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Conserved domains on  [gi|1126562160|ref|WP_075197651|]
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MULTISPECIES: ABC transporter permease [Cronobacter]

Protein Classification

ABC transporter permease( domain architecture ID 11487570)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs; similar to microcin C transport system permease protein YejE

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


:

Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 653.97  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160   1 MKGLNPVNQARWARFRHNRRGYWSLWIFAVIFALSLCAELIANDKPLAVHYQDRWYFPLIHSYSESDFGGPLATPADYQD 80
Cdd:PRK15021    1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160  81 PWLQQRLEEKGWVLWAPVRFSGTAINFASDHPFPAPPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGIT 160
Cdd:PRK15021   81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 161 VGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQA 240
Cdd:PRK15021  161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 241 LGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLGLTAFFSVAIL 320
Cdd:PRK15021  241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                         330       340
                  ....*....|....*....|.
gi 1126562160 321 LSLLIFIGEAVRDAFDPGKAV 341
Cdd:PRK15021  321 LSLLIFIGEAVRDAFDPNKAV 341
 
Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 653.97  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160   1 MKGLNPVNQARWARFRHNRRGYWSLWIFAVIFALSLCAELIANDKPLAVHYQDRWYFPLIHSYSESDFGGPLATPADYQD 80
Cdd:PRK15021    1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160  81 PWLQQRLEEKGWVLWAPVRFSGTAINFASDHPFPAPPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGIT 160
Cdd:PRK15021   81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 161 VGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQA 240
Cdd:PRK15021  161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 241 LGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLGLTAFFSVAIL 320
Cdd:PRK15021  241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                         330       340
                  ....*....|....*....|.
gi 1126562160 321 LSLLIFIGEAVRDAFDPGKAV 341
Cdd:PRK15021  321 LSLLIFIGEAVRDAFDPNKAV 341
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 624.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160   1 MKGLNPVNQARWARFRHNRRGYWSLWIFAVIFALSLCAELIANDKPLAVHYQDRWYFPLIHSYSESDFGGPLATPADYQD 80
Cdd:COG4239     1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160  81 PWLQQRLEEKGWVLWAPVRFSGTAINFASDHPFPAPPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGIT 160
Cdd:COG4239    81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 161 VGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQA 240
Cdd:COG4239   161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 241 LGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLGLTAFFSVAIL 320
Cdd:COG4239   241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                         330       340
                  ....*....|....*....|
gi 1126562160 321 LSLLIFIGEAVRDAFDPGKA 340
Cdd:COG4239   321 LSLLVFIGEAVRDAFDPRKT 340
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-338 7.74e-21

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 88.12  E-value: 7.74e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 158 GITVGAIQG-YYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPG----FWWLLLITVLFGWMALVGVVRAEFLRTRNF 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 233 DYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGfglplGSPSLGELLLQGKNNLEAPWlGLT 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*.
gi 1126562160 313 AFFSVAILLSLLIFIGEAVRDAFDPG 338
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 141-324 1.99e-19

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 84.64  E-value: 1.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 141 RISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSV--------VQPGFWWLLLITVL 212
Cdd:cd06261     2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLfgvllgwgILPGLGLPALILAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 213 FGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGsps 292
Cdd:cd06261    82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG--- 158

