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glutathione synthase [Vibrio splendidus]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
GSH_synth_ATP super family
cl46478 Eukaryotic glutathione synthase, ATP binding domain;
8-481
3.52e-96
Eukaryotic glutathione synthase, ATP binding domain;
pfam03917 :Pssm-ID: 461091
Cd Length: 465
Bit Score: 298.26
E-value: 3.52e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ L I E D A CE WA IM HG VAF R ---- Q S DNT A R H C PF SIA P MTME R EVY E HLLK V T P LITK L ISN V SE D HD FL QSS L SDMA K A 83
Cdd:pfam03917 5 EE L V E N A KD WA LA HG LLM R pked P S GVL A T H A PF TLF P SPFP R KLF E QAVA V Q P AYNE L YAR V AQ D EE FL EEI L EEVI K V 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 84 D P F FGR L M E LHQQAHG E V syrlyp AR QP -- L L L M R T D F M DDRQH G A ---- K VI EFN G I AAGMAPFGQRAT E F H SFMQNQ w 157
Cdd:pfam03917 85 D D F TAK L W E IYEKVKE E G ------ IV QP is L G L F R S D Y M LHQDE G S spsl K QV EFN T I SSSFGGLSSKVS E L H RYLLSR - 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 158 PNV Y N D W L E D PSAT P a EN QG L MQ LA Y G I A N A ARQVK S dfkeq D K P V F L M VVQ KN E D N VY DQ HL LE V EL - QKQ G V R TV RRT 236
Cdd:pfam03917 158 LGA Y P D S L L D DENL P - EN NS L SG LA E G L A K A WKAYG S ----- P K A V V L F VVQ PG E R N IF DQ RH LE Y EL w ENH G I R VI RRT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 237 FEQLSCQLSSG D NQ R L L LK D VGA V D VVY L RAGY QY SDY ----- W apelnesvcchtls QT RL FM E QHH v A MNA - T I SQ QL 310
Cdd:pfam03917 232 LTEILEETKLD D PD R T L FV D GQE V S VVY F RAGY AP SDY pseke W -------------- DA RL LL E RSR - A IKC p S I LT QL 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 311 A TS K TM Q ML L TMMPAA E ya R WGLTR EEA ELVKSVL A ----- D MKPITSKSIEWFNTQAD K qe W VLK N Q G EGGG HCVF G D D 385
Cdd:pfam03917 297 A GT K KV Q QV L ATPGVL E -- R FLPDE EEA ARLRETF A glypl D DSEEGLEAVKLALENPE K -- Y VLK P Q R EGGG NNIY G E D 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 386 I S E Q L SQ L KP EE YD A WA LM QRLY P HE rd V PTMA VR D t QQTLVTDLV SE V G LFTAY - YK G EPVT E L g GY AG Y L I R S K PA S E 464
Cdd:pfam03917 373 I P E F L KS L PE EE WS A YI LM ELIE P PP -- V KNYL VR N - GEVVKGEVI SE L G IYGTI l WG G DEIL E N - EQ AG H L L R T K GS S S 448
490
....*....|....*..
