|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
1-396 |
0e+00 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 575.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 1 MNQHLDPVVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLS 80
Cdd:PRK06954 2 TAVDQDPIVIASAARTPMAAFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 81 QAAQCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQVLDHMFLDGLEDAYERGR 160
Cdd:PRK06954 82 LSVGCTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPYLLPKARGGMRMGHGQVLDHMFLDGLEDAYDKGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 161 LMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQPPKARPDKIPGLKPAFR 240
Cdd:PRK06954 162 LMGTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTVAGKKGDTVIDRDEQPFKANPEKIPTLKPAFS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 241 EGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEIN 320
Cdd:PRK06954 242 KTGTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEIN 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1222381029 321 EAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIELY 396
Cdd:PRK06954 322 EAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATAMGIELI 397
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
6-394 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 537.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 6 DPVVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQC 85
Cdd:COG0183 2 REVVIVDAVRTPFGRFGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMgHGQVLDHMFLDGLEDAYErGRLMGTF 165
Cdd:COG0183 82 VTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRM-NAKLVDPMINPGLTDPYT-GLSMGET 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 166 AEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQP-PKARPDKIPGLKPAFREGGT 244
Cdd:COG0183 160 AENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVPDRKGEVVVDRDEGPrPDTTLEKLAKLKPAFKKDGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 245 VTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFA 324
Cdd:COG0183 240 VTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLIEINEAFA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 325 VVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:COG0183 320 AQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCIGGGQGIALIIE 389
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
9-394 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 520.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTTL 88
Cdd:cd00751 1 VIVSAVRTPIGRFGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 89 NKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQvLDHMFLDGLEDAYErGRLMGTFAED 168
Cdd:cd00751 81 NRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNT-LDGMLDDGLTDPFT-GLSMGITAEN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 169 CAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQP-PKARPDKIPGLKPAFREGGTVTA 247
Cdd:cd00751 159 VAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVPGRKGPVVVDRDEGPrPDTTLEKLAKLKPAFKKDGTVTA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 248 ANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFAVVP 327
Cdd:cd00751 239 GNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEAFAAQA 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 328 MVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:cd00751 319 LACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGGQGAAMVIE 385
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
8-395 |
1.16e-171 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 484.98 E-value: 1.16e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTT 87
Cdd:PLN02644 3 VCIVGVARTPIGGFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSANLGQAPARQAALGAGLPPSTICTT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQVLDHMFLDGLEDAYERGRlMGTFAE 167
Cdd:PLN02644 83 VNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKYLPEARKGSRLGHDTVVDGMLKDGLWDVYNDFG-MGVCAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 168 DCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRER--RLVATDEQPPKARPDKIPGLKPAFRE-GGT 244
Cdd:PLN02644 162 LCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPGGRGRpsVIVDKDEGLGKFDPAKLRKLRPSFKEdGGS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 245 VTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFA 324
Cdd:PLN02644 242 VTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQVDYYEINEAFS 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1222381029 325 VVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIEL 395
Cdd:PLN02644 322 VVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGICNGGGGASAIVVEL 392
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
8-394 |
1.08e-170 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 482.34 E-value: 1.08e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTT 87
Cdd:PRK05790 4 VVIVSAARTPIGKFGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEVPALT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQVLDHMFLDGLEDAYErGRLMGTFAE 167
Cdd:PRK05790 84 INKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPHVLPGSRWGQKMGDVELVDTMIHDGLTDAFN-GYHMGITAE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 168 DCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR-ERRLVATDEQP-PKARPDKIPGLKPAFREGGTV 245
Cdd:PRK05790 163 NLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIKQRKgDPVVVDTDEHPrPDTTAESLAKLRPAFDKDGTV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 246 TAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFAV 325
Cdd:PRK05790 243 TAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLDLIEINEAFAA 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1222381029 326 VPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK05790 323 QALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCIGGGQGVALIVE 391
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
10-394 |
4.32e-144 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 414.32 E-value: 4.32e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 10 IVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTTLN 89
Cdd:TIGR01930 1 IVAAARTPIGKFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 90 KMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARA-RGGYRMGHGQVLDHMFLDgLEDAYErGRLMGTFAED 168
Cdd:TIGR01930 81 RQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRSlRWGVKPGNAELEDARLKD-LTDANT-GLPMGVTAEN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 169 CAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQP-PKARPDKIPGLKPAFREGGTVTA 247
Cdd:TIGR01930 159 LAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGRKGPVTVSSDEGIrPNTTLEKLAKLKPAFDPDGTVTA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 248 ANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFAVVP 327
Cdd:TIGR01930 239 GNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAFAAQV 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 328 MVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:TIGR01930 319 LACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGGQGAAVILE 385
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
9-396 |
2.75e-141 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 407.56 E-value: 2.75e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTTL 88
Cdd:PRK08235 5 VIVSAARTPFGKFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQTETV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 89 NKMCGSGMQALMLGhDQLL-AGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQVLDHMFLDGLEDAYeRGRLMGTFAE 167
Cdd:PRK08235 85 NKVCASGLRAVTLA-DQIIrAGDASVIVAGGMESMSNAPYILPGARWGYRMGDNEVIDLMVADGLTCAF-SGVHMGVYGG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 168 DCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR-ERRLVATDEQP-PKARPDKIPGLKPAFREGGTV 245
Cdd:PRK08235 163 EVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIPQRKgDPIVVAKDEAPrKDTTIEKLAKLKPVFDKTGTI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 246 TAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFAV 325
Cdd:PRK08235 243 TAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEINEAFAA 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1222381029 326 VPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIELY 396
Cdd:PRK08235 323 VALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSGGGQGDAVLIEVH 393
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
8-394 |
1.18e-122 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 360.36 E-value: 1.18e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTT 87
Cdd:PRK05656 4 VVIVAATRTAIGSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVPAMT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQVLDHMFLDGLEDAYERGRlMGTFAE 167
Cdd:PRK05656 84 LNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVLPGARTGLRMGHAQLVDSMITDGLWDAFNDYH-MGITAE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 168 DCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLV-ATDEQP-PKARPDKIPGLKPAFREGGTV 245
