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Conserved domains on  [gi|1124302339|ref|WP_074595998|]
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MULTISPECIES: VanZ family protein [Bacillus]

Protein Classification

VanZ family protein( domain architecture ID 10008822)

VanZ family protein is an integral membrane protein similar to Enterococcus faecium protein VanZ, which confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te)

Gene Ontology:  GO:0046677|GO:0071555|GO:0005576

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VanZ COG4767
Glycopeptide antibiotics resistance protein [Defense mechanisms];
90-157 2.39e-21

Glycopeptide antibiotics resistance protein [Defense mechanisms];


:

Pssm-ID: 443799  Cd Length: 91  Bit Score: 84.11  E-value: 2.39e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1124302339  90 YLLNIVLFMPFGFLLPTIWPQFRKMKNTVCAGFLFSLAIELNQL-LNNRITDIDDLFTNTLGAIVGYVL 157
Cdd:COG4767    23 ILGNILLFVPLGFLLPLLFKRLRSFKRVLLLGFLLSLLIEVLQLiLPGRVFDIDDLILNTLGALLGYLL 91
 
Name Accession Description Interval E-value
VanZ COG4767
Glycopeptide antibiotics resistance protein [Defense mechanisms];
90-157 2.39e-21

Glycopeptide antibiotics resistance protein [Defense mechanisms];


Pssm-ID: 443799  Cd Length: 91  Bit Score: 84.11  E-value: 2.39e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1124302339  90 YLLNIVLFMPFGFLLPTIWPQFRKMKNTVCAGFLFSLAIELNQL-LNNRITDIDDLFTNTLGAIVGYVL 157
Cdd:COG4767    23 ILGNILLFVPLGFLLPLLFKRLRSFKRVLLLGFLLSLLIEVLQLiLPGRVFDIDDLILNTLGALLGYLL 91
VanZ pfam04892
VanZ like family; This family contains several examples of the VanZ protein, but also contains ...
 90-160 9.54e-15

VanZ like family; This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.


Pssm-ID: 461467  Cd Length: 79  Bit Score: 66.73  E-value: 9.54e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1124302339  90 YLLNIVLFMPFGFLLPTIWPqfRKMKNTVCAGFLFSLAIELNQLL-NNRITDIDDLFTNTLGAIVGYVLYKV 160
Cdd:pfam04892  10 YVRNIAHFVPFGFLLPLLFK--RRFLKTLLLGFLYSLSDELHQLFvPGRSFDVDDVILNTLGALIGILLYLL 79
 
Name Accession Description Interval E-value
VanZ COG4767
Glycopeptide antibiotics resistance protein [Defense mechanisms];
90-157 2.39e-21

Glycopeptide antibiotics resistance protein [Defense mechanisms];


Pssm-ID: 443799  Cd Length: 91  Bit Score: 84.11  E-value: 2.39e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1124302339  90 YLLNIVLFMPFGFLLPTIWPQFRKMKNTVCAGFLFSLAIELNQL-LNNRITDIDDLFTNTLGAIVGYVL 157
Cdd:COG4767    23 ILGNILLFVPLGFLLPLLFKRLRSFKRVLLLGFLLSLLIEVLQLiLPGRVFDIDDLILNTLGALLGYLL 91
VanZ pfam04892
VanZ like family; This family contains several examples of the VanZ protein, but also contains ...
 90-160 9.54e-15

VanZ like family; This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.


Pssm-ID: 461467  Cd Length: 79  Bit Score: 66.73  E-value: 9.54e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1124302339  90 YLLNIVLFMPFGFLLPTIWPqfRKMKNTVCAGFLFSLAIELNQLL-NNRITDIDDLFTNTLGAIVGYVLYKV 160
Cdd:pfam04892  10 YVRNIAHFVPFGFLLPLLFK--RRFLKTLLLGFLYSLSDELHQLFvPGRSFDVDDVILNTLGALIGILLYLL 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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