|
Name |
Accession |
Description |
Interval |
E-value |
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1040 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1209.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 3 FSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 83 QStNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAAL 162
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 163 NVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALgappsdAGNSFQLSINTQGR 242
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 243 LVTEEEFENIIIRaGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQ 322
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 323 GMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLV 402
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 403 LAIGIVVDDAIVVVENVERNIGL-GKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTV 481
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 482 ISAFNSLTLSPALAAVLLKDHHAPKDrfsrlldrlfgGWLFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLGG 561
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH-----------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 562 YLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSINGFTNSPNSGIVFTPLK 641
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLK 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 642 PFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVED-RGGLGYEELYKQTQNIIAKARQLPE 720
Cdd:pfam00873 622 PWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 721 LNpmSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLK 800
Cdd:pfam00873 702 LS--DVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLY 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 801 VRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKE-ELPNGMTYEWTDLTYQQIL 879
Cdd:pfam00873 780 VRNPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvKLPPGYGYTWTGQFEQEQL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 880 AGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEF 959
Cdd:pfam00873 860 AGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEF 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 960 AKEKQE-EGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVL 1038
Cdd:pfam00873 940 ANELREqEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVL 1019
|
..
gi 1124693201 1039 IR 1040
Cdd:pfam00873 1020 FH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1045 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1162.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 1 MNFSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 81 SSQSTnDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDqrYDMLYLSNYA 160
Cdd:COG0841 81 TSTSS-EGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 161 ALNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGappsdaGNSFQLSINTQ 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 241 GRLVTEEEFENIIIRAgDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGF 320
Cdd:COG0841 232 GRLKTPEEFENIVIRT-NDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 321 PQGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFG 400
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 401 LVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAIST 480
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 481 VISAFNSLTLSPALAAVLLKDHHAPKDrfsrlldrlfgGWLFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLG 560
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKK-----------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 561 GYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSinGFTNSPNSGIVFTPL 640
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFS--GGGSGSNSGTIFVTL 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 641 KPFDERKdpsMSAGAIAAALNQEFAGIQDAYIAIFPPPPvQGLGTIGGFRLQVEdrgGLGYEELYKQTQNIIAKARQLPE 720
Cdd:COG0841 618 KPWDERD---RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 721 LnpMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLK 800
Cdd:COG0841 691 L--VDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLY 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 801 VRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKEE-LPNGMTYEWTDLTYQQIL 879
Cdd:COG0841 769 VRTPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELkLPPGVSIEFTGQAEEEQE 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 880 AGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEF 959
Cdd:COG0841 849 SFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDF 928
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 960 AKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI 1039
Cdd:COG0841 929 ANQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLL 1008
|
....*.
gi 1124693201 1040 RGFVEK 1045
Cdd:COG0841 1009 DRLRRR 1014
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1056 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1043.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 3 FSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 83 QSTNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAAL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 163 NVKDELARLDGVGDVQLFGmGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPSDAGNSFQLSINTQGR 242
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFG-SQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 243 LVTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQ 322
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 323 GMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLV 402
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 403 LAIGIVVDDAIVVVENVERNI-GLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTV 481
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 482 ISAFNSLTLSPALAAVLLK-----DHHAPKDRFsrlldrlfggwlFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGG 556
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKpiekgEHHEKKGGF------------FGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 557 LLLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPG--VENTVAFPGLSINGftNSPNSG 634
Cdd:TIGR00915 548 LVGGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanVESVFTVNGFSFAG--RGQNMG 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 635 IVFTPLKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDRGGLGYEELYKQTQNIIAK 714
Cdd:TIGR00915 626 MAFIRLKDWEERTGKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGL 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 715 ARQLPELnpMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPE 794
Cdd:TIGR00915 706 AAQNPAL--TRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPE 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 795 QIGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKeELPNGMTYEWTDLT 874
Cdd:TIGR00915 784 DINKWYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQ-KLPPGFGFSWTGMS 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 875 YQQILAGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAI 954
Cdd:TIGR00915 863 YEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAI 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 955 LIVEFAKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPV 1034
Cdd:TIGR00915 943 LIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPL 1022
|
1050 1060
....*....|....*....|..
gi 1124693201 1035 FYVLIRGFVeKGEARKAAKAQK 1056
Cdd:TIGR00915 1023 FYVVVRRLF-KRKAHEKEMSVE 1043
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
4-1040 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 823.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:PRK15127 2 PNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAALN 163
Cdd:PRK15127 82 SDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 164 VKDELARLDGVGDVQLFGmGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPSDAGNSFQLSINTQGRL 243
Cdd:PRK15127 162 MKDPISRTSGVGDVQLFG-SQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 244 VTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQG 323
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 324 MDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVL 403
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 404 AIGIVVDDAIVVVENVERNIG-LGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTVI 482
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAeEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 483 SAFNSLTLSPALAAVLLK-----DHHAPKDRFsrlldrlfggwlFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGL 557
Cdd:PRK15127 481 SVLVALILTPALCATMLKpiakgDHGEGKKGF------------FGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLII 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 558 LLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSE--IAAKHPGVENTVAFPGLSINGftNSPNSGI 635
Cdd:PRK15127 549 VVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGFAG--RGQNTGI 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 636 VFTPLKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDRGGLGYEELYKQTQNIIAKA 715
Cdd:PRK15127 627 AFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 716 RQLPELnPMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQ 795
Cdd:PRK15127 707 AKHPDM-LVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDD 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 796 IGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKlLKEELPNGMTYEWTDLTY 875
Cdd:PRK15127 786 IGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEE-LASKLPTGVGYDWTGMSY 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 876 QQILAGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAIL 955
Cdd:PRK15127 865 QERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAIL 944
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 956 IVEFAKEKQE-EGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPV 1034
Cdd:PRK15127 945 IVEFAKDLMDkEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPV 1024
|
....*.
