDGDILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSERNGKVVGAIQVEETDQIMMITNAGTLV 806
Cdd:TIGR01063 685 LKNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLI 764
|
810 820 830
....*....|....*....|....*....|....
gi 1114045248 807 RTRVSEVSIVGRNTQGVTLIRTTEGELVVGLQRV 840
Cdd:TIGR01063 765 RTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKV 798
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-510 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 715.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 30 VGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIVRLAQPFSMRYMLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 110 GSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVNGSSGIAVGMATNIPPHNLGE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 190 VIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQADIETDEktGRETIIVTEIPYQVN 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE--GRNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 270 KARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQVSFGINMVALHQ-GQPKLLNLK 348
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPnGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 349 EIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQApnpAEAKAALIAQPWdlgsvstmlerag 428
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELE------------- 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 429 dsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIAELLHILRSPERLMEVIREELN 508
Cdd:cd00187 383 -------------------KLGFSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELD 443
|
..
gi 1114045248 509 AI 510
Cdd:cd00187 444 EF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-500 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 654.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 11 VNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 91 RLAQPFSMRYMLVDGQGNFGSV-DGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 170 GSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINgrrgildayrtGRGKIYIRAQADIE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 250 TDektgrETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDES-DKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQV 328
Cdd:smart00434 230 DD-----NTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 329 SFGINMVALH-QGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKAR-DRAHILEALAVALANIDPVIEMIRQAPNPA-E 405
Cdd:smart00434 305 TFSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 406 AKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQ 485
Cdd:smart00434 385 AKEKLME-----------------------------------RFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKE 429
|
490
....*....|....*
gi 1114045248 486 IAELLHILRSPERLM 500
Cdd:smart00434 430 IEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-508 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 622.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 32 RALPDVRDGLKPVHRRVLFAMNVLGNDwNKPYKKSARVVGDVIGKYHPHGDSAVYETIVRLAQPFSMRYMLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 112 V-DGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVNGSSGIAVGMATNIPPHNLGEV 190
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 191 IDGCLAYVDNEDITIeeLMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQADIETdektgRETIIVTEIPYQVNK 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED-----RKTIVITELPYGVWT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 271 ARLIEKIAELVKDKRIEGISGLRDESDKdGMRIVVEIKRDAVGEVVLNHLFSQTQMQVSFGINMVALHQGQPKLLNLKEI 350
Cdd:pfam00521 233 SDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 351 ISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEAKAALIAQpwdlgsvstmleragds 430
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE----------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1114045248 431 nvarpewlepqygvhdgkyyLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIAELLHILRSPERLMEVIREELN 508
Cdd:pfam00521 375 --------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
7-840 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1616.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 7 EITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVY 86
Cdd:PRK05560 4 RIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 87 ETIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNL 166
Cdd:PRK05560 84 DALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 167 LVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQA 246
Cdd:PRK05560 164 LVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 247 DIEtdEKTGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQM 326
Cdd:PRK05560 244 EIE--EIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 327 QVSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEA 406
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 407 KAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQI 486
Cdd:PRK05560 402 KEGLME-----------------------------------RFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALI 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 487 AELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITENTADINIEDLINEENVVVTLSHQGYVKYQPLTDYEAQRRGGK 566
Cdd:PRK05560 447 ADLKDILASPERLLEIIKEELLEIKEKFGDPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGK 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 567 GKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPVREYEEGKF 646
Cdd:PRK05560 527 GVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKY 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 647 VFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRTATGVRGMK 726
Cdd:PRK05560 607 LFFATKNGTVKKTSLSEFSNIRSNGIIAINLDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIK 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 727 LSDDDKVVSLIIPRGDG-DILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSERNGKVVGAIQVEETDQIMMITNAGTL 805
Cdd:PRK05560 687 LREGDEVVSMDVVREDSqEILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKL 766
|
810 820 830
....*....|....*....|....*....|....*
gi 1114045248 806 VRTRVSEVSIVGRNTQGVTLIRTTEGELVVGLQRV 840
Cdd:PRK05560 767 IRTRVSEISITGRNTQGVRLIRLDEGDKVVSVARV 801
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-837 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1505.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 1 MSD--IAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYH 78
Cdd:COG0188 1 MSDppPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 79 PHGDSAVYETIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAV 158
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 159 MPTRIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRG 238
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 239 KIYIRAQADIETDeKTGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLN 318
Cdd:COG0188 241 SIRVRAKAEIEEL-KRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 319 HLFSQTQMQVSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIR 398
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 399 QAPNPAEAKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDE 478
Cdd:COG0188 400 ASKDPDEAKEALME-----------------------------------RFGLSEIQAEAILDMRLRRLTGLEREKIEDE 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 479 YRDLLLQIAELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITENTADINIEDLINEENVVVTLSHQGYVKYQPLTDY 558
Cdd:COG0188 445 YAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTY 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 559 EAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPV 638
Cdd:COG0188 525 RAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPV 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 639 REYEEGKFVFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRT 718
Cdd:COG0188 605 KEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRT 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 719 ATGVRGMKLSDDDKVVSLIIPRGDGDILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSERNGKVVGAIQVEETDQIMM 798
Cdd:COG0188 685 ARGVRGIRLKEGDEVVGMAVVDEEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELML 764
|
810 820 830
....*....|....*....|....*....|....*....