gi 1215145487 465 NEGG IHS G K G I LDS LT L 481
Cdd:pfam03917 449 NEGG VAA G F G V LDS PY L 465
Name
Accession
Description
Interval
E-value
GSH_synth_ATP
pfam03917 Eukaryotic glutathione synthase, ATP binding domain;
8-481
3.52e-96
Eukaryotic glutathione synthase, ATP binding domain;
Pssm-ID: 461091
Cd Length: 465
Bit Score: 298.26
E-value: 3.52e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ L I E D A CE WA IM HG VAF R ---- Q S DNT A R H C PF SIA P MTME R EVY E HLLK V T P LITK L ISN V SE D HD FL QSS L SDMA K A 83
Cdd:pfam03917 5 EE L V E N A KD WA LA HG LLM R pked P S GVL A T H A PF TLF P SPFP R KLF E QAVA V Q P AYNE L YAR V AQ D EE FL EEI L EEVI K V 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 84 D P F FGR L M E LHQQAHG E V syrlyp AR QP -- L L L M R T D F M DDRQH G A ---- K VI EFN G I AAGMAPFGQRAT E F H SFMQNQ w 157
Cdd:pfam03917 85 D D F TAK L W E IYEKVKE E G ------ IV QP is L G L F R S D Y M LHQDE G S spsl K QV EFN T I SSSFGGLSSKVS E L H RYLLSR - 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 158 PNV Y N D W L E D PSAT P a EN QG L MQ LA Y G I A N A ARQVK S dfkeq D K P V F L M VVQ KN E D N VY DQ HL LE V EL - QKQ G V R TV RRT 236
Cdd:pfam03917 158 LGA Y P D S L L D DENL P - EN NS L SG LA E G L A K A WKAYG S ----- P K A V V L F VVQ PG E R N IF DQ RH LE Y EL w ENH G I R VI RRT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 237 FEQLSCQLSSG D NQ R L L LK D VGA V D VVY L RAGY QY SDY ----- W apelnesvcchtls QT RL FM E QHH v A MNA - T I SQ QL 310
Cdd:pfam03917 232 LTEILEETKLD D PD R T L FV D GQE V S VVY F RAGY AP SDY pseke W -------------- DA RL LL E RSR - A IKC p S I LT QL 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 311 A TS K TM Q ML L TMMPAA E ya R WGLTR EEA ELVKSVL A ----- D MKPITSKSIEWFNTQAD K qe W VLK N Q G EGGG HCVF G D D 385
Cdd:pfam03917 297 A GT K KV Q QV L ATPGVL E -- R FLPDE EEA ARLRETF A glypl D DSEEGLEAVKLALENPE K -- Y VLK P Q R EGGG NNIY G E D 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 386 I S E Q L SQ L KP EE YD A WA LM QRLY P HE rd V PTMA VR D t QQTLVTDLV SE V G LFTAY - YK G EPVT E L g GY AG Y L I R S K PA S E 464
Cdd:pfam03917 373 I P E F L KS L PE EE WS A YI LM ELIE P PP -- V KNYL VR N - GEVVKGEVI SE L G IYGTI l WG G DEIL E N - EQ AG H L L R T K GS S S 448
490
....*....|....*..
gi 1215145487 465 NEGG IHS G K G I LDS LT L 481
Cdd:pfam03917 449 NEGG VAA G F G V LDS PY L 465
eu-GS
cd00228 Eukaryotic Glutathione Synthetase (eu-GS); catalyses the production of glutathione from ...
8-482
2.75e-79
Eukaryotic Glutathione Synthetase (eu-GS); catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Belongs to the ATP-grasp superfamily.
Pssm-ID: 238140
Cd Length: 471
Bit Score: 254.60
E-value: 2.75e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ L IE DA CE WA IMH G VAF R ----- Q S DNT A R H C PF SIA P MTMEREVY E HLLK V T P LITK L ISNV S E D HD FLQ S SLS DMA K 82
Cdd:cd00228 11 EE L AK DA ND WA VAN G LVM R dksvq E S SVV A S H A PF TLL P SPFPEALF E QAVE V Q P DFNE L VDRI S Q D GK FLQ Q SLS STK K 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 83 A D P F FG RL MEL H QQAHG E vs YRLY P A R qp L LLM R T D F M D D RQH G A --- K V IE F N G I AAGMAPFGQ R A TE F H SFMQNQ wpn 159
Cdd:cd00228 91 V D E F TS RL LDI H KKVLE E -- NKKQ P V R -- L GIF R S D Y M F D EKD G T kgl K Q IE I N T I SSSFGGLSS R V TE L H RYVLSA --- 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 160 v YNDWL - E D PSAT P AE N QG l MQL A YGI A N A A rqvk SDFKEQD k P V F L M VVQ KN E D N V YDQ HL LE V EL - QKQGVRTV R R T F 237
