|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
2-467 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 636.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 2 MLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAE 77
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKElgrpVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 78 GHIDFKTGERVTIVGKPEqETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNV 157
Cdd:COG0469 81 GPVELKKGDTFTLTTDDV-EGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 158 PGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADGVM 237
Cdd:COG0469 160 PGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 238 VARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 317
Cdd:COG0469 240 VARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 318 VEAVKTMAKIAAQAEKDKMEENDIPIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVLAI 397
Cdd:COG0469 320 VEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1199513147 398 CYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSG---GKKGThTSFLEINQV 467
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGvpvGVPGT-TNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-458 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 634.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 1 MMLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASA 76
Cdd:PRK05826 1 RMLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKlgrpVAILLDLKGPKIRVGKFK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 77 EGHIDFKTGERVTIVGKPEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVN 156
Cdd:PRK05826 81 EGKITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 157 VPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQS-DIQIIAKIENQEGVDNIDEILEVADG 235
Cdd:PRK05826 161 IPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCpHAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 236 VMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 316 YPVEAVKTMAKIAAQAEKDKmEENDIPIPLTPDNTDVTSFLAKQAVRATT-LMPIRAIITDSFSGRTARNLAAFRGKYPV 394
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKEF-SINLSKHRLDRQFDRIDEAIAMSAMYAANhLKGVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1199513147 395 LAICYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSGGKKGTH 458
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTA 463
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
4-464 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 514.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 4 KQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVS----NRIGILMDTKGPEVRTTASAEGH 79
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAeklgRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 80 IDFKTGERVTIVGKP-EQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNVP 158
Cdd:TIGR01064 81 VKLKKGDKVIITTDDiKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 159 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAH-QSDIQIIAKIENQEGVDNIDEILEVADGVM 237
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 238 VARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 317
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 318 VEAVKTMAKIAAQAEK--DKMEENDIPIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVL 395
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKalAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1199513147 396 AICYKEKTMRHLALSYGVEAIYMPEKAN-GQEYYFTALRKLLSDGVLTPKEMVAYLSGGKKGT--HTSFLEI 464
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGegGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
3-464 |
1.11e-161 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 466.41 E-value: 1.11e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 3 LKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAEG 78
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKtggpVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 H-IDFKTGERVTIVGKP-EQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNED-TLFCEVCNDATLGNRKSV 155
Cdd:cd00288 81 KdISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 156 NVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADG 235
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 236 VMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 316 YPVEAVKTMAKIAAQAEKdKMEENDI---PIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKY 392
Cdd:cd00288 321 YPVEAVKAMARICLEAEK-ALSHRVLfneMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1199513147 393 PVLAICYKEKTMRHLALSYGVEAIYMPEK----ANGQEYYFT-ALRKLLSDGVLTPKEMVAYLSGGKKGT-HTSFLEI 464
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwQEDTDARLKaAVNVAKEKGLLKKGDLVVVVQGWPVGSgSTNTMRI 477
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
3-333 |
1.42e-136 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 397.51 E-value: 1.42e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 3 LKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAEG 78
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKtggtVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 HIDF--KTGERVTIVGKPE--QETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNED-TLFCEVCNDATLGNRK 153
Cdd:pfam00224 81 KKDIelKAGDEMIVSTDAKykGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 154 SVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVA 233
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 234 DGVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 313
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|
gi 1199513147 314 GKYPVEAVKTMAKIAAQAEK 333
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEK 340
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
2-467 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 636.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 2 MLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAE 77
