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Conserved domains on  [gi|1189288138|ref|WP_085708060|]
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TonB-dependent siderophore receptor [Pseudomonas savastanoi]

Protein Classification

TonB-dependent receptor plug domain-containing protein( domain architecture ID 11469150)

TonB-dependent receptor plug domain-containing protein may act as a TonB-dependent siderophore receptor, a channel to allow import of iron-siderophore complexes; similar to Escherichia coli ferrienterobactin receptor, which is involved in the initial step of iron uptake by binding ferrienterobactin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
18-757 2.41e-77

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


:

Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 262.10  E-value: 2.41e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  18 LLSVACISASAHAAQATDEQNSQgASTLSTVIVTGTRaQERTASASLSPIDVISGDSLRSSGSSELGTVLaRLIPSINFP 97
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAED-ATELEEVVVTATR-TEQSLSDAPASVSVITAEEIEKLGATDLADAL-RLLPGVSVT 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  98 RPSLVDGaelTRPAQLRGLSPDQVLVLVlvlvlvNGKRRHTSAFvnlggavgrgSAPADLNAIPLSAIDHIEVLRDGASA 177
Cdd:COG4771    78 RSGGRGG---SSGISIRGLGGDRVLVLI------DGVPVNNPAL----------GGGGDLSYIPPDDIERIEVIRGPASA 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 178 RYGSDAIAGVINIILKSADH--GGSISSKYGQYKKGdgiQRQVSGNTGFAlGDNGTLNLSGEGSNNDYTNRAGDDFRTSS 255
Cdd:COG4771   139 LYGSDAIGGVINIITKKPTDelEGSVSLGYGSNGNG---TYSGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGGFVGN 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 256 IGSTTYgqqvfrqgepqthegKLQYNAEYSFNDAAEFYSFGGYSKRRGEtaafyrpSNASNNIAAIYPNGYLPLINGTLE 335
Cdd:COG4771   215 SGYERY---------------NLNAKLGYRLSDNHRLSLSGGYSRQDRD-------GGPPTLGDTEISSDNAGDRDTTTD 272
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 336 DTSLVAGLRGELADDWhyDVSANYGKNtyelrtkTINTSLGLNTPRSFDNGTLTNDQKQLGFDLSREFSAAWlphpvSVS 415
Cdd:COG4771   273 RGNYSLRYNGDLGDNL--DLSLYYSRT-------DRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNH-----TLT 338
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 416 FGAEYLHQGYQIEagqaesyfqtgssglggfRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFG----SNV 491
Cdd:COG4771   339 LGAEYRYDDLDSS------------------SFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAF 400
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 492 SGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFTFTssqligntiqeagtfpaGSNVAQLLGAEDLKPEKSRNYSLSLV 571
Cdd:COG4771   401 SPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGT-----------------GTPGRYVLGNPDLKPETSDNYELGLE 463
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 572 LQPLD-SLTVTADVYRIDIQDRISLSSNlvlnntainylrsngvgDINYTSARYFTNATDTSTDGVDLVANYRYqfdnGV 650
Cdd:COG4771   464 YRLGNgGLSLSLTGFYTDIKDLIVLVPV-----------------GPGPGDVLQYENVGKARTYGLELELKYRL----GK 522
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 651 RWNSTVGYNYNHTKVTDVKANPAIldqlgvnlvrvdrrerigllgDTTPQHKLTLGNDLTFGNWALHSNLVRYGEFTSYQ 730
Cdd:COG4771   523 GLTLTASYTYLDSKIDDGDTGEPL---------------------PNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVT 581
                         730       740
                  ....*....|....*....|....*...
gi 1189288138 731 A-DKVKDQTFSAAWLLDLAVDYTLKNWV 757
Cdd:COG4771   582 PpSGRLEGYTPGYTLLDLRASYKLTKNL 609
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
18-757 2.41e-77

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 262.10  E-value: 2.41e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  18 LLSVACISASAHAAQATDEQNSQgASTLSTVIVTGTRaQERTASASLSPIDVISGDSLRSSGSSELGTVLaRLIPSINFP 97
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAED-ATELEEVVVTATR-TEQSLSDAPASVSVITAEEIEKLGATDLADAL-RLLPGVSVT 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  98 RPSLVDGaelTRPAQLRGLSPDQVLVLVlvlvlvNGKRRHTSAFvnlggavgrgSAPADLNAIPLSAIDHIEVLRDGASA 177
Cdd:COG4771    78 RSGGRGG---SSGISIRGLGGDRVLVLI------DGVPVNNPAL----------GGGGDLSYIPPDDIERIEVIRGPASA 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 178 RYGSDAIAGVINIILKSADH--GGSISSKYGQYKKGdgiQRQVSGNTGFAlGDNGTLNLSGEGSNNDYTNRAGDDFRTSS 255
Cdd:COG4771   139 LYGSDAIGGVINIITKKPTDelEGSVSLGYGSNGNG---TYSGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGGFVGN 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 256 IGSTTYgqqvfrqgepqthegKLQYNAEYSFNDAAEFYSFGGYSKRRGEtaafyrpSNASNNIAAIYPNGYLPLINGTLE 335
Cdd:COG4771   215 SGYERY---------------NLNAKLGYRLSDNHRLSLSGGYSRQDRD-------GGPPTLGDTEISSDNAGDRDTTTD 272
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 336 DTSLVAGLRGELADDWhyDVSANYGKNtyelrtkTINTSLGLNTPRSFDNGTLTNDQKQLGFDLSREFSAAWlphpvSVS 415
Cdd:COG4771   273 RGNYSLRYNGDLGDNL--DLSLYYSRT-------DRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNH-----TLT 338
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 416 FGAEYLHQGYQIEagqaesyfqtgssglggfRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFG----SNV 491
Cdd:COG4771   339 LGAEYRYDDLDSS------------------SFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAF 400
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 492 SGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFTFTssqligntiqeagtfpaGSNVAQLLGAEDLKPEKSRNYSLSLV 571
Cdd:COG4771   401 SPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGT-----------------GTPGRYVLGNPDLKPETSDNYELGLE 463
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 572 LQPLD-SLTVTADVYRIDIQDRISLSSNlvlnntainylrsngvgDINYTSARYFTNATDTSTDGVDLVANYRYqfdnGV 650
Cdd:COG4771   464 YRLGNgGLSLSLTGFYTDIKDLIVLVPV-----------------GPGPGDVLQYENVGKARTYGLELELKYRL----GK 522
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 651 RWNSTVGYNYNHTKVTDVKANPAIldqlgvnlvrvdrrerigllgDTTPQHKLTLGNDLTFGNWALHSNLVRYGEFTSYQ 730
Cdd:COG4771   523 GLTLTASYTYLDSKIDDGDTGEPL---------------------PNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVT 581
                         730       740
                  ....*....|....*....|....*...
gi 1189288138 731 A-DKVKDQTFSAAWLLDLAVDYTLKNWV 757
Cdd:COG4771   582 PpSGRLEGYTPGYTLLDLRASYKLTKNL 609
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
66-806 2.25e-66