Cdd:PRK05656 163 NLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIPQRKGEPLAfATDEQPrAGTTAESLAKLKPAFKKDGSV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 246 TAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFAV 325
Cdd:PRK05656 243 TAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEANEAFAA 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1222381029 326 VPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK05656 323 QSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALAIE 391
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
8-394 |
9.11e-114 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 337.70 E-value: 9.11e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQA-PARQAALGAGLSQAAQCT 86
Cdd:PRK09051 5 VVVVSGVRTAIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEPRDMyLSRVAAINAGVPQETPAF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 87 TLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQVLDHMfLDGLEDAYERGRlMGTFA 166
Cdd:PRK09051 85 NVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWGARMGDAKLVDMM-VGALHDPFGTIH-MGVTA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 167 EDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQP-PKARPDKIPGLKPAFR-EGGT 244
Cdd:PRK09051 163 ENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEIKTRKGEVVFDTDEHVrADTTLEDLAKLKPVFKkENGT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 245 VTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFA 324
Cdd:PRK09051 243 VTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVADLDVIEANEAFA 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 325 VVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK09051 323 AQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCIGGGQGIAAIFE 392
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
8-394 |
2.23e-100 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 303.80 E-value: 2.23e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLER-AGLAAEAVDTVLMGCVLQAGQ-GQAPARQAALGAGLSQAAQC 85
Cdd:PRK09050 4 AFICDAIRTPIGRYGGALSSVRADDLGAVPLKALMARnPGVDWEAVDDVIYGCANQAGEdNRNVARMSALLAGLPVSVPG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMgHGQVLDHM----FLDGLEDAYERGRL 161
Cdd:PRK09050 84 TTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPFVMGKADSAFSR-QAEIFDTTigwrFVNPLMKAQYGVDS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 162 MGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR-ERRLVATDEQP-PKARPDKIPGLKPAF 239
Cdd:PRK09050 163 MPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIPQKKgDPVVVDRDEHPrPETTLEALAKLKPVF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 240 REGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEI 319
Cdd:PRK09050 243 RPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPATRKLLARLGLTIDQFDVIEL 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 320 NEAFAVVPMVAMRELGIAHD--KLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK09050 323 NEAFAAQGLAVLRQLGLADDdaRVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYALCTMCIGVGQGIALAIE 399
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
8-395 |
4.33e-98 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 297.31 E-value: 4.33e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTT 87
Cdd:PRK06366 4 VYIVSAKRTAIGKFGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVTKYT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLArarGGYRMGHGQVL-------DHMFLDGLEDA--YER 158
Cdd:PRK06366 84 VNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLLP---SDLRWGPKHLLhknykidDAMLVDGLIDAfyFEH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 159 grlMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEAsqgrerrlVATDEQPPKARPDKIPGLKPA 238
Cdd:PRK06366 161 ---MGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFND--------LDRDEGIRKTTMEDLAKLPPA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 239 FREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFE 318
Cdd:PRK06366 230 FDKNGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKSIDYYDLVE 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 319 INEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIEL 395
Cdd:PRK06366 310 HNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLCHGGGGAHTLTLEM 386
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
8-394 |
2.19e-97 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 296.13 E-value: 2.19e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGcvlQA-GQGQAPA--RQAALGAGLSQAAQ 84
Cdd:PRK06205 4 AVICEPVRTPVGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFG---QGyPNGEAPAigRVAALDAGLPVTVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 85 CTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMGHGQvldhmfldgLEDAYERGRL--- 161
Cdd:PRK06205 81 GMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTDMRWGVRGGGVQ---------LHDRLARGREtag 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 162 ---------MGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR-ERRLVATDEQP-PKARPD 230
Cdd:PRK06205 152 grrfpvpggMIETAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVPQRKgDPTVVDRDEHPrADTTLE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 231 KIPGLKP---AFREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARI 307
Cdd:PRK06205 232 SLAKLRPimgKQDPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 308 EWTLETVDLFEINEAFAVVPMVAMRELGIA---HDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIG 384
Cdd:PRK06205 312 GLTLDDIDLIELNEAFAAQVLAVLKEWGFGaddEERLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMCIG 391
|
410
....*....|
gi 1222381029 385 GGEATAVAIE 394
Cdd:PRK06205 392 GGQGLAAVFE 401
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
7-394 |
9.69e-97 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 294.25 E-value: 9.69e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 7 PVVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCT 86
Cdd:PRK06633 4 PVYITHAKRTAFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVPGY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 87 TLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMS---NAPYLlaraRGGYRMGHGQVLDHMFLDGLEDAYErGRLMG 163
Cdd:PRK06633 84 TINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSlgmHGSYI----RAGAKFGDIKMVDLMQYDGLTDVFS-GVFMG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 164 TFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQppkARPDK----IPGLKPAF 239
Cdd:PRK06633 159 ITAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVTIKKTTSLFDHDET---VRPDTsleiLSKLRPAF 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 240 REGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEI 319
Cdd:PRK06633 236 DKNGVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEV 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1222381029 320 NEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK06633 316 NEAFAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCIGGGMGMAMCVE 390
|
|
| pcaF |
TIGR02430 |
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, ... |
8-394 |
2.10e-91 |
|
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, an enzyme that acts at the end of pathways for the degradation of protocatechuate (from benzoate and related compounds) and of phenylacetic acid.
Pssm-ID: 131483 Cd Length: 400 Bit Score: 280.52 E-value: 2.10e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLER-AGLAAEAVDTVLMGCVLQAGQ-GQAPARQAALGAGLSQAAQC 85
Cdd:TIGR02430 3 AYICDAIRTPIGRYGGSLSSVRADDLAAVPIKALLARnPQLDWAAIDDVIYGCANQAGEdNRNVARMAALLAGLPVSVPG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMG---HGQVLDHMFLDGLEDAYERGRLM 162
Cdd:TIGR02430 83 TTVNRLCGSGLDAIGMAARAIKAGEADLLIAGGVESMSRAPFVMGKADSAFSRSakiEDTTIGWRFINPLMKALYGVDSM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 163 GTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR-ERRLVATDEQP-PKARPDKIPGLKPAFR 240
Cdd:TIGR02430 163 PETAENVAEEFGISREDQDAFALRSQQRTAAAQASGFFAEEIVPVVIPQKKgEPTVVDQDEHPrPETTLEGLAKLKPVVR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 241 EGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEIN 320
Cdd:TIGR02430 243 PDGTVTAGNASGVNDGAAALLLASEEAVQRHGLTPRARILAAATAGVEPRIMGIGPVPATQKLLARAGLSIDQFDVIELN 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1222381029 321 EAFAVVPMVAMRELGIAHD--KLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:TIGR02430 323 EAFAAQALAVLRELGLADDdaRVNPNGGAIALGHPLGASGARLVLTALRQLERSGGRYALCTMCIGVGQGIALAIE 398
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
8-264 |
3.03e-91 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 275.34 E-value: 3.03e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTT 87
Cdd:pfam00108 1 VVIVSAARTPFGSFGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLAR-ARGGYRMGHGQVLDHMFLDGLEDAYErGRLMGTFA 166
Cdd:pfam00108 81 INKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTdARSGLKHGDEKKHDLLIPDGLTDAFN-GYHMGLTA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 167 EDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQP-PKARPDKIPGLKPAFREGGTV 245
Cdd:pfam00108 160 ENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGKPTVDKDEGIrPPTTAEPLAKLKPAFDKEGTV 239
|
250
....*....|....*....
