|
Name |
Accession |
Description |
Interval |
E-value |
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
25-409 |
1.71e-167 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 475.51 E-value: 1.71e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 25 YFTVQGDAVYRR--KHQMLVGVLGGTTAMLCLSLPVKIDN-VLWDLRMIPLILAVVYGGWRAGLIAAVPALLYRAQLGGG 101
Cdd:COG5806 18 YQIFWEDRRRNKpvKNRMLIGVLSSIAIILCMTFPIHITDgFIFDLRQVPIILGTLYGGWRVGLFLFLILLLYRFYLGGE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 102 SVWLELAAGAVSLGICFVLARSFLRFAPRQRILLCMLLSFLSFLPLGL------AVNASHLDLLLVQGALHILGIGICSY 175
Cdd:COG5806 98 GVFVTLLVYTVILILPLLLRRKFHRLSRKGKIVLAILLSFLSALLLLLlaiifiADISELLDFILYFIIIQLLAMLIAVY 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 176 LIENKIQTLLLHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGS--LDEKARPAMQIALTELDRANYIISDY 253
Cdd:COG5806 178 LIENLIENILLRKELQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPelSDEKRKQYIRIALEELDRAEAIITDY 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 254 LNFAKPRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGLLVNADAGQLQQALMNLVKNGIEAIAEpSGTVTIQ 333
Cdd:COG5806 258 LTFAKPQPEKLEKIDVSEELEHVIDVLSPYANMNNVEIQTELEPGLYIEGDRQKLQQCLINIIKNGIEAMPN-GGTLTID 336
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1199727195 334 AFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAV 409
Cdd:COG5806 337 VSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITLPLA 412
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
188-409 |
3.48e-69 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 226.92 E-value: 3.48e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 188 RELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGSLDEKaRPAMQIALTELDRANYIISDYLNFAKPRPESIQVF 267
Cdd:COG5805 276 ELMARSEKLSIAGQLAAGIAHEIRNPLTSIKGFLQLLQPGIEDK-EEYFDIMLSELDRIESIISEFLALAKPQAVNKEKE 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 268 DVADVVRHIAMVMGAFGTLRGVEIRTDCSEGLL-VNADAGQLQQALMNLVKNGIEAIaePS-GTVTIQAFLQGETVLLSV 345
Cdd:COG5805 355 NINELIQDVVTLLETEAILHNIQIRLELLDEDPfIYCDENQIKQVFINLIKNAIEAM--PNgGTITIHTEEEDNSVIIRV 432
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1199727195 346 RDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAV 409
Cdd:COG5805 433 IDEGIGIPEERLKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPLS 496
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
182-408 |
4.98e-68 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 219.72 E-value: 4.98e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 182 QTLLLHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGSL-DEKARPAMQIALTELDRANYIISDYLNFAKPR 260
Cdd:COG3852 118 ERKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELpDDELREYTQLIIEEADRLNNLVDRLLSFSRPR 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 261 PESIQVFDVADVVRHIAMVMGAfGTLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEAIAEPsGTVTIQAFLQ-- 337
Cdd:COG3852 198 PPEREPVNLHEVLERVLELLRA-EAPKNIRIVRDYDPSLpEVLGDPDQLIQVLLNLVRNAAEAMPEG-GTITIRTRVErq 275
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1199727195 338 --------GETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPA 408
Cdd:COG3852 276 vtlgglrpRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPL 354
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
170-407 |
9.53e-67 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 216.58 E-value: 9.53e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 170 IGICSYLIENKiqtlLLHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLAL-GSLDEKARPAMQIALTELDRANY 248
Cdd:COG5807 122 ITVYRDITKRK----EAEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQeSREDSEREEYFNIIISEIDRINT 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 249 IISDYLNFAKPRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEAIAEpS 327
Cdd:COG5807 198 IITELLVLSKPKKFNFKKLNLNDVLEDVIALLSTEAILKNISIKYDLADDEpVINGDKNQLKQVFINLIKNAIEAMET-G 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 328 GTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:COG5807 277 GNITIKTYVEGDFVVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLSICKKIIEEHNGTIEVESKPGKGTTFTIYLP 356
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
177-400 |
1.05e-65 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 217.53 E-value: 1.05e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 177 IENKIQTLLLhreLANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGSLDEKARPAMQIALTELDRANYIISDYLNF 256
Cdd:COG5809 251 ITERKKLEEL---LRKSEKLSVVGELAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQKTYLDIMLSELDRIESIISEFLVL 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 257 AKPRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEAIAEPsGTVTIQAF 335
Cdd:COG5809 328 AKPQAIKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIpDILGDENQLKQVFINLLKNAIEAMPEG-GNITIETK 406
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1199727195 336 LQGET-VLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGT 400
Cdd:COG5809 407 AEDDDkVVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGT 472
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
66-409 |
9.22e-62 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 203.49 E-value: 9.22e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 66 DLRMIPLILAVVYGGWRAGLIAAVPALLYRAQLGGGSVWLELAAGAVSLGICFVLARSFLRFAPRQRILLCMLLSFLSFL 145
Cdd:COG4191 1 ALRLLLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 146 PLGLAVNASHLDLLLVQGALHILGIGICSYLIENKIQTLL--------LHRELANKERLNIISELAAVIAHEVKNPLTVV 217
Cdd:COG4191 81 LLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELEraeeelreLQEQLVQSEKLAALGELAAGIAHEINNPLAAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 218 RGFLQLALGSLD-----EKARPAMQIALTELDRANYIISDYLNFAKPRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIR 292
Cdd:COG4191 161 LGNAELLRRRLEdepdpEELREALERILEGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELLRPRLKARGIEVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 293 TDCSEGL-LVNADAGQLQQALMNLVKNGIEAIAE-PSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTK-- 368
Cdd:COG4191 241 LDLPPDLpPVLGDPGQLEQVLLNLLINAIDAMEEgEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFTTKpv 320
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1199727195 369 TSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAV 409
Cdd:COG4191 321 GKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLPLA 361
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
160-409 |
2.05e-61 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 204.43 E-value: 2.05e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 160 LVQGALHILGIGICSYLIENKIQTLLLHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQL-------ALGSLDEKA 232
Cdd:COG5000 162 LTRDGRRTLLVRASPLRDDGYVIVFDDITELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERlrrkladKLEEDREDL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 233 RPAMQIALTELDRANYIISDYLNFAKPRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGLL-VNADAGQLQQA 311
Cdd:COG5000 242 ERALDTIIRQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPeVLADRDQLEQV 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 312 LMNLVKNGIEAIaEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLT 391
Cdd:COG5000 322 LINLLKNAIEAI-EEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTIE 400
|
250
....*....|....*...
gi 1199727195 392 FHSAPGLGTEAVVKIPAV 409
Cdd:COG5000 401 LESRPGGGTTFTIRLPLA 418
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
91-408 |
1.59e-54 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 183.57 E-value: 1.59e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 91 ALLYRAQLGGGSVWLELAAGAVSLGICFVLARSFLRFAPRQRILLCMLLSFLSFLPLGLAVNASHLDLLLVQGALHILGI 170
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 171 GICSYLIENKIQTLLLHRELANKERLN-IISELAAVIAHEVKNPLTVVRGFLQLALGSLDEKARPAMQIALTELDRANYI 249
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANeAKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQREYLETILRSADRLLRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 250 ISDYLNFAK----PRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGLL-VNADAGQLQQALMNLVKNGIEAiA 324
Cdd:COG0642 161 INDLLDLSRleagKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPtVRGDPDRLRQVLLNLLSNAIKY-T 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 325 EPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTS----GTGLGTMVTRKIIEGMKGTLTFHSAPGLGT 400
Cdd:COG0642 240 PEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSrrggGTGLGLAIVKRIVELHGGTIEVESEPGKGT 319
|
....*...