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 232.73  E-value: 2.25e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  66 PIDVISGDSLRSSGSSELGTVLARlIPSINFPRpslvDGAELTRPAQLRGLSPDQVLVLVlvlvlvNGKRRHTSafvnlg 145
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRR-IPGVSVTR----GGGGGGSTISIRGFGPDRTLVLV------DGLPLASS------ 63
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 146 gavgRGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSADH--GGSISSKYGQYKKGDGIQRQVSGNTG 223
Cdd:cd01347    64 ----NYGRGVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGGGFDVSGA 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 224 FALGDNGTLNLSGegsnndyTNRAGDDFRTSSIGSTTYGQQVfrqgepQTHEGKLQYNaeysFNDAAEFYSFGGYSKRRG 303
Cdd:cd01347   140 LADDGAFGARLYG-------AYRDGDGTIDGDGQADDSDEER------YNVAGKLDWR----PDDDTRLTLDAGYQDQDA 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 304 ETA----AFYRPSNASNNIAAIYPNGYLPLINGTLEDTSLVAGLRGELADDWH-YDVSANYGKNTYELRTKTINTSLGLN 378
Cdd:cd01347   203 DGPggtlPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGWtLRANLSYSYTDNDGDPLILNGGNNAA 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 379 TPRSFDNGTLTN-DQKQLGFDLSREFSAAWLPHPVSVSFGAEYLHQgyqieagqaesyfqtgssglggfraadagSYSRH 457
Cdd:cd01347   283 GGDLGRSGYSSErDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRRE-----------------------------ELDEK 333
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 458 NFAQYLDVETNLTEKLGVSAAVRHEDY--------------SDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQ 523
Cdd:cd01347   334 QTALYAQDTIELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGEL 413
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 524 NFTFTSSqligntiqeagtfpagsnVAQLLGAEDLKPEKSRNYSLSLVLQPLDSLTVTADVYRIDIQDRISLSSNLVLNN 603
Cdd:cd01347   414 YGGGSHG------------------GTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLG 475
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 604 TAINYlrsngvgdinytsaryfTNATDTSTDGVDLVANYRyqFDNGVRWnsTVGYNYNHTKVTDVKANPAildqlgvnlv 683
Cdd:cd01347   476 LVTVY-----------------VNGGKARIRGVELEASYD--LTDGLGL--TGSYTYTDTEVKRTDGATT---------- 524
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 684 rvdrreriGLLGDTTPQHKLTLGND--LTFGNWALHSNLVRYGEFTSYQADKVKDQTFSAAWLLDLAVDYTL-KNWVFTL 760
Cdd:cd01347   525 --------GNRLPGIPKHTANLGLDyeLPDEGLTAGGGVRYRGKQYADTANGNNTVKVPGYTLVDLSASYQFtKNLTLRL 596
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*.
gi 1189288138 761 GGDNITDKypeklnDFSSSGGNLAYSTFSPYGYsGAFYYGKVTYNW 806
Cdd:cd01347   597 GVNNLFDK------DYYTSLSVRGSGLYGYYGP-GRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
279-785 1.35e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 126.42  E-value: 1.35e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 279 QYNAEYSFNDAAEFYSFGGYSKRRGETAAFYRPSNASNNIAAIYPNGYLPLINGTLEDTSLVAGLRGELADDWHYDVSAN 358
Cdd:pfam00593   3 QLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 359 YGKNTYELRTKTINTSLGLNTPRSFDNGTLTNDQKQLGFDLSREFSAAWlphpvSVSFGAEYLHQGYQIeagQAESYFQT 438
Cdd:pfam00593  83 LGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSH-----DLLLGVELRTAGLDY---RRLDDDAY 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 439 GSSGLGGFRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFGSN--------------VSGSLSARYDFTPQ 504
Cdd:pfam00593 155 DPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDN 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 505 VALRGSVSTGFRAPSLAQQNFTFTSsqligntiqeagtfpaGSNVAQLLGAEDLKPEKSRNYSLSLVLQPlDSLTVTADV 584
Cdd:pfam00593 235 LSLYASYSRGFRAPSLGELYGSGSG----------------GGGGAVAGGNPDLKPETSDNYELGLKYDD-GRLSLSLAL 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 585 YRIDIQDRISLSSNLVLNNTAINylrsngvgdinytsarYFTNATDTSTDGVDLVANYRyqfdngvRWNSTVGYN-YNHT 663
Cdd:pfam00593 298 FYIDIKNLITSDPDGPGLGGTVY----------------TYTNVGKARIRGVELELSGR-------LWGLGLSGGgYTYT 354
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 664 KVTDVKANPAILDQLgvnlvrvdrrerigllgDTTPQHKLTLGNDLTF--GNWALHSNLVRYGEFTSYQADKVKDQTFSA 741
Cdd:pfam00593 355 DADDDADADDTGNPL-----------------PNVPRHTANLGLTYDFplGGWGARLGARYVGSGERRYGDAANTFKTPG 417
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 1189288138 742 AWLLDLAVDYTL-KNWVFTLGGDNITDKYPEKLNDFSSSGGNLAY 785
Cdd:pfam00593 418 YTLVDLSAGYRLnKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYP 462
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
149-785 2.14e-24

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 109.04  E-value: 2.14e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 149 GRGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSAD---HGGSisSKYGQYKKG-DGIQRQVSGNTGF 224
Cdd:TIGR01786  89 GQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAAdllKPGK--DLGGLSKLGySSANNRFTQSVAA 166
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 225 AL-GDN------GTLNLSGEGSNNDYTNrAGDDFRTSSIGSTTYGQQVFRqgepqtheGKLQYnaeySFNDAAEFYSFGG 297
Cdd:TIGR01786 167 AGrNDDvdalvqATYRRGHELKNGNKAN-IGNESKRSKPNPSDYKSQSFL--------AKLGW----QLNDAHRLGLSLE 233
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 298 YSKRRGETAAFYRPSNASNNIAAIYPNGYLPLINGT--LEDTSLVAGLRGElaDDWHYDVSANYGKNTYELRTKTINTSL 375
Cdd:TIGR01786 234 YTQTDYDEPEMTNTSYLTKPLGAPLLSSTVVLGDSKtrDRRTGLDYELNPD--NSWLDTVKLALDKQYIQLYNYLNATSA 311
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 376 GlnTPRSFDNGTLTNDQKQ---LGFDLsrEFSAAWLPHPVSVSFGAEYLHQGYQIEAGQAEsyFQTGSSGLGGFRAaDAG 452
Cdd:TIGR01786 312 S--DYPGVDKNGRYKDKYDyytLGFDT--NNKIEFSVHSLSLTYGLDRFKDKVSTGDSRRN--LPTAAYNLYGYEG-ENR 384
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 453 SYSRHNFAQYLDVETNLTEKLGVSAAVR--------------HEDYSDFGSNV-SGSLSARYDFTPQVALRGSVSTGFRA 517
Cdd:TIGR01786 385 PVKGSNFGLFLQDNIKLGDWLSLSAGLRydhyktdpkadeskDYGAISKTYSRwSPSLGLTYKPTPWLTLYYSYSQGFRA 464
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 518 PSLAQQNFTFTssqligntiqeagtfPAGSNVAQLLGAEDLKPEKSRNYSLSLVLQpLDSLTVTADVYRIDIQDRISLSS 597
Cdd:TIGR01786 465 PSFDELYGTGA---------------HPGGGPYTFLPNPNLKPETSKNWEIGINLH-FDQLDFKVSYFRNDYKDFIDLGI 528
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 598 nlvLNNTAINYlrsNGVGDINYTSaryFTNATDTSTDGVDLVANYRYQFDNGVRWNSTVGYNYNHTKVTDVKANPAildq 677
Cdd:TIGR01786 529 ---GVTAKGNM---AQVGSNTITN---YVNIDNARIRGIELSGRYDLGSFFSGPDGWTTTLKYGYTKGKDSDTNPW---- 595
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 678 lgvnLVRVDRRERIGLLGDTTPQHKLTLGNDLTFgnWALHSNLVRYGEFTSYQADKVKDQTFSAAW-LLDLAVDYTL-KN 755
Cdd:TIGR01786 596 ----LNAITPLKVVLGLGYDHPDEKWGVGLTLTF--SGAKDAVDAYATYYENGEAAKAGPLRTPSYtVVDLYGYYKPnKN 669
                         650       660       670
                  ....*....|....*....|....*....|.
gi 1189288138 756 WVFTLGGDNITD-KYPEKLNDFSSSGGNLAY 785
Cdd:TIGR01786 670 LTLRFGVYNLLDrKYTTWESARQAGPLATGY 700
PRK13513 PRK13513
ligand-gated channel protein;
15-594 1.10e-23

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 106.78  E-value: 1.10e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  15 SANLLSVACISASAHAAQATDEqnsqgASTLSTVIVTGTRAQERTASASLSpIDVISGDSLRSSGSSELGTVLaRLIPSI 94
Cdd:PRK13513   10 KAALVIAAAISSQAYAAEKTNT-----ATPTDTMVVTASGFQQRIQDAPAS-ISVVTREQLENKAYRDVTDAL-KDVPGV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  95 nfprpsLVDGAELTRPAQLRGLSPdqvlvlVLVLVLVNGKRRHTsafvnlggavgRGSAP-ADLNAI------PLSAIDH 167
Cdd:PRK13513   83 ------VVTGGGSTSDISIRGMAA------KYTLILVDGKRVDT-----------RSTRPnSDGSGIeqgwlpPLAAIER 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 168 IEVLRDGASARYGSDAIAGVINIILKSADHG--GSISSKYG-QYKKGDGIQRQVSGNTGFALGDNgtlnLSGEGSNNDYT 244
Cdd:PRK13513  140 IEVVRGPMSSLYGSDAMGGVINIITRKVQKEwhGSLRADATlQEDSKSGDIFQTNAYASGPLIDG----LLGLKVSGLLS 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 245 NRAGDDFrtssIGSttYGQQVFRQGepqthegklqyNAEYSF--NDAAEF-YSFGGYSKRRGETAAFYRPSNASNNIAAI 321
Cdd:PRK13513  216 HRSEDKI----IDG--YNEQRMRNG-----------TATFSLtpDDNNEFdFEIGRYVQDRNSTPGRTLALNGTNSDTQY 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 322 YPNGYLPLINGTLEDTSLvaglrgeladdwhydvsanygkNTYELRTKTINTSLGLNTprsfdNGTLTNDQKQLGFDlsr 401
Cdd:PRK13513  279 DRNNYAITHNGYYDFGNS----------------------TSYIQRDETRNPSRQMKS-----VDTIFNTQTSFLLD--- 328
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 402 efsaawlPHpvSVSFGAEYLHQGYQIEAGQAESyfqtgssglggfrAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRH 481
Cdd:PRK13513  329 -------DH--TLSLGGQYRYEELYDKGNQLPS-------------ASDLNKLTRWSWALFAEDEWQMTNDFALTGGIRM 386
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 482 EDYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQnfTFTSSQLIGntiqeagtfpAGSNVAQLLGAEDLKPE 561
Cdd:PRK13513  387 DQDQNYGTHWTPRLYGVWHLADQWTLKGGVSTGYRSPDLRQA--TDNWGQLTG----------GGGLPALILGNSDLKPE 454
                         570       580       590
                  ....*....|....*....|....*....|...
gi 1189288138 562 KSRNYSLSLVLQPLDSLTVTADVYRIDIQDRIS 594
Cdd:PRK13513  455 KSISQEIGILWDNQENLNASVTLFNTDFKDKIT 487
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
18-757 2.41e-77

