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Conserved domains on  [gi|1172358694|ref|WP_080741965|]
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MULTISPECIES: class I SAM-dependent methyltransferase [Burkholderia]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10612269)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Mycolicibacterium hassiacum MMP 1-O-methyltransferase

CATH:  3.40.50.150
EC:  2.1.1.-
Gene Ontology:  GO:1904047|GO:0008168|GO:0032259|GO:0008757
PubMed:  12826405|12504684
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_24 pfam13578
Methyltransferase domain; This family appears to be a methyltransferase domain.
 106-158 3.39e-10

Methyltransferase domain; This family appears to be a methyltransferase domain.


:

Pssm-ID: 433324 [Multi-domain]  Cd Length: 106  Bit Score: 55.01  E-value: 3.39e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1172358694 106 HEGLSSETLPRYPDEYFDMIYIDAAHTFDEVKLDAEISAAKIKKDGVLIFNDY 158
Cdd:pfam13578  54 IVGDSREALPSLADGPIDLLFIDGDHTYEAVLNDLELWLPRLAPGGVILFHDI 106
 
Name Accession Description Interval E-value
Methyltransf_24 pfam13578
Methyltransferase domain; This family appears to be a methyltransferase domain.
 106-158 3.39e-10

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 433324 [Multi-domain]  Cd Length: 106  Bit Score: 55.01  E-value: 3.39e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1172358694 106 HEGLSSETLPRYPDEYFDMIYIDAAHTFDEVKLDAEISAAKIKKDGVLIFNDY 158
Cdd:pfam13578  54 IVGDSREALPSLADGPIDLLFIDGDHTYEAVLNDLELWLPRLAPGGVILFHDI 106
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 106-182 4.68e-07

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 47.87  E-value: 4.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172358694 106 HEGLSSETLPRYPDEYFDMIYIDAAHtfDEVKLDAEISAAKIKKDGVLIFNDYIMHDPFI-----HADYGIVPVVNEMVV 180
Cdd:COG4122    73 ILGDALEVLPRLADGPFDLVFIDADK--SNYPDYLELALPLLRPGGLIVADNVLWHGRVAdparrDPSTRAIREFNEYLR 150


                  ..
gi 1172358694 181 NH 182
Cdd:COG4122   151 ED 152
 
Name Accession Description Interval E-value
Methyltransf_24 pfam13578
Methyltransferase domain; This family appears to be a methyltransferase domain.
 106-158 3.39e-10

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 433324 [Multi-domain]  Cd Length: 106  Bit Score: 55.01  E-value: 3.39e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1172358694 106 HEGLSSETLPRYPDEYFDMIYIDAAHTFDEVKLDAEISAAKIKKDGVLIFNDY 158
Cdd:pfam13578  54 IVGDSREALPSLADGPIDLLFIDGDHTYEAVLNDLELWLPRLAPGGVILFHDI 106
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 106-182 4.68e-07

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 47.87  E-value: 4.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1172358694 106 HEGLSSETLPRYPDEYFDMIYIDAAHtfDEVKLDAEISAAKIKKDGVLIFNDYIMHDPFI-----HADYGIVPVVNEMVV 180
Cdd:COG4122    73 ILGDALEVLPRLADGPFDLVFIDADK--SNYPDYLELALPLLRPGGLIVADNVLWHGRVAdparrDPSTRAIREFNEYLR 150


                  ..
gi 1172358694 181 NH 182
Cdd:COG4122   151 ED 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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