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Conserved domains on  [gi|1194632622|ref|WP_085964334|]
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MULTISPECIES: IS3 family transposase [Bacillus]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
15-383 1.22e-104

IS3 family transposase;


:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 312.96  E-value: 1.22e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  15 VVEMKHQGFKNKEIMDALGIkHVAQIKTWMKWYREGETYRFEQSigrqsahGKGLKRLTELEQKEL--EIRYLKAKINIA 92
Cdd:NF033516    7 VREVLEGGKSVAEVARELGI-SPSTLYRWRKKYRGGGEAADAGR-------LKELLTPEEEENRRLkrELAELRLENEIL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  93 GKVprnlKEVGGKEEIMKMIKEWQSIFTIAELCSIFNISRATYYRWKKQEKTVTNHEE----KTVIEICQHHKYRYGYRR 168
Cdd:NF033516   79 KKA----RKLLRPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDaelrARIREIFEESRGRYGYRR 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 169 VTACLRAQfNIVMNHKKVLRIMRKYNVLSRVRKKKKIFVL--GHEPVVAKNRIQRRFKATKPNEKWFTDITYLMFGNKTL 246
Cdd:NF033516  155 ITALLRRE-GIRVNHKRVYRLMRELGLLARRRRKRRPYTTdsGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 247 YFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVI-DTILHSDQGKVYTSKQFQTYAKEKGIITSMSRTGNCHD 325
Cdd:NF033516  234 YLAVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPeGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWD 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1194632622 326 NALIESFHSHLKSEGFYAQNIKqsNNASIIQTVDEYIHYYNNERIQRKLANMSPIAYR 383
Cdd:NF033516  314 NAVAESFFGTLKRECLYRRRFR--TLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
15-383 1.22e-104

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 312.96  E-value: 1.22e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  15 VVEMKHQGFKNKEIMDALGIkHVAQIKTWMKWYREGETYRFEQSigrqsahGKGLKRLTELEQKEL--EIRYLKAKINIA 92
Cdd:NF033516    7 VREVLEGGKSVAEVARELGI-SPSTLYRWRKKYRGGGEAADAGR-------LKELLTPEEEENRRLkrELAELRLENEIL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  93 GKVprnlKEVGGKEEIMKMIKEWQSIFTIAELCSIFNISRATYYRWKKQEKTVTNHEE----KTVIEICQHHKYRYGYRR 168
Cdd:NF033516   79 KKA----RKLLRPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDaelrARIREIFEESRGRYGYRR 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 169 VTACLRAQfNIVMNHKKVLRIMRKYNVLSRVRKKKKIFVL--GHEPVVAKNRIQRRFKATKPNEKWFTDITYLMFGNKTL 246
Cdd:NF033516  155 ITALLRRE-GIRVNHKRVYRLMRELGLLARRRRKRRPYTTdsGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 247 YFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVI-DTILHSDQGKVYTSKQFQTYAKEKGIITSMSRTGNCHD 325
Cdd:NF033516  234 YLAVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPeGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWD 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1194632622 326 NALIESFHSHLKSEGFYAQNIKqsNNASIIQTVDEYIHYYNNERIQRKLANMSPIAYR 383
Cdd:NF033516  314 NAVAESFFGTLKRECLYRRRFR--TLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
74-385 1.46e-77

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 241.60  E-value: 1.46e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  74 ELEQKELEIRYLKAKINIAGKVPRNLKEVGGKEEIMKMIKewqsiFTIAELCSIFNISRATYYRWKKQEKTVTNHEE--K 151
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRR-----RLLRLLRRRRARSRRRRRLRRPRSYRADEDAEllE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 152 TVIEICQHHKyRYGYRRVTACLRAQFnIVMNHKKVLRIMRKYNVLSRVRKKKKI-FVLGHEPVVAKNRIqrrFKATKPNE 230
Cdd:COG2801    76 RIKEIFAESP-RYGYRRITAELRREG-IAVNRKRVRRLMRELGLQARRRRKKKYtTYSGHGGPIAPNLL---FTATAPNQ 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 231 KWFTDITYLMFGNKTLYFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVID-TILHSDQGKVYTSKQFQTYAK 309
Cdd:COG2801   151 VWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKpLILHSDNGSQYTSKAYQELLK 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1194632622 310 EKGIITSMSRTGNCHDNALIESFHSHLKSEGFYAQNIKQSNNAsiIQTVDEYIHYYNNERIQRKLANMSPIAYRKH 385
Cdd:COG2801   231 KLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEA--REAIEEYIEFYNHERPHSSLGYLTPAEYEKQ 304
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 128-379 9.42e-48

