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Conserved domains on  [gi|1207695457|ref|WP_088054251|]
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MULTISPECIES: ABC-three component system middle component 7 [Bacillus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MC6 super family cl46267
ABC-three component (ABC-3C) system Middle Component 6; Middle Components (MCs) of the ABC-3C ...
 3-71 4.02e-18

ABC-three component (ABC-3C) system Middle Component 6; Middle Components (MCs) of the ABC-3C biological conflict systems occupy the central position between the catalytic effector and ABC ATPases of the systems. MCs are defined by distinctive patterns of conserved charged residues. As some MCs are HTH domains, they are predicted to function akin to kleisins as DNA-binding partners for the ABC ATPases, assisting in recognition and responding to invasive elements such as DNA viruses. MC6 is a MC unifiable with the HTH fold.


The actual alignment was detected with superfamily member pfam20292:

Pssm-ID: 480607  Cd Length: 69  Bit Score: 70.40  E-value: 4.02e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207695457  3 VPNKVIRFNESIIGKVIYILEELSNGDLSIENLYTNTQEYFEGIDEFIFSLDVLYILDSIQVDFEEGVV 71
Cdd:pfam20292  1 LPNKVTSYSESILAKFPKILSELEQGDMTVAELYKKVRSKFDDVGEFLEALDCLYALGKIELDEEGEVL 69
 
Name Accession Description Interval E-value
MC7 pfam20292
ABC-three component (ABC-3C) system Middle Component 7; Middle Components (MCs) of the ABC-3C ...
 3-71 4.02e-18

ABC-three component (ABC-3C) system Middle Component 7; Middle Components (MCs) of the ABC-3C biological conflict systems occupy the central position between the catalytic effector and ABC ATPases of the systems. MCs are defined by distinctive patterns of conserved charged residues. As some MCs are HTH domains, they are predicted to function akin to kleisins as DNA-binding partners for the ABC ATPases, assisting in recognition and responding to invasive elements such as DNA viruses. MC7 is a MC unifiable with the HTH fold.


Pssm-ID: 466442  Cd Length: 69  Bit Score: 70.40  E-value: 4.02e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207695457  3 VPNKVIRFNESIIGKVIYILEELSNGDLSIENLYTNTQEYFEGIDEFIFSLDVLYILDSIQVDFEEGVV 71
Cdd:pfam20292  1 LPNKVTSYSESILAKFPKILSELEQGDMTVAELYKKVRSKFDDVGEFLEALDCLYALGKIELDEEGEVL 69
 
Name Accession Description Interval E-value
MC7 pfam20292
ABC-three component (ABC-3C) system Middle Component 7; Middle Components (MCs) of the ABC-3C ...
 3-71 4.02e-18

ABC-three component (ABC-3C) system Middle Component 7; Middle Components (MCs) of the ABC-3C biological conflict systems occupy the central position between the catalytic effector and ABC ATPases of the systems. MCs are defined by distinctive patterns of conserved charged residues. As some MCs are HTH domains, they are predicted to function akin to kleisins as DNA-binding partners for the ABC ATPases, assisting in recognition and responding to invasive elements such as DNA viruses. MC7 is a MC unifiable with the HTH fold.


Pssm-ID: 466442  Cd Length: 69  Bit Score: 70.40  E-value: 4.02e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207695457  3 VPNKVIRFNESIIGKVIYILEELSNGDLSIENLYTNTQEYFEGIDEFIFSLDVLYILDSIQVDFEEGVV 71
Cdd:pfam20292  1 LPNKVTSYSESILAKFPKILSELEQGDMTVAELYKKVRSKFDDVGEFLEALDCLYALGKIELDEEGEVL 69
MC6 pfam20293
ABC-three component (ABC-3C) system Middle Component 6; Middle Components (MCs) of the ABC-3C ...
 3-72 2.11e-04

ABC-three component (ABC-3C) system Middle Component 6; Middle Components (MCs) of the ABC-3C biological conflict systems occupy the central position between the catalytic effector and ABC ATPases of the systems. MCs are defined by distinctive patterns of conserved charged residues. As some MCs are HTH domains, they are predicted to function akin to kleisins as DNA-binding partners for the ABC ATPases, assisting in recognition and responding to invasive elements such as DNA viruses. MC6 is a MC unifiable with the HTH fold.


Pssm-ID: 466443  Cd Length: 76  Bit Score: 35.70  E-value: 2.11e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207695457  3 VPNKVIRFNESIIGKVIYILEELS-NGDLSIENLYTNTQEYFE----GIDEFIFSLDVLYILDSIQVDfEEGVVK 72
Cdd:pfam20293  1 LPTKHIHPERSLYYVGAIVLALLKkNPELTVDELWERLKSWRSlsniSFDWFVLALDWLFLIGAIELN-DGGLVR 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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