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Conserved domains on  [gi|1181370062|ref|WP_084669882|]
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N-acetyltransferase [Duganella zoogloeoides]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11418877)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 88-173 3.74e-14

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 65.06  E-value: 3.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  88 GHIDLRANPEPFAAHrcLLGMGVDRTLRKFGLGQRLIEHAGKWASESGkVKWIDLQVLSVNQPAIRLYERSGFTKTGEVP 167
Cdd:COG0456     1 GFALLGLVDGGDEAE--IEDLAVDPEYRGRGIGRALLEAALERARERG-ARRLRLEVREDNEAAIALYEKLGFEEVGERP 77


                  ....*.
gi 1181370062 168 EMFEID 173
Cdd:COG0456    78 NYYGDD 83
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 88-173 3.74e-14

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 65.06  E-value: 3.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  88 GHIDLRANPEPFAAHrcLLGMGVDRTLRKFGLGQRLIEHAGKWASESGkVKWIDLQVLSVNQPAIRLYERSGFTKTGEVP 167
Cdd:COG0456     1 GFALLGLVDGGDEAE--IEDLAVDPEYRGRGIGRALLEAALERARERG-ARRLRLEVREDNEAAIALYEKLGFEEVGERP 77


                  ....*.
gi 1181370062 168 EMFEID 173
Cdd:COG0456    78 NYYGDD 83
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 74-160 8.91e-11

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 56.76  E-value: 8.91e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  74 RRLWGAFTPGrKLVGHIDLRANPEPFAaHRCLLGMGVDRTLRKFGLGQRLIEHAGKWASESGKVKwIDLQVLSVNQPAIR 153
Cdd:pfam00583  33 EGFFVAEEDG-ELVGFASLSIIDDEPP-VGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCER-IFLEVAADNLAAIA 109


                  ....*..
gi 1181370062 154 LYERSGF 160
Cdd:pfam00583 110 LYEKLGF 116
PRK03624 PRK03624
putative acetyltransferase; Provisional
 109-161 2.18e-05

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 42.61  E-value: 2.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1181370062 109 GVDRTLRKFGLGQRLIEHAGKWASESGKVKwIDLQVLSVNQPAIRLYERSGFT 161
Cdd:PRK03624   75 AVHPDFRGRGIGRALVARLEKKLIARGCPK-INLQVREDNDAVLGFYEALGYE 126
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 88-173 3.74e-14

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 65.06  E-value: 3.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  88 GHIDLRANPEPFAAHrcLLGMGVDRTLRKFGLGQRLIEHAGKWASESGkVKWIDLQVLSVNQPAIRLYERSGFTKTGEVP 167
Cdd:COG0456     1 GFALLGLVDGGDEAE--IEDLAVDPEYRGRGIGRALLEAALERARERG-ARRLRLEVREDNEAAIALYEKLGFEEVGERP 77


                  ....*.
gi 1181370062 168 EMFEID 173
Cdd:COG0456    78 NYYGDD 83
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 10-175 4.61e-14

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 66.95  E-value: 4.61e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  10 VAIEPIASSAFEVFFAYLNDhlsdngkPGNVYFQPLPYaesvFSIDKAKAFRDALDIPMGEPGWRRLWGAFTPGRKLVGH 89
Cdd:COG1670     8 LRLRPLRPEDAEALAELLND-------PEVARYLPGPP----YSLEEARAWLERLLADWADGGALPFAIEDKEDGELIGV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  90 IDLRanPEPFAAHRCLLGMGVDRTLRKFGLGQRLIEHAGKWASESGKVKWIDLQVLSVNQPAIRLYERSGFTKTGEVPEM 169
Cdd:COG1670    77 VGLY--DIDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDA 154


                  ....*.
gi 1181370062 170 FEIDGQ 175
Cdd:COG1670   155 LVIDGR 160
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
67-185 3.21e-13

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 64.25  E-value: 3.21e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  67 PMGEPGWRRLWGAFTPGR----------KLVGHIDLRAN-PEPFAAHRCLLGMGVDRTLRKFGLGQRLIEHAGKWASESG 135
Cdd:COG1247    34 PPSEEEREAWFAAILAPGrpvlvaeedgEVVGFASLGPFrPRPAYRGTAEESIYVDPDARGRGIGRALLEALIERARARG 113

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1181370062 136 kVKWIDLQVLSVNQPAIRLYERSGFTKTGEVPEMFEIDGQPFSYTSMAKR 185
Cdd:COG1247   114 -YRRLVAVVLADNEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQKR 162
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 85-169 3.74e-12

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 60.84  E-value: 3.74e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  85 KLVGHIDLRANPEPfaaHRCLLGMGVDRTLRKFGLGQRLIEHAGKWASESGkVKWIDLQVLSVNQPAIRLYERSGFTKTG 164
Cdd:COG0454    44 EPIGFAGLRRLDDK---VLELKRLYVLPEYRGKGIGKALLEALLEWARERG-CTALELDTLDGNPAAIRFYERLGFKEIE 119


                  ....*
gi 1181370062 165 EVPEM 169
Cdd:COG0454   120 RYVAY 124
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 74-160 8.91e-11