gi 1114045248 799 ITNAGTLVRTRVSEVSIVGRNTQGVTLIRTTEGELVVGL 837
Cdd:COG0188 765 ITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGDKVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
8-840 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1373.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYE 87
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 88 TIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLL 167
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 168 VNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQAD 247
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 248 IETDEKtGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQ 327
Cdd:TIGR01063 241 IEEDSK-GREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 328 VSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEAK 407
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 408 AALIAQpwdlgsvstmleragdsnvarpewlepqygvhdgkYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIA 487
Cdd:TIGR01063 400 TRLVER-----------------------------------FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 488 ELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITEN-TADINIEDLINEENVVVTLSHQGYVKYQPLTDYEAQRRGGK 566
Cdd:TIGR01063 445 DLEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDeSEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGK 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 567 GKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPVREYEEGKF 646
Cdd:TIGR01063 525 GVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLY 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 647 VFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRTATGVRGMK 726
Cdd:TIGR01063 605 LFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDGDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIK 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 727 LSDDDKVVSLIIPRGDGDILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSERNGKVVGAIQVEETDQIMMITNAGTLV 806
Cdd:TIGR01063 685 LKNEDFVVSLLVVSEESYLLIVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLI 764
|
810 820 830
....*....|....*....|....*....|....
gi 1114045248 807 RTRVSEVSIVGRNTQGVTLIRTTEGELVVGLQRV 840
Cdd:TIGR01063 765 RTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVSKV 798
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-772 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 864.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 1 MSDIAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPH 80
Cdd:PRK05561 3 DMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 81 GDSAVYETIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMP 160
Cdd:PRK05561 83 GDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 161 TRIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPT-AAIINGRRGILDAYRTGRGK 239
Cdd:PRK05561 163 ARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTgGEIITGRDGIRKAYETGRGS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 240 IYIRAQADIEtDEKTGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDG-MRIVVEIKRDAVG-EVVL 317
Cdd:PRK05561 243 IRVRARWEIE-DLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNRVDpEALM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 318 NHLFSQTQMQVSFGINMVALHQ-GQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEM 396
Cdd:PRK05561 322 NHLFATTDLESSYRVNMNAIGLdGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 397 IRQAPNPaeaKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLL 476
Cdd:PRK05561 402 IRESDEP---KANLMA-----------------------------------RFDLSEIQAEAILELRLRRLAKLEEIEIR 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 477 DEYRDLLLQIAELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITENTAD--INIEDLINEENVVVTLSHQGYVKyqp 554
Cdd:PRK05561 444 KEQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDPRRTPIEEAEEAiaIDEEALIPDEPVTVVLSKKGWVR--- 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 555 ltdyeaqRRGGKGKSAA--RIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEAsRGArGRPIINLLPLEQNERI 632
Cdd:PRK05561 521 -------RAKGHSIDASglSFKEGDSLLFAFEARTTDKLLLFTSTGRVYSLPVHELPSA-RGD-GEPLTGLVDLAPGEEI 591
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 633 TAILPvreYEEGKFVFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCV 712
Cdd:PRK05561 592 VHVLA---FDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSEL 668
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1114045248 713 RPMGRtATGVRGMKL-SDDDKVVSLIIPRGDGDILTVTENGYGKRTAQSEYPT--KNRATQGV 772
Cdd:PRK05561 669 PELGK-GKGVKLINLpKDDDGLVDLRVLNPEDGLVLLTAGKRKLKLKPSELEKyrGKRARRGR 730
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
30-510 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 715.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 30 VGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIVRLAQPFSMRYMLVDGQGNF 109
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 110 GSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVNGSSGIAVGMATNIPPHNLGE 189
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 190 VIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQADIETDEktGRETIIVTEIPYQVN 269
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE--GRNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 270 KARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQVSFGINMVALHQ-GQPKLLNLK 348
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPnGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 349 EIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQApnpAEAKAALIAQPWdlgsvstmlerag 428
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELE------------- 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 429 dsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIAELLHILRSPERLMEVIREELN 508
Cdd:cd00187 383 -------------------KLGFSEIQADAILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELD 443
|
..