gi 1222381029 246 TAANASSISDGAAALLLMR 264
Cdd:pfam00108 240 TAGNASPINDGAAAVLLMS 258
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
10-394 |
7.16e-89 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 273.51 E-value: 7.16e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 10 IVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGqGQAP--ARQAALGAGLSQAAQCTT 87
Cdd:PRK07801 6 IVDAVRTPVGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIG-PQAGniARTSWLAAGLPEEVPGVT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARG-----GYRMGHGQVLDHMFLDGlEDAYERGrlm 162
Cdd:PRK07801 85 VDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAMTAGeqlgfTSPFAESKGWLHRYGDQ-EVSQFRG--- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 163 gtfAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEAsqgrerrlVATDEQPPKARPDKIPGLKPaFREG 242
Cdd:PRK07801 161 ---AELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGG--------VTVDEGPRETSLEKMAGLKP-LVEG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 243 GTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEA 322
Cdd:PRK07801 229 GRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDDIDVVEINEA 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1222381029 323 FAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK07801 309 FAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEGGGTANVTIIE 380
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
9-394 |
3.15e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 272.65 E-value: 3.15e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMG-GFLGDLAGFSAAELGAAAIRSSLERA-GLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAAQc 85
Cdd:PRK07851 5 VIVSTARSPIGrAFKGSLKDMRPDDLAAQMVRAALDKVpALDPTDIDDLMLGCGLPGGeQGFNMARVVAVLLGYDFLPG- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMS--------------NAPYLLARARGGYRMGHGQVLDHmfldg 151
Cdd:PRK07851 84 TTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSrfakgnsdslpdtkNPLFAEAQARTAARAEGGAEAWH----- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 152 leDAYERGRL------MGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRerrLVATDEQPp 225
Cdd:PRK07851 159 --DPREDGLLpdvyiaMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLPDGT---VVSTDDGP- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 226 kaRP----DKIPGLKPAFREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQ 301
Cdd:PRK07851 233 --RAgttyEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVEASK 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 302 RLLARIEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASV 381
Cdd:PRK07851 311 QALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTFGLETM 390
|
410
....*....|...
gi 1222381029 382 CIGGGEATAVAIE 394
Cdd:PRK07851 391 CVGGGQGMAMVLE 403
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
9-395 |
8.79e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 271.24 E-value: 8.79e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMG-GFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVL-QAGQGQAPARQAALGAGLSQAAQCT 86
Cdd:PRK07661 5 VIVAGARTPVGkAKKGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMpEAEQGLNMARNIGALAGLPYTVPAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 87 TLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYllararggyrMGHGQVLDHMFLdglEDAYERGRLMGTFA 166
Cdd:PRK07661 85 TINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPM----------MGHVVRPNPRLV---EAAPEYYMGMGHTA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 167 EDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR---------ERRLVATDEQ-PPKARPDKIPGLK 236
Cdd:PRK07661 152 EQVAVKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVTLRTvgennklqeETITFSQDEGvRADTTLEILGKLR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 237 PAFREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDL 316
Cdd:PRK07661 232 PAFNVKGSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGL 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1222381029 317 FEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIEL 395
Cdd:PRK07661 312 FELNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFEL 390
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
9-394 |
9.69e-86 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 265.82 E-value: 9.69e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAAQCTT 87
Cdd:PRK07850 5 VIVEAVRTPIGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGeQSNNITRTAWLHAGLPYHVGATT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYllarargGYRMGHGQVL---DHMFLDgLEDAYERgrlmgt 164
Cdd:PRK07850 85 IDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPL-------GANAGPGRGLprpDSWDID-MPNQFEA------ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 165 fAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR-------ERRLVATDEQPPKARPDKIPGLKP 237
Cdd:PRK07850 151 -AERIAKRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDeegqptgETRLVTRDQGLRDTTMEGLAGLKP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 238 AfREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLF 317
Cdd:PRK07850 230 V-LEGGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLV 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 318 EINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK07850 309 EINEAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGGALSTGTIIE 385
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
5-394 |
2.31e-84 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 262.35 E-value: 2.31e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 5 LDPVVIVSAVRTPMGGFL------GDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQA-PARQAALGA 77
Cdd:PRK06445 1 LEDVYLVDFARTAFSRFRpkdpqkDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENWLyGGRHPIFLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 78 GLSQAAQCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPyllararggyrMGHGQVLD-HM-FLdgLEDA 155
Cdd:PRK06445 81 RLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTP-----------MGDNPHIEpNPkLL--TDPK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 156 YER-----GRLMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDEQppkARPD 230
Cdd:PRK06445 148 YIEydlttGYVMGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEVEGKKKVVDVDQS---VRPD 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 231 ----KIPGLKPAFREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLAR 306
Cdd:PRK06445 225 tsleKLAKLPPAFKPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 307 IEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGG 386
Cdd:PRK06445 305 AGLSVKDIDLWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCVGGG 384
|
....*...
gi 1222381029 387 EATAVAIE 394
Cdd:PRK06445 385 QGGAVVLE 392
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
8-394 |
1.24e-83 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 260.28 E-value: 1.24e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAE-LGAAAIRSSLER-AGLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAAQ 84
Cdd:PRK08947 4 VVIVDAIRTPMGRSKGGAFRNVRAEdLSAHLMRSLLARnPALDPAEIDDIIWGCVQQTLeQGFNIARNAALLAGIPHSVP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 85 CTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPyllararggyrMGHGqvLDHMFLDGLEDAYERGrLMGT 164
Cdd:PRK08947 84 AVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVP-----------MNHG--VDFHPGLSKNVAKAAG-MMGL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 165 FAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEA--SQGReRRLVATDEQ-PPKARPDKIPGLKPAFR- 240
Cdd:PRK08947 150 TAEMLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEGhdADGV-LKLFDYDEViRPETTVEALAALRPAFDp 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 241 EGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEIN 320
Cdd:PRK08947 229 VNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELN 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 321 EAFAVVPMVAMRELGI---AHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK08947 309 EAFAAQSLPCLKDLGLldkMDEKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLGQGIATVFE 385
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-394 |
5.11e-83 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 259.16 E-value: 5.11e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 1 MNQHLDPVVIVSAVRTPMG-GFLGDLAGFSAAELGAAAIRSSLERA-GLAAEAVDTVLMGCVL-QAGQGQAPARQAALGA 77
Cdd:PRK09052 1 MSKQLQDAYIVAATRTPVGkAPRGMFKNTRPDDLLAHVLRSAVAQVpGLDPKLIEDAIVGCAMpEAEQGLNVARIGALLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 78 GLSQAAQCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYllararggyrMGHGQVLDHMFLDGLED--- 154
Cdd:PRK09052 81 GLPNSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPM----------MGNKPSMSPAIFARDENvgi 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 155 AYErgrlMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR----------ERRLVATDEQP 224
Cdd:PRK09052 151 AYG----MGLTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEITERFpdlatgevdvKTRTVDLDEGP 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 225 -PKARPDKIPGLKPAFREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRL 303
Cdd:PRK09052 227 rADTSLEGLAKLKPVFANKGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 304 LARIEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCI 383
Cdd:PRK09052 307 LKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMCV 386
|
410
....*....|.