gi 1124693201 1035 FYVLIR 1040
Cdd:PRK15127 1025 FFVVVR 1030
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1039 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 735.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNdGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDL-TMVVHLTSpdQRYDMLYLSNYAAL 162
Cdd:NF033617 81 SSL-GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTpIMYIGLTS--EEMPRGQLTDYAER 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 163 NVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPpsdaGNSFQLSINTQgr 242
Cdd:NF033617 158 VLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGD----SVVSTVRANDQ-- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 243 LVTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQ 322
Cdd:NF033617 232 LKTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 323 GMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLV 402
Cdd:NF033617 312 NIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 403 LAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTVI 482
Cdd:NF033617 392 LAIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVII 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 483 SAFNSLTLSPALAAVLLKDHHAPkDRFSRLLDrlfggwlfgpfnRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLGGY 562
Cdd:NF033617 472 SGIVALTLTPMMCSRLLKANEKP-GRFARAVD------------RFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLP 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 563 LGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFpglSINGFTNSPNSGIVFTPLKP 642
Cdd:NF033617 539 LLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSF---NGVGGNPGDNTGFGIINLKP 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 643 FDERKDpsmSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGlGTIGGFRLQVEDRGGLGYEELYKQTQNIIAKARQLPELn 722
Cdd:NF033617 616 WDERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQF- 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 723 pMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLKVR 802
Cdd:NF033617 691 -ADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVR 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 803 NNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKEELPNGMTYEWTDLTYQQILAGN 882
Cdd:NF033617 770 SNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGS 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 883 TAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKE 962
Cdd:NF033617 850 SLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANE 929
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1124693201 963 KQ-EEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI 1039
Cdd:NF033617 930 LQrHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1040 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1209.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 3 FSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 83 QStNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAAL 162
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 163 NVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALgappsdAGNSFQLSINTQGR 242
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 243 LVTEEEFENIIIRaGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQ 322
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 323 GMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLV 402
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 403 LAIGIVVDDAIVVVENVERNIGL-GKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTV 481
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 482 ISAFNSLTLSPALAAVLLKDHHAPKDrfsrlldrlfgGWLFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLGG 561
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH-----------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 562 YLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSINGFTNSPNSGIVFTPLK 641
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLK 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 642 PFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVED-RGGLGYEELYKQTQNIIAKARQLPE 720
Cdd:pfam00873 622 PWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 721 LNpmSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLK 800
Cdd:pfam00873 702 LS--DVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLY 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 801 VRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKE-ELPNGMTYEWTDLTYQQIL 879
Cdd:pfam00873 780 VRNPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvKLPPGYGYTWTGQFEQEQL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 880 AGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEF 959
Cdd:pfam00873 860 AGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEF 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 960 AKEKQE-EGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVL 1038
Cdd:pfam00873 940 ANELREqEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVL 1019
|
..
gi 1124693201 1039 IR 1040
Cdd:pfam00873 1020 FH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1045 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1162.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 1 MNFSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 81 SSQSTnDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDqrYDMLYLSNYA 160
Cdd:COG0841 81 TSTSS-EGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 161 ALNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGappsdaGNSFQLSINTQ 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 241 GRLVTEEEFENIIIRAgDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGF 320
Cdd:COG0841 232 GRLKTPEEFENIVIRT-NDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 321 PQGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFG 400
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 401 LVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAIST 480
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 481 VISAFNSLTLSPALAAVLLKDHHAPKDrfsrlldrlfgGWLFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLG 560
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKK-----------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 561 GYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSinGFTNSPNSGIVFTPL 640
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFS--GGGSGSNSGTIFVTL 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 641 KPFDERKdpsMSAGAIAAALNQEFAGIQDAYIAIFPPPPvQGLGTIGGFRLQVEdrgGLGYEELYKQTQNIIAKARQLPE 720
Cdd:COG0841 618 KPWDERD---RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 721 LnpMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLK 800
Cdd:COG0841 691 L--VDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLY 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 801 VRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKEE-LPNGMTYEWTDLTYQQIL 879
Cdd:COG0841 769 VRTPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELkLPPGVSIEFTGQAEEEQE 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 880 AGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEF 959
Cdd:COG0841 849 SFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDF 928
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 960 AKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI 1039
Cdd:COG0841 929 ANQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLL 1008
|
....*.
gi 1124693201 1040 RGFVEK 1045
Cdd:COG0841 1009 DRLRRR 1014
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1056 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1043.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 3 FSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 83 QSTNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAAL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 163 NVKDELARLDGVGDVQLFGmGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPSDAGNSFQLSINTQGR 242
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFG-SQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 243 LVTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQ 322
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 323 GMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLV 402
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 403 LAIGIVVDDAIVVVENVERNI-GLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTV 481
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 482 ISAFNSLTLSPALAAVLLK-----DHHAPKDRFsrlldrlfggwlFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGG 556
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKpiekgEHHEKKGGF------------FGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 557 LLLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPG--VENTVAFPGLSINGftNSPNSG 634
Cdd:TIGR00915 548 LVGGMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanVESVFTVNGFSFAG--RGQNMG 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 635 IVFTPLKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDRGGLGYEELYKQTQNIIAK 714
Cdd:TIGR00915 626 MAFIRLKDWEERTGKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGL 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 715 ARQLPELnpMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPE 794
Cdd:TIGR00915 706 AAQNPAL--TRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPE 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 795 QIGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKeELPNGMTYEWTDLT 874
Cdd:TIGR00915 784 DINKWYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQ-KLPPGFGFSWTGMS 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 875 YQQILAGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAI 954
Cdd:TIGR00915 863 YEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAI 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 955 LIVEFAKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPV 1034
Cdd:TIGR00915 943 LIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPL 1022
|
1050 1060
....*....|....*....|..
