NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1119538114|ref|WP_072494394|]
View 

MULTISPECIES: FAD-dependent monooxygenase [Rhizobium/Agrobacterium group]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 5-391 5.64e-108

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member PRK06475:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 400  Bit Score: 322.93  E-value: 5.64e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSLAT 84
Cdd:PRK06475    4 SPLIAGAGVAGLSAALELAARGWAVTIIEKAQELSEVGAGLQLAPNAMRHLERLGVADRLSGTGVTPKALYLMDGRKARP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  85 LLSLPVGAVARTRWGAPYGVLHRSTLQSALLQTVTDNPLCRLHLGKRIENATADV--IAATTFR-------DHDLIVGAD 155
Cdd:PRK06475   84 LLAMQLGDLARKRWHHPYIVCHRADLQSALLDACRNNPGIEIKLGAEMTSQRQTGnsITATIIRtnsvetvSAAYLIACD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 156 GVWSAARFAVPAApTATFSGNVAWRFTVAANAVPSAI-----NKSAVTAYLGSGGHIVAYPLKEVGGFNIVAIALGADPG 230
Cdd:PRK06475  164 GVWSMLRAKAGFS-KARFSGHIAWRTTLAADALPASFlsampEHKAVSAWLGNKAHFIAYPVKGGKFFNFVAITGGENPG 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 231 ATWraeSSGRQKALLLEQFRGFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAAQGAAMAIEDA 310
Cdd:PRK06475  243 EVW---SKTGDKAHLKSIYADWNKPVLQILAAIDEWTYWPLFEMADAQFVGPDRTIFLGDASHAVTPFAAQGAAMAIEDA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 311 FELAGTMVGSDAAAtlpapqALAAFEALRLPRIEKARKRASLNRFAYHATGPVRIARDFVFSTRPTDAFVKDFDWLYGYR 390
Cdd:PRK06475  320 AALAEALDSDDQSA------GLKRFDSVRKERIAAVAKRGQLNRFAYHATGIFALGRNMLFAIRSPESFLKDLDWLYGYD 393


                  .
gi 1119538114 391 A 391
Cdd:PRK06475  394 A 394
 
Name Accession Description Interval E-value
PRK06475 PRK06475
FAD-binding protein;
5-391 5.64e-108

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 322.93  E-value: 5.64e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSLAT 84
Cdd:PRK06475    4 SPLIAGAGVAGLSAALELAARGWAVTIIEKAQELSEVGAGLQLAPNAMRHLERLGVADRLSGTGVTPKALYLMDGRKARP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  85 LLSLPVGAVARTRWGAPYGVLHRSTLQSALLQTVTDNPLCRLHLGKRIENATADV--IAATTFR-------DHDLIVGAD 155
Cdd:PRK06475   84 LLAMQLGDLARKRWHHPYIVCHRADLQSALLDACRNNPGIEIKLGAEMTSQRQTGnsITATIIRtnsvetvSAAYLIACD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 156 GVWSAARFAVPAApTATFSGNVAWRFTVAANAVPSAI-----NKSAVTAYLGSGGHIVAYPLKEVGGFNIVAIALGADPG 230
Cdd:PRK06475  164 GVWSMLRAKAGFS-KARFSGHIAWRTTLAADALPASFlsampEHKAVSAWLGNKAHFIAYPVKGGKFFNFVAITGGENPG 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 231 ATWraeSSGRQKALLLEQFRGFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAAQGAAMAIEDA 310
Cdd:PRK06475  243 EVW---SKTGDKAHLKSIYADWNKPVLQILAAIDEWTYWPLFEMADAQFVGPDRTIFLGDASHAVTPFAAQGAAMAIEDA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 311 FELAGTMVGSDAAAtlpapqALAAFEALRLPRIEKARKRASLNRFAYHATGPVRIARDFVFSTRPTDAFVKDFDWLYGYR 390
Cdd:PRK06475  320 AALAEALDSDDQSA------GLKRFDSVRKERIAAVAKRGQLNRFAYHATGIFALGRNMLFAIRSPESFLKDLDWLYGYD 393


                  .
gi 1119538114 391 A 391
Cdd:PRK06475  394 A 394
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-385 1.43e-45

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 159.33  E-value: 1.43e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGK 80
Cdd:COG0654     1 MMRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRDGS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  81 SLATLLSLPVGavartRWGAPYG-VLHRSTLQSALLQTVTDNPLcRLHLGKRIENATADVIAAT-TFRD-----HDLIVG 153
Cdd:COG0654    81 DGRVLARFDAA-----ETGLPAGlVVPRADLERALLEAARALGV-ELRFGTEVTGLEQDADGVTvTLADgrtlrADLVVG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 154 ADGVWSAARFAVPAAPT-ATFSGNVAWRFTVAAnavpsainksavtaylgsgghivayplkevggfnivaialgadpgat 232
Cdd:COG0654   155 ADGARSAVRRLLGIGFTgRDYPQRALWAGVRTE----------------------------------------------- 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 233 wraessgrqkalLLEQFRGFSPDIVRLLDSSeNPTFWPLYQAGPGRWHNGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFE 312
Cdd:COG0654   188 ------------LRARLAAAGPRLGELLELS-PRSAFPLRRRRAERWRRGR-VVLLGDAAHTMHPLGGQGANLALRDAAA 253

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1119538114 313 LAGTMVgsDAAATLPAPQALAAFEALRLPRIEKARKRASLNRFAYHATGP-VRIARDFVFSTRPTDAFVKDFDW 385
Cdd:COG0654   254 LAWKLA--AALRGRDDEAALARYERERRPRAARVQRAADALGRLFHPDSPpLRLLRNAGLRLLDRLPPLKGGGL 325
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 6-350 3.17e-14