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKElgrpVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 78 GHIDFKTGERVTIVGKPEqETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNV 157
Cdd:COG0469 81 GPVELKKGDTFTLTTDDV-EGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 158 PGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADGVM 237
Cdd:COG0469 160 PGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 238 VARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 317
Cdd:COG0469 240 VARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYP 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 318 VEAVKTMAKIAAQAEKDKMEENDIPIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVLAI 397
Cdd:COG0469 320 VEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1199513147 398 CYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSG---GKKGThTSFLEINQV 467
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGvpvGVPGT-TNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-458 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 634.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 1 MMLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASA 76
Cdd:PRK05826 1 RMLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKlgrpVAILLDLKGPKIRVGKFK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 77 EGHIDFKTGERVTIVGKPEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVN 156
Cdd:PRK05826 81 EGKITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 157 VPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQS-DIQIIAKIENQEGVDNIDEILEVADG 235
Cdd:PRK05826 161 IPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCpHAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 236 VMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 316 YPVEAVKTMAKIAAQAEKDKmEENDIPIPLTPDNTDVTSFLAKQAVRATT-LMPIRAIITDSFSGRTARNLAAFRGKYPV 394
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKEF-SINLSKHRLDRQFDRIDEAIAMSAMYAANhLKGVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1199513147 395 LAICYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSGGKKGTH 458
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTA 463
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
4-464 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 514.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 4 KQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVS----NRIGILMDTKGPEVRTTASAEGH 79
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAeklgRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 80 IDFKTGERVTIVGKP-EQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNVP 158
Cdd:TIGR01064 81 VKLKKGDKVIITTDDiKGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 159 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAH-QSDIQIIAKIENQEGVDNIDEILEVADGVM 237
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 238 VARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 317
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 318 VEAVKTMAKIAAQAEK--DKMEENDIPIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVL 395
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKalAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1199513147 396 AICYKEKTMRHLALSYGVEAIYMPEKAN-GQEYYFTALRKLLSDGVLTPKEMVAYLSGGKKGT--HTSFLEI 464
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGegGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
3-464 |
1.11e-161 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 466.41 E-value: 1.11e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 3 LKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAEG 78
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKtggpVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 H-IDFKTGERVTIVGKP-EQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNED-TLFCEVCNDATLGNRKSV 155
Cdd:cd00288 81 KdISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 156 NVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADG 235
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 236 VMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 316 YPVEAVKTMAKIAAQAEKdKMEENDI---PIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKY 392
Cdd:cd00288 321 YPVEAVKAMARICLEAEK-ALSHRVLfneMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1199513147 393 PVLAICYKEKTMRHLALSYGVEAIYMPEK----ANGQEYYFT-ALRKLLSDGVLTPKEMVAYLSGGKKGT-HTSFLEI 464
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwQEDTDARLKaAVNVAKEKGLLKKGDLVVVVQGWPVGSgSTNTMRI 477
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-471 |
6.28e-158 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 460.93 E-value: 6.28e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 1 MMLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASA 76
Cdd:PRK06354 5 DLMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKlgktVGILQDLQGPKIRLGRFE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 77 EGHIDFKTGERVTIVGKpEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRV--IDKNEDTLFCEVCNDATLGNRKS 154
Cdd:PRK06354 85 DGPIELKTGDEFILTSR-EVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVeeVDKADGELHCKVLVGGVLSNKKG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 155 VNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQ-SDIQIIAKIENQEGVDNIDEILEVA 233
Cdd:PRK06354 164 VNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNgKHIPIIAKIEKQEAIDNIDAILELC 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 234 DGVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 313
Cdd:PRK06354 244 DGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 314 GKYPVEAVKTMAKIAAQAEKDkMEENDIPIPLTPDNTDVTSFLAkQAVRATTL-MPIRAIITDSFSGRTARNLAAFRGKY 392
Cdd:PRK06354 324 GDYPVEAVQTMATIAVRIEKD-LPYRDILSKRPEFTTTITNAIS-QAVSHIALqLDAAAIVTLTKSGATARNVSKYRPKT 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 393 PVLAICYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSG---GKKGThTSFLEINQVDD 469
Cdd:PRK06354 402 PILAVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGtlvGESGS-TDLMKVHVVGA 480
|
..
