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Conserved domains on  [gi|1221423650|ref|WP_089601528|]
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MULTISPECIES: TonB-dependent vitamin B12 receptor BtuB [Enterobacter]

Protein Classification

TonB-dependent vitamin B12 receptor BtuB( domain architecture ID 11484836)

TonB-dependent vitamin B12 receptor BtuB is involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
1-615 0e+00

TonB-dependent vitamin B12 receptor BtuB;


:

Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 1207.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   1 MIKKVSLLTALSVTAFSGWAQD-SADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGM 79
Cdd:PRK10641    1 MIKKASLLTALSVTAFSGWAQDtSPDTLVVTANRFQQPVSTVLAPTTVVTRDDIDRWQSKSVNDVLRRLPGVDIAQNGGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  80 GQLSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTL 159
Cdd:PRK10641   81 GQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 160 NAGVGSHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGFDVVADGNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFVRG 239
Cdd:PRK10641  161 SAGWGSNGYQNYDGSTQQQLGDNTRVTLAGDYTYTKGFDVVAYGNTGTQAQPDRDGFMSKTLWGGLEHQFNDQWSGFVRG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 240 YGYSNRTAYDGYYSAFTPdvLVDTRQLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPHLGRYDSTATLDEIKQYNV 319
Cdd:PRK10641  241 YGYDNRTDYDAYYSPGSP--LIDTRQLYSQSWDAGLRYNGGIYSSQLIASYSHSKDYNYDPHYGRYDSSATLDDMKQYNV 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 320 QWTNSVDVGHGNIGAGVDWQKQSTEPNTNYVTNGYDLRNTGVYLTGLQKLGDFTLEGAARSDDNSQFGRHGTWQSSAAWE 399
Cdd:PRK10641  319 QWGNTVQVGHGNISAGVDWQKQTTTPGTGYVPDGYDQRNTGIYLTGQQQIGDVTLEGAARSDDNSQFGWHGTWQTSAGWE 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 400 FIEGYRFIASYGTAYKAPNLGQLYGYYGNDHLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLIDFNNNLQEYYNVGK 479
Cdd:PRK10641  399 FIDGYRFIASYGTAFKAPNLGQLYGFYGNPNLKPEESKQWEGGFEGLTGPVNWRLSGYRNDIDNLIDYDDHTLKYYNVGK 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 480 ARIKGVEATASFDTGPVMHTVGYDYVDARNATTNELLDRRAKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTNFGTYPYQK 559
Cdd:PRK10641  479 ATIKGVEWTGNFDTGPLTHQVTLDYVDPRNAITDEPLARRAKQQVKYQLDWQLYDFDWGVTYQYLGTRYDKDYSTYPYQT 558
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1221423650 560 VKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 615
Cdd:PRK10641  559 VKLGGVSLWDLAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 614
 
Name Accession Description Interval E-value
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
1-615 0e+00

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 1207.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   1 MIKKVSLLTALSVTAFSGWAQD-SADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGM 79
Cdd:PRK10641    1 MIKKASLLTALSVTAFSGWAQDtSPDTLVVTANRFQQPVSTVLAPTTVVTRDDIDRWQSKSVNDVLRRLPGVDIAQNGGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  80 GQLSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTL 159
Cdd:PRK10641   81 GQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 160 NAGVGSHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGFDVVADGNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFVRG 239
Cdd:PRK10641  161 SAGWGSNGYQNYDGSTQQQLGDNTRVTLAGDYTYTKGFDVVAYGNTGTQAQPDRDGFMSKTLWGGLEHQFNDQWSGFVRG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 240 YGYSNRTAYDGYYSAFTPdvLVDTRQLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPHLGRYDSTATLDEIKQYNV 319
Cdd:PRK10641  241 YGYDNRTDYDAYYSPGSP--LIDTRQLYSQSWDAGLRYNGGIYSSQLIASYSHSKDYNYDPHYGRYDSSATLDDMKQYNV 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 320 QWTNSVDVGHGNIGAGVDWQKQSTEPNTNYVTNGYDLRNTGVYLTGLQKLGDFTLEGAARSDDNSQFGRHGTWQSSAAWE 399
Cdd:PRK10641  319 QWGNTVQVGHGNISAGVDWQKQTTTPGTGYVPDGYDQRNTGIYLTGQQQIGDVTLEGAARSDDNSQFGWHGTWQTSAGWE 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 400 FIEGYRFIASYGTAYKAPNLGQLYGYYGNDHLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLIDFNNNLQEYYNVGK 479
Cdd:PRK10641  399 FIDGYRFIASYGTAFKAPNLGQLYGFYGNPNLKPEESKQWEGGFEGLTGPVNWRLSGYRNDIDNLIDYDDHTLKYYNVGK 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 480 ARIKGVEATASFDTGPVMHTVGYDYVDARNATTNELLDRRAKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTNFGTYPYQK 559
Cdd:PRK10641  479 ATIKGVEWTGNFDTGPLTHQVTLDYVDPRNAITDEPLARRAKQQVKYQLDWQLYDFDWGVTYQYLGTRYDKDYSTYPYQT 558
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1221423650 560 VKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 615
Cdd:PRK10641  559 VKLGGVSLWDLAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 614
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
2-615 0e+00

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 768.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   2 IKKVSLLTALS--VTAFSGWAQDSA---DSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQN 76
Cdd:TIGR01779   1 MQKSALAPALAslLTLCSALHANEAqplDTVVVTANRFAQTASQTLAPVTIITRQDIERTQAKSLPELLRRLPGVSIAQN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  77 GGMGQLSSLFIRGTNSSHVLILVDGIRLNQAGvTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD- 155
Cdd:TIGR01779  81 GGRGQNTSLFLRGTESDHVLVLIDGIRFGSAA-AGAADFQQLPVELVERIEYVRGPRSSLYGSEAIGGVINIITRRRSGg 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 156 -GTTLNAGVGSHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGFDVVADGnnGGLAQTDRDGYMNKTLYGALEHTFSEQWS 234
Cdd:TIGR01779 160 qGTTLSAGLGSLDYQEYSIASGVAIGENGWYSVALGTESTKGINVRPGG--PGVYDPDRDGFRSDSLLLGGGHRFDESWS 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 235 GFVRGYGYSNRTAYDGYySAFTPDVlvDTRQLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPHLGRYDSTAtlDEI 314
Cdd:TIGR01779 238 LFVNALRYENRNDYDNY-SFGTRLY--KEAEKGDQSFTGGRQRQSERDVSELTLSTGKSKDWDYAYSKGRYSSTS--DTR 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 315 KQYNVQWTNSVDVGHGNIGA-GVDWQKQSTEPNTNYvtNGYDLRNTGVYLTGLQKLGDFTLEGAARSDDNSQFGRHGTWQ 393
Cdd:TIGR01779 313 EQRNIQWQNDLLVGDGWVLAgGVDWQKDSIISSTAD--KEDDRSNTAAFAQVLQQWGQQLLEASLRRDDNQQFGSHTTGS 390
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 394 SSAAWEFIEGYRFIASYGTAYKAPNLGQLYG-YYGNDHLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLIDFNNNLQ 472
Cdd:TIGR01779 391 IAWGYQFIEELRFTASYGTAFKAPNLNQLYYpSYGNPNLQPETSKSAELGFYGLFSGGKWSISGYRTKINDLIDYDSHPK 470
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 473 EYYNV-GKARIKGVEATASFDTGPVMHTVGYDYVDARNATTNELLDRRAKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTN 551
Cdd:TIGR01779 471 GYPNNiGEARIKGVEATAEFATGGWTHQLSVDLLDAQNVNTGNTLPRRARQMYKWNADRAFEQFDWGASYQYVGKRYDDD 550
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1221423650 552 FGTYPYQKVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 615
Cdd:TIGR01779 551 YNTYPTQNVRLGGYSLLDLRVSYYVTDSWTVQGRIANLFDKDYETAYGYPQAGRAYYLSIRYQF 614
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
5-583 1.46e-84

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 276.74  E-value: 1.46e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   5 VSLLTALSVTAFSG-WAQDSADSL---VVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMG 80
Cdd:COG4771     4 ASLLLLLALAAQAAdALAEDATELeevVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  81 QLSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD--GTT 158
Cdd:COG4771    84 GSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDelEGS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 159 LNAGVGSHGYQNYGGS-TQQTLGDSTRVTLAGDYTYTKGFDvvadgNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFV 237
Cdd:COG4771   164 VSLGYGSNGNGTYSGSlSLGGPGDKLSFLLSGSYRDRDGYL-----DYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 238 RGYGYSNRTAYDGYY--SAFTPDVLVDTRQLYSQTWDAGLRFNEDIFHS-QLLSSYSHSKDFNYDPHLGRYDSTATLDEI 314
Cdd:COG4771   239 SGGYSRQDRDGGPPTlgDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNlDLSLYYSRTDRDSTNGSLGGSTGSFSDSDD 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 315 KQY--NVQWTNSVDVGHgNIGAGVDWQKQSTEPNTNYVTNGYDLRNTGVYLTGLQKLGD-FTLEGAARSDDNSQFGRHGT 391
Cdd:COG4771   319 TTYglELDLTYPLGGNH-TLTLGAEYRYDDLDSSSFLGGADASRDTYGLFAQDEWKLTDkLTLTAGLRYDYYSTFGASNY 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 392 WQSS----AAWEFIEGYRFIASYGTAYKAPNLGQLYGYY---------GNDHLDPEESKQWEGAFEG--LTAGVSWRVSA 456
Cdd:COG4771   398 TAFSprlgLRYDLSDNLTLRASYGRGFRAPSLAELYGSGtgtpgryvlGNPDLKPETSDNYELGLEYrlGNGGLSLSLTG 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 457 YRNDVDNLIDF------NNNLQEYYNVGKARIKGVEATASFDTGPVMH-TVGYDYVDAR--NATTNELLDRRAKQQVKYQ 527
Cdd:COG4771   478 FYTDIKDLIVLvpvgpgPGDVLQYENVGKARTYGLELELKYRLGKGLTlTASYTYLDSKidDGDTGEPLPNVPPHKANLG 557
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1221423650 528 LDTQIYD-LDWSLTYHYLGTRYDTNFGTYPYQKVkmGGVSLWDAAVSYPVTSHLTVR 583
Cdd:COG4771   558 LDYRLPKwWLLLLLTRYYGGRYVTPPSGRLEGYT--PGYTLLDLRASYKLTKNLTLS 612
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
45-615 2.55e-82