gi 1124693201 1035 FYVLIRGFVeKGEARKAAKAQK 1056
Cdd:TIGR00915 1023 FYVVVRRLF-KRKAHEKEMSVE 1043
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
4-1040 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 823.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:PRK15127 2 PNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAALN 163
Cdd:PRK15127 82 SDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 164 VKDELARLDGVGDVQLFGmGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPSDAGNSFQLSINTQGRL 243
Cdd:PRK15127 162 MKDPISRTSGVGDVQLFG-SQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 244 VTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQG 323
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 324 MDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVL 403
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 404 AIGIVVDDAIVVVENVERNIG-LGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTVI 482
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAeEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 483 SAFNSLTLSPALAAVLLK-----DHHAPKDRFsrlldrlfggwlFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGL 557
Cdd:PRK15127 481 SVLVALILTPALCATMLKpiakgDHGEGKKGF------------FGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLII 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 558 LLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSE--IAAKHPGVENTVAFPGLSINGftNSPNSGI 635
Cdd:PRK15127 549 VVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGFAG--RGQNTGI 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 636 VFTPLKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDRGGLGYEELYKQTQNIIAKA 715
Cdd:PRK15127 627 AFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 716 RQLPELnPMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQ 795
Cdd:PRK15127 707 AKHPDM-LVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDD 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 796 IGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKlLKEELPNGMTYEWTDLTY 875
Cdd:PRK15127 786 IGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEE-LASKLPTGVGYDWTGMSY 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 876 QQILAGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAIL 955
Cdd:PRK15127 865 QERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAIL 944
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 956 IVEFAKEKQE-EGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPV 1034
Cdd:PRK15127 945 IVEFAKDLMDkEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPV 1024
|
....*.
gi 1124693201 1035 FYVLIR 1040
Cdd:PRK15127 1025 FFVVVR 1030
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
4-1040 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 822.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:PRK10555 2 ANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNDGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAALN 163
Cdd:PRK10555 82 SSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 164 VKDELARLDGVGDVQLFGmGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPSDAGNSFQLSINTQGRL 243
Cdd:PRK10555 162 IQDPLSRVNGVGDIDAYG-SQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 244 VTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQG 323
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 324 MDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVL 403
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 404 AIGIVVDDAIVVVENVERNIG-LGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTVI 482
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSeEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 483 SAFNSLTLSPALAAVLLK-----DHHAPKDRFsrlldrlfgGWlfgpFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGL 557
Cdd:PRK10555 481 SVLVAMILTPALCATLLKplkkgEHHGQKGFF---------GW----FNRMFNRNAERYEKGVAKILHRSLRWILIYVLL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 558 LLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSINGFTNSPNSGIVF 637
Cdd:PRK10555 548 LGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMF 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 638 TPLKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDRGGLGYEELYKQTQNIIAKARQ 717
Cdd:PRK10555 628 IRLKDWDERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAK 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 718 LPELNpmSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIG 797
Cdd:PRK10555 708 NPELT--RVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDIN 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 798 QLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLkEELPNGMTYEWTDLTYQQ 877
Cdd:PRK10555 786 LWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLV-KQLPNGFGLEWTAMSYQE 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 878 ILAGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIV 957
Cdd:PRK10555 865 RLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIV 944
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 958 EFAKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYV 1037
Cdd:PRK10555 945 EFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFV 1024
|
...
gi 1124693201 1038 LIR 1040
Cdd:PRK10555 1025 LVR 1027
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
4-1049 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 805.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:PRK09577 2 ARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSAT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNdGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYAALN 163
Cdd:PRK09577 82 SSA-GQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 164 VKDELARLDGVGDVQLFGmGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPSDAGNSFQLSINTQGRL 243
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWG-AEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 244 VTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQG 323
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 324 MDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVL 403
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 404 AIGIVVDDAIVVVENVERNIGL-GKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTVI 482
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEeGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 483 SAFNSLTLSPALAAVLLK---DHHAPKDRFsrlldrlfggwlFGPFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLL 559
Cdd:PRK09577 480 SAFLALSLTPALCATLLKpvdGDHHEKRGF------------FGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTA 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 560 GGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSINGftNSPNSGIVFTP 639
Cdd:PRK09577 548 AAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYG--EGPNGGMIFVT 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 640 LKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDRGGLGYEELYKQTQNIIAKARQLP 719
Cdd:PRK09577 626 LKDWKERKAARDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 720 ELNPMsVFTSYQvNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQL 799
Cdd:PRK09577 706 ALTDL-MFAGTQ-DAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKL 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 800 KVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKeELPNGMTYEWTDLTYQQIL 879
Cdd:PRK09577 784 RVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA-TLPAGIGYAWSGQSFEERL 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 880 AGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEF 959
Cdd:PRK09577 863 SGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEV 942
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 960 AKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI 1039
Cdd:PRK09577 943 AKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
1050
....*....|
gi 1124693201 1040 RGFVEKGEAR 1049
Cdd:PRK09577 1023 GRLFDVGPRR 1032
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1039 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 735.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNdGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGVTVDKASPDL-TMVVHLTSpdQRYDMLYLSNYAAL 162
Cdd:NF033617 81 SSL-GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTpIMYIGLTS--EEMPRGQLTDYAER 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 163 NVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPpsdaGNSFQLSINTQgr 242
Cdd:NF033617 158 VLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGD----SVVSTVRANDQ-- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 243 LVTEEEFENIIIRAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFPQ 322
Cdd:NF033617 232 LKTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 323 GMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLV 402
Cdd:NF033617 312 NIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 403 LAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTVI 482
Cdd:NF033617 392 LAIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVII 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 483 SAFNSLTLSPALAAVLLKDHHAPkDRFSRLLDrlfggwlfgpfnRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLGGY 562
Cdd:NF033617 472 SGIVALTLTPMMCSRLLKANEKP-GRFARAVD------------RFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLP 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 563 LGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFpglSINGFTNSPNSGIVFTPLKP 642
Cdd:NF033617 539 LLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSF---NGVGGNPGDNTGFGIINLKP 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 643 FDERKDpsmSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGlGTIGGFRLQVEDRGGLGYEELYKQTQNIIAKARQLPELn 722
Cdd:NF033617 616 WDERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQF- 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 723 pMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLKVR 802
Cdd:NF033617 691 -ADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVR 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 803 NNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAKLLKEELPNGMTYEWTDLTYQQILAGN 882
Cdd:NF033617 770 SNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGS 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 883 TAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKE 962
Cdd:NF033617 850 SLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANE 929
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1124693201 963 KQ-EEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI 1039
Cdd:NF033617 930 LQrHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1039 |
8.46e-162 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 504.75 E-value: 8.46e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 1 MNFSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 81 SSQSTNDGKlTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQrlGVTVDKASPDLTMVVHLTSPDQRYDMLYLSNYA 160
Cdd:PRK09579 81 TSVSRQNFS-IISIYARIGADSDRLFTELLAKANEVKNQLPQDAE--DPVLSKEAADASALMYISFYSEEMSNPQITDYL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 161 ALNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALgappsdAGNSFQLSINTQ 240
Cdd:PRK09579 158 SRVIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEV------KGEYVVTSINAS 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 241 GRLVTEEEFENIIIRAGDDGEItRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGF 320
Cdd:PRK09579 232 TELKSAEAFAAIPVKTSGDSRV-LLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 321 PQGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFG 400
Cdd:PRK09579 311 PPNLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 401 LVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAIST 480
Cdd:PRK09579 391 MVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAV 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 481 VISAFNSLTLSPALAAVLLKDHHAPKDRFSRLldrlfggwlfgpfNRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLG 560
Cdd:PRK09579 471 IISGIVALTLSPMMCALLLRHEENPSGLAHRL-------------DRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLAL 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 561 GYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPgvENTVAFpglSINGFtNSPNSGIVFTPL 640
Cdd:PRK09579 538 IPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFP--EYYSSF---QINGF-NGVQSGIGGFLL 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 641 KPFDERKDPSMSAGAIAAALNQEFAGIQdayIAIFPPPPVQGLGTIGGFRLQVEDRGglGYEELYKQTQNIIAKARQLPE 720
Cdd:PRK09579 612 KPWNERERTQMELLPLVQAKLEEIPGLQ---IFGFNLPSLPGTGEGLPFQFVINTAN--DYESLLQVAQRVKQRAQESGK 686
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 721 LNPMSVFTSYqvNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNVQADQPFRLEPEQIGQLK 800
Cdd:PRK09579 687 FAFLDIDLAF--DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYY 764
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 801 VRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGaaAPGYSSGQAEDAIAKLLKEELPNGMTYEWTDLTYQQILA 880
Cdd:PRK09579 765 VKNEQGQLLPLSTLITLSDRARPRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQE 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 881 GNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEFA 960
Cdd:PRK09579 843 GSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFA 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 961 KE-KQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI 1039
Cdd:PRK09579 923 NQlRHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLL 1002
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
4-1038 |
1.54e-122 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 401.03 E-value: 1.54e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 4 SQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQ 83
Cdd:PRK10503 13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 84 STNdGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGV--TVDKASPDLtMVVHLTSPDQryDMLYLSNYAA 161
Cdd:PRK10503 93 SSG-GASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVysKVNPADPPI-MTLAVTSTAM--PMTQVEDMVE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 162 LNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAPPsdagNSFQLSINTQG 241
Cdd:PRK10503 169 TRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPT----RAVTLSANDQM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 242 RLVteEEFENIIIrAGDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAELKQGFP 321
Cdd:PRK10503 245 QSA--EEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 322 QGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGL 401
Cdd:PRK10503 322 KSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMAL 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 402 VLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALTIAISTV 481
Cdd:PRK10503 402 TIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAIL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 482 ISAFNSLTLSPALAAVLLKDHHAPK-DRFSRLLDrlfggwlfgpfnRFFDRAGKGYVGTVRRVLRGSSIAMLVYGGLLLG 560
Cdd:PRK10503 482 ISAVVSLTLTPMMCARMLSQESLRKqNRFSRASE------------RMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 561 GYLGFSSTPTGFVPQQDKQYLVAFAQLPD----AATLDRTEAVikrmSEIAAKHPGVENTVAFPGlsINGFTNSPNSGIV 636
Cdd:PRK10503 550 TVLLWIFIPKGFFPVQDNGIIQGTLQAPQsssfANMAQRQRQV----ADVILQDPAVQSLTSFVG--VDGTNPSLNSARL 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 637 FTPLKPFDERKDpsmSAGAIAAALNQEFAGIQDAYIAIfppPPVQGLgTIGG--------FRLQvedrgGLGYEELYKQT 708
Cdd:PRK10503 624 QINLKPLDERDD---RVQKVIARLQTAVAKVPGVDLYL---QPTQDL-TIDTqvsrtqyqFTLQ-----ATSLDALSTWV 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 709 QNIIAKARQLPELNPMSvfTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMqvylgslyandFNRFGRTY--QVNVQAD 786
Cdd:PRK10503 692 PKLMEKLQQLPQLSDVS--SDWQDKGLVAYVNVDRDSASRLGISMADVDNAL-----------YNAFGQRLisTIYTQAN 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 787 QpFRLEPEQ----------IGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAIAK 856
Cdd:PRK10503 759 Q-YRVVLEHntentpglaaLDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMD 837
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 857 LLKE-ELPNGMT--YEWTDLTYQQILaGNTAIFIFPLCVLLaFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSD 933
Cdd:PRK10503 838 TEKTlNLPADITtqFQGSTLAFQSAL-GSTVWLIVAAVVAM-YIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSE 915
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 934 NNIFTQIGLIVLVGLACKNAILIVEFA-KEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHA 1012
Cdd:PRK10503 916 LDVIAIIGIILLIGIVKKNAIMMIDFAlAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRP 995
|
1050 1060
....*....|....*....|....*.