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 262.10  E-value: 2.41e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  18 LLSVACISASAHAAQATDEQNSQgASTLSTVIVTGTRaQERTASASLSPIDVISGDSLRSSGSSELGTVLaRLIPSINFP 97
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAED-ATELEEVVVTATR-TEQSLSDAPASVSVITAEEIEKLGATDLADAL-RLLPGVSVT 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  98 RPSLVDGaelTRPAQLRGLSPDQVLVLVlvlvlvNGKRRHTSAFvnlggavgrgSAPADLNAIPLSAIDHIEVLRDGASA 177
Cdd:COG4771    78 RSGGRGG---SSGISIRGLGGDRVLVLI------DGVPVNNPAL----------GGGGDLSYIPPDDIERIEVIRGPASA 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 178 RYGSDAIAGVINIILKSADH--GGSISSKYGQYKKGdgiQRQVSGNTGFAlGDNGTLNLSGEGSNNDYTNRAGDDFRTSS 255
Cdd:COG4771   139 LYGSDAIGGVINIITKKPTDelEGSVSLGYGSNGNG---TYSGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGGFVGN 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 256 IGSTTYgqqvfrqgepqthegKLQYNAEYSFNDAAEFYSFGGYSKRRGEtaafyrpSNASNNIAAIYPNGYLPLINGTLE 335
Cdd:COG4771   215 SGYERY---------------NLNAKLGYRLSDNHRLSLSGGYSRQDRD-------GGPPTLGDTEISSDNAGDRDTTTD 272
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 336 DTSLVAGLRGELADDWhyDVSANYGKNtyelrtkTINTSLGLNTPRSFDNGTLTNDQKQLGFDLSREFSAAWlphpvSVS 415
Cdd:COG4771   273 RGNYSLRYNGDLGDNL--DLSLYYSRT-------DRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNH-----TLT 338
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 416 FGAEYLHQGYQIEagqaesyfqtgssglggfRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFG----SNV 491
Cdd:COG4771   339 LGAEYRYDDLDSS------------------SFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAF 400
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 492 SGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFTFTssqligntiqeagtfpaGSNVAQLLGAEDLKPEKSRNYSLSLV 571
Cdd:COG4771   401 SPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGT-----------------GTPGRYVLGNPDLKPETSDNYELGLE 463
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 572 LQPLD-SLTVTADVYRIDIQDRISLSSNlvlnntainylrsngvgDINYTSARYFTNATDTSTDGVDLVANYRYqfdnGV 650
Cdd:COG4771   464 YRLGNgGLSLSLTGFYTDIKDLIVLVPV-----------------GPGPGDVLQYENVGKARTYGLELELKYRL----GK 522
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 651 RWNSTVGYNYNHTKVTDVKANPAIldqlgvnlvrvdrrerigllgDTTPQHKLTLGNDLTFGNWALHSNLVRYGEFTSYQ 730
Cdd:COG4771   523 GLTLTASYTYLDSKIDDGDTGEPL---------------------PNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVT 581
                         730       740
                  ....*....|....*....|....*...
gi 1189288138 731 A-DKVKDQTFSAAWLLDLAVDYTLKNWV 757
Cdd:COG4771   582 PpSGRLEGYTPGYTLLDLRASYKLTKNL 609
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
66-806 2.25e-66

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 232.73  E-value: 2.25e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  66 PIDVISGDSLRSSGSSELGTVLARlIPSINFPRpslvDGAELTRPAQLRGLSPDQVLVLVlvlvlvNGKRRHTSafvnlg 145
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRR-IPGVSVTR----GGGGGGSTISIRGFGPDRTLVLV------DGLPLASS------ 63
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 146 gavgRGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSADH--GGSISSKYGQYKKGDGIQRQVSGNTG 223
Cdd:cd01347    64 ----NYGRGVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGGGFDVSGA 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 224 FALGDNGTLNLSGegsnndyTNRAGDDFRTSSIGSTTYGQQVfrqgepQTHEGKLQYNaeysFNDAAEFYSFGGYSKRRG 303
Cdd:cd01347   140 LADDGAFGARLYG-------AYRDGDGTIDGDGQADDSDEER------YNVAGKLDWR----PDDDTRLTLDAGYQDQDA 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 304 ETA----AFYRPSNASNNIAAIYPNGYLPLINGTLEDTSLVAGLRGELADDWH-YDVSANYGKNTYELRTKTINTSLGLN 378
Cdd:cd01347   203 DGPggtlPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGWtLRANLSYSYTDNDGDPLILNGGNNAA 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 379 TPRSFDNGTLTN-DQKQLGFDLSREFSAAWLPHPVSVSFGAEYLHQgyqieagqaesyfqtgssglggfraadagSYSRH 457
Cdd:cd01347   283 GGDLGRSGYSSErDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRRE-----------------------------ELDEK 333
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 458 NFAQYLDVETNLTEKLGVSAAVRHEDY--------------SDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQ 523
Cdd:cd01347   334 QTALYAQDTIELTDDLTLTLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGEL 413
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 524 NFTFTSSqligntiqeagtfpagsnVAQLLGAEDLKPEKSRNYSLSLVLQPLDSLTVTADVYRIDIQDRISLSSNLVLNN 603
Cdd:cd01347   414 YGGGSHG------------------GTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLG 475
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 604 TAINYlrsngvgdinytsaryfTNATDTSTDGVDLVANYRyqFDNGVRWnsTVGYNYNHTKVTDVKANPAildqlgvnlv 683
Cdd:cd01347   476 LVTVY-----------------VNGGKARIRGVELEASYD--LTDGLGL--TGSYTYTDTEVKRTDGATT---------- 524
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 684 rvdrreriGLLGDTTPQHKLTLGND--LTFGNWALHSNLVRYGEFTSYQADKVKDQTFSAAWLLDLAVDYTL-KNWVFTL 760
Cdd:cd01347   525 --------GNRLPGIPKHTANLGLDyeLPDEGLTAGGGVRYRGKQYADTANGNNTVKVPGYTLVDLSASYQFtKNLTLRL 596
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*.
gi 1189288138 761 GGDNITDKypeklnDFSSSGGNLAYSTFSPYGYsGAFYYGKVTYNW 806
Cdd:cd01347   597 GVNNLFDK------DYYTSLSVRGSGLYGYYGP-GRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-769 8.67e-48

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 180.41  E-value: 8.67e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  45 LSTVIVTGTRAQERTASASLSpIDVISGDSLRSSGSSELGTVLaRLIPSINFPRPSLVDGAEltrpaQLRGLSpdqvLVL 124
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGS-VSVISREQLEDQPATDLGDLL-RRVPGVSVTSAGGGAGQI-----SIRGFG----GGG 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 125 VLVLVLVNGKRRHTSAFVNlggavgrgsapADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSADHG--GSIS 202
Cdd:COG1629    70 NRVLVLVDGVPLNDPSGGD-----------GGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGkgGEVS 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 203 SKYGQYkkgDGIQRQVSGNTGfalGDNGTLNLSgegsnndYTNRAGDDFRTSSigsttygqqvfrQGEPQTHEGKLQYNa 282
Cdd:COG1629   139 ASYGSY---GTYRASLSLSGG---NGKLAYRLS-------ASYRDSDGYRDNS------------DSDRYNLRAKLGYQ- 192
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 283 eysFNDAAEFYSFGGYSKRRGETAAFyrPSNASNNIAAIYPNGYLPLINGTLEDTSLVAGLRGE---LADDWHYDVSANY 359
Cdd:COG1629   193 ---LGDDTRLTLSASYSDSDQDSPGY--LTLAALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLEyehLGDGLKLSASAYY 267
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 360 GKNTYELRTKTINTSLGLNTPRSFDngtltNDQKQLGFDLSREFSAAWlPHPVSVSFGAEYLHQGYQieagQAESYFQTG 439
Cdd:COG1629   268 RYDDTDLDSDFTPTPADGGTLEQTD-----FDNRTYGLELRLTYDLGF-GGKHTLLVGLDYQRQDLD----GSGYPLDLG 337
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 440 SSGLGGFRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFG----------------SNVSGSLSARYDFTP 503
Cdd:COG1629   338 SGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVddtvtgtdsasgsrsySAFSPSLGLTYQLSP 417
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 504 QVALRGSVSTGFRAPSLAQQNFTFTSSQLIGNTiqeagtfpagsnvaqllgaeDLKPEKSRNYSLSLVLQPLD-SLTVTA 582
Cdd:COG1629   418 NLSLYASYSRGFRAPTFGELYANGTDPYSVGNP--------------------DLKPETSTNYELGLRYRLLDgRLSLSL 477
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 583 DVYRIDIQDRIslssnlvlnntaINYLRSNGVGdinytSARYFTNATDTSTDGVDLVANyrYQFDNGvrWNSTVGYNYNH 662
Cdd:COG1629   478 ALFYSDVDNEI------------LSVPLPNDSG-----FSTYYTNAGKARSYGVELELS--YQLTPG--LSLNASYSYTD 536
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 663 TKVTDVKANPAILDqlGVNLVRVdrrerigllgdttPQHKLTLGNDLTF-GNWALHSNLVRYGEFtsYQADKVKDQTFSA 741
Cdd:COG1629   537 AKFDDDTDGSADLD--GNRLPGV-------------PPLTANLGLTYEFpGGWSLGLGVRYVGDR--YLDDANTQGAPGG 599
                         730       740
                  ....*....|....*....|....*....
gi 1189288138 742 AWLLDLAVDYTL-KNWVFTLGGDNITDKY 769
Cdd:COG1629   600 YTLVDLGAGYRFgDNLTLSLGVDNLFDKK 628
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
18-768 3.56e-35