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1126562160 293 LGELLLQGKNNLEAPWLGLTAFFSVAILLSLL 324
Cdd:cd06261   159 PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 653.97  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160   1 MKGLNPVNQARWARFRHNRRGYWSLWIFAVIFALSLCAELIANDKPLAVHYQDRWYFPLIHSYSESDFGGPLATPADYQD 80
Cdd:PRK15021    1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160  81 PWLQQRLEEKGWVLWAPVRFSGTAINFASDHPFPAPPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGIT 160
Cdd:PRK15021   81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 161 VGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQA 240
Cdd:PRK15021  161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 241 LGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLGLTAFFSVAIL 320
Cdd:PRK15021  241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                         330       340
                  ....*....|....*....|.
gi 1126562160 321 LSLLIFIGEAVRDAFDPGKAV 341
Cdd:PRK15021  321 LSLLIFIGEAVRDAFDPNKAV 341
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 624.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160   1 MKGLNPVNQARWARFRHNRRGYWSLWIFAVIFALSLCAELIANDKPLAVHYQDRWYFPLIHSYSESDFGGPLATPADYQD 80
Cdd:COG4239     1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160  81 PWLQQRLEEKGWVLWAPVRFSGTAINFASDHPFPAPPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGIT 160
Cdd:COG4239    81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 161 VGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQA 240
Cdd:COG4239   161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 241 LGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLGLTAFFSVAIL 320
Cdd:COG4239   241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                         330       340
                  ....*....|....*....|
gi 1126562160 321 LSLLIFIGEAVRDAFDPGKA 340
Cdd:COG4239   321 LSLLVFIGEAVRDAFDPRKT 340
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 9-336 4.52e-65

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 206.89  E-value: 4.52e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160   9 QARWARFRHNRRGYWSLWIFAVIFALSLCAELIANDKPLAVHYQDRWyfplihsysesdfggplatpadyqdpwlqqrle 88
Cdd:COG1173     6 RRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARL--------------------------------- 52

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160  89 ekgwvlwapvrfsgtainfasdhpfpAPPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYY 168
Cdd:COG1173    53 --------------------------QPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYF 106

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 169 GGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAI 248
Cdd:COG1173   107 GGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRI 186

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 249 IWRHMLPNAM-----VATLTFlpfilcsSITVLTE--LDFLGFGLPLGSPSLGELLLQGKNNLE-APWLGLTAFFSVAIL 320
Cdd:COG1173   187 IFRHILPNVLpplivQATLGI-------ASAILAEagLSFLGLGVQPPTPSWGTMLSEGRNYLLtAPWLALFPGLAIVLT 259

                         330
                  ....*....|....*.
gi 1126562160 321 LSLLIFIGEAVRDAFD 336
Cdd:COG1173   260 VLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 115-337 5.23e-33

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 124.18  E-value: 5.23e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 115 APP--SAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLI 192
Cdd:PRK15406   74 SAPdmESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFV 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 193 IILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSS 272
Cdd:PRK15406  154 ILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSM 233

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1126562160 273 ITVLTELDFLGFGLPLGSPSLGELLLQGKNNLE-APWLGLTAFFSVAILLSLLIFIGEAVRDAFDP 337
Cdd:PRK15406  234 ILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDP 299
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 115-337 7.27e-29

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 112.90  E-value: 7.27e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 115 APPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIII 194
Cdd:PRK15082   74 AGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIA 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 195 LSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSIT 274
Cdd:PRK15082  154 VVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSII 233

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1126562160 275 VLTELDFLGFGLPLGSPSLGELLLQGKNNL-EAPWLGLtaFFSVAILLSLLIF--IGEAVRDAFDP 337
Cdd:PRK15082  234 TAASLSFLGLGAQPPTPEWGAMLNEARADMvIAPHVAL--FPSLAIFLTVLAFnlLGDGLRDALDP 297
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
115-337 3.97e-28

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 111.06  E-value: 3.97e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 115 APPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIII 194
Cdd:PRK09881   68 LPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMA 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 195 LSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSIT 274
Cdd:PRK09881  148 LAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAIL 227

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1126562160 275 VLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLgLTAFFSVAILLSLLIF--IGEAVRDAFDP 337
Cdd:PRK09881  228 MAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWW-YCAFPGAAILLTAVGFnlFGDGIRDLLDP 291
nikC PRK10417
nickel transporter permease NikC; Provisional
 116-337 6.97e-25

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 101.67  E-value: 6.97e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 116 PPSAQNWLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIIL 195
Cdd:PRK10417   42 SPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFM 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 196 SSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITV 275
Cdd:PRK10417  122 VGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLH 201