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 163.50  E-value: 9.42e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 128 FNISRATYYRWKKQ----EKTVTNHEE-----KTVIEICQHHKYRYGYRRV-TACLRAQfnIVMNHKKVLRIMRKYNVLS 197
Cdd:PHA02517    1 LGIAPSTYYRCQQQrhhpDKRRARAQHddwlkSEILRVYDENHQVYGVRKVwRQLNREG--IRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 198 RVRKKKKIFVLGHEPVVAKNRIQRRFKATKPNEKWFTDITYLMFGNKTLYFSSIIDGFNNEIVSYKIGETQDVSLVLDTL 277
Cdd:PHA02517   79 VLRGKKVRTTISRKAVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 278 KEALR-KQNVIDTILHSDQGKVYTSKQFQTYAKEKGIITSMSRTGNCHDNALIESFHSHLKSEGFYAQNIKQSNNASIIQ 356
Cdd:PHA02517  159 EQALWaRGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELAT 238

                         250       260
                  ....*....|....*....|...
gi 1194632622 357 TvdEYIHYYNNERIQRKLANMSP 379
Cdd:PHA02517  239 L--EWVAWYNNRRLHERLGYTPP 259
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 228-323 1.24e-24

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 1.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 228 PNEKWFTDITYL--MFGNKTLYFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVIDTILHSDQGKVYTSKQFQ 305
Cdd:pfam00665   1 PNQLWQGDFTYIriPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLIIHSDNGSEYTSKAFR 80

                          90
                  ....*....|....*...
gi 1194632622 306 TYAKEKGIITSMSRTGNC 323
Cdd:pfam00665  81 EFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 104-380 9.07e-22

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 93.81  E-value: 9.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 104 GKEEIMKMIKEWQSifTIAELCSIFNISRATYYRWKKQEKT-------------------VTNHEEKTVIEICQHHkyRY 164
Cdd:NF033577    1 GRLELVRLVLEDGW--SVREAARRFGISRKTVYKWLKRYRAggeeglidrsrrphrsprrTSPETEARILALRREL--RL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 165 GYRRVTACLRAQFNIVmNHKKVLRIMRKYNvLSRVRKKKKifvlghepvvaKNRIQRRFKATKPNEKWFTDITYL-MFGN 243
Cdd:NF033577   77 GPRRIAYELERQGPGV-SRSTVHRILRRHG-LSRLRALDR-----------KTGKVKRYERAHPGELWHIDIKKLgRIPD 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 244 KT-LYFSSIIDGFNNEIVSyKIGETQDVSLVLDTLKEALRKQNV-IDTILhSDQGKVYTSK--QFQTYAKEKGIITSMSR 319
Cdd:NF033577  144 VGrLYLHTAIDDHSRFAYA-ELYPDETAETAADFLRRAFAEHGIpIRRVL-TDNGSEFRSRahGFELALAELGIEHRRTR 221

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1194632622 320 TGNCHDNALIESFHSHLKSEGFYAQNIkqSNNASIIQTVDEYIHYYNNERIQRKLANMSPI 380
Cdd:NF033577  222 PYHPQTNGKVERFHRTLKDEFAYARPY--ESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
15-383 1.22e-104

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 312.96  E-value: 1.22e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  15 VVEMKHQGFKNKEIMDALGIkHVAQIKTWMKWYREGETYRFEQSigrqsahGKGLKRLTELEQKEL--EIRYLKAKINIA 92
Cdd:NF033516    7 VREVLEGGKSVAEVARELGI-SPSTLYRWRKKYRGGGEAADAGR-------LKELLTPEEEENRRLkrELAELRLENEIL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  93 GKVprnlKEVGGKEEIMKMIKEWQSIFTIAELCSIFNISRATYYRWKKQEKTVTNHEE----KTVIEICQHHKYRYGYRR 168
Cdd:NF033516   79 KKA----RKLLRPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDaelrARIREIFEESRGRYGYRR 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 169 VTACLRAQfNIVMNHKKVLRIMRKYNVLSRVRKKKKIFVL--GHEPVVAKNRIQRRFKATKPNEKWFTDITYLMFGNKTL 246
Cdd:NF033516  155 ITALLRRE-GIRVNHKRVYRLMRELGLLARRRRKRRPYTTdsGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 247 YFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVI-DTILHSDQGKVYTSKQFQTYAKEKGIITSMSRTGNCHD 325
Cdd:NF033516  234 YLAVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPeGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWD 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1194632622 326 NALIESFHSHLKSEGFYAQNIKqsNNASIIQTVDEYIHYYNNERIQRKLANMSPIAYR 383
Cdd:NF033516  314 NAVAESFFGTLKRECLYRRRFR--TLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
74-385 1.46e-77