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 142.76  E-value: 3.56e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  18 LLSVACISASAHAAQAtdeqnsqgASTLSTVIVTGTRAQERTASASLSPIDVISGDSLRSSGSSELGTVLARlIPSINFp 97
Cdd:COG4772     4 ALAAALLLAAAAAAEA--------ATTLETVVVTGSRAAEARLKDVPGSVSVVDREELENQAATSLREVLRR-VPGVNV- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  98 RPSlvDGAELtRPA-QLRGLSPdqvlvlvlvlvlvngkRRhtSAFVNL--GG---AVGRGSAPADLNAIPLSAIDHIEVL 171
Cdd:COG4772    74 QEE--DGFGL-RPNiGIRGLGP----------------RR--SRGITLleDGipiAPAPYGDPAAYYFPDLERMERIEVL 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 172 RDGASARYGSDAIAGVINIILKSA--DHGGSISSKYGQ--YKKGDGIQRQVSGNTGFALgdngtlnlsgegsnnDYTNRA 247
Cdd:COG4772   133 RGAAALRYGPQTVGGAINFVTRTIptAFGGELRVTGGSfgYRRTHASVGGTVGNFGYLV---------------EYSRKR 197
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 248 GDDFRtssigsttygqqvfrqgePQTHEGKLQYNA--EYSFNDAAEFYSFGGYSKRR-----GETAAFYRpSNASNNiaa 320
Cdd:COG4772   198 GDGFR------------------DNSGFDINDFNAklGYRLSDRQELTLKFQYYDEDantpgGLTDAQFD-ADPRQS--- 255
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 321 iypngYLPLINGTLEDTSLVAGLRGELADDWHYDVSANYGKNT------YELRTKTINTSLGLNTPRSFDNgtltndqkq 394
Cdd:COG4772   256 -----YRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSrnwyirQNTADPNTPGLGLRGNPRGYRS--------- 321
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 395 LGFDLSREFSAAWLPHPVSVSFGAEYLHQgyQIEAGQAESYFQTGSSGLGGFRAADagsYSRHNFAQYLDVETNLTEKLG 474
Cdd:COG4772   322 YGIEPRLTHRFELGGVPHTLEVGLRYHRE--EEDRKQYVNTYGQGRSGAGLRRDRR---FSADALAAYAQNRFELTGRLT 396
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 475 VSAAVRHEDYS---------DFGSNVSGS---------LSARYDFTPQVALRGSVSTGFRAPSLAQQNFTFTSSQlignt 536
Cdd:COG4772   397 LTPGLRYEHIRrdrtdrystRTGGDDSGSnsyseflpgLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYGNGGNP----- 471
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 537 iqeagtfpagsnvaqllgaeDLKPEKSRNYSLSLVLQPLDSLTVTADVYRIDIQDRIslssnlvlnntaINYLRSNGVGD 616
Cdd:COG4772   472 --------------------DLKPEKSWNYELGTRGRIGNGLSAEVALFYIDYDNEL------------GSCSAAGGDRS 519
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 617 inytsarYFTNATDTSTDGVDLVANYRYQFDNGVRWNSTVGYNYNHTKVTDvkanpaildqlGVNLVRVDRRerigLLGd 696
Cdd:COG4772   520 -------TFTNAGETRHQGLELALDYDLLKGGGLGLPLFAAYTYTDAEFTS-----------DFGPVFAGNR----LPY- 576
                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1189288138 697 tTPQHKLTLGNDLTFGNWALHSNLVRYGEFTSYQADKVKDQTFSAA---WLLDLAVDYTL-KNWVFTLGGDNITDK 768
Cdd:COG4772   577 -VPRHQLTAGLGYEHGGWTANLNGRYVSEQFTDAANTVADGSFGKIpsyTVLDLSASYDFgKNLSLFAGVNNLFDK 651
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
279-785 1.35e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 126.42  E-value: 1.35e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 279 QYNAEYSFNDAAEFYSFGGYSKRRGETAAFYRPSNASNNIAAIYPNGYLPLINGTLEDTSLVAGLRGELADDWHYDVSAN 358
Cdd:pfam00593   3 QLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 359 YGKNTYELRTKTINTSLGLNTPRSFDNGTLTNDQKQLGFDLSREFSAAWlphpvSVSFGAEYLHQGYQIeagQAESYFQT 438
Cdd:pfam00593  83 LGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSH-----DLLLGVELRTAGLDY---RRLDDDAY 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 439 GSSGLGGFRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFGSN--------------VSGSLSARYDFTPQ 504
Cdd:pfam00593 155 DPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDN 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 505 VALRGSVSTGFRAPSLAQQNFTFTSsqligntiqeagtfpaGSNVAQLLGAEDLKPEKSRNYSLSLVLQPlDSLTVTADV 584
Cdd:pfam00593 235 LSLYASYSRGFRAPSLGELYGSGSG----------------GGGGAVAGGNPDLKPETSDNYELGLKYDD-GRLSLSLAL 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 585 YRIDIQDRISLSSNLVLNNTAINylrsngvgdinytsarYFTNATDTSTDGVDLVANYRyqfdngvRWNSTVGYN-YNHT 663
Cdd:pfam00593 298 FYIDIKNLITSDPDGPGLGGTVY----------------TYTNVGKARIRGVELELSGR-------LWGLGLSGGgYTYT 354
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 664 KVTDVKANPAILDQLgvnlvrvdrrerigllgDTTPQHKLTLGNDLTF--GNWALHSNLVRYGEFTSYQADKVKDQTFSA 741
Cdd:pfam00593 355 DADDDADADDTGNPL-----------------PNVPRHTANLGLTYDFplGGWGARLGARYVGSGERRYGDAANTFKTPG 417
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 1189288138 742 AWLLDLAVDYTL-KNWVFTLGGDNITDKYPEKLNDFSSSGGNLAY 785
Cdd:pfam00593 418 YTLVDLSAGYRLnKNLTLRLGVNNLFDKYYKRYYSSGGGNLGGYP 462
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
149-785 2.14e-24

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 109.04  E-value: 2.14e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 149 GRGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSAD---HGGSisSKYGQYKKG-DGIQRQVSGNTGF 224
Cdd:TIGR01786  89 GQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAAdllKPGK--DLGGLSKLGySSANNRFTQSVAA 166
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 225 AL-GDN------GTLNLSGEGSNNDYTNrAGDDFRTSSIGSTTYGQQVFRqgepqtheGKLQYnaeySFNDAAEFYSFGG 297
Cdd:TIGR01786 167 AGrNDDvdalvqATYRRGHELKNGNKAN-IGNESKRSKPNPSDYKSQSFL--------AKLGW----QLNDAHRLGLSLE 233
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 298 YSKRRGETAAFYRPSNASNNIAAIYPNGYLPLINGT--LEDTSLVAGLRGElaDDWHYDVSANYGKNTYELRTKTINTSL 375
Cdd:TIGR01786 234 YTQTDYDEPEMTNTSYLTKPLGAPLLSSTVVLGDSKtrDRRTGLDYELNPD--NSWLDTVKLALDKQYIQLYNYLNATSA 311
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 376 GlnTPRSFDNGTLTNDQKQ---LGFDLsrEFSAAWLPHPVSVSFGAEYLHQGYQIEAGQAEsyFQTGSSGLGGFRAaDAG 452
Cdd:TIGR01786 312 S--DYPGVDKNGRYKDKYDyytLGFDT--NNKIEFSVHSLSLTYGLDRFKDKVSTGDSRRN--LPTAAYNLYGYEG-ENR 384
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 453 SYSRHNFAQYLDVETNLTEKLGVSAAVR--------------HEDYSDFGSNV-SGSLSARYDFTPQVALRGSVSTGFRA 517
Cdd:TIGR01786 385 PVKGSNFGLFLQDNIKLGDWLSLSAGLRydhyktdpkadeskDYGAISKTYSRwSPSLGLTYKPTPWLTLYYSYSQGFRA 464
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 518 PSLAQQNFTFTssqligntiqeagtfPAGSNVAQLLGAEDLKPEKSRNYSLSLVLQpLDSLTVTADVYRIDIQDRISLSS 597
Cdd:TIGR01786 465 PSFDELYGTGA---------------HPGGGPYTFLPNPNLKPETSKNWEIGINLH-FDQLDFKVSYFRNDYKDFIDLGI 528
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 598 nlvLNNTAINYlrsNGVGDINYTSaryFTNATDTSTDGVDLVANYRYQFDNGVRWNSTVGYNYNHTKVTDVKANPAildq 677
Cdd:TIGR01786 529 ---GVTAKGNM---AQVGSNTITN---YVNIDNARIRGIELSGRYDLGSFFSGPDGWTTTLKYGYTKGKDSDTNPW---- 595
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 678 lgvnLVRVDRRERIGLLGDTTPQHKLTLGNDLTFgnWALHSNLVRYGEFTSYQADKVKDQTFSAAW-LLDLAVDYTL-KN 755
Cdd:TIGR01786 596 ----LNAITPLKVVLGLGYDHPDEKWGVGLTLTF--SGAKDAVDAYATYYENGEAAKAGPLRTPSYtVVDLYGYYKPnKN 669
                         650       660       670
                  ....*....|....*....|....*....|.
gi 1189288138 756 WVFTLGGDNITD-KYPEKLNDFSSSGGNLAY 785
Cdd:TIGR01786 670 LTLRFGVYNLLDrKYTTWESARQAGPLATGY 700
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
158-768 9.31e-24