gi 1199513147 470 VL 471
Cdd:PRK06354 481 VV 482
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
3-452 |
3.51e-147 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 429.09 E-value: 3.51e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 3 LKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSN----RIGILMDTKGPEVRTTASAEG 78
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSktgkKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 H-IDFKTGERVTIVGKPEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNV 157
Cdd:PRK09206 81 NdVSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 158 PGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQ-SDIQIIAKIENQEGVDNIDEILEVADGV 236
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGgENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 237 MVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 317 PVEAVKTMAKIAAQAekDKMEENDIPIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVLA 396
Cdd:PRK09206 321 PLEAVSIMATICERT--DRVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILA 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1199513147 397 ICYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSG 452
Cdd:PRK09206 399 LTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSG 454
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
3-333 |
1.42e-136 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 397.51 E-value: 1.42e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 3 LKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAEG 78
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKtggtVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 HIDF--KTGERVTIVGKPE--QETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNED-TLFCEVCNDATLGNRK 153
Cdd:pfam00224 81 KKDIelKAGDEMIVSTDAKykGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 154 SVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVA 233
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 234 DGVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 313
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|
gi 1199513147 314 GKYPVEAVKTMAKIAAQAEK 333
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEK 340
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-467 |
3.23e-134 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 396.22 E-value: 3.23e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 1 MMLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASA 76
Cdd:PRK06247 2 KRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDEtgrpIGILADLQGPKLRLGRFA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 77 EGHIDFKTGERVTIVGKPEqETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVN 156
Cdd:PRK06247 82 DGKVQLANGQTFRLDVDDA-PGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 157 VPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILdahQSDIQIIAKIENQEGVDNIDEILEVADGV 236
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKII---GGRVPVMAKIEKPQAIDRLEAIVEASDAI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 237 MVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:PRK06247 238 MVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 317 PVEAVKTMAKIAAQAEKDKMEENDIPIPLT-PDNT--DVTSFLAKQAvrATTLmPIRAIITDSFSGRTARNLAAFRGKYP 393
Cdd:PRK06247 318 PVEAVRTMARIIRQVERDPTYPPLIHAQRPqPEATkrDAISYAARDI--AERL-DLAALVAYTSSGDTALRAARERPPLP 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1199513147 394 VLAICYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSG---GKKGThTSFLEINQV 467
Cdd:PRK06247 395 ILALTPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGvppGTPGS-TNMLRIAYI 470
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
4-415 |
1.00e-127 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 380.86 E-value: 1.00e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 4 KQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGF-ETLiNNVRQVSNRIGI----LMDTKGPEVRTTASAEG 78
Cdd:PLN02461 21 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHqETL-DNLRQAMANTGIlcavMLDTKGPEIRTGFLKDG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 H-IDFKTGERVTIVGKPEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVI--DKNEDTLFCEVCNDATLGNRKSV 155
Cdd:PLN02461 100 KpVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLscDVEAGTVRCRCENSAMLGERKNV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 156 NVPGVRINLPSLTEKDRNNIL-YAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVAD 234
Cdd:PLN02461 180 NLPGVVVDLPTLTEKDKEDILqWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESD 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 235 GVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYG 314
Cdd:PLN02461 260 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 315 KYPVEAVKTMAKIAAQAE---------KDKMEEndIPIPLTPDNTdvtsfLAKQAVRATTLMPIRAIITDSFSGRTARNL 385
Cdd:PLN02461 340 AYPELAVKTMARICREAEasldygalfKEIMRS--APLPMSPLES-----LASSAVRTANKVKASLIVVLTRGGTTARLV 412
|
410 420 430
....*....|....*....|....*....|
gi 1199513147 386 AAFRGKYPVLAICYKEKTMRHLALSYGVEA 415
Cdd:PLN02461 413 AKYRPAVPILSVVVPEITTDSFDWSCSDEA 442
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
4-419 |
2.50e-118 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 356.76 E-value: 2.50e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 4 KQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQV-----SNRIGILMDTKGPEVRTtASAEG 78
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAakarpNANLGILLDTKGPEIRT-GFLKN 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 H--IDFKTGERVTIVGKPEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVN 156
Cdd:PTZ00066 117 HkpITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMN 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 157 VPGVRINLPSLTEKDRNNIL-YAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADG 235
Cdd:PTZ00066 197 LPGVKVELPVIGEKDKNDILnFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDG 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 236 VMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:PTZ00066 277 IMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGK 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 316 YPVEAVKTMAKIAAQAE-----KDKMEE--NDIPIPLTpdntdVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAF 388
Cdd:PTZ00066 357 FPVEAVNIMAKICFEAEtcidyRVLYHAihLAVPTPVS-----VQEAVARSAVETAEDINAKLIIALTETGNTARLISKY 431
|
410 420 430
....*....|....*....|....*....|.
