|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-429 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 879.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDGE-DRYLGKGVQKAVDNVNNIIAETLV 79
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDkSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 80 GVDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPI 159
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 160 AFQEFMILPVGAPSFKEALRWGTEVFHALAKILADRGLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLG 239
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 240 FDCAASEFYENGVYDytkFEGEGaAKRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLV 319
Cdd:COG0148 241 LDVAASEFYKDGKYH---LKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 320 TNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTD 399
Cdd:COG0148 317 TNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSE 396
|
410 420 430
....*....|....*....|....*....|
gi 1224054089 400 RVAKYNQLLRIEDQLGDLAVYKGRDTFYNL 429
Cdd:COG0148 397 RVAKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-430 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 852.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDGE-DRYLGKGVQKAVDNVNNIIAETLV 79
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDkSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 80 GVDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPI 159
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 160 AFQEFMILPVGAPSFKEALRWGTEVFHALAKILADRGLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLG 239
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 240 FDCAASEFYENGVYDytkFEGEGaakRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLV 319
Cdd:PRK00077 241 LDCAASEFYKDGKYV---LEGEG---LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 320 TNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTD 399
Cdd:PRK00077 315 TNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSE 394
|
410 420 430
....*....|....*....|....*....|.
gi 1224054089 400 RVAKYNQLLRIEDQLGDLAVYKGRDTFYNLK 430
Cdd:PRK00077 395 RIAKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-413 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 735.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 6 DVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDG-EDRYLGKGVQKAVDNVNNIIAETLVGVDVT 84
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGdKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 85 NQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPIAFQEF 164
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 165 MILPVGAPSFKEALRWGTEVFHALAKILADRG--LETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLGFDC 242
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 243 AASEFYENGVYDYTKFEGEgaaKRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLVTNT 322
Cdd:cd03313 241 AASEFYDEGKYVYDSDEGK---KLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 323 EKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTDRVA 402
Cdd:cd03313 318 ERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTA 397
|
410
....*....|.
gi 1224054089 403 KYNQLLRIEDQ 413
Cdd:cd03313 398 KYNQLLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-429 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 724.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 4 ITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDGE-DRYLGKGVQKAVDNVNNIIAETLVGVD 82
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDkKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 83 VTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPIAFQ 162
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 163 EFMILPVGAPSFKEALRWGTEVFHALAKILADRGLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLGFDC 242
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 243 AASEFYENGVYDYTkFEGEGAAKrTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLVTNT 322
Cdd:TIGR01060 241 AASEFYDEEDGKYV-YKGENKQL-TSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 323 EKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTDRVA 402
Cdd:TIGR01060 319 EILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIA 398
|
410 420
....*....|....*....|....*..
gi 1224054089 403 KYNQLLRIEDQLGDLAVYKGRDTFYNL 429
Cdd:TIGR01060 399 KYNQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
138-429 |
2.39e-151 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 430.75 E-value: 2.39e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 138 TKELPVPMMNIVNGGSHSSAPIAFQEFMILPVGAPSFKEALRWGTEVFHALAKILADRG--LETTVGDEGGFAPKFEGTE 215
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 216 DGVETILEAIKAAGLTPgeDVLLGFDCAASEFY--ENGVYDYtKFEGE---GAAKRTSSEQVDYLEELVNKYPIISIEDG 290
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDL-DFKGEksdKSKKLTSAQLADLYEELVKKYPIVSIEDP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 291 LDEDDWDGWKELTDRLGDRVQLVGDDLLVTNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRS 370
Cdd:pfam00113 158 FDEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRS 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1224054089 371 GETEDTTISDIAVATNAGQIKTGSLSRTDRVAKYNQLLRIEDQLGDLAVYKGRDTFYNL 429
Cdd:pfam00113 238 GETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-429 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 879.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDGE-DRYLGKGVQKAVDNVNNIIAETLV 79
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDkSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 80 GVDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPI 159
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 160 AFQEFMILPVGAPSFKEALRWGTEVFHALAKILADRGLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLG 239
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 240 FDCAASEFYENGVYDytkFEGEGaAKRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLV 319
Cdd:COG0148 241 LDVAASEFYKDGKYH---LKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 320 TNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTD 399
Cdd:COG0148 317 TNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSE 396
|
410 420 430
....*....|....*....|....*....|
gi 1224054089 400 RVAKYNQLLRIEDQLGDLAVYKGRDTFYNL 429
Cdd:COG0148 397 RVAKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-430 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 852.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDGE-DRYLGKGVQKAVDNVNNIIAETLV 79
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDkSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 80 GVDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPI 159
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 160 AFQEFMILPVGAPSFKEALRWGTEVFHALAKILADRGLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLG 239
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 240 FDCAASEFYENGVYDytkFEGEGaakRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLV 319
Cdd:PRK00077 241 LDCAASEFYKDGKYV---LEGEG---LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 320 TNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTD 399
Cdd:PRK00077 315 TNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSE 394
|
410 420 430
....*....|....*....|....*....|.