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 271.25  E-value: 2.55e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  45 TSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQlSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQ 124
Cdd:cd01347     2 VSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGG-STISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 125 RIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTLNAGVG-----SHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGfdv 199
Cdd:cd01347    81 RVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGygsdnSGSSGGGGFDVSGALADDGAFGARLYGAYRDG--- 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 200 vaDGNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFVRGYGYSNRTAYDGY---------------YSAFTPDVLVDTR 264
Cdd:cd01347   158 --DGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGtlpangtgsslgggpSSNTNGDRDWDYR 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 265 QLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDF------------NYDPHLGRYDSTATLDEIKQYNVQWTNSVDVGHGNI 332
Cdd:cd01347   236 DRYRKRASLGLEHDLNDTGWTLRANLSYSYTDndgdplilnggnNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPV 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 333 G----AGVDWQKQStepntnyvtngYDLRNTGVYLTGLQKLGD-FTLEGAARSDDNSQ--------------FGRHGTWQ 393
Cdd:cd01347   316 AhtltLGVEYRREE-----------LDEKQTALYAQDTIELTDdLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPS 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 394 SSAAWEFIEGYRFIASYGTAYKAPNLGQLYG--------YYGNDHLDPEESKQWEGAFEG-LTAGVSWRVSAYRNDVDNL 464
Cdd:cd01347   385 LGLVYKLTDGLSLYASYSQGFRAPSLGELYGggshggtaAVGNPNLKPEKSKQYELGLKYdPGDGLTLSAALFRIDIKNE 464
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 465 IDF------NNNLQEYYNVGKARIKGVEATASFD-TGPVMHTVGYDYVDARN-----ATTNELLDRRAKQQVKYQLDTQI 532
Cdd:cd01347   465 IVStptntgLGLVTVYVNGGKARIRGVELEASYDlTDGLGLTGSYTYTDTEVkrtdgATTGNRLPGIPKHTANLGLDYEL 544
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 533 YDLDWSL--TYHYLGTRYDTNFGTypYQKVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETV--------YGYQT 602
Cdd:cd01347   545 PDEGLTAggGVRYRGKQYADTANG--NNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSlsvrgsglYGYYG 622
                         650
                  ....*....|...
gi 1221423650 603 AGREYTLSGSYTF 615
Cdd:cd01347   623 PGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
235-614 1.89e-34

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 136.82  E-value: 1.89e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 235 GFVRGYGYSNRTAYDGYYSAFTPDVLVDTRQLYSQTWDAGLRFNEDIFHS-QLLSSYSHSKDFNYDPHLG---------- 303
Cdd:pfam00593  31 GLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTlRLGLRYSSLDGDYTSNSSGlsgagdylsd 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 304 -RYDSTATLDEIKQYNVQWTNSVDVGHGNIGAGVDWQKQSTEPNTNY--------VTNGYDLRNTGVYLTGLQKLGD-FT 373
Cdd:pfam00593 111 dRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYdpanpsssSYSDTTTDSYGLYLQDNIKLTDrLT 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 374 LEGAARSDDNSQFGRHG--------------TWQSSAAWEFIEGYRFIASYGTAYKAPNLGQLYGY----------YGND 429
Cdd:pfam00593 191 LTLGLRYDHYSTDGDDGngggdnfsrsysafSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSgsgggggavaGGNP 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 430 HLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLI-------DFNNNLQEYYNVGKARIKGVEATASFDT-GPVMHTVG 501
Cdd:pfam00593 271 DLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLItsdpdgpGLGGTVYTYTNVGKARIRGVELELSGRLwGLGLSGGG 350
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 502 YDYVDARNA----TTNELLDRRAKQQ----VKYQLDTQIYDLDWSLTYHYLGTRYDTNFGTYPYQkvkmGGVSLWDAAVS 573
Cdd:pfam00593 351 YTYTDADDDadadDTGNPLPNVPRHTanlgLTYDFPLGGWGARLGARYVGSGERRYGDAANTFKT----PGYTLVDLSAG 426
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1221423650 574 YPVTSHLTVRGKIANLFDKDYETVY--------GYQTAGREYTLSGSYT 614
Cdd:pfam00593 427 YRLNKNLTLRLGVNNLFDKYYKRYYssgggnlgGYPGPGRTFYLGLSYK 475
 
Name Accession Description Interval E-value
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
1-615 0e+00

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 1207.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   1 MIKKVSLLTALSVTAFSGWAQD-SADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGM 79
Cdd:PRK10641    1 MIKKASLLTALSVTAFSGWAQDtSPDTLVVTANRFQQPVSTVLAPTTVVTRDDIDRWQSKSVNDVLRRLPGVDIAQNGGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  80 GQLSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTL 159
Cdd:PRK10641   81 GQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 160 NAGVGSHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGFDVVADGNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFVRG 239
Cdd:PRK10641  161 SAGWGSNGYQNYDGSTQQQLGDNTRVTLAGDYTYTKGFDVVAYGNTGTQAQPDRDGFMSKTLWGGLEHQFNDQWSGFVRG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 240 YGYSNRTAYDGYYSAFTPdvLVDTRQLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPHLGRYDSTATLDEIKQYNV 319
Cdd:PRK10641  241 YGYDNRTDYDAYYSPGSP--LIDTRQLYSQSWDAGLRYNGGIYSSQLIASYSHSKDYNYDPHYGRYDSSATLDDMKQYNV 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 320 QWTNSVDVGHGNIGAGVDWQKQSTEPNTNYVTNGYDLRNTGVYLTGLQKLGDFTLEGAARSDDNSQFGRHGTWQSSAAWE 399
Cdd:PRK10641  319 QWGNTVQVGHGNISAGVDWQKQTTTPGTGYVPDGYDQRNTGIYLTGQQQIGDVTLEGAARSDDNSQFGWHGTWQTSAGWE 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 400 FIEGYRFIASYGTAYKAPNLGQLYGYYGNDHLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLIDFNNNLQEYYNVGK 479
Cdd:PRK10641  399 FIDGYRFIASYGTAFKAPNLGQLYGFYGNPNLKPEESKQWEGGFEGLTGPVNWRLSGYRNDIDNLIDYDDHTLKYYNVGK 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 480 ARIKGVEATASFDTGPVMHTVGYDYVDARNATTNELLDRRAKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTNFGTYPYQK 559
Cdd:PRK10641  479 ATIKGVEWTGNFDTGPLTHQVTLDYVDPRNAITDEPLARRAKQQVKYQLDWQLYDFDWGVTYQYLGTRYDKDYSTYPYQT 558
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1221423650 560 VKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 615
Cdd:PRK10641  559 VKLGGVSLWDLAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 614
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
2-615 0e+00

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 768.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   2 IKKVSLLTALS--VTAFSGWAQDSA---DSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQN 76
Cdd:TIGR01779   1 MQKSALAPALAslLTLCSALHANEAqplDTVVVTANRFAQTASQTLAPVTIITRQDIERTQAKSLPELLRRLPGVSIAQN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  77 GGMGQLSSLFIRGTNSSHVLILVDGIRLNQAGvTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD- 155
Cdd:TIGR01779  81 GGRGQNTSLFLRGTESDHVLVLIDGIRFGSAA-AGAADFQQLPVELVERIEYVRGPRSSLYGSEAIGGVINIITRRRSGg 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 156 -GTTLNAGVGSHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGFDVVADGnnGGLAQTDRDGYMNKTLYGALEHTFSEQWS 234
Cdd:TIGR01779 160 qGTTLSAGLGSLDYQEYSIASGVAIGENGWYSVALGTESTKGINVRPGG--PGVYDPDRDGFRSDSLLLGGGHRFDESWS 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 235 GFVRGYGYSNRTAYDGYySAFTPDVlvDTRQLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPHLGRYDSTAtlDEI 314
Cdd:TIGR01779 238 LFVNALRYENRNDYDNY-SFGTRLY--KEAEKGDQSFTGGRQRQSERDVSELTLSTGKSKDWDYAYSKGRYSSTS--DTR 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 315 KQYNVQWTNSVDVGHGNIGA-GVDWQKQSTEPNTNYvtNGYDLRNTGVYLTGLQKLGDFTLEGAARSDDNSQFGRHGTWQ 393
Cdd:TIGR01779 313 EQRNIQWQNDLLVGDGWVLAgGVDWQKDSIISSTAD--KEDDRSNTAAFAQVLQQWGQQLLEASLRRDDNQQFGSHTTGS 390
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 394 SSAAWEFIEGYRFIASYGTAYKAPNLGQLYG-YYGNDHLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLIDFNNNLQ 472
Cdd:TIGR01779 391 IAWGYQFIEELRFTASYGTAFKAPNLNQLYYpSYGNPNLQPETSKSAELGFYGLFSGGKWSISGYRTKINDLIDYDSHPK 470
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 473 EYYNV-GKARIKGVEATASFDTGPVMHTVGYDYVDARNATTNELLDRRAKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTN 551
Cdd:TIGR01779 471 GYPNNiGEARIKGVEATAEFATGGWTHQLSVDLLDAQNVNTGNTLPRRARQMYKWNADRAFEQFDWGASYQYVGKRYDDD 550
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1221423650 552 FGTYPYQKVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 615
Cdd:TIGR01779 551 YNTYPTQNVRLGGYSLLDLRVSYYVTDSWTVQGRIANLFDKDYETAYGYPQAGRAYYLSIRYQF 614
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
5-583 1.46e-84