gi 1199727195 401 EAVVKIPA 408
Cdd:COG0642 320 TFTVTLPL 327
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
186-408 |
4.40e-48 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 163.92 E-value: 4.40e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 186 LHRELANKERLN-IISELAAVIAHEVKNPLTVVRGFLQLAL---GSLDEKARPAMQIALTELDRANYIISDYLNFAKPRP 261
Cdd:COG2205 2 LEEALEELEELErLKSEFLANVSHELRTPLTSILGAAELLLdeeDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 262 ESIQV----FDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGLL-VNADAGQLQQALMNLVKNGIEAiAEPSGTVTIQAFL 336
Cdd:COG2205 82 GKLSLelepVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPlVYADPELLEQVLANLLDNAIKY-SPPGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1199727195 337 QGETVLLSVRDTGVGMSAEQLRRMGTPFY----TTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPA 408
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPL 236
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
151-409 |
1.06e-47 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 169.16 E-value: 1.06e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 151 VNASHLDLLLVQGALHILGIGICSYLIENKIQTLLLHRELA--------NKERLNIISELAAVIAHEVKNPLTVVRGFLQ 222
Cdd:COG5808 185 PNPVTNDELGQALAIRKLIILVLISIIFLLLQYNLLKRKTLlerviqeiNTQKLELIGTFAASTAHEIRNPLTSIKGFIQ 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 223 L-ALGSLDEKARPAMQIALTELDRANYIISDYLNFAKPRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEG-LL 300
Cdd:COG5808 265 LlQEKYPELEDQKYFDIIQEEIQRINQIVSEFLVLGKPTAKKLELDDLNELIEEILSIIDSEANLKNIRVEKQSLDEpLH 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 301 VNADAGQLQQALMNLVKNGIEAIAEpSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTR 380
Cdd:COG5808 345 IKCDKDRIKQVLLNLIKNAIEAMKE-GGKLTISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCK 423
|
250 260
....*....|....*....|....*....
gi 1199727195 381 KIIEGMKGTLTFHSAPGLGTEAVVKIPAV 409
Cdd:COG5808 424 RIVEMHGGEIDIESEEGKGTTFTIRLPLK 452
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
63-409 |
2.15e-43 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 155.87 E-value: 2.15e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 63 VLWDLRMIPLILAVVYGGWRAGLIAAVPALLYRAQLGGGSVWLELAAGAVSLGICFVLARSFLRFAPRQRILLCMLLSFL 142
Cdd:COG5002 28 LLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 143 SFLPLGLAVNASHLDLLLVQGALHILGIGICSYLIENKIQTLLLHRELANKERLN-IISELAAVIAHEVKNPLTVVRGFL 221
Cdd:COG5002 108 LALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEqMRREFVANVSHELRTPLTSIRGYL 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 222 QLALG---SLDEKARPAMQIALTELDRANYIISDYLNFAK----PRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTD 294
Cdd:COG5002 188 ELLLDgaaDDPEERREYLEIILEEAERLSRLVNDLLDLSRlesgELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELD 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 295 CSEGLL-VNADAGQLQQALMNLVKNGIEAiAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTT------ 367
Cdd:COG5002 268 LPEDPLlVLGDPDRLEQVLTNLLDNAIKY-TPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVdksrsr 346
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1199727195 368 KTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAV 409
Cdd:COG5002 347 ETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPLA 388
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
186-407 |
2.51e-42 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 157.05 E-value: 2.51e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 186 LHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGSLDEKARP-AMQIALTELDRANYIISDYLNFAKPRPESI 264
Cdd:PRK11360 377 LQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQeYLSVVLREVDRLNKVIDQLLEFSRPRESQW 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 265 QVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEAIAEpSGTVTIQAFLQGET-VL 342
Cdd:PRK11360 457 QPVSLNALVEEVLQLFQTAGVQARVDFETELDNELpPIWADPELLKQVLLNILINAVQAISA-RGKIRIRTWQYSDGqVA 535
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1199727195 343 LSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:PRK11360 536 VSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
185-407 |
6.38e-41 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 150.71 E-value: 6.38e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 185 LLHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGSLDE--KARPAMQIALTELDRANYIISDYLNFAKPRPE 262
Cdd:PRK10364 223 LLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAggEAHQLAQVMAKEADRLNRVVSELLELVKPTHL 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 263 SIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEAIAEpSGTVTIQAFLQGETV 341
Cdd:PRK10364 303 ALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLpEIQADPDRLTQVLLNLYLNAIQAIGQ-HGVISVTASESGAGV 381
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1199727195 342 LLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:PRK10364 382 KISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
172-407 |
2.82e-34 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 135.19 E-value: 2.82e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 172 ICSYLIENKIQT--LLLHRELANKERLNIISELAAVIAHEVKNPLTVVRGFLQLALGSLDEKARPAMQIALT--ELDRAN 247
Cdd:PRK13837 421 LAHAIERRRLETerDALERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIisAGARAR 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 248 YIISDYLNFAKPRPESIQVFDVADVVRHIAMVMGAfGTLRGVEIRTD-CSEGLLVNADAGQLQQALMNLVKNGIEAIaEP 326
Cdd:PRK13837 501 LIIDQILAFGRKGERNTKPFDLSELVTEIAPLLRV-SLPPGVELDFDqDQEPAVVEGNPAELQQVLMNLCSNAAQAM-DG 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 327 SGTVTIQAFLQ---------------GETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLT 391
Cdd:PRK13837 579 AGRVDISLSRAklrapkvlshgvlppGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYID 658
|
250
....*....|....*.
gi 1199727195 392 FHSAPGLGTEAVVKIP 407
Cdd:PRK13837 659 VQSTVGRGTRFDVYLP 674
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
2-408 |
3.28e-27 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 113.34 E-value: 3.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 2 ELAELEIRNLLLHLLIVLLPVLLYFTVQGDAVYRRKHQMLVGVLGGTTAMLCLSLPVKIDNVLWDLRMIPLILAVVYGGW 81
Cdd:COG4251 75 LAALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLL 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 82 RAGLIAAVPALLYRAQLGGGSVWLELAAGAVSLGICFVLARSFLRFAPRQRILLCMLLSFLSFLPLGLAVNASHLDLLLV 161
Cdd:COG4251 155 LLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLL 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 162 QGALHILGIGICSYLIENKIQTLLLHRELANKERLNIISEL----------AAVIAHEVKNPLTVVRGFLQLAL----GS 227
Cdd:COG4251 235 LVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELersneeleqfAYVASHDLREPLRKISGFSQLLEedygDK 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 228 LDEKARPAMQIALTELDRANYIISDYLNFAK--PRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDcsEGLLVNADA 305
Cdd:COG4251 315 LDEEGREYLERIRDAAERMQALIDDLLAYSRvgRQELEFEPVDLNELLEEVLEDLEPRIEERGAEIEVG--PLPTVRGDP 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 306 GQLQQALMNLVKNGIE-AIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKT----SGTGLGTMVTR 380
Cdd:COG4251 393 TLLRQVFQNLISNAIKySRPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSrdeyEGTGIGLAIVK 472
|
410 420
....*....|....*....|....*...