gi 1224054089 400 RVAKYNQLLRIEDQLGDLAVYKGRDTFYNLK 430
Cdd:PRK00077 395 RIAKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-413 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 735.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 6 DVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDG-EDRYLGKGVQKAVDNVNNIIAETLVGVDVT 84
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGdKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 85 NQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPIAFQEF 164
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 165 MILPVGAPSFKEALRWGTEVFHALAKILADRG--LETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLGFDC 242
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 243 AASEFYENGVYDYTKFEGEgaaKRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLVTNT 322
Cdd:cd03313 241 AASEFYDEGKYVYDSDEGK---KLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 323 EKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTDRVA 402
Cdd:cd03313 318 ERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTA 397
|
410
....*....|.
gi 1224054089 403 KYNQLLRIEDQ 413
Cdd:cd03313 398 KYNQLLRIEEE 408
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-429 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 724.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 4 ITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDGE-DRYLGKGVQKAVDNVNNIIAETLVGVD 82
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDkKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 83 VTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGSHSSAPIAFQ 162
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 163 EFMILPVGAPSFKEALRWGTEVFHALAKILADRGLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTPGEDVLLGFDC 242
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 243 AASEFYENGVYDYTkFEGEGAAKrTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLVTNT 322
Cdd:TIGR01060 241 AASEFYDEEDGKYV-YKGENKQL-TSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 323 EKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTDRVA 402
Cdd:TIGR01060 319 EILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIA 398
|
410 420
....*....|....*....|....*..
gi 1224054089 403 KYNQLLRIEDQLGDLAVYKGRDTFYNL 429
Cdd:TIGR01060 399 KYNQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-422 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 570.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGAFgRGIVPSGASTGEYEAVELRDG-EDRYLGKGVQKAVDNVNNIIAETLV 79
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGdKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 80 GVDVTNQQLIDRMMIE-LDGTPN-----KGKLGANAILGVSIAVAKAAADHLGISLYHYLG---GFNTKE--LPVPMMNI 148
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAqlaGKPTDKfvLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 149 VNGGSHSSAPIAFQEFMILPVGAPSFKEALRWGTEVFHALAKILADR-GLETT-VGDEGGFAPKFEGTEDGVETILEAIK 226
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDATnVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 227 AAGLTpGEdVLLGFDCAASEFY--ENGVYD--YTKFEGEGAAKRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKEL 302
Cdd:PTZ00081 240 KAGYE-GK-VKICMDVAASEFYdkEKKVYDldFKNPNNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 303 TDRLGDRVQLVGDDLLVTNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIA 382
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1224054089 383 VATNAGQIKTGSLSRTDRVAKYNQLLRIEDQLGDLAVYKG 422
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
|
|
| PLN00191 |
PLN00191 |
enolase |
1-424 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 550.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGAFgRGIVPSGASTGEYEAVELRDGEDRYLGKGVQKAVDNVNNIIAETLVG 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDKDYLGKGVLKAVKNVNEIIAPALIG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 81 VDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLY-HY--LGGFNTKELPVPMMNIVNGGSHSSA 157
Cdd:PLN00191 104 MDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYkHIadLAGNKKLVLPVPAFNVINGGSHAGN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 158 PIAFQEFMILPVGAPSFKEALRWGTEVFHALAKILADR--GLETTVGDEGGFAPKFEGTEDGVETILEAIKAAGLTpgED 235
Cdd:PLN00191 184 KLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT--GK 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 236 VLLGFDCAASEFY-ENGVYD--YTKFEGEGAAKRTSSEQVDYLEELVNKYPIISIEDGLDEDDWDGWKELTDRlgDRVQL 312
Cdd:PLN00191 262 IKIGMDVAASEFYtKDKKYDldFKEENNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDVQI 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 313 VGDDLLVTNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIKT 392
Cdd:PLN00191 340 VGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIKT 419
|
410 420 430
....*....|....*....|....*....|..