gi 1124693201 1013 MGVAVFSGMIGVTFFGLLLTPVFYVL 1038
Cdd:PRK10503 996 LGICMVGGLIVSQVLTLFTTPVIYLL 1021
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
1-1037 |
2.29e-122 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 399.87 E-value: 2.29e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 1 MNFSQFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQA---IVGVEGM 77
Cdd:PRK10614 1 MKFFALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSlgrIAGVNEM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 78 LYMSSQstndGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQRLGvTVDKASPD--LTMVVHLTSPDQRYDMLY 155
Cdd:PRK10614 81 TSSSSL----GSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSdaPIMILTLTSDTYSQGQLY 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 156 lsNYAALNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALgappSDAGNSFQL 235
Cdd:PRK10614 156 --DFASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAV----EDGTHRWQI 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 236 SINTQgrLVTEEEFENIIIRAgDDGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAE 315
Cdd:PRK10614 230 QTNDE--LKTAAEYQPLIIHY-NNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPE 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 316 LKQGFPQGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNA 395
Cdd:PRK10614 307 LRETIPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNN 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 396 LSLFGLVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIVATALVLCAVFVPTAFISGLTGQFYQQFALT 475
Cdd:PRK10614 387 LSLMALTIATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVT 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 476 IAISTVISAFNSLTLSPALAAVLLKdHHAPKDRfsrllDRLFGgwlfgpFNRFFDRAGKGYVGTVRRVLRGSSIAMLVYG 555
Cdd:PRK10614 467 LSVAIGISLLVSLTLTPMMCAWLLK-SSKPREQ-----KRLRG------FGRMLVALQQGYGRSLKWVLNHTRWVGVVLL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 556 GLLLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPGLSingftnSPNSGI 635
Cdd:PRK10614 535 GTIALNVWLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGS------RVNSGM 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 636 VFTPLKPFDERKDpsmSAGAIAAALNQEFAGIQDAYIAIFpppPVQGLgTIGG--------FRLQVEDRGGLgyeelyKQ 707
Cdd:PRK10614 609 MFITLKPLSERSE---TAQQVIDRLRVKLAKEPGANLFLM---AVQDI-RVGGrqsnasyqYTLLSDDLAAL------RE 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 708 TQNIIAKA-RQLPELnpMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDifdtmqvylgslyANDF--NRFGR------- 777
Cdd:PRK10614 676 WEPKIRKAlAALPEL--ADVNSDQQDKGAEMALTYDRDTMARLGIDVQA-------------ANSLlnNAFGQrqistiy 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 778 ----TYQVNVQADQPFRLEPEQIGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDA 853
Cdd:PRK10614 741 qplnQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAA 820
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 854 IAKLLKE-ELPNGM--TYEWTDLTYQQILagNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPtvlfSAIVGVILA 930
Cdd:PRK10614 821 IERAMTQlGVPSTVrgSFAGTAQVFQETM--NSQLILILAAIATVYIVLGILYESYVHPLTILSTLP----SAGVGALLA 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 931 ----GSDNNIFTQIGLIVLVGLACKNAILIVEFAKEKQEEG-LDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGA 1005
Cdd:PRK10614 895 lelfNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGnLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGD 974
|
1050 1060 1070
....*....|....*....|....*....|..
gi 1124693201 1006 GAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYV 1037
Cdd:PRK10614 975 GAELRQPLGITIVGGLVMSQLLTLYTTPVVYL 1006
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
5-1049 |
3.80e-116 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 383.22 E-value: 3.80e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 5 QFFIKRPIFAAVLSLLILIGGAISLFQLPI--------------SEYpevvpptvvvranfPGANPKVIGETVASPLEQA 70
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIdafpditnvqvqviTEA--------------PGLSPEEVEQQVTYPIETA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 71 IVGVEGMLYMSSQSTNdGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQ-RLGvtvdkasPDLT------MVVh 143
Cdd:COG3696 73 LNGLPGVKEVRSISRF-GLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTpELG-------PISTglgeiyQYT- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 144 LTSPDQRYDMLYLSNYAALNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALg 223
Cdd:COG3696 144 LESDPGKYSLMELRTLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYI- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 224 appsDAGNSfQLSINTQGRLVTEEEFENIIIRAgDDGEITRLRDIARVELGSnqyALR----SLLNNQPAVAIPVFQRPG 299
Cdd:COG3696 223 ----ERGGQ-EYLVRGIGLIRSLEDIENIVVKT-RNGTPVLLRDVAEVRIGP---APRrgaaTLNGEGEVVGGIVLMLKG 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 300 SNAIAISDAVRQRMAELKQGFPQGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSL 379
Cdd:COG3696 294 ENALEVIEAVKAKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSL 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 380 IGTFAVMHLFGFSLNALSLFGLVLAIGIVVDDAIVVVENVERNIGL------GKSPVEATRQAMKEVTGPIVATALVLCA 453
