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Conserved domains on  [gi|1174825017|ref|WP_081506853|]
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hypothetical protein [Roseovarius mucosus]

Protein Classification

HicB family protein( domain architecture ID 10008903)

uncharacterized protein similar to Yersinia pestis antitoxin HicB3, which neutralizes the toxin RNAse HicA3 by blocking its active site, and it represses transcription of the hicA3B3 operon

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4877 COG4877
Uncharacterized conserved protein [Function unknown];
6-62 2.41e-12

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443905  Cd Length: 62  Bit Score: 54.91  E-value: 2.41e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1174825017  6 KTAQVNLRIRPELKEAAERAASEDQRSLTSLVEKLLTDHLREKGYLSKVGGETPDAE 62
Cdd:COG4877    3 KKKQFLLRIDPALYEALERWAADELRSVNAQIEYLLREALRKAGRLPKKKRTEPRRG 59
 
Name Accession Description Interval E-value
COG4877 COG4877
Uncharacterized conserved protein [Function unknown];
6-62 2.41e-12

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443905  Cd Length: 62  Bit Score: 54.91  E-value: 2.41e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1174825017  6 KTAQVNLRIRPELKEAAERAASEDQRSLTSLVEKLLTDHLREKGYLSKVGGETPDAE 62
Cdd:COG4877    3 KKKQFLLRIDPALYEALERWAADELRSVNAQIEYLLREALRKAGRLPKKKRTEPRRG 59
 
Name Accession Description Interval E-value
COG4877 COG4877
Uncharacterized conserved protein [Function unknown];
6-62 2.41e-12

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443905  Cd Length: 62  Bit Score: 54.91  E-value: 2.41e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1174825017  6 KTAQVNLRIRPELKEAAERAASEDQRSLTSLVEKLLTDHLREKGYLSKVGGETPDAE 62
Cdd:COG4877    3 KKKQFLLRIDPALYEALERWAADELRSVNAQIEYLLREALRKAGRLPKKKRTEPRRG 59
HicB COG4226
Predicted nuclease of the RNAse H fold, HicB family [General function prediction only];
9-48 2.67e-03

Predicted nuclease of the RNAse H fold, HicB family [General function prediction only];


Pssm-ID: 443370 [Multi-domain]  Cd Length: 110  Bit Score: 32.85  E-value: 2.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1174825017   9 QVNLRIRPELKEAAERAASEDQRSLTSLVEKLLTDHLREK 48
Cdd:COG4226    71 KFNVRIPPELHRALAIAAAEEGVSLNQWVVEALSEALAHE 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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