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 276.74  E-value: 1.46e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   5 VSLLTALSVTAFSG-WAQDSADSL---VVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMG 80
Cdd:COG4771     4 ASLLLLLALAAQAAdALAEDATELeevVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  81 QLSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD--GTT 158
Cdd:COG4771    84 GSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDelEGS 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 159 LNAGVGSHGYQNYGGS-TQQTLGDSTRVTLAGDYTYTKGFDvvadgNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFV 237
Cdd:COG4771   164 VSLGYGSNGNGTYSGSlSLGGPGDKLSFLLSGSYRDRDGYL-----DYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 238 RGYGYSNRTAYDGYY--SAFTPDVLVDTRQLYSQTWDAGLRFNEDIFHS-QLLSSYSHSKDFNYDPHLGRYDSTATLDEI 314
Cdd:COG4771   239 SGGYSRQDRDGGPPTlgDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNlDLSLYYSRTDRDSTNGSLGGSTGSFSDSDD 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 315 KQY--NVQWTNSVDVGHgNIGAGVDWQKQSTEPNTNYVTNGYDLRNTGVYLTGLQKLGD-FTLEGAARSDDNSQFGRHGT 391
Cdd:COG4771   319 TTYglELDLTYPLGGNH-TLTLGAEYRYDDLDSSSFLGGADASRDTYGLFAQDEWKLTDkLTLTAGLRYDYYSTFGASNY 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 392 WQSS----AAWEFIEGYRFIASYGTAYKAPNLGQLYGYY---------GNDHLDPEESKQWEGAFEG--LTAGVSWRVSA 456
Cdd:COG4771   398 TAFSprlgLRYDLSDNLTLRASYGRGFRAPSLAELYGSGtgtpgryvlGNPDLKPETSDNYELGLEYrlGNGGLSLSLTG 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 457 YRNDVDNLIDF------NNNLQEYYNVGKARIKGVEATASFDTGPVMH-TVGYDYVDAR--NATTNELLDRRAKQQVKYQ 527
Cdd:COG4771   478 FYTDIKDLIVLvpvgpgPGDVLQYENVGKARTYGLELELKYRLGKGLTlTASYTYLDSKidDGDTGEPLPNVPPHKANLG 557
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1221423650 528 LDTQIYD-LDWSLTYHYLGTRYDTNFGTYPYQKVkmGGVSLWDAAVSYPVTSHLTVR 583
Cdd:COG4771   558 LDYRLPKwWLLLLLTRYYGGRYVTPPSGRLEGYT--PGYTLLDLRASYKLTKNLTLS 612
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
45-615 2.55e-82

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 271.25  E-value: 2.55e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  45 TSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQlSSLFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQFPIALVQ 124
Cdd:cd01347     2 VSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGG-STISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 125 RIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTLNAGVG-----SHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKGfdv 199
Cdd:cd01347    81 RVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGygsdnSGSSGGGGFDVSGALADDGAFGARLYGAYRDG--- 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 200 vaDGNNGGLAQTDRDGYMNKTLYGALEHTFSEQWSGFVRGYGYSNRTAYDGY---------------YSAFTPDVLVDTR 264
Cdd:cd01347   158 --DGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGtlpangtgsslgggpSSNTNGDRDWDYR 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 265 QLYSQTWDAGLRFNEDIFHSQLLSSYSHSKDF------------NYDPHLGRYDSTATLDEIKQYNVQWTNSVDVGHGNI 332
Cdd:cd01347   236 DRYRKRASLGLEHDLNDTGWTLRANLSYSYTDndgdplilnggnNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPV 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 333 G----AGVDWQKQStepntnyvtngYDLRNTGVYLTGLQKLGD-FTLEGAARSDDNSQ--------------FGRHGTWQ 393
Cdd:cd01347   316 AhtltLGVEYRREE-----------LDEKQTALYAQDTIELTDdLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPS 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 394 SSAAWEFIEGYRFIASYGTAYKAPNLGQLYG--------YYGNDHLDPEESKQWEGAFEG-LTAGVSWRVSAYRNDVDNL 464
Cdd:cd01347   385 LGLVYKLTDGLSLYASYSQGFRAPSLGELYGggshggtaAVGNPNLKPEKSKQYELGLKYdPGDGLTLSAALFRIDIKNE 464
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 465 IDF------NNNLQEYYNVGKARIKGVEATASFD-TGPVMHTVGYDYVDARN-----ATTNELLDRRAKQQVKYQLDTQI 532
Cdd:cd01347   465 IVStptntgLGLVTVYVNGGKARIRGVELEASYDlTDGLGLTGSYTYTDTEVkrtdgATTGNRLPGIPKHTANLGLDYEL 544
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 533 YDLDWSL--TYHYLGTRYDTNFGTypYQKVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETV--------YGYQT 602
Cdd:cd01347   545 PDEGLTAggGVRYRGKQYADTANG--NNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSlsvrgsglYGYYG 622
                         650
                  ....*....|...
gi 1221423650 603 AGREYTLSGSYTF 615
Cdd:cd01347   623 PGRTYYLSVSYKF 635
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
28-321 7.08e-62

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 206.26  E-value: 7.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  28 VVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQLSSLFIRGTNSSHVLILVDGIRLNQA 107
Cdd:COG4206     2 VVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGGPGSAASISIRGLGSNQTLVLIDGVPLNDP 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 108 GvTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDG--TTLNAGVGSHGYQNYGGSTQQTLGDsTRV 185
Cdd:COG4206    82 S-LGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGfkGSVSASYGSFGTRRLSASLSGGAGK-FSY 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 186 TLAGDYTYTKGFDVVADGNNgglaqtDRDGYMNKTLYGALEHTFSEQWSGFVRGYGYSNRTAYDGYYSAFtpdvlvdtrq 265
Cdd:COG4206   160 SLSASYRRSDGYRYNDPDLR------NNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSERGYPGAVGSD---------- 223
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1221423650 266 lYSQTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPhlGRYDSTATLDEIKQYNVQW 321
Cdd:COG4206   224 -RNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDG--GGDSAGTSNTDGARAGLSY 276
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
25-605 3.12e-59

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 209.30  E-value: 3.12e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  25 DSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGqlSSLFIRGTNSSH--VLILVDGI 102
Cdd:COG1629     2 EEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGA--GQISIRGFGGGGnrVLVLVDGV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 103 RLNQAGvTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGT--TLNAGVGSHGYQNYGGSTQQTlG 180
Cdd:COG1629    80 PLNDPS-GGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKggEVSASYGSYGTYRASLSLSGG-N 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 181 DSTRVTLAGDYTYTKGFdvvadgnngglaqTDRDGYMNKTLYGALEHTFSEQWS---------------GFVRGYGYSNR 245
Cdd:COG1629   158 GKLAYRLSASYRDSDGY-------------RDNSDSDRYNLRAKLGYQLGDDTRltlsasysdsdqdspGYLTLAALRPR 224
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 246 TAYDGYYSAFTPDVLVDTRQLYS-----QTWDAGLRFNEDIFHSQLLSSYSHSKDFNYDPhLGRYDSTATLDEIKQYNVQ 320
Cdd:COG1629   225 GAMDDGTNPYSNDTDDNTRDRYSlsleyEHLGDGLKLSASAYYRYDDTDLDSDFTPTPAD-GGTLEQTDFDNRTYGLELR 303
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 321 WTNSVDVGHG-NIGAGVDWQKQSTE--------------PNTNYVTNGYDLRNTGVYLTGLQKLGD-FTLEGAARSDDNS 384
Cdd:COG1629   304 LTYDLGFGGKhTLLVGLDYQRQDLDgsgypldlgsgslpTLTSGADDDGTTTSLALYAQDTYKLTDkLTLTAGLRYDYVS 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 385 QFGRHGTWQS----------------SAAWEFIEGYRFIASYGTAYKAPNLGQLYGY------YGNDHLDPEESKQWE-G 441
Cdd:COG1629   384 YDVDDTVTGTdsasgsrsysafspslGLTYQLSPNLSLYASYSRGFRAPTFGELYANgtdpysVGNPDLKPETSTNYElG 463
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 442 A-FEGLTAGVSWRVSAYRNDVDNLIDF-----NNNLQEYY-NVGKARIKGVEATASFDTGPVMHT-VGYDYVDARN---- 509
Cdd:COG1629   464 LrYRLLDGRLSLSLALFYSDVDNEILSvplpnDSGFSTYYtNAGKARSYGVELELSYQLTPGLSLnASYSYTDAKFdddt 543
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 510 ----ATTNELLDRRAKQQVKYQLDTQIYD-LDWSLTYHYLGTRYDTNFGTYPYqkvkMGGVSLWDAAVSYPVTSHLTVRG 584
Cdd:COG1629   544 dgsaDLDGNRLPGVPPLTANLGLTYEFPGgWSLGLGVRYVGDRYLDDANTQGA----PGGYTLVDLGAGYRFGDNLTLSL 619
                         650       660
                  ....*....|....*....|.
gi 1221423650 585 KIANLFDKDYETVYGYQTAGR 605
Cdd:COG1629   620 GVDNLFDKKYATSLSVRASNV 640
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
8-615 6.73e-50

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 184.33  E-value: 6.73e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   8 LTALSVTAFSGWAQDSADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQlSSLFI 87
Cdd:COG4773    32 LPEVTVTGTAEGTGGYTAKSSSTATKLDTPLRETPQSVSVVTRQLIEDQGATTLDDALRNVPGVTVSSYDGGGR-DSFSI 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  88 RGTNSSHvlILVDGIRLNQAGVTgssdlsQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD--GTTLNAGVGS 165
Cdd:COG4773   111 RGFSIDN--YLRDGLPLGGFGGG------QPDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAepQGEVSLSAGS 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 166 HG-------------------------------YQNYGGSTQQT--------LGDSTRVTLAGDYTYTKG-FDVVADGNN 205
Cdd:COG4773   183 WDtyratadvggplnedgtlryrlnaayedgdsFRDGVDNRRTLiapsldwdLTDDTTLTLGAEYQDDDStGDRGFLPLD 262
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 206 GGLAQTDRDGYMN----------KTLYGALEHTFSEQWSgfVRGYGYSNRTAYDGYYSAFTPDVLVDTRQLYSQTWDAGL 275
Cdd:COG4773   263 GTLLDLPRSTNLGepwdyydtetTTLFAELEHRFNDDWS--LRANARYSDSDRDGRSAYAYGAPDAATGTLTRYASARDG 340
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 276 RFNEDIFhsQLlssyshskDFNYDPHLGRYDSTATL--DEIKQYNVQWTNSVDVghGNIGAGVDWqkQSTEPNTNYVTNG 353
Cdd:COG4773   341 DSRSDSL--DA--------NLNGKFETGGLEHTLLVgaDYSRYDSDSDSATAGT--INIYNPVYG--NLPEPDFDASDTD 406
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 354 YDLRNTGVYLTGLQKLGD-FTLEGAARSDDNSQFGRHG-------------TWQSSAAWEFIEGYRFIASYGTAYKaPNL 419
Cdd:COG4773   407 TTTRQTGLYAQDQISLTDrLSLLLGGRYDWYETDSTNRlggsttsyddsafTPRAGLVYDLTPGLSLYASYSESFE-PQS 485
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 420 GQlyGYYGNDhLDPEESKQWE-GA-FEGLTAGVSWRVSAYRNDVDN-LIDFNNNLQEYYNVGKARIKGVEATASfdtGPV 496
Cdd:COG4773   486 GA--DNNGNP-LDPETGKQYEaGVkGELFDGRLNATLAVFDITQKNvATTDPDNPNFYVQVGEVRSRGVELELS---GEL 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 497 MH----TVGYDYVDARNATTNELLD---------RRAKQQVKYQLDTQIYDlDWSLT--YHYLGTRYDTNFGTypyqkVK 561
Cdd:COG4773   560 TPglnlIAGYTYTDAKITKDADALEgkrltnvprHTASLWTTYRFPSGALK-GLGLGggVRYVGERYGDAANT-----FT 633
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1221423650 562 MGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQT-----AGREYTLSGSYTF 615
Cdd:COG4773   634 LPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYYASSGSRGyvyygAPRNVRLSLSYKF 692
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
6-615 1.42e-49