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 73.13  E-value: 3.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSLAtl 85
Cdd:pfam01494   4 VLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPRAHGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRR-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  86 lslPVGAVARTRWGAPYGvlhrstlqsaLLQTVTDNPL--------CRLHLGKRIENATADVIAAT-TFRDH-------- 148
Cdd:pfam01494  82 ---RADLDFLTSPPRVTV----------YPQTELEPILvehaeargAQVRFGTEVLSLEQDGDGVTaVVRDRrdgeeytv 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 149 --DLIVGADGVWSAARFAVPaaptATFSGNVAWRFTVaANAVPSAINksaVTAYLGSGGHIVAYPLKEVGGFNIVAIALG 226
Cdd:pfam01494 149 raKYLVGCDGGRSPVRKTLG----IEFEGFEGVPFGS-LDVLFDAPD---LSDPVERAFVHYLIYAPHSRGFMVGPWRSA 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 227 ADPGATWRAESSGRQ------------KALLLEQFrgfspDIVRLLDSSENPTFWPLYQAGPGRWHNGRdTVLIGDAAHA 294
Cdd:pfam01494 221 GRERYYVQVPWDEEVeerpeeftdeelKQRLRSIV-----GIDLALVEILWKSIWGVASRVATRYRKGR-VFLAGDAAHI 294

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1119538114 295 MMPFAAQGAAMAIEDAFELagtmvGSDAAATL---PAPQALAAFEALRLPRIEKARKRA 350
Cdd:pfam01494 295 HPPTGGQGLNTAIQDAFNL-----AWKLAAVLrgqAGESLLDTYSAERLPVAWAVVDFA 348
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 6-341 3.02e-11

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 64.53  E-value: 3.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQ-----ISPNAARILATLGVLPAIEARWTEPVSVELASGK 80
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEATPLPAPADPGFDnrvsaLSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  81 SLATLLSL--------PVGAVARTRWgapygvlhrstLQSALLQTVTDNPLCRLHLGKRIENATADVIAAT-TFRDHD-- 149
Cdd:TIGR01988  82 GSFGALRFdadeigleALGYVVENRV-----------LQQALWERLQELPNVTLLCPARVVELPRHSDHVElTLDDGQql 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 150 ---LIVGADGVWSAAR--FAVPA--------APTATFS-----GNVAW-RFTvaanavpsainKSAVTAYLgsgghivay 210
Cdd:TIGR01988 151 rarLLVGADGANSKVRqlAGIPTtgwdygqsAVVANVKherphQGTAWeRFT-----------PTGPLALL--------- 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 211 PLKEvGGFNIV-------AIALGADPGATWRAEssgrqkalLLEQFRGFSPDIVrllDSSENPTFwPLYQAGPGRWHNGR 283
Cdd:TIGR01988 211 PLPD-NRSSLVwtlppeeAERLLALSDEEFLAE--------LQRAFGSRLGAIT---LVGERHAF-PLSLTHAKRYVAPR 277

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119538114 284 dTVLIGDAAHAMMPFAAQGAAMAIEDAFELAgtMVGSDAAAT---LPAPQALAAFEALRLP 341
Cdd:TIGR01988 278 -LALIGDAAHTIHPLAGQGLNLGLRDVAALA--EVLEDARRRgedIGSLRVLQRYERRRRF 335
 
Name Accession Description Interval E-value
PRK06475 PRK06475
FAD-binding protein;
5-391 5.64e-108

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 322.93  E-value: 5.64e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSLAT 84
Cdd:PRK06475    4 SPLIAGAGVAGLSAALELAARGWAVTIIEKAQELSEVGAGLQLAPNAMRHLERLGVADRLSGTGVTPKALYLMDGRKARP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  85 LLSLPVGAVARTRWGAPYGVLHRSTLQSALLQTVTDNPLCRLHLGKRIENATADV--IAATTFR-------DHDLIVGAD 155
Cdd:PRK06475   84 LLAMQLGDLARKRWHHPYIVCHRADLQSALLDACRNNPGIEIKLGAEMTSQRQTGnsITATIIRtnsvetvSAAYLIACD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 156 GVWSAARFAVPAApTATFSGNVAWRFTVAANAVPSAI-----NKSAVTAYLGSGGHIVAYPLKEVGGFNIVAIALGADPG 230
Cdd:PRK06475  164 GVWSMLRAKAGFS-KARFSGHIAWRTTLAADALPASFlsampEHKAVSAWLGNKAHFIAYPVKGGKFFNFVAITGGENPG 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 231 ATWraeSSGRQKALLLEQFRGFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAAQGAAMAIEDA 310
Cdd:PRK06475  243 EVW---SKTGDKAHLKSIYADWNKPVLQILAAIDEWTYWPLFEMADAQFVGPDRTIFLGDASHAVTPFAAQGAAMAIEDA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 311 FELAGTMVGSDAAAtlpapqALAAFEALRLPRIEKARKRASLNRFAYHATGPVRIARDFVFSTRPTDAFVKDFDWLYGYR 390
Cdd:PRK06475  320 AALAEALDSDDQSA------GLKRFDSVRKERIAAVAKRGQLNRFAYHATGIFALGRNMLFAIRSPESFLKDLDWLYGYD 393


                  .
gi 1119538114 391 A 391
Cdd:PRK06475  394 A 394
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
5-391 8.83e-66

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 214.52  E-value: 8.83e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSLAT 84
Cdd:PRK08163    6 PVLIVGGGIGGLAAALALARQGIKVKLLEQAAEIGEIGAGIQLGPNAFSALDALGVGEAARQRAVFTDHLTMMDAVDAEE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  85 LLSLPVGAVARTRWGAPYGVLHRSTLQSALLQTVTDNPLCRLHLGKRIENATADVIAATTFRDH------DLIVGADGVW 158
Cdd:PRK08163   86 VVRIPTGQAFRARFGNPYAVIHRADIHLSLLEAVLDHPLVEFRTSTHVVGIEQDGDGVTVFDQQgnrwtgDALIGCDGVK 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 159 SAARFAVPAAPtATFSGNVAWRFTVAANAVPSAINKSAVTAYLGSGGHIVAYPLKevGG--FNIVAIALGADPGATWRAE 236
Cdd:PRK08163  166 SVVRQSLVGDA-PRVTGHVVYRAVIDVDDMPEDLRINAPVLWAGPHCHLVHYPLR--GGeqYNLVVTFHSREQEEWGVKD 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 237 SSgrqKALLLEQFRGFSPDIVRLLDSSENPTFWPLYQAGP-GRWHNGRDTVLiGDAAHAMMPFAAQGAAMAIEDAFELAG 315
Cdd:PRK08163  243 GS---KEEVLSYFEGIHPRPRQMLDKPTSWKRWATADREPvAKWSTGRVTLL-GDAAHPMTQYMAQGACMALEDAVTLGK 318

