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Conserved domains on  [gi|1194648242|ref|WP_085976999|]
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IS3 family transposase [Rubrivivax benzoatilyticus]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-357 6.21e-110

IS3 family transposase;


:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 326.06  E-value: 6.21e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242   9 EQIIGFLRQA-EAGMAVAEICRRGGFSDATFYKWRSKF-GGMEASDAKRLREL----EEENAKLKKLLAEAHLDMHALKS 82
Cdd:NF033516    1 EFKLEAVREVlEGGKSVAEVARELGISPSTLYRWRKKYrGGGEAADAGRLKELltpeEEENRRLKRELAELRLENEILKK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  83 VlgGKALAPRAKREAISRLvqEHQLSERRACRLVGLSRDSY-----RHPPEADAATRELAARIVEIAHVRR-RFGYRRIH 156
Cdd:NF033516   81 A--RKLLRPAVKYALIDAL--RGEYSVRRACRVLGVSRSTYyywrkRPPSRRAPDDAELRARIREIFEESRgRYGYRRIT 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 157 DLLRPEFPGVNHKRVWRLYAAANLAV---RKRKKVRRPPAERVPLQ--------AARSVNEVWSMDFVSDSLANGRrLKC 225
Cdd:NF033516  157 ALLRREGIRVNHKRVYRLMRELGLLArrrRKRRPYTTDSGHVHPVApnllnrqfTATRPNQVWVTDITYIRTAEGW-LYL 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 226 LTVADDFSHECVDIAVDYGISGEYVTRLLDRAAVFRGYPAAV--RTDNGPEFTSRAFIAWAQRHHIRHLLIEPGRPMQNG 303
Cdd:NF033516  236 AVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLilHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNA 315
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 304 YIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFA 357
Cdd:NF033516  316 VAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-357 6.21e-110

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 326.06  E-value: 6.21e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242   9 EQIIGFLRQA-EAGMAVAEICRRGGFSDATFYKWRSKF-GGMEASDAKRLREL----EEENAKLKKLLAEAHLDMHALKS 82
Cdd:NF033516    1 EFKLEAVREVlEGGKSVAEVARELGISPSTLYRWRKKYrGGGEAADAGRLKELltpeEEENRRLKRELAELRLENEILKK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  83 VlgGKALAPRAKREAISRLvqEHQLSERRACRLVGLSRDSY-----RHPPEADAATRELAARIVEIAHVRR-RFGYRRIH 156
Cdd:NF033516   81 A--RKLLRPAVKYALIDAL--RGEYSVRRACRVLGVSRSTYyywrkRPPSRRAPDDAELRARIREIFEESRgRYGYRRIT 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 157 DLLRPEFPGVNHKRVWRLYAAANLAV---RKRKKVRRPPAERVPLQ--------AARSVNEVWSMDFVSDSLANGRrLKC 225
Cdd:NF033516  157 ALLRREGIRVNHKRVYRLMRELGLLArrrRKRRPYTTDSGHVHPVApnllnrqfTATRPNQVWVTDITYIRTAEGW-LYL 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 226 LTVADDFSHECVDIAVDYGISGEYVTRLLDRAAVFRGYPAAV--RTDNGPEFTSRAFIAWAQRHHIRHLLIEPGRPMQNG 303
Cdd:NF033516  236 AVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLilHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNA 315
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 304 YIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFA 357
Cdd:NF033516  316 VAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
61-364 5.04e-72

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 227.34  E-value: 5.04e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  61 EENAKLKKLLAEAHLDMHALKSVLGGKALAPRAKREAISRLVQEHQLSERRACRLVGLSRDSYRHPPEADAatrELAARI 140
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRSYRADEDA---ELLERI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 141 VEIAHVRRRFGYRRIHDLLRPEFPGVNHKRVWRLYAAANLAVRKRKKVRR--------PPAERVPLQAARsVNEVWSMDF 212
Cdd:COG2801    78 KEIFAESPRYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYttysghggPIAPNLLFTATA-PNQVWVTDI 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 213 VSDSLANGRrLKCLTVADDFSHECVDIAVDYGISGEYVTRLLDRAAVFRGY--PAAVRTDNGPEFTSRAFIAWAQRHHIR 290
Cdd:COG2801   157 TYIPTAEGW-LYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPpkPLILHSDNGSQYTSKAYQELLKKLGIT 235
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 291 HLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFAEQQRRHA 364
Cdd:COG2801   236 QSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAEYEKQLAAAA 309
rve_3 pfam13683
Integrase core domain;
289-353 1.08e-34