gi 1222381029 384 GGGEATAVAIE 394
Cdd:PRK09052 387 GTGMGAAGIFE 397
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
10-394 |
6.72e-83 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 258.51 E-value: 6.72e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 10 IVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAAQCTTL 88
Cdd:PRK06504 6 IVAAARTAGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGeQATNVARNAVLASKLPESVPGTSI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 89 NKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLArARGGYRMGHGqvldHMFLDGLEDAY---ERGRLMGtf 165
Cdd:PRK06504 86 DRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSP-STLPAKNGLG----HYKSPGMEERYpgiQFSQFTG-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 166 AEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQ--GRERRLVATDEQPPKARPDKIPGLKPaFREGG 243
Cdd:PRK06504 159 AEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRadGSGEMHTVDEGIRFDATLEGIAGVKL-IAEGG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 244 TVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAF 323
Cdd:PRK06504 238 RLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDLYEVNEAF 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1222381029 324 AVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK06504 318 ASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMCEGGGMANVTIVE 388
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
10-394 |
2.54e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 254.81 E-value: 2.54e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 10 IVSAVRTPMGGFL--GDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAAQCT 86
Cdd:PRK08242 6 IYDAVRTPRGKGKkdGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGdQGADIARTAVLAAGLPETVPGV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 87 TLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPylLARARGGYRMGHGQVLDHMFLDgledayergrlMGTFA 166
Cdd:PRK08242 86 QINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVP--MGSDGGAWAMDPSTNFPTYFVP-----------QGISA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 167 EDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRErrLVATDEQP-PKARPDKIPGLKPAFREGGTV 245
Cdd:PRK08242 153 DLIATKYGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDQNGLT--ILDHDEHMrPGTTMESLAKLKPSFAMMGEM 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 246 ---------------------TAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLL 304
Cdd:PRK08242 231 ggfdavalqkypeverinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKAL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 305 ARIEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIG 384
Cdd:PRK08242 311 AKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITLCVG 390
|
410
....*....|
gi 1222381029 385 GGEATAVAIE 394
Cdd:PRK08242 391 GGMGIATIIE 400
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
7-394 |
4.75e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 249.55 E-value: 4.75e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 7 PVVIVSAVRTPmggFLGDLAG---FSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAA 83
Cdd:PRK08170 4 PVYIVDGARTP---FLKARGGpgpFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEANIARVVALRLGCGEKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 84 QCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARA-----RGGYRM-GHGQVLDHMF--------- 148
Cdd:PRK08170 81 PAWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLLFSEKmvrwlAGWYAAkSIGQKLAALGklrpsylap 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 149 ----LDGLEDAYErGRLMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFAsEIVAVEASQGRerRLVATDEQP 224
Cdd:PRK08170 161 viglLRGLTDPVV-GLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLK-EVVPLFDRDGK--FYDHDDGVR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 225 PKARPDKIPGLKPAF-REGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRL 303
Cdd:PRK08170 237 PDSSMEKLAKLKPFFdRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPVHAATPL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 304 LARIEWTLETVDLFEINEAFAVVPMVAMR----------ELGIAH-------DKLNVHGGACALGHPIGASGARILVTLL 366
Cdd:PRK08170 317 LQRHGLTLEDLDLWEINEAFAAQVLACLAawadeeycreQLGLDGalgeldrERLNVDGGAIALGHPVGASGARIVLHLL 396
|
410 420
....*....|....*....|....*...
gi 1222381029 367 AALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK08170 397 HALKRRGTKRGIAAICIGGGQGGAMLLE 424
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
10-394 |
2.74e-78 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 247.00 E-value: 2.74e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 10 IVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQ-GQAPARQAALGAGLSQAAQCTTL 88
Cdd:PRK08131 6 IYDGLRSPFGRHAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEdSRNVARNALLLAGLPVTVPGQTV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 89 NKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARARGGYRMgHGQVLDHM----FLDGLEDAYERGRLMGT 164
Cdd:PRK08131 86 NRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPFVMGKAESAFSR-DAKVFDTTigarFPNPKIVAQYGNDSMPE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 165 FAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGR--ERRLVATDEQP-PKARPDKIPGLKPAFrE 241
Cdd:PRK08131 165 TGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGRklPPKLVAEDEHPrPSSTVEALTKLKPLF-E 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 242 GGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINE 321
Cdd:PRK08131 244 GGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLDDMDIIEINE 323
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1222381029 322 AFAVVPMVAMRELGIAHD--KLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK08131 324 AFASQVLGCLKGLGVDFDdpRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCIGVGQGLAMVIE 398
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
10-394 |
1.83e-75 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 240.06 E-value: 1.83e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 10 IVSAVRTPMG-GFLGD--LAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAAQC 85
Cdd:PRK06025 6 IIDAVRTPRGiGKVGKgaLAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGkQGGDLGRMAALDAGYDIKASG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMS----NAPYLLARARGGYRMGHGqvldHMFLDGLEDAYERGrl 161
Cdd:PRK06025 86 VTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSytaaMAAEDMAAGKPPLGMGSG----NLRLRALHPQSHQG-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 162 mgTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRerRLVATDEQP-PKARPDKIPGLKPAFR 240
Cdd:PRK06025 160 --VCGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVYRDDGS--VALDHEEFPrPQTTAEGLAALKPAFT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 241 --------EGGTV------------------TAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTT 294
Cdd:PRK06025 236 aiadypldDKGTTyrglinqkypdleikhvhHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLN 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 295 APVAAIQRLLARIEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGL 374
Cdd:PRK06025 316 APVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELERRGL 395
|
410 420
....*....|....*....|
gi 1222381029 375 KRGMASVCIGGGEATAVAIE 394
Cdd:PRK06025 396 KRGLVTMCAAGGMAPAIIIE 415
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
1-394 |
2.06e-73 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 235.81 E-value: 2.06e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 1 MNQHLDPVVIVSAVRTPM-----GGFlgdlAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQA-PARQAA 74
Cdd:PLN02287 41 TTAFGDDVVIVAAYRTPIckakrGGF----KDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRAnECRMAA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 75 LGAGLSQAAQCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSnapyllararggyrmghgqvLDHMFLDG--- 151
Cdd:PLN02287 117 FYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMT--------------------TNPMAWEGgvn 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 152 -----LEDAYERGRLMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAV-----EASQGRERRLV--A 219
Cdd:PLN02287 177 prvesFSQAQDCLLPMGITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVhtkivDPKTGEEKPIVisV 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 220 TDEQPPKARPDKIPGLKPAFREGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAA 299
Cdd:PLN02287 257 DDGIRPNTTLADLAKLKPVFKKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVA 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 300 IQRLLARIEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRG--LKRG 377
Cdd:PLN02287 337 IPAAVKAAGLELDDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGkdCRFG 416
|
410
....*....|....*..