Cdd:COG3696 374 LFAFIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEEnraagtPRERLEVVLEAAREVRRPIFFATLIIIL 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 454 VFVPTAFISGLTGQFYQQFALTIAISTVISAFNSLTLSPALAAVLLKDHHAPKDrfsrlldrlfggwlfGPFNRFFDRag 533
Cdd:COG3696 454 VFLPIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKE---------------NPLVRWLKR-- 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 534 kGYVGTVRRVLRGSSIAMLVYGGLLLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGV 613
Cdd:COG3696 517 -LYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEV 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 614 ENTVAFPGLSINGF-TNSPNSGIVFTPLKPFDERKDPsMSAGAIAAALNQEFAGIQDAYIAIfppppVQGLGT-----IG 687
Cdd:COG3696 596 ESVVSRTGRAEDATdPMGVNMSETFVILKPRSEWRSG-RTKEELIAEMREALEQIPGVNFNF-----SQPIQMrvdelLS 669
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 688 GFRLQV------EDrgglgYEELYKQTQNIIAKARQLPELnpMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQ 761
Cdd:COG3696 670 GVRADVavkifgDD-----LDVLRRLAEQIEAVLKTVPGA--ADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVE 742
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 762 VYLG-----SLYANDfnrfgRTYQVNVQADQPFRLEPEQIGQLKVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNG----F 832
Cdd:COG3696 743 TAIGgkavgQVYEGE-----RRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGrrriV 817
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 833 ITAEINGAAAPGYssgqAEDAIAKLLKE-ELPNGMTYEWTDlTYQ-QILAGNTAIFIFPLCVLLAFLVLAAQYESWSLPL 910
Cdd:COG3696 818 VQANVRGRDLGSF----VAEAQAKVAEQvKLPPGYYIEWGG-QFEnLQRATARLAIVVPLALLLIFLLLYLAFGSVRDAL 892
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 911 AVILIVPtvlFSAIVGVI---LAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKEKQEEGLDRLAAVLEACRLRLRPILM 987
Cdd:COG3696 893 LILLNVP---FALIGGVLalwLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLM 969
|
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1124693201 988 TSIAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLIRGFVEKGEAR 1049
Cdd:COG3696 970 TALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
5-1055 |
2.26e-82 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 290.12 E-value: 2.26e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 5 QFFIKRPIFAAVLSLLILIGGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETVASPLEQAIVGVEGMLYMSSQS 84
Cdd:TIGR00914 7 SFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 85 TNdGKLTLTVTFALGTDLDNAQVQVQNRVTRTMPTLPTEVQrlgVTVDKASPDLTMVVHLT---------SPDQRYDMLY 155
Cdd:TIGR00914 87 RY-GLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVS---PEMGPISTGLGEIFLYTveaeegarkKDGGAYTLTD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 156 LSNYAALNVKDELARLDGVGDVQLFGMGNYSLRVWLDPNKVASRNLTATDVVNAIREQNRQVAAGALGAppsdagNSFQL 235
Cdd:TIGR00914 163 LRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIER------RGEQY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 236 SINTQGRLVTEEEFENIIIRAGDdGEITRLRDIARVELGSNQYALRSLLNNQPAVAIPVFQRPGSNAIAISDAVRQRMAE 315
Cdd:TIGR00914 237 LVRAPGQVQSMDDIRNIVIATGE-GVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLET 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 316 LKQGFPQGMDYEIVYDPTIFVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNA 395
Cdd:TIGR00914 316 INKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 396 LSLFGlvLAIGIVVDDAIVVVENV-----ERNIGLGKSPVEATR-----QAMKEVTGPIVATALVLCAVFVPTAFISGLT 465
Cdd:TIGR00914 396 MSLGA--LDFGLIVDGAVVIVENAhrrlaEAQHHHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGVE 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 466 GQFYQQFALTIAISTVISAFNSLTLSPALAAVLLKDHHAPKDrfsrlldrlfggwlfgpfNRFFDRAGKGYVGTVRRVLR 545
Cdd:TIGR00914 474 GKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKE------------------NRLMRVLKRRYEPLLERVLA 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 546 GSSIAMLVYGGLLLGGYLGFSSTPTGFVPQQDKQYLVAFAQLPDAATLDRTEAVIKRMSEIAAKHPGVENTVAFPG-LSI 624
Cdd:TIGR00914 536 WPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGtAEI 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 625 NGFTNSPNSGIVFTPLKPFDERKDPSMSAGAIAAALNQEFAGIQDAYIAIFPPPPVQGLGTIGGFRLQVEDR-GGLGYEE 703
Cdd:TIGR00914 616 ATDPMPPNASDTYIILKPESQWPEGKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKvFGDDLDD 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 704 LYKQTQNIIAKARQLPelNPMSVFTSYQVNVPQVDAAIDREKAKTHGVAISDIFDTMQVYLGSLYANDFNRFGRTYQVNV 783
Cdd:TIGR00914 696 LDATAEKISAVLKGVP--GAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVI 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 784 QADQPFRLEPEQIGQL-----KVRNNRGEMIPLSTFVKVDNSSGPDRVMHYNG----FITAEINGAAAPGYSSgQAEDAI 854
Cdd:TIGR00914 774 RLPESLRESPQALRQLpiplpLSEDARKQFIPLSDVADLRVSPGPNQISRENGkrrvVVSANVRGRDLGSFVD-DAKKAI 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 855 AKLLKeeLPNGMTYEWTDlTYQQILAGNTAI-FIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSD 933
Cdd:TIGR00914 853 AEQVK--LPPGYWITWGG-QFEQLQSATKRLqIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIP 929
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 934 NNIFTQIGLIVLVGLACKNAILIVEFAKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSGAGAEMRHAM 1013
Cdd:TIGR00914 930 LSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPL 1009
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|..