gi 1224054089 393 GSLSRTDRVAKYNQLLRIEDQLGDLAVYKGRD 424
Cdd:PLN00191 420 GAPCRSERLAKYNQLLRIEEELGDEAVYAGEN 451
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
138-429 |
2.39e-151 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 430.75 E-value: 2.39e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 138 TKELPVPMMNIVNGGSHSSAPIAFQEFMILPVGAPSFKEALRWGTEVFHALAKILADRG--LETTVGDEGGFAPKFEGTE 215
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 216 DGVETILEAIKAAGLTPgeDVLLGFDCAASEFY--ENGVYDYtKFEGE---GAAKRTSSEQVDYLEELVNKYPIISIEDG 290
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDL-DFKGEksdKSKKLTSAQLADLYEELVKKYPIVSIEDP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 291 LDEDDWDGWKELTDRLGDRVQLVGDDLLVTNTEKLSEAIEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRS 370
Cdd:pfam00113 158 FDEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRS 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1224054089 371 GETEDTTISDIAVATNAGQIKTGSLSRTDRVAKYNQLLRIEDQLGDLAVYKGRDTFYNL 429
Cdd:pfam00113 238 GETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-133 |
2.87e-87 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 261.54 E-value: 2.87e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 4 ITDVYAREVLDSRGNPTVEVEVYTASGAFGRGIVPSGASTGEYEAVELRDG-EDRYLGKGVQKAVDNVNNIIAETLVGVD 82
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGdKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1224054089 83 VTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYL 133
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-416 |
7.91e-23 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 98.72 E-value: 7.91e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 1 MPFITDVYAREVLDSRGNPTVEVEVYTASGaFGRGIVPsgastgeyeaveLRDGEDRYLGKGvQKAVDNVNNIIAETLVG 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAP------------IDENPSLYIAEA-HRAVSEVDEIIGPELIG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 81 VDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVPMMNIVNGGShssapia 160
Cdd:PRK08350 67 FDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAEDEN------- 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 161 FQEFMILpvgapsfkEALRWGTEVFHALAKILAdrglettvgdeggfapkfEGTEDGVETILEAIKAAGLTPGEDVLLGF 240
Cdd:PRK08350 140 FEYYVLV--------RDLMEITDVVDAVNKILE------------------NSKEVSLEGLSKASEKAGDELGLEVALGI 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 241 dcaasefyengvydytkfegegaaKRTSSEQVDYLEELVNKYPIISIEDGLDEddwdgwkELTDRLgdrvqLVGDDLLVT 320
Cdd:PRK08350 194 ------------------------AQKREMETEKVLNLVEDNNIAYIKPIGDE-------ELFLEL-----IAGTHGVFI 237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 321 NTEKLSEA---IEKDISNSILIKVNQIGTLTETFDAIEMAKKAGYTAVISHRSGETEDTTISDIAVATNAGQIktgsLSR 397
Cdd:PRK08350 238 DGEYLFRTrniLDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM----LIH 313
|
410
....*....|....*....
gi 1224054089 398 TDRVAKYNQLLRIEDQLGD 416
Cdd:PRK08350 314 KDSVEKINELNRIAEDLGE 332
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
192-392 |
1.07e-13 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 70.05 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 192 LADRGLETTVGD--EGGFAPKFE--GTEDGVETILEAIkaagltpGEDVLLGFDCaasefyeNGVYDYTkfegegaakrt 267
Cdd:cd00308 54 LAAKALGVPLAEllGGGSRDRVPayGSIERVRAVREAF-------GPDARLAVDA-------NGAWTPK----------- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 268 ssEQVDYLEELvNKYPIISIEDGLDEDDWDGWKELTDRLGdrVQLVGDDLLVTNtEKLSEAIEKDISNSILIKVNQIGTL 347
Cdd:cd00308 109 --EAIRLIRAL-EKYGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESVTTV-DDALEALELGAVDILQIKPTRVGGL 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1224054089 348 TETFDAIEMAKKAGYTAVISHRSGETEDTTIS-DIAVAT-NAGQIKT 392