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 122.32  E-value: 1.08e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1194648242 289 IRHLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAP 353
Cdd:pfam13683   3 IEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
transpos_IS481 NF033577
IS481 family transposase; null
94-354 8.24e-31

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 118.46  E-value: 8.24e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  94 KREAISRLVQEHQLSERRACRLVGLSRDSY-----------------------RHPPEADAATRElaaRIVEIaHVRRRF 150
Cdd:NF033577    1 GRLELVRLVLEDGWSVREAARRFGISRKTVykwlkryraggeeglidrsrrphRSPRRTSPETEA---RILAL-RRELRL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 151 GYRRIHDLLRPEFPGVNHKRVWRLYAAANLAvrKRKKVRRPPAERVPLQAARSvNEVWSMDF--VSDsLANGRRLKCLTV 228
Cdd:NF033577   77 GPRRIAYELERQGPGVSRSTVHRILRRHGLS--RLRALDRKTGKVKRYERAHP-GELWHIDIkkLGR-IPDVGRLYLHTA 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 229 ADDFS----HECVDIAvdygiSGEYVTRLLDRAAVFRGYP-AAVRTDNGPEFTSRA--FIAWAQRHHIRHLLIEPGRPMQ 301
Cdd:NF033577  153 IDDHSrfayAELYPDE-----TAETAADFLRRAFAEHGIPiRRVLTDNGSEFRSRAhgFELALAELGIEHRRTRPYHPQT 227
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1194648242 302 NGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPA 354
Cdd:NF033577  228 NGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
PHA02517 PHA02517
putative transposase OrfB; Reviewed
117-354 8.15e-15

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 73.75  E-value: 8.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 117 GLSRDSYRH-------PPEADAATRE---LAARIVEI-AHVRRRFGYRRIHDLLRPEFPGVNHKRVWRLYAAANLAVRKR 185
Cdd:PHA02517    2 GIAPSTYYRcqqqrhhPDKRRARAQHddwLKSEILRVyDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVLR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 186 KKVRRPPAERVPLQ---------AARSVNEVWSMDFVSdsLANGRRLKCL-TVADDFSHECVDIAVDYGISGEYVTRLLD 255
Cdd:PHA02517   82 GKKVRTTISRKAVAapdrvnrqfVATRPNQLWVADFTY--VSTWQGWVYVaFIIDVFARRIVGWRVSSSMDTDFVLDALE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 256 RAAVFRGYPAAV--RTDNGPEFTSRAFIAWAQRHHIRHLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIA 333
Cdd:PHA02517  160 QALWARGRPGGLihHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATL 239
                         250       260
                  ....*....|....*....|.
gi 1194648242 334 AWRRDYNEVRPHSSIGRIAPA 354
Cdd:PHA02517  240 EWVAWYNNRRLHERLGYTPPA 260
transpos_IS21 NF033546
IS21 family transposase;
100-360 8.77e-05

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 43.74  E-value: 8.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 100 RLVQEHQLSERRACRLVGLSRDSYR-----HPPEADAATRELAARIVEIAHVRRRfgyrrIHDLLR--PEFPGVNHKRVW 172
Cdd:NF033546    2 RLLFRQGLSIREIARELGISRNTVRkylrrAGLDEPPKYERRPPRPSKLDPFEPY-----IPDWLEahLRKPGVTATLLW 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 173 RLYAAANLA---------VRKRKKVRRPPAERVPLQ-AARSVNEV-WSMDFVSDSLANGRRLKCLTVADDFSHECVDIAV 241
Cdd:NF033546   77 EELRAEGYPgsystvrryVRRWRAEQGPAKVFVRLEhAPGEQAQVdFGEATVVVTGGTGKILHVFVAVLGYSRYTYVEAT 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 242 dYGISGEYVTRLLDRA-AVFRGYPAAVRTDN------------GPEFTsRAFIAWAQRHHIRHLLIEPGRPMQNGYIESF 308
Cdd:NF033546  157 -PSESQEDLLDGHQRAfEFFGGVPREIVYDNlktavdkrdryeEPRLN-PRFAAFAAHYGFEPRPCRPYRPQEKGKVERA 234
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 309 NGKFRDECLNE--HWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFAEQQ 360
Cdd:NF033546  235 VGYVRRWFLRLrgRRFESLAELNAALAEWLAELANQRPHGTTGGSPAERFEEER 288
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-357 6.21e-110