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 106.89  E-value: 9.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 158 NAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSA--DHGGSISSKYGQYKkgdgiQRQVSGNTGFALGDNGTLNLS 235
Cdd:COG4774    74 YRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPtdEPFTEVTLTYGSDG-----QRRATLDVNGPLGDDLAYRLN 148
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 236 GEGSNNDyTNRAGDDFRTSSI-GSTTYGqqvfrqgepqthegklqynaeysFNDAAEFYSFGGYSKRRGeTAAFYRPSNA 314
Cdd:COG4774   149 GMYRDSD-SYRDGVDNDRWGIaPSLTWR-----------------------LGDRTRLTLDYEYQDDDR-TPDYGVPAVA 203
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 315 SNNIAAIYPNGYLPLINGTLEDTSLVAGLRGE--LADDWHYDVSANYGKNTYELRTKTINTSLGLNT-PRSFDNGTLTND 391
Cdd:COG4774   204 NGRPVDVDRSTFYGQPDDYSDSETDSATLRLEhdFNDNWTLRNALRYSDYDRDYRNTYPTGGNATGTvTRSAYRRDQDND 283
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 392 QKQLGFDLSREFSAAWLPHpvSVSFGAEYLHQGYQIEAGQAESYFQTGS-------SGLGGFRAADAGSYSR-HNFAQYL 463
Cdd:COG4774   284 TLSNQTDLTGKFDTGGVKH--TLLAGVEYSREDSDNARYSGGGTAPTVNlynpvygAPVTGPTLGGADNDSRtDTTGLYL 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 464 DVETNLTEKLGVSAAVRHE----DYSDFGSN----------VSGSLSARYDFTPQVALRGSVSTGFRapslaqqnftfts 529
Cdd:COG4774   362 QDTISLTDRWSLLAGLRYDrfdtDYTDRTTGattssyddsaFSPRAGLVYKPTPNLSLYASYSTSFN------------- 428
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 530 sqligntiqeagtfPAGSNVAQLLGAEDLKPEKSRNYSLSLVLQPLD-SLTVTADVYRIDIQdrislssNLVLNNTainy 608
Cdd:COG4774   429 --------------PGGGAPSLSNAGQALDPEKSRQYEVGVKWDLLDgRLSLTAALFRIEKT-------NVRTTDP---- 483
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 609 lrsngvgdinyTSARYFTNATDTSTDGVDLVANYRYqfdnGVRWNSTVGYNYNHTKVTDvkanpaildqlGVNLVRVDRR 688
Cdd:COG4774   484 -----------ANPGVYVQTGEQRSRGVELEATGEL----TPGWSVLAGYTYLDAEITK-----------SANAANVGNR 537
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 689 erigLLGdtTPQHKLTLGN--DLTFGNWALHSNLVRYGEFTSYQADKVKdqtFSAAWLLDLAVDYTL-KNWVFTLGGDNI 765
Cdd:COG4774   538 ----LPN--VPRHSASLWTtyDLPLPGLTLGGGVRYVGSRYADAANTVK---LPSYTRFDAGASYRLnKNLTLRLNVNNL 608

                  ...
gi 1189288138 766 TDK 768
Cdd:COG4774   609 TDK 611
PRK13513 PRK13513
ligand-gated channel protein;
15-594 1.10e-23

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 106.78  E-value: 1.10e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  15 SANLLSVACISASAHAAQATDEqnsqgASTLSTVIVTGTRAQERTASASLSpIDVISGDSLRSSGSSELGTVLaRLIPSI 94
Cdd:PRK13513   10 KAALVIAAAISSQAYAAEKTNT-----ATPTDTMVVTASGFQQRIQDAPAS-ISVVTREQLENKAYRDVTDAL-KDVPGV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  95 nfprpsLVDGAELTRPAQLRGLSPdqvlvlVLVLVLVNGKRRHTsafvnlggavgRGSAP-ADLNAI------PLSAIDH 167
Cdd:PRK13513   83 ------VVTGGGSTSDISIRGMAA------KYTLILVDGKRVDT-----------RSTRPnSDGSGIeqgwlpPLAAIER 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 168 IEVLRDGASARYGSDAIAGVINIILKSADHG--GSISSKYG-QYKKGDGIQRQVSGNTGFALGDNgtlnLSGEGSNNDYT 244
Cdd:PRK13513  140 IEVVRGPMSSLYGSDAMGGVINIITRKVQKEwhGSLRADATlQEDSKSGDIFQTNAYASGPLIDG----LLGLKVSGLLS 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 245 NRAGDDFrtssIGSttYGQQVFRQGepqthegklqyNAEYSF--NDAAEF-YSFGGYSKRRGETAAFYRPSNASNNIAAI 321
Cdd:PRK13513  216 HRSEDKI----IDG--YNEQRMRNG-----------TATFSLtpDDNNEFdFEIGRYVQDRNSTPGRTLALNGTNSDTQY 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 322 YPNGYLPLINGTLEDTSLvaglrgeladdwhydvsanygkNTYELRTKTINTSLGLNTprsfdNGTLTNDQKQLGFDlsr 401
Cdd:PRK13513  279 DRNNYAITHNGYYDFGNS----------------------TSYIQRDETRNPSRQMKS-----VDTIFNTQTSFLLD--- 328
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 402 efsaawlPHpvSVSFGAEYLHQGYQIEAGQAESyfqtgssglggfrAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRH 481
Cdd:PRK13513  329 -------DH--TLSLGGQYRYEELYDKGNQLPS-------------ASDLNKLTRWSWALFAEDEWQMTNDFALTGGIRM 386
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 482 EDYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQnfTFTSSQLIGntiqeagtfpAGSNVAQLLGAEDLKPE 561
Cdd:PRK13513  387 DQDQNYGTHWTPRLYGVWHLADQWTLKGGVSTGYRSPDLRQA--TDNWGQLTG----------GGGLPALILGNSDLKPE 454
                         570       580       590
                  ....*....|....*....|....*....|...
gi 1189288138 562 KSRNYSLSLVLQPLDSLTVTADVYRIDIQDRIS 594
Cdd:PRK13513  455 KSISQEIGILWDNQENLNASVTLFNTDFKDKIT 487
PRK13483 PRK13483
ligand-gated channel protein;
11-594 2.06e-23

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 106.01  E-value: 2.06e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  11 TAIFSANLLSVACISASAHAAQAtdEQNSQGASTLSTVIVT--GTRAQERTASASLSpidVISGDSLRSSGSSELGTVLa 88
Cdd:PRK13483    1 MKKYLAQVISALCLLPAVFVTHA--LAQAAPDKTMETVVVTasGYEQQIRDAPASIS---VITREDLENRFYRDLTDAL- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  89 RLIPSINfprpslVDGAELTRPAQLRGLSPDqvlvlvLVLVLVNGKR---RHTSAFVNlGGAVGRGSAPadlnaiPLSAI 165
Cdd:PRK13483   75 LDVPGVV------VTGGGDRTDISLRGMGSQ------YTLILVDGKRqssRETRPNSD-GPGVEQAWTP------PLAAI 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 166 DHIEVLRDGASARYGSDAIAGVINIIL-KSADHGgsisskYGQYKKGDGIQ-RQVSGN--------TGFALGDNGTLNLS 235
Cdd:PRK13483  136 ERIEVIRGPMSSLYGSDAIGGVINIITrKVPNEW------QGEVRLDTTLQeNSDSGNvyqanffvNGPLIKDLLGLQLY 209
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 236 GEgsnndYTNRAGDD----FRTSSIGSTT--YGQQVFRQGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGEtaafy 309
Cdd:PRK13483  210 GQ-----YTQREEDDieggYRDKDARSLTakLALTPNEDHDIMLEVGTSNQERDSTVGKTVAPLAPGESCGRRGC----- 279
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 310 rPSNASNNiaaiYPNGYLPLI-NGtledtslvaglrgeladDWHYDVSanygkNTYELRTKTINTSLGLntprSFDNgtl 388
Cdd:PRK13483  280 -PESSTTE----YERSTVSLShTG-----------------RWDFGTS-----DTYIQHEEFDNKSREM----KIKN--- 325
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 389 TNDQKQLGFDLSREfsaawlpHpvSVSFGAEYLHQGYQIEAGQaesyfqtgssglggfRAADAGSYSRHNFAQYLDVETN 468
Cdd:PRK13483  326 TDFQSSLVAPLGQE-------H--TLTFGAAYNHQDLTDETSN---------------QISDLTDISRTQWAVFSEDEWR 381
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 469 LTEKLGVSAAVRHEDYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQqnftftssqlignTIQEAGTFPAGSN 548
Cdd:PRK13483  382 IADDFALTGGLRLDHDENFGGHVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQ-------------TTPDWGQVSRGGN 448
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 1189288138 549 VaqlLGAEDLKPEKSRNYSLSLVLQPLDSLTVTADVYRIDIQDRIS 594
Cdd:PRK13483  449 I---YGNPDLKPETSLNKELGLYYDLGSGLTASLTVFYNEFKDKIT 491
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
18-769 2.31e-23