gi 1199513147 389 RGKYPVLAICYKEKTMRHLALSYGVEAIYMP 419
Cdd:PTZ00066 432 RPSCTILALSASPSVVKSLSVARGVTTYVVN 462
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
30-426 |
1.28e-109 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 332.40 E-value: 1.28e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 30 MNVVRMNTAHASREGFETLINNVRQVSNR----IGILMDTKGPEVRTTASAEGHIDFKTGERVTIVGKP--EQETTHECI 103
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAElgvnIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPafADKGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 104 AVSYPGFVNDLSVGVDVLIDDGDLELRVIDK-NEDTLFCEVCNDATLGNRKSVNVPGVRINLPSLTEKDRNNILYAIEKD 182
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVQSHeDEQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 183 IDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRKLIKK 262
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 263 CILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMAKIAAQAEKDKMEE---N 339
Cdd:PTZ00300 241 CNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYvffN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 340 DI----PIPLTPDNTDVTSflakqAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGVEA 415
Cdd:PTZ00300 321 SIkklqPIPMSAEEAVCSS-----AVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVES 395
|
410
....*....|.
gi 1199513147 416 IYMPEKANGQE 426
Cdd:PTZ00300 396 VFFDAERLGHD 406
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
4-455 |
9.41e-100 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 311.09 E-value: 9.41e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 4 KQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQ-----VSNRIGILMDTKGPEVRTTASAEG 78
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEynaqsKDNVIAIMLDTKGPEVRSGDLPQP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 79 hIDFKTGERVTIVGKpEQETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNVP 158
Cdd:PLN02623 190 -IMLEEGQEFTFTIK-RGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVR 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 159 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQIIAKIENQEGVDNIDEILEVADGVMV 238
Cdd:PLN02623 268 GKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASDGAMV 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 239 ARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPV 318
Cdd:PLN02623 348 ARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPL 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 319 EAVKTMAKIAAQAEKDKMEENDIPIPLTPDNTDVTSFLAKQA-VRATTLMPirAIITDSFSGRTARNLAAFRGKYPVLAI 397
Cdd:PLN02623 428 KAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMSEMFAFHAtMMANTLGT--SIIVFTRTGFMAILLSHYRPSGTIFAF 505
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1199513147 398 CYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKLLSDGVLTPKEMVAYLSGGKK 455
Cdd:PLN02623 506 TNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEEVALVQSGRQ 563
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
20-332 |
4.98e-84 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 263.34 E-value: 4.98e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 20 DFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNRIGILMDTKGPEVRTTASAEGHIDFKTGERVTIVGKPEQETT 99
Cdd:PRK06739 17 ETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILGDVQGPKIRLGEIKGEQITLQAGDSFILHTQPVTGSS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 100 HECiAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNRKSVNVPGVRINLPSLTEKDRNNILYAI 179
Cdd:PRK06739 97 TEA-SVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLPAITEKDKKDIQFLL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 180 EKDIDFIAHSFVRNKQDVLDIRE-ILDAHQSDIQIIAKIENQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRK 258
Cdd:PRK06739 176 EEDVDFIACSFVRKPSHIKEIRDfIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDLGVELPYQFIPLLQKM 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1199513147 259 LIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMAKIAAQAE 332
Cdd:PRK06739 256 MIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTLRLVSEFAE 329
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
6-403 |
1.38e-83 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 267.69 E-value: 1.38e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 6 TKIVASISDLRCDVDFIRDLFNAGMNVVRMN----TAHASREGFETLINNVRQVSNRIGILMDTKGPEVRTTASAEGHID 81
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDfswgDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPIS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 82 FKTGERVTIVGKPEQETTHECIAVSYPGFVNDLSVGVDVLI--------DDGDLELRVIDKNEDTLFCEVCNDATL-GNR 152
Cdd:PLN02765 110 LKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKNSATLaGSL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 153 KSVNVPGVRINLPSLTEKDRNNI-LYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQ-SDIQIIAKIENQEGVDNIDEIL 230
Cdd:PLN02765 190 FTLHVSQVRIDLPTLSEKDKEVIsTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIENVEGLTHFDEIL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 231 EVADGVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVaTQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGE 310
Cdd:PLN02765 270 QEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILLGAE 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 311 TAYGKYPVEAVKTMAKIAAQAEKDKMEENDIP--IPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAF 388
Cdd:PLN02765 349 TLRGLYPVETISTVGRICAEAEKVFNQDLYFKktVKYVGEPMSHLESIASSAVRAAIKVKASVIIVFTSSGRAARLIAKY 428
|
410
....*....|....*.