gi 1199727195 381 KIIEGMKGTLTFHSAPGLGTEAVVKIPA 408
Cdd:COG4251 473 KIVERHGGRIWVESEPGEGATFYFTLPK 500
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
303-407 |
3.57e-27 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 104.27 E-value: 3.57e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 303 ADAGQLQQALMNLVKNGIEAiAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTK-----TSGTGLGTM 377
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKY-TPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDkrsrkIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|
gi 1199727195 378 VTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
303-407 |
2.94e-23 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 93.59 E-value: 2.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 303 ADAGQLQQALMNLVKNGIEAIAEPS-GTVTIQaflQGETVLLSVRDTGVGMSAEQLRRMGTPFYT---TKTSGTGLGTMV 378
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGeITVTLS---EGGELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLSI 77
|
90 100
....*....|....*....|....*....
gi 1199727195 379 TRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:pfam02518 78 VRKLVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
307-407 |
1.37e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 91.71 E-value: 1.37e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 307 QLQQALMNLVKNGIEAIAEpSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKT--SGTGLGTMVTRKIIE 384
Cdd:cd16943 3 QLNQVLLNLLVNAAQAMEG-RGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPvgEGTGLGLSLSYRIIQ 81
|
90 100
....*....|....*....|...
gi 1199727195 385 GMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16943 82 KHGGTIRVASVPGGGTRFTIILP 104
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
308-407 |
2.27e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 85.62 E-value: 2.27e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAEpsGTVTIQAFLQGET-----VLLSVRDTGVGMSAEQLRRMGTPF------YTTKTSGTGLGT 376
Cdd:cd16922 1 LRQILLNLLGNAIKFTEE--GEVTLRVSLEEEEedgvqLRFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLGL 78
|
90 100 110
....*....|....*....|....*....|.
gi 1199727195 377 MVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16922 79 AISKKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
3.06e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 82.44 E-value: 3.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAEP---SGTVTIQAFLQGE-TVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKII 383
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGgceRRELTIRTSPADDrAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|....
gi 1199727195 384 EGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16920 81 EAHGGRLSVESPAGGGATFQFTLP 104
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
172-414 |
4.87e-18 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 86.71 E-value: 4.87e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 172 ICSYLIENKIQTLLLHRELANKERLNII---SELAAVIAHEVKNPLTVVRGFLQLALGS-LDEKAR-PAMQIALTELDRA 246
Cdd:PRK09959 682 ICGWQDITETRDLIHALEVERNKAINATvakSQFLATMSHEIRTPISSIMGFLELLSGSgLSKEQRvEAISLAYATGQSL 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 247 NYIISDYLNFAKPRPESIQV----FDVADVVRHIAMVMGAFGTLRGVEIrtDCSEGL----LVNADAGQLQQALMNLVKN 318
Cdd:PRK09959 762 LGLIGEILDVDKIESGNYQLqpqwVDIPTLVQNTCHSFGAIAASKSIAL--SCSSTFpdhyLVKIDPQAFKQVLSNLLSN 839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 319 GIEAIAEpsGTVTIQAFL-----QGETVLLSVRDTGVGMSAEQLRRMGTPFYTT----KTSGTGLGTMVTRKIIEGMKGT 389
Cdd:PRK09959 840 ALKFTTE--GAVKITTSLghiddNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTsagrQQTGSGLGLMICKELIKNMQGD 917
|
250 260
....*....|....*....|....*
gi 1199727195 390 LTFHSAPGLGTEAVVKIPAVLVKEV 414
Cdd:PRK09959 918 LSLESHPGIGTTFTITIPVEISQQV 942
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
207-408 |
1.94e-16 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 81.04 E-value: 1.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 207 AHEVKNPLTVVRGFLQLALGSL--DEKARPAMQIaLTELDRANYIISDYLNFAK----PRPESIQVFDVADVVRHIAMVM 280
Cdd:PRK11100 264 THELKSPLAAIRGAAELLQEDPppEDRARFTGNI-LTQSARLQQLIDRLLELARleqrQELEVLEPVALAALLEELVEAR 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 281 GAFGTLRGVEIRTDCsEGLLVNADAGQLQQALMNLVKNGIEaIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRM 360
Cdd:PRK11100 343 EAQAAAKGITLRLRP-DDARVLGDPFLLRQALGNLLDNAID-FSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALPRI 420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1199727195 361 GTPFYT-----TKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPA 408
Cdd:PRK11100 421 FERFYSlprpaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
201-407 |
2.07e-16 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 79.74 E-value: 2.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 201 ELAAVIAHEVKNPLTVVRGFLQLALGSL-DEKARPAMQIALTELDRANYIISDYLNFAKPRPESIQ-VFDVADVVRH-IA 277
Cdd:PRK11073 132 DLVRGLAHEIKNPLGGLRGAAQLLSKALpDPALTEYTKVIIEQADRLRNLVDRLLGPQRPGTHVTEsIHKVAERVVQlVS 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 278 MVMGAfgtlrGVEIRTDCSEGLL-VNADAGQLQQALMNLVKNGIEAIAEPSGTVTI------QAFLQGETVLLSVR---- 346
Cdd:PRK11073 212 LELPD-----NVRLIRDYDPSLPeLAHDPDQIEQVLLNIVRNALQALGPEGGTITLrtrtafQLTLHGERYRLAARidie 286
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1199727195 347 DTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGlGTEAVVKIP 407
Cdd:PRK11073 287 DNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPG-HTEFSVYLP 346
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
204-407 |
2.39e-16 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 81.17 E-value: 2.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 204 AVIAHEVKNPLTVVRGFLQLalgsLDEKARP--------AMQIALTELDRanyIISDYLNFAKPRPESIQV----FDVAD 271
Cdd:PRK10841 452 ATVSHELRTPLYGIIGNLDL----LQTKELPkgvdrlvtAMNNSSSLLLK---IISDILDFSKIESEQLKIepreFSPRE 524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 272 VVRHI-----AMVMGAFGTLRGVeIRTDCSEglLVNADAGQLQQALMNLVKNGIEAIAepSGTVTIQAFLQGETVLLSVR 346
Cdd:PRK10841 525 VINHItanylPLVVKKRLGLYCF-IEPDVPV--ALNGDPMRLQQVISNLLSNAIKFTD--TGCIVLHVRVDGDYLSFRVR 599
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1199727195 347 DTGVGMSAEQLRRMGTPFYTTKTS------GTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:PRK10841 600 DTGVGIPAKEVVRLFDPFFQVGTGvqrnfqGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
180-407 |
1.44e-15 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 77.58 E-value: 1.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 180 KIQTLLLHRELANKERLNiisELAAVIAHEVKNPLTVVRGFLQLalGSLDEkarpAMQIALTELDRANYIISDYLnfakp 259
Cdd:COG3290 173 RTELERLEEELEGVKELA---EALRAQRHDFRNHLHTISGLLQL--GEYDE----ALEYIDEISEELQELIDSLL----- 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 260 rpESIQVFDVAdvvrhiAMVMGAFGTLR--GVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEAIA---EPSGTVTIQ 333
Cdd:COG3290 239 --SRIGNPVLA------ALLLGKAARARerGIDLTIDIDSDLpDLPLSDTDLVTILGNLLDNAIEAVEklpEEERRVELS 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1199727195 334 AFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTS-GTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:COG3290 311 IRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTKLGeGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLP 385
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-401 |
3.13e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 70.95 E-value: 3.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAE-PSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKT--SGTGLGTMVTRKIIE 384
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKvENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPvgKGTGLGLSISYGIVE 80
|
90
....*....|....*..