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 182.78  E-value: 1.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   6 SLLTALSVTAfsgwAQDSADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGmgQLSSL 85
Cdd:PRK10064   16 AISCAWPVLA----VDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGD--NRKGV 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  86 FIRGTNSSHVLILVDGIRLNQAGVT---GSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD------- 155
Cdd:PRK10064   90 SIRGLDSSYTLILIDGKRVNSRNAVfrhNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQkwhgtvt 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 156 -----------GTTLNAGV--------GSHGYQNYGGSTQQTLGD--STRVTLAGDYTYTKGFdvvadgnngglaqTDRD 214
Cdd:PRK10064  170 vdttiqehrdrGDTYNGQFftsgplidGVLGMKAYGSLAKREKDDpqNSTTTDTGETPRIEGF-------------TSRD 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 215 GYMNKTLYGALEHTFSEqwsgfvrGYGYSNRTaydgyYSAFTPDVLVDTRQLYSQT----WDAG---LRF------NEDI 281
Cdd:PRK10064  237 GNVEFAWTPNQNHDFTA-------GYGFDRQD-----RDSDSLDKNRLERQNYSLShngrWDYGnseLKYygekveNKNP 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 282 FHSQLLSSYSHSKDfnydphlGRYdsTATLDEIKQYnvqwtnsvdvghgnIGAGVDWQKQSTEPNTNYVTNGYDLRNTGV 361
Cdd:PRK10064  305 GNSSPITSESNSID-------GKY--TLPLTAINQF--------------LTFGGEWRHDKLSDAVNLTGGTSSKTSASQ 361
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 362 YLTGLQK----LGDFTLEGAARSDDNSQFGRHGTWQSSAAWEFIEGYRFIASYGTAYKAPNLGQLYGYY----------- 426
Cdd:PRK10064  362 YALFVEDewriFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWtsnscrgacki 441
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 427 -GNDHLDPEESKQWE-GAF----EGLTAGVSWRVSAYRNDVDNLID------------------FNNNLQ-------EYY 475
Cdd:PRK10064  442 vGSPDLKPETSESWElGLYymgeEGWLEGVESSVTVFRNDVDDRISisrtsdvnaapgyqnfvgFETNGRgrrvpvfRYY 521
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 476 NVGKARIKGVEATASFDTGPVMH-TVGYDYVDARNATT--NELLDRRAKQQVKYQLDTQIYDL-DWS--LTYHYLG-TRY 548
Cdd:PRK10064  522 NVNKARIQGVETELKIPFNDEWKlSLNYTYNDGRDVSNgeNKPLSDLPFHTANGTLDWKPLALeDWSfyVSGNYTGqKRA 601
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1221423650 549 DTNFGTYPyqkvkmGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYE-TVYGYQTAGREYTLSGSYTF 615
Cdd:PRK10064  602 DSATAKTP------GGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSrDDYSYNEDGRRYFMAVDYRF 663
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
24-615 3.13e-49

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 181.82  E-value: 3.13e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  24 ADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDtAQNGGMGQLSSLFIRGTNSSHVLILVDGIR 103
Cdd:TIGR01785   1 LDTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVPGVD-VTGGGRPPGQSINIRGLQDNRVLVVVDGAR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 104 LNQAGVTGSSDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTtlnagvgsHGYQNYGGSTQQTLG--- 180
Cdd:TIGR01785  80 QNYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLL--------RPGQLFGGLAKLSYGsnn 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 181 DSTRVTLAGDYTYTKGFDVVA-----DGNN-GGLAQTD--RDGYMNKTLYGALE-HTFSEQWSGFvrGYGYsNRTAYDGY 251
Cdd:TIGR01785 152 NSFGGSVAVAGRLDDNLDALVaatyrDGGNyRNGNKEEatNSAYVQKNLLAKLGwQLDDAQRLEF--SYFT-TEGSLDEA 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 252 YSAFTPDvlvDTRQLYSQTWDA--------GLRFNEDIFHSQLLS---SYSHSKDFNYDPHLGRYDSTATLDEIKQYNVQ 320
Cdd:TIGR01785 229 QNSGPGT---EYVLGSSSTLLAsstrdrsaTLTYNWTPEDNPWLDataSLYYNRTENDNDRSARGVGREEGYQYTTYGAT 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 321 WTNSVDVGHGN---IGAGVDWQKQSTEP---------NTNYVTNGYDLRNTGVYLTGLQKLGD--FTLEGAARSD----- 381
Cdd:TIGR01785 306 LQNTSRFDVASwstLTYGVDWMKDKRRTesfdpnsvtTIVPNPPSAKEYFFGLFLQDNIPLLDdrLTLSAGLRYDhykls 385
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 382 -------DNSQFGrHGTWQSSAA--WEFIEGYRFIASYGTAYKAPNLGQLYG------------YYGNDHLDPEESKQWE 440
Cdd:TIGR01785 386 pkttadtEAVDRS-YSRWSPSLGlsYKPVDWLTLYASYSQGFRAPSIDELYGtgdhpgtpggytFAPNPNLKPETSKTWE 464
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 441 -GA---FEGLTAG---VSWRVSAYRNDVDNLIDF-----------NNNLQEYYNVGKARIKGVEATASFDTGPVMHTVGY 502
Cdd:TIGR01785 465 lGAnlsFDNLLLDndqLQFKVAYFYNDVKDFIDLtigvtdnvtagMNNITQYVNIDGARIRGIEASASYDAGLWATGLSY 544
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 503 DYVDARNATTNELLDRRAKQQVKYQLDTQIYDLDWSLT---YHYlgTRYDTNFGTY---PYQKVKMGGVSLWDAAVSYPV 576
Cdd:TIGR01785 545 GYTIGKDQNTNQWLSNIPPLKLVVTVGYRFPDRRLDLGakaAYY--ERQSESPTTEdvaANGLLTTPGYTVVDLYATYQP 622
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|...
gi 1221423650 577 T--SHLTVRGKIANLFDKDYETVYGYQTA--GREYTLSGSYTF 615
Cdd:TIGR01785 623 NavKGLTVRFGVNNLTDRKYTPAQSVPGAgpGRNFKGSVKYQF 665
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
33-615 4.28e-48

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 178.15  E-value: 4.28e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  33 RFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVdTAQNGGMGQLSSLFIRGTNSShVLILVDGIRLNqagvtgs 112
Cdd:COG4774     1 KTDTPLLDTPQSVTVVTRELIEDQGATSLADALRNVPGV-TFGAGEGGNGDSFSIRGFSAS-GDIYVDGLRDP------- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 113 sDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDG--TTLNAGVGSHGYQ------------------NYG 172
Cdd:COG4774    72 -GQYRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEpfTEVTLTYGSDGQRratldvngplgddlayrlNGM 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 173 GSTQQT-------------------LGDSTRVTLAGDYTYTkgfDVVADG-----NNGGLAQTDRDGYMN---------- 218
Cdd:COG4774   151 YRDSDSyrdgvdndrwgiapsltwrLGDRTRLTLDYEYQDD---DRTPDYgvpavANGRPVDVDRSTFYGqpddysdset 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 219 KTLYGALEHTFSEQWSgFVRGYGYSNrtaYDGYYSAFTPDVLVDTRQLYSQTWDAglRFNEDIFHSQLlssyshskDFNY 298
Cdd:COG4774   228 DSATLRLEHDFNDNWT-LRNALRYSD---YDRDYRNTYPTGGNATGTVTRSAYRR--DQDNDTLSNQT--------DLTG 293
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 299 DPHLGRYDST----ATLDEIKQYNVQWTNSVDVGHGNIGAGVDWQkQSTEPNTNYVTNGYDLRNTGVYLTGLQKLGD--- 371
Cdd:COG4774   294 KFDTGGVKHTllagVEYSREDSDNARYSGGGTAPTVNLYNPVYGA-PVTGPTLGGADNDSRTDTTGLYLQDTISLTDrws 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 372 ---------FTLEGAARSDDNSQFGRHG---TWQSSAAWEFIEGYRFIASYGTAYkAPNLGQLYGYYGNDHLDPEESKQW 439
Cdd:COG4774   373 llaglrydrFDTDYTDRTTGATTSSYDDsafSPRAGLVYKPTPNLSLYASYSTSF-NPGGGAPSLSNAGQALDPEKSRQY 451
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 440 E-GA-FEGLTAGVSWRVSAYRNDVDNLIDFN-NNLQEYYNVGKARIKGVEATASFDTGPVMH-TVGYDYVDAR--NATTN 513
Cdd:COG4774   452 EvGVkWDLLDGRLSLTAALFRIEKTNVRTTDpANPGVYVQTGEQRSRGVELEATGELTPGWSvLAGYTYLDAEitKSANA 531
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 514 ELLDRR----AKQQ----VKYQLDTQiyDLDWSLTYHYLGTRYDTNFGTypyqkVKMGGVSLWDAAVSYPVTSHLTVRGK 585
Cdd:COG4774   532 ANVGNRlpnvPRHSaslwTTYDLPLP--GLTLGGGVRYVGSRYADAANT-----VKLPSYTRFDAGASYRLNKNLTLRLN 604
                         650       660       670
                  ....*....|....*....|....*....|....*
gi 1221423650 586 IANLFDKDY-ETVYGYQT----AGREYTLSGSYTF 615
Cdd:COG4774   605 VNNLTDKRYyASAYGSGYvtpgAPRTVLLSASYRF 639
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
2-615 1.05e-44

