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Conserved domains on  [gi|1208968233|ref|WP_088230174|]
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MULTISPECIES: UDP-N-acetylmuramate dehydrogenase [Bacillus]

Protein Classification

UDP-N-acetylmuramate dehydrogenase( domain architecture ID 11486939)

UDP-N-acetylmuramate dehydrogenase is responsible for the synthesis of UDP-N-acetylmuramic acid in bacterial cell wall biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
murB PRK13905
UDP-N-acetylmuramate dehydrogenase;
4-301 5.43e-165

UDP-N-acetylmuramate dehydrogenase;


:

Pssm-ID: 237553 [Multi-domain]  Cd Length: 298  Bit Score: 459.96  E-value: 5.43e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233   4 LVNELIKANVGRVLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRL 83
Cdd:PRK13905    1 LLKELLPALRGRLLENEPLARYTSFRVGGPADYLVEPADIEDLQEFLKLLKENNIPVTVLGNGSNLLVRDGGIRGVVIRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  84 GEGLDHLEVENHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEW 163
Cdd:PRK13905   81 GKGLNEIEVEGNRITAGAGAPLIKLARFAAEAGLSGLEFAAGIPGTVGGAVFMNAGAYGGETADVLESVEVLDRDGEIKT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 164 LMNSEMEFSYRTSVLQTKRpGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAG 243
Cdd:PRK13905  161 LSNEELGFGYRHSALQEEG-LIVLSATFQLEPGDKEEIKARMDELLARREATQPLEYPSAGSVFKNPPGHFAGKLIEEAG 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1208968233 244 LRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIGR 301
Cdd:PRK13905  240 LKGYRIGGAQVSEKHANFIINTGGATAADIEDLIEHVQKTVKEKFGVELEWEVRIIGE 297
 
Name Accession Description Interval E-value
murB PRK13905
UDP-N-acetylmuramate dehydrogenase;
4-301 5.43e-165

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 237553 [Multi-domain]  Cd Length: 298  Bit Score: 459.96  E-value: 5.43e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233   4 LVNELIKANVGRVLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRL 83
Cdd:PRK13905    1 LLKELLPALRGRLLENEPLARYTSFRVGGPADYLVEPADIEDLQEFLKLLKENNIPVTVLGNGSNLLVRDGGIRGVVIRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  84 GEGLDHLEVENHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEW 163
Cdd:PRK13905   81 GKGLNEIEVEGNRITAGAGAPLIKLARFAAEAGLSGLEFAAGIPGTVGGAVFMNAGAYGGETADVLESVEVLDRDGEIKT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 164 LMNSEMEFSYRTSVLQTKRpGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAG 243
Cdd:PRK13905  161 LSNEELGFGYRHSALQEEG-LIVLSATFQLEPGDKEEIKARMDELLARREATQPLEYPSAGSVFKNPPGHFAGKLIEEAG 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1208968233 244 LRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIGR 301
Cdd:PRK13905  240 LKGYRIGGAQVSEKHANFIINTGGATAADIEDLIEHVQKTVKEKFGVELEWEVRIIGE 297
MurB COG0812
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ...
 20-299 2.16e-133

UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440574 [Multi-domain]  Cd Length: 279  Bit Score: 379.36  E-value: 2.16e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  20 EPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGeGLDHLEV-ENHRVR 98
Cdd:COG0812     1 EPLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGLPVLVLGGGSNLLVRDDGFDGLVIRLG-RLKGIEVdDGVLVT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  99 VGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEWLMNSEMEFSYRTSVL 178
Cdd:COG0812    80 AGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLDRTGEVRTLSAEECGFGYRDSIF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 179 QTKRpGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISEMH 258
Cdd:COG0812   160 KRER-YIILSVTFRLKKGDPAEIAAVMDAVLAIRRSKQPLELPSAGSFFKNPPGDSAGWLIEQAGLKGYRIGGAQVSEKH 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1208968233 259 GNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEII 299
Cdd:COG0812   239 ANFLVNRGGATAADVLALIEEVQARVKEKFGVELEPEVRII 279
murB TIGR00179
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ...
 22-300 4.97e-119

UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 272945 [Multi-domain]  Cd Length: 284  Bit Score: 343.28  E-value: 4.97e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  22 LARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGEGLDHLEVENHRVRVGG 101
Cdd:TIGR00179   1 LAEFTTYKIGGNARHIVCPESIEQLVNVLDNAKEEDQPLLILGEGSNLLILDDGRGGVIINLGKGIDIEDDEGEYVHVGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 102 GYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEWLMNSEMEFSYRTSVLQTK 181
Cdd:TIGR00179  81 GENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATILLATGKTEWLTNEQLGFGYRTSIFQHK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 182 RPGIVLEAEFQLQVG-----EREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISE 256
Cdd:TIGR00179 161 YVGLVLKAEFQLTLGfgtrlDPETITAQQVFNKVCRMRTSHYPDPNAGSFFKNPSPNHAGRLIEECGLKGYQIGGAAVSK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1208968233 257 MHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:TIGR00179 241 QHANFLVNIDNAKSEDVLDLIEHVKAEVGEKYGILLEPEVKIIG 284
MurB_C pfam02873
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ...
 202-299 7.74e-49

UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.


Pssm-ID: 460730 [Multi-domain]  Cd Length: 99  Bit Score: 157.90  E-value: 7.74e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 202 IRN-MQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALI 280
Cdd:pfam02873   1 IRAaMLELRRRRLAKQPLDPPSAGSFFKNPVGHSAGWLIEQAGLKGYRIGGAQVSEKHANFLVNTGGATAADVLALIEEV 80

                          90
                  ....*....|....*....
gi 1208968233 281 KHTIKDKFGLDMHTEVEII 299
Cdd:pfam02873  81 RERVKEKFGVELEPEVRII 99
 
Name Accession Description Interval E-value
murB PRK13905
UDP-N-acetylmuramate dehydrogenase;
4-301 5.43e-165

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 237553 [Multi-domain]  Cd Length: 298  Bit Score: 459.96  E-value: 5.43e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233   4 LVNELIKANVGRVLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRL 83
Cdd:PRK13905    1 LLKELLPALRGRLLENEPLARYTSFRVGGPADYLVEPADIEDLQEFLKLLKENNIPVTVLGNGSNLLVRDGGIRGVVIRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  84 GEGLDHLEVENHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEW 163
Cdd:PRK13905   81 GKGLNEIEVEGNRITAGAGAPLIKLARFAAEAGLSGLEFAAGIPGTVGGAVFMNAGAYGGETADVLESVEVLDRDGEIKT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 164 LMNSEMEFSYRTSVLQTKRpGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAG 243
Cdd:PRK13905  161 LSNEELGFGYRHSALQEEG-LIVLSATFQLEPGDKEEIKARMDELLARREATQPLEYPSAGSVFKNPPGHFAGKLIEEAG 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1208968233 244 LRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIGR 301
Cdd:PRK13905  240 LKGYRIGGAQVSEKHANFIINTGGATAADIEDLIEHVQKTVKEKFGVELEWEVRIIGE 297
MurB COG0812
UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; ...
 20-299 2.16e-133

UDP-N-acetylenolpyruvoylglucosamine reductase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylenolpyruvoylglucosamine reductase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440574 [Multi-domain]  Cd Length: 279  Bit Score: 379.36  E-value: 2.16e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  20 EPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGeGLDHLEV-ENHRVR 98
Cdd:COG0812     1 EPLAPHTTFRIGGPADLLVEPASEEELAALLRAAREAGLPVLVLGGGSNLLVRDDGFDGLVIRLG-RLKGIEVdDGVLVT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  99 VGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEWLMNSEMEFSYRTSVL 178
Cdd:COG0812    80 AGAGENWHDLVRFALEAGLSGLEFLAGIPGTVGGAPVMNAGAYGGEIKDVLESVEVLDRTGEVRTLSAEECGFGYRDSIF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 179 QTKRpGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISEMH 258
Cdd:COG0812   160 KRER-YIILSVTFRLKKGDPAEIAAVMDAVLAIRRSKQPLELPSAGSFFKNPPGDSAGWLIEQAGLKGYRIGGAQVSEKH 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1208968233 259 GNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEII 299
Cdd:COG0812   239 ANFLVNRGGATAADVLALIEEVQARVKEKFGVELEPEVRII 279
murB TIGR00179
UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, ...
 22-300 4.97e-119