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1119538114 316 TMVGSDAaatlPAPQALAAFEALRLPRIEKARKRASLNRFAYHATGPVRIARDFVFSTRPTDAFVKDFDWLYGYRA 391
Cdd:PRK08163  319 ALEGCDG----DAEAAFALYESVRIPRTARVVLSAREMGRIYHAKGVERQVRNLLWKGRTQEQFYDALEWLYGWKE 390
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-385 1.43e-45

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 159.33  E-value: 1.43e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGK 80
Cdd:COG0654     1 MMRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRDGS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  81 SLATLLSLPVGavartRWGAPYG-VLHRSTLQSALLQTVTDNPLcRLHLGKRIENATADVIAAT-TFRD-----HDLIVG 153
Cdd:COG0654    81 DGRVLARFDAA-----ETGLPAGlVVPRADLERALLEAARALGV-ELRFGTEVTGLEQDADGVTvTLADgrtlrADLVVG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 154 ADGVWSAARFAVPAAPT-ATFSGNVAWRFTVAAnavpsainksavtaylgsgghivayplkevggfnivaialgadpgat 232
Cdd:COG0654   155 ADGARSAVRRLLGIGFTgRDYPQRALWAGVRTE----------------------------------------------- 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 233 wraessgrqkalLLEQFRGFSPDIVRLLDSSeNPTFWPLYQAGPGRWHNGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFE 312
Cdd:COG0654   188 ------------LRARLAAAGPRLGELLELS-PRSAFPLRRRRAERWRRGR-VVLLGDAAHTMHPLGGQGANLALRDAAA 253

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1119538114 313 LAGTMVgsDAAATLPAPQALAAFEALRLPRIEKARKRASLNRFAYHATGP-VRIARDFVFSTRPTDAFVKDFDW 385
Cdd:COG0654   254 LAWKLA--AALRGRDDEAALARYERERRPRAARVQRAADALGRLFHPDSPpLRLLRNAGLRLLDRLPPLKGGGL 325
PRK06847 PRK06847
hypothetical protein; Provisional
 1-342 8.44e-42

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 150.79  E-value: 8.44e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEAR--WTEPVSVELAS 78
Cdd:PRK06847    2 AAVKKVLIVGGGIGGLSAAIALRRAGIAVDLVEIDPEWRVYGAGITLQGNALRALRELGVLDECLEAgfGFDGVDLFDPD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  79 GKSLATllsLPVGAVARTRWGAPYGVLhRSTLQSALLQTVTDNPLcRLHLGK---RIENATADViaATTFRD-----HDL 150
Cdd:PRK06847   82 GTLLAE---LPTPRLAGDDLPGGGGIM-RPALARILADAARAAGA-DVRLGTtvtAIEQDDDGV--TVTFSDgttgrYDL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 151 IVGADGVWSAARFAV-PAAPTATFSGNVAWRFTVAAnavPSAINKSavTAYLGSGGHIVAYPLKEVGGFNIVaiaLGADP 229
Cdd:PRK06847  155 VVGADGLYSKVRSLVfPDEPEPEYTGQGVWRAVLPR---PAEVDRS--LMYLGPTTKAGVVPLSEDLMYLFV---TEPRP 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 230 GATWRAESSGRQK-ALLLEQFRGFSPDIVR-LLDSSENPTFWPLYQ-AGPGRWHNGRdTVLIGDAAHAMMPFAAQGAAMA 306
Cdd:PRK06847  227 DNPRIEPDTLAALlRELLAPFGGPVLQELReQITDDAQVVYRPLETlLVPAPWHRGR-VVLIGDAAHATTPHLAQGAGMA 305

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1119538114 307 IEDAFELAGTMVGSDaaatlPAPQALAAFEALRLPR 342
Cdd:PRK06847  306 IEDAIVLAEELARHD-----SLEAALQAYYARRWER 336
PRK07538 PRK07538
hypothetical protein; Provisional
 6-343 9.71e-38

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 140.80  E-value: 9.71e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEpvSVELA-SGKSLAT 84
Cdd:PRK07538    3 VLIAGGGIGGLTLALTLHQRGIEVVVFEAAPELRPLGVGINLLPHAVRELAELGLLDALDAIGIR--TRELAyFNRHGQR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  85 LLSLPVGAVARTRWgaPYGVLHRSTLQSALLQTVTDnplcRL-----HLGKRIENA--TADVIAATTFRDH--------- 148
Cdd:PRK07538   81 IWSEPRGLAAGYDW--PQYSIHRGELQMLLLDAVRE----RLgpdavRTGHRVVGFeqDADVTVVFLGDRAggdlvsvrg 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 149 DLIVGADGVWSAARFAV-PAAPTATFSGNVAWRFTVAANAVPSAinKSAVTAylGSGGH-IVAYPLKEVGG------FNI 220
Cdd:PRK07538  155 DVLIGADGIHSAVRAQLyPDEGPPRWNGVMMWRGVTEAPPFLTG--RSMVMA--GHLDGkLVVYPISEPVDadgrqlINW 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 221 VAiALGADPGATWRAESSGRQ--KALLLEQFRGFS---PDIVRLLDSSENPTFWPLYQAGP-GRWHNGRDTvLIGDAAHA 294
Cdd:PRK07538  231 VA-EVRVDDAGAPRREDWNRPgdLEDFLPHFADWRfdwLDVPALIRAAEAIYEYPMVDRDPlPRWTRGRVT-LLGDAAHP 308

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1119538114 295 MMPFAAQGAAMAIEDAFELAGTMvgsdaAATLPAPQALAAFEALRLPRI 343
Cdd:PRK07538  309 MYPVGSNGASQAILDARALADAL-----AAHGDPEAALAAYEAERRPAT 352
PRK06753 PRK06753
hypothetical protein; Provisional
 6-387 7.11e-35