gi 1114045248 509 AI 510
Cdd:cd00187 444 EF 445
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
8-803 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 662.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYE 87
Cdd:PRK13979 13 IIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 88 TIVRLAQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLL 167
Cdd:PRK13979 93 AMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 168 VNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQAD 247
Cdd:PRK13979 173 VNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 248 IETDEKtGRETIIVTEIPYQVNKARLIEKIAELVKDKR----IEGISGLRDESDKDGMRIVVEIKRDA---VGEVVLNHL 320
Cdd:PRK13979 253 IEKLEN-GRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESDRNGIRAVIEFKKSAdedVAEKVLKYL 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 321 FSQTQMQVSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQA 400
Cdd:PRK13979 332 YKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSS 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 401 PNPAEAKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYR 480
Cdd:PRK13979 412 KSKKDASENLIE-----------------------------------KFGFTDEQAEAILELMLYRLTGLEIVAFEKEYK 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 481 DLLLQIAELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITE--NTADINIEDLINEENVVVTLSHQGYVKYQPLTDY 558
Cdd:PRK13979 457 ELEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERRTSIIEddEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSY 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 559 eaqRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPE---ASRGARGRPIINLLPLEqNERITAI 635
Cdd:PRK13979 537 ---NRSNSNVEDIEYREGDFNKFLIQSNTKDTLLIFTDKGNMYQIKGINIPEfkwKEKGERLDEIIKGIDLE-SEKIIEA 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 636 LPVREYEEGK-FVFMaTASGTVKKTPLQDFSRPRSAgIIAVNLNEGDELIGVDLTDSTNEVMLFSADGK-----VVRfaE 709
Cdd:PRK13979 613 YSIEDFTPQKdFIFI-TDSGGIKKTSLDKFVTNYTK-LMALKLKKGEKLIKVKLVDRTREEKFIKIKTKkglsfTVE--E 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 710 DCVRPMGRTATGVRGMKLSDDDKVVSliiprgdgdILTVTENGYgkRTAQSEYPTKNratqgviSIKVSERNGKVVGAIQ 789
Cdd:PRK13979 689 PELEPVDRNIIGYQLFDLLPNDSIKK---------VDFCDNYEY--KEFYVNINKKG-------IIKISDKDNKSSISVF 750
|
810
....*....|....
gi 1114045248 790 VEETDQIMMITNAG 803
Cdd:PRK13979 751 TNSSKNLLIFSDEG 764
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
11-500 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 654.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 11 VNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIV 90
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 91 RLAQPFSMRYMLVDGQGNFGSV-DGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVN 169
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 170 GSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINgrrgildayrtGRGKIYIRAQADIE 249
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 250 TDektgrETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDES-DKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQV 328
Cdd:smart00434 230 DD-----NTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQT 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 329 SFGINMVALH-QGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKAR-DRAHILEALAVALANIDPVIEMIRQAPNPA-E 405
Cdd:smart00434 305 TFSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLAkE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 406 AKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQ 485
Cdd:smart00434 385 AKEKLME-----------------------------------RFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKE 429
|
490
....*....|....*
gi 1114045248 486 IAELLHILRSPERLM 500
Cdd:smart00434 430 IEDLEKILASEEWLN 444
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
13-772 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 622.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 13 IEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYETIVRL 92
Cdd:TIGR01061 6 LEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 93 AQPFSMRYMLVDGQGNFGSVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVNGSS 172
Cdd:TIGR01061 86 SQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 173 GIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQADIETDe 252