gi 1199727195 385 GMKGTLTFHSAPGLGTE 401
Cdd:cd16976 81 EHGGRLSVANEEGAGAR 97
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
177-407 |
3.75e-15 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 77.76 E-value: 3.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 177 IENKI--QTLLLHR-----ELANKERlniiSELAAVIAHEVKNPLTVVRGFLQL-ALGSLDEKArpaMQIALTELDRANY 248
Cdd:PRK15347 373 LENKVaeRTQALAEakqraEQANKRK----SEHLTTISHEIRTPLNGVLGALELlQNTPLTAEQ---MDLADTARQCTLS 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 249 ---IISDYLNFAKPR-------PESIQVFDVADVvrhiAMVmgafgTLRGVEIRTDCSEGLLVNA--------DAGQLQQ 310
Cdd:PRK15347 446 llaIINNLLDFSRIEsgqmtlsLEETALLPLLDQ----AML-----TIQGPAQSKSLTLRTFVGAhvplylhlDSLRLRQ 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 311 ALMNLVKNGIEAIaePSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKT--SGTGLGTMVTRKIIEGMKG 388
Cdd:PRK15347 517 ILVNLLGNAVKFT--ETGGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADThsQGTGLGLTIASSLAKMMGG 594
|
250
....*....|....*....
gi 1199727195 389 TLTFHSAPGLGTEAVVKIP 407
Cdd:PRK15347 595 ELTLFSTPGVGSCFSLVLP 613
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
178-395 |
4.31e-15 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 77.03 E-value: 4.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 178 ENKIQtlllHRELANKERLNIISEL------AAV------IAHEVKNPLTVVRGFLQLALGSLDEKARPAMQIALTELD- 244
Cdd:COG4192 404 ETEIE----ERKRIEKNLRQTQDELiqaakmAVVgqtmtsLAHELNQPLNAMSMYLFSAKKALEQENYAQLPTSLDKIEg 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 245 ---RANYIISDYLNFAKPRPESIQVFDVADVVRHiAMVMgafgtlrgVEIRT---DCS----EGLLVNADAGQLQQALMN 314
Cdd:COG4192 480 lieRMDKIIKSLRQFSRKSDTPLQPVDLRQVIEQ-AWEL--------VESRAkpqQITlhipDDLMVQGDQVLLEQVLVN 550
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 315 LVKNGIEAIAEPSgTVTIQAFLQGETVLLSVRDTGVGMSAeqLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHS 394
Cdd:COG4192 551 LLVNALDAVATQP-QISVDLLSNAENLRVAISDNGNGWPL--VDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLAS 627
|
.
gi 1199727195 395 A 395
Cdd:COG4192 628 T 628
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
308-407 |
1.49e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 69.72 E-value: 1.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAEpSGTVTIQAFLQ---------------GETVLLSVRDTGVGMSAEQLRRMGTPFYTTKT--S 370
Cdd:cd16919 1 LELAILNLAVNARDAMPE-GGRLTIETSNQrvdadyalnyrdlipGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEvgK 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 1199727195 371 GTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16919 80 GTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
304-407 |
2.18e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 69.03 E-value: 2.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 304 DAGQLQQALMNLVKNGIEaIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTS------GTGLGTM 377
Cdd:cd16946 1 DRDRLQQLFVNLLENSLR-YTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSrnrasgGSGLGLA 79
|
90 100 110
....*....|....*....|....*....|
gi 1199727195 378 VTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16946 80 ICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
3.12e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 68.58 E-value: 3.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAEPSGTVTIQAFLQGETVLLSVR----------DTGVGMSAEQLRRMGTPFYTTKTSGTGLGTM 377
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGGEIILRTRTQRQVTLGHPRhrlalrvsviDNGPGIPPDLQDTIFYPMVSGRENGTGLGLA 80
|
90 100 110
....*....|....*....|....*....|
gi 1199727195 378 VTRKIIEGMKGTLTFHSAPGlGTEAVVKIP 407
Cdd:cd16918 81 IAQNIVSQHGGVIECDSQPG-HTVFSVSLP 109
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
199-409 |
5.22e-14 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 73.55 E-value: 5.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 199 ISELAAVIAHEVKNPLTVVRGFLQLALGSLDEKA--RPAMQIAL----TELDRANYIISDYLNFA-KPRPESiQVFDVAD 271
Cdd:PRK13557 163 LGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDadRGRMARSVenirAAAERAATLTQQLLAFArKQRLEG-RVLNLNG 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 272 VVRHIA-MVMGAFGTlrGVEIRTDCSEGLLvNA--DAGQLQQALMNLVKNGIEAIAEpSGTVTIQA-------------- 334
Cdd:PRK13557 242 LVSGMGeLAERTLGD--AVTIETDLAPDLW-NCriDPTQAEVALLNVLINARDAMPE-GGRVTIRTrnveiededlamyh 317
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1199727195 335 -FLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTS--GTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAV 409
Cdd:PRK13557 318 gLPPGRYVSIAVTDTGSGMPPEILARVMDPFFTTKEEgkGTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFPAS 395
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
304-407 |
7.66e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 67.18 E-value: 7.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 304 DAGQLQQALMNLVKNGIEAIAE---PSGTVTIQAFL-QGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVT 379
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGrpsDVGEVRIRVEAdQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAIV 80
|
90 100
....*....|....*....|....*...
gi 1199727195 380 RKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16944 81 KKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
204-411 |
8.05e-14 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 72.74 E-value: 8.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 204 AVIAHEVKNPLTVVRGFL-----QLALGSLDEKARPAMQialTELDRANYIISDYLNFAK----PRPESIQVFDVA---D 271
Cdd:PRK11006 209 ANVSHELRTPLTVLQGYLemmqdQPLEGALREKALHTMR---EQTQRMEGLVKQLLTLSKieaaPTIDLNEKVDVPmmlR 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 272 VVRHIAMVMGAfgtlRGVEIRTDCSEGLLVNADAGQLQQALMNLVKNGIEAIaePSGT---VTIQAFLQGetVLLSVRDT 348
Cdd:PRK11006 286 VLEREAQTLSQ----GKHTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHT--PEGThitVRWQRVPQG--AEFSVEDN 357
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1199727195 349 GVGMSAEQLRRMGTPFY------TTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAVLV 411
Cdd:PRK11006 358 GPGIAPEHIPRLTERFYrvdkarSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLPERLI 426
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
312-407 |
3.29e-12 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 68.02 E-value: 3.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 312 LMNLVKNGIEAIAE-PSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGTGLGTMVTRKIIEGMKGTL 390
Cdd:PRK11086 438 LGNLIENALEAVGGeEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVENLGGSI 517
|
90
....*....|....*..