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 105.75  E-value: 2.31e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  18 LLSVACISA-SAHAAQATDEQNSQGASTLSTVIVTGTRAQE------RTASASLSP---------IDVISGDSLRSSGSS 81
Cdd:COG4773     4 LLAGSGLAAaAAGALAQAAAAAAAEATTLPEVTVTGTAEGTggytakSSSTATKLDtplretpqsVSVVTRQLIEDQGAT 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  82 ELGTVLaRLIPSINfprPSLVDGAELTRPaQLRGLSPDqvlvlvlvlvlvngkrrhtSAFVNlggavGRGSAPADLNAIP 161
Cdd:COG4773    84 TLDDAL-RNVPGVT---VSSYDGGGRDSF-SIRGFSID-------------------NYLRD-----GLPLGGFGGGQPD 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 162 LSAIDHIEVLRDGASARYGSDAIAGVINIILK--SADHGGSISSKYGQYKkgdgiQRQVSGNTGFALGDNGT----LNLS 235
Cdd:COG4773   135 TANLERVEVLKGPAGLLYGAGSPGGLVNLVTKrpTAEPQGEVSLSAGSWD-----TYRATADVGGPLNEDGTlryrLNAA 209
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 236 GEGSNNdYTNRAGDDfRTSSIGSTTYgqqvfrQGEPQThegKLQYNAEYSFNDAAEFYSFGGYSKRRGETAAFYRPSNAS 315
Cdd:COG4773   210 YEDGDS-FRDGVDNR-RTLIAPSLDW------DLTDDT---TLTLGAEYQDDDSTGDRGFLPLDGTLLDLPRSTNLGEPW 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 316 NNIaaiypngylplingTLEDTSLVAGLRGELADDWHYDVSANYGKNTYELRTKTINTSLGLNT---PRSFDNGTLTNDQ 392
Cdd:COG4773   279 DYY--------------DTETTTLFAELEHRFNDDWSLRANARYSDSDRDGRSAYAYGAPDAATgtlTRYASARDGDSRS 344
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 393 KQLGFDLSREFSAAWLPHpvSVSFGAEYLHQGYQIEAGQAESY----FQTGSSGLGGFRAADAGSYSRhNFAQYLDVETN 468
Cdd:COG4773   345 DSLDANLNGKFETGGLEH--TLLVGADYSRYDSDSDSATAGTIniynPVYGNLPEPDFDASDTDTTTR-QTGLYAQDQIS 421
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 469 LTEKLGVSAAVRHEDYSDFGSNVSGSLSAR-------------YDFTPQVALRGSVSTGFRAPSlaqqnftftssqlign 535
Cdd:COG4773   422 LTDRLSLLLGGRYDWYETDSTNRLGGSTTSyddsaftpraglvYDLTPGLSLYASYSESFEPQS---------------- 485
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 536 tiqeaGTFPAGsnvaqllgaEDLKPEKSRNYSLSLVLQPLDS-LTVTADVYRIDIQDRislssnLVLNNTAINYLRSNGv 614
Cdd:COG4773   486 -----GADNNG---------NPLDPETGKQYEAGVKGELFDGrLNATLAVFDITQKNV------ATTDPDNPNFYVQVG- 544
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 615 gdinytsaryftnatDTSTDGVDLVANYRYqFDNgvrWNSTVGYNYNHTKVTDvkanpaildqlgvnlvrvDRRERIGLL 694
Cdd:COG4773   545 ---------------EVRSRGVELELSGEL-TPG---LNLIAGYTYTDAKITK------------------DADALEGKR 587
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 695 GDTTPQHKLTLGNDLTFGNWALhSNL-----VRYgeFTSYQADKVKDQTFSAAWLLDLAVDYTL-KNWVFTLGGDNITDK 768
Cdd:COG4773   588 LTNVPRHTASLWTTYRFPSGAL-KGLglgggVRY--VGERYGDAANTFTLPSYTLVDAGARYDLgKNWTLQLNVNNLFDK 664

                  .
gi 1189288138 769 Y 769
Cdd:COG4773   665 K 665
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
13-664 2.34e-22

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 102.66  E-value: 2.34e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  13 IFSANLLSVACISASAHAAQATDEQNSQGASTLsTVIVTGTRAQERTASASLSpidVISGDSLRSSGSSELGTVLaRLIP 92
Cdd:PRK10064    1 MFRLNPFVRVGLCASAISCAWPVLAVDDDGETM-VVTASAVEQNLKDAPASIS---VITQEDLQRKPVQNLKDVL-KEVP 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  93 SInfprpSLVDGAELTRPAQLRGLSpdqvlvLVLVLVLVNGKRrhtsafVNLGGAVGRGSaPADLNAIPLSAIDHIEVLR 172
Cdd:PRK10064   76 GV-----QLTNEGDNRKGVSIRGLD------SSYTLILIDGKR------VNSRNAVFRHN-DFDLNWIPVDAIERIEVVR 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 173 DGASARYGSDAIAGVINIILKSAD---HGGSISSKYGQYKKGDGIQRQVSGNTGFALGDnGTLNLSGEGSnndYTNRAGD 249
Cdd:PRK10064  138 GPMSSLYGSDALGGVVNIITKKIGqkwHGTVTVDTTIQEHRDRGDTYNGQFFTSGPLID-GVLGMKAYGS---LAKREKD 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 250 DFRTSSIGSTtygqqvfrqGEPQTHEG--KLQYNAEYSF--NDAAEFYSFGGYSKRRGETAAFYRPSNASNNIAAIYpNG 325
Cdd:PRK10064  214 DPQNSTTTDT---------GETPRIEGftSRDGNVEFAWtpNQNHDFTAGYGFDRQDRDSDSLDKNRLERQNYSLSH-NG 283
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 326 YLPLINGTLEdtslvagLRGELADDwhydvsaNYGKNTYELRTKTINTSLGLNTPRSFDNGTLTndqkqlgfdlsrefsa 405
Cdd:PRK10064  284 RWDYGNSELK-------YYGEKVEN-------KNPGNSSPITSESNSIDGKYTLPLTAINQFLT---------------- 333
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 406 awlphpvsvsFGAEYLHQGYQieagqaESYFQTGssglGGFRAADAGSYsrhnfAQYLDVETNLTEKLGVSAAVRHEDYS 485
Cdd:PRK10064  334 ----------FGGEWRHDKLS------DAVNLTG----GTSSKTSASQY-----ALFVEDEWRIFEPLALTTGVRMDDHE 388
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 486 DFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFTFTSSQLIGNtiqeagtfpagsnvAQLLGAEDLKPEKSRN 565
Cdd:PRK10064  389 TYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGA--------------CKIVGSPDLKPETSES 454
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 566 YSLSLVLQP----LDSLTVTADVYRIDIQDRISLS--SNLVLNNTAINYLRSNGVGDINYTSARYFTNATDTSTDGVDlv 639
Cdd:PRK10064  455 WELGLYYMGeegwLEGVESSVTVFRNDVDDRISISrtSDVNAAPGYQNFVGFETNGRGRRVPVFRYYNVNKARIQGVE-- 532
                         650       660
                  ....*....|....*....|....*
gi 1189288138 640 ANYRYQFDNGvrWNSTVGYNYNHTK 664
Cdd:PRK10064  533 TELKIPFNDE--WKLSLNYTYNDGR 555
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
45-742 9.91e-22

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 100.54  E-value: 9.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  45 LSTVIVTGTRaQERTASASLSPIDVISGDSLRSSGSSELGTVLARlIPSINFPRPSLVDGAELTrpaqLRGLSPDQVLVL 124
Cdd:TIGR01785   1 LDTVTVTATR-TRQVLSEAPASVSVISGEQIESKQANNLADALNT-VPGVDVTGGGRPPGQSIN----IRGLQDNRVLVV 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 125 VlvlvlvNGKRrhtSAFVNLGGAVGRgsapadlNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSA--------D 196
Cdd:TIGR01785  75 V------DGAR---QNYQRGGAHNGS-------LFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAadllrpgqL 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 197 HGGSISSKYGqykkGDGIQRQVSGNTGFALGDNGTLNLSgegsnndYTNRAGDDFRTSS---IGSTTYGQQVF----RQG 269
Cdd:TIGR01785 139 FGGLAKLSYG----SNNNSFGGSVAVAGRLDDNLDALVA-------ATYRDGGNYRNGNkeeATNSAYVQKNLlaklGWQ 207
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 270 EPQTHEGKLQY-NAEYSFNDAAEfySFGGYSKRRGETAAFYRPSNASNNIAAIYpnGYLPLINGTLEDTSLVAGLRGELa 348
Cdd:TIGR01785 208 LDDAQRLEFSYfTTEGSLDEAQN--SGPGTEYVLGSSSTLLASSTRDRSATLTY--NWTPEDNPWLDATASLYYNRTEN- 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 349 ddWHYDVSANYG-KNTYELRTKTIN----TSLGLNTPRSFDNGTLTNDQKQLGFDLSREFSAAWLPHPVSvsfGAEYLHQ 423
Cdd:TIGR01785 283 --DNDRSARGVGrEEGYQYTTYGATlqntSRFDVASWSTLTYGVDWMKDKRRTESFDPNSVTTIVPNPPS---AKEYFFG 357
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 424 GYqieaGQAESYFqtgssglggfraadagsysrhnfaqyldvetnLTEKLGVSAAVRH------------EDYSDFGSNV 491
Cdd:TIGR01785 358 LF----LQDNIPL--------------------------------LDDRLTLSAGLRYdhyklspkttadTEAVDRSYSR 401
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 492 -SGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFTftssqligntiqeaGTFPAGSNVAQLLGAEDLKPEKSRNY---- 566
Cdd:TIGR01785 402 wSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYGT--------------GDHPGTPGGYTFAPNPNLKPETSKTWelga 467
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 567 --SLSLVLQPLDSLTVTADVYRIDIQDRISLSSNLVLNNTAINYLRSNgvgdinytsaryFTNATDTSTDGVDLVANYRY 644
Cdd:TIGR01785 468 nlSFDNLLLDNDQLQFKVAYFYNDVKDFIDLTIGVTDNVTAGMNNITQ------------YVNIDGARIRGIEASASYDA 535
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 645 QfdngvRWNstVGYNYNHTKVTDVKANPAiLDQ-------LGVNLVRVDRRERIGLLGD-TTPQHKLTLGNDLTFGNWAL 716
Cdd:TIGR01785 536 G-----LWA--TGLSYGYTIGKDQNTNQW-LSNipplklvVTVGYRFPDRRLDLGAKAAyYERQSESPTTEDVAANGLLT 607
                         730       740
                  ....*....|....*....|....*.
gi 1189288138 717 HSNLVRYGEFTSYQADKVKDQTFSAA 742
Cdd:TIGR01785 608 TPGYTVVDLYATYQPNAVKGLTVRFG 633
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
150-769 1.65e-19