gi 1124693201 1014 GVAVFSGMIGVTFFGLLLTPVFYVLIRGFVEKGEARKAAKAQ 1055
Cdd:TIGR00914 1010 ATVVIGGIITATLLTLFVLPALYRLVHRRRHKGRKEHEPLEG 1051
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
361-1047 |
3.71e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 80.29 E-value: 3.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 361 FLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNALS--LFGLVLAIGivvddaivvvenV----------ERNIGLGKS 428
Cdd:COG1033 238 FFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG------------IdygihllnryREERRKGLD 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 429 PVEATRQAMKEVTGPIVATALVlcavfvpTA--FISGLTGQF--YQQFALTIAISTVISAFNSLTLSPALAAVLLKdhha 504
Cdd:COG1033 306 KREALREALRKLGPPVLLTSLT-------TAigFLSLLFSDIppIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPR---- 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 505 PKDRFSRLLDRLFGGWLFGPFNRFFDRAGKGYVGTVrrvlrgssiamlvygglllggylgfsstptgfvpqqdkqyLVAF 584
Cdd:COG1033 375 PKPKTRRLKKPPELGRLLAKLARFVLRRPKVILVVA----------------------------------------LVLA 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 585 AqlpdaatldrteavikrmseiaakhpgventVAFPGLSINGFTNSpnsgivftplkpFDERKDPSMSAGAIAAALNQEF 664
Cdd:COG1033 415 V-------------------------------VSLYGISRLKVEYD------------FEDYLPEDSPIRQDLDFIEENF 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 665 AGIQDAYIAIfppppvqglgtiggfrlQVEDRGGLGYEELYKQTQNIIAKARQLPEL-NPMSVFTSyqvnVPQVDAAIDR 743
Cdd:COG1033 452 GGSDPLEVVV-----------------DTGEPDGLKDPEVLKEIDRLQDYLESLPEVgKVLSLADL----VKELNQALNE 510
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 744 EKAKTHGVAIS-DIFDTMQVYLGSLYANDFNRFgrtyqvnvqadqpfrlepeqigqlkvRNNRGEMIPLSTFVKVDNSSG 822
Cdd:COG1033 511 GDPKYYALPESrELLAQLLLLLSSPPGDDLSRF--------------------------VDEDYSAARVTVRLKDLDSEE 564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 823 PDRVMhyngfitaeingaaapgyssgqaeDAIAKLLKEELPN-GMTYEWTDLTY------QQILAGNtaIFIFPLCVLLA 895
Cdd:COG1033 565 IKALV------------------------EEVRAFLAENFPPdGVEVTLTGSAVlfaainESVIESQ--IRSLLLALLLI 618
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 896 FLVLAAQYESWSLPLavILIVPTVLFSAIVGVI--LAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKEKQEEGLDRLAA 973
Cdd:COG1033 619 FLLLLLAFRSLRLGL--ISLIPNLLPILLTFGLmgLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEA 696
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1124693201 974 VLEACRLRLRPILMTSIAFIMGVVPLVLSSGAG-AEMRHAMGVAVFSGMIGVtffgLLLTPVFYVLIRGFVEKGE 1047
Cdd:COG1033 697 IRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPlADFGLLLALGLLVALLAA----LLLLPALLLLLDPRIAKKR 767
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
879-1054 |
1.32e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 59.10 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 879 LAGNTAIFIFPLCVLLAFLVLAAQYESWSlplAVILIVPTVLFSAIVG---VILAGSDNNIFTQIGLIVLVGLACKNAIL 955
Cdd:COG1033 215 AIQSDLAIFFPLALLLILLLLFLFFRSLR---GVLLPLLVVLLAVIWTlglMGLLGIPLSPLTILVPPLLLAIGIDYGIH 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 956 IVEFAKEKQEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLS-SGAGAEmrhaMGVAVFSGMIGVTFFGLLLTPV 1034
Cdd:COG1033 292 LLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSdIPPIRD----FGIVAAIGVLLAFLTSLTLLPA 367
|
170 180
....*....|....*....|
gi 1124693201 1035 FYVLIRGFVEKGEARKAAKA 1054
Cdd:COG1033 368 LLSLLPRPKPKTRRLKKPPE 387
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
320-495 |
2.54e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 51.76 E-value: 2.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 320 FPQGMDYEIVYDPTI---FVRGSIEAVVHTLLEAIVLVVLVVILFLQTWRASIIPLAAVPVSLIGTFAVMHLFGFSLNAL 396
Cdd:TIGR00921 169 PPSGKFLDVTGSPAInydIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYAT 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 397 SLFGLVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEvTGPIVATALVLCAVFVPTAFISGLtgQFYQQFALTI 476
Cdd:TIGR00921 249 TLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRR-TGRAVLIALLTTSAGFAALALSEF--PMVSEFGLGL 325
|
170
....*....|....*....
gi 1124693201 477 AISTVISAFNSLTLSPALA 495
Cdd:TIGR00921 326 VAGLITAYLLTLLVLPALL 344
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
793-1047 |
1.63e-05 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 49.13 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 793 PEQIGQ--LKVrNNRGEMIPLSTFVKVD-NSSGPDRVMHYNGFITAEINGAAAPGYSSGQAEDAI-AKLLKEE--LPNGM 866
Cdd:PRK15127 243 TEEFGKilLKV-NQDGSRVRLRDVAKIElGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIrAELAKMEpfFPSGL 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 867 T--YEWTDLTYQQIlAGNTAIFIFPLCVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQIGLIV 944
Cdd:PRK15127 322 KivYPYDTTPFVKI-SIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 945 LVGLACKNAILIVE-FAKEKQEEGLdrlaAVLEACRLRLRPI--LMTSIAFIMGVV--PLVLSSGAGAEMRHAMGVAVFS 1019
Cdd:PRK15127 401 AIGLLVDDAIVVVEnVERVMAEEGL----PPKEATRKSMGQIqgALVGIAMVLSAVfvPMAFFGGSTGAIYRQFSITIVS 476
|
250 260
....*....|....*....|....*...