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 169.34  E-value: 1.05e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   2 IKKVSLLTALSVTAFSGWAQDSADSLVVTANRF-EQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMG 80
Cdd:COG4772     1 MRRALAAALLLAAAAAAEAATTLETVVVTGSRAaEARLKDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDGFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  81 QLSSLFIRGTN---SSHVLILVDGIRLNQAGVT-GSSDLSQfPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRA--K 154
Cdd:COG4772    81 LRPNIGIRGLGprrSRGITLLEDGIPIAPAPYGdPAAYYFP-DLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIptA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 155 DGTTLNAGVGSHGYQNYGGSTQQTLGDstrVTLAGDYTYTKGfdvvaDG---NNGglaqTDRDGYMNKTLYgalehTFSE 231
Cdd:COG4772   160 FGGELRVTGGSFGYRRTHASVGGTVGN---FGYLVEYSRKRG-----DGfrdNSG----FDINDFNAKLGY-----RLSD 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 232 --QWSGFVRGYGYSNRT--------AYDGYYSAFTPDVLVDTRQL-----YSQTWDAGLRFNedifhsqlLSSYSHSKDF 296
Cdd:COG4772   223 rqELTLKFQYYDEDANTpggltdaqFDADPRQSYRPADQFDTRRTqlslrYEHQLSDNTTLT--------TTAYYNDFSR 294
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 297 NYDPHLGRYDSTATLDEIK----QYNVQ-----WTNSVDVG--HGNIGAGVDWQKQST-----EPNTNYVTNGYDLR--- 357
Cdd:COG4772   295 NWYIRQNTADPNTPGLGLRgnprGYRSYgieprLTHRFELGgvPHTLEVGLRYHREEEdrkqyVNTYGQGRSGAGLRrdr 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 358 -----NTGVYLTG-LQKLGDFTLEGAARSD------DNSQFGRHGTWQS------------SAAWEFIEGYRFIASYGTA 413
Cdd:COG4772   375 rfsadALAAYAQNrFELTGRLTLTPGLRYEhirrdrTDRYSTRTGGDDSgsnsyseflpglGLLYQLTDNLQLYANVSRG 454
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 414 YKAPNLGQL-YGYYGNDHLDPEESKQWEGAFEG-LTAGVSWRVSAYRNDVDNLIDFNNN----LQEYYNVGKARIKGVEA 487
Cdd:COG4772   455 FEPPTFGDLaYGNGGNPDLKPEKSWNYELGTRGrIGNGLSAEVALFYIDYDNELGSCSAaggdRSTFTNAGETRHQGLEL 534
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 488 TASFDTGPVMH-----TVGYDYVDAR--NATTNELLDRR----AKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTNFGT-Y 555
Cdd:COG4772   535 ALDYDLLKGGGlglplFAAYTYTDAEftSDFGPVFAGNRlpyvPRHQLTAGLGYEHGGWTANLNGRYVSEQFTDAANTvA 614
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1221423650 556 PYQKVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYET------VYGYQTA-GREYTLSGSYTF 615
Cdd:COG4772   615 DGSFGKIPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYIAsrapnyAAGIRPGpPRTVYAGLRLKF 681
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
25-615 2.76e-44

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 168.36  E-value: 2.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  25 DSLVVTANRFEQPE----KSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQnGGMGQLSSLFIRGTNSSHVLILVD 100
Cdd:TIGR01786   1 DTITVTATRTADPQrrdlSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVE-GGRGGSQGINIRGLDKNRVAVLVD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 101 GIRLNQ----AGVTGSSDLSqFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTLNAGVGSHGYQNYGGSTQ 176
Cdd:TIGR01786  80 GIRQNTsyggQGSTFYAINS-IDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSSANN 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 177 QTLGDST------RVTLAGDYTYTKGFDVVADGNNGGLAQTDRD-----GYMNKTLYGALEHTFSEQWS-GFVRGYGYSN 244
Cdd:TIGR01786 159 RFTQSVAaagrndDVDALVQATYRRGHELKNGNKANIGNESKRSkpnpsDYKSQSFLAKLGWQLNDAHRlGLSLEYTQTD 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 245 RTAYDGYYSAFTPDVLVDTRQLY------SQTWDA--GLRF-----NEDIFHSQLLSSYSHSKDFNYDPHLGRYDSTaTL 311
Cdd:TIGR01786 239 YDEPEMTNTSYLTKPLGAPLLSStvvlgdSKTRDRrtGLDYelnpdNSWLDTVKLALDKQYIQLYNYLNATSASDYP-GV 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 312 DEIKQYNvQWTNSV------------DVGHGNIGAGVDWQKQSTEPN---TNYVTNGYDL------------RNTGVYLT 364
Cdd:TIGR01786 318 DKNGRYK-DKYDYYtlgfdtnnkiefSVHSLSLTYGLDRFKDKVSTGdsrRNLPTAAYNLygyegenrpvkgSNFGLFLQ 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 365 GLQKLGD-FTLEGAARSDDNSQFG---------------RHGTWQSSAAWEFIEGYRFIASYGTAYKAPNLGQLYGYY-- 426
Cdd:TIGR01786 397 DNIKLGDwLSLSAGLRYDHYKTDPkadeskdygaisktySRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGah 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 427 ---------GNDHLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLID--------------FNNNLQEYYNVGKARIK 483
Cdd:TIGR01786 477 pgggpytflPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDlgigvtakgnmaqvGSNTITNYVNIDNARIR 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 484 GVEATASFDTGPVMH-------TVGYDYVDARNATTNELLD----RRAKQQVKYQLDTQIYDLDWSLTyHYLGTRYDTNF 552
Cdd:TIGR01786 557 GIELSGRYDLGSFFSgpdgwttTLKYGYTKGKDSDTNPWLNaitpLKVVLGLGYDHPDEKWGVGLTLT-FSGAKDAVDAY 635
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 553 GTYPYQKVKMGGVS-------LWDAAVSYPVTSHLTVRGKIANLFDKDY----------ETVYGYQTAGREYTLSGSYTF 615
Cdd:TIGR01786 636 ATYYENGEAAKAGPlrtpsytVVDLYGYYKPNKNLTLRFGVYNLLDRKYttwesarqagPLATGYTAPGRNYKASVEYKF 715
PRK13483 PRK13483
ligand-gated channel protein;
5-615 5.22e-42

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 161.10  E-value: 5.22e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   5 VSLLTALS-VTAFSGWAQDSADS----LVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVdTAQNGGM 79
Cdd:PRK13483    9 ISALCLLPaVFVTHALAQAAPDKtmetVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGV-VVTGGGD 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  80 GQLSSLfiRGTNSSHVLILVDGIRLNQAGVTGSSDLSQF------PIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRA 153
Cdd:PRK13483   88 RTDISL--RGMGSQYTLILVDGKRQSSRETRPNSDGPGVeqawtpPLAAIERIEVIRGPMSSLYGSDAIGGVINIITRKV 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 154 KD--------GTTL----------------NAGVGSH--GYQNYGGSTQQTLGD---------STRVTLAGDYTYTKGFD 198
Cdd:PRK13483  166 PNewqgevrlDTTLqensdsgnvyqanffvNGPLIKDllGLQLYGQYTQREEDDieggyrdkdARSLTAKLALTPNEDHD 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 199 VVADgnnGGLAQTDRDGYMNKTLYGALEHTFSEQwsgfvRGYGYSNRTAYDGYYSAFTpdvlvdtrqlYSQTWDAGlrfn 278
Cdd:PRK13483  246 IMLE---VGTSNQERDSTVGKTVAPLAPGESCGR-----RGCPESSTTEYERSTVSLS----------HTGRWDFG---- 303
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 279 edifhsqllSSYSHSKdfnYDphlgRYDSTATLDEIKQYNVQ--WTNSVDVGHgNIGAGVDWQKQSTEPNT-NYVTNGYD 355
Cdd:PRK13483  304 ---------TSDTYIQ---HE----EFDNKSREMKIKNTDFQssLVAPLGQEH-TLTFGAAYNHQDLTDETsNQISDLTD 366
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 356 LRNT--GVYLTGLQKLG-DFTLEGAARSDDNSQFGRH------GTWQSSAAWEFIEGyrfiasYGTAYKAPNL------- 419
Cdd:PRK13483  367 ISRTqwAVFSEDEWRIAdDFALTGGLRLDHDENFGGHvsprvyGVWNLAPSWTVKGG------VSTGFRAPSLrqttpdw 440
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 420 GQLYG---YYGNDHLDPEESKQWE-GAFEGLTAGVSWRVSAYRNDVDNLI---------------DFNNNLQEYYNVGKA 480
Cdd:PRK13483  441 GQVSRggnIYGNPDLKPETSLNKElGLYYDLGSGLTASLTVFYNEFKDKItrvacpatqctdgpnQFGADPTTYVNIDEA 520
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 481 RIKGVEATASFD-TGPVMHTVGYDYVDARNaTTNELLDRRAKQQVKYQLDTqiyDLDWSLT--------YHYLGTRYDTN 551
Cdd:PRK13483  521 VTQGVEASLSYPiTSTLSLSGNYTYTDSEQ-KSGAYKGSPLNQLPKHLFQA---SLNWEPTdrlnswarVNYRGEESQPT 596
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1221423650 552 FGtyPYQ-KVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDY-ETVYGYQTAGREYTLSGSYTF 615
Cdd:PRK13483  597 TG--PSSsSFIAPSYTFLDLGANYQLTDNLKLSAGIYNLFDKEInYEEYGYVEDGRRYWLGMTYSF 660
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
44-615 6.77e-42