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 132.12  E-value: 7.11e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSlaTL 85
Cdd:PRK06753    3 IAIIGAGIGGLTAAALLQEQGHEVKVFEKNESVKEVGAGIGIGDNVIKKLGNHDLAKGIKNAGQILSTMNLLDDKG--TL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  86 LS---LPVGAVARTrwgapygvLHRSTLQSALLQTVTDNPLcrlHLGK---RIENATADVIaaTTFRDH-----DLIVGA 154
Cdd:PRK06753   81 LNkvkLKSNTLNVT--------LHRQTLIDIIKSYVKEDAI---FTGKevtKIENETDKVT--IHFADGeseafDLCIGA 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 155 DGVWSAARFAVPAAPTATFSGNVAWRFTVaanavPSAINKSAVTA--YLGSGGH--IVAYPLKEVGGFNIVAiALGADPg 230
Cdd:PRK06753  148 DGIHSKVRQSVNADSKVRYQGYTCFRGLI-----DDIDLKLPDCAkeYWGTKGRfgIVPLLNNQAYWFITIN-AKERDP- 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 231 atwraESSGRQKALLLEQFRGFSPDIVRLLD-SSENPTFW-------PLYQAGPGRwhngrdTVLIGDAAHAMMPFAAQG 302
Cdd:PRK06753  221 -----KYSSFGKPHLQAYFNHYPNEVREILDkQSETGILHhdiydlkPLKSFVYGR------IVLLGDAAHATTPNMGQG 289

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 303 AAMAIEDAFELAGTMvgsdaaATLPAPQALAAFEALRLPRIEKARKRA-SLNRFAYHATGPVRIARDFVFSTRPTDAFVK 381
Cdd:PRK06753  290 AGQAMEDAIVLANCL------NAYDFEKALQRYDKIRVKHTAKVIKRSrKIGKIAQIESKLLVALRNRVMKRMPNALAAG 363


                  ....*.
gi 1119538114 382 DFDWLY 387
Cdd:PRK06753  364 QTKFLY 369
PRK07236 PRK07236
hypothetical protein; Provisional
 1-342 4.56e-22

hypothetical protein; Provisional


Pssm-ID: 235980 [Multi-domain]  Cd Length: 386  Bit Score: 96.53  E-value: 4.56e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQ-AGELTEVGAGLQISPNAARILATLGV-------LPAIEARWtepv 72
Cdd:PRK07236    4 MSGPRAVVIGGSLGGLFAALLLRRAGWDVDVFERsPTELDGRGAGIVLQPELLRALAEAGValpadigVPSRERIY---- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  73 sveLASGKSLATLLSLPVgavARTRWGAPYGVLHRSTlqsallqtvtdnPLCRLHLGKRIENATADVIAAT-TFRD---- 147
Cdd:PRK07236   80 ---LDRDGRVVQRRPMPQ---TQTSWNVLYRALRAAF------------PAERYHLGETLVGFEQDGDRVTaRFADgrre 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 148 -HDLIVGADGVWSAARFAVPAAPTATFSGNVAWRFTVAANAVPS---AINKSAVTAYLGSGGHIVAYPLKEVGG------ 217
Cdd:PRK07236  142 tADLLVGADGGRSTVRAQLLPDVRPTYAGYVAWRGLVDEAALPPearAALRDRFTFQLGPGSHILGYPVPGEDGstepgk 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 218 --FNIV---------------------AIALGADPGAT---WRAESSGRQKALLLEQFRgfspdivRLLDSSENPTFWPL 271
Cdd:PRK07236  222 rrYNWVwyrnapageeldelltdrdgtRRPFSVPPGALrddVLAELRDDAAELLAPVFA-------ELVEATAQPFVQAI 294

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119538114 272 YQAGPGRWHNGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMvgSDAAATLPApqALAAFEALRLPR 342
Cdd:PRK07236  295 FDLEVPRMAFGR-VALLGDAAFVARPHTAAGVAKAAADAVALAEAL--AAAAGDIDA--ALAAWEAERLAV 360
PLN02927 PLN02927
antheraxanthin epoxidase/zeaxanthin epoxidase
 6-314 3.79e-21

antheraxanthin epoxidase/zeaxanthin epoxidase


Pssm-ID: 178515 [Multi-domain]  Cd Length: 668  Bit Score: 95.55  E-value: 3.79e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQagELTEV-GAG-----LQISPNAarilatLGVLPAIEARWTEPVSVE---- 75
Cdd:PLN02927   84 VLVAGGGIGGLVFALAAKKKGFDVLVFEK--DLSAIrGEGkyrgpIQIQSNA------LAALEAIDIDVAEQVMEAgcit 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  76 ------LASGKSLATLLSLPVGAVARTRWGAPYGVLHRSTLQSALLQTVTDNPLcrlhlgkRIENATAD----------V 139
Cdd:PLN02927  156 gdringLVDGISGSWYVKFDTFTPAASRGLPVTRVISRMTLQQILARAVGEDVI-------RNESNVVDfedsgdkvtvV 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 140 IAATTFRDHDLIVGADGVWSAARFAVPAAPTATFSGNVAwrFTVAANAVPSAINKSAVTAYLGSGGHIVAyplKEVGGFN 219
Cdd:PLN02927  229 LENGQRYEGDLLVGADGIWSKVRNNLFGRSEATYSGYTC--YTGIADFIPADIESVGYRVFLGHKQYFVS---SDVGGGK 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 220 IVAIALGADPGATwrAESSGRQKALLLEQFRGFSPDIVRLLDSSENPTFW--PLYQAGPG-RWHNGRDTvLIGDAAHAMM 296
Cdd:PLN02927  304 MQWYAFHEEPAGG--ADAPNGMKKRLFEIFDGWCDNVLDLLHATEEDAILrrDIYDRSPGfTWGKGRVT-LLGDSIHAMQ 380

                         330
                  ....*....|....*...
gi 1119538114 297 PFAAQGAAMAIEDAFELA 314
Cdd:PLN02927  381 PNMGQGGCMAIEDSFQLA 398
PRK07588 PRK07588
FAD-binding domain;
4-356 2.64e-16

FAD-binding domain;


