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Conserved domains on  [gi|1199694907|ref|WP_087425760|]
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UpxZ family transcription anti-terminator antagonist [Bacteroides clarus]

Protein Classification

UpxZ family transcription anti-terminator antagonist( domain architecture ID 10535094)

UpxZ family transcription anti-terminator antagonist inhibits the synthesis of heterologous polysaccharides by interfering with the ability of UpxY proteins, encoded by other polysaccharide loci, to function in transcriptional antitermination of their respective operons

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UpxZ pfam06603
UpxZ family of transcription anti-terminator antagonists; The UpxZ family of proteins acts to ...
 2-104 3.10e-48

UpxZ family of transcription anti-terminator antagonists; The UpxZ family of proteins acts to inhibit transcription of heterologous capsular polysaccharide loci in Bacteroides species by interfering with the action of the UpxY family of transcription anti-terminators. As antagonists of polysaccharide locus-specific UpxY transcription anti-terminators, the UpxZ proteins exert a hierarchical level of regulation, insuring that only one of the multiple phase-variable capsular polysaccharide loci per cell characteriztic of this genus is transcribed at a time.


:

Pssm-ID: 429027  Cd Length: 104  Bit Score: 150.94  E-value: 3.10e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199694907   2 DSLFSLAHRLLTYGLDGSPIYVDEFTRLNREVYEQALELYGTRGKTVESEAELCLGLLAAFAATIYDNGHKQQYIQQVLD 81
Cdd:pfam06603   1 ESLQSVAHELLYLGEDGSPIYSDDLSRLNKEVLELSNDLYSQKGETPEEEANLCLALLMGYNATIYNNGEKEEKIQEVLD 80

                          90       100
                  ....*....|....*....|...
gi 1199694907  82 RSWEVLPKLPASLLKVQLLVYCY 104
Cdd:pfam06603  81 RSWDVLDTLPASLLKCQLLTYCY 103
 
Name Accession Description Interval E-value
UpxZ pfam06603
UpxZ family of transcription anti-terminator antagonists; The UpxZ family of proteins acts to ...
 2-104 3.10e-48

UpxZ family of transcription anti-terminator antagonists; The UpxZ family of proteins acts to inhibit transcription of heterologous capsular polysaccharide loci in Bacteroides species by interfering with the action of the UpxY family of transcription anti-terminators. As antagonists of polysaccharide locus-specific UpxY transcription anti-terminators, the UpxZ proteins exert a hierarchical level of regulation, insuring that only one of the multiple phase-variable capsular polysaccharide loci per cell characteriztic of this genus is transcribed at a time.


Pssm-ID: 429027  Cd Length: 104  Bit Score: 150.94  E-value: 3.10e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199694907   2 DSLFSLAHRLLTYGLDGSPIYVDEFTRLNREVYEQALELYGTRGKTVESEAELCLGLLAAFAATIYDNGHKQQYIQQVLD 81
Cdd:pfam06603   1 ESLQSVAHELLYLGEDGSPIYSDDLSRLNKEVLELSNDLYSQKGETPEEEANLCLALLMGYNATIYNNGEKEEKIQEVLD 80

                          90       100
                  ....*....|....*....|...
gi 1199694907  82 RSWEVLPKLPASLLKVQLLVYCY 104
Cdd:pfam06603  81 RSWDVLDTLPASLLKCQLLTYCY 103
 
Name Accession Description Interval E-value
UpxZ pfam06603
UpxZ family of transcription anti-terminator antagonists; The UpxZ family of proteins acts to ...
 2-104 3.10e-48

UpxZ family of transcription anti-terminator antagonists; The UpxZ family of proteins acts to inhibit transcription of heterologous capsular polysaccharide loci in Bacteroides species by interfering with the action of the UpxY family of transcription anti-terminators. As antagonists of polysaccharide locus-specific UpxY transcription anti-terminators, the UpxZ proteins exert a hierarchical level of regulation, insuring that only one of the multiple phase-variable capsular polysaccharide loci per cell characteriztic of this genus is transcribed at a time.


Pssm-ID: 429027  Cd Length: 104  Bit Score: 150.94  E-value: 3.10e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199694907   2 DSLFSLAHRLLTYGLDGSPIYVDEFTRLNREVYEQALELYGTRGKTVESEAELCLGLLAAFAATIYDNGHKQQYIQQVLD 81
Cdd:pfam06603   1 ESLQSVAHELLYLGEDGSPIYSDDLSRLNKEVLELSNDLYSQKGETPEEEANLCLALLMGYNATIYNNGEKEEKIQEVLD 80

                          90       100
                  ....*....|....*....|...
gi 1199694907  82 RSWEVLPKLPASLLKVQLLVYCY 104
Cdd:pfam06603  81 RSWDVLDTLPASLLKCQLLTYCY 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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