Cdd:TIGR01061 166 GIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEIEVN- 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 253 KTGRETIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQVSFGI 332
Cdd:TIGR01061 245 KNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQINYNF 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 333 NMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEAKAALIA 412
Cdd:TIGR01061 325 NMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENLID 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 413 qpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIAELLHI 492
Cdd:TIGR01061 405 -----------------------------------NFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQI 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 493 LRSPERLMEVIREELNAIKDQYNDPRRTEITE--NTADINIEDLINEENVVVTLSHQGYVKYQPLTDYEAQRRGGKGKsa 570
Cdd:TIGR01061 450 IASEKARNKLLKKQLEEYKKQFAQQRRSQIEDfiNQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGS-- 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 571 ariKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLEQNERITAILPVREYE-EGKFVFM 649
Cdd:TIGR01061 528 ---KDDDILFAQTIANTTDQILIFTSLGNIINIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVL 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 650 ATASGTVKKTPLQDFS-RPRSAGIIAVNLNEGDELIGVDLTDSTNEVMLFSADGKVVRFAEDCVRPMGRTATGVRGMKLS 728
Cdd:TIGR01061 605 ASKLGMVKRIELTELNiKRNSKATLCIKLKDKDHLISAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLK 684
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 1114045248 729 DDDKVVSLIIPRGDGDILTVTENGYGKRTAQSEYPTKNRATQGV 772
Cdd:TIGR01061 685 EDDQVKSGVIFEANESLVLLTQRGSVKRLSISELVVTSRAATGK 728
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
32-508 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 622.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 32 RALPDVRDGLKPVHRRVLFAMNVLGNDwNKPYKKSARVVGDVIGKYHPHGDSAVYETIVRLAQPFSMRYMLVDGQGNFGS 111
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFELLNL-DKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 112 V-DGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVNGSSGIAVGMATNIPPHNLGEV 190
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 191 IDGCLAYVDNEDITIeeLMEHITGPDFPTAAIINGRRGILDAYRTGRGKIYIRAQADIETdektgRETIIVTEIPYQVNK 270
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED-----RKTIVITELPYGVWT 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 271 ARLIEKIAELVKDKRIEGISGLRDESDKdGMRIVVEIKRDAVGEVVLNHLFSQTQMQVSFGINMVALHQGQPKLLNLKEI 350
Cdd:pfam00521 233 SDLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 351 ISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPNPAEAKAALIAQpwdlgsvstmleragds 430
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE----------------- 374
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1114045248 431 nvarpewlepqygvhdgkyyLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDLLLQIAELLHILRSPERLMEVIREELN 508
Cdd:pfam00521 375 --------------------LSEIQADYLLDMRLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
8-707 |
6.76e-172 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 516.00 E-value: 6.76e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 8 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDVIGKYHPHGDSAVYE 87
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 88 TIVRLAQPFSMRYMLVDGQGNFGSVDG-DSAAAMRYTEVRMAKIAHELLADLEKETVDFVPNYDGTEHIPAVMPTRIPNL 166
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 167 LVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEELMEHITGPDFPTAA-IINGRRGILDAYRTGRGKIYIRAQ 245
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAeIIDKAEEIRKIYETGRGSFRMRAR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 246 ADIETDEktgretIIVTEIPYQVNKARLIEKIAELVKDKRIEGISGLRDESD-KDGMRIVVEIKRDAVG-EVVLNHLFSQ 323
Cdd:TIGR01062 241 WKKEDGQ------IVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDhENPIRVVIVPRSNRVDpDIVMEHLFAT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 324 TQMQVSFGINM-VALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVALANIDPVIEMIRQAPN 402
Cdd:TIGR01062 315 TDLEKSYRLNMnMIGLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREEDE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 403 PaeaKAALIAqpwdlgsvstmleragdsnvarpewlepqygvhdgKYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYRDL 482