gi 1199727195 391 TFHSAPGLGTEAVVKIP 407
Cdd:PRK11086 518 AVESEPGVGTQFFVQIP 534
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
301-415 |
2.08e-11 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 65.73 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 301 VNADAGQLQQALMNLVKNGIEAIAEPSGTVTIQAfLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTS-------GTG 373
Cdd:PRK11091 392 VITDGTRLRQILWNLISNAVKFTQQGGVTVRVRY-EEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDShggkpatGTG 470
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1199727195 374 LGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIPAVLVKEVV 415
Cdd:PRK11091 471 IGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHAPAVAEEV 512
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
198-400 |
2.39e-11 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 65.64 E-value: 2.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 198 IISELAAVIAHEVKNPLTVVRGFL-QLALGSLDEKARPAMQIalteLDR-ANY---IISDYLNFAKPRP-----ESIQvF 267
Cdd:PRK11107 292 IKSEFLANMSHELRTPLNGVIGFTrQTLKTPLTPTQRDYLQT----IERsANNllaIINDILDFSKLEAgklvlENIP-F 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 268 DVADVVRHIAMVMGAFGTLRGVEIRTDCSEGL--LVNADAGQLQQALMNLVKNGIEAIaePSGTVTIQAFLQGET---VL 342
Cdd:PRK11107 367 SLRETLDEVVTLLAHSAHEKGLELTLNIDPDVpdNVIGDPLRLQQIITNLVGNAIKFT--ESGNIDILVELRALSntkVQ 444
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1199727195 343 L--SVRDTGVGMSAEQLRRMGTPFYTTKTS------GTGLGTMVTRKIIEGMKGTLTFHSAPGLGT 400
Cdd:PRK11107 445 LevQIRDTGIGISERQQSQLFQAFRQADASisrrhgGTGLGLVITQKLVNEMGGDISFHSQPNRGS 510
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
314-407 |
4.70e-11 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 64.27 E-value: 4.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 314 NLVKNGIEAIAEPsGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFyTTKTSGTGLGTMVTRKIIE---GMKGTL 390
Cdd:COG2972 347 NAIEHGIEPKEGG-GTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEEL-SSKGEGRGIGLRNVRERLKlyyGEEYGL 424
|
90
....*....|....*..
gi 1199727195 391 TFHSAPGLGTEAVVKIP 407
Cdd:COG2972 425 EIESEPGEGTTVTIRIP 441
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
314-407 |
9.00e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 58.45 E-value: 9.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 314 NLVKNGIEAIA---EPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTK-TSGTGLGTMVTRKIIEGMKGT 389
Cdd:cd16915 7 NLIDNALDALAatgAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKgQGERGIGLALVRQSVERLGGS 86
|
90
....*....|....*...
gi 1199727195 390 LTFHSAPGLGTEAVVKIP 407
Cdd:cd16915 87 ITVESEPGGGTTFSIRIP 104
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
200-262 |
1.28e-10 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 56.84 E-value: 1.28e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1199727195 200 SELAAVIAHEVKNPLTVVRGFLQLAL-GSLDEKARPAMQIALTELDRANYIISDYLNFAKPRPE 262
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRdEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
200-262 |
1.61e-10 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 56.42 E-value: 1.61e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1199727195 200 SELAAVIAHEVKNPLTVVRGFLQLAL-GSLDEKARPAMQIALTELDRANYIISDYLNFAKPRPE 262
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLLdTELSEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
66-408 |
2.00e-10 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 62.23 E-value: 2.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 66 DLRMIPLILAVVYGGWRAGLIAAVPALLYRAQLGGGSVWLELAAGAVSLGICFVLARSFLRFAPRQRILLCMLLSFLSFL 145
Cdd:COG3920 174 AAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEELERRRRARGLGRL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 146 PLGLAVNASHLDLLLVQGALHILGIGIcSYLIENKIQTLLLHRELANKErlniiselaavIAHEVKNPLTVVRGFLQLAL 225
Cdd:COG3920 254 LLLLLLLLLLLRALLLLAAGIRLVITE-RKRAEEELEASLEEKELLLRE-----------LHHRVKNNLQVVSSLLRLQA 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 226 GSLDEkarPAMQIALTELdrANYIIS-----DYLNfakpRPESIQVFDVADVVRHIAMVMGAFGTLRGVEIRTDCsEGLL 300
Cdd:COG3920 322 RRADD---PEAREALEES--QNRIQAlalvhELLY----QSEDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDG-PDVE 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 301 VNADAGQ-----LQQALMNLVKNGieAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEqlrrmgtpfyTTKTSGTGLG 375
Cdd:COG3920 392 LPADAAVplgliLNELVTNALKHA--FLSGEGGRIRVSWRREDGRLRLTVSDNGVGLPED----------VDPPARKGLG 459
|
330 340 350
....*....|....*....|....*....|...
gi 1199727195 376 TMVTRKIIEGMKGTLTFHSAPglGTEAVVKIPA 408
Cdd:COG3920 460 LRLIRALVRQLGGTLELDRPE--GTRVRITFPL 490
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
182-399 |
2.27e-10 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 61.89 E-value: 2.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 182 QTLLLHRELAN-KERLNIISELAAVIAHEVKNPLTVVRGFLQ-LALGSLDE--KARPAMQIALTELDRA-----NYIISD 252
Cdd:PRK09303 133 ELFVLRQENETlLEQLKFKDRVLAMLAHDLRTPLTAASLALEtLELGQIDEdtELKPALIEQLQDQARRqleeiERLITD 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 253 YLNFAKPRPESIQV----FDVADVVRHIAMVMGAFGTLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEaIAEPS 327
Cdd:PRK09303 213 LLEVGRTRWEALRFnpqkLDLGSLCQEVILELEKRWLAKSLEIQTDIPSDLpSVYADQERIRQVLLNLLDNAIK-YTPEG 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 328 GTVTIQAF---LQgeTVLLSVRDTGVGMSAEQLRRMgtpFYTT-------KTSGTGLGTMVTRKIIEGMKGTLTFHSAPG 397
Cdd:PRK09303 292 GTITLSMLhrtTQ--KVQVSICDTGPGIPEEEQERI---FEDRvrlprdeGTEGYGIGLSVCRRIVRVHYGQIWVDSEPG 366
|
..
gi 1199727195 398 LG 399
Cdd:PRK09303 367 QG 368
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
307-407 |
2.56e-10 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 59.13 E-value: 2.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 307 QLQQALMNLVKN----GIEAIAE-------PSGTVTIQAFLQGETVLLSVRDTGVGM---------------SAEQLRRM 360
Cdd:cd16916 38 KLADPLTHLLRNavdhGIEAPEErlaagkpPEGTITLRAEHQGNQVVIEVSDDGRGIdrekirekaiergliTADEAATL 117
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1199727195 361 GT---------PFYTTKT-----SGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16916 118 SDdevlnlifaPGFSTAEqvtdvSGRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-408 |
4.55e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 56.57 E-value: 4.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNgieAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFY------TTKTSGTGLGTMVTRK 381
Cdd:cd16949 1 LARALENVLRN---ALRYSPSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLGLAIAER 77
|
90 100
....*....|....*....|....*..
