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Conserved domains on  [gi|1121123362|ref|WP_073517560|]
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MULTISPECIES: DUF1232 domain-containing protein [Bacillus cereus group]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YkvA COG3339
Uncharacterized membrane protein YkvA, DUF1232 family [Function unknown];
136-213 3.33e-16

Uncharacterized membrane protein YkvA, DUF1232 family [Function unknown];


:

Pssm-ID: 442568  Cd Length: 104  Bit Score: 71.14  E-value: 3.33e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1121123362 136 FLEKIQKVSSIGPFINDLKELYERFTKKKGTTAELALMGSALIYFILSVDVIPDYIFPIGYLDDAVAVQLVLNALMKR 213
Cdd:COG3339     7 WDGKLKKLARRLPFLRRLLLLYYAGRDPRVPWKAKLLIAAALAYFVSPIDLIPDFIPVLGYLDDLAVLALALALVIKE 84
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
24-69 7.81e-07

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 45.37  E-value: 7.81e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDLF 69
Cdd:COG1396    22 TQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELL 67
 
Name Accession Description Interval E-value
YkvA COG3339
Uncharacterized membrane protein YkvA, DUF1232 family [Function unknown];
136-213 3.33e-16

Uncharacterized membrane protein YkvA, DUF1232 family [Function unknown];


Pssm-ID: 442568  Cd Length: 104  Bit Score: 71.14  E-value: 3.33e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1121123362 136 FLEKIQKVSSIGPFINDLKELYERFTKKKGTTAELALMGSALIYFILSVDVIPDYIFPIGYLDDAVAVQLVLNALMKR 213
Cdd:COG3339     7 WDGKLKKLARRLPFLRRLLLLYYAGRDPRVPWKAKLLIAAALAYFVSPIDLIPDFIPVLGYLDDLAVLALALALVIKE 84
DUF1232 pfam06803
Protein of unknown function (DUF1232); This family represents a conserved region of ...
 170-203 8.97e-11

Protein of unknown function (DUF1232); This family represents a conserved region of approximately 60 residues within a number of hypothetical bacterial and archaeal proteins of unknown function.


Pssm-ID: 462011  Cd Length: 36  Bit Score: 54.65  E-value: 8.97e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1121123362 170 LALMGSALIYFILSVDVIPDYIFPIGYLDDAVAV 203
Cdd:pfam06803   1 KLLILGALAYLISPIDLIPDFIPVLGYLDDLAVL 34
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
24-69 7.81e-07

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 45.37  E-value: 7.81e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDLF 69
Cdd:COG1396    22 TQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELL 67
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
24-68 2.23e-06

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 43.28  E-value: 2.23e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1121123362   24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDL 68
Cdd:smart00530  12 TQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 24-68 2.27e-05

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 40.61  E-value: 2.27e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDL 68
Cdd:cd00093    14 TQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 24-68 1.15e-04

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 38.68  E-value: 1.15e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDL 68
Cdd:pfam01381  11 SQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
 
Name Accession Description Interval E-value
YkvA COG3339
Uncharacterized membrane protein YkvA, DUF1232 family [Function unknown];
136-213 3.33e-16

Uncharacterized membrane protein YkvA, DUF1232 family [Function unknown];


Pssm-ID: 442568  Cd Length: 104  Bit Score: 71.14  E-value: 3.33e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1121123362 136 FLEKIQKVSSIGPFINDLKELYERFTKKKGTTAELALMGSALIYFILSVDVIPDYIFPIGYLDDAVAVQLVLNALMKR 213
Cdd:COG3339     7 WDGKLKKLARRLPFLRRLLLLYYAGRDPRVPWKAKLLIAAALAYFVSPIDLIPDFIPVLGYLDDLAVLALALALVIKE 84
DUF1232 pfam06803
Protein of unknown function (DUF1232); This family represents a conserved region of ...
 170-203 8.97e-11

Protein of unknown function (DUF1232); This family represents a conserved region of approximately 60 residues within a number of hypothetical bacterial and archaeal proteins of unknown function.


Pssm-ID: 462011  Cd Length: 36  Bit Score: 54.65  E-value: 8.97e-11
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1121123362 170 LALMGSALIYFILSVDVIPDYIFPIGYLDDAVAV 203
Cdd:pfam06803   1 KLLILGALAYLISPIDLIPDFIPVLGYLDDLAVL 34
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
24-69 7.81e-07

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 45.37  E-value: 7.81e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDLF 69
Cdd:COG1396    22 TQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELL 67
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
24-68 2.23e-06

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 43.28  E-value: 2.23e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1121123362   24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDL 68
Cdd:smart00530  12 TQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 24-68 2.27e-05

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 40.61  E-value: 2.27e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDL 68
Cdd:cd00093    14 TQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 24-68 1.15e-04

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 38.68  E-value: 1.15e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDL 68
Cdd:pfam01381  11 SQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
24-69 2.51e-04

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 38.29  E-value: 2.51e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1121123362  24 SMRKLSSLTDIDTATISMIVNGKRKANPKHLQKFAESLDVPVGDLF 69
Cdd:COG1476    19 TQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELF 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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