gi 1222381029 378 MASVCIGGGEATAVAIE 394
Cdd:PLN02287 417 VVSMCIGTGMGAAAVFE 433
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
9-394 |
1.02e-72 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 231.19 E-value: 1.02e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMGGFLGDLAGFSAAELGAAAIR---SSLERAglaaeaVDTVLMGCVLqaGQGQAPARQAALGAGLSQAAQC 85
Cdd:PRK06690 4 VIVEAKRTPIGKKNGMLKDYEVQQLAAPLLTflsKGMERE------IDDVILGNVV--GPGGNVARLSALEAGLGLHIPG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLlARARggyrmghgqvldhMFLDGLEDAYergrlMGTF 165
Cdd:PRK06690 76 VTIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQ-NRAR-------------FSPETIGDPD-----MGVA 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 166 AEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEAsqgrerrlvATDEQPPKARPDK--IPGLKPAFREGG 243
Cdd:PRK06690 137 AEYVAERYNITREMQDEYACLSYKRTLQALEKGYIHEEILSFNG---------LLDESIKKEMNYEriIKRTKPAFLHNG 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 244 TVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAF 323
Cdd:PRK06690 208 TVTAGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAF 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1222381029 324 AVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK06690 288 ASKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLFE 358
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
9-390 |
6.30e-72 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 230.43 E-value: 6.30e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 9 VIVSAVRTPMG----GFLGDLAGfsaAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAG-QGQAPARQAALGAGLSQAA 83
Cdd:PRK07108 5 VIVSTARTPLAkswrGAFNMTHG---ATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGaTGANIARQIALRAGLPVTV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 84 QCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLARarggyrmghgqvldHMFLDG--LEDAYERGRL 161
Cdd:PRK07108 82 PGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCVQNEMNR--------------HMLREGwlVEHKPEIYWS 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 162 MGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQG-----------RERRLVATDEQPPKARPD 230
Cdd:PRK07108 148 MLQTAENVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTAGvadkatgrlftKEVTVSADEGIRPDTTLE 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 231 KIPGLKPAFrEGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWT 310
Cdd:PRK07108 228 GVSKIRSAL-PGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLK 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 311 LETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATA 390
Cdd:PRK07108 307 VDDIDLWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAA 386
|
|
| fadA |
TIGR02445 |
fatty oxidation complex, beta subunit FadA; This subunit of the FadBA complex has acetyl-CoA ... |
8-394 |
3.00e-70 |
|
fatty oxidation complex, beta subunit FadA; This subunit of the FadBA complex has acetyl-CoA C-acyltransferase (EC 2.3.1.16) activity, and is also known as beta-ketothiolase and fatty oxidation complex, beta subunit. This protein is almost always located adjacent to FadB (TIGR02437). The FadBA complex is the major complex active for beta-oxidation of fatty acids in E. coli. [Fatty acid and phospholipid metabolism, Degradation]
Pssm-ID: 131498 Cd Length: 385 Bit Score: 225.59 E-value: 3.00e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 8 VVIVSAVRTPMGGFLGDLAGFSAAE-LGAAAIRSSLER-AGLAAEAVDTVLMGCVLQA-GQGQAPARQAALGAGLSQAAQ 84
Cdd:TIGR02445 2 VVIVDFGRTPMGRSKGGAFRNTRAEdLSAHLMSKLLARnPKVDPAEVEDIYWGCVQQTlEQGFNIARNAALLAQIPHTSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 85 CTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPyllararggyrMGHGQVLD-HMFLDgledAYERGRLMG 163
Cdd:TIGR02445 82 AVTVNRLCGSSMQALHDAARAIMTGDADVCLVGGVEHMGHVP-----------MMHGVDFHpGMSLH----VAKAAGMMG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 164 TFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVE--ASQGRERRLVATDEQPPKARPDKIPGLKPAFR- 240
Cdd:TIGR02445 147 LTAEMLGKMHGISREQQDAFAARSHARAHAATQEGKFKNEIIPTQghDADGFLKQFDYDEVIRPETTVESLAALRPAFDp 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 241 EGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEIN 320
Cdd:TIGR02445 227 KNGTVTAGTSSALSDGASAMLVMSEQRANELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELN 306
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1222381029 321 EAFAVVPMVAMRELGI---AHDKLNVHGGACALGHPIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:TIGR02445 307 EAFAAQALPCLKDLGLldkMDEKVNLNGGAIALGHPLGCSGARISTTLLNLMEQKDATFGLATMCIGLGQGIATVFE 383
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
6-394 |
2.14e-56 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 190.97 E-value: 2.14e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 6 DPVVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQC 85
Cdd:PRK08963 5 DRIAIVSGLRTPFAKQATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 86 TTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPYLLAR--ARGGYRMGH----GQVLDHMFLDGLED----- 154
Cdd:PRK08963 85 YSVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVSKklARALVDLNKartlGQRLKLFSRLRLRDllpvp 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 155 ----AYERGRLMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRErrlvaTDEQPPKARPD 230
Cdd:PRK08963 165 pavaEYSTGLRMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMTAHVPPYKQ-----PLEEDNNIRGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 231 KIPG----LKPAF-REGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAP-NLFTTAPVAAIQRLL 304
Cdd:PRK08963 240 STLEdyakLRPAFdRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVwQDMLLGPAYATPLAL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 305 ARIEWTLETVDLFEINEAFAV-----VPMVAMRE-----LG-------IAHDKLNVHGGACALGHPIGASGARILVTLLA 367
Cdd:PRK08963 320 ERAGLTLADLTLIDMHEAFAAqtlanLQMFASERfarekLGrsqaigeVDMSKFNVLGGSIAYGHPFAATGARMITQTLH 399
|
410 420
....*....|....*....|....*..
gi 1222381029 368 ALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK08963 400 ELRRRGGGLGLTTACAAGGLGAAMVLE 426
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
11-394 |
1.15e-53 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 182.69 E-value: 1.15e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 11 VSAVRTPMGGFLGDLAGFS---AAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQCTT 87
Cdd:cd00826 1 AGAAMTAFGKFGGENGADAndlAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 88 LNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNApyllarARGGYRMGHgqvldhmfLDGLEDAYErgrlmgtfae 167
Cdd:cd00826 81 MNNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETS------AENNAKEKH--------IDVLINKYG---------- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 168 dcaqqyrfSREEQDAYALESLRRAQQAIEQGSFASEIVAVEASQGRERRLVATDE---QPPKARPDKIPGLKPAFREGGT 244
Cdd:cd00826 137 --------MRACPDAFALAGQAGAEAAEKDGRFKDEFAKFGVKGRKGDIHSDADEyiqFGDEASLDEIAKLRPAFDKEDF 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 245 VTAANASSISDGAAALLLMRLSEAQE-------RGLKPLARIVGHAGHAQAPNLFT----TAPVAAIQRLLARIEWTLET 313
Cdd:cd00826 209 LTAGNACGLNDGAAAAILMSEAEAQKhglqskaREIQALEMITDMASTFEDKKVIKmvggDGPIEAARKALEKAGLGIGD 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 314 VDLFEINEAFAVVPMVAMRELGIAHDK------------------LNVHGGACALGHPIGASGARILVTLLAALQQRGLK 375
Cdd:cd00826 289 LDLIEAHDAFAANACATNEALGLCPEGqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEAGK 368
|
410 420
....*....|....*....|....