Cdd:cd00308 183 TESRRAADLAEAFGIRVMVHGTLESSIGTAAAlHLAAALpNDRAIET 229
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
50-414 |
2.87e-11 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 65.28 E-value: 2.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 50 ELRDGEDRYLGKGVQKAVDNVNNIIAETLVGVDVTNQQLIDRMMIELDGTPNKGKLGANAILGVSIAVAKAAADHLGISL 129
Cdd:PTZ00378 91 GERDGEADATLDPAEYTTEALQNSYFPRLLQLGARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPL 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 130 YHYL-------GGFNTKELPVPMMNIVNGGSHSSAPIAFQEFMILPVgAPSFKEALRWGTEVFHALAKILadRGLETTVG 202
Cdd:PTZ00378 171 FQYLralfgslTSVETFSMPQLCITFFGPGNPSTARLALKSVLFSPV-MPSGTVLRERMQKIFAAFHHFC--QSHNSSVR 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 203 DEGGFA-PKFEGTEDGVETILEAIKAAGLTPGEDVLLG--FDCAASEFYENGVYD--------------YTKFEGEgaAK 265
Cdd:PTZ00378 248 SDGSLHwDGFANLTDAVKLATEALRAVQLTPGTDVCLGlrMAASTTRVPATAVADggawkeakddcevlYSLFPGE--PD 325
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 266 RTSSEQVDYLEELVNKYP--IISIEDGLDEDDWDGWKELTDRLGDRVQLVGDDLLV-TNTEKLSEAIEKDISNSILIKVN 342
Cdd:PTZ00378 326 VTGDQLSEYVREQLQAVPdiVVYVEDTHCDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPC 405
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1224054089 343 QIGTLTETFDAIEMAKK-AGYTAVISHRSGETEDTTISDIAVATNAGQIKTGSLSRTDRVAKYNQLLRIEDQL 414
Cdd:PTZ00378 406 AIGTLSDVVEIVRAVGEdEGRAVTVLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
21-361 |
1.28e-07 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 53.29 E-value: 1.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 21 VEVEVYTASGAFGRGIVPSGASTGEYEA--VELRD-------GEDRYLGKGVQKAVDNVNNIIAETLVGVDVTNQQLIDR 91
Cdd:COG4948 4 TDIEVYPVRLPLKRPFTISRGTRTERDVvlVRVETddgitgwGEAVPGGTGAEAVAAALEEALAPLLIGRDPLDIEALWQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 92 MMIELDGTPNkgklgaNAILGVSIAVAKAAADHLGISLYHYLGGFNTKELPVpmmnivnGGSHSSAPIafqefmilpvga 171
Cdd:COG4948 84 RLYRALPGNP------AAKAAVDMALWDLLGKALGVPVYQLLGGKVRDRVPV-------YATLGIDTP------------ 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 172 psfkealrwgtEVFHALAKILADRGLeTTVgdeggfapKFEGTEDGVETILEAIKA--AGLtpGEDVLLGFDCaasefye 249
Cdd:COG4948 139 -----------EEMAEEAREAVARGF-RAL--------KLKVGGPDPEEDVERVRAvrEAV--GPDARLRVDA------- 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 250 NGVYDYtkfegEGAakrtsseqVDYLEELVnKYPIISIEDGLDEDDWDGWKELTDRLgdRVQLVGDDLLVTNTEkLSEAI 329
Cdd:COG4948 190 NGAWTL-----EEA--------IRLLRALE-DLGLEWIEQPLPAEDLEGLAELRRAT--PVPIAADESLTSRAD-FRRLI 252
|
330 340 350
....*....|....*....|....*....|..
gi 1224054089 330 EKDISNSILIKVNQIGTLTETFDAIEMAKKAG 361
Cdd:COG4948 253 EAGAVDIVNIKLSKVGGLTEALRIAALAEAHG 284
|
|
| MLE |
cd03318 |
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis, ... |
21-143 |
4.16e-03 |
|
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates. Some bacterial species are also capable of dehalogenating chloroaromatic compounds by the action of chloromuconate lactonizing enzymes (Cl-MLEs). MLEs are members of the enolase superfamily characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and that is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239434 [Multi-domain] Cd Length: 365 Bit Score: 39.22 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224054089 21 VEVEVYTASGA--FGRGIVPSGASTGeYEAVElrdgedrylgkGVQKAVDNVnniIAETLVGVDVTNqqlIDRMMIELDG 98
Cdd:cd03318 31 VLVRLTTSDGVvgIGEATTPGGPAWG-GESPE-----------TIKAIIDRY---LAPLLIGRDATN---IGAAMALLDR 92
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1224054089 99 TPnKGKLGANAilGVSIAVAKAAADHLGISLYHYLGGFNTKELPV 143
Cdd:cd03318 93 AV-AGNLFAKA--AIEMALLDAQGRRLGLPVSELLGGRVRDSLPV 134
|
|
| |