Pssm-ID: 169028 [Multi-domain]  Cd Length: 391  Bit Score: 79.78  E-value: 2.64e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTE-------VGAGLQIspnAARilatLGVLPAIEARW--TEPVSV 74
Cdd:PRK07588    1 MKVAISGAGIAGPTLAYWLRRYGHEPTLIERAPELRTggymvdfWGVGYEV---AKR----MGITDQLREAGyqIEHVRS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  75 ELASGKSLATLLSlpvgAVARTRWGAPYGVLHRSTLQSALLQTVTDnplcrlhlgkRIENATADVIAA---------TTF 145
Cdd:PRK07588   74 VDPTGRRKADLNV----DSFRRMVGDDFTSLPRGDLAAAIYTAIDG----------QVETIFDDSIATidehrdgvrVTF 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 146 -----RDHDLIVGADGVWSAARFAV--PAAPTATFSGNVawrftVAANAVPSAINKSAVTA--YLGSGGHIVAYPLKE-V 215
Cdd:PRK07588  140 ergtpRDFDLVIGADGLHSHVRRLVfgPERDFEHYLGCK-----VAACVVDGYRPRDERTYvlYNEVGRQVARVALRGdR 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 216 GGFNIVAIALGADPGATwRAEssgrQKALLLEQFRGF---SPDIVRLLDSSENPTFWPLYQAGPGRWHNGRdTVLIGDAA 292
Cdd:PRK07588  215 TLFLFIFRAEHDNPPLT-PAE----EKQLLRDQFGDVgweTPDILAALDDVEDLYFDVVSQIRMDRWSRGR-VALVGDAA 288

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1119538114 293 HAMMPFAAQGAAMAIEDAFELAGTMvgsdAAATLPAPQALAAFEALRLPRIekARKRASLNRFA 356
Cdd:PRK07588  289 ACPSLLGGEGSGLAITEAYVLAGEL----ARAGGDHRRAFDAYEKRLRPFI--AGKQAAAAKFL 346
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 6-350 3.17e-14

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 73.13  E-value: 3.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKSLAtl 85
Cdd:pfam01494   4 VLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPRAHGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRR-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  86 lslPVGAVARTRWGAPYGvlhrstlqsaLLQTVTDNPL--------CRLHLGKRIENATADVIAAT-TFRDH-------- 148
Cdd:pfam01494  82 ---RADLDFLTSPPRVTV----------YPQTELEPILvehaeargAQVRFGTEVLSLEQDGDGVTaVVRDRrdgeeytv 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 149 --DLIVGADGVWSAARFAVPaaptATFSGNVAWRFTVaANAVPSAINksaVTAYLGSGGHIVAYPLKEVGGFNIVAIALG 226
Cdd:pfam01494 149 raKYLVGCDGGRSPVRKTLG----IEFEGFEGVPFGS-LDVLFDAPD---LSDPVERAFVHYLIYAPHSRGFMVGPWRSA 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 227 ADPGATWRAESSGRQ------------KALLLEQFrgfspDIVRLLDSSENPTFWPLYQAGPGRWHNGRdTVLIGDAAHA 294
Cdd:pfam01494 221 GRERYYVQVPWDEEVeerpeeftdeelKQRLRSIV-----GIDLALVEILWKSIWGVASRVATRYRKGR-VFLAGDAAHI 294

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1119538114 295 MMPFAAQGAAMAIEDAFELagtmvGSDAAATL---PAPQALAAFEALRLPRIEKARKRA 350
Cdd:pfam01494 295 HPPTGGQGLNTAIQDAFNL-----AWKLAAVLrgqAGESLLDTYSAERLPVAWAVVDFA 348
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 6-341 3.02e-11

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 64.53  E-value: 3.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQ-----ISPNAARILATLGVLPAIEARWTEPVSVELASGK 80
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEATPLPAPADPGFDnrvsaLSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  81 SLATLLSL--------PVGAVARTRWgapygvlhrstLQSALLQTVTDNPLCRLHLGKRIENATADVIAAT-TFRDHD-- 149
Cdd:TIGR01988  82 GSFGALRFdadeigleALGYVVENRV-----------LQQALWERLQELPNVTLLCPARVVELPRHSDHVElTLDDGQql 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 150 ---LIVGADGVWSAAR--FAVPA--------APTATFS-----GNVAW-RFTvaanavpsainKSAVTAYLgsgghivay 210
Cdd:TIGR01988 151 rarLLVGADGANSKVRqlAGIPTtgwdygqsAVVANVKherphQGTAWeRFT-----------PTGPLALL--------- 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 211 PLKEvGGFNIV-------AIALGADPGATWRAEssgrqkalLLEQFRGFSPDIVrllDSSENPTFwPLYQAGPGRWHNGR 283
Cdd:TIGR01988 211 PLPD-NRSSLVwtlppeeAERLLALSDEEFLAE--------LQRAFGSRLGAIT---LVGERHAF-PLSLTHAKRYVAPR 277

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119538114 284 dTVLIGDAAHAMMPFAAQGAAMAIEDAFELAgtMVGSDAAAT---LPAPQALAAFEALRLP 341
Cdd:TIGR01988 278 -LALIGDAAHTIHPLAGQGLNLGLRDVAALA--EVLEDARRRgedIGSLRVLQRYERRRRF 335
PRK06185 PRK06185
FAD-dependent oxidoreductase;
5-365 3.60e-08

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 54.87  E-value: 3.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVS-VELASGKSLA 83
Cdd:PRK06185    8 DCCIVGGGPAGMMLGLLLARAGVDVTVLEKHADFLRDFRGDTVHPSTLELMDELGLLERFLELPHQKVRtLRFEIGGRTV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  84 TLLSLpvgavARTRWGAPYGVLhrsTLQSALLQTVTDN----PLCRLHLGKRI------ENATADVIAATTFRDH----D 149
Cdd:PRK06185   88 TLADF-----SRLPTPYPYIAM---MPQWDFLDFLAEEasayPNFTLRMGAEVtglieeGGRVTGVRARTPDGPGeiraD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 150 LIVGADGVWSAAR------------------FAVPAAPTATFSgnvawrftvaanavpsainksaVTAYLGSGGHIVAYP 211
Cdd:PRK06185  160 LVVGADGRHSRVRalaglevrefgapmdvlwFRLPREPDDPES----------------------LMGRFGPGQGLIMID 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 212 LkevGGFNIVA--IALGADPgatwraessgRQKALLLEQFRG-------FSPDIVRLLDSSENPTFWPLYQAGPGRWHng 282
Cdd:PRK06185  218 R---GDYWQCGyvIPKGGYA----------ALRAAGLEAFRErvaelapELADRVAELKSWDDVKLLDVRVDRLRRWH-- 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 283 RDTVL-IGDAAHAMMPFAAQGAAMAIEDAFELAGtMVGSDAAATLPAPQALAAFEALRLP----------RIEKARKRAS 351
Cdd:PRK06185  283 RPGLLcIGDAAHAMSPVGGVGINLAIQDAVAAAN-ILAEPLRRGRVSDRDLAAVQRRREFptrvtqalqrRIQRRLLAPA 361