gi 1199513147 389 RGKYPVLA-ICYKEKT 403
Cdd:PLN02765 429 RPTMPVLSvVIPRLKT 444
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
1-413 |
3.87e-73 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 239.65 E-value: 3.87e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 1 MMLKQTKIVASISDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNRIG----ILMDTKGPEVR----- 71
Cdd:PLN02762 22 RSTRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGfavaVMMDTEGSEIHmgdlg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 72 --TTASAEghidfkTGERVTIVGKPEQETTHEC-IAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEvCNDAT 148
Cdd:PLN02762 102 gaSSAKAE------DGEEWTFTVRKFDGSRPEFtIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCK-CTDPG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 149 L----GN----RKSVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNKQDVLDIREILDAH--QSDIQIIAKIE 218
Cdd:PLN02762 175 LllprANltfwRDGSLVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARsrDSDIGVIAKIE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 219 NQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAI 298
Cdd:PLN02762 255 SLDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAV 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 299 YYRTDALMLSGETAYGKYPVEAVKTMAKIAAQAEKDKMEEN---DIPIP-LTPDNTDVTS-FLAKQAVRATTLMPIRAII 373
Cdd:PLN02762 335 RQRADALMLSGESAMGLYPEKALSVLRSVSLRMELWSREEKrheALELPqLSSSLSDRISeEICNSAAKMANNLGVDAIF 414
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1199513147 374 TDSFSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGV 413
Cdd:PLN02762 415 VYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGL 454
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
13-335 |
2.41e-58 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 200.24 E-value: 2.41e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 13 SDLRCDVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNRIG----ILMDTKGPEVRTTASAE--GHIDFKTGE 86
Cdd:PRK08187 143 SEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGrrckILMDLAGPKIRTGAVAGplGKTRLYTGD 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 87 RVTIVGKPE---QETTHECIAVSYPGFVNDLSVGVDVLIDDGDLELRVIDKNEDTLFCEVCNDATLGNR----KSVNVPG 159
Cdd:PRK08187 223 RLALVAQGPprrIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTHARPKGLKlkpeKGLNFPD 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 160 VRINLPSLTEKDRnnilyaieKDIDFIA-------HSFVRNKQDVLDIREILDAHQSD----IQIIAKIENQEGVDNIDE 228
Cdd:PRK08187 303 TALDLPALTEKDR--------ADLDFVArhadlvgYSFVQSPGDVEALQAALAARRPDdwrkLGLVLKIETPRAVANLPE 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 229 ILEVADG-----VMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAiyYRTD 303
Cdd:PRK08187 375 LIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA--ARAE 452
|
330 340 350
....*....|....*....|....*....|....
