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Conserved domains on  [gi|1148581377|ref|WP_077327963|]
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phosphopyruvate hydratase [Virgibacillus siamensis]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-426 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 889.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:COG0148     1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNV 160
Cdd:COG0148    81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 161 DIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLA 240
Cdd:COG0148   161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 241 MDVASSEIYEDGKYNLKGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTS 320
Cdd:COG0148   241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 321 KLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAK 400
Cdd:COG0148   321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400

                         410       420
                  ....*....|....*....|....*.
gi 1148581377 401 YNQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:COG0148   401 YNQLLRIEEELGDAARYAGRSAFKRL 426
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-426 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 889.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:COG0148     1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNV 160
Cdd:COG0148    81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 161 DIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLA 240
Cdd:COG0148   161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 241 MDVASSEIYEDGKYNLKGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTS 320
Cdd:COG0148   241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 321 KLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAK 400
Cdd:COG0148   321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400

                         410       420
                  ....*....|....*....|....*.
gi 1148581377 401 YNQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:COG0148   401 YNQLLRIEEELGDAARYAGRSAFKRL 426
eno PRK00077
enolase; Provisional
 1-427 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 858.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:PRK00077    1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNV 160
Cdd:PRK00077   81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 161 DIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLA 240
Cdd:PRK00077  161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 241 MDVASSEIYEDGKYNLKGEGvvRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTS 320
Cdd:PRK00077  241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 321 KLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAK 400
Cdd:PRK00077  319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398

                         410       420
                  ....*....|....*....|....*..
gi 1148581377 401 YNQLLRIEDELAGMGEYGGLKSFYNLK 427
Cdd:PRK00077  399 YNQLLRIEEELGDAARYAGKKAFKNLK 425
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-426 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 753.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   4 ITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELLGVD 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  84 VTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNVDIQ 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 164 EFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLAMDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 244 ASSEIY--EDGKYNLKGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTSK 321
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 322 LSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAKY 401
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400

                         410       420
                  ....*....|....*....|....*
gi 1148581377 402 NQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-410 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 735.06  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   6 DVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELLGVDVT 85
Cdd:cd03313     1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  86 RQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNVDIQEF 165
Cdd:cd03313    81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 166 MIMPVAAPTFKEALRTGAEIFHALKNVLKSKG--YNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLAMDV 243
Cdd:cd03313   161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 244 ASSEIYEDGKYNLKG-EGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTSKL 322
Cdd:cd03313   241 AASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 323 SQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAKYN 402
Cdd:cd03313   321 KKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYN 400


                  ....*...
gi 1148581377 403 QLLRIEDE 410
Cdd:cd03313   401 QLLRIEEE 408
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
139-426 1.13e-164

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 464.64  E-value: 1.13e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 139 AKTLPTPMMNILNGGEHADNNVDIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGY--NTGVGDEGGFAPNLKSNE 216
Cdd:pfam00113   1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGqsATNVGDEGGFAPNLQSNK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 217 EALETIVEAIEAAGYKPgeEVKLAMDVASSEIY--EDGKYNLKGEG------VVRTSAEMVDWYEVLINKYPIISIEDGL 288
Cdd:pfam00113  81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 289 DENDWEGHKLLTDRIGDRVQLVGDDLFVTNTSKLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSG 368
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1148581377 369 ETEDATIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-426 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 889.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:COG0148     1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNV 160
Cdd:COG0148    81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 161 DIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLA 240
Cdd:COG0148   161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 241 MDVASSEIYEDGKYNLKGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTS 320
Cdd:COG0148   241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 321 KLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAK 400
Cdd:COG0148   321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400

                         410       420
                  ....*....|....*....|....*.
gi 1148581377 401 YNQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:COG0148   401 YNQLLRIEEELGDAARYAGRSAFKRL 426
eno PRK00077
enolase; Provisional
 1-427 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 858.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:PRK00077    1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNV 160
Cdd:PRK00077   81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 161 DIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLA 240
Cdd:PRK00077  161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 241 MDVASSEIYEDGKYNLKGEGvvRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTS 320
Cdd:PRK00077  241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 321 KLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAK 400
Cdd:PRK00077  319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398

                         410       420
                  ....*....|....*....|....*..
gi 1148581377 401 YNQLLRIEDELAGMGEYGGLKSFYNLK 427
Cdd:PRK00077  399 YNQLLRIEEELGDAARYAGKKAFKNLK 425
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-426 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 753.04  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   4 ITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELLGVD 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  84 VTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNVDIQ 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 164 EFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLAMDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 244 ASSEIY--EDGKYNLKGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTSK 321
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 322 LSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAKY 401
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400