gi 1199727195 382 IIEGMKGTLTFHSAPGLGTEAVVKIPA 408
Cdd:cd16949 78 AIEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
200-258 |
8.43e-10 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 54.53 E-value: 8.43e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1199727195 200 SELAAVIAHEVKNPLTVVRGFLQLALGSL--DEKARPAMQIALTELDRANYIISDYLNFAK 258
Cdd:cd00082 5 GEFLANVSHELRTPLTAIRGALELLEEELldDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
204-407 |
1.22e-09 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 59.65 E-value: 1.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 204 AVIAHEVKNPLTVVRGFL---QLALGSLDEKARPAMQ--IA-LTEL--DRANYIISDYLNFAKpRPESIqvfdvaDVVRH 275
Cdd:PRK10549 245 ADISHELRTPLAVLRGELeaiQDGVRKFTPESVASLQaeVGtLTKLvdDLHQLSLSDEGALAY-RKTPV------DLVPL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 276 IAMVMGAFG---TLRGVEIRTDCSEGLLVNADAGQLQQALMNLVKNGIEAIAEPsGTVTIQAFLQGETVLLSVRDTGVGM 352
Cdd:PRK10549 318 LEVAGGAFRerfASRGLTLQLSLPDSATVFGDPDRLMQLFNNLLENSLRYTDSG-GSLHISAEQRDKTLRLTFADSAPGV 396
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1199727195 353 SAEQLRRMGTPFYTTKTS------GTGLGTMVTRKIIEGMKGTLTF-HSAPGlGTEAVVKIP 407
Cdd:PRK10549 397 SDEQLQKLFERFYRTEGSrnrasgGSGLGLAICLNIVEAHNGRIIAaHSPFG-GVSITVELP 457
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
200-407 |
1.24e-09 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 60.30 E-value: 1.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 200 SELAAVIAHEVKNPLTVVRGFLQLALGS-LDEKARPAMQIALTELDRANYIISDYLNFAKPRPESIQV------FDVADV 272
Cdd:PRK11466 445 SAFLAAMSHEIRTPLYGILGTAQLLADNpALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGGKNVsvsdepFEPRPL 524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 273 VRHIAMVMGAFGTLRGVEIRTDCSEGL--LVNADAGQLQQALMNLVKNGIEAIAEpsGTVTIQAFLQGETVLLSVRDTGV 350
Cdd:PRK11466 525 LESTLQLMSGRVKGRPIRLATDIADDLptALMGDPRRIRQVITNLLSNALRFTDE--GSIVLRSRTDGEQWLVEVEDSGC 602
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1199727195 351 GMSAEQLRRMGTPFY--TTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:PRK11466 603 GIDPAKLAEIFQPFVqvSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
2.85e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 54.26 E-value: 2.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAE-PSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKT----SGTGLGTMVTRKI 382
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPrRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSreeyEGTGVGLAIVRKI 80
|
90 100
....*....|....*....|....*
gi 1199727195 383 IEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16921 81 IERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
200-407 |
3.01e-09 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 58.63 E-value: 3.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 200 SELAAVIAHEVKNPLT--VVRGFLQLALGSLDEKARPAMQIALTELDRANYIISDYLNFAKP-----RPESiQVFDVADV 272
Cdd:PRK09835 263 SNFSADIAHEIRTPITnlITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQAdnnqlIPEK-KMLDLADE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 273 VRHIAMVMGAFGTLRGVEIRTDcSEGLLVNADAGQLQQALMNLVKNGIEAIaePSG-TVTIQAFLQGETVLLSVRDTGVG 351
Cdd:PRK09835 342 VGKVFDFFEAWAEERGVELRFV-GDPCQVAGDPLMLRRAISNLLSNALRYT--PAGeAITVRCQEVDHQVQLVVENPGTP 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1199727195 352 MSAEQLRRMGTPFYTT------KTSGTGLGTMVTRKIIEGMKGTLTFHSAPgLGTEAVVKIP 407
Cdd:PRK09835 419 IAPEHLPRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVVAHKGTVAVTSDA-RGTRFVISLP 479
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
4.04e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 53.75 E-value: 4.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAiAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFY------TTKTSGTGLGTMVTRK 381
Cdd:cd16952 1 LRSAFSNLVSNAVKY-TPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTGLGLAIVKH 79
|
90 100
....*....|....*....|....*.
gi 1199727195 382 IIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16952 80 VMSRHDARLLIASELGKGSRFTCLFP 105
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
178-407 |
4.46e-09 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 56.94 E-value: 4.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 178 ENKIQTLLLHRELANKERLNIISELAAVIAHEvknpLTVVR---GFLQLALGSLDEKARPAMQIALTELDRANY----II 250
Cdd:COG4585 37 ELERELAARAEEAREEERRRIARELHDGVGQS----LSAIKlqlEAARRLLDADPEAAREELEEIRELAREALAelrrLV 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 251 SDYlnfakpRPESIQVFDVADVVRHIAmvmGAFGTLRGVEIRTDCsEGLLVNADAGQ-------LQQALMNLVKNGieai 323
Cdd:COG4585 113 RGL------RPPALDDLGLAAALEELA---ERLLRAAGIRVELDV-DGDPDRLPPEVelalyriVQEALTNALKHA---- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 324 aePSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRmgtpfyttktSGTGLGTMVTRkiIEGMKGTLTFHSAPGLGTEAV 403
Cdd:COG4585 179 --GATRVTVTLEVDDGELTLTVRDDGVGFDPEAAPG----------GGLGLRGMRER--AEALGGTLTIGSAPGGGTRVR 244
|
....
gi 1199727195 404 VKIP 407
Cdd:COG4585 245 ATLP 248
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
188-407 |
7.06e-09 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 57.23 E-value: 7.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 188 RELANKERLniiseLAAVIAHEVKNPLTVVRgflqLA---LGSLDEKARPAMqiaLTELDRANYIISDYLNFAKP-RPES 263
Cdd:PRK09467 223 KQLEDDRTL-----LMAGVSHDLRTPLTRIR----LAtemMSEEDGYLAESI---NKDIEECNAIIEQFIDYLRTgQEMP 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 264 IQVFDVADVVRHIAMVMGAfgtlRGVEIRTDCSEGLL-VNADAGQLQQALMNLVKNgieAIAEPSGTVTIQAFLQGETVL 342
Cdd:PRK09467 291 MEMADLNALLGEVIAAESG----YEREIETALQPGPIeVPMNPIAIKRALANLVVN---AARYGNGWIKVSSGTEGKRAW 363
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1199727195 343 LSVRDTGVGMSAEQLRRMGTPFytTK------TSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:PRK09467 364 FQVEDDGPGIPPEQLKHLFQPF--TRgdsargSSGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLP 432
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
207-404 |
7.62e-09 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 57.35 E-value: 7.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 207 AHEVKNPLTVVR---GFLQLALGslDEKARpamQIALTEL----DRANYIISDYLNFAK----PRPESIQVFDVADVVRH 275
Cdd:PRK10337 245 AHELRSPLAALKvqtEVAQLSDD--DPQAR---KKALLQLhagiDRATRLVDQLLTLSRldslDNLQDVAEIPLEDLLQS 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 276 IAMVMGAFGTLRGVEIRtdcsegLLVNAD----AGQ-LQQALM--NLVKNGIEaIAEPSGTVTIQAFLQGetvlLSVRDT 348
Cdd:PRK10337 320 AVMDIYHTAQQAGIDVR------LTLNAHpvirTGQpLLLSLLvrNLLDNAIR-YSPQGSVVDVTLNARN----FTVRDN 388
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1199727195 349 GVGMSAEQLRRMGTPFYT---TKTSGTGLGTMVTRKI--IEGMkgTLTFHSAPGLGTEAVV 404
Cdd:PRK10337 389 GPGVTPEALARIGERFYRppgQEATGSGLGLSIVRRIakLHGM--NVSFGNAPEGGFEAKV 447
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
301-405 |
6.37e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 50.48 E-value: 6.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 301 VNADAGQLQQALMNLVKNGIEAiaEPSGTVtIQAFLQGE-TVLLSVRDTGVGMSAEQLRRMGTPFY---TTKTSGTGLGT 376
Cdd:cd16940 7 VQGDALLLFLLLRNLVDNAVRY--SPQGSR-VEIKLSADdGAVIRVEDNGPGIDEEELEALFERFYrsdGQNYGGSGLGL 83
|
90 100
....*....|....*....|....*....