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 160.66  E-value: 6.77e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  44 ATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQLSSLFIRGTNSShvlILVDGIRLNQAGVTGSSDLSQFPIALV 123
Cdd:TIGR01783   5 SVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRGFGLE---VDIDNVYLDGVPLLSRGNLAIVDPAMV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 124 QRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD--GTTLNAGVGSHGYQNYGGSTQQTLGDSTRVTLAGDYTYTKG---FD 198
Cdd:TIGR01783  82 ERVEVLRGPASLLYGGSAPGGVINIVTKRPQDepKGSVTFGAGTRSGYRTAFDLGGPLGADGTFRGRLNGARQDGdsfYD 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 199 VVADGNNGGLAQTD--RDGYMNKTL---YGALEHTFSEQWSGFVRGyGYSNRTAYDGYYSAfTPDVLVDTRQLYSQTWDA 273
Cdd:TIGR01783 162 GAGEETRLGATATDwqLDDRTLLRLgayYQKERDRGGYGGLPASGG-TSGRDLSSDRYLGT-SSNRNYDDREYLSYGLSL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 274 GLRFNEDIFHSQLLSsYSHSKDFNYDPHLGRYDSTATLDEIKQYNV---QWTNSVDVGHG----------NIGAGVDWQK 340
Cdd:TIGR01783 240 EYQFNDVWTGKQNLR-YSYFDTDSNQVQASGYSSDGGLFGRSLTVVnvkQDRVQIDAGLDgefetgpiehDLLLGVSYGQ 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 341 QSTEPNTNYVTNGYDLRN---------------------------TGVYLTGLQKLGDFTLEGAARSDDNSQFGRHG--- 390
Cdd:TIGR01783 319 RTTNRFNNTGYPSDNIYSltatssartdigdspkdralssttkalNGVALQRILLADKWTLTLGGRYDSVDVKSNNGvag 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 391 ----------TWQSSAAWEFIEGYRFIASYGTAYKAPNLGQLYGYYGNDHLDPEESKQWEGAFEG-----LTAGVSWrvs 455
Cdd:TIGR01783 399 stgkrddsqfTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNSGDILEPEKGKNYELGVRYdlgdsLLATAAL--- 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 456 aYRNDVDNLID-FNNNLQEYYNVGKARIKGVEATASFDTGP-VMHTVGYDYVDAR------NATTNELLDRRAKQQVKYQ 527
Cdd:TIGR01783 476 -FRITKDNQLVqDPVNGTFSVNAGKTRNRGVELEARGYLTPgLSLSAGYTYTDAEftedtnGDTQGNTVPFVPKHTASLW 554
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 528 LDTQIYDLDWSLTYhYLGTRYDTNFGTYPYQKVKMGGVSLWDAAVSYPVTS--HLTVRGKIANLFDKDYETVYGYQT--- 602
Cdd:TIGR01783 555 ASYAPPVGDNGLTL-GGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKkkNLTLALNVNNLFDRDYYTSGYRWGpsa 633
                         650
                  ....*....|....*...
gi 1221423650 603 -----AGREYTLSGSYTF 615
Cdd:TIGR01783 634 yiypgAPRTVGLSVSYDF 651
PRK13486 PRK13486
TonB-dependent receptor;
7-613 1.06e-41

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 160.57  E-value: 1.06e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   7 LLTALSVTAFSgwAQDSADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVD----TAQNGGMgql 82
Cdd:PRK13486   10 VIPCLGFSASS--IAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDvesgTGKTGGL--- 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  83 sSLFIRGTNSSHVLILVDGIRLNqagvtGSSDLS-----------QFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITT 151
Cdd:PRK13486   85 -EISIRGMPASYTLILIDGVRQG-----GSSDVTpngfsamntgfMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 152 RAKD--GTTLNAGVGSHGYQNYG-----------------------GSTQQTLGDS---------TRV---TLAGDYTYT 194
Cdd:PRK13486  159 KNADkwLSSVNAGLNLQESNKWGnssqfnfwssgplvddsvslqvrGSTQQRQGSSvtslsdtaaTRIpypTESQNYNLG 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 195 KGFDVVADGNNGGLAQTD--------RDGYMNkTLYGALEHTFSeqwsgfvrgygYSNRTAYDGYYSAFTpdvlvdtrql 266
Cdd:PRK13486  239 ARLDWKASEQDVLWFDMDttrqrydnRDGQLG-SLTGGYDRTLR-----------YERNKISAGYDHTFT---------- 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 267 ySQTWDAGLRFNEDIFHSQLLSSYSHSKDfnydphlgRYDSTATLDEIKQYNVQWTNSVDVGHGN---IGAGVDWQKQST 343
Cdd:PRK13486  297 -FGTWKSYLNWNETENKGRELVRSVLKRD--------KWGLAGQPRELKESNLILNSLLLTPLGEshlVTVGGEFQSSSM 367
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 344 EPNTNYVTNGYDLRNT--GVYLTGLQKLGD-FTLEGAARSDDNSQFGRHGTWQSSAAWEFIEGYRFIASYGTAYKAPNLG 420
Cdd:PRK13486  368 KDGVVLASTGETFRQKswSVFAEDEWHLTDaLALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMG 447
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 421 QLY------------GYYGNDHLDPEESKQWEGAF-----EGLTAGVSWRVSAYRNDVDNLiDFNNNLQEYYNVGKARIK 483
Cdd:PRK13486  448 QLHkgisgvsgqgktNLLGNPDLKPEESVSYEAGVyydnpAGLNANVTGFMTDFSNKIVSY-SINDNTNSYVNSGKARLH 526
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 484 GVEATASFD--TGPVMHTVGYDYVDARNATTNEL---LDRRAKQQVKYQLDTQIY-DLDWSLTYHYLGT--RYDTNFGTY 555
Cdd:PRK13486  527 GVEFAGTLPlwSEDVTLSLNYTWTRSEQRDGDNKgapLSYTPEHMVNAKLNWQITeEVASWLGARYRGKtpRFTQNYSSL 606
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1221423650 556 P--YQKV---KMGGVSLW---DAAVSYPVTSHLTVRGKIANLFDKDYETVYGYQtAGREYTLSGSY 613
Cdd:PRK13486  607 SavQKKVydeKGEYLKAWtvvDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYS-AGKSTLYAGDY 671
PRK13513 PRK13513
ligand-gated channel protein;
8-615 2.15e-39

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 153.39  E-value: 2.15e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   8 LTALSVTAFSGWAQDSA---DSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAqngGMGQLSS 84
Cdd:PRK13513   16 AAAISSQAYAAEKTNTAtptDTMVVTASGFQQRIQDAPASISVVTREQLENKAYRDVTDALKDVPGVVVT---GGGSTSD 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  85 LFIRGTNSSHVLILVDGIRLNQAGVTGSSDLSQF------PIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGtt 158
Cdd:PRK13513   93 ISIRGMAAKYTLILVDGKRVDTRSTRPNSDGSGIeqgwlpPLAAIERIEVVRGPMSSLYGSDAMGGVINIITRKVQKE-- 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 159 lnagvgshgyqnYGGStqqtlgdstrvtLAGDYTYTKgfdvvaDGNNGGLAQTDR-------DGYMNKTLYGALEHTFSE 231
Cdd:PRK13513  171 ------------WHGS------------LRADATLQE------DSKSGDIFQTNAyasgpliDGLLGLKVSGLLSHRSED 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 232 QwsgFVRGYGySNRTAYDGYYSAFTPDvlvDTRQLysqTWDAGlRFNED-------IFHSQLLSSYSHSKDFNYD-PHLG 303
Cdd:PRK13513  221 K---IIDGYN-EQRMRNGTATFSLTPD---DNNEF---DFEIG-RYVQDrnstpgrTLALNGTNSDTQYDRNNYAiTHNG 289
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 304 RYD-----STATLDEI-------KQYNVQWTN--SVDVGHGNIGAGVDWQKQSTEPNTNYVTNGYDLRNTGVYLTGL--- 366
Cdd:PRK13513  290 YYDfgnstSYIQRDETrnpsrqmKSVDTIFNTqtSFLLDDHTLSLGGQYRYEELYDKGNQLPSASDLNKLTRWSWALfae 369
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 367 ---QKLGDFTLEGAARSDDNSQFGRHGTWQSSAAWEFIEGYRFIASYGTAYKAPNL-------GQLYG-------YYGND 429
Cdd:PRK13513  370 dewQMTNDFALTGGIRMDQDQNYGTHWTPRLYGVWHLADQWTLKGGVSTGYRSPDLrqatdnwGQLTGggglpalILGNS 449
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 430 HLDPEESKQWEGAF-----EGLTAGVSW-------RVSAYRN----DVDNLIDFNNN----LQEYYNVGKARIKGVEATA 489
Cdd:PRK13513  450 DLKPEKSISQEIGIlwdnqENLNASVTLfntdfkdKITEVRNcdttNTDGQCVFNGInydfISDRINVDKANMRGVEATF 529
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 490 SFDTGPVMHTVG-YDYVDARNATTN---ELLDRRAKQQVKYQLDTQIY-DLD-WSL------TYHYLgTRYDTNFGTYPY 557
Cdd:PRK13513  530 NWDINQAWSLATnYTFTQSEQKSGAfagQPLNQMPKHMANATLNWQTTeDFAtWIRinyrgkTSEYL-NRTSMGSGTPSY 608
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 558 QKVkmggvslwDAAVSYPVTSHLTVRGKIANLFDK--DYETvYGYQTAGREYTLSGSYTF 615
Cdd:PRK13513  609 TFV--------DLGASYQLTKELRLMGGVYNLLDKrvDIDV-NDKVLDGRRYMVGASYDF 659
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-615 4.63e-36