UDP-N-acetylenolpyruvoylglucosamine reductase; This model describes MurB, UDP-N-acetylenolpyruvoylglucosamine reductase, which is also called UDP-N-acetylmuramate dehydrogenase. It is part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide that is a precursor of bacterial peptidoglycan. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 272945 [Multi-domain]  Cd Length: 284  Bit Score: 343.28  E-value: 4.97e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  22 LARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGEGLDHLEVENHRVRVGG 101
Cdd:TIGR00179   1 LAEFTTYKIGGNARHIVCPESIEQLVNVLDNAKEEDQPLLILGEGSNLLILDDGRGGVIINLGKGIDIEDDEGEYVHVGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 102 GYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEWLMNSEMEFSYRTSVLQTK 181
Cdd:TIGR00179  81 GENWHKLVKYALKNGLSGLEFLAGIPGTVGGAVIMNAGAYGVEISEVLVYATILLATGKTEWLTNEQLGFGYRTSIFQHK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 182 RPGIVLEAEFQLQVG-----EREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISE 256
Cdd:TIGR00179 161 YVGLVLKAEFQLTLGfgtrlDPETITAQQVFNKVCRMRTSHYPDPNAGSFFKNPSPNHAGRLIEECGLKGYQIGGAAVSK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1208968233 257 MHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:TIGR00179 241 QHANFLVNIDNAKSEDVLDLIEHVKAEVGEKYGILLEPEVKIIG 284
PRK14649 PRK14649
UDP-N-acetylmuramate dehydrogenase;
15-300 1.09e-77

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 173112 [Multi-domain]  Cd Length: 295  Bit Score: 238.59  E-value: 1.09e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  15 RVLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRL-GEGLD-HLEV 92
Cdd:PRK14649    2 TLRENEPLAPYTSWRIGGPARYFVEPTTPDEAIAAAAWAEQRQLPLFWLGGGSNLLVRDEGFDGLVARYrGQRWElHEHG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  93 ENHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKA-LILFENGTIEWLMnSEMEF 171
Cdd:PRK14649   82 DTAEVWVEAGAPMAGTARRLAAQGWAGLEWAEGLPGTIGGAIYGNAGCYGGDTATVLIRAwLLLNGSECVEWSV-HDFAY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 172 SYRTSVLQ-------TKRPGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCaGSVFRNPLPDFAGHLVEKAGL 244
Cdd:PRK14649  161 GYRTSVLKqlradgiTWRPPLVLAARFRLHRDDPTALAARMEAIAAERKQKTPAGSSC-GSVFKNPPGDSAGRLIEAAGL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1208968233 245 RGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:PRK14649  240 KGTRIGDAEIATRHANYIINLGGARAADILRLIDLARTRVLAQFGIELELEVRIIG 295
murB PRK13906
UDP-N-acetylmuramate dehydrogenase;
18-300 7.20e-75

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 184386 [Multi-domain]  Cd Length: 307  Bit Score: 231.63  E-value: 7.20e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  18 VNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLgEGLDHLEVENHRV 97
Cdd:PRK13906   21 VDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISL-LSLDHIEVSDDAI 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  98 RVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEWLMNSEMEFSYRTSV 177
Cdd:PRK13906  100 IAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSI 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 178 LQtKRPGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISEM 257
Cdd:PRK13906  180 IQ-KEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTK 258

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1208968233 258 HGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:PRK13906  259 HAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIG 301
PRK14652 PRK14652
UDP-N-acetylmuramate dehydrogenase;
14-300 2.60e-74