Cdd:cd00228 164 - LGYSK g L D SNRI P SN N AV - KGI A EAL A K A W ---- EEYGDPR - A V V L F VVQ NE E R N I YDQ RF LE A EL l ERHQIHVI R K T L 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 238 EQLSCQL S SG D NQR L LLKDV g A V D VVY L RAGY QYS DY wa P ELN E svcchtl SQT RL F ME QHHVAMNAT IS Q QLA TS K TM Q 317
Cdd:cd00228 237 ADVDEEG S LD D DGT L FVDGQ - E V A VVY F RAGY TPD DY -- P SES E ------- WEA RL L ME RSSAIKCPS IS T QLA GT K KI Q 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 318 ML L TMMPAA E ya R WGLTR EE AELVKSVL A DMKP --------- I TS K SI E wfntqa DKQEW VLK N Q G EGGG HCVF G DDIS E 388
Cdd:cd00228 307 QE L AEPGVL E -- R FLPNP EE VAKLRATF A GLYS lddteegde I VR K AL E ------ KPELF VLK P Q R EGGG NNIY G EEMR E 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 389 Q L SQ L KP - EE YD A WA LM QRLY P he RDVPTMAV R DTQQTLVTDLV SE V G LFTA Y YKGEPVTELGGYA G Y L I R S KP A S EN EG 467
Cdd:cd00228 379 A L LK L QG s EE RA A YI LM EKIF P -- EPSENYLL R AGGPSHKEQAI SE L G IYGT Y LRNKDEVVMNKQS G H L L R T KP I S SA EG 456
490
....*....|....*
gi 1215145487 468 G IHS G KGI LDS LT L I 482
Cdd:cd00228 457 G VAA G FAV LDS IY L V 471
glut_syn_euk
TIGR01986 glutathione synthetase, eukaryotic; This model represents the eukaryotic glutathione ...
8-481
1.24e-78
glutathione synthetase, eukaryotic; This model represents the eukaryotic glutathione synthetase, which shows little resemblance to the analogous enzyme of Gram-negative bacteria (TIGR01380). In the Kinetoplastida, trypanothione replaces glutathione, but can be made from glutathione; a sequence from Leishmania is not included in the seed, is highly divergent, and therefore scores between the trusted and noise cutoffs.
Pssm-ID: 273912
Cd Length: 472
Bit Score: 252.83
E-value: 1.24e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ LI ED A CE WAI M HGV AFR ------ QSDNT A RHC P FSIA P MTME R EVYEHLLK V T P LITK L ISNV S E D HD FL QSS LS DM A 81
Cdd:TIGR01986 2 EE LI QE A ND WAI A HGV VMY ppsfek EGPVN A SVA P ITLF P SPIP R ACFDEAVQ V Q P VFNE L YARI S Q D MA FL HKT LS ST A 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 82 K A D P F F G R L ME L HQQAHGEVS Y RLYPA R qp L L L M R T D F M D D RQH G A --- K VI EFN G I AAGMAPFGQRATEF HS FMQ nqwp 158
Cdd:TIGR01986 82 K S D E F T G K L WD L YLKTLKSAQ Y KKQNF R -- L G L F R S D Y M I D KKD G T eql K QV EFN T I SVSFGGLSEKVSRL HS YLL ---- 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 159 NVYNDWLED P SATPAE N QGLMQ LA Y GIA N A ARQV KS DFKE -- QDK P VF L MV VQ K NE D N VY DQ HL LE V EL - QKQGVRTV R R 235
Cdd:TIGR01986 156 RSNKYDPKG P IYNMVI N TSGYG LA K GIA K A VESY KS PQSS st TSD P IV L FI VQ R NE R N IF DQ RV LE L EL l ERFNIKSI R L 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 236 TF EQLSCQ LS - SG D NQR L LLK D V G - AVD VVY L R A GY QYS DY WAPELN E S vcchtlsqt RL FM E QHHVAMNAT I SQ QLA T S 313
Cdd:TIGR01986 236 TF ADVNDK LS i DD D TGK L FVR D T G q EIA VVY Y R T GY TPT DY PSQKDW E A --------- RL LL E KSFAIKCPD I AT QLA G S 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 314 K TM Q ML L TMMPAA E ya R WGLTR E EAELVKSVL A DMK P I -- T SKSI E WFNTQAD K QE - W VLK N Q G EGGG HC V F G D DI SEQ L 390
Cdd:TIGR01986 307 K KI Q QE L ADPGVL E -- R FLSDA E KKASLRKTF A GLY P L dd T KLGR E GIKLALE K PS k F VLK P Q R EGGG NN V Y G E DI PNF L 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 391 SQ L KP EE Y D AWA LM QRLY P her DVPTMAVRDTQQTLVTDLV SE V G LFTA Y YKGEPVTELGGYA G Y L I R S K PASE NEGG IH 470
Cdd:TIGR01986 385 KG L EE EE W D SYI LM ELIE P --- EPSENIILRDGKSYKEQII SE L G IYGC Y VRNDKTVVSNEQS G S L L R T K FNTS NEGG VA 461
490
....*....|.