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1126562160 276 LTELDFLGFGLPLGSPSLGELLLQGKNNL-EAP----WLGLTAFFSVAILLSLlifiGEAVRDAFDP 337
Cdd:PRK10417  202 VAGLSFLGLGVTAPTAEWGVMINDARQYIwTQPllmfWPGLALFISVMAFNLL----GDALRDHLDP 264
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
115-337 8.72e-23

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 96.39  E-value: 8.72e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 115 APPSAQ---NW---LGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPT 188
Cdd:PRK10913   67 APPVWQeggSWahiLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPS 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 189 LFLIIILSSVVQPGFWWLLLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFI 268
Cdd:PRK10913  147 LLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLG 226

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1126562160 269 LCSSITVLTELDFLGFGLPLGSPSLGELLLQGKNNLEAPWLGLTaFFSVAILLSLLIF--IGEAVRDAFDP 337
Cdd:PRK10913  227 FSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVT-FPGLAILLTVLAFnlMGDGLRDALDP 296
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-338 7.74e-21

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 88.12  E-value: 7.74e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 158 GITVGAIQG-YYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQPG----FWWLLLITVLFGWMALVGVVRAEFLRTRNF 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 233 DYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGfglplGSPSLGELLLQGKNNLEAPWlGLT 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*.
gi 1126562160 313 AFFSVAILLSLLIFIGEAVRDAFDPG 338
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 141-324 1.99e-19

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 84.64  E-value: 1.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 141 RISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSV--------VQPGFWWLLLITVL 212
Cdd:cd06261     2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLfgvllgwgILPGLGLPALILAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 213 FGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLTELDFLGFGLPLGsps 292
Cdd:cd06261    82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG--- 158

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1126562160 293 LGELLLQGKNNLEAPWLGLTAFFSVAILLSLL 324
Cdd:cd06261   159 PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 142-325 1.65e-12

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 67.01  E-value: 1.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 142 ISLLFGLMLTFCASVLGITVGAIQGYY-GGKIDLFGQRFIEIWSGMPTLFLIIIL-------------------SSVVQP 201
Cdd:COG0601    97 VTLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPSFWLGLLLillfavklgwlpvsgrvspWEDFLD 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 202 GFWWLLL--ITVLFGWMALVG-VVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSI--TVL 276
Cdd:COG0601   177 ALRHLILpaLTLALGSLAGIArLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLggAVV 256

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1126562160 277 TELDFlgfglplGSPSLGELLLQGKNNLEAPWL-GLTAFFSVAILLSLLI 325
Cdd:COG0601   257 VETVF-------SWPGLGRLLVDAILNRDYPVVqGIVLLIAVLVVLVNLL 299
PRK15111 PRK15111
peptide ABC transporter permease SapC;
122-338 9.50e-11

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 61.64  E-value: 9.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 122 WLGTDANGGDVLARVLYGTRISLLFGLMLTFCASVLGITVGAIQGYYGGKIDLFGQRFIEIWSGMPTLFLIIILSSVVQP 201
Cdd:PRK15111   77 FLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGP 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 202 GfwwlLLITVLFGWMALVG-VVRAEFLRTR---NFDYIRAAQALGVSDRAIIWRHMLPNAMVATLTFLPFILCSSITVLT 277
Cdd:PRK15111  157 S----LSHAMFAVWLALLPrMVRSIYSAVHdelEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIA 232

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1126562160 278 ELDFLGFGLPLGSPSLGELLlqgKNNLE----APWLGLTAffSVAILLSLLI--FIGEAVRDAFDPG 338
Cdd:PRK15111  233 ALGFLDLGAQLPSPEWGAML---GDSLEliyvAPWTVMLP--GAAIMLSVLLvnLLGDGIRRAIIAG 294
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 207-283 7.84e-03

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 37.80  E-value: 7.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1126562160 207 LLITVLFGWMALVGVVRAEFLRTRNFDYIRAAQALGVSDRAIIWRHMLPNAMVATL-----TFLPFILCSS--ITVLTEL 279
Cdd:PRK15133  232 VLATVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIagfpaTFISMFFTGSllIEVMFSL 311


                  ....
gi 1126562160 280 DFLG 283
Cdd:PRK15133  312 NGLG 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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