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Conserved domains on  [gi|1154979290|ref|WP_078884611|]
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MULTISPECIES: O-methyltransferase [Streptomyces]

Protein Classification

O-methyltransferase( domain architecture ID 11467877)

O-methyltransferase of the class I-like SAM-binding methyltransferase superfamily, such as catechol O-methyltransferases that can use various catechol-like compounds

CATH:  2.20.25.110
EC:  2.1.1.-|2.1.-.-
Gene Ontology:  GO:0008757|GO:0032259|GO:1904047|GO:0008168|GO:0008171
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 81-232 5.29e-61

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


:

Pssm-ID: 443298  Cd Length: 173  Bit Score: 188.85  E-value: 5.29e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRALDVLPRLADAGYDLVFCDGDRLE 160
Cdd:COG4122    22 EIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARAGLA-DRIRLILGDALEVLPRLADGPFDLVFIDADKSN 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1154979290 161 YLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQELVPSLLPVGDGLLCAVKR 232
Cdd:COG4122   101 YPDYLELALPLLRPGGLIVADNVLWHGRVADPARRDPSTRAIREFNEYLREDPRLESVLLPIGDGLLLARKR 172
 
Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 81-232 5.29e-61

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 188.85  E-value: 5.29e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRALDVLPRLADAGYDLVFCDGDRLE 160
Cdd:COG4122    22 EIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARAGLA-DRIRLILGDALEVLPRLADGPFDLVFIDADKSN 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1154979290 161 YLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQELVPSLLPVGDGLLCAVKR 232
Cdd:COG4122   101 YPDYLELALPLLRPGGLIVADNVLWHGRVADPARRDPSTRAIREFNEYLREDPRLESVLLPIGDGLLLARKR 172
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 59-231 1.70e-21

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 88.32  E-value: 1.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  59 VTPGTGSALGLLAAAVDAKAVAEIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRAL 138
Cdd:pfam01596  27 VSPDEGQFLGMLVKLTGAKNVLEIGVFTGYSALAMALALPEDGKITAIDIDPEAYEIAKKFIQKAGVA-HKISFILGPAL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 139 DVLPRLADAG----YDLVFCDGDRLEYLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQE 214
Cdd:pfam01596 106 KVLEQLTQDKplpeFDFIFIDADKSNYPNYYERLLELLKVGGLMAIDNTLWHGKVTEPDDQEAKTQRLQEFNKDLAQDPR 185

                         170
                  ....*....|....*..
gi 1154979290 215 LVPSLLPVGDGLLCAVK 231
Cdd:pfam01596 186 VEISVIPVGDGITLCRK 202
PLN02476 PLN02476
O-methyltransferase
 59-232 1.37e-11

O-methyltransferase


Pssm-ID: 178094  Cd Length: 278  Bit Score: 62.39  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  59 VTPGTGSALGLLAAAVDAKAVAEIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGfASNRARFIPGRAL 138
Cdd:PLN02476  102 VSPDQAQLLAMLVQILGAERCIEVGVYTGYSSLAVALVLPESGCLVACERDSNSLEVAKRYYELAG-VSHKVNVKHGLAA 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 139 DVLPRL----ADAGYDLVFCDGDRLEYLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQE 214
Cdd:PLN02476  181 ESLKSMiqngEGSSYDFAFVDADKRMYQDYFELLLQLVRVGGVIVMDNVLWHGRVADPLVNDAKTISIRNFNKKLMDDKR 260

                         170
                  ....*....|....*...
gi 1154979290 215 LVPSLLPVGDGLLCAVKR 232
Cdd:PLN02476  261 VSISMVPIGDGMTICRKR 278
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 81-185 1.04e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 48.58  E-value: 1.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHgmRPDGVLTTVDPEPEHQQFARQAFRAAGFasNRARFIPGRALDVLPrLADAGYDLVFCDG---- 156
Cdd:cd02440     4 DLGCGTGALALALAS--GPGARVTGVDISPVALELARKAAAALLA--DNVEVLKGDAEELPP-EADESFDVIISDPplhh 78