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 237777 [Multi-domain]  Cd Length: 302  Bit Score: 230.14  E-value: 2.60e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  14 GRVLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGEGLDHLEVE 93
Cdd:PRK14652   16 GEVLRDAPLAPRTAVRVGGPADLLVRPADPDALSALLRAVRELGVPLSILGGGANTLVADAGVRGVVLRLPQDFPGESTD 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  94 NHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTiEWLMNSEMEFSY 173
Cdd:PRK14652   96 GGRLVLGAGAPISRLPARAHAHGLVGMEFLAGIPGTLGGAVAMNAGTKLGEMKDVVTAVELATADGA-GFVPAAALGYAY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 174 RTSVLQTKrpGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQ 253
Cdd:PRK14652  175 RTCRLPPG--AVITRVEVRLRPGDVAASEALMRADRERRRRTQPLDRPTFGSTFTNPPGDYAGRLVEAVGLKGHRVGGAI 252

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1208968233 254 ISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:PRK14652  253 WSPVHANFVTNLGGATARDVLALVRLARARVKERFGIALETEVRLLG 299
PRK14653 PRK14653
UDP-N-acetylmuramate dehydrogenase;
16-298 1.87e-71

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 237778 [Multi-domain]  Cd Length: 297  Bit Score: 222.79  E-value: 1.87e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  16 VLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKtKWTVIGRGSNLLVSDKGIEGVVIRLgEGLDHLEVENH 95
Cdd:PRK14653   16 VFINEEMKCHVSFKIGGPVPLFAIPNSTNGFIETINLLKEGI-EVKILGNGTNVLPKDEPMDFVVVST-ERLDDIFVDND 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  96 RVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKaLILFENGTIEWLMNSEMEFSYRT 175
Cdd:PRK14653   94 KIICESGLSLKKLCLVAAKNGLSGFENAYGIPGSVGGAVYMNAGAYGWETAENIVE-VVAYDGKKIIRLGKNEIKFSYRN 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 176 SVLQTKRPGIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRNPLPDF-AGHLVEKAGLRGYRIGGAQI 254
Cdd:PRK14653  173 SIFKEEKDLIILRVTFKLKKGNKNEIYNLMLETMKKRVEKQPLEFPSAGSVFKRPRKDFyVGSAIEKLGLKGFSIGGAQI 252

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1208968233 255 SEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEI 298
Cdd:PRK14653  253 SEKHAGFIINYNNAKAEDVLKLIEYVKDKIYENYNVELETEIEI 296
PRK12436 PRK12436
UDP-N-acetylmuramate dehydrogenase;
14-300 1.35e-70

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 171497 [Multi-domain]  Cd Length: 305  Bit Score: 220.65  E-value: 1.35e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  14 GRVLVNEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGEgLDHLEVE 93
Cdd:PRK12436   17 GHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIRGITVSLIH-ITGVTVT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  94 NHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENGTIEWLMNSEMEFSY 173
Cdd:PRK12436   96 GTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGDGELRTLTKEAFEFGY 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 174 RTSVLQTKRPgIVLEAEFQLQVGEREEIIRNMQkNKDYRRET-QPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGA 252
Cdd:PRK12436  176 RKSVFANNHY-IILEARFELEEGVYEEIKAKMD-DLTFKRESkQPLEYPSCGSVFKRPPNNFAGKLIQESGLQGKRIGGV 253

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1208968233 253 QISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:PRK12436  254 EVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIG 301
murB PRK13904
UDP-N-acetylmuramate dehydrogenase;
22-299 7.12e-63