gi 1215145487 471 S G KGI LDS LT L 481
Cdd:TIGR01986 462 A G FAV LDS IY L 472
PLN02977
PLN02977 glutathione synthetase
2-482
1.82e-77
glutathione synthetase
Pssm-ID: 215528
Cd Length: 478
Bit Score: 249.97
E-value: 1.82e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 2 LT SLIP Q Q L I E D A CE W AIM HG -- V AF R QSDNTAR ------- H C P F S IA P MTME R EVYEHLLKVT PL ITK L ISN VS E D HD F 72
Cdd:PLN02977 10 LT KELL Q D L V E E A LV W SSL HG lv V GD R SDQRSGT vpgvglv H A P I S LL P TPFP R AAFKQACELA PL FNE L VDR VS R D GE F 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 73 LQ SS L SDMA K A D P F FG RL MEL H QQAHGEVSYR ly PA R qp L L L M R T D F M D D RQH G A - KVI E F N G I AAGMAPFGQRATEF H S 151
Cdd:PLN02977 90 LQ ET L ARTR K V D E F TS RL LDI H EKMGERNKRE -- DI R -- L G L H R S D Y M L D EPT G L l LQV E L N T I SSSFPGLSSLVSQL H R 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 152 FMQNQ wpnv Y NDW L E - DP SAT P a EN QG L M Q L A YGI A N A ARQV ksdfk EQDKP V F LMVVQ KN E D N V YDQ HL L EVE L - QKQ G 229
Cdd:PLN02977 166 SLLSR ---- Y GRV L G l DP ERV P - EN PA L E Q F A DAL A A A WKEF ----- GNPSA V V LMVVQ PE E R N M YDQ RW L SFA L w ERH G 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 230 V RT V R R T FEQLSCQL S SGDNQR L LLKDV g A V D VVY L RAGY QYS DY ----- W apelnesvcchtls QT RL FM E QHHVAMNA 304
Cdd:PLN02977 236 I RT I R K T LAEIAAEG S LDEDGT L TVDGQ - P V A VVY F RAGY APT DY pseae W -------------- RA RL LL E RSSAVKCP 300
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 305 T I SQQ LA TS K TM Q ML L TMMPAA E ya R WGLTR E EAELVKSVL A DMKPITSKSIEWFNTQ A DKQE -- W VLK N Q G EGGG HCVF 382
Cdd:PLN02977 301 S I AYH LA GT K KV Q QE L AKPGVL E -- R FLDDK E DIAKLRKCF A GLWSLDDEAAAEIVKL A IEKP el F VLK P Q R EGGG NNIY 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 383 GDD IS E Q L SQ L KP E EYD --- A WA LMQR LY P he RDVP T MA VR DTQ - QTLV T dl V SE V G LFT AY YK - G EP V T e LGGYA GYL I 457
Cdd:PLN02977 379 GDD LR E T L ER L QK E GGE dla A YI LMQR IF P -- PVSR T YL VR NGV c EEGE T -- I SE L G IYG AY LR n G DK V I - INEQS GYL L 453
490 500
....*....|....*....|....*
gi 1215145487 458 R S K P AS EN EGG IHS G KGI LDS LT L I 482
Cdd:PLN02977 454 R T K A AS SD EGG VAA G FAV LDS PY L T 478
Name
Accession
Description
Interval
E-value
GSH_synth_ATP
pfam03917 Eukaryotic glutathione synthase, ATP binding domain;
8-481
3.52e-96
Eukaryotic glutathione synthase, ATP binding domain;
Pssm-ID: 461091
Cd Length: 465
Bit Score: 298.26
E-value: 3.52e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ L I E D A CE WA IM HG VAF R ---- Q S DNT A R H C PF SIA P MTME R EVY E HLLK V T P LITK L ISN V SE D HD FL QSS L SDMA K A 83
Cdd:pfam03917 5 EE L V E N A KD WA LA HG LLM R pked P S GVL A T H A PF TLF P SPFP R KLF E QAVA V Q P AYNE L YAR V AQ D EE FL EEI L EEVI K V 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 84 D P F FGR L M E LHQQAHG E V syrlyp AR QP -- L L L M R T D F M DDRQH G A ---- K VI EFN G I AAGMAPFGQRAT E F H SFMQNQ w 157