                         410
                  ....*....|....*
gi 1119538114 352 LNRF-AYHATGPVRI 365
Cdd:PRK06185  362 LAGRgPLGPPLLLRL 376
PRK07045 PRK07045
putative monooxygenase; Reviewed
 6-341 1.67e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 52.99  E-value: 1.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAG-ELTEVGAGLqISPNAARILATLGVLPAIEARW-TEPVSVELASGKSLA 83
Cdd:PRK07045    8 VLINGSGIAGVALAHLLGARGHSVTVVERAArNRAQNGADL-LKPSGIGVVRAMGLLDDVFAAGgLRRDAMRLYHDKELI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  84 TLLSLpvgavaRTRWGAPYGVLHR-STLQSALLQTVTDNPLCRLHLGKRIENATAD---VIAATTFRDHD-----LIVGA 154
Cdd:PRK07045   87 ASLDY------RSASALGYFILIPcEQLRRLLLAKLDGLPNVRLRFETSIERIERDadgTVTSVTLSDGErvaptVLVGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 155 DGVWSAAR---FAVPAA----PTATFSGNVAWRFTVAANavpsaiNKSAVTAylgSGGHIVAYPLkevgGFNI--VAIAL 225
Cdd:PRK07045  161 DGARSMIRddvLRMPAErvpyATPMAFGTIALTDSVREC------NRLYVDS---NQGLAYFYPI----GDQAtrLVVSF 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 226 GADPGATWRAESSGRQKALLLEQFRG-FSPDIVRLLDSSENPTFWPLYQAGPGRWHNgRDTVLIGDAAHAMMPFAAQGAA 304
Cdd:PRK07045  228 PADEMQGYLADTTRTKLLARLNEFVGdESADAMAAIGAGTAFPLIPLGRMNLDRYHK-RNVVLLGDAAHSIHPITGQGMN 306

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1119538114 305 MAIEDAFELAGTM--VGSDAAATlpaPQALAAFEALRLP 341
Cdd:PRK07045  307 LAIEDAGELGACLdlHLSGQIAL---ADALERFERIRRP 342
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
4-38 4.21e-07

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 51.78  E-value: 4.21e-07
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:COG1148   141 KRALVIGGGIAGMTAALELAEQGYEVYLVEKEPEL 175
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 4-38 5.83e-06

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 47.90  E-value: 5.83e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:COG1232     2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRV 36
PRK05868 PRK05868
FAD-binding protein;
3-317 7.49e-06

FAD-binding protein;


Pssm-ID: 180297 [Multi-domain]  Cd Length: 372  Bit Score: 47.67  E-value: 7.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   3 IKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTepvsvelasGKSL 82
Cdd:PRK05868    1 MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRGPALDVLERMGLLAAAQEHKT---------RIRG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  83 ATLLSLPVGAVARTRWGAPYGvlhrSTLQSALLQTVTDNpLCRLHLGK---RIENATADVIAA---------TTF----- 145
Cdd:PRK05868   72 ASFVDRDGNELFRDTESTPTG----GPVNSPDIELLRDD-LVELLYGAtqpSVEYLFDDSISTlqddgdsvrVTFeraaa 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 146 RDHDLIVGADGVWSAARFAVpAAPTATFS---GNVAWRFTV-----------------AANAVPSAINKSAVTAYLgsgg 205
Cdd:PRK05868  147 REFDLVIGADGLHSNVRRLV-FGPEEQFVkrlGTHAAIFTVpnfleldywqtwhygdsTMAGVYSARNNTEARAAL---- 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 206 hivayplkevgGFNIVAIALG-ADPGATW-----RAESSGRQKALLLEQFRGfSPDIVrlldssenptFWPLYQAGPGRW 279
Cdd:PRK05868  222 -----------AFMDTELRIDyRDTEAQFaelqrRMAEDGWVRAQLLHYMRS-APDFY----------FDEMSQILMDRW 279

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1119538114 280 HNGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTM 317
Cdd:PRK05868  280 SRGR-VALVGDAGYCCSPLSGQGTSVALLGAYILAGEL 316
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
266-367 1.36e-05

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 46.82  E-value: 1.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 266 PTFWPLYQAGPGRWHNGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGtmVGSDAAATLPAPQALAAFEALRLPRIeK 345
Cdd:PRK07494  264 RQAWPLSGQVAHRFAAGR-TALVGEAAHVFPPIGAQGLNLGLRDVATLVE--IVEDRPEDPGSAAVLAAYDRARRPDI-L 339

                          90       100
                  ....*....|....*....|....
gi 1119538114 346 ARKRA--SLNRFAYHATGPVRIAR 367
Cdd:PRK07494  340 SRTASvdLLNRSLLSDFLPVQDLR 363
PRK06126 PRK06126
hypothetical protein; Provisional
 5-341 4.61e-05

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 45.37  E-value: 4.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDIIEQageltevGAGLQISPNA----ARI---LATLGVLPAIEARwtePVSVELA 77
Cdd:PRK06126    9 PVLIVGGGPVGLALALDLGRRGVDSILVER-------KDGTAFNPKAnttsARSmehFRRLGIADEVRSA---GLPVDYP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  78 ---------SGKSLATLLSLPVGAVAR------TRWGAPYGVlHRST---LQSALLQTVTDNPLCRLHLGKRI------- 132
Cdd:PRK06126   79 tdiayftrlTGYELARFRLPSAREAITpvggpdGSWPSPELP-HRIPqkyLEPILLEHAAAQPGVTLRYGHRLtdfeqda 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 133 ENATADVI---AATTFRDH-DLIVGADGvwsaARFAVPAAPTATFSGNVAWRFTVA----ANAVPSAINKSAVTAYLGSG 204
Cdd:PRK06126  158 DGVTATVEdldGGESLTIRaDYLVGCDG----ARSAVRRSLGISYEGTSGLQRDLSiyirAPGLAALVGHDPAWMYWLFN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 205 ----GHIVAYPLKEVGGFNIVAialgadPGATWRAESSGRQKALLleqFRGFSPDIVRLLDSSENptfWPLYQAGPGRWH 280
Cdd:PRK06126  234 pdrrGVLVAIDGRDEWLFHQLR------GGEDEFTIDDVDARAFV---RRGVGEDIDYEVLSVVP---WTGRRLVADSYR 301