Cdd:TIGR01062 395 P---KTILME-----------------------------------RFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSEL 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 483 LLQIAELLHILRSPERLMEVIREELNAIKDQYNDPRRTEITE--NTADINIEDLINEENVVVTLSHQGYVKYQPLTDYEA 560
Cdd:TIGR01062 437 EKERAILEKILKSERELNQLVKKEIQADATKYGLARRSSLEEreEAKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDL 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 561 qrrggkgkSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEAsRGaRGRPIINLLPLEQNERITAILpvrE 640
Cdd:TIGR01062 517 --------STLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDNLPSA-RG-QGEPLTGKLLLPIGATITNIL---M 583
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1114045248 641 YEEGKFVFMATASGTVKKTPLQDFSRPRSAGIIAVNLNEGDELIG-VDLTDSTNEVMLFSADGKVVRF 707
Cdd:TIGR01062 584 YSPNQLLLMASDAGYGFLCNFNDLIARNKAGKALINLPENASVIApLPVNGDSDMIAAITEAGRMLVF 651
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
10-383 |
1.60e-64 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 228.82 E-value: 1.60e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 10 PVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRV---LFAMNvlgnDWNkpYKKSARVVGDVIgKYHPHGDSAVY 86
Cdd:PRK09631 1 MMDIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRIlhsLFEMH----DGK--FHKVANVVGNTM-KYHPHGDASIY 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 87 ETIVRLAQpfsmRYMLVDGQGNFGSV-DGDSAAAMRYTEVRMAKIAHELLadLEKETVDFVPNYDGTEHIPAVMPTRIPN 165
Cdd:PRK09631 74 EALVNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 166 LLVNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEelmehitgPDFPTAAIINgrrgiLDAYRTGRGKIYIRAQ 245
Cdd:PRK09631 148 ILIQGAEGIAVGMATKILPHNFNEILQAVKSELLGESFALY--------PDFPTGGIVD-----VSEYADGNGKVLVRAK 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 246 ADiETDEKtgreTIIVTEIPYQVNKARLIEKIAELVKDKRIEgISGLrdeSDKDGMRIVVEIK--RDAVGEVVLNHLFSQ 323
Cdd:PRK09631 215 IE-TKDEK----TIVIREIPFGTTTESLIASIEKAARKGKIK-ISSI---NDYTAENVEIEIKlpRGVYASEVIEALYAY 285
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 324 TQMQVSFGINMVALHQGQPKLLNLKEIISAFIRHRREVVTRRTIYElrkardRAHILEAL 383
Cdd:PRK09631 286 TDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELE------RAKLLEKI 339
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
18-277 |
1.06e-51 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 195.22 E-value: 1.06e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 18 KSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDwnkPYKKSARVVGDVIgKYHPHGDSAVYETIVRLAQpfs 97
Cdd:PRK12758 28 KNWFLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMDDG---RYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 98 mRYMLVDGQGNFGSV-DGDSAAAMRYTEVRMAKIAHELLadLEKETVDFVPNYDGTEHIPAVMPTRIPNLLVNGSSGIAV 176
Cdd:PRK12758 101 -KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 177 GMATNIPPHNLGEVIDGCLAYVDNEDITIEelmehitgPDFPTAAIIN------GRRGildayrtgrGKIYIRAQadIET 250
Cdd:PRK12758 178 GLSTKILPHNFNELIDASIAYLKGKEFKLY--------PDFPTGGIIDvsnyndGERG---------GRVRVRAK--IEK 238
|
250 260
....*....|....*....|....*..
gi 1114045248 251 DEKtgrETIIVTEIPYQVNKARLIEKI 277
Cdd:PRK12758 239 LDK---KTLVITEIPYGTTTSSLIDSI 262
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
12-351 |
1.50e-46 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 173.93 E-value: 1.50e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 12 NIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLgnDWNKPYKksarvVGDVIGK---YHPHGDSAVYET 88
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFRM--DDGKMHK-----VANIAGRtmaLHPHGDAPIVEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 89 IVRLAQpfsmRYMLVDGQGNFGS-VDGDSAAAMRYTEVRMAKIAHELLadLEKETVDFVPNYDGTEHIPAVMPTRIPNLL 167
Cdd:PRK09630 76 LVVLAN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 168 VNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDITIEelmehitgPDFPTAaiingrrGILDA--YRTGRGKIYIRAQ 245
Cdd:PRK09630 150 LHGVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFTLL--------PDFPSG-------GTMDAseYQDGLGSITLRAS 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 246 ADIETDektgrETIIVTEIPYQVNKARLIEKIAELVKDKRIEgISGLRDESdKDGMRIVVEIKRDAVGEVVLNHLFSQTQ 325
Cdd:PRK09630 215 IDIIND-----KTLLIKEICPSTTTETLIRSIENAAKRGIIK-IDSIQDFS-TDLPHIEIKLPKGIYAKDLLRPLFTHTE 287
|
330 340
....*....|....*....|....*.