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 93.25  E-value: 1.65e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 150 RGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKsadHGGSISSKYGQYKKGDGIQRQVSGNTGFALGDN 229
Cdd:TIGR01783  66 PLLSRGNLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTK---RPQDEPKGSVTFGAGTRSGYRTAFDLGGPLGAD 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 230 GTLNLSGEGSNNDYTN-RAGDDFRTSSIGSTTYGQQvfrqgEPQThegKLQYNAEYSfNDAAEFYSfGGYSKRRGEtaaf 308
Cdd:TIGR01783 143 GTFRGRLNGARQDGDSfYDGAGEETRLGATATDWQL-----DDRT---LLRLGAYYQ-KERDRGGY-GGLPASGGT---- 208
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 309 YRPSNASNNIAAIYPNGYLPlingTLEDTSLVAGLRGELADDWHYDVSANYGKNT----YELRTKTINTSLGLNtpRSFD 384
Cdd:TIGR01783 209 SGRDLSSDRYLGTSSNRNYD----DREYLSYGLSLEYQFNDVWTGKQNLRYSYFDtdsnQVQASGYSSDGGLFG--RSLT 282
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 385 NGTLTNDQKQLGFDLSREFSAAwlPHPVSVSFGAEYLHQGYQIEAGQAESYFQTGSSGLGGFRAADAGSY------SRHN 458
Cdd:TIGR01783 283 VVNVKQDRVQIDAGLDGEFETG--PIEHDLLLGVSYGQRTTNRFNNTGYPSDNIYSLTATSSARTDIGDSpkdralSSTT 360
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 459 FAQ---YLDVETnLTEKLGVSAAVRHE-------------DYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQ 522
Cdd:TIGR01783 361 KALngvALQRIL-LADKWTLTLGGRYDsvdvksnngvagsTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYP 439
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 523 QnftftssqligntiqeagtfpagsnvAQLLGAEDLKPEKSRNYSLSLVLQPLDSLTVTADVYRIDIQdrislssnlvln 602
Cdd:TIGR01783 440 K--------------------------GAGNSGDILEPEKGKNYELGVRYDLGDSLLATAALFRITKD------------ 481
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 603 ntaiNYLRSNGVGDINYtsaryfTNATDTSTDGVDLVANYRYQFDngvrWNSTVGYNYNHTKVTDVKANPAILDQLGvnl 682
Cdd:TIGR01783 482 ----NQLVQDPVNGTFS------VNAGKTRNRGVELEARGYLTPG----LSLSAGYTYTDAEFTEDTNGDTQGNTVP--- 544
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 683 vrvdrrerigllgdTTPQHKLTLGNDLTFGNWALHSNLVRYGEFT-SYQADKVKDQTFSAAWLLDLAVDYTL---KNWVF 758
Cdd:TIGR01783 545 --------------FVPKHTASLWASYAPPVGDNGLTLGGGVQYTgKAYVDGGNTGKVPSYTVVDLSVRYDLtkkKNLTL 610
                         650
                  ....*....|.
gi 1189288138 759 TLGGDNITDKY 769
Cdd:TIGR01783 611 ALNVNNLFDRD 621
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
18-570 1.71e-19

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 93.56  E-value: 1.71e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  18 LLSVACISASAHAAQATDEQNSQGASTLSTVIVTGTRaQERTASAslspIDVISGDSLRSSGSSELGTVLARLIPSINFP 97
Cdd:PRK13524   11 LVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTAAE-QNLQAPG----VSTITAEDIRKRPPANDVSEIIRTMPGVNLT 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  98 RPSLVDGAELTRPAQLRGLSPDQVLVLVlvlvlvNGKRRHTSAFVNLGGAVGRGSApADLNAIPLSAIDHIEVLRDGASA 177
Cdd:PRK13524   86 GNSTSGQRGNNRQIDIRGMGPENTLILI------DGKPVSSRNSVRYGWRGERDTR-GDTNWVPPEMIERIEVLRGPAAA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 178 RYGSDAIAGVINIILKSAD---HgGSISSKYGQYK-KGDGIQRQVSGNTGFALGDNGTLNLSGEGSNND----YTNRAGD 249
Cdd:PRK13524  159 RYGNGAAGGVVNIITKKPTgewH-GSWNTYFNAPEhKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQadawDINQGHQ 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 250 DFRTSSIGSTTYGQqvfRQG-EPQTHEGKLQYnaEYSFNDAAEFYsfGGYSkRRGETAAFYRPSNASNNIAA-------- 320
Cdd:PRK13524  238 SARTGSYAGTLPAG---REGvINKDINGLLRW--DFAPLQSLELE--AGYS-RQGNLYAGDTQNTNSDALVKslygketn 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 321 -IYPNGYLPLINGtledtslvaglrgeladDWHYDVSanygKNTYELRTKTINTSL--GL---------NTPRSFDNGTL 388
Cdd:PRK13524  310 rMYRQNYALTHRG-----------------GWDNGVS----TSNYAQYEHTRNSRLpeGLaggtegifnEKATQFSTIDL 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 389 TNdqkqlgFDLSREFS---AAWLPHpvSVSFGAEYLHQgyQIEAGQAESYFQTGSSGLGGFRAADAGSYSR-HNFAQYld 464
Cdd:PRK13524  369 DD------VMLHSEVNlpfDLLVNQ--TLTLGTEWNQQ--RMKDPSSNTQALTSGGAIPGVSATGRSPYSKaEIFSLF-- 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 465 VETN--LTEKLGVSAAVRHEDYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQN---FTFTSSQligntiqe 539
Cdd:PRK13524  437 AEDNmeLTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQTNpnyILYSKGQ-------- 508
                         570       580       590
                  ....*....|....*....|....*....|.
gi 1189288138 540 aGTFPAGSNVAQLLGAEDLKPEKSRNYSLSL 570
Cdd:PRK13524  509 -GCYASAGNGCYLQGNDDLKAETSVNKEIGL 538
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
48-326 1.06e-18

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 87.23  E-value: 1.06e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  48 VIVTGTRAqERTASASLSPIDVISGDSLRSSGSSELGTVLARLiPSINFPRPSLVDGAelTRPaQLRGLSPDQVLVLVlv 127
Cdd:COG4206     1 VVVTATRL-EQSKSDLTGSVTVIDAEELERSGATSLADALRRV-PGVQVSSSGGPGSA--ASI-SIRGLGSNQTLVLI-- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 128 lvlvNGkrrhtsafVNLGGAVGRGsapADLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSADHG--GSISSKY 205
Cdd:COG4206    74 ----DG--------VPLNDPSLGG---VDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGfkGSVSASY 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 206 GQY--KKGDGIQRQVSGNTGFALG------DNGTLNLSGEGSNNDYTN---------RAGDDFRTSSIGSTTYGQQVFRQ 268
Cdd:COG4206   139 GSFgtRRLSASLSGGAGKFSYSLSasyrrsDGYRYNDPDLRNNDGYENtslnarlgyKLGDNGSLSLSGGYSDSERGYPG 218
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1189288138 269 GEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETAAFYRPSNASNNIAAIYPNGY 326
Cdd:COG4206   219 AVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
19-599 2.71e-18

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 89.28  E-value: 2.71e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  19 LSVACISASAHAAQAtdeqnsqgastlSTVIVTGTRAQErTASASLSPIDVISGDSLRSSGSSELGTVLARLiPSIN--- 95
Cdd:PRK10641   11 LSVTAFSGWAQDTSP------------DTLVVTANRFQQ-PVSTVLAPTTVVTRDDIDRWQSKSVNDVLRRL-PGVDiaq 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  96 ----------FPRPS-------LVDGAELTRPaqlrGLSpdqvlvlvlvlvlvngkrrhtsafvnlggavgrGSApaDLN 158
Cdd:PRK10641   77 ngglgqlsslFIRGTnsshvlvLIDGVRLNQA----GIS---------------------------------GSA--DLS 117
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 159 AIPLSAIDHIEVLRDGASARYGSDAIAGVINIILKSADHGGSISSKYGQ--YKKGDGIQRQvsgntgfALGDNGTLNLSG 236
Cdd:PRK10641  118 QIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTLSAGWGSngYQNYDGSTQQ-------QLGDNTRVTLAG 190
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 237 egsnnDYTNRAGddFRTSSIGSTTYGQQVFRQGepqtHEGKLQY-NAEYSFNDAAEFYSFG-GYSKRrgeTA--AFYRPS 312
Cdd:PRK10641  191 -----DYTYTKG--FDVVAYGNTGTQAQPDRDG----FMSKTLWgGLEHQFNDQWSGFVRGyGYDNR---TDydAYYSPG 256
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 313 NASNNIAAIYPNGYlplingtleDTslvaGLRGElADDWHYDVSANYGkntyelRTKTINTSlglNTPRSFDNGTLTNDQ 392
Cdd:PRK10641  257 SPLIDTRQLYSQSW---------DA----GLRYN-GGIYSSQLIASYS------HSKDYNYD---PHYGRYDSSATLDDM 313
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 393 KQlgfdlsreFSAAW-----LPHPvSVSFGAEYLHQgyQIEAGQaesyfQTGSSGlggfraadagsYSRHNFAQYLDVEt 467
Cdd:PRK10641  314 KQ--------YNVQWgntvqVGHG-NISAGVDWQKQ--TTTPGT-----GYVPDG-----------YDQRNTGIYLTGQ- 365
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 468 nltEKLG---VSAAVRHEDYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQnftftssqligntiqeagtFP 544
Cdd:PRK10641  366 ---QQIGdvtLEGAARSDDNSQFGWHGTWQTSAGWEFIDGYRFIASYGTAFKAPNLGQL-------------------YG 423
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1189288138 545 AGSNvaqllgaEDLKPEKSRNYSLSL--VLQPLDsLTVTAdvYRIDIQDRISLSSNL 599
Cdd:PRK10641  424 FYGN-------PNLKPEESKQWEGGFegLTGPVN-WRLSG--YRNDIDNLIDYDDHT 470
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
156-593 6.85e-18