gi 1199727195 377 MVTRKIIEGMKGTLTFHSAPGLGTEAVVK 405
Cdd:cd16940 84 SIVKRIVELHGGQIFLGNAQGGGLEAWVR 112
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
304-407 |
7.87e-08 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 50.18 E-value: 7.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 304 DAGQLQQALMNLVKNGIEAiaEPSG---TVTIQAFlQGETVLLSVRDTGVGMSAEQLRRMGTPFY------TTKTSGTGL 374
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKF--TPDGgriRCILEKF-RLNRFLLTVSDSGPGIPPNLREEIFERFRqgdgssTRAHGGTGL 77
|
90 100 110
....*....|....*....|....*....|...
gi 1199727195 375 GTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16925 78 GLSIVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
304-406 |
1.03e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 49.77 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 304 DAGQLQQALMNLVKNGIeAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYT-----TKTSGTGLGTMV 378
Cdd:cd16945 1 DPFLLRQAINNLLDNAI-DFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGLGLAF 79
|
90 100
....*....|....*....|....*...
gi 1199727195 379 TRKIIEGMKGTLTFHSAPGlGTEAVVKI 406
Cdd:cd16945 80 VQEVAQLHGGRITLRNRPD-GVLAFLTL 106
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
1.08e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 49.75 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNgieAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFY----TTKTSGTGLGTMVTRKII 383
Cdd:cd16950 1 LKRVLSNLVDN---ALRYGGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYrgdnARGTSGTGLGLAIVQRIS 77
|
90 100
....*....|....*....|....
gi 1199727195 384 EGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16950 78 DAHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
1.15e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 49.88 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSG------TGLGTMVTRK 381
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANeafgqhSGLGLSISRQ 80
|
90 100 110
....*....|....*....|....*....|
gi 1199727195 382 IIEGMKGTLT--FHSAPGL--GTEAVVKIP 407
Cdd:cd16953 81 IIEAHGGISVaeNHNQPGQviGARFTVQLP 110
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
304-406 |
2.44e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 48.61 E-value: 2.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 304 DAGQLQQALMNLVKNGIEaIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYTTKTSGT-----GLGTMV 378
Cdd:cd16975 1 DTLLLSRALINIISNACQ-YAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRsgghyGMGLYI 79
|
90 100
....*....|....*....|....*...
gi 1199727195 379 TRKIIEGMKGTLTFHSAPGLGTEAVVKI 406
Cdd:cd16975 80 AKNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
304-401 |
3.08e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 48.44 E-value: 3.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 304 DAGQLQQALMNLVKNGIEAIAEpSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYT------TKTSgTGLGTM 377
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQ-GGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTgengrnFQES-TGMGLY 79
|
90 100
....*....|....*....|....
gi 1199727195 378 VTRKIIEGMKGTLTFHSAPGLGTE 401
Cdd:cd16948 80 LVKKLCDKLGHKIDVESEVGEGTT 103
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
176-407 |
4.17e-07 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 52.35 E-value: 4.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 176 LIENKIQTLLLHR--ELA--NKERLNIISELAAVIAHEVKNPLTVVRG---FLQLALGSLDEK-ARPAMQIALTELDRAN 247
Cdd:PRK10490 637 LIANALERLTLTAseEQArlASEREQLRNALLAALSHDLRTPLTVLFGqaeILTLDLASEGSPhARQASEIRQQVLNTTR 716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 248 yIISDYLNFAKPRPESIQVFDVADVVRHI---AMVMGAFGtLRGVEIRTDCSEGL-LVNADAGQLQQALMNLVKNGIEaI 323
Cdd:PRK10490 717 -LVNNLLDMARIQSGGFNLRKEWLTLEEVvgsALQMLEPG-LSGHPINLSLPEPLtLIHVDGPLFERVLINLLENAVK-Y 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 324 AEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFYT-TKTS---GTGLGTMVTRKIIEGMKGTLTFHSAPGLG 399
Cdd:PRK10490 794 AGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARgNKESaipGVGLGLAICRAIVEVHGGTIWAENRPEGG 873
|
....*...
gi 1199727195 400 TEAVVKIP 407
Cdd:PRK10490 874 ACFRVTLP 881
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
311-407 |
2.32e-06 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 49.80 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 311 ALMNLVKN----GIEAIAE-------PSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRR----MG--TP---------- 363
Cdd:COG0643 281 PLVHLVRNavdhGIETPEErlaagkpETGTITLSAYHEGGRVVIEVSDDGRGLDLEKIRAkaieKGliTAeeaaalsdee 360
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1199727195 364 ---------FYT----TKTSGTGLGtM-VTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:COG0643 361 llelifapgFSTaeevTDLSGRGVG-MdVVKTNIEALGGTIEIESEPGKGTTFTLRLP 417
|
|
| 5TM-5TMR_LYT |
pfam07694 |
5TMR of 5TMR-LYT; This entry represents the transmembrane region of the 5TM-LYT (5TM Receptors ... |
34-126 |
4.06e-06 |
|
5TMR of 5TMR-LYT; This entry represents the transmembrane region of the 5TM-LYT (5TM Receptors of the LytS-YhcK type).
Pssm-ID: 429599 Cd Length: 170 Bit Score: 46.79 E-value: 4.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 34 YRRKHQMLVGVLGGTTAMLCLSLPVKIDN-VLWDLRMIPLILAVVYGGWRAGLIAAVPALLYRAQLGGGSvWLELAAGAV 112
Cdd:pfam07694 13 LRLKDKVLLGLIFGLFSILGTYTGIEIEPgAIANTRAVGIVLAGLLGGPIVGLIAGLIAGLHRYFLGGFT-ALACGISTI 91
|
90
....*....|....
gi 1199727195 113 SLGICFVLARSFLR 126
Cdd:pfam07694 92 LAGLIAGLLHRRLK 105
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-395 |
1.17e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 43.91 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIeAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPFY----TTKTSGTGLGTMVTRKII 383
Cdd:cd16923 1 LQRVFSNLLSNAI-KYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdnSRNTEGAGLGLSIAKAII 79
|
90
....*....|..
gi 1199727195 384 EGMKGTLTFHSA 395
Cdd:cd16923 80 ELHGGSASAEYD 91
|
|
| HATPase_YehU-like |
cd16956 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
2.08e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.
Pssm-ID: 340432 [Multi-domain] Cd Length: 101 Bit Score: 43.19 E-value: 2.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGIEAIAEpSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGTPfyttKTSGTGLgTMVTRKIIE--G 385
Cdd:cd16956 6 LQPIVENAVKHGLSGLLD-GGRVEITARLDGQHLLLEVEDNGGGMDPDTLARILIR----SSNGLGL-NLVDKRLRQafG 79
|
90 100
....*....|....*....|..
gi 1199727195 386 MKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16956 80 NDYGLDIECAPGEGTRITIRLP 101
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
3.27e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 42.16 E-value: 3.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 308 LQQALMNLVKNGieaiaePSGTVTIQAFLQGETVLLSVRDTGVGMSAEQlrrmgtpfyTTKTSGTGLGTMVTRkiIEGMK 387
Cdd:cd16917 5 VQEALTNALKHA------GASRVRVTLSYTADELTLTVVDDGVGFDGPA---------PPGGGGFGLLGMRER--AELLG 67
|
90 100
....*....|....*....|
gi 1199727195 388 GTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16917 68 GTLTIGSRPGGGTRVTARLP 87
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
312-407 |
1.31e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 40.89 E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 312 LMNLVKNGIEAIAEPS---GTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRMGtpfyTTKTSGTGLGTMVTRKIIEGMKG 388
Cdd:cd16924 6 LQPLVENAIQHGLSPLtdkGVVTISALKEDNHVMIEVEDNGRGIDPKVLNILG----KKPKEGNGIGLYNVHQRLILLFG 81
|
90 100
....*....|....*....|..