                         410       420
                  ....*....|....*....|....*
gi 1148581377 402 NQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-410 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 735.06  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   6 DVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELLGVDVT 85
Cdd:cd03313     1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  86 RQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNGGEHADNNVDIQEF 165
Cdd:cd03313    81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 166 MIMPVAAPTFKEALRTGAEIFHALKNVLKSKG--YNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKPGEEVKLAMDV 243
Cdd:cd03313   161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 244 ASSEIYEDGKYNLKG-EGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTNTSKL 322
Cdd:cd03313   241 AASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 323 SQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTDRVAKYN 402
Cdd:cd03313   321 KKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYN 400


                  ....*...
gi 1148581377 403 QLLRIEDE 410
Cdd:cd03313   401 QLLRIEEE 408
PTZ00081 PTZ00081
enolase; Provisional
 1-419 0e+00

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 564.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAAlVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:PTZ00081    1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVFRAA-VPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIE-LDGTEN-----KRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKT-----LPTPMMNI 149
Cdd:PTZ00081   80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPtdkfvLPVPCFNV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 150 LNGGEHADNNVDIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKgYN---TGVGDEGGFAPNLKSNEEALETIVEAI 226
Cdd:PTZ00081  160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKK-YGldaTNVGDEGGFAPNIKDPEEALDLLVEAI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 227 EAAGYKpgEEVKLAMDVASSEIY--EDGKYNL------KGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKL 298
Cdd:PTZ00081  239 KKAGYE--GKVKICMDVAASEFYdkEKKVYDLdfknpnNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAK 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 299 LTDRIGDRVQLVGDDLFVTNTSKLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADI 378
Cdd:PTZ00081  317 LTAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADL 396

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 1148581377 379 AVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELAGMGEYGG 419
Cdd:PTZ00081  397 VVGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
PLN00191 PLN00191
enolase
 1-419 0e+00

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 535.06  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGAFGAAlVPSGASTGEYEAVELRDGDKnRYLGKGVEKAVQNVNDVIAPELL 80
Cdd:PLN00191   25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMFRAA-VPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNY---LGGFNAKTLPTPMMNILNGGEHAD 157
Cdd:PLN00191  103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 158 NNVDIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSK--GYNTGVGDEGGFAPNLKSNEEALETIVEAIEAAGYKpgE 235
Cdd:PLN00191  183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT--G 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 236 EVKLAMDVASSEIY-EDGKYNL------KGEGVVRTSAEMVDWYEVLINKYPIISIEDGLDENDWEGHKLLTDRigDRVQ 308
Cdd:PLN00191  261 KIKIGMDVAASEFYtKDKKYDLdfkeenNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDVQ 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 309 LVGDDLFVTNTSKLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIK 388
Cdd:PLN00191  339 IVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIK 418

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1148581377 389 TGAPSRTDRVAKYNQLLRIEDELAGMGEYGG 419
Cdd:PLN00191  419 TGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
139-426 1.13e-164

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 464.64  E-value: 1.13e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 139 AKTLPTPMMNILNGGEHADNNVDIQEFMIMPVAAPTFKEALRTGAEIFHALKNVLKSKGY--NTGVGDEGGFAPNLKSNE 216
Cdd:pfam00113   1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGqsATNVGDEGGFAPNLQSNK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 217 EALETIVEAIEAAGYKPgeEVKLAMDVASSEIY--EDGKYNLKGEG------VVRTSAEMVDWYEVLINKYPIISIEDGL 288
Cdd:pfam00113  81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 289 DENDWEGHKLLTDRIGDRVQLVGDDLFVTNTSKLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSG 368
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1148581377 369 ETEDATIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELAGMGEYGGLKSFYNL 426
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
Enolase_N pfam03952
Enolase, N-terminal domain;
4-134 3.32e-76

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 233.04  E-value: 3.32e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   4 ITDVYAREVLDSRGNPTVEVEVSTESGAFGAALVPSGASTGEYEAVELRDGDKNRYLGKGVEKAVQNVNDVIAPELLGVD 83
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1148581377  84 VTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYL 134
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
PRK08350 PRK08350
hypothetical protein; Provisional
 1-423 6.78e-18

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 84.47  E-value: 6.78e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377   1 MPYITDVYAREVLDSRGNPTVEVEVSTESGaFGAALVPSgastgeyeavelrDGDKNRYLGKGvEKAVQNVNDVIAPELL 80
Cdd:PRK08350    1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  81 GVDVTRQNIIDQIMIELDGTENKRNLGANAILGVSMAAAHAASSYLGLPLYNYLGGFNAKTLPTPMMNILNgGEHADNNV 160
Cdd:PRK08350   66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAE-DENFEYYV 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 161 DIQEFMimpvaaptfkealrtgaEIFHALKNVLKSKGYntgvgdeggfapnlkSNEEALETIVEAIEAAGYKPGEEVKLA 240
Cdd:PRK08350  145 LVRDLM-----------------EITDVVDAVNKILEN---------------SKEVSLEGLSKASEKAGDELGLEVALG 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 241 MDVasseiyedgKYNLKGEGVVRTsaemVDWYEVLINKyPIISIEDGLdENDWEGHKLLTDrigdrvqlvGDDLFVTNTS 320
Cdd:PRK08350  193 IAQ---------KREMETEKVLNL----VEDNNIAYIK-PIGDEELFL-ELIAGTHGVFID---------GEYLFRTRNI 248