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 326.06  E-value: 6.21e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242   9 EQIIGFLRQA-EAGMAVAEICRRGGFSDATFYKWRSKF-GGMEASDAKRLREL----EEENAKLKKLLAEAHLDMHALKS 82
Cdd:NF033516    1 EFKLEAVREVlEGGKSVAEVARELGISPSTLYRWRKKYrGGGEAADAGRLKELltpeEEENRRLKRELAELRLENEILKK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  83 VlgGKALAPRAKREAISRLvqEHQLSERRACRLVGLSRDSY-----RHPPEADAATRELAARIVEIAHVRR-RFGYRRIH 156
Cdd:NF033516   81 A--RKLLRPAVKYALIDAL--RGEYSVRRACRVLGVSRSTYyywrkRPPSRRAPDDAELRARIREIFEESRgRYGYRRIT 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 157 DLLRPEFPGVNHKRVWRLYAAANLAV---RKRKKVRRPPAERVPLQ--------AARSVNEVWSMDFVSDSLANGRrLKC 225
Cdd:NF033516  157 ALLRREGIRVNHKRVYRLMRELGLLArrrRKRRPYTTDSGHVHPVApnllnrqfTATRPNQVWVTDITYIRTAEGW-LYL 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 226 LTVADDFSHECVDIAVDYGISGEYVTRLLDRAAVFRGYPAAV--RTDNGPEFTSRAFIAWAQRHHIRHLLIEPGRPMQNG 303
Cdd:NF033516  236 AVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLilHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNA 315
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 304 YIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFA 357
Cdd:NF033516  316 VAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
61-364 5.04e-72

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 227.34  E-value: 5.04e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  61 EENAKLKKLLAEAHLDMHALKSVLGGKALAPRAKREAISRLVQEHQLSERRACRLVGLSRDSYRHPPEADAatrELAARI 140
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRSYRADEDA---ELLERI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 141 VEIAHVRRRFGYRRIHDLLRPEFPGVNHKRVWRLYAAANLAVRKRKKVRR--------PPAERVPLQAARsVNEVWSMDF 212
Cdd:COG2801    78 KEIFAESPRYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYttysghggPIAPNLLFTATA-PNQVWVTDI 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 213 VSDSLANGRrLKCLTVADDFSHECVDIAVDYGISGEYVTRLLDRAAVFRGY--PAAVRTDNGPEFTSRAFIAWAQRHHIR 290
Cdd:COG2801   157 TYIPTAEGW-LYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPpkPLILHSDNGSQYTSKAYQELLKKLGIT 235
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 291 HLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFAEQQRRHA 364
Cdd:COG2801   236 QSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAEYEKQLAAAA 309
rve_3 pfam13683
Integrase core domain;
289-353 1.08e-34

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 122.32  E-value: 1.08e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1194648242 289 IRHLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAP 353
Cdd:pfam13683   3 IEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
transpos_IS481 NF033577
IS481 family transposase; null
94-354 8.24e-31

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 118.46  E-value: 8.24e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  94 KREAISRLVQEHQLSERRACRLVGLSRDSY-----------------------RHPPEADAATRElaaRIVEIaHVRRRF 150
Cdd:NF033577    1 GRLELVRLVLEDGWSVREAARRFGISRKTVykwlkryraggeeglidrsrrphRSPRRTSPETEA---RILAL-RRELRL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 151 GYRRIHDLLRPEFPGVNHKRVWRLYAAANLAvrKRKKVRRPPAERVPLQAARSvNEVWSMDF--VSDsLANGRRLKCLTV 228
Cdd:NF033577   77 GPRRIAYELERQGPGVSRSTVHRILRRHGLS--RLRALDRKTGKVKRYERAHP-GELWHIDIkkLGR-IPDVGRLYLHTA 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 229 ADDFS----HECVDIAvdygiSGEYVTRLLDRAAVFRGYP-AAVRTDNGPEFTSRA--FIAWAQRHHIRHLLIEPGRPMQ 301
Cdd:NF033577  153 IDDHSrfayAELYPDE-----TAETAADFLRRAFAEHGIPiRRVLTDNGSEFRSRAhgFELALAELGIEHRRTRPYHPQT 227
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1194648242 302 NGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPA 354
Cdd:NF033577  228 NGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
204-299 7.33e-25