gi 1199727195 389 ---TLTFHSAPGLGTEAVVKIP 407
Cdd:cd16924 82 edyGIHIASEPDKGTRITFTIP 103
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
302-406 |
2.70e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 40.57 E-value: 2.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 302 NADAGQLQQALMNLVKNGIEAIAEpsGTVTIQAFLQGET-VLLSVRDTGVGMSAEQLRRMGTPFYTTKTS------GTGL 374
Cdd:cd16947 15 NANTEALQRILKNLISNAIKYGSD--GKFLGMTLREDEKhVYIDIWDKGKGISETEKDHVFERLYTLEDSrnsakqGNGL 92
|
90 100 110
....*....|....*....|....*....|..
gi 1199727195 375 GTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKI 406
Cdd:cd16947 93 GLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| HATPase_SpoIIAB-like |
cd16942 |
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein ... |
310-405 |
5.44e-04 |
|
Histidine kinase-like ATPase domain of SpoIIAB, an anti sigma-F factor and serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of SpoIIAB, an anti sigma-F factor and a serine-protein kinase involved in regulating sigma-F during sporulation in Bacilli where, early in sporulation, the cell divides into two unequal compartments: a larger mother cell and a smaller forespore. Sigma-F transcription factor is activated in the forespore directly after the asymmetric septum forms, and its spatial and temporal activation is required for sporulation. Free sigma-F can associate with the RNA polymerase core and activate transcription of the sigma-F regulon, its regulation may comprise a partner-switching mechanism involving SpoIIAB, SpoIIAA, and sigma-F as follows: SpoIIAB can form alternative complexes with either: i) sigma-F, holding it in an inactive form and preventing its association with RNA polymerase, or ii) unphosphorylated SpoIIAA and a nucleotide, either ATP or ADP. In the presence of ATP, SpoIIAB acts as a kinase to specifically phosphorylate a serine residue of SpoIIAA; this phosphorylated form has low affinity for SpoIIAB and dissociates, making SpoIIAB available to capture sigma-F. SpoIIAA may then be dephosphorylated by a SpoIIE serine phosphatase and be free to attack the SpoIIAB sigma-F complex to induce the release of sigma-F.
Pssm-ID: 340418 [Multi-domain] Cd Length: 135 Bit Score: 39.83 E-value: 5.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 310 QALMNLVKNGIEAiaEPSGTVTIQAFLQGETVLLSVRDTGVGM-SAEQLRRmgtPFYTTKT----SGTGLGTMvtrkiiE 384
Cdd:cd16942 45 EAVTNAIIHGYNN--DPNGIVSISVIIEDGVVHLTVRDEGVGIpDIEEARQ---PLFTTKPelerSGMGFTIM------E 113
|
90 100
....*....|....*....|.
gi 1199727195 385 GMKGTLTFHSAPGLGTEAVVK 405
Cdd:cd16942 114 NFMDEVIVESEVNKGTTVYLK 134
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
287-406 |
6.54e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 39.54 E-value: 6.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 287 RGVEIRTDCSEGLLVNADAGQLQQALMNLVKNgieAIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRM---GTP 363
Cdd:cd16954 17 KGVSISLDISPELRFPGERNDLMELLGNLLDN---ACKWCLEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIfqrGQR 93
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1199727195 364 FyTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKI 406
Cdd:cd16954 94 L-DEQRPGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
272-407 |
1.13e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 38.94 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 272 VVRHIAMVMGAFGTLRGVEIRTDCSEGLLVNADAGQLQQALMNLVKNGIEAIAEP--SGTVTIQAFLQGETVLLSVRDTG 349
Cdd:cd16951 4 YINRIASAINAIHAVGDIRINITGDTGPVSSEVATAIGLVVNELLQNALKHAFSDreGGTITIRSVVDGDYLRITVIDDG 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1199727195 350 VGMsaeqlrrmgtPFYTTKTSGTGLGTMVTRKIIEGMKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16951 84 VGL----------PQDEDWPNKGSLGLQIVRSLVEGELKAFLEVQSAENGTRVNIDIP 131
|
|
| HATPase_c_3 |
pfam13589 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ... |
311-387 |
1.29e-03 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain] Cd Length: 135 Bit Score: 38.85 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 311 ALMNLVKNGIEAIAEpsgTVTIQA-FLQGETVLLSVRDTGVGMSAEQLR---RMGTPFYTTKTSGTGLGtmvtRKIIeGM 386
Cdd:pfam13589 4 ALAELIDNSIDADAT---NIKIEVnKNRGGGTEIVIEDDGHGMSPEELInalRLATSAKEAKRGSTDLG----RYGI-GL 75
|
.
gi 1199727195 387 K 387
Cdd:pfam13589 76 K 76
|
|
| HATPase_RsbT-like |
cd16934 |
Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine ... |
265-406 |
3.55e-03 |
|
Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.
Pssm-ID: 340411 [Multi-domain] Cd Length: 117 Bit Score: 36.96 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1199727195 265 QVFDVADVVRHIAMVMGaFGTLRGVEIRTDCSE---GLLVNADAGQLqqalmnlvknGIEAIAEPsGTVTIQaflqgetv 341
Cdd:cd16934 1 DVVDARRAARELARRLG-LSEVRQAEIATAVTElarNLLKHAGGGQV----------LLEVVAEG-GRVALE-------- 60
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1199727195 342 lLSVRDTGVGMsAEQLRRMGTPFYTTKTSGTGLGTmvtrkiIEGMKGTLTFHSAPGLGTEAVVKI 406
Cdd:cd16934 61 -ILAVDQGPGI-ADVDEALRDGFSTGGGLGLGLGG------VRRLADEFDLHSAPGRGTVVVARK 117
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
304-377 |
8.49e-03 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 36.04 E-value: 8.49e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1199727195 304 DAGQLQQALMNLVKNGIE--AIAEPSGTVTIQAFLQGETVLLSVRDTGVGMSAEQLRRmgtPFYTTKTSGTGLGTM 377
Cdd:COG2172 31 DADDLVLAVSEAVTNAVRhaYGGDPDGPVEVELELDPDGLEIEVRDEGPGFDPEDLPD---PYSTLAEGGRGLFLI 103
|
|
| HATPase_YpdA-like |
cd16955 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
308-407 |
8.89e-03 |
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Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli YpdA, a HK of the two-component system (TCS) YpdA-YpdB which is involved in a nutrient sensing regulatory network with YehU-YehT. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and some have a GAF sensor domain; some contain a DUF3816 domain; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340431 [Multi-domain] Cd Length: 102 Bit Score: 35.51 E-value: 8.89e-03
10 20 30 40 50 60 70 80
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gi 1199727195 308 LQQALMNLVKNGIEAiAEPSGTVTIQAFLQGE-TVLLSVRDTGVGMSAEQLRRMgtpfYTTKTSGTGLGTM-VTRKIIEG 385
Cdd:cd16955 6 IQPLVENAIVHGIQE-KKGKGVVKISVKKQLKnRLHIAVEDNGIGISPKVIERV----EQDEMPGNKIGLLnVHQRLKLG 80
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90 100
....*....|....*....|..
gi 1199727195 386 MKGTLTFHSAPGLGTEAVVKIP 407
Cdd:cd16955 81 YGEGLHIRSRPDPGTLIAFYIP 102
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