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 184384 [Multi-domain]  Cd Length: 257  Bit Score: 199.38  E-value: 7.12e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  22 LARYTTMKIGGPADILIvpkhvtgIEKTlqlvKKYKTKWTVIGRGSNLLVSDK----GIegvvirLGEGLDHLEVENHRV 97
Cdd:PRK13904    7 FSKYSSVKIGPPLEVLV-------LEEI----DDFSQDGQIIGGANNLLISPNpknlAI------LGKNFDYIKIDGECL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  98 RVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFEngtieWLMNSEMEFSYRTSV 177
Cdd:PRK13904   70 EIGGATKSGKIFNYAKKNNLGGFEFLGKLPGTLGGLVKMNAGLKEYEISNNLESICTNGG-----WIEKEDIGFGYRSSG 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 178 LQtkrpGIVLEAEFQLQVGEREEI---IRNMQKNkdyrretQPwNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQI 254
Cdd:PRK13904  145 IN----GVILEARFKKTHGFDEELleaFKSMRKN-------QP-KGPSFGSCFKNPKGDYAGRLIEAVGLKGYCKGGAGF 212

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1208968233 255 SEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEII 299
Cdd:PRK13904  213 SEEHANFLVNLGGATFEDALDLIELAKKRVLEEFGINLEEEVIIL 257
PRK14651 PRK14651
UDP-N-acetylmuramate dehydrogenase;
21-300 4.06e-56

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 237776 [Multi-domain]  Cd Length: 273  Bit Score: 182.32  E-value: 4.06e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  21 PLARYTTMKIGGPADILIVPKHVtgiektlQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGEGLDHLEVENHrvrVG 100
Cdd:PRK14651    8 PLARYTTLGVGGPAELWTVETHE-------QLAEATEAPYRVLGGGSNLLVSDAGVPERVIRLGGEFAEWDLDGW---VG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 101 GGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILsKALILFENGTIEWLMNSEMEFSYRTSVLqt 180
Cdd:PRK14651   78 GGVPLPGLVRRAARLGLSGLEGLVGIPAQVGGAVKMNAGTRFGEMADAL-HTVEIVHDGGFHQYSPDELGFGYRHSGL-- 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 181 KRPGIVLEAEFQLQVGEREEIIRNMQKnKDYRRETQPWNHpCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISEMHGN 260
Cdd:PRK14651  155 PPGHVVTRVRLKLRPSTPEAVLAKMAL-VDAARKGQPKKK-SAGCAFKNPPGDSAGRLIDEAGLKGTRVGDAMISPEHGN 232

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1208968233 261 FIINTGGASAQDVLSLIALikhtIKDKFGLDMHTEVEIIG 300
Cdd:PRK14651  233 FIVNLGGATAADVHALLRR----VRARVGLPLELEWELWP 268
MurB_C pfam02873
UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are ...
 202-299 7.74e-49

UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Members of this family are UDP-N-acetylenolpyruvoylglucosamine reductase enzymes EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.


Pssm-ID: 460730 [Multi-domain]  Cd Length: 99  Bit Score: 157.90  E-value: 7.74e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 202 IRN-MQKNKDYRRETQPWNHPCAGSVFRNPLPDFAGHLVEKAGLRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALI 280
Cdd:pfam02873   1 IRAaMLELRRRRLAKQPLDPPSAGSFFKNPVGHSAGWLIEQAGLKGYRIGGAQVSEKHANFLVNTGGATAADVLALIEEV 80

                          90
                  ....*....|....*....
gi 1208968233 281 KHTIKDKFGLDMHTEVEII 299
Cdd:pfam02873  81 RERVKEKFGVELEPEVRII 99
PRK14650 PRK14650
UDP-N-acetylmuramate dehydrogenase;
1-300 5.60e-46