                          90       100
                  ....*....|....*....|....*....
gi 1154979290 157 DRLEYLDYLAESLRLLRPGGLVAFEGVFG 185
Cdd:cd02440    79 LVEDLARFLEEARRLLKPGGVLVLTLVLA 107
 
Name Accession Description Interval E-value
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 81-232 5.29e-61

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 188.85  E-value: 5.29e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRALDVLPRLADAGYDLVFCDGDRLE 160
Cdd:COG4122    22 EIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARAGLA-DRIRLILGDALEVLPRLADGPFDLVFIDADKSN 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1154979290 161 YLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQELVPSLLPVGDGLLCAVKR 232
Cdd:COG4122   101 YPDYLELALPLLRPGGLIVADNVLWHGRVADPARRDPSTRAIREFNEYLREDPRLESVLLPIGDGLLLARKR 172
Methyltransf_3 pfam01596
O-methyltransferase; Members of this family are O-methyltransferases. The family includes ...
 59-231 1.70e-21

O-methyltransferase; Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.


Pssm-ID: 396257 [Multi-domain]  Cd Length: 203  Bit Score: 88.32  E-value: 1.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  59 VTPGTGSALGLLAAAVDAKAVAEIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRAL 138
Cdd:pfam01596  27 VSPDEGQFLGMLVKLTGAKNVLEIGVFTGYSALAMALALPEDGKITAIDIDPEAYEIAKKFIQKAGVA-HKISFILGPAL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 139 DVLPRLADAG----YDLVFCDGDRLEYLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQE 214
Cdd:pfam01596 106 KVLEQLTQDKplpeFDFIFIDADKSNYPNYYERLLELLKVGGLMAIDNTLWHGKVTEPDDQEAKTQRLQEFNKDLAQDPR 185

                         170
                  ....*....|....*..
gi 1154979290 215 LVPSLLPVGDGLLCAVK 231
Cdd:pfam01596 186 VEISVIPVGDGITLCRK 202
Methyltransf_24 pfam13578
Methyltransferase domain; This family appears to be a methyltransferase domain.
 81-180 1.01e-17

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 433324 [Multi-domain]  Cd Length: 106  Bit Score: 75.42  E-value: 1.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDG--VLTTVDPEPEHQQFARQAfrAAGFASNRARFIPGRALDVLPRLADAGYDLVFCDGD- 157
Cdd:pfam13578   2 EIGTYSGVSTLWLAAALRDNGlgRLTAVDPDPGAEEAGALL--RKAGLDDRVRLIVGDSREALPSLADGPIDLLFIDGDh 79

                          90       100
                  ....*....|....*....|....*
gi 1154979290 158 --RLEYLDYLAeSLRLLRPGGLVAF 180
Cdd:pfam13578  80 tyEAVLNDLEL-WLPRLAPGGVILF 103
PLN02476 PLN02476
O-methyltransferase
 59-232 1.37e-11

O-methyltransferase


Pssm-ID: 178094  Cd Length: 278  Bit Score: 62.39  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  59 VTPGTGSALGLLAAAVDAKAVAEIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGfASNRARFIPGRAL 138
Cdd:PLN02476  102 VSPDQAQLLAMLVQILGAERCIEVGVYTGYSSLAVALVLPESGCLVACERDSNSLEVAKRYYELAG-VSHKVNVKHGLAA 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 139 DVLPRL----ADAGYDLVFCDGDRLEYLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLRVRELLRAVRESQE 214
Cdd:PLN02476  181 ESLKSMiqngEGSSYDFAFVDADKRMYQDYFELLLQLVRVGGVIVMDNVLWHGRVADPLVNDAKTISIRNFNKKLMDDKR 260

                         170
                  ....*....|....*...
gi 1154979290 215 LVPSLLPVGDGLLCAVKR 232
Cdd:PLN02476  261 VSISMVPIGDGMTICRKR 278
PLN02589 PLN02589
caffeoyl-CoA O-methyltransferase
 64-228 1.07e-09

caffeoyl-CoA O-methyltransferase


Pssm-ID: 166230  Cd Length: 247  Bit Score: 56.93  E-value: 1.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  64 GSALGLLAAAVDAKAVAEIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRALDVLPR 143
Cdd:PLN02589   68 GQFLNMLLKLINAKNTMEIGVYTGYSLLATALALPEDGKILAMDINRENYELGLPVIQKAGVA-HKIDFREGPALPVLDQ 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 144 LADAG-----YDLVFCDGDRLEYLDYLAESLRLLRPGGLVAFEGVFGAGRTIdsGPqPTEVLR---------VRELLRAV 209
Cdd:PLN02589  147 MIEDGkyhgtFDFIFVDADKDNYINYHKRLIDLVKVGGVIGYDNTLWNGSVV--AP-PDAPMRkyvryyrdfVLELNKAL 223

                         170       180
                  ....*....|....*....|
gi 1154979290 210 RESQELVPSLLPVGDGL-LC 228
Cdd:PLN02589  224 AADPRIEICMLPVGDGItLC 243
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 81-180 3.52e-08

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 51.08  E-value: 3.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLL--HGMRpdgvLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRALDVLPrlaDAGYDLVFCDG-- 156
Cdd:COG2230    57 DIGCGWGGLALYLArrYGVR----VTGVTLSPEQLEYARERAAEAGLA-DRVEVRLADYRDLPA---DGQFDAIVSIGmf 128

                          90       100
                  ....*....|....*....|....*..
gi 1154979290 157 ---DRLEYLDYLAESLRLLRPGGLVAF 180
Cdd:COG2230   129 ehvGPENYPAYFAKVARLLKPGGRLLL 155
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 81-176 4.47e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 49.48  E-value: 4.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHgmRPDGVLTTVDPEPEHQQFARQAFRAAGFasnRARFIPGRALDvLPrLADAGYDLVFCDG---- 156
Cdd:pfam13649   3 DLGCGTGRLTLALAR--RGGARVTGVDLSPEMLERARERAAEAGL---NVEFVQGDAED-LP-FPDGSFDLVVSSGvlhh 75

                          90       100
                  ....*....|....*....|.
gi 1154979290 157 -DRLEYLDYLAESLRLLRPGG 176
Cdd:pfam13649  76 lPDPDLEAALREIARVLKPGG 96
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 81-180 6.22e-08

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 51.70  E-value: 6.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFaSNRARFIPGRALDVLPrlaDAGYDLVFCD-GDRL 159
Cdd:COG2519    97 EAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGL-PDNVELKLGDIREGID---EGDVDAVFLDmPDPW 172

                          90       100
                  ....*....|....*....|.
gi 1154979290 160 EYLDYLAESlrlLRPGGLVAF 180
Cdd:COG2519   173 EALEAVAKA---LKPGGVLVA 190
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 81-185 1.04e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 48.58  E-value: 1.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHgmRPDGVLTTVDPEPEHQQFARQAFRAAGFasNRARFIPGRALDVLPrLADAGYDLVFCDG---- 156
Cdd:cd02440     4 DLGCGTGALALALAS--GPGARVTGVDISPVALELARKAAAALLA--DNVEVLKGDAEELPP-EADESFDVIISDPplhh 78

                          90       100
                  ....*....|....*....|....*....
gi 1154979290 157 DRLEYLDYLAESLRLLRPGGLVAFEGVFG 185
Cdd:cd02440    79 LVEDLARFLEEARRLLKPGGVLVLTLVLA 107
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 81-184 2.32e-07

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 49.53  E-value: 2.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHgmRPDGVLTTVDPEPEHQQFARQAFRAAGFAsnRARFIPGRALDVLPrLADAGYDLVFCDG---- 156
Cdd:COG0500    32 DLGCGTGRNLLALAA--RFGGRVIGIDLSPEAIALARARAAKAGLG--NVEFLVADLAELDP-LPAESFDLVVAFGvlhh 106

                          90       100
                  ....*....|....*....|....*....
gi 1154979290 157 -DRLEYLDYLAESLRLLRPGGLVAFEGVF 184
Cdd:COG0500   107 lPPEEREALLRELARALKPGGVLLLSASD 135
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 85-180 1.10e-06

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 46.53  E-value: 1.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  85 GCGvSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFasnRARFIPGRALDvLPrLADAGYDLVFCdGDRLEYLDY 164
Cdd:COG2226    30 GCG-TGRLALALAERGARVTGVDISPEMLELARERAAEAGL---NVEFVVGDAED-LP-FPDGSFDLVIS-SFVLHHLPD 102

                          90       100
                  ....*....|....*....|
gi 1154979290 165 ----LAESLRLLRPGGLVAF 180
Cdd:COG2226   103 peraLAEIARVLKPGGRLVV 122
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 81-181 1.95e-06

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 46.26  E-value: 1.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsnRARFIPGRALDVLPRLADAGYDLVFCDG--DR 158
Cdd:pfam13847   9 DLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQKLGFD--NVEFEQGDIEELPELLEDDKFDVVISNCvlNH 86

                          90       100
                  ....*....|....*....|....
gi 1154979290 159 LEYLD-YLAESLRLLRPGGLVAFE 181
Cdd:pfam13847  87 IPDPDkVLQEILRVLKPGGRLIIS 110
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 85-181 3.89e-06

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 44.62  E-value: 3.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  85 GCGvSGIHLLHgMRPDGVLTT-VDPEPEHQQFARQAFRAAgfasnRARFIPGRALDVlpRLADAGYDLVFCdGDRLEYL- 162
Cdd:COG2227    32 GCG-TGRLALA-LARRGADVTgVDISPEALEIARERAAEL-----NVDFVQGDLEDL--PLEDGSFDLVIC-SEVLEHLp 101

                          90       100
                  ....*....|....*....|..
gi 1154979290 163 ---DYLAESLRLLRPGGLVAFE 181
Cdd:COG2227   102 dpaALLRELARLLKPGGLLLLS 123
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 85-180 6.20e-06

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 43.42  E-value: 6.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  85 GCGvSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsnrarFIPGRALDvLPrLADAGYDLVFCdGDRLEYLDY 164
Cdd:pfam08241   4 GCG-TGLLTELLARLGARVTGVDISPEMLELAREKAPREGLT-----FVVGDAED-LP-FPDNSFDLVLS-SEVLHHVED 74

                          90       100
                  ....*....|....*....|
gi 1154979290 165 ----LAESLRLLRPGGLVAF 180
Cdd:pfam08241  75 peraLREIARVLKPGGILII 94
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 81-180 6.28e-06

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 45.91  E-value: 6.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIhLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGFAsNRARFIPGRALDVLPRLADAGYDLVFC------ 154
Cdd:COG4123    43 DLGTGTGVIAL-MLAQRSPGARITGVEIQPEAAELARRNVALNGLE-DRITVIHGDLKEFAAELPPGSFDLVVSnppyfk 120

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1154979290 155 --------DGDR--------LEYLDYLAESLRLLRPGGLVAF 180
Cdd:COG4123   121 agsgrkspDEARaiarhedaLTLEDLIRAAARLLKPGGRFAL 162
PLN02781 PLN02781
Probable caffeoyl-CoA O-methyltransferase
 81-228 7.16e-06

Probable caffeoyl-CoA O-methyltransferase


Pssm-ID: 215417  Cd Length: 234  Bit Score: 45.58  E-value: 7.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHGMRPDGVLTTVDPEPEHQQFARQAFRAAGfASNRARFIPGRALDVLPRLADAG----YDLVFCDG 156
Cdd:PLN02781   74 EIGVFTGYSLLTTALALPEDGRITAIDIDKEAYEVGLEFIKKAG-VDHKINFIQSDALSALDQLLNNDpkpeFDFAFVDA 152

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1154979290 157 DRLEYLDYLAESLRLLRPGGLVAFEGVFGAGRTIDSGPQPTEVLR-VRELLRAVRESQELVP----SLLPVGDGL-LC 228
Cdd:PLN02781  153 DKPNYVHFHEQLLKLVKVGGIIAFDNTLWFGFVAQEEDEVPEHMRaYRKALLEFNKLLASDPrveiSQISIGDGVtLC 230
RlmK COG1092
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ...
 116-180 1.40e-05

23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440709 [Multi-domain]  Cd Length: 392  Bit Score: 45.17  E-value: 1.40e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1154979290 116 ARQAFRAAGFASnRARFIPGRALDVLPRLADAG--YDLVFCD--------GDRLE----YLDYLAESLRLLRPGGLVAF 180
Cdd:COG1092   255 AKENAALNGLDD-RHEFVQADAFDWLRELAREGerFDLIILDppafakskKDLFDaqrdYKDLNRLALKLLAPGGILVT 332
RsmD COG0742
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 106-181 7.02e-05

16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440505 [Multi-domain]  Cd Length: 183  Bit Score: 41.99  E-value: 7.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 106 VDPEPEHQQFARQAFRAAGfASNRARFIPGRALDVLPRLADAGYDLVFCD-----GDRLEYLDYLAESlRLLRPGGLVAF 180
Cdd:COG0742    70 VEKDRKAAAVIRKNLEKLG-LEDRARVIRGDALRFLKRLAGEPFDLVFLDppyakGLLEKALELLAEN-GLLAPGGLIVV 147


                  .
gi 1154979290 181 E 181
Cdd:COG0742   148 E 148
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 81-178 1.69e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 39.66  E-value: 1.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSGIHLLHgMRPDGVLTTVDPEPEHQQFARQAFRAAGFASN-RARFIPGRALDVLPRladaGYDLVFCdGDRL 159
Cdd:pfam08242   2 EIGCGTGTLLRALLE-ALPGLEYTGLDISPAALEAARERLAALGLLNAvRVELFQLDLGELDPG----SFDVVVA-SNVL 75

                          90       100
                  ....*....|....*....|...
gi 1154979290 160 EYLDYLAESLR----LLRPGGLV 178
Cdd:pfam08242  76 HHLADPRAVLRnirrLLKPGGVL 98
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
81-181 3.70e-04

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 38.65  E-value: 3.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290  81 EIGTGCGVSgIHLLHGMRPDGVLTTVDPEPEHQQFARQAFraagfasNRARFIPGRALDVLPrlaDAGYDLVFCdGDRLE 160
Cdd:COG4106     7 DLGCGTGRL-TALLAERFPGARVTGVDLSPEMLARARARL-------PNVRFVVADLRDLDP---PEPFDLVVS-NAALH 74

                          90       100
                  ....*....|....*....|....*
gi 1154979290 161 YLDYLAESL----RLLRPGGLVAFE 181
Cdd:COG4106    75 WLPDHAALLarlaAALAPGGVLAVQ 99
YhdJ COG0863
DNA modification methylase [Replication, recombination and repair];
131-191 3.24e-03

DNA modification methylase [Replication, recombination and repair];


Pssm-ID: 440623  Cd Length: 236  Bit Score: 37.59  E-value: 3.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1154979290 131 RFIPGRALDVLPRLADAGYDLVFCD----------------GDRLEYLDY-------LAESLRLLRPGGLVAfegVFGAG 187
Cdd:COG0863     1 RLICGDCLEVLKELPDESVDLIVTDppynlgkkyglgrreiGNELSFEEYleflrewLAECYRVLKPGGSLY---VNIGD 77


                  ....
gi 1154979290 188 RTID 191
Cdd:COG0863    78 RYIS 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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