Cdd:pfam03917 85 D D F TAK L W E IYEKVKE E G ------ IV QP is L G L F R S D Y M LHQDE G S spsl K QV EFN T I SSSFGGLSSKVS E L H RYLLSR - 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 158 PNV Y N D W L E D PSAT P a EN QG L MQ LA Y G I A N A ARQVK S dfkeq D K P V F L M VVQ KN E D N VY DQ HL LE V EL - QKQ G V R TV RRT 236
Cdd:pfam03917 158 LGA Y P D S L L D DENL P - EN NS L SG LA E G L A K A WKAYG S ----- P K A V V L F VVQ PG E R N IF DQ RH LE Y EL w ENH G I R VI RRT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 237 FEQLSCQLSSG D NQ R L L LK D VGA V D VVY L RAGY QY SDY ----- W apelnesvcchtls QT RL FM E QHH v A MNA - T I SQ QL 310
Cdd:pfam03917 232 LTEILEETKLD D PD R T L FV D GQE V S VVY F RAGY AP SDY pseke W -------------- DA RL LL E RSR - A IKC p S I LT QL 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 311 A TS K TM Q ML L TMMPAA E ya R WGLTR EEA ELVKSVL A ----- D MKPITSKSIEWFNTQAD K qe W VLK N Q G EGGG HCVF G D D 385
Cdd:pfam03917 297 A GT K KV Q QV L ATPGVL E -- R FLPDE EEA ARLRETF A glypl D DSEEGLEAVKLALENPE K -- Y VLK P Q R EGGG NNIY G E D 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 386 I S E Q L SQ L KP EE YD A WA LM QRLY P HE rd V PTMA VR D t QQTLVTDLV SE V G LFTAY - YK G EPVT E L g GY AG Y L I R S K PA S E 464
Cdd:pfam03917 373 I P E F L KS L PE EE WS A YI LM ELIE P PP -- V KNYL VR N - GEVVKGEVI SE L G IYGTI l WG G DEIL E N - EQ AG H L L R T K GS S S 448
490
....*....|....*..
gi 1215145487 465 NEGG IHS G K G I LDS LT L 481
Cdd:pfam03917 449 NEGG VAA G F G V LDS PY L 465
eu-GS
cd00228 Eukaryotic Glutathione Synthetase (eu-GS); catalyses the production of glutathione from ...
8-482
2.75e-79
Eukaryotic Glutathione Synthetase (eu-GS); catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Belongs to the ATP-grasp superfamily.
Pssm-ID: 238140
Cd Length: 471
Bit Score: 254.60
E-value: 2.75e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ L IE DA CE WA IMH G VAF R ----- Q S DNT A R H C PF SIA P MTMEREVY E HLLK V T P LITK L ISNV S E D HD FLQ S SLS DMA K 82
Cdd:cd00228 11 EE L AK DA ND WA VAN G LVM R dksvq E S SVV A S H A PF TLL P SPFPEALF E QAVE V Q P DFNE L VDRI S Q D GK FLQ Q SLS STK K 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 83 A D P F FG RL MEL H QQAHG E vs YRLY P A R qp L LLM R T D F M D D RQH G A --- K V IE F N G I AAGMAPFGQ R A TE F H SFMQNQ wpn 159
Cdd:cd00228 91 V D E F TS RL LDI H KKVLE E -- NKKQ P V R -- L GIF R S D Y M F D EKD G T kgl K Q IE I N T I SSSFGGLSS R V TE L H RYVLSA --- 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 160 v YNDWL - E D PSAT P AE N QG l MQL A YGI A N A A rqvk SDFKEQD k P V F L M VVQ KN E D N V YDQ HL LE V EL - QKQGVRTV R R T F 237
Cdd:cd00228 164 - LGYSK g L D SNRI P SN N AV - KGI A EAL A K A W ---- EEYGDPR - A V V L F VVQ NE E R N I YDQ RF LE A EL l ERHQIHVI R K T L 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 238 EQLSCQL S SG D NQR L LLKDV g A V D VVY L RAGY QYS DY wa P ELN E svcchtl SQT RL F ME QHHVAMNAT IS Q QLA TS K TM Q 317
Cdd:cd00228 237 ADVDEEG S LD D DGT L FVDGQ - E V A VVY F RAGY TPD DY -- P SES E ------- WEA RL L ME RSSAIKCPS IS T QLA GT K KI Q 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 318 ML L TMMPAA E ya R WGLTR EE AELVKSVL A DMKP --------- I TS K SI E wfntqa DKQEW VLK N Q G EGGG HCVF G DDIS E 388