gi 1114045248 326 MQVSFGINMVALHQGQPKLLNLKEII 351
Cdd:PRK09630 288 CQVILTSRPTAIYQNKPVETSISEIL 313
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
22-395 |
4.44e-45 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 168.70 E-value: 4.44e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 22 LDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKPYKKSARVVGDV--IGkYHpHGDSAVYETIVRLAQPFSMR 99
Cdd:PHA02592 17 LEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVadLG-YH-HGETSAQDAGALMANTWNNN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 100 YMLVDGQGNFGSVDGDSAAAMRYTEVRMakiaHELLADLEKETvDFVPNYDGTEHIPAV--MPTrIPNLLVNGSSGIAVG 177
Cdd:PHA02592 95 IPLLDGQGNFGSRLVQKAAAARYIFARV----HDNFRKIYKDE-DLAPVHEDPEHIPPAfyLPI-IPMVLLNGVSGIATG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 178 MATNIPPHNLGEVIDGCLAYVDNEDITIEElmehitgPDFPtaaiinGRRGilDAYRTGRGKIYIRAqadieTDEKTGRE 257
Cdd:PHA02592 169 YATNILPHSPKSVIKAVLAALNGKDITEPK-------VQFP------EFKG--EVVEIEPGSYEIRG-----TYELNGKT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 258 TIIVTEIPYQVNKARLIEKIAELVKDKRIEGIsglrDESDKDGMRIVVEIKRDAVGEVVLNHLFSQTQMQVSFGINMVAL 337
Cdd:PHA02592 229 KLHITEIPVKYDRETYVAVLDPLEEKGKIVSY----DDCTEDGFRFKVTLKREENEEATHEKIMKDFGLIERVSQNITVI 304
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 338 HQ-GQPKLL-NLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEALAVAlanIDPVIE 395
Cdd:PHA02592 305 NEnGKLKVYeNAEDLIRDFVEIRKTYVQKRIQYEIKETEEAFDLALAKAEF---IKRVIA 361
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
32-524 |
9.31e-26 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 114.76 E-value: 9.31e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 32 RALPDVRDGLKPVHRRVLFAMnvlgndWNKPYKKSARVVgDVIG------KYHpHGDSAVYETIVRLAQPF----SMRYM 101
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFAC------FKRNLKNEIKVA-QLSGyvsehsAYH-HGEQSLQQTIVGMAQNFvgsnNINLL 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 102 LVDGQgnFGS--VDGDSAAAMRYTEVRMAKIA----HEllADleketvDFVPNY---DGTE-----HIPAvmptrIPNLL 167
Cdd:PTZ00108 752 YPCGQ--FGSrlQGGKDHAAARYIFTKLSKITryifPE--ED------DPILDYledDGQSvepfyYVPI-----IPMVL 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 168 VNGSSGIAVGMATNIPPHNLGEVIDGCLAYVDNEDItieelmehitgpdfptaaiingrRGILDAYRTGRGKIYIRAQAD 247
Cdd:PTZ00108 817 VNGAEGIGTGFSTSIPNYNPLDIIDNLRRRLNGEEV-----------------------RPLVPWYRGFKGTIERNPKGK 873
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 248 IETD---EKTGRETIIVTEIPYQVNKARLIEKIAELVKDKRiEGISGLRDESDKDGMRIVVEIKRDAVGEVVLNHLFSQT 324
Cdd:PTZ00108 874 FISKgiyEKVPDGTVEITELPIGKWTEDYKEFLESETLKEK-DVIVDYRDYSTANTVHFTVKLNDGVLEQWEEEGIEKVF 952
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 325 QMQVSFGI-NMVAL-HQGQ-PKLLNLKEIISAFIRHRREVVTRRTIYELRKARDRAHILEalavalaNIDPVIEMIRQ-- 399
Cdd:PTZ00108 953 KLKSTISTtNMVLFdENGKiKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLS-------NKVRFIKHVINge 1025
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 400 -----APnpaeaKAALIAQPWDLGSVS--------------TMLERAGDSNVARPEWLEPQYGVHDGKYYLteqqaqaiL 460
Cdd:PTZ00108 1026 lvitnAK-----KKDLVKELKKLGYVRfkdiikkksekitaEEEEGAEEDDEADDEDDEEELGAAVSYDYL--------L 1092
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1114045248 461 DLRLQKLTgLEH-EKLLDEYRDLLLQIAELLHilRSPERLMeviREELNAIKDQYNDPRRTEITE 524
Cdd:PTZ00108 1093 SMPIWSLT-KEKvEKLNAELEKKEKELEKLKN--TTPKDMW---LEDLDKFEEALEEQEEVEEKE 1151
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
32-434 |
1.54e-21 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 100.94 E-value: 1.54e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 32 RALPDVRDGLKPVHRRVLFAmnVLGNDWnKPYKKSARVVGDVI--GKYHpHGDSAVYETIVRLAQPF--SMRYMLVDGQG 107