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 56.76  E-value: 8.91e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  74 RRLWGAFTPGrKLVGHIDLRANPEPFAaHRCLLGMGVDRTLRKFGLGQRLIEHAGKWASESGKVKwIDLQVLSVNQPAIR 153
Cdd:pfam00583  33 EGFFVAEEDG-ELVGFASLSIIDDEPP-VGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCER-IFLEVAADNLAAIA 109


                  ....*..
gi 1181370062 154 LYERSGF 160
Cdd:pfam00583 110 LYEKLGF 116
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 73-162 9.00e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 53.23  E-value: 9.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  73 WRRLWGAFTPGrKLVGHIDLRanPEPFAAHRCLLGMGVDRTLRKFGLGQRLIEHAGKWASESGkvkwIDLQVLSVNQPAI 152
Cdd:pfam13508   2 GGRFFVAEDDG-KIVGFAALL--PLDDEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGG----IKLLELETTNRAA 74

                          90
                  ....*....|
gi 1181370062 153 RLYERSGFTK 162
Cdd:pfam13508  75 AFYEKLGFEE 84
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
85-170 2.03e-09

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 52.22  E-value: 2.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  85 KLVGHIDLRANPEPFAAhrcLLGMGVDRTLRKFGLGQRLIEHAGKWASESGkVKWIDLQVLSVNQPAIRLYERSGFTKTG 164
Cdd:COG3393     1 ELVAMAGVRAESPGVAE---ISGVYTHPEYRGRGLASALVAALAREALARG-ARTPFLYVDADNPAARRLYERLGFRPVG 76


                  ....*.
gi 1181370062 165 EVPEMF 170
Cdd:COG3393    77 EYATVL 82
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
85-165 6.89e-08

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 49.31  E-value: 6.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  85 KLVGHIDLRANPEPFAAHRCLLG-MGVDRTLRKFGLGQRLIEHAGKWASESGkvkwIDLQVLSVNQPAIRLYERSGFTKT 163
Cdd:COG3153    49 EIVGHVALSPVDIDGEGPALLLGpLAVDPEYRGQGIGRALMRAALEAARERG----ARAVVLLGDPSLLPFYERFGFRPA 124


                  ..
gi 1181370062 164 GE 165
Cdd:COG3153   125 GE 126
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 76-185 1.92e-07

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 48.04  E-value: 1.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  76 LWGAFTpGRKLVGHIDLRANPepfaaHRCLLGmgVDRTLRKFGLGQRLIEHAGKWASESGkvkwIDLQVLSVN-QP-AIR 153
Cdd:pfam13673  33 FFVAFE-GGQIVGVIALRDRG-----HISLLF--VDPDYQGQGIGKALLEAVEDYAEKDG----IKLSELTVNaSPyAVP 100

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1181370062 154 LYERSGFTKTGevpEMFEIDGqpFSYTSMAKR 185
Cdd:pfam13673 101 FYEKLGFRATG---PEQEFNG--IRFVPMEKE 127
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 70-165 6.32e-07

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 46.52  E-value: 6.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  70 EPGWRRLWGAFTPGrKLVGHIDLRANPEPFAAHRCllgMGVDRTLRKFGLGQRLIEHAGKWASESGkVKWIdlqVLSVNQ 149
Cdd:COG1246    24 EEEIGEFWVAEEDG-EIVGCAALHPLDEDLAELRS---LAVHPDYRGRGIGRRLLEALLAEARELG-LKRL---FLLTTS 95

                          90
                  ....*....|....*.
gi 1181370062 150 PAIRLYERSGFTKTGE 165
Cdd:COG1246    96 AAIHFYEKLGFEEIDK 111
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
108-187 1.79e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 45.56  E-value: 1.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062 108 MGVDRTLRKFGLGQRLIEHAGKWASESGKVK-WIDLQVlsvnqPAIRLYERSGFTKTGEVpemFEIDGQPfsYTSMAKRV 186
Cdd:COG2153    64 VAVLPEYRGQGLGRALMEAAIEEARERGARRiVLSAQA-----HAVGFYEKLGFVPVGEE---FLEAGIP--HIDMRKPL 133


                  .
gi 1181370062 187 E 187
Cdd:COG2153   134 S 134
PRK03624 PRK03624
putative acetyltransferase; Provisional
 109-161 2.18e-05

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 42.61  E-value: 2.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1181370062 109 GVDRTLRKFGLGQRLIEHAGKWASESGKVKwIDLQVLSVNQPAIRLYERSGFT 161
Cdd:PRK03624   75 AVHPDFRGRGIGRALVARLEKKLIARGCPK-INLQVREDNDAVLGFYEALGYE 126
PRK10140 PRK10140
N-acetyltransferase;
86-164 1.66e-03

N-acetyltransferase;


Pssm-ID: 182263 [Multi-domain]  Cd Length: 162  Bit Score: 37.65  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1181370062  86 LVGHIDLRANPEPFAAHRCLLGMGVDRTLRKFGLGQRL----IEHAGKWAsesgKVKWIDLQVLSVNQPAIRLYERSGFT 161
Cdd:PRK10140   62 VVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALmremIEMCDNWL----RVDRIELTVFVDNAPAIKVYKKYGFE 137


                  ...
gi 1181370062 162 KTG 164
Cdd:PRK10140  138 IEG 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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