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 144.40  E-value: 4.63e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   1 MIKKVSLLTALSVT-----AFSGWAQDSA---------DSLVVTAnrfEQPEKSVLAaTSVVTREDID-RWQSTTVIDVM 65
Cdd:PRK13524    1 MNKKIHSLALLVNLgiygvAQAAEAEDAKtddtpasheDTIVVTA---AEQNLQAPG-VSTITAEDIRkRPPANDVSEII 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  66 RRLPGVDTAQNGGMGQLSS---LFIRGTNSSHVLILVDG--------IRLNQAGVTGS-SDLSQFPIALVQRIEYIRGPR 133
Cdd:PRK13524   77 RTMPGVNLTGNSTSGQRGNnrqIDIRGMGPENTLILIDGkpvssrnsVRYGWRGERDTrGDTNWVPPEMIERIEVLRGPA 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 134 SAVYGSDAIGGVVNIITTRAKDGTTlnagvGS-HGYQN-----YGGSTQQT-------LGDSTRVTLAGDYTYT------ 194
Cdd:PRK13524  157 AARYGNGAAGGVVNIITKKPTGEWH-----GSwNTYFNapehkAEGATKRTnfslsgpLGDELSFRLYGNLNKTqadawd 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 195 --KGFDVVADGNNGGLAQTDRDGYMNKTLYGALEHTFSEQWS-GFvrGYGYSNR-TAYDGYYSAFTPDVLVD------TR 264
Cdd:PRK13524  232 inQGHQSARTGSYAGTLPAGREGVINKDINGLLRWDFAPLQSlEL--EAGYSRQgNLYAGDTQNTNSDALVKslygkeTN 309
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 265 QLYSQT--------WDAGLRFNedifhSQLLSSYSHSKDFN----------YDPHLGRYdSTATLDEIK---QYNVQWTN 323
Cdd:PRK13524  310 RMYRQNyalthrggWDNGVSTS-----NYAQYEHTRNSRLPeglaggtegiFNEKATQF-STIDLDDVMlhsEVNLPFDL 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 324 SVDvghGNIGAGVDWQKQS-TEP--NTNYVTNGYDL--------------RNTGVYLTGLQKLGDFT-LEGAARSDDNSQ 385
Cdd:PRK13524  384 LVN---QTLTLGTEWNQQRmKDPssNTQALTSGGAIpgvsatgrspyskaEIFSLFAEDNMELTDSTmLTPGLRFDHHSI 460
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 386 FGRHgtWQSS--AAWEFIEGYRFIASYGTAYKAPNLGQL---YGYY-----------------GNDHLDPEESKQWEGAF 443
Cdd:PRK13524  461 VGNN--WSPSlnLSQGLGDDFTLKMGIARAYKAPNLYQTnpnYILYskgqgcyasagngcylqGNDDLKAETSVNKEIGL 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 444 E----GLTAGVSWrvsaYRNDVDNLI-----------DFNNNLQEYYNVGKARIKGVEATASFDTGP-VMHTVGYDY-VD 506
Cdd:PRK13524  539 EfkrdGWLAGLTW----FRNDYRNKIeagyvpvgtnsVGKTDIYQWENVPKAVVEGLEGTLNVPVSEtVNWTNNLTYmLQ 614
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 507 ARNATT------------NELLDRRAKQQVKYQLDTQIYDLDWSLTYHYLGTRYDTNfgtypyQKVKMGGVSLWDAAVSY 574
Cdd:PRK13524  615 SKNKTTgdplsiipeytlNSTLSWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGS------ATKEVSPYSIVGLSATY 688
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|.
gi 1221423650 575 PVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF 615
Cdd:PRK13524  689 DVTKNVSLTGGVDNLFDKRLWREGNAQTTGDLIAGAGAYTY 729
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
5-615 5.82e-36

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 143.74  E-value: 5.82e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   5 VSLLTALSVTAFSGWAQDSADSLVVTANRfEQPEKSVLAaTSVVTREDIDRWQSTT-VIDVMRRLPGVDTAQNGGMGQLS 83
Cdd:PRK13528   15 LLVGLNSPVSAAESSDDDNGETMVVEATA-EQELKQQPG-VSIITAEDIKKRPPVNdLSDIIRKMPGVNLTGNSASGTRG 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  84 S---LFIRGTNSSHVLILVDG--------IRLNQAGVTGS-SDLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITT 151
Cdd:PRK13528   93 NnrqIDIRGMGPENTLILIDGvpvtsrnsVRYSWRGERDTrGDTNWVPPEMVERIEVIRGPAAARYGSGAAGGVVNIITK 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 152 RAKDGTTlnagvGSHGY------QNYGGSTQQT--------LGDSTRVTLAGDYTYTKGFDVVADGNNGGLAQTDRDGYM 217
Cdd:PRK13528  173 RPTNDWH-----GSLSLytnqpeSSKEGATRRAnfslsgplAGDALTMRLYGNLNKTDADSWDINSSAGTKNAAGREGVR 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 218 NKTLYGALEHTFSEQwSGFVRGYGYS---NRTAYDGYYSAFT--PDVLVD----TRQLYSQTWDAGLRFNEDIFHSQLLS 288
Cdd:PRK13528  248 NKDINGVLSWKMTPQ-QILDFEAGYSrqgNIYAGDTQNSNSSavTESLAKsgkeTNRLYRQNYGLTHNGIWDWGQSRLGF 326
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 289 SYSHSKDFNYDPHL-----GRYDSTATLDEIKQYNVQWTNSVDVG-----HGNIGAGVDWQKQSTE-PN-TNYVTNGYDL 356
Cdd:PRK13528  327 YYEKTNNTRMNEGLagggeGRITADQTFTTSRLESYRTSGELNVPlnwlfEQTLTVGAEWNRDELNdPSsTSLTVKDGDI 406
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 357 ----------------RNTGVYLT-GLQKLGDFTLEGAARSDDNSQFGrhGTWQSS--AAWEFIEGYRFIASYGTAYKAP 417
Cdd:PRK13528  407 ggisgsaadrssknksEISALYVEdNIEPVPGTNLIPGLRFDYHSEFG--SNWSPSlnLSQELGDYFKVKAGIARAFKAP 484
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 418 NLGQ------LY-------------GYY--GNDHLDPEESKQWEGAFE----GLTAGVSWRVSAYRN------DVDNLID 466
Cdd:PRK13528  485 NLYQssegylLYsrgngcpkditsgGCYlvGNKNLDPEISVNKEIGLEftvdDYHASVTYFRNDYQNkivagdDVIGRTA 564
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 467 FNNNLQEYYNVGKARIKGVEATASFdtgPVMHtvgyDYVDAR-NA---------------------TTNELLDRRAKQQV 524
Cdd:PRK13528  565 SGAYILQWQNGGKAVVEGLEGNLLV---PLMK----DRLNWNtNAtymitseqkdtgnplsvipkyTINSTLDWQITQAL 637
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 525 KYQLDTQIYDLDWSLTYHYLGTRYDTNFGTYpyqkvKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKD-YETVYG---Y 600
Cdd:PRK13528  638 SANVNWTLYGKQKPRTHAESRSEETGGLSGK-----ELGAYSLVGVNVNYDINKNLRLNVGVSNLFDKQiYREGEGantY 712
                         730
                  ....*....|....*
gi 1221423650 601 QTAGREYTLSGSYTF 615
Cdd:PRK13528  713 NEPGRAYYAGVTASF 727
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
235-614 1.89e-34

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 136.82  E-value: 1.89e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 235 GFVRGYGYSNRTAYDGYYSAFTPDVLVDTRQLYSQTWDAGLRFNEDIFHS-QLLSSYSHSKDFNYDPHLG---------- 303
Cdd:pfam00593  31 GLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTlRLGLRYSSLDGDYTSNSSGlsgagdylsd 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 304 -RYDSTATLDEIKQYNVQWTNSVDVGHGNIGAGVDWQKQSTEPNTNY--------VTNGYDLRNTGVYLTGLQKLGD-FT 373
Cdd:pfam00593 111 dRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYdpanpsssSYSDTTTDSYGLYLQDNIKLTDrLT 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 374 LEGAARSDDNSQFGRHG--------------TWQSSAAWEFIEGYRFIASYGTAYKAPNLGQLYGY----------YGND 429
Cdd:pfam00593 191 LTLGLRYDHYSTDGDDGngggdnfsrsysafSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSgsgggggavaGGNP 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 430 HLDPEESKQWEGAFEGLTAGVSWRVSAYRNDVDNLI-------DFNNNLQEYYNVGKARIKGVEATASFDT-GPVMHTVG 501
Cdd:pfam00593 271 DLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLItsdpdgpGLGGTVYTYTNVGKARIRGVELELSGRLwGLGLSGGG 350
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 502 YDYVDARNA----TTNELLDRRAKQQ----VKYQLDTQIYDLDWSLTYHYLGTRYDTNFGTYPYQkvkmGGVSLWDAAVS 573
Cdd:pfam00593 351 YTYTDADDDadadDTGNPLPNVPRHTanlgLTYDFPLGGWGARLGARYVGSGERRYGDAANTFKT----PGYTLVDLSAG 426
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1221423650 574 YPVTSHLTVRGKIANLFDKDYETVY--------GYQTAGREYTLSGSYT 614
Cdd:pfam00593 427 YRLNKNLTLRLGVNNLFDKYYKRYYssgggnlgGYPGPGRTFYLGLSYK 475
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
37-145 3.41e-30

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 114.29  E-value: 3.41e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  37 PEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVdTAQNGGMGQLSSLFIRGTNSSHVLILVDGIRLNQAGvTGSSDLS 116
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGV-SVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGG-GGSVDLN 78
                          90       100
                  ....*....|....*....|....*....
gi 1221423650 117 QFPIALVQRIEYIRGPRSAVYGSDAIGGV 145
Cdd:pfam07715  79 SIDPEDIERVEVLKGPASALYGSGAIGGV 107
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
5-548 3.44e-29

