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Conserved domains on  [gi|1224250973|ref|WP_092277663|]
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MULTISPECIES: tetratricopeptide repeat protein [Pseudomonas]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
44-137 6.71e-23

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.53  E-value: 6.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  44 PQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQAQYKLGSMFFHGEGVPANNVQAY 123
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90
                  ....*....|....
gi 1224250973 124 IVLKMAAVNGAEDA 137
Cdd:COG0790   196 EWYRKAAEQGDADA 209
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
44-137 6.71e-23

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.53  E-value: 6.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  44 PQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQAQYKLGSMFFHGEGVPANNVQAY 123
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90
                  ....*....|....
gi 1224250973 124 IVLKMAAVNGAEDA 137
Cdd:COG0790   196 EWYRKAAEQGDADA 209
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 63-98 1.13e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 46.01  E-value: 1.13e-07
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1224250973   63 AQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGH 98
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 63-97 6.54e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 44.05  E-value: 6.54e-07
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1224250973  63 AQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQG 97
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
44-137 6.71e-23

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.53  E-value: 6.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  44 PQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQAQYKLGSMFFHGEGVPANNVQAY 123
Cdd:COG0790   116 PQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKAL 195

                          90
                  ....*....|....
gi 1224250973 124 IVLKMAAVNGAEDA 137
Cdd:COG0790   196 EWYRKAAEQGDADA 209
TPR COG0790
TPR repeat [General function prediction only];
44-137 7.54e-23

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 91.14  E-value: 7.54e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  44 PQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQAQYKLGSMFFHGEGVPANNVQAY 123
Cdd:COG0790    80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                          90
                  ....*....|....
gi 1224250973 124 IVLKMAAVNGAEDA 137
Cdd:COG0790   160 EWYRKAAEQGDADA 173
TPR COG0790
TPR repeat [General function prediction only];
44-130 7.87e-20

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 83.44  E-value: 7.87e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  44 PQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQAQYKLGSMFFHGEGVPANNVQAY 123
Cdd:COG0790   152 PKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKAL 231


                  ....*..
gi 1224250973 124 IVLKMAA 130
Cdd:COG0790   232 RWLRKAA 238
TPR COG0790
TPR repeat [General function prediction only];
21-137 8.00e-17

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 75.35  E-value: 8.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  21 AHAQAGGNSLLIPAMGRCTLNTQPQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQ 100
Cdd:COG0790    21 AAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAE 100

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1224250973 101 AQYKLGSMFFHGEGVPANNVQAYIVLKMAAVNGAEDA 137
Cdd:COG0790   101 AQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADA 137
TPR COG0790
TPR repeat [General function prediction only];
44-96 5.33e-08

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 51.08  E-value: 5.33e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1224250973  44 PQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQ 96
Cdd:COG0790   188 PKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 63-98 1.13e-07

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 46.01  E-value: 1.13e-07
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1224250973   63 AQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGH 98
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 63-97 6.54e-07

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 44.05  E-value: 6.54e-07
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1224250973  63 AQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQG 97
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
TPR COG0790
TPR repeat [General function prediction only];
43-137 7.40e-06

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 44.92  E-value: 7.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1224250973  43 QPQDLTQALAACQKAADEGDAQAQYELGEFYYDGQNAPRDLDKALKFFEKASLQGHAQAQYKLGSMFFHGEGVPANNVQA 122
Cdd:COG0790     7 AAAAAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKA 86

                          90
                  ....*....|....*
gi 1224250973 123 YIVLKMAAVNGAEDA 137
Cdd:COG0790    87 LEWFEKAAEQGDAEA 101
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 99-133 8.12e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 41.01  E-value: 8.12e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 1224250973   99 AQAQYKLGSMFFHGEGVPANNVQAYIVLKMAAVNG 133
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 99-130 6.01e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 35.96  E-value: 6.01e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1224250973  99 AQAQYKLGSMFFHGEGVPANNVQAYIVLKMAA 130
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAA 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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