Cdd:PLN03128 673 RSIPSMVDGLKPSQRKVLFA--CFKRNL-KSEIKVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFvgSNNINLLTPSG 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 108 NFGS--VDGDSAAAMRYTEVRMAKIA----HE----LLADLEKETVDFVPNYdgtehipaVMPTrIPNLLVNGSSGIAVG 177
Cdd:PLN03128 749 QFGTrlQGGKDAASARYIFTRLSPITralfPKdddvLLNYLNEDGQSIEPEW--------YCPI-IPMVLVNGSEGIGTG 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 178 MATNIPPHNLGEVIDGCLAYVDNEDIT-IEELMEHITGPDFPTAAIINGRrgildaYRTGrGKIyiraqadietdEKTGR 256
Cdd:PLN03128 820 WSTFIPNYNPRDIIANIRRLLRGEELEpMHPWYRGFKGTITEVSTSRSGS------YTVT-GII-----------EQIGD 881
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 257 ETIIVTEIPYQV---NKARLIEKIAELVKDKRIEgISGLRDESDKDGMRIVVEIKRDAVGEVV---LNHLFS-QTQMQVS 329
Cdd:PLN03128 882 TTIRITELPVRKwtqDYKEFLEALLTGTKKKEPE-IKDFKENHTDTTVHFTVTLSEEKMARALaegLEKKFKlSTTISTS 960
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 330 fgiNMVAL-HQGQPKLLNLKE-IISAFIRH-------RREVVTRRTIYELRKARDRAH-ILEALAVAL-------ANIDP 392
Cdd:PLN03128 961 ---NMHLFdKDGKIKKYDSPEdILEEFFHLrldlyvkRKEVLLENLEYELKKLDNKARfILAVVKGEIvvnnrkrAELLA 1037
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1114045248 393 VIEMIRQAPNPAEAKAALIAQPWDLGSVSTMLERAGDSNVAR 434
Cdd:PLN03128 1038 ELEEKGFDKFPKTAKISETNVVGDRDGEASEEEEASDNELAK 1079
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
32-192 |
1.10e-13 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 75.67 E-value: 1.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 32 RALPDVRDGLKPVHRRVLFAmnvlgnDWNKPYKKSARV---VGDV--IGKYHpHGDSAVYETIVRLAQPF--SMRYMLVD 104
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFC------SFKRNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNNINLLL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1114045248 105 GQGNFG--SVDGDSAAAMRYTEVRMAKIAHELLADLEKETVDFVpNYDGTEHIPA-VMPTrIPNLLVNGSSGIAVGMATN 181
Cdd:PLN03237 771 PNGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTwYMPI-IPTVLVNGAEGIGTGWSTF 848
|
170
....*....|.
gi 1114045248 182 IPPHNLGEVID 192
Cdd:PLN03237 849 IPNYNPRDIVA 859
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
693-738 |
6.36e-12 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 60.96 E-value: 6.36e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1114045248 693 NEVMLFSADGKVVRFAEDCVRPMGRTATGVRGMKLSDDDKVVSLII 738
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
794-840 |
8.39e-11 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 57.88 E-value: 8.39e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1114045248 794 DQIMMITNAGTLVRTRVSEVSIVGRNTQGVTLIRTTEGELVVGLQRV 840
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
744-791 |
8.86e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 54.80 E-value: 8.86e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1114045248 744 DILTVTENGYGKRTAQSEYPTKNRATQGVISIKVSErNGKVVGAIQVE 791
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE-GDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
589-639 |
2.10e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 53.65 E-value: 2.10e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1114045248 589 DTILCFSSRGRLYWMKVYQLPEASRGARGRPIINllpLEQNERITAILPVR 639
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
541-586 |
2.57e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 50.56 E-value: 2.57e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1114045248 541 VVTLSHQGYVKYQPLTDYEAQRRGGKGKSAARIKEEDFIDRLLVAN 586
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
645-690 |
1.83e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 45.56 E-value: 1.83e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1114045248 645 KFVFMATASGTVKKTPLQDFSRPR--SAGIIAVNLNEGDELIGVDLTD 690
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGrgAKGVKGINLKEGDKVVSVLVVN 48
|
|
| |