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 122.81  E-value: 3.44e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   5 VSLLTALSVTAFSGWAQDSADSLVVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQLSs 84
Cdd:PRK13484   11 IAVMCSAVISSGYASSDKKEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITGGNEKPDIS- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  85 lfIRGTNSSHVLILVDGIRLN--QAGVTGSSDLSQF---PIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGTTl 159
Cdd:PRK13484   90 --IRGLSGDYTLILVDGRRQSgrESRPNGSGGFEAGfipPVEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNNQTW- 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 160 nagvgsHGYQNYGGSTQQT--LGDSTR--VTLAGDYTYTK-GFDVVADGNnggLAQTDRDGYM-----NKTLYGALEHTF 229
Cdd:PRK13484  167 ------DGVLGLGGIIQEHgkFGNSTTndFYLSGPLIKDKlGLQLYGGMN---YRKEDSISQGtpakdNKNITATLQFTP 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 230 SEQWSgFVRGYGYSN--RTAYDG-YYSAFT-------PDVLVDTRQLYSQtWDAGLRFNEDIFHSQL------------- 286
Cdd:PRK13484  238 TESQK-FVFEYGKNNqvHTLTPGeSLDAWTmrgnlkqPNSKRETHNSRSH-WVAAWNAQGEILHPEIavyqekvirevks 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 287 --LSSYSHSkDFNYDPHlgRYDSTATLDEIKQYNVQWTNSVDVG----HGNIGAGVDWQKQSTEpntnyvTNGYDLRNTG 360
Cdd:PRK13484  316 gkKDKYNHW-DLNYESR--KPEITNTIIDAKVTAFLPENVLTIGgqfqHAELRDDSATGKKTTE------TQSVSIKQKA 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 361 VYLTGLQKLGD-FTLEGAARSDDNSQFGRHGTWQSSAAWEFIEGYRFIASYGTAYKAPNLGQL---YG---------YYG 427
Cdd:PRK13484  387 VFIENEYAATDsLALTGGLRLDNHEIYGSYWNPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVspgFGtltqggasiMYG 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 428 NDHLDPEESKQWEGAF-----EGLTAGVSWRVSAYRNDVDNL----ID--FNNNLQEYYNVGKARIKGVEATASFDTGPV 496
Cdd:PRK13484  467 NRDLKPETSVTEEIGIiysndSGFSASATLFNTDFKNKLTSYdigtKDpvTGLNTFIYDNVGEANIRGVELATQIPVYDK 546
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1221423650 497 MH-TVGYDYVDARNATTNEL----------LDRRAKQQVKYQLDTQiYDLDWSLtyhYLGTRY 548
Cdd:PRK13484  547 WHvSANYTFTDSRRKSDDESlngkslkgepLERTPRHAANAKLEWD-YTQDITF---YSSLNY 605
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
36-158 5.26e-10

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 62.61  E-value: 5.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  36 QPEKSVLAATSVVTREDIDRWQSTTVIDVMR-RLPGVDTAQNGGM-GQLSSLFIRGTNS----SHVLILVDGirlnqagV 109
Cdd:TIGR04056  89 QKKKSLTGAVSTVKAKELKKVPVSNLSNALQgKVAGVIITQSSGEpGGDAEIWIRGISSfggnNSPLYVIDG-------V 161
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1221423650 110 TGSSDLSQFPIALVQRIEYIRGPRS-AVYGSDAIGGVVnIITT-RAKDGTT 158
Cdd:TIGR04056 162 PRDNGLSDLNPEDIESISVLKDASAtAIYGSRGANGVI-LITTkRGKEGKP 211
PRK14050 PRK14050
TonB-dependent siderophore receptor;
30-194 7.65e-10

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 61.74  E-value: 7.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  30 TANRFEQPEKSVLAATSVVTREDIDRWQSTTVID-VMRRLPGVDTAQNGGMGQLSSLFIRGTNSSHVLILVDGIRLNQAG 108
Cdd:PRK14050   68 TGSKTDTPITEIPQSVSVVGRQEMDDRGVTNKVDeALRYTPGVLSQPFGTDGDTDWFYIRGFDATQTGVFLDGLNLFSYG 147
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 109 VTGSsdlsQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKDGT--TLNAGVGSHGYQNYGGSTQQTLGDST--- 183
Cdd:PRK14050  148 FGGF----QIDPFMLERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDEPlyYTEIGINSYGNAFTGFDVGDKLSDDGtvr 223
                         170
                  ....*....|....
gi 1221423650 184 -RVT--LAGDYTYT 194
Cdd:PRK14050  224 yRVTgkVAGGDNYS 237
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
23-209 1.16e-09

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 61.36  E-value: 1.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  23 SADSlvVTANRFEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDT---AQNGGMGQLSSLFIRGTNSSHVlILV 99
Cdd:PRK09840   55 APDQ--SADPKFSQPLADTTQTITVISEQVIKDQGATNLTEALRNVPGVGTffaGENGNTTTGDAIYMRGFDTSNS-IYV 131
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 100 DGIRlnqagVTGSSDLSQFPIalvQRIEYIRGPRSAVYGSDAIGGVVNIITTRA--KDGTTLNAGVGSHGYQNYGGSTQQ 177
Cdd:PRK09840  132 DGIR-----DIGSISRDTFNT---EQVEVIKGPSGTDYGRSAPTGSINMISKQPrnDSGIDASASIGSAWFRRGTLDVNQ 203
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1221423650 178 TLGDST--RVTLAGDYTYTKGFDVVADgNNGGLA 209
Cdd:PRK09840  204 VIGDTTavRLNVMGEKTHDAGRDKVKN-ERYGVA 236
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
2-594 1.45e-09

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 60.93  E-value: 1.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   2 IKKVSLLTALSVTAFSGWAQDSA----DSLVVTANRFEQ-----PEKSVLA---AT---------------SVVTREDID 54
Cdd:PRK10044   13 LRKIAVVVATAVSGMSVYAQAAVepkeETITVTAAPAPQesawgPAATIAAkrsATgtktdtpiektpqsiSVVTAEEMA 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  55 RWQSTTVIDVMRRLPGVDTAQNGGMGQLSSLFIRGTNSSHVL--ILVDGIRLnQAgvTGSSDLSQFPIALvQRIEYIRGP 132
Cdd:PRK10044   93 LHQPKSVKEALSYTPGVSVGTRGASNTYDHLIIRGFAASGQSqnNYLDGLKL-QG--NFYNDAVIDPYML-ERAELMRGP 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 133 RSAVYGSDAIGGVVNIITTRA----------KDGT-TL------------NAGVGSHGYQNYGGST--QQTLGDSTRVTL 187
Cdd:PRK10044  169 VSVLYGKSNPGGLLNMVSKRPtteplkevqfKMGTdNLfqtgfdfsdaldDDGVYSYRLTGLARSAnaQQKGSEEQRYAI 248
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 188 A----------GDYTYTKGFD---------------VVADGNNGGLAQTD-RDGYMNKTL--------YgALEHTFSEQW 233
Cdd:PRK10044  249 ApsftwrpddkTNFTFLSYFQnepetgyygwlpkegTVEPLPNGKRLPTDfNEGAKNNTYsrnekmvgY-SFDHEFNDTF 327
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 234 SgfVR-GYGYS-NRTAYDGYY-SAFTPD--------VLVDTRQLYSQTWDAGLRFN---EDIFHSQLLS-SYSHSK-DFN 297
Cdd:PRK10044  328 T--VRqNLRYAeNKTSQRSVYgYGVCSDkghylnrgYVVDDEKLQNFSVDTQLQSKfatGDVDHTLLTGvDFMRMRnDIN 405
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 298 YDphlgrYDSTATLDEIKQYNVQWTNSVDVGHGNIGAGVDWQKQS-------TEPNTNYVTNG--YDLRNTGVY--LTGl 366
Cdd:PRK10044  406 AW-----FGYADSVPLLNLYGPVNTDFDFNANSGPYQILNKQKQTglyvqdqAEWDKWLVTLGgrYDWADQSSLnrVNG- 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 367 qklgdftleGAARSDDNsQFgrhgTWQSSAAWEFIEGYRFIASYGTAYKaPNLGQlyGYYGNDhLDPEESKQWEgafegl 446
Cdd:PRK10044  480 ---------TTDKRDDK-QF----TWRGGVNYLFDNGITPYFSYSESFE-PSSGT--GKDGNI-FAPSKGKQYE------ 535
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 447 tAGVSW---------RVSAYRNDVDN--LIDFNNNLqeyYNV--GKARIKGV--EATASFdTGPVMHTVGYDYVDARNAT 511
Cdd:PRK10044  536 -AGVKYvpkdrpivvTGAVYQLTKTNnlTADPENSF---FSVqgGEIRARGVelEAKAAL-SANVNVTGSYTYTDAEYTT 610
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650 512 TNELLDRRAKQQVKYQL---------DTQIYDLDWSLTYHYLGTRYDTnfgtyPYQKVKMGGVSLWDAAVSYPVT----- 577
Cdd:PRK10044  611 DTTYKGNTPAQVPKHMAslwadytffDGPLSGLTLGTGGRYTGSSYGD-----PANSFKVGSYTVVDALVKYDLArfgma 685
                         730
                  ....*....|....*...
gi 1221423650 578 -SHLTVrgKIANLFDKDY 594
Cdd:PRK10044  686 gSSVAL--NVNNLFDREY 701
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
25-164 2.00e-09

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 60.81  E-value: 2.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650  25 DSLVVTANRfEQPEKSVLA------ATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQLSSlfIRGTNSSHVLIL 98
Cdd:TIGR01782   2 DAVQVTGQR-ASLEKAIDAkrdadsVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVS--VRGLGPSYNRTT 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1221423650  99 VDGIRLNQAGVTG-SSDLSQFPIALVQRIEYIRGPrSAVYGSDAIGGVVNIITTRAKD--GTTLNAGVG 164
Cdd:TIGR01782  79 LNGRTIASTDSGGrAFSLDLLPSELVSGVEVYKTP-TADMDEGGIGGTVDLRTRSPFDydGRTLSGSAQ 146
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
6-155 8.99e-05

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 45.66  E-value: 8.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1221423650   6 SLLTALSVTAFSGWAQDsADSLVVTANR----FEQPEKSVLAATSVVTREDIDRWQSTTVIDVMRRLPGVDTAQNGGMGQ 81
Cdd:PRK14049   41 TALETLVVNGGSGGVIT-ADGYVATSSAtgakVDTPFLETPQSISSVTEQQLKDRNPQTLLETLAYTPGARVGAFGFDPR 119
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1221423650  82 LSSLFIRGTNSSHVLILVDGIRlnQAGVTgSSDLSQFPIALvQRIEYIRGPRSAVYGSDAIGGVVNIITTRAKD 155
Cdd:PRK14049  120 FDAFFVRGFDVTYTGVFRDNLR--QPGAS-SSIFKTEPYGL-EGVSILRGPSSALYGASGAGGLFNLITKRPTE 189
PRK10003 PRK10003
ferric-rhodotorulic acid outer membrane transporter; Provisional
553-615 1.87e-03

ferric-rhodotorulic acid outer membrane transporter; Provisional


Pssm-ID: 236640 [Multi-domain]  Cd Length: 729  Bit Score: 41.39  E-value: 1.87e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1221423650 553 GTYPYQKVKMGGVSLWDAAVSYPVTSHLTVRGKIANLFDKDYET------VYGyqtAGREYTLSGSYTF 615
Cdd:PRK10003  664 TPYGTFRAEQGSYALVDLFTRYQVTKNFSVQGNVNNLFDKTYDTnvegsiVYG---APRNFSITATYQF 729
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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