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 241.60  E-value: 1.46e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  74 ELEQKELEIRYLKAKINIAGKVPRNLKEVGGKEEIMKMIKewqsiFTIAELCSIFNISRATYYRWKKQEKTVTNHEE--K 151
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRR-----RLLRLLRRRRARSRRRRRLRRPRSYRADEDAEllE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 152 TVIEICQHHKyRYGYRRVTACLRAQFnIVMNHKKVLRIMRKYNVLSRVRKKKKI-FVLGHEPVVAKNRIqrrFKATKPNE 230
Cdd:COG2801    76 RIKEIFAESP-RYGYRRITAELRREG-IAVNRKRVRRLMRELGLQARRRRKKKYtTYSGHGGPIAPNLL---FTATAPNQ 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 231 KWFTDITYLMFGNKTLYFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVID-TILHSDQGKVYTSKQFQTYAK 309
Cdd:COG2801   151 VWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKpLILHSDNGSQYTSKAYQELLK 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1194632622 310 EKGIITSMSRTGNCHDNALIESFHSHLKSEGFYAQNIKQSNNAsiIQTVDEYIHYYNNERIQRKLANMSPIAYRKH 385
Cdd:COG2801   231 KLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEA--REAIEEYIEFYNHERPHSSLGYLTPAEYEKQ 304
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 128-379 9.42e-48

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 163.50  E-value: 9.42e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 128 FNISRATYYRWKKQ----EKTVTNHEE-----KTVIEICQHHKYRYGYRRV-TACLRAQfnIVMNHKKVLRIMRKYNVLS 197
Cdd:PHA02517    1 LGIAPSTYYRCQQQrhhpDKRRARAQHddwlkSEILRVYDENHQVYGVRKVwRQLNREG--IRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 198 RVRKKKKIFVLGHEPVVAKNRIQRRFKATKPNEKWFTDITYLMFGNKTLYFSSIIDGFNNEIVSYKIGETQDVSLVLDTL 277
Cdd:PHA02517   79 VLRGKKVRTTISRKAVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 278 KEALR-KQNVIDTILHSDQGKVYTSKQFQTYAKEKGIITSMSRTGNCHDNALIESFHSHLKSEGFYAQNIKQSNNASIIQ 356
Cdd:PHA02517  159 EQALWaRGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELAT 238

                         250       260
                  ....*....|....*....|...
gi 1194632622 357 TvdEYIHYYNNERIQRKLANMSP 379
Cdd:PHA02517  239 L--EWVAWYNNRRLHERLGYTPP 259
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 228-323 1.24e-24

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 96.61  E-value: 1.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 228 PNEKWFTDITYL--MFGNKTLYFSSIIDGFNNEIVSYKIGETQDVSLVLDTLKEALRKQNVIDTILHSDQGKVYTSKQFQ 305
Cdd:pfam00665   1 PNQLWQGDFTYIriPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLIIHSDNGSEYTSKAFR 80

                          90
                  ....*....|....*...
gi 1194632622 306 TYAKEKGIITSMSRTGNC 323
Cdd:pfam00665  81 EFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 104-380 9.07e-22

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 93.81  E-value: 9.07e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 104 GKEEIMKMIKEWQSifTIAELCSIFNISRATYYRWKKQEKT-------------------VTNHEEKTVIEICQHHkyRY 164
Cdd:NF033577    1 GRLELVRLVLEDGW--SVREAARRFGISRKTVYKWLKRYRAggeeglidrsrrphrsprrTSPETEARILALRREL--RL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 165 GYRRVTACLRAQFNIVmNHKKVLRIMRKYNvLSRVRKKKKifvlghepvvaKNRIQRRFKATKPNEKWFTDITYL-MFGN 243
Cdd:NF033577   77 GPRRIAYELERQGPGV-SRSTVHRILRRHG-LSRLRALDR-----------KTGKVKRYERAHPGELWHIDIKKLgRIPD 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 244 KT-LYFSSIIDGFNNEIVSyKIGETQDVSLVLDTLKEALRKQNV-IDTILhSDQGKVYTSK--QFQTYAKEKGIITSMSR 319
Cdd:NF033577  144 VGrLYLHTAIDDHSRFAYA-ELYPDETAETAADFLRRAFAEHGIpIRRVL-TDNGSEFRSRahGFELALAELGIEHRRTR 221