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1119538114 281 NGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMvgsdaAATL---PAPQALAAFEALRLP 341
Cdd:PRK06126  302 RGR-VFLAGDAAHLFTPTGGYGMNTGIGDAVNLAWKL-----AAVLngwAGPALLDSYEAERRP 359
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-33 5.43e-05

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 44.87  E-value: 5.43e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIE 33
Cdd:COG3380     1 MSMPDIAIIGAGIAGLAAARALQDAGHEVTVFE 33
PRK07233 PRK07233
hypothetical protein; Provisional
 6-38 6.18e-05

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 44.88  E-value: 6.18e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:PRK07233    2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQL 34
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-38 6.28e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 44.85  E-value: 6.28e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:COG2072     4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDV 41
PRK07208 PRK07208
hypothetical protein; Provisional
 1-34 7.76e-05

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 44.49  E-value: 7.76e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQ 34
Cdd:PRK07208    2 TNKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEA 35
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
6-314 1.16e-04

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 44.13  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEPVSVELASGKsLATL 85
Cdd:PRK06183   13 VVIVGAGPVGLTLANLLGQYGVRVLVLERWPTLYDLPRAVGIDDEALRVLQAIGLADEVLPHTTPNHGMRFLDAK-GRCL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  86 LSLPVGAVARTRWGAPYGvLHRSTLQSALLQTVTDNPLCRLHLGKRIENATADVIAAT-TFRDHD---------LIVGAD 155
Cdd:PRK06183   92 AEIARPSTGEFGWPRRNA-FHQPLLEAVLRAGLARFPHVRVRFGHEVTALTQDDDGVTvTLTDADgqretvrarYVVGCD 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 156 GVWSAARFAVPAAPTATFSGNvawRFTVAANAVPSAINksavtayLGSGGHIVAYPLKEVggfniVAIALGAD------- 228
Cdd:PRK06183  171 GANSFVRRTLGVPFEDLTFPE---RWLVVDVLIANDPL-------GGPHTYQYCDPARPY-----TSVRLPHGrrrwefm 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 229 --PGAT---WRAESSGRQkalLLEQFrGFSPDIVRLLDSSENpTFwplyQAG-PGRWHNGRdTVLIGDAAHAMMPFAAQG 302
Cdd:PRK06183  236 llPGETeeqLASPENVWR---LLAPW-GPTPDDAELIRHAVY-TF----HARvADRWRSGR-VLLAGDAAHLMPPFAGQG 305

                         330
                  ....*....|..
gi 1119538114 303 AAMAIEDAFELA 314
Cdd:PRK06183  306 MNSGIRDAANLA 317
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
6-32 1.53e-04

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 43.63  E-value: 1.53e-04
                          10        20
                  ....*....|....*....|....*..
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDII 32
Cdd:COG3075     5 VVVIGGGLAGLTAAIRAAEAGLRVAIV 31
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
4-33 1.54e-04

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 43.76  E-value: 1.54e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIE 33
Cdd:COG1231     8 KDVVIVGAGLAGLAAARELRKAGLDVTVLE 37
PRK08255 PRK08255
bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;
277-355 2.92e-04

bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;


Pssm-ID: 236203 [Multi-domain]  Cd Length: 765  Bit Score: 43.00  E-value: 2.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 277 GRWH--NGR-DTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMvgsdAAATLPAPQALAAFEALRLP---RIEKArKRA 350
Cdd:PRK08255  260 ERWVhwNRRvPVVLMGDAAHTAHFSIGSGTKLALEDAIELARCL----HEHPGDLPAALAAYEEERRVevlRIQNA-ARN 334


                  ....*
gi 1119538114 351 SLNRF 355
Cdd:PRK08255  335 STEWF 339
PRK06184 PRK06184
hypothetical protein; Provisional
 6-66 3.20e-04

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 42.66  E-value: 3.20e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEA 66
Cdd:PRK06184    6 VLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVA 66
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 4-33 3.74e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 42.43  E-value: 3.74e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIE 33
Cdd:COG0493   122 KKVAVVGSGPAGLAAAYQLARAGHEVTVFE 151
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
11-338 4.11e-04

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 41.88  E-value: 4.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  11 AGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQISPNAARILATLGVLPAIEARWTEpVSVELASGKSLATLLSLPV 90
Cdd:COG0644     1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKICGGGLLPRALEELEPLGLDEPLERPVRG-ARFYSPGGKSVELPPGRGG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114  91 GAvartrwgapygVLHRSTLQSALLQTVTDNPlCRLHLGKR-----IENATADVIAATTFRDH-DLIVGADGVWS-AARF 163
Cdd:COG0644    80 GY-----------VVDRARFDRWLAEQAEEAG-AEVRTGTRvtdvlRDDGRVVVRTGDGEEIRaDYVVDADGARSlLARK 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 164 AVPAAPTATFSGNVAWRFTVAANAVPSAINKSAVTAYLGSGGHIV---AYPLKEvggfNIVAIALgadpgatwraessgr 240
Cdd:COG0644   148 LGLKRRSDEPQDYALAIKEHWELPPLEGVDPGAVEFFFGEGAPGGygwVFPLGD----GRVSVGI--------------- 208

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 241 qkallleQFRGFSPDIVRlldssenptfwplyqagpGRWhngrdtVLIGDAAHAMMPFAAQGAAMAIEDAfELAGTMVGS 320
Cdd:COG0644   209 -------PLGGPRPRLVG------------------DGV------LLVGDAAGFVDPLTGEGIHLAMKSG-RLAAEAIAE 256

                         330
                  ....*....|....*...
gi 1119538114 321 DAAATLPAPQALAAFEAL 338
Cdd:COG0644   257 ALEGGDFSAEALAEYERR 274
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-38 4.30e-04

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 42.14  E-value: 4.30e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:COG1233     1 MMMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-38 4.39e-04

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 42.15  E-value: 4.39e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1119538114   1 MPIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:COG3349     1 MMPPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRL 38
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 6-38 7.00e-04

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 41.50  E-value: 7.00e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:pfam00890   2 VLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPF 34
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
6-41 8.41e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 40.87  E-value: 8.41e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIE------QAGELTEV 41
Cdd:COG0492     3 VVIIGAGPAGLTAAIYAARAGLKTLVIEggepggQLATTKEI 44
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 4-33 8.48e-04