gi 1222381029 376 R-----GMASVCIGGGEATAVAIE 394
Cdd:cd00826 369 RqgagaGLALLCIGGGGGAAMCIE 392
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
1-394 |
7.89e-50 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 173.55 E-value: 7.89e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 1 MNQHLDPVVIVSAVRTPMGGFLGDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLS 80
Cdd:PRK09268 2 TMPTVRRVAILGGNRIPFARSNGAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSALS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 81 QAAQCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAP---------YLLARARGGYRMGHGQVLDHMFLDG 151
Cdd:PRK09268 82 PYTPAYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSDAPiavneglrkILLELNRAKTTGDRLKALGKLRPKH 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 152 LEDAYER------GRLMGTFAEDCAQQYRFSREEQDAYALESLRRAQQAIEQGSFASEIVAVeasqgreRRLVATDEQPP 225
Cdd:PRK09268 162 LAPEIPRngeprtGLSMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPF-------LGLTRDNNLRP 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 226 KARPDKIPGLKPAF--REGGTVTAANASSISDGAAALLLMRLSEAQERGLKPLARIVghAGHAQAPNLFT------TAPV 297
Cdd:PRK09268 235 DSSLEKLAKLKPVFgkGGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLV--DAETAAVDFVHgkegllMAPA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 298 AAIQRLLARIEWTLETVDLFEINEAFAVVPMVAMR----------ELG-------IAHDKLNVHGGACALGHPIGASGAR 360
Cdd:PRK09268 313 YAVPRLLARNGLTLQDFDFYEIHEAFASQVLATLKawedeeycreRLGldaplgsIDRSKLNVNGSSLAAGHPFAATGGR 392
|
410 420 430
....*....|....*....|....*....|....
gi 1222381029 361 ILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:PRK09268 393 IVATLAKLLAEKGSGRGLISICAAGGQGVTAILE 426
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
273-394 |
1.09e-44 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 150.49 E-value: 1.09e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 273 LKPLARIVGHAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLFEINEAFAVVPMVAMRELGIAHDKLNVHGGACALGH 352
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1222381029 353 PIGASGARILVTLLAALQQRGLKRGMASVCIGGGEATAVAIE 394
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIE 122
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
23-393 |
3.44e-16 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 79.23 E-value: 3.44e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 23 GDLAGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSqAAQCTTLNKMCGSGMQALMLG 102
Cdd:cd00829 9 GRRSDRSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLL-GKPATRVEAAGASGSAAVRAA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 103 HDQLLAGSADVLVAGGMESMSNAPY-LLARARGGYRMGHGQVLDHMFLDGLEDAYERGRLMGTFAEDCAQQYRFSREeQD 181
Cdd:cd00829 88 AAAIASGLADVVLVVGAEKMSDVPTgDEAGGRASDLEWEGPEPPGGLTPPALYALAARRYMHRYGTTREDLAKVAVK-NH 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 182 AYALESlRRAQqaieqgsFASEIVA--VEASqgrerRLVAtdeqPPkarpdkipglkpafreggtVTAANASSISDGAAA 259
Cdd:cd00829 167 RNAARN-PYAQ-------FRKPITVedVLNS-----RMIA----DP-------------------LRLLDCCPVSDGAAA 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 260 LLLMRLSEAQERGLKPlARIVGHAGHAQAPNLFT-------TAPVAAIQRLLARIEWTLETVDLFEINEAFAVVPMVAMR 332
Cdd:cd00829 211 VVLASEERARELTDRP-VWILGVGAASDTPSLSErddflslDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALE 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 333 ELGIAHD------------------KLNVHGGACALGHPIGASGARILVTLL-------AALQQRGLKRGMASVcIGGGE 387
Cdd:cd00829 290 DLGFCEKgeggklvregdtaiggdlPVNTSGGLLSKGHPLGATGLAQAVEAVrqlrgeaGARQVPGARVGLAHN-IGGTG 368
|
....*.
gi 1222381029 388 ATAVAI 393
Cdd:cd00829 369 SAAVVT 374
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
247-393 |
1.05e-13 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 70.55 E-value: 1.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 247 AANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFT----TAPVAAIQRLLARIEWTLETVDLFEINEA 322
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASMVPavsgEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 323 FAVVPMVAMRELGIAHDK---LNVHGGACALGHPIGASGARILVTLLAALQ-------QRGLKRGMASVCIGGGEATAVA 392
Cdd:cd00327 174 GTPIGDAVELALGLDPDGvrsPAVSATLIMTGHPLGAAGLAILDELLLMLEhefipptPREPRTVLLLGFGLGGTNAAVV 253
|
.
gi 1222381029 393 I 393
Cdd:cd00327 254 L 254
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
32-392 |
1.21e-08 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 56.44 E-value: 1.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 32 ELGAAAIRSSLERAGLAAEA--VDTVLMGCVL-QAGQGQAPARQAALGAGLSQAAQCTTLNK-------MCGSGMQALML 101
Cdd:PTZ00455 50 ELLATAIQGTLENTGLDGKAalVDKVVVGNFLgELFSSQGHLGPAAVGSLGQSGASNALLYKpamrvegACASGGLAVQS 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 102 GHDQLLAGSADVLVAGGMESMSNAPyllARARGGY--RMGHgqvldhmfldgledaYERGRLMGTFAEDC--AQQYRFSR 177
Cdd:PTZ00455 130 AWEALLAGTSDIALVVGVEVQTTVS---ARVGGDYlaRAAD---------------YRRQRKLDDFTFPClfAKRMKYIQ 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 178 EEQDAYALESLRRAQQAIEQGSfASEIVAVEASQGRERRLVATDEQPPKARPDkiPGLKPAFReggtvtAANASSISDGA 257
Cdd:PTZ00455 192 EHGHFTMEDTARVAAKAYANGN-KNPLAHMHTRKLSLEFCTGASDKNPKFLGN--ETYKPFLR------MTDCSQVSDGG 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 258 AALLLMRLSEAQERGLKPL-ARIVGHAGHAQAP-NLFTTAP--------VAAIQRLLARIEWTLETVDLFEINEAFAVVP 327
Cdd:PTZ00455 263 AGLVLASEEGLQKMGLSPNdSRLVEIKSLACASgNLYEDPPdatrmftsRAAAQKALSMAGVKPSDLQVAEVHDCFTIAE 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 328 MVAMRELGIA---HDK---------------LNVHGGACALGHPIGASGA-------RILVTLLAALQQRGLKRGMASVC 382
Cdd:PTZ00455 343 LLMYEALGIAeygHAKdlirngatalegripVNTGGGLLSFGHPVGATGVkqimevyRQMKGQCGEYQMKNIPALGATLN 422
|
410
....*....|
gi 1222381029 383 IGGGEATAVA 392
Cdd:PTZ00455 423 MGGDDKTAVS 432
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
18-392 |
7.54e-08 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 53.92 E-value: 7.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 18 MGGFLGDLA------GFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCV---LQAGQGQAPARQAALGAGLS-------Q 81
Cdd:PRK06289 8 LGGYQSDFArnwtkeGRDFADLTREVVDGTLAAAGVDADDIEVVHVGNFfgeLFAGQGHLGAMPATVHPALWgvpasrhE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 82 AAqcttlnkmCGSGMQALMLGHDQLLAGSADVLVAGGMESMSNAPyllaRARGGYRMGHGQVLDHmflDGLEDAYERGRL 161
Cdd:PRK06289 88 AA--------CASGSVATLAAMADLRAGRYDVALVVGVELMKTVP----GDVAAEHLGAAAWTGH---EGQDARFPWPSM 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 162 MGTFAEDCAQQYRFSREEqdayalesLRraqqAIEQGSFAseivaveasqgRERRlvatdeqPPKA--RPDKIPglKPAF 239
Cdd:PRK06289 153 FARVADEYDRRYGLDEEH--------LR----AIAEINFA-----------NARR-------NPNAqtRGWAFP--DEAT 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 240 REGGTVTAA--------NASSISDGAAALLLMRLSEAQE-RGLKPLARIVGHaGHAQAPNLFTT-------APV------ 297
Cdd:PRK06289 201 NDDDATNPVvegrlrrqDCSQVTDGGAGVVLASDAYLRDyADARPIPRIKGW-GHRTAPLGLEQkldrsagDPYvlphvr 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 298 AAIQRLLARIEWTLETVDLFEINEAFAVVPMVAMRELGIA------------------HDKLNVHGGACALGHPIGASGA 359
Cdd:PRK06289 280 QAVLDAYRRAGVGLDDLDGFEVHDCFTPSEYLAIDHIGLTgpgeswkaiengeiaiggRLPINPSGGLIGGGHPVGASGV 359
|
410 420 430
....*....|....*....|....*....|....*....