Cdd:cd00228 307 QE L AEPGVL E -- R FLPNP EE VAKLRATF A GLYS lddteegde I VR K AL E ------ KPELF VLK P Q R EGGG NNIY G EEMR E 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 389 Q L SQ L KP - EE YD A WA LM QRLY P he RDVPTMAV R DTQQTLVTDLV SE V G LFTA Y YKGEPVTELGGYA G Y L I R S KP A S EN EG 467
Cdd:cd00228 379 A L LK L QG s EE RA A YI LM EKIF P -- EPSENYLL R AGGPSHKEQAI SE L G IYGT Y LRNKDEVVMNKQS G H L L R T KP I S SA EG 456
490
....*....|....*
gi 1215145487 468 G IHS G KGI LDS LT L I 482
Cdd:cd00228 457 G VAA G FAV LDS IY L V 471
glut_syn_euk
TIGR01986 glutathione synthetase, eukaryotic; This model represents the eukaryotic glutathione ...
8-481
1.24e-78
glutathione synthetase, eukaryotic; This model represents the eukaryotic glutathione synthetase, which shows little resemblance to the analogous enzyme of Gram-negative bacteria (TIGR01380). In the Kinetoplastida, trypanothione replaces glutathione, but can be made from glutathione; a sequence from Leishmania is not included in the seed, is highly divergent, and therefore scores between the trusted and noise cutoffs.
Pssm-ID: 273912
Cd Length: 472
Bit Score: 252.83
E-value: 1.24e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 8 QQ LI ED A CE WAI M HGV AFR ------ QSDNT A RHC P FSIA P MTME R EVYEHLLK V T P LITK L ISNV S E D HD FL QSS LS DM A 81
Cdd:TIGR01986 2 EE LI QE A ND WAI A HGV VMY ppsfek EGPVN A SVA P ITLF P SPIP R ACFDEAVQ V Q P VFNE L YARI S Q D MA FL HKT LS ST A 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 82 K A D P F F G R L ME L HQQAHGEVS Y RLYPA R qp L L L M R T D F M D D RQH G A --- K VI EFN G I AAGMAPFGQRATEF HS FMQ nqwp 158
Cdd:TIGR01986 82 K S D E F T G K L WD L YLKTLKSAQ Y KKQNF R -- L G L F R S D Y M I D KKD G T eql K QV EFN T I SVSFGGLSEKVSRL HS YLL ---- 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 159 NVYNDWLED P SATPAE N QGLMQ LA Y GIA N A ARQV KS DFKE -- QDK P VF L MV VQ K NE D N VY DQ HL LE V EL - QKQGVRTV R R 235
Cdd:TIGR01986 156 RSNKYDPKG P IYNMVI N TSGYG LA K GIA K A VESY KS PQSS st TSD P IV L FI VQ R NE R N IF DQ RV LE L EL l ERFNIKSI R L 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 236 TF EQLSCQ LS - SG D NQR L LLK D V G - AVD VVY L R A GY QYS DY WAPELN E S vcchtlsqt RL FM E QHHVAMNAT I SQ QLA T S 313
Cdd:TIGR01986 236 TF ADVNDK LS i DD D TGK L FVR D T G q EIA VVY Y R T GY TPT DY PSQKDW E A --------- RL LL E KSFAIKCPD I AT QLA G S 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 314 K TM Q ML L TMMPAA E ya R WGLTR E EAELVKSVL A DMK P I -- T SKSI E WFNTQAD K QE - W VLK N Q G EGGG HC V F G D DI SEQ L 390
Cdd:TIGR01986 307 K KI Q QE L ADPGVL E -- R FLSDA E KKASLRKTF A GLY P L dd T KLGR E GIKLALE K PS k F VLK P Q R EGGG NN V Y G E DI PNF L 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 391 SQ L KP EE Y D AWA LM QRLY P her DVPTMAVRDTQQTLVTDLV SE V G LFTA Y YKGEPVTELGGYA G Y L I R S K PASE NEGG IH 470
Cdd:TIGR01986 385 KG L EE EE W D SYI LM ELIE P --- EPSENIILRDGKSYKEQII SE L G IYGC Y VRNDKTVVSNEQS G S L L R T K FNTS NEGG VA 461
490
....*....|.