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 41.32  E-value: 8.48e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIE 33
Cdd:PRK11749  141 KKVAVIGAGPAGLTAAHRLARKGYDVTIFE 170
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 4-43 8.55e-04

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 41.37  E-value: 8.55e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHG--IDCDIIE-------------QAGELTEVGA 43
Cdd:PRK11883    1 KKVAIIGGGITGLSAAYRLHKKGpdADITLLEasdrlggkiqtvrKDGFPIELGP 55
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 6-38 9.59e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 40.84  E-value: 9.59e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLERGDDP 34
glycerol3P_GlpB TIGR03378
glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are ...
 6-34 1.01e-03

glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are the B subunit, product of the glpB gene, of a three-subunit, membrane-anchored, FAD-dependent anaerobic glycerol-3-phosphate dehydrogenase. [Energy metabolism, Anaerobic]


Pssm-ID: 213807  Cd Length: 419  Bit Score: 41.16  E-value: 1.01e-03
                          10        20
                  ....*....|....*....|....*....
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQ 34
Cdd:TIGR03378   3 VIIIGGGLAGLSCALRLAEAGKKCAIIAA 31
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-38 1.11e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 37.13  E-value: 1.11e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1119538114   8 IIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRL 31
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
6-36 1.44e-03

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 40.27  E-value: 1.44e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAG 36
Cdd:COG0665     5 VVVIGGGIAGLSTAYHLARRGLDVTVLERGR 35
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 4-73 1.56e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.99  E-value: 1.56e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQIS-PNAARILATLGVLPAIEARWTEPVS 73
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDEGTCPYGGCVLSKAlLGAAEAPEIASLWADLYKRKEEVVK 71
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
6-32 1.77e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 40.22  E-value: 1.77e-03
                          10        20
                  ....*....|....*....|....*..
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDII 32
Cdd:PRK05329    5 VLVIGGGLAGLTAALAAAEAGKRVALV 31
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 6-35 1.79e-03

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 40.20  E-value: 1.79e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQA 35
Cdd:COG1053     6 VVVVGSGGAGLRAALEAAEAGLKVLVLEKV 35
PRK08401 PRK08401
L-aspartate oxidase; Provisional
 5-32 1.91e-03

L-aspartate oxidase; Provisional


Pssm-ID: 236259 [Multi-domain]  Cd Length: 466  Bit Score: 40.17  E-value: 1.91e-03
                          10        20
                  ....*....|....*....|....*...
gi 1119538114   5 SVAIIGAGIAGLTAALSFARHGIDCDII 32
Cdd:PRK08401    3 KVGIVGGGLAGLTAAISLAKKGFDVTII 30
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
287-369 2.17e-03

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 39.96  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1119538114 287 LIGDAAHAMMPFAAQGAAMAIEDAFELAGTMVGSD-------AAATLPAPQALAAFEALRLpriekARKRASLNRFAYHA 359
Cdd:PRK07333  284 LVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAArlgldigSLDVLERYQRWRRFDTVRM-----GVTTDVLNRLFSND 358

                          90
                  ....*....|
gi 1119538114 360 TGPVRIARDF 369
Cdd:PRK07333  359 STLLRSVRDI 368
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 6-34 2.22e-03

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 39.78  E-value: 2.22e-03
                          10        20
                  ....*....|....*....|....*....
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQ 34
Cdd:PRK08243    5 VAIIGAGPAGLLLGQLLHLAGIDSVVLER 33
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
281-339 2.61e-03

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 39.67  E-value: 2.61e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1119538114 281 NGRdTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMvgsdaAATLPAPQALAAFEALR 339
Cdd:PRK06996  290 NGR-IAAVGNAAQTLHPVAGQGLNLGLRDAHTLADAL-----SDHGATPLALATFAARR 342
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 2-38 3.48e-03

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 39.44  E-value: 3.48e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1119538114   2 PIKSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:PRK01747  259 KARDAAIIGGGIAGAALALALARRGWQVTLYEADEAP 295
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
2-45 3.48e-03

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 39.17  E-value: 3.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1119538114   2 PIKSVAIIGAGIAGLTAALSFARH---GIDCDIIEQAGELtevGAGL 45
Cdd:COG4529     4 ARKRIAIIGGGASGTALAIHLLRRapePLRITLFEPRPEL---GRGV 47
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 4-38 3.84e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 39.47  E-value: 3.84e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIEQAGEL 38
Cdd:PRK12771  138 KRVAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKL 172
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-19 4.03e-03

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 38.94  E-value: 4.03e-03
                          10
                  ....*....|....*....
gi 1119538114   1 MPIKSVAIIGAGIAGLTAA 19
Cdd:COG2907     1 MARMRIAVIGSGISGLTAA 19
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 6-26 4.57e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 38.93  E-value: 4.57e-03
                          10        20
                  ....*....|....*....|.
gi 1119538114   6 VAIIGAGIAGLTAALSFARHG 26
Cdd:COG0029     7 VLVIGSGIAGLSAALKLAERG 27
PRK07364 PRK07364
FAD-dependent hydroxylase;
6-64 6.65e-03

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 38.46  E-value: 6.65e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEqAGELTEVGAGLQ---ISPNAARILATLGVLPAI 64
Cdd:PRK07364   21 VAIVGGGIVGLTLAAALKDSGLRIALIE-AQPAEAAAAKGQayaLSLLSARIFEGIGVWEKI 81
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
6-72 7.88e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 38.01  E-value: 7.88e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1119538114   6 VAIIGAGIAGLTAALSFARHGIDCDIIEQAGELTEVGAGLQ-----ISPNAARILATLGVLPAIEARWTEPV 72
Cdd:PRK07608    8 VVVVGGGLVGASLALALAQSGLRVALLAPRAPPRPADDAWDsrvyaISPSSQAFLERLGVWQALDAARLAPV 79
PRK12831 PRK12831
putative oxidoreductase; Provisional
 4-33 8.61e-03

putative oxidoreductase; Provisional


Pssm-ID: 183780 [Multi-domain]  Cd Length: 464  Bit Score: 38.08  E-value: 8.61e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1119538114   4 KSVAIIGAGIAGLTAALSFARHGIDCDIIE 33
Cdd:PRK12831  141 KKVAVIGSGPAGLTCAGDLAKMGYDVTIFE 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH