|
Name |
Accession |
Description |
Interval |
E-value |
| IS21_help_AAA |
NF038214 |
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ... |
8-239 |
3.36e-117 |
|
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.
Pssm-ID: 439516 Cd Length: 232 Bit Score: 334.05 E-value: 3.36e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 8 LKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYN 87
Cdd:NF038214 1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 88 LATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDEL 167
Cdd:NF038214 81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKE 239
Cdd:NF038214 161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
|
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
1-239 |
2.17e-113 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 324.81 E-value: 2.17e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 1 MSSLIKDLKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKL 80
Cdd:COG1484 3 MEELKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQPGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 81 NRQEIYNLATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPD 160
Cdd:COG1484 83 DRRQILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVD 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1160634253 161 LLILDELGFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKE 239
Cdd:COG1484 163 LLILDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKE 241
|
|
| IstB_IS21 |
pfam01695 |
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ... |
8-242 |
2.35e-88 |
|
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.
Pssm-ID: 426385 [Multi-domain] Cd Length: 238 Bit Score: 261.61 E-value: 2.35e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 8 LKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYN 87
Cdd:pfam01695 3 LKQLKLPGMAEAWEELSQQAASTSLSYEEFLEHLLEEELAWRDTRRLERLLRMAKLPPHKTLEDFDFTFAPGLDQRIVAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 88 LATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDEL 167
Cdd:pfam01695 83 LASLSFIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEW 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKEQKQ 242
Cdd:pfam01695 163 GYLPLDQAEANLLFQVISKRYEHRSIILTSNLPFGEWGQVFGDAVLATAILDRLLHHCHIVPIKGESYRLKTKSE 237
|
|
| PRK09183 |
PRK09183 |
transposase/IS protein; Provisional |
9-242 |
2.20e-70 |
|
transposase/IS protein; Provisional
Pssm-ID: 181681 Cd Length: 259 Bit Score: 216.50 E-value: 2.20e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 9 KTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYNL 88
Cdd:PRK09183 14 GQLQLESLISAAPALAQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 89 ATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKY-YLAPDLLILDEL 167
Cdd:PRK09183 94 RSLSFIERNENIVLLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRgVMAPRLLIIDEI 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIF-HDRILATAILDRIVHHCHLILIKGDSFRMKEQKQ 242
Cdd:PRK09183 174 GYLPFSQEEANLFFQVIAKRYEKGSMILTSNLPFGQWDQTFaGDAALTSAMLDRLLHHSHVVQIKGESYRLKQKRK 249
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
79-227 |
5.37e-13 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 64.47 E-value: 5.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 79 KLNRQEIYNLATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYH----RKLK 154
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLvrllFELA 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1160634253 155 YYLAPDLLILDELGF--KQLSDNIVDLFYEIISKRYETG--SVIITSNKSFddwgsifhDRILATAILDRIVHHCHL 227
Cdd:cd00009 81 EKAKPGVLFIDEIDSlsRGAQNALLRVLETLNDLRIDREnvRVIGATNRPL--------LGDLDRALYDRLDIRIVI 149
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
96-224 |
6.57e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.15 E-value: 6.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 96 KKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKY---------------YLAPD 160
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlrlalalarKLKPD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 161 LLILDELG------FKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDdwgsifHDRILATAILDRIVHH 224
Cdd:smart00382 81 VLILDEITslldaeQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKD------LGPALLRRRFDRRIVL 144
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| IS21_help_AAA |
NF038214 |
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ... |
8-239 |
3.36e-117 |
|
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.
Pssm-ID: 439516 Cd Length: 232 Bit Score: 334.05 E-value: 3.36e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 8 LKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYN 87
Cdd:NF038214 1 LRQLKLPGMARALEELAEQAAREELSFEEFLALLLEAELAERENRRIERRLKRARFPAAKTLEDFDFTAAPGLDKAQIRE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 88 LATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDEL 167
Cdd:NF038214 81 LATLDFIERAENVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQARADGRLGRLLRRLARYDLLIIDEL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKE 239
Cdd:NF038214 161 GYLPFSREGANLLFELIADRYERGSTIITSNLPFSEWGEVFGDPTLAAAILDRLVHHAHILELKGESYRLKE 232
|
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
1-239 |
2.17e-113 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 324.81 E-value: 2.17e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 1 MSSLIKDLKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKL 80
Cdd:COG1484 3 MEELKELLKALKLPGMAEALDELLAQAACDELSYEEFLALLLEAEVAEREQRRIERRLKAARFPAAKTLEDFDFDAQPGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 81 NRQEIYNLATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPD 160
Cdd:COG1484 83 DRRQILELATLDFIERGENLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVD 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1160634253 161 LLILDELGFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKE 239
Cdd:COG1484 163 LLILDELGYLPLDAEGAELLFELISDRYERRSTIITSNLPFSEWGEVFGDPTLATAILDRLVHHAHIIELKGESYRLKE 241
|
|
| IstB_IS21 |
pfam01695 |
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ... |
8-242 |
2.35e-88 |
|
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.
Pssm-ID: 426385 [Multi-domain] Cd Length: 238 Bit Score: 261.61 E-value: 2.35e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 8 LKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYN 87
Cdd:pfam01695 3 LKQLKLPGMAEAWEELSQQAASTSLSYEEFLEHLLEEELAWRDTRRLERLLRMAKLPPHKTLEDFDFTFAPGLDQRIVAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 88 LATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDEL 167
Cdd:pfam01695 83 LASLSFIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEW 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKEQKQ 242
Cdd:pfam01695 163 GYLPLDQAEANLLFQVISKRYEHRSIILTSNLPFGEWGQVFGDAVLATAILDRLLHHCHIVPIKGESYRLKTKSE 237
|
|
| PRK09183 |
PRK09183 |
transposase/IS protein; Provisional |
9-242 |
2.20e-70 |
|
transposase/IS protein; Provisional
Pssm-ID: 181681 Cd Length: 259 Bit Score: 216.50 E-value: 2.20e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 9 KTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYNL 88
Cdd:PRK09183 14 GQLQLESLISAAPALAQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 89 ATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKY-YLAPDLLILDEL 167
Cdd:PRK09183 94 RSLSFIERNENIVLLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRgVMAPRLLIIDEI 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIF-HDRILATAILDRIVHHCHLILIKGDSFRMKEQKQ 242
Cdd:PRK09183 174 GYLPFSQEEANLFFQVIAKRYEKGSMILTSNLPFGQWDQTFaGDAALTSAMLDRLLHHSHVVQIKGESYRLKQKRK 249
|
|
| PRK06526 |
PRK06526 |
transposase; Provisional |
9-240 |
2.90e-70 |
|
transposase; Provisional
Pssm-ID: 180607 Cd Length: 254 Bit Score: 215.89 E-value: 2.90e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 9 KTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYNL 88
Cdd:PRK06526 10 RALKAPTLAGAVERLAERARAESWSHEEFLAACLQREVAARESHGGEGRIRAARFPARKSLEEFDFDHQRSLKRDTIAHL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 89 ATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDELG 168
Cdd:PRK06526 90 GTLDFVTGKENVVFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAELVKLGRYPLLIVDEVG 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160634253 169 FKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFRMKEQ 240
Cdd:PRK06526 170 YIPFEPEAANLFFQLVSSRYERASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVISLKGDSYRLKDR 241
|
|
| PRK08181 |
PRK08181 |
transposase; Validated |
8-236 |
1.12e-41 |
|
transposase; Validated
Pssm-ID: 136670 [Multi-domain] Cd Length: 269 Bit Score: 143.15 E-value: 1.12e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 8 LKTLKLSGVAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYN 87
Cdd:PRK08181 16 LNELRLPTIKTLWPQFAEQADKEGWPAARFLAAIAEHELAERARRRIERHLAEAHLPPGKTLDSFDFEAVPMVSKAQVMA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 88 LATGE-YIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKAD---NSYHRKLKYYlapDLLI 163
Cdd:PRK08181 96 IAAGDsWLAKGANLLLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRElqlESAIAKLDKF---DLLI 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1160634253 164 LDELGFKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDDWGSIFHDRILATAILDRIVHHCHLILIKGDSFR 236
Cdd:PRK08181 173 LDDLAYVTKDQAETSVLFELISARYERRSILITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIFEMNVESYR 245
|
|
| PRK08116 |
PRK08116 |
hypothetical protein; Validated |
96-246 |
1.41e-19 |
|
hypothetical protein; Validated
Pssm-ID: 236153 [Multi-domain] Cd Length: 268 Bit Score: 85.07 E-value: 1.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 96 KKENI--VFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEA------KADNSYHRKLKYYlapDLLILDEL 167
Cdd:PRK08116 111 KKENVglLLWGSVGTGKTYLAACIANELIEKGVPVIFVNFPQLLNRIKSTykssgkEDENEIIRSLVNA---DLLILDDL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 168 GFKQLSDNIVDLFYEIISKRYETG-SVIITSNKSFDDWGSIFHDRilataILDRIVHHCHLILIKGDSFRMKEQKQKIEK 246
Cdd:PRK08116 188 GAERDTEWAREKVYNIIDSRYRKGlPTIVTTNLSLEELKNQYGKR-----IYDRILEMCTPVENEGKSYRKEIAKEKLQR 262
|
|
| PRK06835 |
PRK06835 |
DNA replication protein DnaC; Validated |
97-245 |
7.55e-15 |
|
DNA replication protein DnaC; Validated
Pssm-ID: 235871 [Multi-domain] Cd Length: 329 Bit Score: 72.63 E-value: 7.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 97 KENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYH--RKLKYYLAPDLLILDELGFKQLSD 174
Cdd:PRK06835 183 NENLLFYGNTGTGKTFLSNCIAKELLDRGKSVIYRTADELIEILREIRFNNDKEleEVYDLLINCDLLIIDDLGTEKITE 262
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160634253 175 NIVDLFYEIISKRYETG-SVIITSNKSFDDWGSIFHDRilataILDRIVHHCHLILIKGDSFRMKEQKQKIE 245
Cdd:PRK06835 263 FSKSELFNLINKRLLRQkKMIISTNLSLEELLKTYSER-----ISSRLLGNFTLLKFYGEDIRIKKNLQKKN 329
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
79-227 |
5.37e-13 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 64.47 E-value: 5.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 79 KLNRQEIYNLATGEYIRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYH----RKLK 154
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLvrllFELA 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1160634253 155 YYLAPDLLILDELGF--KQLSDNIVDLFYEIISKRYETG--SVIITSNKSFddwgsifhDRILATAILDRIVHHCHL 227
Cdd:cd00009 81 EKAKPGVLFIDEIDSlsRGAQNALLRVLETLNDLRIDREnvRVIGATNRPL--------LGDLDRALYDRLDIRIVI 149
|
|
| PRK12377 |
PRK12377 |
putative replication protein; Provisional |
99-213 |
8.98e-11 |
|
putative replication protein; Provisional
Pssm-ID: 183482 [Multi-domain] Cd Length: 248 Bit Score: 60.23 E-value: 8.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 99 NIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKAD-NSYHRKLKYYLAPDLLILDELGFKQLSDNIV 177
Cdd:PRK12377 103 NFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVTVPDVMSRLHESYDNgQSGEKFLQELCKVDLLVLDEIGIQRETKNEQ 182
|
90 100 110
....*....|....*....|....*....|....*..
gi 1160634253 178 DLFYEIISKRYET-GSVIITSNKSFDDWGSIFHDRIL 213
Cdd:PRK12377 183 VVLNQIIDRRTASmRSVGMLTNLNHEAMSTLLGERVM 219
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
96-224 |
6.57e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.15 E-value: 6.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 96 KKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKY---------------YLAPD 160
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlrlalalarKLKPD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 161 LLILDELG------FKQLSDNIVDLFYEIISKRYETGSVIITSNKSFDdwgsifHDRILATAILDRIVHH 224
Cdd:smart00382 81 VLILDEITslldaeQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKD------LGPALLRRRFDRRIVL 144
|
|
| PRK07952 |
PRK07952 |
DNA replication protein DnaC; Validated |
101-187 |
1.73e-06 |
|
DNA replication protein DnaC; Validated
Pssm-ID: 181180 [Multi-domain] Cd Length: 244 Bit Score: 47.84 E-value: 1.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 101 VFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFE--AKADNSYHRKLKYYLAPDLLILDELGFKQLSDNIVD 178
Cdd:PRK07952 103 IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDtfSNSETSEEQLLNDLSNVDLLVIDEIGVQTESRYEKV 182
|
....*....
gi 1160634253 179 LFYEIISKR 187
Cdd:PRK07952 183 IINQIVDRR 191
|
|
| PhoH |
pfam02562 |
PhoH-like protein; PhoH is a cytoplasmic protein and predicted ATPase that is induced by ... |
92-125 |
5.06e-06 |
|
PhoH-like protein; PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.
Pssm-ID: 460592 [Multi-domain] Cd Length: 204 Bit Score: 45.94 E-value: 5.06e-06
10 20 30
....*....|....*....|....*....|....*..
gi 1160634253 92 EYIR--KKENIVF-VGPPGTGKTHLSISLGIKALQQG 125
Cdd:pfam02562 10 RYVEaiKKNDIVFgIGPAGTGKTYLAVAMAVDALKNG 46
|
|
| PRK06921 |
PRK06921 |
hypothetical protein; Provisional |
92-235 |
8.35e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 180750 [Multi-domain] Cd Length: 266 Bit Score: 45.93 E-value: 8.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 92 EYIRKKEN--IVFVGPPGTGKTHLSISLGIKALQQ-GYKVLFTSISEMMETLfeaKAD-NSYHRKLKYYLAPDLLILDEL 167
Cdd:PRK06921 110 EKIQESRKnsIALLGQPGSGKTHLLTAAANELMRKkGVPVLYFPFVEGFGDL---KDDfDLLEAKLNRMKKVEVLFIDDL 186
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160634253 168 -----GFKQLSDNIVDLFYEIISKRY-ETGSVIITSNKSFDDWGSIfhDRILATaildRIVHHC--HLILIKGDSF 235
Cdd:PRK06921 187 fkpvnGKPRATEWQIEQMYSVLNYRYlNHKPILISSELTIDELLDI--DEALGS----RIVEMCkdYLVIIKGDSF 256
|
|
| Bac_DnaA |
pfam00308 |
Bacterial dnaA protein; |
96-220 |
2.74e-05 |
|
Bacterial dnaA protein;
Pssm-ID: 278724 [Multi-domain] Cd Length: 219 Bit Score: 43.86 E-value: 2.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 96 KKENIVFV-GPPGTGKTHL--SISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDELGFKQL 172
Cdd:pfam00308 32 KAYNPLFIyGGVGLGKTHLlhAIGNYALQNAPNLRVVYLTAEEFLNDFVDAIRDNKTNQFKEKYRNVDVLLIDDIQFLAG 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160634253 173 SDNIVDLFYEIISKRYETG-SVIITSNKS------FDD-------WGSIFH----DRILATAILDR 220
Cdd:pfam00308 112 KEGTQEEFFHTFNALHESGkQIVFSSDRPpkeleeLEDrlrsrfqWGLVTDieppDLETRLAILRK 177
|
|
| DnaA |
COG0593 |
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair]; |
96-212 |
4.38e-05 |
|
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
Pssm-ID: 440358 [Multi-domain] Cd Length: 303 Bit Score: 43.64 E-value: 4.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 96 KKENIVFV-GPPGTGKTHL--SISLGIKALQQGYKVLFTSISEMMETLFEAKADNSYHRKLKYYLAPDLLILDELGFKQL 172
Cdd:COG0593 32 KAYNPLFLyGGVGLGKTHLlhAIGNEALENNPGARVVYLTAEEFTNDFINAIRNNTIEEFKEKYRSVDVLLIDDIQFLAG 111
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1160634253 173 SDNIVDLFYEIISKRYETG-SVIITSNKSFDDWGSIfHDRI 212
Cdd:COG0593 112 KEATQEEFFHTFNALREAGkQIVLTSDRPPKELPGL-EERL 151
|
|
| DEXXQc_SF1 |
cd18043 |
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ... |
94-132 |
1.74e-04 |
|
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350801 [Multi-domain] Cd Length: 127 Bit Score: 40.26 E-value: 1.74e-04
10 20 30
....*....|....*....|....*....|....*....
gi 1160634253 94 IRKKENIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTS 132
Cdd:cd18043 11 ARNGKNVVIQGPPGTGKSQTIANIIANALARGKRVLFVS 49
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
100-132 |
2.12e-04 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 39.91 E-value: 2.12e-04
10 20 30
....*....|....*....|....*....|....*.
gi 1160634253 100 IVFV-GPPGTGKTHLSISLGIKALQQ--GYKVLFTS 132
Cdd:cd17934 1 ISLIqGPPGTGKTTTIAAIVLQLLKGlrGKRVLVTA 36
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
97-222 |
2.75e-04 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 40.23 E-value: 2.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 97 KENIVFV-GPPGTGKTHLSISLgIKALQQ-GYKVLFTSIS-----EMMET----------LFEAKADNSYHRKLKYYLAP 159
Cdd:cd17933 11 RNRVSVLtGGAGTGKTTTLKAL-LAALEAeGKRVVLAAPTgkaakRLSEStgieastihrLLGINPGGGGFYYNEENPLD 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160634253 160 -DLLILDELGfkqLSDniVDLFYEIISKRYETGSVIITSnksfD-------DWGSIFHDRILA----TAILDRIV 222
Cdd:cd17933 90 aDLLIVDEAS---MVD--TRLMAALLSAIPAGARLILVG----DpdqlpsvGAGNVLRDLIASkgvpTVELTEVF 155
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
104-130 |
2.75e-04 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 41.00 E-value: 2.75e-04
10 20
....*....|....*....|....*..
gi 1160634253 104 GPPGTGKTHLSISLGIKALQQGYKVLF 130
Cdd:PRK09361 30 GPPGSGKTNICLQLAVEAAKNGKKVIY 56
|
|
| DEXXQc_SMUBP2 |
cd18044 |
DEXXQ-box helicase domain of SMUBP2; SMUBP2 (also called immunoglobulin mu-binding protein 2, ... |
104-134 |
4.06e-04 |
|
DEXXQ-box helicase domain of SMUBP2; SMUBP2 (also called immunoglobulin mu-binding protein 2, or IGHMBP2) is a 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. It is a DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence (5'-GGGCT-3') related to the immunoglobulin mu chain switch region. The IGHMBP2 gene is responsible for Charcot-Marie-Tooth disease (CMT) type 2S and spinal muscular atrophy with respiratory distress type 1 (SMARD1). It is also thought to play a role in frontotemporal dementia (FTD) with amyotrophic lateral sclerosis (ALS) and major depressive disorder (MDD). SMUBP2 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350802 [Multi-domain] Cd Length: 191 Bit Score: 40.29 E-value: 4.06e-04
10 20 30
....*....|....*....|....*....|.
gi 1160634253 104 GPPGTGKTHLSISLGIKALQQGYKVLFTSIS 134
Cdd:cd18044 24 GPPGTGKTTTVVEIILQAVKRGEKVLACAPS 54
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
19-130 |
1.01e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 40.01 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 19 TFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYD--FNFQPKLNR--QEIYNLATGEYI 94
Cdd:COG1061 18 LLLLDLERLELSLLRNLVEARRLAIKEGTREDGRRLPEEDTERELAEAEALEAGDeaSGTSFELRPyqQEALEALLAALE 97
|
90 100 110
....*....|....*....|....*....|....*.
gi 1160634253 95 RKKENIVFVGPPGTGKTHLSISLgIKALQQGYKVLF 130
Cdd:COG1061 98 RGGGRGLVVAPTGTGKTVLALAL-AAELLRGKRVLV 132
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
102-197 |
1.06e-03 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 39.22 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 102 FVGPPGTGKTHLSISLGIKALQQGYKVLFTS--------ISEMMETLFEAKADNSYhrklkyylapdllILDELGFKQLS 173
Cdd:cd01394 24 IYGPPGSGKTNICLQLAVEAAKQGKKVVYIDteglsperFQQIAGERFESIASNII-------------VFEPYSFDEQG 90
|
90 100
....*....|....*....|....
gi 1160634253 174 DNIVDLfyEIISKRYETGSVIITS 197
Cdd:cd01394 91 VAIQEA--EKLLKSDKVDLVVVDS 112
|
|
| PhoH |
COG1702 |
Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; ... |
94-125 |
1.29e-03 |
|
Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms];
Pssm-ID: 441308 [Multi-domain] Cd Length: 325 Bit Score: 39.27 E-value: 1.29e-03
10 20 30
....*....|....*....|....*....|...
gi 1160634253 94 IRKKEnIVF-VGPPGTGKTHLSISLGIKALQQG 125
Cdd:COG1702 125 IRKND-IVFgIGPAGTGKTYLAVAMAVAALKRG 156
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
100-167 |
1.46e-03 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 37.57 E-value: 1.46e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160634253 100 IVFVGPPGTGKTHLsislgIKAL--QQGYKVLFTSISEMMETLFEAKADN-----SYHRKlkyyLAPDLLILDEL 167
Cdd:pfam00004 1 LLLYGPPGTGKTTL-----AKAVakELGAPFIEISGSELVSKYVGESEKRlrelfEAAKK----LAPCVIFIDEI 66
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
16-113 |
2.08e-03 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 38.98 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 16 VAKTFEIRNEQAIKEKLSYLEFFELLIEDEMSNRKDNSYKKRTAKAKFPSIKTLEEYDFNFQPKLNRQEIYNLATGEYI- 94
Cdd:COG1401 136 RLLLELADLEERAALETEVLEALEAELEELLAAPEDLSADALAAELSAAEELYSEDLESEDDYLKDLLREKFEETLEAFl 215
|
90 100
....*....|....*....|..
gi 1160634253 95 ---RKKENIVFVGPPGTGKTHL 113
Cdd:COG1401 216 aalKTKKNVILAGPPGTGKTYL 237
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
99-142 |
2.70e-03 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 37.97 E-value: 2.70e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1160634253 99 NIVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFE 142
Cdd:COG0467 22 STLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEQLLR 65
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
100-221 |
5.32e-03 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 35.94 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160634253 100 IVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSISEMMETLFEAKADNsyhrklkyyLAPDLLILDELGF------KQLS 173
Cdd:cd01120 1 ILITGPPGSGKTTLLLQFAEQALLSDEPVIFISFLDTILEAIEDLIEE---------KKLDIIIIDSLSSlarasqGDRS 71
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1160634253 174 DNIVDLFYEIISKRYETGSVIITSNKSfDDWGSIFHDRILATAILDRI 221
Cdd:cd01120 72 SELLEDLAKLLRAARNTGITVIATIHS-DKFDIDRGGSSNDERLLKSL 118
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
94-122 |
6.36e-03 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 36.11 E-value: 6.36e-03
10 20
....*....|....*....|....*....
gi 1160634253 94 IRKKENIVFVGPPGTGKTHLsislgIKAL 122
Cdd:cd19481 23 LGLPKGILLYGPPGTGKTLL-----AKAL 46
|
|
| ArsA |
COG0003 |
Anion-transporting ATPase, ArsA/GET3 family [Inorganic ion transport and metabolism]; |
100-133 |
8.77e-03 |
|
Anion-transporting ATPase, ArsA/GET3 family [Inorganic ion transport and metabolism];
Pssm-ID: 439774 Cd Length: 299 Bit Score: 36.72 E-value: 8.77e-03
10 20 30
....*....|....*....|....*....|....
gi 1160634253 100 IVFVGPPGTGKTHLSISLGIKALQQGYKVLFTSI 133
Cdd:COG0003 6 IFFTGKGGVGKTTVAAATALALAERGKRTLLVST 39
|
|
| DEXSMc_CoV_Nsp13 |
cd22649 |
DEXSM-box helicase domain of coronavirus Nsp13 helicase; Helicases catalyze the NTP-dependent ... |
73-134 |
9.22e-03 |
|
DEXSM-box helicase domain of coronavirus Nsp13 helicase; Helicases catalyze the NTP-dependent unwinding of nucleic acid duplexes into single strands and are classified into six superfamilies based on the arrangement of conserved motifs. This family contains coronavirus (CoV) non-structural protein 13 (Nsp13) helicase, including those from highly pathogenic human betaCoVs such as Severe Acute Respiratory Syndrome coronavirus (SARS) and SARS-CoV-2 (also known as 2019 novel CoV (2019-nCoV) or COVID-19 virus). Nsp13 helicase is a component of the viral RNA synthesis replication and transcription complex (RTC). SARS-Nsp13 is strongly inhibited by natural flavonoids, myricetin and scutellarein, and is emerging as a target for development of anti-SARS medications. It contains an N-terminal Cys/His rich zinc-binding domain (CH/ZBD), a stalk domain, a 1B regulatory domain, and an SF1 helicase core that carries a DEAD-box helicase domain. Nsp13 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438713 [Multi-domain] Cd Length: 202 Bit Score: 36.22 E-value: 9.22e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1160634253 73 DFNFQPKLNRQEIY--NLATGEYIRKKENIVFVGPPGTGKTHLSISLGIkaLQQGYKVLFTSIS 134
Cdd:cd22649 8 ITGLYPTLNVPEEFsnNVPNYQKIGMQKYTTVQGPPGTGKSHFAIGLAL--YYPSARVVYTACS 69
|
|
| |