gi 1199513147 304 ALMLSGetayGKYPVEAVKTMAKIAA--QAEKDK 335
Cdd:PRK08187 453 CVMLNK----GPYLVEAVTFLDDLLArmDGHQHK 482
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
18-327 |
2.04e-43 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 162.04 E-value: 2.04e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 18 DVDFIRDLFNAGMNVVRMNTAHASREGFETLINNVRQVSNRIG----ILMDTKGPEVRT--------------------- 72
Cdd:PRK14725 154 DPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGrrcrIAMDLAGPKLRTgpiapgprviklrptrdalgr 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 73 ---------------TASA------------------------------------------------------------- 76
Cdd:PRK14725 234 vltparlwltasespPPSPppgpvglpvdpewlarlepgdelrftdargkkrkltvtevddegvlaegsqtaylangtll 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 77 ----------------EGHIDFKTGERVTIV--GKPEQETTHEC----IAVSYPGFVNDLSVGVDVLIDDGDLELRVIDK 134
Cdd:PRK14725 314 rlgrhdstrvgglppvEQKLRLKVGDRLVLTrdDAPGDPAQGDApparISCTLPEAFRAARVGERVWFDDGKIGAVVVKV 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 135 NEDTLFCEVCND----ATLGNRKSVNVPGVRINLPSLTEKDRNNiLYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQ-S 209
Cdd:PRK14725 394 EADEVELRITHArpggSKLKAGKGINLPDSHLPLPALTDKDLED-LAFVAKHADIVALSFVRSPEDVRLLLDALEKLGaD 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 210 DIQIIAKIENQEGVDNIDEILEVA-----DGVMVARGDLGIEVPQERIPGIQRKLIKKCILARKPVIVATQMLHTMINNP 284
Cdd:PRK14725 473 DLGVVLKIETRRAFENLPRILLEAmrhprFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKG 552
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1199513147 285 RPTRAEVTDIANAIyyRTDALMLSGetayGKYPVEAVKTMAKI 327
Cdd:PRK14725 553 LPSRAEITDAAMAL--RAECVMLNK----GPHIVEAVRVLDDI 589
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
262-423 |
3.03e-38 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 141.96 E-value: 3.03e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 262 KCILARKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMAKIAAQAEKDKMEENDI 341
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 342 PIPLTPDNTDVTSFLAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGVEAIYMPEK 421
Cdd:COG3848 81 VPRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEES 160
|
..
gi 1199513147 422 AN 423
Cdd:COG3848 161 AS 162
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
356-464 |
4.04e-15 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 71.36 E-value: 4.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 356 LAKQAVRATTLMPIRAIITDSFSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGVEAIYMPEKANGQEYYFTALRKL 435
Cdd:pfam02887 3 IAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKVA 82
|
90 100 110
....*....|....*....|....*....|..
gi 1199513147 436 LSDGVLTPKEMVAYLSG---GKKGThTSFLEI 464
Cdd:pfam02887 83 KEAGLVKKGDLVVITAGvpfGVSGT-TNTLKV 113
|
|
| PRK10558 |
PRK10558 |
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional |
210-243 |
2.04e-03 |
|
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional
Pssm-ID: 182547 Cd Length: 256 Bit Score: 40.11 E-value: 2.04e-03
10 20 30
....*....|....*....|....*....|....*.
gi 1199513147 210 DIQIIAKIENQEGVDNIDEI--LEVADGVMVARGDL 243
Cdd:PRK10558 145 NITVLVQIESQQGVDNVDAIaaTEGVDGIFVGPSDL 180
|
|
| HpcH_HpaI |
pfam03328 |
HpcH/HpaI aldolase/citrate lyase family; This family includes 2,4-dihydroxyhept-2-ene-1, ... |
158-294 |
6.85e-03 |
|
HpcH/HpaI aldolase/citrate lyase family; This family includes 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase and 4-hydroxy-2-oxovalerate aldolase.
Pssm-ID: 427247 [Multi-domain] Cd Length: 221 Bit Score: 38.10 E-value: 6.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199513147 158 PGVRINL--PSLTEKDrnniLYAIEKDIDFIAHSFVRNKQDVLDIREILDAHQSDIQ-------IIAKIENQEGVDNIDE 228
Cdd:pfam03328 62 VVVRVNSldSPFGKQD----LAVLDLGAQVVLVPKVETAEDARAAVSAIRYPPKGIRrangntcLLAQIESALGVLNADE 137
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1199513147 229 ILEV--ADGVMVARGDLGIEVPQERIPGIQ--RKLIKKCILA-RKPVIVATQMLHTMINNPRPTRAEVTDI 294
Cdd:pfam03328 138 IAAVegVDGIFLGAEDLSADLGTLRSPGGPevLYARERIVTAaRAAGIAAFDTVYSDENDAEGFLAEGALF 208
|
|
| |