gi 1222381029 360 RIL------VTLLAALQQRGLKRGMASVCIGGGEATAVA 392
Cdd:PRK06289 360 RMLldaakqVTGTAGDYQVEGAKTFGTLNIGGSTTTTVS 398
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
250-391 |
1.35e-06 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 49.90 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 250 ASSISDGAAALLLMRLSEAQERGLKPLaRIVGHAGHAQAPNL-----FTT--APVAAIQRLLARIEWTLETVDLFEINEA 322
Cdd:PRK06064 208 CSPITDGAAAVILASEEKAKEYTDTPV-WIKASGQASDTIALhdrkdFTTldAAVVAAEKAYKMAGIEPKDIDVAEVHDC 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 323 FAVVPMVAMRELGIAHD----KL--------------NVHGGACALGHPIGASGARILVTLLAALQQRGLK--------- 375
Cdd:PRK06064 287 FTIAEILAYEDLGFAKKgeggKLaregqtyiggdipvNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAEKgrqqvigag 366
|
170
....*....|....*.
gi 1222381029 376 RGMASvCIGGGEATAV 391
Cdd:PRK06064 367 YGLTH-NVGGTGHTAV 381
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
251-376 |
5.14e-06 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 48.10 E-value: 5.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 251 SSISDGAAALLLMRLSEAQERG------LKPLARIVGHAGHAQAPNL-FTTAP--VAAIQRLL--ARIEWTLETVDLFEI 319
Cdd:PRK06157 214 CGVSDGAAAAIVTTPEIARALGkkdpvyVKALQLAVSNGWELQYNGWdGSYFPttRIAARKAYreAGITDPREELSMAEV 293
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1222381029 320 NEAFAVVPMVAMRELGIA------HDKL------------NVHGGACALGHPIGASGARILVTLLAALQQRGLKR 376
Cdd:PRK06157 294 HDCFSITELVTMEDLGLSergqawRDVLdgffdadgglpcQIDGGLKCFGHPIGASGLRMLYEMYLQLLGRAGER 368
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
29-358 |
1.17e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 47.15 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 29 SAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPARQAALGAGLSQAAQcTTLNKMCGSGMQALMLGHDQLLA 108
Cdd:PRK12578 20 SVQELAWESIKEALNDAGVSQTDIELVVVGSTAYRGIELYPAPIVAEYSGLTGKVP-LRVEAMCATGLAASLTAYTAVAS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 109 GSADVLVAGGMESMSNAPYLLARARGGyRMGHGQVLDHMFLDGLEDAYE--RGRLMGTFAedcaqqyrfSREEQDAYALE 186
Cdd:PRK12578 99 GLVDMAIAVGVDKMTEVDTSTSLAIGG-RGGNYQWEYHFYGTTFPTYYAlyATRHMAVYG---------TTEEQMALVSV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 187 SLRRAQQAIEQGSFASEIvaveasqgrerrlvaTDEQPPKARPDKIPglkpafreggtVTAANASSISDGAAALLLMRLS 266
Cdd:PRK12578 169 KAHKYGAMNPKAHFQKPV---------------TVEEVLKSRAISWP-----------IKLLDSCPISDGSATAIFASEE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 267 EAQERGLKPLARIVGhAGHAQapnlfTTAPVAaiqrllARIEW-------------------TLETVDLFEINEAFAVVP 327
Cdd:PRK12578 223 KVKELKIDSPVWITG-IGYAN-----DYAYVA------RRGEWvgfkatqlaarqaynmakvTPNDIEVATVHDAFTIAE 290
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1222381029 328 MVAMRELGIAH-------------DK-----LNVHGGACALGHPIGASG 358
Cdd:PRK12578 291 IMGYEDLGFTEkgkggkfieegqsEKggkvgVNLFGGLKAKGHPLGATG 339
|
|
| PRK08257 |
PRK08257 |
acetyl-CoA acetyltransferase; Validated |
249-346 |
1.46e-05 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 236204 [Multi-domain] Cd Length: 498 Bit Score: 46.83 E-value: 1.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 249 NASSISDGAAALLLMRLSEAQERGLkPLARIVGHAGHAQA---------PNLFTTAP-VAAIQRLLARIEWTLETVDLFE 318
Cdd:PRK08257 238 NANDMVDQGAAVLLTSVAKARRLGV-PEDRWVYLHGGADAhdpydilerPDLHRSPAiRAAGRRALALAGLGIDDIDAFD 316
|
90 100 110
....*....|....*....|....*....|.