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 88.27  E-value: 6.85e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 156 DLNAIPLSAIDHIEVLRDGASARYGSDAIAGVINIILK--SADHGGSISSKYGQYKKGD-GIQRQVSGN-TGFALGDNGT 231
Cdd:PRK13528  135 DTNWVPPEMVERIEVIRGPAAARYGSGAAGGVVNIITKrpTNDWHGSLSLYTNQPESSKeGATRRANFSlSGPLAGDALT 214
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 232 LNLSGegsNNDYTNRAGDDFRTSSIGSTTYG-------------------QQVF-------RQGepQTHEGKLQYNAEYS 285
Cdd:PRK13528  215 MRLYG---NLNKTDADSWDINSSAGTKNAAGregvrnkdingvlswkmtpQQILdfeagysRQG--NIYAGDTQNSNSSA 289
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 286 FNDaaefysfgGYSKRRGETAAFYRPSnasnniAAIYPNG-----------YLPLINGTLEDTSLVAGLRGELADDWHYD 354
Cdd:PRK13528  290 VTE--------SLAKSGKETNRLYRQN------YGLTHNGiwdwgqsrlgfYYEKTNNTRMNEGLAGGGEGRITADQTFT 355
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 355 VSanygkntyelRTKTINTSLGLNTPrsFDngtltndqkqLGFDLSrefsaawlphpvsVSFGAEYLHQgyqiEAGQAES 434
Cdd:PRK13528  356 TS----------RLESYRTSGELNVP--LN----------WLFEQT-------------LTVGAEWNRD----ELNDPSS 396
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 435 YFQTGSSGLGGFRAADAGSYSRHNFAQ----YLDVETNLTEKLGVSAAVRHEDYSDFGSNVSGSLSARYDFTPQVALRGS 510
Cdd:PRK13528  397 TSLTVKDGDIGGISGSAADRSSKNKSEisalYVEDNIEPVPGTNLIPGLRFDYHSEFGSNWSPSLNLSQELGDYFKVKAG 476
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 511 VSTGFRAPSLAQQN---FTFTSSQLIGNTIQEAGTFpagsnvaqLLGAEDLKPEKSRNYSLSLVLQPlDSLTVTADVYRI 587
Cdd:PRK13528  477 IARAFKAPNLYQSSegyLLYSRGNGCPKDITSGGCY--------LVGNKNLDPEISVNKEIGLEFTV-DDYHASVTYFRN 547

                  ....*.
gi 1189288138 588 DIQDRI 593
Cdd:PRK13528  548 DYQNKI 553
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
22-594 1.21e-15

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 81.21  E-value: 1.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  22 ACISASAHAAQATDEQnsqgasTLsTVIVTGTRAQERTASASLSpidVISGDSLRSSGSSELGTVLaRLIPSINfprpsl 101
Cdd:PRK13484   16 SAVISSGYASSDKKED------TL-VVTASGFTQQLRNAPASVS---VITSEQLQKKPVSDLVDAV-KDVEGIS------ 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 102 VDGAELTRPAQLRGLSPDqvlvlvLVLVLVNGKRRHT-SAFVNLGGAVGRGSAPadlnaiPLSAIDHIEVLRDGASARYG 180
Cdd:PRK13484   79 ITGGNEKPDISIRGLSGD------YTLILVDGRRQSGrESRPNGSGGFEAGFIP------PVEAIERIEVIRGPMSSLYG 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 181 SDAIAGVINIILKSADHggsisskygqyKKGDGiqrqvsgntgfALGDNGTLNlsgegSNNDYTNRAGDDFRTS------ 254
Cdd:PRK13484  147 SDAIGGVINIITKPVNN-----------QTWDG-----------VLGLGGIIQ-----EHGKFGNSTTNDFYLSgplikd 199
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 255 SIGSTTYGQQVFR------QGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETAAFYRPSNASNNIAAIYPNGYLP 328
Cdd:PRK13484  200 KLGLQLYGGMNYRkedsisQGTPAKDNKNITATLQFTPTESQKFVFEYGKNNQVHTLTPGESLDAWTMRGNLKQPNSKRE 279
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 329 lingTLEDTSLVAGLRGELADDWHYDVSANYGKNTYELRTKTINTSLGLNTPRSFDNGTLTNDQKQLGFdlsrefsAAWL 408
Cdd:PRK13484  280 ----THNSRSHWVAAWNAQGEILHPEIAVYQEKVIREVKSGKKDKYNHWDLNYESRKPEITNTIIDAKV-------TAFL 348
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 409 PHPVsVSFGAEYLHQGYQIEagqaesyfqtgsSGLGGfRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFG 488
Cdd:PRK13484  349 PENV-LTIGGQFQHAELRDD------------SATGK-KTTETQSVSIKQKAVFIENEYAATDSLALTGGLRLDNHEIYG 414
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 489 SNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFTFTSSQLIGNTIqeagtfpagsnvaqLLGAEDLKPEKSRNYSL 568
Cdd:PRK13484  415 SYWNPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPGFGTLTQGGASI--------------MYGNRDLKPETSVTEEI 480
                         570       580
                  ....*....|....*....|....*.
gi 1189288138 569 SLVLQPLDSLTVTADVYRIDIQDRIS 594
Cdd:PRK13484  481 GIIYSNDSGFSASATLFNTDFKNKLT 506
PRK13486 PRK13486
TonB-dependent receptor;
48-664 1.69e-14

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 77.37  E-value: 1.69e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  48 VIVTGTRAQERTASASLSpIDVISGDSLRSSGSSELGTVLaRLIPSINFPRPS-LVDGAELTrpaqLRGLSpdqvlvLVL 126
Cdd:PRK13486   28 MIVSASGYEKKLTNAAAS-VSVISQEELQSSQYHDLAEAL-RSVEGVDVESGTgKTGGLEIS----IRGMP------ASY 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 127 VLVLVNGKRRHTSAFVNLGG--AVGRGSAPadlnaiPLSAIDHIEVLRDGASARYGSDAIAGVINIILK-SADHGGSISS 203
Cdd:PRK13486   96 TLILIDGVRQGGSSDVTPNGfsAMNTGFMP------PLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRkNADKWLSSVN 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 204 KygqykkgdGIQRQVSGNtgfaLGDNGTLNLSGEGSNNDytnragDDFRTSSIGSTTYGQQVFRQGEPQTHEGKLQYNAE 283
Cdd:PRK13486  170 A--------GLNLQESNK----WGNSSQFNFWSSGPLVD------DSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 284 ysfndaAEFYSFGG-YSKRRGETAAFYRPSNASNNIaaiYPN--GYLPLINGTLEDTslvagLRGEladdwHYDVSANYG 360
Cdd:PRK13486  232 ------SQNYNLGArLDWKASEQDVLWFDMDTTRQR---YDNrdGQLGSLTGGYDRT-----LRYE-----RNKISAGYD 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 361 KN-TYELRTKTINTSLGLNTPRSFDNGTLTNDQKQLGFDlSREFSAAWLphpVSVSFGAEYLHQGYQIEAGqaeSYFQTG 439
Cdd:PRK13486  293 HTfTFGTWKSYLNWNETENKGRELVRSVLKRDKWGLAGQ-PRELKESNL---ILNSLLLTPLGESHLVTVG---GEFQSS 365
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 440 SSGLGGFRAADAGSYSRHNFAQYLDVETNLTEKLGVSAAVRHEDYSDFGSNVSGSLSARYDFTPQVALRGSVSTGFRAPS 519
Cdd:PRK13486  366 SMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPR 445
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138 520 LAQqnftftssqligntIQEAGTFPAGSNVAQLLGAEDLKPEKSRNYSLSLVLQPLDSLTVTADVYRIDIQDRISLSSnl 599
Cdd:PRK13486  446 MGQ--------------LHKGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTGFMTDFSNKIVSYS-- 509
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1189288138 600 VLNNTainylrsngvgdinytsaRYFTNATDTSTDGVDLVANYRYQFDngvrwNSTVGYNYNHTK 664
Cdd:PRK13486  510 INDNT------------------NSYVNSGKARLHGVEFAGTLPLWSE-----DVTLSLNYTWTR 551
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
59-187 1.21e-10

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 59.20  E-value: 1.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189288138  59 TASASLSPIDVISGDSLRSSGSSELGTVLARlIPSINFPRPSLVDGAELTrpaqLRGLSPDQVLVLVlvlvlvNGKRRHT 138
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSVSSGGGGGGSSIS----IRGFGSNRVLVLV------DGVPLNS 69
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1189288138 139 SafvnlggavgrGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAGV 187
Cdd:pfam07715  70 G-----------GGGSVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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