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 321 klsqgIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSGETEDATIADIAVATNAGQIKTgapsRTDRVAK 400
Cdd:PRK08350  249 -----LDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAMLI----HKDSVEK 319

                         410       420
                  ....*....|....*....|...
gi 1148581377 401 YNQLLRIEDELagmGEYGGLKSF 423
Cdd:PRK08350  320 INELNRIAEDL---GERGRIITF 339
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 214-389 5.44e-14

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 70.82  E-value: 5.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 214 SNEEALETIVEAIeaagykpGEEVKLAMDVASSeiyedgkYNLKgegvvrtsaEMVDWYEVLiNKYPIISIEDGLDENDW 293
Cdd:cd00308    79 GSIERVRAVREAF-------GPDARLAVDANGA-------WTPK---------EAIRLIRAL-EKYGLAWIEEPCAPDDL 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 294 EGHKLLTDRIGdrVQLVGDDLFVTNTSKLsQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAGYTAVISHRSG-ETED 372
Cdd:cd00308   135 EGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsSIGT 211

                         170
                  ....*....|....*...
gi 1148581377 373 ATIADIAVAT-NAGQIKT 389
Cdd:cd00308   212 AAALHLAAALpNDRAIET 229
PTZ00378 PTZ00378
hypothetical protein; Provisional
 184-414 2.24e-04

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 43.33  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 184 EIFHALKNVLKSkgYNTGVGDEGGFAPNLKSN-EEALETIVEAIEAAGYKPGEEVKLAMDVASSEIYEDGKYNLKGegvv 262
Cdd:PTZ00378  230 KIFAAFHHFCQS--HNSSVRSDGSLHWDGFANlTDAVKLATEALRAVQLTPGTDVCLGLRMAASTTRVPATAVADG---- 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 263 RTSAEMVDWYEVLINKYP------------------------IISIEDGLDENDWEGHKLLTDRIGDRVQLVGDDLFVTN 318
Cdd:PTZ00378  304 GAWKEAKDDCEVLYSLFPgepdvtgdqlseyvreqlqavpdiVVYVEDTHCDEDTFGLQRLQAALGDSIVLSGVDVYARS 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 319 TS-KLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKR-AGYTAVISHRSGETEDATIADIAVATNAGQIKTGAPSRTD 396
Cdd:PTZ00378  384 EYkKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEdEGRAVTVLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAH 463

                         250
                  ....*....|....*...
gi 1148581377 397 RVAKYNQLLRIEDELAGM 414
Cdd:PTZ00378  464 QCEVVSQLASRQDELTHS 481
RspA COG4948
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ...
 63-358 8.05e-03

L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 443975 [Multi-domain]  Cd Length: 359  Bit Score: 38.26  E-value: 8.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377  63 GVEKAVQNVNDVIAPELLGVDVTRqniIDQIMIELDGTENKRNLGANA-------ILGvsmaaahaasSYLGLPLYNYLG 135
Cdd:COG4948    54 GAEAVAAALEEALAPLLIGRDPLD---IEALWQRLYRALPGNPAAKAAvdmalwdLLG----------KALGVPVYQLLG 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 136 GFNAKTLPTpmmnilnggehaDNNVDIQEFMIMPVAAptfKEALRTGaeiFHALKnvLKskgyntgvgdegGFAPNLKSN 215
Cdd:COG4948   121 GKVRDRVPV------------YATLGIDTPEEMAEEA---REAVARG---FRALK--LK------------VGGPDPEED 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1148581377 216 EEALETIVEAIeaagykpGEEVKLAMDVasseiyeDGKYNLKgegvvrTSAEMVDWYEvlinKYPIISIEDGLDENDWEG 295
Cdd:COG4948   169 VERVRAVREAV-------GPDARLRVDA-------NGAWTLE------EAIRLLRALE----DLGLEWIEQPLPAEDLEG 224

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1148581377 296 HKLLTDRIgdRVQLVGDDLfVTNTSKLSQGIEQGVGNSILVKVNQIGTLTETFEAVEMAKRAG 358
Cdd:COG4948   225 LAELRRAT--PVPIAADES-LTSRADFRRLIEAGAVDIVNIKLSKVGGLTEALRIAALAEAHG 284
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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