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 173113 [Multi-domain]  Cd Length: 302  Bit Score: 157.31  E-value: 5.60e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233   1 MEQLVNELIKANVGRVLVNepLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKG-IEGV 79
Cdd:PRK14650    2 LKNINNFLKKINIKPQTKN--LANYTTYKIGGISKLFLTPKTIKDAEHIFKAAIEEKIKIFILGGGSNILINDEEeIDFP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  80 VIRLGEgLDHLEVENHRVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALILFENG 159
Cdd:PRK14650   80 IIYTGH-LNKIEIHDNQIVAECGTNFEDLCKFALQNELSGLEFIYGLPGTLGGAIWMNARCFGNEISEILDKITFIDEKG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 160 TIEWLMNSEMEFSYRTSVLQTKRPgIVLEAEFQLQVGEREEIIRNMQKNKDYRRETQPWNHPCAGSVFRN--PLPDFAGH 237
Cdd:PRK14650  159 KTICKKFKKEEFKYKISPFQNKNT-FILKATLNLKKGNKKHIEEIMKQNKQIRINKGHYLFPSSGSTFKNnkAFLKPTGQ 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1208968233 238 LVEKAGLRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFGLDMHTEVEIIG 300
Cdd:PRK14650  238 IIEECKLKGLSIGGATVSHYHGNFIININNATSKDIKTLIEKVKTEVQIKTGFLLEEEVLYIG 300
murB PRK13903
UDP-N-acetylmuramate dehydrogenase;
21-300 2.00e-44

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 237552 [Multi-domain]  Cd Length: 363  Bit Score: 154.73  E-value: 2.00e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  21 PLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLG-EGLDhLEVENHRVRV 99
Cdd:PRK13903   20 PLAPLTTLRVGGPARRLVTCTSTEELVAAVRELDAAGEPLLVLGGGSNLVIADDGFDGTVVRVAtRGVT-VDCGGGLVRA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 100 GGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALIL-FENGTIEWLMNSEMEFSYRTSVL 178
Cdd:PRK13903   99 EAGAVWDDVVARTVEAGLGGLECLSGIPGSAGATPVQNVGAYGQEVSDTITRVRLLdRRTGEVRWVPAADLGFGYRTSVL 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 179 QTKRPGIVLEAEFQLQVGERE------EIIRNMQKNKDYR------RET------------QPWNHPC--AGSVFRNPL- 231
Cdd:PRK13903  179 KHSDRAVVLEVEFQLDPSGLSaplrygELARALGVEPGERvppaavREAvlalragkgmvlDPADHDTwsAGSFFTNPVv 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 232 --------------------PDF----------AGHLVEKAGL-RGYRIGG--AQISEMHGNFIINTGGASAQDVLSLIA 278
Cdd:PRK13903  259 spavaerlaarvaerlgdpvPRYpagdggvklsAAWLIERAGFgKGYPGGGapARLSTKHTLALTNRGGATTADLVALAR 338

                         330       340
                  ....*....|....*....|..
gi 1208968233 279 LIKHTIKDKFGLDMHTEVEIIG 300
Cdd:PRK13903  339 EVRDGVRDAFGVTLVPEPVLVG 360
PRK14648 PRK14648
UDP-N-acetylmuramate dehydrogenase;
19-296 2.01e-33

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 173111 [Multi-domain]  Cd Length: 354  Bit Score: 125.61  E-value: 2.01e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  19 NEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGEgLDHLEVENHR-- 96
Cdd:PRK14648   15 NVPLAERCSFRIGGAAQFWAEPRSCTQLRALIEEAQRARIPLSLIGGGSNVLIADEGVPGLMLSLRR-FRSLHTQTQRdg 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  97 ---VRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSILSKALIL------------------ 155
Cdd:PRK14648   94 svlVHAGAGLPVAALLAFCAHHALRGLETFAGLPGSVGGAAYMNARCYGRAIADCFHSARTLvlhpvrsrakelpevrkn 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 156 ---------------FENGTIEWLMNSEMEFSYRTSVLQTKRpGIVLEAE--------FQLQVGEREEIIRNMQKNKDYR 212
Cdd:PRK14648  174 aqdkrgeclgldggpFTCSSFQTVFARAGDWGYKRSPFQSPH-GVELHAGrrlilslcVRLTPGNPAQIRKHMQEKIADR 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 213 RETQPWNHPCAGSVFRNPlPDF---AGHLVEKAGLRGYRIGGAQISEMHGNFIINTGGASAQDVLSLIALIKHTIKDKFG 289
Cdd:PRK14648  253 ISKGQFRFPSAGSAFKNN-PAFgkpSGILIEEAGLRGTSCGAAQVAPWHGNLIINTGNATAHQVRTLLRVVRQRVFETHG 331