gi 1215145487 471 S G KGI LDS LT L 481
Cdd:TIGR01986 462 A G FAV LDS IY L 472
PLN02977
PLN02977 glutathione synthetase
2-482
1.82e-77
glutathione synthetase
Pssm-ID: 215528
Cd Length: 478
Bit Score: 249.97
E-value: 1.82e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 2 LT SLIP Q Q L I E D A CE W AIM HG -- V AF R QSDNTAR ------- H C P F S IA P MTME R EVYEHLLKVT PL ITK L ISN VS E D HD F 72
Cdd:PLN02977 10 LT KELL Q D L V E E A LV W SSL HG lv V GD R SDQRSGT vpgvglv H A P I S LL P TPFP R AAFKQACELA PL FNE L VDR VS R D GE F 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 73 LQ SS L SDMA K A D P F FG RL MEL H QQAHGEVSYR ly PA R qp L L L M R T D F M D D RQH G A - KVI E F N G I AAGMAPFGQRATEF H S 151
Cdd:PLN02977 90 LQ ET L ARTR K V D E F TS RL LDI H EKMGERNKRE -- DI R -- L G L H R S D Y M L D EPT G L l LQV E L N T I SSSFPGLSSLVSQL H R 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 152 FMQNQ wpnv Y NDW L E - DP SAT P a EN QG L M Q L A YGI A N A ARQV ksdfk EQDKP V F LMVVQ KN E D N V YDQ HL L EVE L - QKQ G 229
Cdd:PLN02977 166 SLLSR ---- Y GRV L G l DP ERV P - EN PA L E Q F A DAL A A A WKEF ----- GNPSA V V LMVVQ PE E R N M YDQ RW L SFA L w ERH G 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 230 V RT V R R T FEQLSCQL S SGDNQR L LLKDV g A V D VVY L RAGY QYS DY ----- W apelnesvcchtls QT RL FM E QHHVAMNA 304
Cdd:PLN02977 236 I RT I R K T LAEIAAEG S LDEDGT L TVDGQ - P V A VVY F RAGY APT DY pseae W -------------- RA RL LL E RSSAVKCP 300
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 305 T I SQQ LA TS K TM Q ML L TMMPAA E ya R WGLTR E EAELVKSVL A DMKPITSKSIEWFNTQ A DKQE -- W VLK N Q G EGGG HCVF 382
Cdd:PLN02977 301 S I AYH LA GT K KV Q QE L AKPGVL E -- R FLDDK E DIAKLRKCF A GLWSLDDEAAAEIVKL A IEKP el F VLK P Q R EGGG NNIY 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 383 GDD IS E Q L SQ L KP E EYD --- A WA LMQR LY P he RDVP T MA VR DTQ - QTLV T dl V SE V G LFT AY YK - G EP V T e LGGYA GYL I 457
Cdd:PLN02977 379 GDD LR E T L ER L QK E GGE dla A YI LMQR IF P -- PVSR T YL VR NGV c EEGE T -- I SE L G IYG AY LR n G DK V I - INEQS GYL L 453
490 500
....*....|....*....|....*
gi 1215145487 458 R S K P AS EN EGG IHS G KGI LDS LT L I 482
Cdd:PLN02977 454 R T K A AS SD EGG VAA G FAV LDS PY L T 478
GSH_synthase
pfam03199 Eukaryotic glutathione synthase;
202-311
6.56e-30
Eukaryotic glutathione synthase;
Pssm-ID: 460845 [Multi-domain]
Cd Length: 102
Bit Score: 112.18
E-value: 6.56e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 202 P V F L M VVQ K NE D NV Y DQ H LLE V EL QKQ - G V R TV RRT FEQ L SC Q LSS G DNQ RLL LKDVGA V D VVY L RAGY QYS DY ----- W 275
Cdd:pfam03199 1 A V V L F VVQ P NE R NV F DQ R LLE Y EL LER h G I R VI RRT LTE L LE Q TTL G PDR RLL YDGPFE V A VVY F RAGY SPD DY pseke W 80
90 100 110
....*....|....*....|....*....|....*.