gi 1222381029 319 INEAFAVVPMVAMRELGIAHDK---LNVHGG 346
Cdd:PRK08257 317 LYSCFPSAVQVAARELGLDLDDprpLTVTGG 347
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
251-378 |
2.44e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 46.09 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 251 SSISDGAAALLLmrlseAQERGLKPLARIVGHAGHAQAPNLFT---------TAPVAAIQRLLARIEWTLETVDLFEINE 321
Cdd:PRK07516 213 SLVSDGAAALVL-----ADAETARALQRAVRFRARAHVNDFLPlsrrdplafEGPRRAWQRALAQAGVTLDDLSFVETHD 287
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1222381029 322 AFAVVPMVAMRELGIAHD----------------KL--NVHGGACALGHPIGASGARILVtlLAALQQRGLKRGM 378
Cdd:PRK07516 288 CFTIAELIEYEAMGLAPPgqgarairegwtakdgKLpvNPSGGLKAKGHPIGATGVSMHV--LAAMQLTGEAGGM 360
|
|
| PRK06059 |
PRK06059 |
lipid-transfer protein; Provisional |
6-122 |
3.13e-05 |
|
lipid-transfer protein; Provisional
Pssm-ID: 180373 [Multi-domain] Cd Length: 399 Bit Score: 45.91 E-value: 3.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 6 DPVVIVSAVRTPMGGFlgdlaGFSAAELGAAAIRSSLERAGLAAEAVDTVLMGCVLQAGQGQAPArqaalGAGLSQA--- 82
Cdd:PRK06059 4 EPVYILGAGMHPWGKW-----GRDFVEYGVVAARAALADAGLDWRDVQLVVGADTIRNGYPGFVA-----GATFAQAlgw 73
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1222381029 83 --AQCTTLNKMCGSGMQALMLGHDQLLAGSADVLVAGGMESM 122
Cdd:PRK06059 74 ngAPVSSSYAACASGSQALQSARAQILAGLCDVALVVGADTT 115
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
253-359 |
1.28e-03 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 40.46 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 253 ISDGAAALLLMRLSEAQERGLKPLARIVGH-----AGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLfeIN------- 320
Cdd:COG0304 229 LGEGAGVLVLEELEHAKARGAKIYAEVVGYgassdAYHITAPAPDGEGAARAMRAALKDAGLSPEDIDY--INahgtstp 306
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1222381029 321 -----EAfavvpmVAMRE-LGIAHDKLNVHGGACALGHPIGASGA 359
Cdd:COG0304 307 lgdaaET------KAIKRvFGDHAYKVPVSSTKSMTGHLLGAAGA 345
|
|
| PKS |
cd00833 |
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different ... |
247-372 |
1.48e-03 |
|
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.
Pssm-ID: 238429 [Multi-domain] Cd Length: 421 Bit Score: 40.62 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 247 AANASSISDGAAALLLMRLSEAQERGLKPLARI----VGHAGHAQ---APNlfTTAPVAAIQRLLARIEWTLETVDLFE- 318
Cdd:cd00833 227 DADGYVRGEGVGVVVLKRLSDALRDGDRIYAVIrgsaVNQDGRTKgitAPS--GEAQAALIRRAYARAGVDPSDIDYVEa 304
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1222381029 319 ---------------INEAFAvvpmvamrelgiahdKLNVHGGACAL-------GHPIGASGARILVTLLAALQQR 372
Cdd:cd00833 305 hgtgtplgdpieveaLAKVFG---------------GSRSADQPLLIgsvksniGHLEAAAGLAGLIKVVLALEHG 365
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
29-118 |
2.51e-03 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 39.72 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 29 SAAELGAAAIRSSLERAGLAAEAVDTVLMGC--VLQAGQGQAPARQAALGAglsQAAQCTTLNKMCGSGMQALMLGHDQL 106
Cdd:cd00827 47 DVPTMAVEAARRALERAGIDPDDIGLLIVATesPIDKGKSAATYLAELLGL---TNAEAFDLKQACYGGTAALQLAANLV 123
|
90
....*....|...
gi 1222381029 107 LAGS-ADVLVAGG 118
Cdd:cd00827 124 ESGPwRYALVVAS 136
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
252-315 |
2.71e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 39.44 E-value: 2.71e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1222381029 252 SISDGAAALLLMRLSEAQERGLKPLARIVGH-----AGHAQAPNLFTTAPVAAIQRLLARIEWTLETVD 315
Cdd:cd00834 228 VLGEGAGVLVLESLEHAKARGAKIYAEILGYgassdAYHITAPDPDGEGAARAMRAALADAGLSPEDID 296
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
255-372 |
3.50e-03 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 39.26 E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 255 DGAAALLLMRLSEAQERGLKPLARIVG-----HAGHAQAPNLFTTAPVAAIQRLLARIEWTLETVDLF-------EINEA 322
Cdd:PRK05952 210 EGGAILVLESAELAQKRGAKIYGQILGfgltcDAYHMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIhahgtatRLNDQ 289
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1222381029 323 F-AVVpmvamrelgIAH---DKLNVHGGACALGHPIGASGA-RILVTLLAALQQR 372
Cdd:PRK05952 290 ReANL---------IQAlfpHRVAVSSTKGATGHTLGASGAlGVAFSLLALRHQQ 335
|
|
| PRK06816 |
PRK06816 |
StlD/DarB family beta-ketosynthase; |
28-123 |
4.31e-03 |
|
StlD/DarB family beta-ketosynthase;
Pssm-ID: 235866 Cd Length: 378 Bit Score: 39.12 E-value: 4.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 28 FSAAELGAAAIRSSLERAGLAAEAVDtvlmgcVLQAGQ--------GQAPARQAALGAGlsqAAQCTTLNKMCGSGMQAL 99
Cdd:PRK06816 61 HSNAQMAAEAIRDLLDDAGFSLGDIE------LLACGTsqpdqlmpGHASMVHGELGAP---PIEVVSSAGVCAAGMMAL 131
|
90 100
....*....|....*....|....
gi 1222381029 100 MLGHDQLLAGSADVLVAGGMESMS 123
Cdd:PRK06816 132 KYAYLSVKAGESRNAVATASELAS 155
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
33-122 |
8.54e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 37.96 E-value: 8.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 33 LGAAAIRSSLERAGLAAEAVDTVLMGCVLqagqGQAPARQAAL-GAGLSqAAQCTTLNKMCGSGMQALMLGHDQLLAGSA 111
Cdd:PRK08256 25 MAAEAGRAALADAGIDYDAVQQAYVGYVY----GDSTSGQRALyEVGMT-GIPIVNVNNNCSTGSTALFLARQAVRSGAA 99
|
90
....*....|.
gi 1222381029 112 DVLVAGGMESM 122
Cdd:PRK08256 100 DCALALGFEQM 110
|
|
| PRK14691 |
PRK14691 |
3-oxoacyl-(acyl carrier protein) synthase II; Provisional |
246-371 |
8.71e-03 |
|
3-oxoacyl-(acyl carrier protein) synthase II; Provisional
Pssm-ID: 173154 [Multi-domain] Cd Length: 342 Bit Score: 37.79 E-value: 8.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1222381029 246 TAANASSISDGAAALLLMRLSEAQERGLKPLARIVGHAGHAQAPNLFTTA-----PVAAIQRLLARIEWTLETV------ 314
Cdd:PRK14691 153 TARDGFVMGEGAGLLIIEELEHALARGAKPLAEIVGYGTSADAYHMTSGAedgdgAYRAMKIALRQAGITPEQVqhlnah 232
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1222381029 315 -------DLFEINeafavvpmvAMRELGIAHDKLNVHGGACALGHPIGASGA-RILVTLLAALQQ 371
Cdd:PRK14691 233 atstpvgDLGEIN---------AIKHLFGESNALAITSTKSATGHLLGAAGGlETIFTVLALRDQ 288
|
|
| |