gi 1124693201 1020 GMIGVTFFGLLLTPVFYVLIRGFVEKGE 1047
Cdd:PRK15127 477 AMALSVLVALILTPALCATMLKPIAKGD 504
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
793-1047 |
3.50e-05 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 47.90 E-value: 3.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 793 PEQIGQLKVRNNR-GEMIPLSTFVKVDnsSGPDRVMHYNGFitaeiNGAAAPGYS----SGQAEDAIAKLLKEEL----- 862
Cdd:PRK10555 243 PEQFRDITLRVNQdGSEVTLGDVATVE--LGAEKYDYLSRF-----NGKPASGLGvklaSGANEMATAKLVLNRLdelaq 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 863 --PNGMTYEWTDLTYQQILAGNTAIFIFPL-CVLLAFLVLAAQYESWSLPLAVILIVPTVLFSAIVGVILAGSDNNIFTQ 939
Cdd:PRK10555 316 yfPHGLEYKVAYETTSFVKASIEDVVKTLLeAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTM 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 940 IGLIVLVGLACKNAILIVEFAKE-KQEEGLDRLaavlEACRLRLRPI--LMTSIAFIMGVV--PLVLSSGAGAEMRHAMG 1014
Cdd:PRK10555 396 FAMVLAIGLLVDDAIVVVENVERiMSEEGLTPR----EATRKSMGQIqgALVGIAMVLSAVfvPMAFFGGTTGAIYRQFS 471
|
250 260 270
....*....|....*....|....*....|...
gi 1124693201 1015 VAVFSGMIGVTFFGLLLTPVFYVLIRGFVEKGE 1047
Cdd:PRK10555 472 ITIVSAMVLSVLVAMILTPALCATLLKPLKKGE 504
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
367-545 |
6.48e-05 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 47.07 E-value: 6.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 367 ASIIPLAAVPVSLIGTFAVMHLFG-------FSLNALSLFGLVLAIgivvddaivvvenverNIGL------------GK 427
Cdd:COG2409 195 AALLPLLTAGLAVGVALGLLALLAaftdvssFAPNLLTMLGLGVGI----------------DYALflvsryreelraGE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 428 SPVEATRQAMKEVTGPIVATALvlcAVFVPTA--FISGLTgqFYQQFALTIAISTVISAFNSLTLSPALAAvllkdhhap 505
Cdd:COG2409 259 DREEAVARAVATAGRAVLFSGL---TVAIALLglLLAGLP--FLRSMGPAAAIGVAVAVLAALTLLPALLA--------- 324
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1124693201 506 kdrfsrlldrLFGGWLFGPFNRFFDRAGKGYVGTVRRVLR 545
Cdd:COG2409 325 ----------LLGRRVFWPRRPRRRRAAAPESGFWRRLAR 354
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
369-494 |
9.71e-05 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 46.13 E-value: 9.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 369 IIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIV-AT 447
Cdd:TIGR01129 274 LIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFdAN 353
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1124693201 448 ALVLCAVFVPTAFISGLTgqfyQQFALTIAISTVISAFNSLTLSPAL 494
Cdd:TIGR01129 354 ITTLIAALILYVFGTGPV----KGFAVTLAIGIIASLFTALVFTRLL 396
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
367-498 |
1.31e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 42.28 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 367 ASIIPLAAVPVSLIGTFAVM----HLFGFSLNALS---LFGLVLAIGIVVDDAIVVVENVERniGLGKSPVEATRQAMKE 439
Cdd:pfam03176 168 AALLPLLTVGLSLGAAQGLVailaHILGIGLSTFAlnlLVVLLIAVGTDYALFLVSRYREEL--RAGEDREEAVIRAVRG 245
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1124693201 440 VTGPIVATALVLCAVFVPTAFiSGLTgqFYQQFALTIAISTVISAFNSLTLSPALAAVL 498
Cdd:pfam03176 246 TGKVVTAAGLTVAIAMLALSF-ARLP--VFAQVGPTIAIGVLVDVLAALTLLPALLALL 301
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
892-1052 |
3.25e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 41.12 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 892 VLLAFLVLAAQYESwslPLAVILIVPTVLFS--------AIVGVILAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKEK 963
Cdd:pfam03176 152 LVVIFIILLIVYRS---VVAALLPLLTVGLSlgaaqglvAILAHILGIGLSTFALNLLVVLLIAVGTDYALFLVSRYREE 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 964 QEEGLDRLAAVLEACRLRLRPILMTSIAFIMGVVPLVLSSgagAEMRHAMGVAVFSGMIGVTFFGLLLTPVFYVLI--RG 1041
Cdd:pfam03176 229 LRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFAR---LPVFAQVGPTIAIGVLVDVLAALTLLPALLALLgrWG 305
|
170
....*....|.
gi 1124693201 1042 FVEKGEARKAA 1052
Cdd:pfam03176 306 LWPPKRDRTAR 316
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
365-488 |
4.27e-03 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 39.55 E-value: 4.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 365 WRASIIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVLAIGIVVDDAIVVVENVERNI--GLGKSPVEATRQAMKEVTG 442
Cdd:TIGR00916 70 WRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDRIREELrkYKGRTFREAINLGINQTLS 149
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1124693201 443 PIVATALVlcaVFVPTAFISGLTGQFYQQFALTIAISTVISAFNSL 488
Cdd:TIGR00916 150 RIIDTNVT---TLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
369-509 |
4.39e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 41.14 E-value: 4.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1124693201 369 IIPLAAVPVSLIGTFAVMHLFGFSLNALSLFGLVLAIGIVVDDAIVVVENVERNIGLGKSPVEATRQAMKEVTGPIV-AT 447
Cdd:PRK13023 304 VIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVdAN 383
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1124693201 448 ALVLCAVFVPTAFISGLTgqfyQQFALTIAISTVISAFNSLTLSPALAAVLL---KDHHAPKDRF 509
Cdd:PRK13023 384 LTTLIAALVLFLLGSGTV----HGFALTVAIGIGTTLFTTLTFTRLLIAQWVrtaKPKEVPKRRL 444
|
|
| |