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 97.00  E-value: 7.33e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 204 VNEVWSMDFVSDSLAN-GRRLKCLTVADDFSHECVDIAVDYGISGEYVTRLLDRAAVFRGY-PAAVRTDNGPEFTSRAFI 281
Cdd:pfam00665   1 PNQLWQGDFTYIRIPGgGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGvPLIIHSDNGSEYTSKAFR 80
                          90
                  ....*....|....*...
gi 1194648242 282 AWAQRHHIRHLLIEPGRP 299
Cdd:pfam00665  81 EFLKDLGIKPSFSRPGNP 98
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
2-71 6.72e-17

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 74.70  E-value: 6.72e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1194648242   2 RKSKFSEEQIIGFLRQA-EAGMAVAEICRRGGFSDATFYKWRSKF-GGMEASDAK-RLRELEEENAKLKKLLA 71
Cdd:pfam01527   3 KRRRFSEEFKLRAVKEVlEPGRTVKEVARRHGVSPNTLYQWRRQYeGGMGASPARpRLTALEEENRRLKRELA 75
PHA02517 PHA02517
putative transposase OrfB; Reviewed
117-354 8.15e-15

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 73.75  E-value: 8.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 117 GLSRDSYRH-------PPEADAATRE---LAARIVEI-AHVRRRFGYRRIHDLLRPEFPGVNHKRVWRLYAAANLAVRKR 185
Cdd:PHA02517    2 GIAPSTYYRcqqqrhhPDKRRARAQHddwLKSEILRVyDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVLR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 186 KKVRRPPAERVPLQ---------AARSVNEVWSMDFVSdsLANGRRLKCL-TVADDFSHECVDIAVDYGISGEYVTRLLD 255
Cdd:PHA02517   82 GKKVRTTISRKAVAapdrvnrqfVATRPNQLWVADFTY--VSTWQGWVYVaFIIDVFARRIVGWRVSSSMDTDFVLDALE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 256 RAAVFRGYPAAV--RTDNGPEFTSRAFIAWAQRHHIRHLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIA 333
Cdd:PHA02517  160 QALWARGRPGGLihHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATL 239
                         250       260
                  ....*....|....*....|.
gi 1194648242 334 AWRRDYNEVRPHSSIGRIAPA 354
Cdd:PHA02517  240 EWVAWYNNRRLHERLGYTPPA 260
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
150-360 7.31e-09

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 56.28  E-value: 7.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 150 FGYRRIHDLLRPE-----FPGVNHKRVWRLYAAANLAVRKRKKVrrPPAERVPLQ--AARSVNEVWSMDFVSDSLANGRR 222
Cdd:PRK14702   27 YGYRRVWALLRRQaeldgMPAINAKRVYRLMRQNALLLERKPAV--PPSKRAHTGrvAVKESNQRWCSDGFEFCCDNGER 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 223 LKCLTVADDFSHECVDIAVDY-GISGEYVTRLLDRAAVFR------GYPAAVRTDNGpeftsRAFIAWAQRHHIRHLLIE 295
Cdd:PRK14702  105 LRVTFALDCCDREALHWAVTTgGFNSETVQDVMLGAVERRfgndlpSSPVEWLTDNG-----SCYRANETRQFARMLGLE 179
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 296 PGR-----PMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFAEQQ 360
Cdd:PRK14702  180 PKNtavrsPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQR 249
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
150-360 1.36e-08

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 55.49  E-value: 1.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 150 FGYRRIHDLLRPE-----FPGVNHKRVWRLYAAANLAVRKRKKVrrPPAERVPLQ--AARSVNEVWSMDFVSDSLANGRR 222
Cdd:PRK09409   66 YGYRRVWALLRRQaeldgMPAINAKRVYRIMRQNALLLERKPAV--PPSKRAHTGrvAVKESNQRWCSDGFEFCCDNGER 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 223 LKCLTVADDFSHECVDIAVDYG-ISGEYVTRLLDRAAVFR------GYPAAVRTDNGpeftsRAFIAWAQRHHIRHLLIE 295
Cdd:PRK09409  144 LRVTFALDCCDREALHWAVTTGgFNSETVQDVMLGAVERRfgndlpSSPVEWLTDNG-----SCYRANETRQFARMLGLE 218
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 296 PGR-----PMQNGYIESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFAEQQ 360
Cdd:PRK09409  219 PKNtavrsPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQR 288
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
134-187 2.41e-07

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 47.18  E-value: 2.41e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1194648242 134 RELAARIVEIAHV-RRRFGYRRIHDLLRPEFPG-VNHKRVWRLYAAANLAVRKRKK 187
Cdd:pfam13276   4 DELLEAIREIFEEsRGTYGYRRITAELRREGGIrVNRKRVARLMRELGLRARRRRK 59
transpos_IS21 NF033546
IS21 family transposase;
100-360 8.77e-05