                  ....*..
gi 1208968233 290 LDMHTEV 296
Cdd:PRK14648  332 VWLEREI 338
murB PRK00046
UDP-N-acetylmuramate dehydrogenase;
19-299 1.28e-26

UDP-N-acetylmuramate dehydrogenase;


Pssm-ID: 234593 [Multi-domain]  Cd Length: 334  Bit Score: 106.77  E-value: 1.28e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  19 NEPLARYTTMKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKgIEGVVIRLG-EGLDHLEV--ENH 95
Cdd:PRK00046    6 NHSLKPLNTFGIDARARHLVEAESEEQLLEALADARAAGLPVLVLGGGSNVLFTED-FDGTVLLNRiKGIEVLSEddDAW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  96 RVRVGGG---YPLIKLSTllsRQGLAGLEFASGIPGSVGGAVYMNAGAH----KSDISSIlsKALILfENGTIEWLMNSE 168
Cdd:PRK00046   85 YLHVGAGenwHDLVLWTL---QQGMPGLENLALIPGTVGAAPIQNIGAYgvelKDVCDYV--EALDL-ATGEFVRLSAAE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 169 MEFSYRTSVLQTKRPG--IVLEAEFQLQvgereeiiRNMQKNKDY---RRETQ----------------------PWNHP 221
Cdd:PRK00046  159 CRFGYRDSIFKHEYPDryAITAVGFRLP--------KQWQPVLDYgdlARLDPdtvtaqdvfdavcairrsklpdPKVLG 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233 222 CAGSVFRNPL-------------PDF-------------AGHLVEKAGLRGYRIGGAQISEMHGNFIINTGGASAQDVLS 275
Cdd:PRK00046  231 NAGSFFKNPVvsaeqfeallaqyPDIphypqadgsvklaAGWLIDQCGLKGFQIGGAAVHEKQALVLVNYGNATGADVLA 310

                         330       340
                  ....*....|....*....|....
gi 1208968233 276 LIALIKHTIKDKFGLDMHTEVEII 299
Cdd:PRK00046  311 LARHIQQDVREKFGVELEPEPRFI 334
FAD_binding_4 pfam01565
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most ...
 34-164 1.44e-20

FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.


Pssm-ID: 426326 [Multi-domain]  Cd Length: 139  Bit Score: 85.72  E-value: 1.44e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233  34 ADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNLLVSDKGIEGVVIRLGE--GLDHLEVENHRVRVGGGYPLIKLSTL 111
Cdd:pfam01565   1 PAAVVLPESEEEVAAIVRLANENGLPVLPRGGGSSLLGGAVQTGGIVLDLSRlnGILEIDPEDGTATVEAGVTLGDLVRA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1208968233 112 LSRQGLA-GLEFASGIPGSVGGAVYMNAGAHKS----DISSILSKALILFENGTIEWL 164
Cdd:pfam01565  81 LAAKGLLlGLDPGSGIPGTVGGAIATNAGGYGSekygLTRDNVLGLEVVLADGEVVRL 138
GlcD COG0277
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];
1-139 8.09e-05

FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];


Pssm-ID: 440046 [Multi-domain]  Cd Length: 462  Bit Score: 43.73  E-value: 8.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208968233   1 MEQLVNELIKANVGRVLVNEP-LARYTT---MKIGGPADILIVPKHVTGIEKTLQLVKKYKTKWTVIGRGSNL---LVSD 73
Cdd:COG0277     3 TAALLAALRAILAGRVLTDPAdRAAYARdgnSLYRGRPDAVVRPRSTEDVAAVVRLAAEHGVPVVPRGGGTGLaggAVPL 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1208968233  74 KGieGVVIRLGE--GLDHLEVENHRVRVGGGYPLIKLSTLLSRQGLA-GLEFASGIPGSVGGAVYMNAG 139
Cdd:COG0277    83 DG--GVVLDLSRmnRILEVDPEDRTATVEAGVTLADLNAALAPHGLFfPPDPSSQGTATIGGNIATNAG 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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