gi 1215145487 276 apelnesvcchtls QT RL FM E QHHVAMNAT I SQ QLA 311
Cdd:pfam03199 81 -------------- EA RL LL E RSRAIKCPS I LT QLA 102
PTZ00055
PTZ00055 glutathione synthetase; Provisional
36-481
2.31e-26
glutathione synthetase; Provisional
Pssm-ID: 240247
Cd Length: 619
Bit Score: 112.57
E-value: 2.31e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 36 P F SIA P MTME R EVY E HLLKV T P L ITK L IS N V S E D HDF L QSSLSDMA K A D P F FGR L M E LHQQAH G EVS ------ Y R L Y par 109
Cdd:PTZ00055 79 S F VLF P LPFP R KLL E DCCLC T L L LVE L FD N M S C D LEL L LDVFEQLK K Y D K F VRD L L E ICNEVY G SGE rnikdd I R C Y --- 155
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 110 qpll LM R T D FMDDR -------------------------------- QHGA K VI E F N G I AAGMAPFGQRATEF H SFMQNQW 157
Cdd:PTZ00055 156 ---- IG R S D YFIHI dnltknktqgenefcktcyydhclcnisannq SLEF K LV E Y N T I SVAFGNLSGLLFRA H KKLLRTV 231
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 158 PNVYN D w LE DPS A TPAENQGLMQLAY ------ GI ANAARQVKSDFKEQD KP V F ------- LMV V QKNED N VY D QHLLEV E 224
Cdd:PTZ00055 232 YRECF D - LE GKG A ERPMVGSILLEKF knhfyn GI VTCFKKCHRMYLDEY KP L F gknkvcv MSI V HEDLF N FF D KYKTAN E 310
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 225 L - Q K Q G VRTVRR T FEQ L SCQLSS ------ GDNQ ---------------------- RLL L -------------- K D VGA V D 261
Cdd:PTZ00055 311 L f D K Y G IHVKTL T INE L ILLYEK kklfln YPWE tledglvrvkkyqddlhklhpg RLL I dlnsqenglnrlyk R D CFE V S 390
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 262 VVY L R agyqys DYWA P --- E LN E SVC chtls QT R L F M E QHHVAMNATISQ QL AT SK TM QM L L T ------------- MMPA 325
Cdd:PTZ00055 391 VVY F R ------ SLYS P dhm E SD E RIW ----- LV R E F L E FSDAVKIPSLPA QL VG SK RI QM Y L L dpsilkrlvslyn KRKK 459
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 326 AEYA rwgl TREEAE L V K SVL A - DMK P ITSKSIEWFNTQADKQE - WV LK N Q G EGG GHCVF G DD ISE Q L SQLKPEEYDA --- 400
Cdd:PTZ00055 460 SDKQ ---- INHDMK L L K KTF A l QVD P SLESNEHIVQDAIQNPS n YL LK P Q R EGG KNNLH G NE ISE K L RLGYKNNKEK lsq 535
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1215145487 401 WA LMQ RLY P HER dv P TMA VR d TQQTLVTDL ----- VS E V GL F -- TAYYKG E PVTE lg GYA GYL I R S K PAS E NE GG IH SG K 473
Cdd:PTZ00055 536 YV LMQ KIF P PSQ -- P AVF VR - NLKSGSFEF spens LT E L GL Y hn FIFDGN E CILN -- EQK GYL A R T K NEF E TG GG AI SG I 610
....*...
gi 1215145487 474 GILD SL T L 481
Cdd:PTZ00055 611 SSVN SL L L 618
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