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 43.74  E-value: 8.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 100 RLVQEHQLSERRACRLVGLSRDSYR-----HPPEADAATRELAARIVEIAHVRRRfgyrrIHDLLR--PEFPGVNHKRVW 172
Cdd:NF033546    2 RLLFRQGLSIREIARELGISRNTVRkylrrAGLDEPPKYERRPPRPSKLDPFEPY-----IPDWLEahLRKPGVTATLLW 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 173 RLYAAANLA---------VRKRKKVRRPPAERVPLQ-AARSVNEV-WSMDFVSDSLANGRRLKCLTVADDFSHECVDIAV 241
Cdd:NF033546   77 EELRAEGYPgsystvrryVRRWRAEQGPAKVFVRLEhAPGEQAQVdFGEATVVVTGGTGKILHVFVAVLGYSRYTYVEAT 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 242 dYGISGEYVTRLLDRA-AVFRGYPAAVRTDN------------GPEFTsRAFIAWAQRHHIRHLLIEPGRPMQNGYIESF 308
Cdd:NF033546  157 -PSESQEDLLDGHQRAfEFFGGVPREIVYDNlktavdkrdryeEPRLN-PRFAAFAAHYGFEPRPCRPYRPQEKGKVERA 234
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 309 NGKFRDECLNE--HWFQSLAQARQTIAAWRRDYNEVRPHSSIGRIAPARFAEQQ 360
Cdd:NF033546  235 VGYVRRWFLRLrgRRFESLAELNAALAEWLAELANQRPHGTTGGSPAERFEEER 288
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
19-364 1.32e-04

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 43.33  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  19 EAGMAVAEICRRGGFSDATFYKWRSKFGGMEASDAKRLRELEEENAK----LKKLLAEAHLDMHALKSVLggKALAPrak 94
Cdd:COG2826    20 KAGLSVREIARRLGRSPSTISRELKRNSGRRGYRAEGAQRLAEDRRRrpkrKRKLATTPELRAYVEEKLR--KKWSP--- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242  95 rEAIS-RLVQEHQLSERracrlvgLSRDS-YRHPpEADAATRELaariveIAHVRRRFGYRRIHdllrpefpgvnhkrvw 172
Cdd:COG2826    95 -EQIAgRLKREDDPGMR-------VSHETiYRYI-YAGGLRKDL------YRPLRRKRKRRRPR---------------- 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 173 rlyaAANLAVRKRKKVRRPPAERvPLQAA-RSVNEVWSMDFVSdslanGRRLKC--LTVADDFSHECVDIAVDyGISGEY 249
Cdd:COG2826   144 ----GRTRKRRGKIPDRRSISER-PAEVEdRAEPGHWEGDLII-----GKRGKSalLTLVERKSRFVILLKLP-DKTAES 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242 250 VTRLLDRAavFRGYPAAVR----TDNGPEFTSRAFIAwaQRHHIRHLLIEPGRPMQNGYIESFNGKFRDECLNEHWFQSL 325
Cdd:COG2826   213 VADALIRL--LRKLPAFLRksitTDNGKEFADHKEIE--AALGIKVYFADPYSPWQRGTNENTNGLLRQYFPKGTDFSTV 288
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1194648242 326 AQarQTIAAWRRDYNEvRPHSSIGRIAPA-RFAEQQRRHA 364
Cdd:COG2826   289 TQ--EELDAIADRLNN-RPRKCLGYKTPAeVFAEELAALA 325
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-81 9.41e-04

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 37.98  E-value: 9.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1194648242   2 RKSKFSEEQIIGFLRQA-EAGMAVAEICRRGGFSDATFYKWRSKF---GGMEASDAKRLRELEEENAKLKKLLAEAHLDM 77
Cdd:COG2963     4 KRRRYSPEFKAEAVRLVlEGGASVAEVARELGISPSTLYRWVRQYregGLGGFPGDGRTTPEQAEIRRLRKELRRLEMEN 83

                  ....
gi 1194648242  78 HALK 81
Cdd:COG2963    84 DILK 87
rve_2 pfam13333
Integrase core domain;
306-359 4.69e-03

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 34.93  E-value: 4.69e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1194648242 306 ESFNGKFRDECLNEHWFQSLAQARQTIAAWRRDYNEVRphssIGRIAPARFAEQ 359
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIEWYNNKR----LKGLSPVQYRNQ 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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