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1194632622 320 TGNCHDNALIESFHSHLKSEGFYAQNIkqSNNASIIQTVDEYIHYYNNERIQRKLANMSPI 380
Cdd:NF033577  222 PYHPQTNGKVERFHRTLKDEFAYARPY--ESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 147-203 1.32e-15

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 70.68  E-value: 1.32e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1194632622 147 NHEEKTVIEICQHHKYRYGYRRVTACLRAQFNIVMNHKKVLRIMRKYNVLSRVRKKK 203
Cdd:pfam13276   4 DELLEAIREIFEESRGTYGYRRITAELRREGGIRVNRKRVARLMRELGLRARRRRKR 60
rve_2 pfam13333
Integrase core domain;
330-386 3.08e-07

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 46.87  E-value: 3.08e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1194632622 330 ESFHSHLKSEGFYAQNIKqsNNASIIQTVDEYIHYYNNERIQrklaNMSPIAYRKHV 386
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFK--TLEELELAIFDYIEWYNNKRLK----GLSPVQYRNQS 51
rve_3 pfam13683
Integrase core domain;
312-379 5.80e-07

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 46.44  E-value: 5.80e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1194632622 312 GIITSMSRTGNCHDNALIESFHSHLKSEgFYAQNIKQSNNASIIQTvDEYIHYYNNERIQRKLANMSP 379
Cdd:pfam13683   2 GIEISYIAPGKPMQNGLVESFNGTLRDE-CLNEHLFSSLAEARALL-AAWREDYNTERPHSSLGYRTP 67
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
 146-385 1.41e-05

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 46.25  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 146 TNHEEKTVIEICQHHKY----RYGYRRVTACLRAQFNI----VMNHKKVLRIMRKYNVLsrvrkkkkifvLGHEPVV--A 215
Cdd:PRK09409   44 SRHTDDTDVLLRIHHVIgelpTYGYRRVWALLRRQAELdgmpAINAKRVYRIMRQNALL-----------LERKPAVppS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 216 KNRIQRRFKATKPNEKWFTD-------------ITYLM--FGNKTLYFSSIIDGFNNEIvsykigetqdvslVLDTLKEA 280
Cdd:PRK09409  113 KRAHTGRVAVKESNQRWCSDgfefccdngerlrVTFALdcCDREALHWAVTTGGFNSET-------------VQDVMLGA 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622 281 LRKQNVIDTILH-----SDQGKVYTSKQFQTYAKEKGIITSMSRTGNCHDNALIESFHSHLKSEgfYAQNIKQSNNASII 355
Cdd:PRK09409  180 VERRFGNDLPSSpvewlTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRD--YISIMPKPDGLTAA 257

                         250       260       270
                  ....*....|....*....|....*....|
gi 1194632622 356 QTVDEYIHYYNNERIQRKLANMSPIAYRKH 385
Cdd:PRK09409  258 KNLAEAFEHYNEWHPHSALGYRSPREYLRQ 287
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-91 1.44e-04

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 40.29  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622   1 MGKK-THYPAEIKWKVVEMKHQGFKN-KEIMDALGIkHVAQIKTWMKWYREGETYRFEQSiGRQSAHGKGLKRLT-ELEQ 77
Cdd:COG2963     1 MSKKrRRYSPEFKAEAVRLVLEGGASvAEVARELGI-SPSTLYRWVRQYREGGLGGFPGD-GRTTPEQAEIRRLRkELRR 78

                          90
                  ....*....|....
gi 1194632622  78 KELEIRYLKAKINI 91
Cdd:COG2963    79 LEMENDILKKAAAL 92
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 110-141 8.89e-04

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 36.80  E-value: 8.89e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1194632622 110 KMIKEWQSIFTIAELCSIFNISRATYYRWKKQ 141
Cdd:pfam13518   4 KIVLLALEGESIKEAARLFGISRSTVYRWIRR 35
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
 70-204 6.01e-03

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 38.29  E-value: 6.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194632622  70 KRLTELEQKELEIRYLKAKiniagkvprnLKEVGGKEEIMKMIKEWQSIftiAELCSIFNISRATYYRWKKQ-------- 141
Cdd:COG3415     3 LTLTEEERRDLEKLLRKTK----------DAREARRLRAVLLLAEGLSV---REIAERLGVSRSTVYRWLKRyregglag 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1194632622 142 ---------EKTVTNHEEKTVIEICQHH----KYRYGYRRVTACLRAQFNIVMNHKKVLRIMRKYNvLSRVRKKKK 204
Cdd:COG3415    70 lkdrprggrPSKLSDEQRERLLELLREKspdqGSRWTLAELAELLEEEFGVEVSPSTVRRLLKRLG-LSYKKPRPR 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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